The network for 'negative regulation of rna biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of rna biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RPD3 Rpd3p 0.999
HHF1 Hhf1p 0.997
RAP1 Rap1p 0.996
RCO1 Rco1p 0.993
SIR2 Sir2p 0.989
HDA1 Hda1p 0.982
SIN3 Sin3p 0.982
RLF2 Rlf2p 0.975
RXT2 Rxt2p 0.969
PHO23 Pho23p 0.966
HHT1 Hht1p 0.952
CTI6 Cti6p 0.951
ISW2 Isw2p 0.925
SUM1 Sum1p 0.923
SIR4 Sir4p 0.922
SET2 Set2p 0.921
MED2 Med2p 0.916
SET1 Set1p 0.907
ASF1 Asf1p 0.894
SNF1 Snf1p 0.894
CYC8 Cyc8p 0.891
SDS3 Sds3p 0.884
SPT21 Spt21p 0.879
RTT106 Rtt106p 0.879
GAL11 Gal11p 0.872
RPN4 Rpn4p 0.863
PGD1 Pgd1p 0.853
SAS2 Sas2p 0.850
HAT1 Hat1p 0.838
RIM101 Rim101p 0.837
GCR2 Gcr2p 0.827
HOG1 Hog1p 0.822
FKH2 Fkh2p 0.817
YTA7 Yta7p 0.806
ORC2 Orc2p 0.798
SIN4 Sin4p 0.793
EAF3 Eaf3p 0.793
ACT1 Act1p 0.762
PHO4 Pho4p 0.761
NUT1 Nut1p 0.752
CDC14 Cdc14p 0.750
SPT16 Spt16p 0.749
FMP48 Fmp48p 0.742
ADR1 Adr1p 0.738
ORC5 Orc5p 0.733
RIF1 Rif1p 0.727
RLM1 Rlm1p 0.723
ROX3 Rox3p 0.711
UBP8 Ubp8p 0.699
RSC2 Rsc2p 0.696
RGR1 Rgr1p 0.692
HHF2 Hhf2p 0.674
CSE2 Cse2p 0.665
SSN3 Ssn3p 0.658
SWI4 Swi4p 0.656
NAT1 Nat1p 0.654
MET4 Met4p 0.652
SDC1 Sdc1p 0.646
IFH1 Ifh1p 0.643
ARP4 Arp4p 0.627
IES3 Ies3p 0.621
HTZ1 Htz1p 0.619
HTB2 Htb2p 0.617
SET3 Set3p 0.614
HDA3 Hda3p 0.614
NRG1 Nrg1p 0.612
SWD1 Swd1p 0.610
MED1 Med1p 0.607
RSC4 Rsc4p 0.605
MTR10 Mtr10p 0.599
HTB1 Htb1p 0.596
SIR3 Sir3p 0.593
SAS4 Sas4p 0.586
MOT1 Mot1p 0.585
CTK1 Ctk1p 0.581
TOM1 Tom1p 0.573
HMO1 Hmo1p 0.571
NHP6A Nhp6ap 0.569
CDC55 Cdc55p 0.559
SPT10 Spt10p 0.554
UME1 Ume1p 0.551
SLX5 Slx5p 0.540
CDC6 Cdc6p 0.535
STM1 Stm1p 0.532
SNT1 Snt1p 0.521
HIR2 Hir2p 0.520
GBP2 Gbp2p 0.508
HSP82 Hsp82p 0.508
HFI1 Hfi1p 0.508
CTF18 Ctf18p 0.508
SCH9 Sch9p 0.498
RIM20 Rim20p 0.497
DPB4 Dpb4p 0.495
RNR2 Rnr2p 0.493
CHL1 Chl1p 0.490
NTO1 Nto1p 0.490
MSN4 Msn4p 0.486
WHI3 Whi3p 0.483
TAF5 Taf5p 0.483
IXR1 Ixr1p 0.477
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.989
elt-6 Protein ELT-6 0.937
his-64 Protein HIS-64 0.843
his-61 Protein HIS-61 0.801
his-5 Protein HIS-5 0.750
his-1 Protein HIS-1 0.721
pha-4 Protein PHA-4 0.668
his-48 Protein HIS-48 0.641
hlh-2 Protein HLH-2 0.640
his-31 Protein HIS-31 0.574
his-29 Protein HIS-29 0.498
his-68 Protein HIS-68 0.443
mab-5 Protein MAB-5 0.385
hbl-1 Protein HBL-1 0.376
nhr-67 Protein NHR-67 0.348
egl-46 Protein EGL-46 0.342
mix-1 Protein MIX-1 0.307
nhr-2 Protein NHR-2 0.304
ceh-32 Protein CEH-32 0.278
mat-3 Protein MAT-3 0.269
his-3 Protein HIS-3 0.267
his-16 Protein HIS-16 0.228
lin-53 Protein LIN-53 0.225
cdt-2 Protein CDT-2 0.221
his-9 Protein HIS-9 0.217
daf-14 Protein DAF-14 0.187
hlh-1 Protein HLH-1 0.182
his-51 Protein HIS-51 0.172
plc-1 Protein PLC-1 0.170
rsp-1 Protein RSP-1 0.168
mes-4 Protein MES-4 0.161
prp-8 Protein PRP-8 0.159
let-502 Protein LET-502 0.156
bar-1 Protein BAR-1 0.155
ten-1 Protein TEN-1 0.155
F39B2.1 Protein F39B2.1 0.145
daf-1 Protein DAF-1 0.145
fkh-2 Protein FKH-2 0.142
tbx-8 Protein TBX-8 0.139
zip-7 Protein ZIP-7 0.137
unc-37 Protein UNC-37 0.136
atg-2 Protein ATG-2 0.135
let-418 Protein LET-418 0.131
ceh-27 Protein CEH-27 0.131
pop-1 Protein POP-1 0.129
nhr-25 Protein NHR-25 0.127
ran-1 Protein RAN-1 0.125
attf-2 Protein ATTF-2 0.124
daf-21 Protein DAF-21 0.124
his-38 Protein HIS-38 0.119
cnd-1 Protein CND-1 0.117
his-45 Protein HIS-45 0.114
pry-1 Protein PRY-1 0.107
unc-62 Protein UNC-62 0.105
glp-1 Protein GLP-1 0.105
ceh-38 Protein CEH-38 0.105
hcp-3 Protein HCP-3 0.101
csn-4 Protein CSN-4 0.100
mom-2 Protein MOM-2 0.097
fkb-6 Protein FKB-6 0.096
CELE_C23G10.8 Protein C23G10.8 0.096
daf-4 Protein DAF-4 0.095
lsy-2 Protein LSY-2 0.091
bet-2 Protein BET-2 0.091
wrm-1 Protein WRM-1 0.090
mex-5 Protein MEX-5 0.090
rgs-7 Protein RGS-7 0.090
dpy-30 Protein DPY-30 0.090
mep-1 Protein MEP-1 0.089
cam-1 Protein CAM-1 0.089
sel-12 Protein SEL-12 0.088
lsy-22 Protein LSY-22 0.088
lin-17 Protein LIN-17 0.088
npp-12 Protein NPP-12 0.088
sur-2 Protein SUR-2 0.087
his-46 Protein HIS-46 0.086
hda-1 Protein HDA-1 0.086
CELE_F54D5.5 Protein F54D5.5 0.085
fozi-1 Protein FOZI-1 0.085
D1081.8 Protein D1081.8 0.084
T20F7.1 Protein T20F7.1 0.083
mcm-2 Protein MCM-2 0.083
his-6 Protein HIS-6 0.082
npp-21 Protein NPP-21 0.081
lin-13 Protein LIN-13 0.081
flt-1 Protein FLT-1 0.080
daf-3 Protein DAF-3 0.079
egl-13 Protein EGL-13 0.078
T28F4.1 Protein T28F4.1 0.078
prpf-4 Protein PRPF-4 0.077
pdr-1 Protein PDR-1 0.077
eor-1 Protein EOR-1 0.077
egl-38 Protein EGL-38 0.076
dpy-22 Protein DPY-22 0.076
ccch-1 Protein CCCH-1 0.075
his-63 Protein HIS-63 0.075
F33H2.3 Protein F33H2.3 0.075
cul-2 Protein CUL-2 0.075
his-47 Protein HIS-47 0.073
his-72 Protein HIS-72 0.073
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.859
ndr2 nodal-related 2 0.825
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.751
gata6 GATA-binding protein 6 0.745
gli1 GLI-Kruppel family member 1 0.599
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.536
dlx3b distal-less homeobox gene 3b 0.500
jag2 jagged 2 0.421
twist3 twist3 0.420
notch1a notch homolog 1a 0.412
flh floating head 0.411
per3 period homolog 3 (Drosophila) 0.393
bmp2b bone morphogenetic protein 2b 0.392
dlx2a distal-less homeobox gene 2a 0.370
etv2 ets variant gene 2 0.361
sox9b SRY-box containing gene 9b 0.344
per2 period homolog 2 (Drosophila) 0.321
dlc deltaC 0.319
tfap2a transcription factor AP-2 alpha 0.315
gata4 GATA-binding protein 4 0.296
spaw southpaw 0.289
sox19b SRY-box containing gene 19b 0.276
neurog1 neurogenin 1 0.269
sox32 SRY-box containing gene 32 0.269
her15.1 hairy and enhancer of split-related 15.1 0.263
hmx1 H6 homeo box 1 0.243
sox19a SRY-box containing gene 19a 0.230
hnf1ba HNF1 homeobox Ba 0.229
snai1b snail homolog 1b (Drosophila) 0.228
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.223
sesn1 sestrin 1 0.208
mecom MDS1 and EVI1 complex locus 0.206
sox2 SRY-box containing gene 2 0.200
tal1 T-cell acute lymphocytic leukemia 1 0.199
fsta follistatin a 0.197
vasa vasa homolog 0.196
lhx1a LIM homeobox 1a 0.178
vsx1 visual system homeobox 1 homolog, chx10-like 0.173
wnt5b wingless-type MMTV integration site family, member 5b 0.170
sox10 SRY-box containing gene 10 0.166
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.165
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.165
wt1a wilms tumor 1a 0.163
dlx6a distal-less homeobox gene 6a 0.162
fgf8a fibroblast growth factor 8 a 0.160
foxa3 forkhead box A3 0.160
pcna proliferating cell nuclear antigen 0.158
hoxa13a homeo box A13a 0.157
foxg1a forkhead box G1a 0.156
tbx6 T-box gene 6 0.154
pitx2 paired-like homeodomain transcription factor 2 0.152
meis2.1 myeloid ecotropic viral integration site 2.1 0.150
ptf1a pancreas specific transcription factor, 1a 0.150
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.148
emx1 empty spiracles homeobox 1 0.148
rarab retinoic acid receptor, alpha b 0.143
tbx18 T-box 18 0.142
ascl1a achaete-scute complex-like 1a (Drosophila) 0.136
tll1 tolloid-like 1 0.135
fgf19 fibroblast growth factor 19 0.135
hoxb1b homeo box B1b 0.134
pax3a paired box gene 3a 0.134
her1 hairy-related 1 0.133
rarga retinoic acid receptor gamma a 0.133
cry1a cryptochrome 1a 0.131
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.128
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.126
her8a hairy-related 8a 0.125
robo3 roundabout homolog 3 0.125
gro1 groucho 1 0.125
cdx4 caudal type homeo box transcription factor 4 0.123
foxi3a forkhead box I3a 0.123
evx1 even-skipped homeobox 1 0.120
prox1 prospero-related homeobox gene 1 0.120
otpb orthopedia homolog b 0.119
neo1 neogenin 1 0.119
odz4 odd Oz/ten-m homolog 4 0.117
hoxb3a homeo box B3a 0.117
sall1a sal-like 1a (Drosophila) 0.114
foxi1 forkhead box I1 0.113
gata5 GATA-binding protein 5 0.113
chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) 0.110
fgf3 fibroblast growth factor 3 0.110
lhx5 LIM homeobox 5 0.110
ephb3a eph receptor B3a 0.110
her11 hairy-related 11 0.110
nkx2.5 NK2 transcription factor related 5 0.109
pou5f1 POU domain, class 5, transcription factor 1 0.105
klf4 Kruppel-like factor 4 0.105
axin2 axin 2 (conductin, axil) 0.105
pparg peroxisome proliferator activated receptor gamma 0.105
tbx16 T-box gene 16 0.104
hmgb1a high-mobility group box 1a 0.100
hmx3 homeo box (H6 family) 3 0.100
notch1b notch homolog 1b 0.099
runx1 runt-related transcription factor 1 0.098
grem2 gremlin 2, cysteine knot superfamily 0.094
gdf11 growth differentiation factor 11 0.092
axin1 axin 1 0.091
irx1b iroquois homeobox protein 1, b 0.091
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Snr1 Snf5-related 1 0.999
brk brinker 0.997
Mad Mothers against dpp 0.996
CTCF CG8591 gene product from transcript CG8591-RA 0.996
CtBP C-terminal Binding Protein 0.995
hep hemipterous 0.995
Iswi Imitation SWI 0.994
Sir2 CG5216 gene product from transcript CG5216-RA 0.994
E(spl) Enhancer of split 0.990
ato atonal 0.988
ash1 absent, small, or homeotic discs 1 0.988
gpp grappa 0.986
shn schnurri 0.986
kay kayak 0.986
Rpd3 CG7471 gene product from transcript CG7471-RA 0.985
Ubx Ultrabithorax 0.981
Trf2 TATA box binding protein-related factor 2 0.980
CycB Cyclin B 0.979
mor moira 0.975
D1 D1 chromosomal protein 0.971
Smr Smrter 0.969
E2f2 E2F transcription factor 2 0.968
His2Av Histone H2A variant 0.967
Su(var)205 Suppressor of variegation 205 0.964
dco discs overgrown 0.962
bowl brother of odd with entrails limited 0.960
salm spalt major 0.955
smt3 CG4494 gene product from transcript CG4494-RA 0.952
osa CG7467 gene product from transcript CG7467-RD 0.951
slmb supernumerary limbs 0.950
Kr Kruppel 0.948
Hel25E Helicase at 25E 0.943
mus209 mutagen-sensitive 209 0.940
N Notch 0.926
ush u-shaped 0.925
mam mastermind 0.924
pan pangolin 0.920
ara araucan 0.917
Scm Sex comb on midleg 0.915
toy twin of eyeless 0.914
Su(var)3-7 Suppressor of variegation 3-7 0.913
aop anterior open 0.908
brat brain tumor 0.907
sns sticks and stones 0.907
dom domino 0.905
Gap1 GTPase-activating protein 1 0.904
hth homothorax 0.903
Pcl Polycomblike 0.900
trx trithorax 0.898
Su(H) Suppressor of Hairless 0.896
tll tailless 0.895
Dref DNA replication-related element factor 0.894
p53 CG33336 gene product from transcript CG33336-RB 0.888
vas vasa 0.888
Ser Serrate 0.883
HLHm7 E(spl) region transcript m7 0.881
Tollo CG6890 gene product from transcript CG6890-RA 0.881
egg eggless 0.879
gsb gooseberry 0.876
ems empty spiracles 0.874
par-1 CG8201 gene product from transcript CG8201-RA 0.870
Optix CG18455 gene product from transcript CG18455-RA 0.868
svp seven up 0.864
Su(var)2-10 Suppressor of variegation 2-10 0.863
al aristaless 0.858
EcR Ecdysone receptor 0.856
B-H2 BarH2 0.847
sty sprouty 0.841
hkb huckebein 0.840
Su(z)2 Suppressor of zeste 2 0.834
ida imaginal discs arrested 0.833
cutlet CG33122 gene product from transcript CG33122-RA 0.830
Fmr1 CG6203 gene product from transcript CG6203-RC 0.830
arr arrow 0.829
mago mago nashi 0.829
pdm2 POU domain protein 2 0.829
sno strawberry notch 0.825
Abd-B Abdominal B 0.824
tup tailup 0.820
tin tinman 0.819
sna snail 0.813
pr-set7 CG3307 gene product from transcript CG3307-RC 0.806
eyg eyegone 0.805
esc extra sexcombs 0.805
dpp decapentaplegic 0.803
E(var)3-9 Enhancer of variegation 3-9 0.798
BEAF-32 Boundary element-associated factor of 32kD 0.797
slp1 sloppy paired 1 0.797
Bap170 Brahma associated protein 170kD 0.789
HLHmdelta E(spl) region transcript mdelta 0.786
phyl phyllopod 0.785
wapl wings apart-like 0.779
dac dachshund 0.779
Acf1 ATP-dependent chromatin assembly factor large subunit 0.777
bs blistered 0.771
sim single-minded 0.769
Nf-YC Nuclear factor Y-box C 0.767
tws twins 0.751
Dp DP transcription factor 0.746
Lam Lamin 0.746
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.652
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.609
Zfp36 zinc finger protein 36 0.563
Jun Jun oncogene 0.509
Ifitm3 interferon induced transmembrane protein 3 0.505
Nfib nuclear factor I/B 0.434
Id1 inhibitor of DNA binding 1 0.421
Tgfbr2 transforming growth factor, beta receptor II 0.406
Kdm6b lysine (K)-specific demethylase 6B 0.401
Vim vimentin 0.391
Tcfe2a transcription factor E2a 0.357
Errfi1 ERBB receptor feedback inhibitor 1 0.324
Pcna proliferating cell nuclear antigen 0.319
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.311
S100a8 S100 calcium binding protein A8 0.308
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.307
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.301
Rhob ras homolog gene family, member B 0.295
Btg2 BTG family, member 2 0.295
Eif4h eukaryotic translation initiation factor 4H 0.292
Fos FBJ osteosarcoma oncogene 0.284
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.273
Hoxc4 homeo box C4 0.272
Jak1 Janus kinase 1 0.272
Neurog1 neurogenin 1 0.271
Hoxb7 homeo box B7 0.269
Dusp1 dual specificity phosphatase 1 0.264
Socs3 suppressor of cytokine signaling 3 0.256
Hmgb1 high mobility group box 1 0.254
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.250
Dchs1 dachsous 1 (Drosophila) 0.234
Ptprk protein tyrosine phosphatase, receptor type, K, extracellular region 0.225
Ehmt2 euchromatic histone lysine N-methyltransferase 2 0.222
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.220
Klf4 Kruppel-like factor 4 (gut) 0.217
Hmgn2 high mobility group nucleosomal binding domain 2 0.213
Smad3 SMAD family member 3 0.213
Purb purine rich element binding protein B 0.205
Crybb3 crystallin, beta B3 0.204
Gtf3c2 general transcription factor IIIC, polypeptide 2, beta 0.200
Trim28 tripartite motif-containing 28 0.197
Dlg1 discs, large homolog 1 (Drosophila) 0.193
Met met proto-oncogene 0.192
Grin2d glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.191
S100a6 S100 calcium binding protein A6 0.191
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.187
Ier2 immediate early response 2 0.186
Gast gastrin 0.178
Klf6 Kruppel-like factor 6 0.177
Fgfr1 Fibroblast growth factor receptor 1 0.174
Tulp1 tubby like protein 1 0.172
Hand2 heart and neural crest derivatives expressed 2 0.172
Klf2 Kruppel-like factor 2 (lung) 0.165
Ahr aryl hydrocarbon receptor 0.165
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.165
Shox2 short stature homeobox 2 0.162
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.161
Nrp1 neuropilin 1 0.160
Lpl lipoprotein lipase 0.160
S100a9 S100 calcium binding protein A9 0.159
Cd9 CD9 molecule 0.159
Gabrr2 gamma-aminobutyric acid (GABA) receptor, rho 2 0.159
Hnrpd heterogeneous nuclear ribonucleoprotein D 0.156
Smc1a structural maintenance of chromosomes 1A 0.156
RGD1565591 similar to Ski protein 0.155
Hes1 hairy and enhancer of split 1 (Drosophila) 0.154
Smad7 SMAD family member 7 0.153
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.150
Akap1 A kinase (PRKA) anchor protein 1 0.148
Ssrp1 structure specific recognition protein 1 0.147
Pgam1 phosphoglycerate mutase 1 (brain) 0.147
Ubtf upstream binding transcription factor, RNA polymerase I 0.147
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.147
Tcf4 transcription factor 4 0.145
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.145
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.145
Lphn2 latrophilin 2 0.144
Kif1c kinesin family member 1C 0.144
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.143
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.143
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.135
Sox7 SRY (sex determining region Y)-box 7 0.135
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.134
Kcnt1 potassium channel, subfamily T, member 1 0.131
Wbp11 WW domain binding protein 11 0.131
Ccnd1 cyclin D1 0.129
Cd63 Cd63 molecule 0.129
Ublcp1 ubiquitin-like domain containing CTD phosphatase 1 0.128
Pou3f2 POU class 3 homeobox 2 0.128
Mgp matrix Gla protein 0.127
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.126
Cntn4 contactin 4 0.126
Adra2b adrenergic, alpha-2B-, receptor 0.126
Usf2 upstream transcription factor 2, c-fos interacting 0.126
Ldha lactate dehydrogenase A 0.125
Gspt1 G1 to S phase transition 1 0.125
Arhgap28 Rho GTPase activating protein 28 0.125
Nfya nuclear transcription factor-Y alpha 0.124
Cxxc5 CXXC finger 5 0.124
Crebbp CREB binding protein 0.124