The network for 'synaptonemal complex assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

synaptonemal complex assembly

The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.

Name Description Probability Func Analog Organism
ZIP1 Zip1p 0.913
RED1 Red1p 0.874
MEK1 Mek1p 0.586
PCH2 Pch2p 0.294
SMC4 Smc4p 0.207
SPO11 Spo11p 0.205
NDT80 Ndt80p 0.192
BRN1 Brn1p 0.180
MND1 Mnd1p 0.174
CST9 Cst9p 0.169
IME2 Ime2p 0.154
HOP1 Hop1p 0.153
MSH4 Msh4p 0.132
HFM1 Hfm1p 0.112
ZIP2 Zip2p 0.107
PDS1 Pds1p 0.105
SPO22 Spo22p 0.054
DMC1 Dmc1p 0.053
SMC2 Smc2p 0.045
MSH5 Msh5p 0.041
PDS5 Pds5p 0.036
CSM4 Csm4p 0.035
HSL1 Hsl1p 0.035
ECM11 Ecm11p 0.033
MAM1 Mam1p 0.032
SRD1 Srd1p 0.024
CLB6 Clb6p 0.023
LEU2 Leu2p 0.023
MCD1 Mcd1p 0.022
REC104 Rec104p 0.021
HOP2 Hop2p 0.021
REC102 Rec102p 0.021
ZPS1 Zps1p 0.020
ARP10 Arp10p 0.020
YLR162W hypothetical protein 0.020
YLR264C-A hypothetical protein 0.020
YOL038C-A hypothetical protein 0.020
SPC42 Spc42p 0.019
MER1 Mer1p 0.019
NUP82 Nup82p 0.019
GLG2 Glg2p 0.019
SPO16 Spo16p 0.018
CAK1 Cak1p 0.018
GAL2 Gal2p 0.018
CHA1 Cha1p 0.018
CUP1-1 Cup1-1p 0.017
IME4 Ime4p 0.017
SPL2 Spl2p 0.017
HXT3 Hxt3p 0.016
PTI1 Pti1p 0.016
CDC20 Cdc20p 0.016
PCL9 Pcl9p 0.016
SPR3 Spr3p 0.016
YIL151C hypothetical protein 0.016
YAR068W hypothetical protein 0.015
ORC6 Orc6p 0.015
ATP6 Atp6p 0.015
SSP1 Ssp1p 0.015
SAE3 Sae3p 0.015
SRT1 Srt1p 0.015
YPR157W hypothetical protein 0.015
YBR013C hypothetical protein 0.015
RAD53 Rad53p 0.015
RNP1 Rnp1p 0.015
MEI4 Mei4p 0.014
YBL044W hypothetical protein 0.014
YOL013W-A hypothetical protein 0.014
YLR042C hypothetical protein 0.014
SHU1 Shu1p 0.014
PCL10 Pcl10p 0.014
HPF1 Hpf1p 0.014
SPO13 Spo13p 0.014
ARG8 Arg8p 0.014
CSM3 Csm3p 0.013
OPT2 Opt2p 0.013
YJL181W hypothetical protein 0.013
AUA1 Aua1p 0.013
SPS4 Sps4p 0.013
KNH1 Knh1p 0.013
ICS2 Ics2p 0.013
CPD1 Cpd1p 0.013
CLB1 Clb1p 0.013
YGL081W hypothetical protein 0.013
EST2 Est2p 0.013
SPO74 Spo74p 0.013
IZH4 Izh4p 0.013
YOR365C hypothetical protein 0.013
SCC2 Scc2p 0.013
YML053C hypothetical protein 0.012
YCG1 Ycg1p 0.012
URA3 Ura3p 0.012
ALT2 Alt2p 0.012
COS12 Cos12p 0.012
AQY2 Aqy2p 0.012
YGL015C hypothetical protein 0.012
BBP1 Bbp1p 0.012
HST3 Hst3p 0.012
YKR075C hypothetical protein 0.012
FMT1 Fmt1p 0.012
DIC1 Dic1p 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
ucr-2.3 Protein UCR-2.3 0.456
htp-1 Protein HTP-1 0.312
duo-1 Protein DUO-1 0.248
F13D12.5 Protein F13D12.5 0.194
glh-3 Protein GLH-3 0.165
hpo-32 Protein HPO-32 0.127
him-3 Protein HIM-3 0.124
D1081.7 Protein D1081.7 0.122
F09G2.2 Protein F09G2.2 0.109
rfc-4 Protein RFC-4 0.095
iff-1 Protein IFF-1 0.093
mcm-5 Protein MCM-5 0.090
klp-7 Protein KLP-7 0.086
W03G9.3 Protein W03G9.3 0.085
ZC410.3 Protein ZC410.3 0.085
K11H3.4 Protein K11H3.4 0.082
pgl-1 Protein PGL-1 0.077
ZK678.3 Protein ZK678.3 0.077
got-2.1 Protein GOT-2.1 0.077
mre-11 Protein MRE-11 0.077
vha-18 Protein VHA-18 0.074
zen-4 Protein ZEN-4 0.071
wago-1 Protein WAGO-1 0.071
T28A8.6 Protein T28A8.6 0.070
immt-2 Protein IMMT-2 0.069
bub-1 Protein BUB-1 0.067
ife-3 Protein IFE-3 0.062
F58E10.3 Protein F58E10.3 0.060
elpc-3 Protein ELPC-3 0.058
csr-1 Protein CSR-1 0.058
D2005.4 Protein D2005.4 0.053
nxf-2 Protein NXF-2 0.053
ZC434.8 Protein ZC434.8 0.052
san-1 Protein SAN-1 0.052
zim-3 Protein ZIM-3 0.052
mcm-6 Protein MCM-6 0.052
cyk-1 Protein CYK-1 0.050
skr-17 Protein SKR-17 0.048
plk-1 Protein PLK-1 0.047
cyk-4 Protein CYK-4 0.046
csc-1 Protein CSC-1 0.046
smc-5 Protein SMC-5 0.043
C55B7.11 Protein C55B7.11 0.042
W03C9.2 Protein W03C9.2 0.041
F56C9.6 Protein F56C9.6 0.041
C48B4.10 Protein C48B4.10 0.041
glh-1 Protein GLH-1 0.041
CELE_W02A11.1 Protein W02A11.1 0.041
C05C10.2 Protein C05C10.2 0.040
npp-18 Protein NPP-18 0.040
F01G4.4 Protein F01G4.4 0.040
F20A1.9 Protein F20A1.9 0.039
C13B4.1 Protein C13B4.1 0.039
skr-2 Protein SKR-2 0.039
ppw-2 Protein PPW-2 0.038
T10F2.2 Protein T10F2.2 0.036
F33D11.10 Protein F33D11.10 0.034
ZK418.8 Protein ZK418.8 0.033
CELE_T02C12.3 Protein T02C12.3 0.032
R07B7.2 Protein R07B7.2 0.031
CELE_C38D4.4 Protein C38D4.4 0.031
rnp-8 Protein RNP-8 0.030
K09H9.7 Protein K09H9.7 0.030
set-22 Protein SET-22 0.029
F55G1.5 Protein F55G1.5 0.029
CELE_D1046.2 Protein D1046.2 0.028
ect-2 Protein ECT-2 0.027
F35G12.5 Protein F35G12.5 0.026
CELE_C34D4.10 Protein C34D4.10 0.026
C48B4.6 Protein C48B4.6 0.026
lst-3 Protein LST-3 0.023
glh-4 Protein GLH-4 0.023
fbxa-101 Protein FBXA-101 0.023
hil-5 Protein HIL-5 0.023
CELE_C24H12.5 Protein C24H12.5 0.022
F57A10.4 Protein F57A10.4 0.022
K01G5.5 Protein K01G5.5 0.022
CELE_C56A3.8 Protein C56A3.8 0.022
pgl-2 Protein PGL-2 0.022
mrp-7 Protein MRP-7 0.021
F21F3.4 Protein F21F3.4 0.021
hcf-1 Protein HCF-1 0.021
K08E3.4 Protein K08E3.4 0.020
toe-1 Protein TOE-1 0.020
klp-18 Protein KLP-18 0.020
T02G5.12 Protein T02G5.12 0.020
T12F5.2 Protein T12F5.2 0.019
gpd-4 Protein GPD-4 0.019
CELE_C29A12.1 Protein C29A12.1 0.018
syx-4 Protein SYX-4 0.018
C18A3.2 Protein C18A3.2 0.018
asb-1 Protein ASB-1 0.018
brc-1 Protein BRC-1 0.017
bath-42 Protein BATH-42 0.017
prg-2 Protein PRG-2 0.017
gop-2 Protein GOP-2 0.017
T19H12.2 Protein T19H12.2 0.017
cpb-1 Protein CPB-1 0.017
inx-21 Protein INX-21 0.016
C46A5.6 Protein C46A5.6 0.016
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccna2 cyclin A2 0.990
Ccnb1 cyclin B1 0.957
Smc1a structural maintenance of chromosomes 1A 0.917
Mecp2 methyl CpG binding protein 2 0.869
Prc1 protein regulator of cytokinesis 1 0.500
Birc5 baculoviral IAP repeat-containing 5 0.478
Ccnb2 cyclin B2 0.448
Kif20a kinesin family member 20A 0.329
Ncaph non-SMC condensin I complex, subunit H 0.308
Ccne1 cyclin E1 0.275
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.268
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.221
Ckap2 cytoskeleton associated protein 2 0.220
Rrm2 ribonucleotide reductase M2 0.208
Kif11 kinesin family member 11 0.189
Neurl1a neuralized homolog 1A (Drosophila) 0.153
Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.144
Nxf2 nuclear RNA export factor 2 0.135
Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) 0.135
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.134
Cks2 CDC28 protein kinase regulatory subunit 2 0.128
Nasp nuclear autoantigenic sperm protein (histone-binding) 0.115
Top2a topoisomerase (DNA) II alpha 0.113
2810417H13Rik RIKEN cDNA 2810417H13 gene 0.110
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.109
Ppih peptidyl prolyl isomerase H 0.109
Kif23 kinesin family member 23 0.097
Pcna proliferating cell nuclear antigen 0.083
Ptov1 prostate tumor over expressed gene 1 0.082
Csnk1g2 casein kinase 1, gamma 2 0.080
Cdca8 cell division cycle associated 8 0.074
Cdk2 cyclin-dependent kinase 2 0.069
Smc2 structural maintenance of chromosomes 2 0.068
Ints9 integrator complex subunit 9 0.068
Cpeb2 cytoplasmic polyadenylation element binding protein 2 0.066
Aurka aurora kinase A 0.065
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.064
Racgap1 Rac GTPase-activating protein 1 0.063
Cdk1 cyclin-dependent kinase 1 0.063
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.062
Usp21 ubiquitin specific peptidase 21 0.057
C330027C09Rik RIKEN cDNA C330027C09 gene 0.057
Cdca7 cell division cycle associated 7 0.054
Nuf2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.051
Tsc2 tuberous sclerosis 2 0.049
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.047
Kif22 kinesin family member 22 0.047
Dctn1 dynactin 1 0.047
Plk4 polo-like kinase 4 (Drosophila) 0.046
Rnf2 ring finger protein 2 0.045
Ldb1 LIM domain binding 1 0.042
Supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.041
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.041
Stk31 serine threonine kinase 31 0.040
Hmgb2 high mobility group box 2 0.040
Pbk PDZ binding kinase 0.039
Kif1b kinesin family member 1B 0.038
Rnf11 ring finger protein 11 0.036
Aurkb aurora kinase B 0.035
Med16 mediator complex subunit 16 0.035
Cdk4 cyclin-dependent kinase 4 0.033
Tk1 thymidine kinase 1 0.032
Melk maternal embryonic leucine zipper kinase 0.031
Fam126b family with sequence similarity 126, member B 0.031
Adcy9 adenylate cyclase 9 0.031
Ube2c ubiquitin-conjugating enzyme E2C 0.031
Tmpo thymopoietin 0.031
Cdca5 cell division cycle associated 5 0.031
Vps16 vacuolar protein sorting 16 (yeast) 0.031
Sycp2 synaptonemal complex protein 2 0.031
Tesk1 testis specific protein kinase 1 0.030
Ccdc99 coiled-coil domain containing 99 0.030
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.030
Rrm1 ribonucleotide reductase M1 0.030
Skiv2l superkiller viralicidic activity 2-like (S. cerevisiae) 0.030
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.029
Dnmt3a DNA methyltransferase 3A 0.029
Vps72 vacuolar protein sorting 72 (yeast) 0.028
Mki67 antigen identified by monoclonal antibody Ki 67 0.027
Aamp angio-associated migratory protein 0.027
Rbck1 RanBP-type and C3HC4-type zinc finger containing 1 0.026
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.025
Cpeb4 cytoplasmic polyadenylation element binding protein 4 0.025
Eea1 early endosome antigen 1 0.025
Rybp RING1 and YY1 binding protein 0.025
Plk1 polo-like kinase 1 (Drosophila) 0.025
Rad51 RAD51 homolog (S. cerevisiae) 0.024
Anln anillin, actin binding protein 0.024
Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.024
Cenph centromere protein H 0.024
2610039C10Rik RIKEN cDNA 2610039C10 gene 0.023
Samd8 sterile alpha motif domain containing 8 0.023
Trim59 tripartite motif-containing 59 0.023
Coro1b coronin, actin binding protein 1B 0.023
Dna2 DNA replication helicase 2 homolog (yeast) 0.023
Kif2c kinesin family member 2C 0.022
Prpf8 pre-mRNA processing factor 8 0.021
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.021
Tex12 testis expressed gene 12 0.021
Hnrnpl heterogeneous nuclear ribonucleoprotein L 0.021
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Rattus norvegicus
Name Description Probability Func Analog Organism