The network for 'reproductive process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reproductive process

A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STE4 Ste4p 0.981
FAR1 Far1p 0.978
CDC24 Cdc24p 0.973
AGA1 Aga1p 0.970
SST2 Sst2p 0.965
FUS2 Fus2p 0.955
SPA2 Spa2p 0.952
FUS3 Fus3p 0.920
AGA2 Aga2p 0.916
FUS1 Fus1p 0.909
HHT1 Hht1p 0.899
SPO21 Spo21p 0.893
BEM1 Bem1p 0.892
CLA4 Cla4p 0.886
FIG2 Fig2p 0.877
HSP82 Hsp82p 0.829
CSI1 Csi1p 0.825
STE18 Ste18p 0.807
STE5 Ste5p 0.801
BMH2 Bmh2p 0.799
KAR5 Kar5p 0.799
FIG1 Fig1p 0.784
SSK1 Ssk1p 0.773
GIP1 Gip1p 0.770
MFA1 Mfa1p 0.765
MYO5 Myo5p 0.756
KIN1 Kin1p 0.741
GLC7 Glc7p 0.740
SSK2 Ssk2p 0.722
STE2 Ste2p 0.709
SPS22 Sps22p 0.693
CCT3 Cct3p 0.677
DIT2 Dit2p 0.673
STE20 Ste20p 0.658
PCI8 Pci8p 0.633
VPS13 Vps13p 0.620
CCT8 Cct8p 0.599
STE7 Ste7p 0.592
SLT2 Slt2p 0.587
BOI1 Boi1p 0.586
CRZ1 Crz1p 0.582
STE3 Ste3p 0.574
YDJ1 Ydj1p 0.571
LSG1 Lsg1p 0.561
PBS2 Pbs2p 0.534
RAS2 Ras2p 0.528
MSN2 Msn2p 0.503
TCP1 Tcp1p 0.483
MYO2 Myo2p 0.475
STE11 Ste11p 0.463
OSW1 Osw1p 0.454
DIT1 Dit1p 0.449
ADY3 Ady3p 0.448
FAR3 Far3p 0.439
SPT15 Spt15p 0.436
RAD53 Rad53p 0.436
SAW1 Saw1p 0.428
FAR7 Far7p 0.416
MPC54 Mpc54p 0.415
CWP2 Cwp2p 0.412
RHO1 Rho1p 0.412
RRI1 Rri1p 0.410
MKK2 Mkk2p 0.402
CNB1 Cnb1p 0.397
RPD3 Rpd3p 0.396
CMD1 Cmd1p 0.389
CHS3 Chs3p 0.387
CRR1 Crr1p 0.378
OSW2 Osw2p 0.377
GSC2 Gsc2p 0.369
PTP2 Ptp2p 0.369
HHF2 Hhf2p 0.364
FKS3 Fks3p 0.363
MF(ALPHA)1 Mf(alpha)1p 0.354
GPA1 Gpa1p 0.352
RAD9 Rad9p 0.351
SPO71 Spo71p 0.351
SNF1 Snf1p 0.346
GIM3 Gim3p 0.344
SIR4 Sir4p 0.341
POL32 Pol32p 0.341
CCT5 Cct5p 0.340
SSA3 Ssa3p 0.340
TPK1 Tpk1p 0.340
RGS2 Rgs2p 0.335
ACT1 Act1p 0.329
NPL6 Npl6p 0.328
PKH2 Pkh2p 0.326
HSL1 Hsl1p 0.321
MATALPHA1 Matalpha1p 0.319
EXO1 Exo1p 0.317
DTR1 Dtr1p 0.316
GFA1 Gfa1p 0.316
SNC2 Snc2p 0.316
PDS1 Pds1p 0.312
SLK19 Slk19p 0.309
SPR3 Spr3p 0.309
SWI4 Swi4p 0.306
PRB1 Prb1p 0.303
SNF12 Snf12p 0.302
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
nanos3 nanos homolog 3 0.888
shha sonic hedgehog a 0.774
dusp6 dual specificity phosphatase 6 0.723
piwil1 piwi-like 1 (Drosophila) 0.673
alcamb activated leukocyte cell adhesion molecule b 0.673
sox9a SRY-box containing gene 9a 0.645
foxa2 forkhead box A2 0.617
gli1 GLI-Kruppel family member 1 0.614
sox3 SRY-box containing gene 3 0.596
fgfr1a fibroblast growth factor receptor 1a 0.592
jag2 jagged 2 0.581
evx1 even-skipped homeobox 1 0.568
pax8 paired box gene 8 0.568
aurkb aurora kinase B 0.563
pbx4 pre-B-cell leukemia transcription factor 4 0.536
fn1 fibronectin 1 0.535
vasa vasa homolog 0.533
her6 hairy-related 6 0.519
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.507
crabp2a cellular retinoic acid binding protein 2, a 0.505
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.481
cct6a chaperonin containing TCP1, subunit 6A (zeta 1) 0.462
six1b sine oculis homeobox homolog 1b 0.461
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.460
gro1 groucho 1 0.449
eif3g eukaryotic translation initiation factor 3, subunit G 0.446
robo3 roundabout homolog 3 0.421
snrpc small nuclear ribonucleoprotein polypeptide C 0.416
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.412
smad1 MAD homolog 1 (Drosophila) 0.405
tll1 tolloid-like 1 0.405
gdf6a growth differentiation factor 6a 0.405
mib mind bomb 0.404
ntn1a netrin 1a 0.403
fancl Fanconi anemia, complementation group L 0.386
ptgs1 prostaglandin-endoperoxide synthase 1 0.359
ndr2 nodal-related 2 0.353
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.333
osr1 odd-skipped related 1 (Drosophila) 0.328
sox32 SRY-box containing gene 32 0.326
sox2 SRY-box containing gene 2 0.314
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.310
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.308
e2f5 E2F transcription factor 5 0.306
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.302
otx1b orthodenticle homolog 1b 0.293
hhip hedgehog interacting protein 0.289
tp53 tumor protein p53 0.285
myf5 myogenic factor 5 0.282
twist1a twist1a 0.264
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.262
pea3 ETS-domain transcription factor pea3 0.259
chd chordin 0.259
ascl1a achaete-scute complex-like 1a (Drosophila) 0.258
prox1 prospero-related homeobox gene 1 0.248
hoxa13b homeo box A13b 0.246
rspo1 R-spondin homolog (Xenopus laevis) 0.237
wnt11r wingless-type MMTV integration site family, member 11, related 0.236
prnprs3 prion protein, related sequence 3 0.235
musk muscle, skeletal, receptor tyrosine kinase 0.233
tardbp TAR DNA binding protein 0.228
zff9 zinc finger protein 9 0.227
s1pr2 sphingosine-1-phosphate receptor 2 0.224
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.220
pkd2 polycystic kidney disease 2 0.218
twist3 twist3 0.218
buc bucky ball 0.218
spry4 sprouty (Drosophila) homolog 4 0.218
gpr126 G protein-coupled receptor 126 0.217
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.214
tfap2a transcription factor AP-2 alpha 0.213
eif3d eukaryotic translation initiation factor 3, subunit D 0.212
unc5b unc-5 homolog B (C. elegans) 0.209
six4b sine oculis homeobox homolog 4b 0.206
eif3c eukaryotic translation initiation factor 3, subunit C 0.204
pob partial optokinetic response b 0.203
sox9b SRY-box containing gene 9b 0.202
notch1a notch homolog 1a 0.199
bmp15 bone morphogenetic protein 15 0.199
wt1a wilms tumor 1a 0.198
eomesa eomesodermin homolog a 0.198
cdc26 cell division cycle 26 homolog 0.196
bmp2a bone morphogenetic protein 2a 0.195
sart3 squamous cell carcinoma antigen recognised by T cells 3 0.194
sfrp1a secreted frizzled-related protein 1a 0.192
gpia glucose phosphate isomerase a 0.183
sec61al1 Sec61 alpha like 1 0.182
sf3b5 splicing factor 3b, subunit 5 0.180
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.179
dynlrb1 dynein, light chain, roadblock-type 1 0.179
foxi1 forkhead box I1 0.178
notch3 notch homolog 3 0.176
axin2 axin 2 (conductin, axil) 0.175
setb SET translocation (myeloid leukemia-associated) B 0.174
pax7a paired box gene 7a 0.173
rest RE1-silencing transcription factor 0.173
bmp4 bone morphogenetic protein 4 0.173
dharma dharma 0.168
piwil2 piwi-like 2 (Drosophila) 0.166
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.164
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
CREBBP CREB binding protein 0.988
ESR1 estrogen receptor 1 0.988
SP1 Sp1 transcription factor 0.987
EGFR epidermal growth factor receptor 0.983
TP53 tumor protein p53 0.972
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.959
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.954
RB1 retinoblastoma 1 0.950
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.949
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.930
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.906
CDK2 cyclin-dependent kinase 2 0.902
HDAC1 histone deacetylase 1 0.894
CAV1 caveolin 1, caveolae protein, 22kDa 0.856
SMAD4 SMAD family member 4 0.855
BRCA2 breast cancer 2, early onset 0.847
PABPC1 poly(A) binding protein, cytoplasmic 1 0.812
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.795
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.776
ATXN1 ataxin 1 0.765
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.751
RNPS1 RNA binding protein S1, serine-rich domain 0.748
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.725
SRPK1 SRSF protein kinase 1 0.711
RPA1 replication protein A1, 70kDa 0.709
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.691
ATF2 activating transcription factor 2 0.681
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.678
QKI quaking homolog, KH domain RNA binding (mouse) 0.677
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.655
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.654
EP300 E1A binding protein p300 0.654
SMAD3 SMAD family member 3 0.635
AR androgen receptor 0.632
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.612
EED embryonic ectoderm development 0.603
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.595
SRPK2 SRSF protein kinase 2 0.593
SRSF1 serine/arginine-rich splicing factor 1 0.576
NCOR1 nuclear receptor corepressor 1 0.576
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.575
NCOR2 nuclear receptor corepressor 2 0.570
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.564
FLNA filamin A, alpha 0.561
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.544
GSK3B glycogen synthase kinase 3 beta 0.529
MCM7 minichromosome maintenance complex component 7 0.520
MAPT microtubule-associated protein tau 0.504
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.500
SRSF2 serine/arginine-rich splicing factor 2 0.476
PRPF3 PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) 0.475
TFDP1 transcription factor Dp-1 0.472
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.470
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.458
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.455
FN1 fibronectin 1 0.452
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.452
MAPK14 mitogen-activated protein kinase 14 0.451
CCNA2 cyclin A2 0.440
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.430
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.427
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.424
EIF3B eukaryotic translation initiation factor 3, subunit B 0.417
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.399
E2F1 E2F transcription factor 1 0.393
MCM3 minichromosome maintenance complex component 3 0.383
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) 0.381
TCP1 t-complex 1 0.364
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.350
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.344
WAPAL wings apart-like homolog (Drosophila) 0.342
RBM39 RNA binding motif protein 39 0.339
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.337
CHERP calcium homeostasis endoplasmic reticulum protein 0.327
INSR insulin receptor 0.325
RARA retinoic acid receptor, alpha 0.321
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.320
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.317
SNW1 SNW domain containing 1 0.309
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.308
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.307
FGFR2 fibroblast growth factor receptor 2 0.306
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.305
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.301
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.298
WDR5 WD repeat domain 5 0.296
FGFR1 fibroblast growth factor receptor 1 0.295
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.291
GTPBP4 GTP binding protein 4 0.289
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.289
SNRPG small nuclear ribonucleoprotein polypeptide G 0.282
CD63 CD63 molecule 0.280
SRRM1 serine/arginine repetitive matrix 1 0.279
ACTB actin, beta 0.278
SMC3 structural maintenance of chromosomes 3 0.277
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.277
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 0.269
PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 0.268
LRRK2 leucine-rich repeat kinase 2 0.268
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.839
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.810
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.758
Gjb3 gap junction protein, beta 3 0.583
Eef2 eukaryotic translation elongation factor 2 0.555
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.536
Il8rb interleukin 8 receptor, beta 0.520
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.509
Trhr thyrotropin releasing hormone receptor 0.495
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.485
Hoxa2 homeo box A2 0.482
Chrm1 cholinergic receptor, muscarinic 1 0.470
Bmp6 bone morphogenetic protein 6 0.468
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.463
Tshb thyroid stimulating hormone, beta 0.463
Zic1 Zic family member 1 (odd-paired homolog, Drosophila) 0.460
Scnn1b sodium channel, nonvoltage-gated 1, beta 0.459
Col10a1 collagen, type X, alpha 1 0.458
Bcl2 B-cell CLL/lymphoma 2 0.452
Adra2a adrenergic, alpha-2A-, receptor 0.450
Ddr1 discoidin domain receptor tyrosine kinase 1 0.448
Cpxm2 carboxypeptidase X (M14 family), member 2 0.440
Prl3d1 Prolactin family 3, subfamily d, member 1 0.439
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.437
LOC246267 resection-induced TPI (rs11) 0.436
Insrr insulin receptor-related receptor 0.431
Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.430
Grk4 G protein-coupled receptor kinase 4 0.429
Edn1 endothelin 1 0.424
Anxa4 annexin A4 0.423
Ptgs2 prostaglandin-endoperoxide synthase 2 0.420
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.419
Olr857 olfactory receptor 857 0.418
Ghsr growth hormone secretagogue receptor 0.418
Bmp7 bone morphogenetic protein 7 0.418
Cd80 Cd80 molecule 0.418
Smgb neonatal submandibular gland protein B 0.413
Prdm2 PR domain containing 2, with ZNF domain 0.412
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.411
Lhb luteinizing hormone beta 0.408
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.406
Zfp36 zinc finger protein 36 0.406
Gabrr1 gamma-aminobutyric acid (GABA) receptor, rho 1 0.405
Igfbp5 insulin-like growth factor binding protein 5 0.404
Gja1 gap junction protein, alpha 1 0.404
Gpx3 glutathione peroxidase 3 0.401
Ednrb endothelin receptor type B 0.400
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.399
Odf4 outer dense fiber of sperm tails 4 0.398
Il12b interleukin 12B 0.396
Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.396
Il3 interleukin 3 0.394
Prpg1 proline-rich proteoglycan 1 0.391
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.390
Il1rn interleukin 1 receptor antagonist 0.387
Itgb1 integrin, beta 1 0.386
Fosl1 fos-like antigen 1 0.385
Trhr2 thyrotropin releasing hormone receptor 2 0.384
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.378
Igfbp6 insulin-like growth factor binding protein 6 0.378
Neurod2 neurogenic differentiation 2 0.376
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.375
Mc4r melanocortin 4 receptor 0.372
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.370
Pdpn podoplanin 0.366
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.365
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.365
Sgp158 proline-rich glycoprotein (sgp158) 0.365
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.361
Ttc36 tetratricopeptide repeat domain 36 0.360
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.359
Grin2d glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.358
Accn2 amiloride-sensitive cation channel 2, neuronal 0.356
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.355
Defb1 defensin beta 1 0.353
Myl9 myosin, light chain 9, regulatory 0.352
Twist2 twist homolog 2 (Drosophila) 0.350
Ppy pancreatic polypeptide 0.349
Tgfbr2 transforming growth factor, beta receptor II 0.349
Gast gastrin 0.348
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.347
Pitx3 paired-like homeodomain 3 0.344
Oxtr oxytocin receptor 0.343
Aqp9 aquaporin 9 0.341
Plau plasminogen activator, urokinase 0.339
Cand1 cullin-associated and neddylation-dissociated 1 0.338
Foxd1 forkhead box D1 0.338
Kcnk3 potassium channel, subfamily K, member 3 0.336
Gucy2f guanylate cyclase 2F 0.335
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.335
Duox2 dual oxidase 2 0.335
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.334
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.333
Foxi2 forkhead box I2 0.329
Anxa2 annexin A2 0.329
Sprr1al small proline-rich protein 1A-like 0.329
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.328
Psg29 pregnancy-specific glycoprotein 29 0.328
Fbxo23 F-box only protein 23 0.326
Alpi alkaline phosphatase, intestinal 0.325