The network for 'cellular hypotonic response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular hypotonic response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.

Name Description Probability Func Analog Organism
GLN3 Gln3p 0.156
MIG2 Mig2p 0.111
HAL5 Hal5p 0.079
MIG1 Mig1p 0.074
HXT3 Hxt3p 0.074
ROX1 Rox1p 0.065
DAL81 Dal81p 0.055
MIG3 Mig3p 0.048
VID24 Vid24p 0.048
KIC1 Kic1p 0.046
TOS3 Tos3p 0.038
MOT3 Mot3p 0.036
CBK1 Cbk1p 0.035
CUP9 Cup9p 0.034
YKR075C hypothetical protein 0.033
STP4 Stp4p 0.030
SWI1 Swi1p 0.029
YPL014W hypothetical protein 0.029
FAA2 Faa2p 0.029
TYE7 Tye7p 0.028
CAT8 Cat8p 0.028
YPR157W hypothetical protein 0.027
YAP5 Yap5p 0.027
ZAP1 Zap1p 0.027
MOB1 Mob1p 0.027
ICY1 Icy1p 0.026
SRD1 Srd1p 0.026
TOF2 Tof2p 0.026
ICS2 Ics2p 0.025
SSK2 Ssk2p 0.025
HAL1 Hal1p 0.025
VHS1 Vhs1p 0.025
IES1 Ies1p 0.025
TPO2 Tpo2p 0.024
IOC4 Ioc4p 0.024
YKL187C hypothetical protein 0.024
YOL038C-A hypothetical protein 0.023
HHO1 Hho1p 0.023
NUP157 Nup157p 0.023
TIP1 Tip1p 0.023
RPI1 Rpi1p 0.023
AGP2 Agp2p 0.023
SSU1 Ssu1p 0.023
SKS1 Sks1p 0.023
LEU2 Leu2p 0.023
IRC8 Irc8p 0.023
HOR2 Hor2p 0.022
GAT2 Gat2p 0.022
CSR2 Csr2p 0.022
ARP10 Arp10p 0.022
RTG3 Rtg3p 0.022
SPL2 Spl2p 0.022
SMP1 Smp1p 0.022
YLR264C-A hypothetical protein 0.022
SFL1 Sfl1p 0.022
YIR035C hypothetical protein 0.022
MER1 Mer1p 0.021
YNL194C hypothetical protein 0.021
ATF1 Atf1p 0.021
PHO12 Pho12p 0.021
YLR162W hypothetical protein 0.021
YMR102C hypothetical protein 0.021
SWC7 Swc7p 0.021
PSK2 Psk2p 0.021
NRG2 Nrg2p 0.021
PCT1 Pct1p 0.021
YAR068W hypothetical protein 0.020
TBS1 Tbs1p 0.020
RIB2 Rib2p 0.020
SFC1 Sfc1p 0.020
FMT1 Fmt1p 0.020
YBR013C hypothetical protein 0.020
STL1 Stl1p 0.020
YIR042C hypothetical protein 0.020
BSC1 Bsc1p 0.020
CRZ1 Crz1p 0.020
HMS1 Hms1p 0.020
STP1 Stp1p 0.020
GIP2 Gip2p 0.020
FOL2 Fol2p 0.020
NUM1 Num1p 0.019
ARG8 Arg8p 0.019
TRA1 Tra1p 0.019
CHA1 Cha1p 0.019
YER130C hypothetical protein 0.019
KRE29 Kre29p 0.019
ADH2 Adh2p 0.019
BSC2 Bsc2p 0.019
ATP6 Atp6p 0.019
GIS3 Gis3p 0.019
ZPS1 Zps1p 0.019
HOS3 Hos3p 0.019
CPD1 Cpd1p 0.019
CAB3 Cab3p 0.019
AUA1 Aua1p 0.018
YEL073C hypothetical protein 0.018
CUP1-1 Cup1-1p 0.018
RGS2 Rgs2p 0.018
RDS2 Rds2p 0.018
STB6 Stb6p 0.018
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CAB39 calcium binding protein 39 1.000
WNK4 WNK lysine deficient protein kinase 4 0.296
TRIP12 thyroid hormone receptor interactor 12 0.171
CTTN cortactin 0.081
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporters), member 2 0.064
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.041
MYL9 myosin, light chain 9, regulatory 0.029
STK39 serine threonine kinase 39 0.022
CALD1 caldesmon 1 0.018
OXSR1 oxidative-stress responsive 1 0.018
TPM1 tropomyosin 1 (alpha) 0.016
UBA6 ubiquitin-like modifier activating enzyme 6 0.015
MAP2K1 mitogen-activated protein kinase kinase 1 0.015
CSRP1 cysteine and glycine-rich protein 1 0.012
RAB10 RAB10, member RAS oncogene family 0.012
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Cldn16 claudin 16 0.416
Wnk4 WNK lysine deficient protein kinase 4 0.203
Adora3 adenosine A3 receptor 0.170
Slc12a2 solute carrier family 12, member 2 0.133
Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.064
Mb myoglobin 0.063
Scarb2 scavenger receptor class B, member 2 0.033
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.026
Slc26a4 solute carrier family 26, member 4 0.022
Edn1 endothelin 1 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
S100a6 S100 calcium binding protein A6 0.032
Lgals1 lectin, galactoside-binding, soluble, 1 0.014