The network for 'histone modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone modification

The covalent alteration of one or more amino acid residues within a histone protein.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HHT1 Hht1p 1.000
TRA1 Tra1p 1.000
GCN5 Gcn5p 1.000
ADA2 Ada2p 1.000
SPT8 Spt8p 0.999
SET1 Set1p 0.999
HFI1 Hfi1p 0.998
BDF1 Bdf1p 0.995
SWD3 Swd3p 0.995
SGF29 Sgf29p 0.993
TAF5 Taf5p 0.993
NGG1 Ngg1p 0.988
TAF6 Taf6p 0.987
SWD1 Swd1p 0.983
EPL1 Epl1p 0.978
SPT20 Spt20p 0.978
EAF1 Eaf1p 0.977
SPT7 Spt7p 0.977
SDC1 Sdc1p 0.976
SET2 Set2p 0.969
SIN3 Sin3p 0.967
SUS1 Sus1p 0.965
SNT1 Snt1p 0.960
RTF1 Rtf1p 0.957
HDA1 Hda1p 0.952
UBP8 Ubp8p 0.949
SPT3 Spt3p 0.947
ASF1 Asf1p 0.944
YNG1 Yng1p 0.937
ESA1 Esa1p 0.934
SGF73 Sgf73p 0.930
RCO1 Rco1p 0.909
YNG2 Yng2p 0.894
SPP1 Spp1p 0.880
TAF10 Taf10p 0.870
HOS2 Hos2p 0.863
YAF9 Yaf9p 0.805
EAF5 Eaf5p 0.728
RPD3 Rpd3p 0.723
HDA3 Hda3p 0.703
LEO1 Leo1p 0.676
TAF12 Taf12p 0.636
ARP4 Arp4p 0.632
RTT106 Rtt106p 0.576
SIF2 Sif2p 0.532
SWI4 Swi4p 0.519
CKS1 Cks1p 0.516
SGF11 Sgf11p 0.505
HHO1 Hho1p 0.487
DPB3 Dpb3p 0.480
SET3 Set3p 0.479
YTA7 Yta7p 0.477
SPT16 Spt16p 0.449
BRE2 Bre2p 0.439
HDA2 Hda2p 0.434
RSC4 Rsc4p 0.430
FPR4 Fpr4p 0.423
SPT5 Spt5p 0.422
HIF1 Hif1p 0.420
ELP6 Elp6p 0.417
HOS4 Hos4p 0.412
TAF9 Taf9p 0.403
RSC1 Rsc1p 0.401
CLB1 Clb1p 0.390
EAF6 Eaf6p 0.386
NAT1 Nat1p 0.369
ESF1 Esf1p 0.369
CAB3 Cab3p 0.344
SEN1 Sen1p 0.328
SDS3 Sds3p 0.316
ELP4 Elp4p 0.311
SAP190 Sap190p 0.294
SWI5 Swi5p 0.292
CLB2 Clb2p 0.289
VPS64 Vps64p 0.282
RTT109 Rtt109p 0.282
PHO80 Pho80p 0.270
SSN3 Ssn3p 0.260
HHT2 Hht2p 0.253
RSC8 Rsc8p 0.248
PEX22 Pex22p 0.244
THP1 Thp1p 0.234
CTR9 Ctr9p 0.230
GLC7 Glc7p 0.221
CDC6 Cdc6p 0.211
SIR2 Sir2p 0.202
CMD1 Cmd1p 0.200
ZDS1 Zds1p 0.198
SWI1 Swi1p 0.196
ISW1 Isw1p 0.190
RPB3 Rpb3p 0.184
YAT1 Yat1p 0.183
HAT1 Hat1p 0.176
CTI6 Cti6p 0.163
FKH2 Fkh2p 0.156
DDC1 Ddc1p 0.156
CAC2 Cac2p 0.154
ETP1 Etp1p 0.154
PEX2 Pex2p 0.153
HIR2 Hir2p 0.149
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
his-5 Protein HIS-5 0.621
his-1 Protein HIS-1 0.525
attf-2 Protein ATTF-2 0.504
his-50 Protein HIS-50 0.450
his-46 Protein HIS-46 0.386
his-31 Protein HIS-31 0.318
sdc-1 Protein SDC-1 0.298
nasp-1 Protein NASP-1 0.257
nfya-1 Protein NFYA-1 0.232
B0464.2 Protein B0464.2 0.231
his-64 Protein HIS-64 0.226
Y87G2A.1 Protein Y87G2A.1 0.201
F33H2.3 Protein F33H2.3 0.166
ubr-1 Protein UBR-1 0.164
apr-1 Protein APR-1 0.162
wrm-1 Protein WRM-1 0.157
ada-2 Protein ADA-2 0.151
R05D3.2 Protein R05D3.2 0.143
mes-6 Protein MES-6 0.138
his-42 Protein HIS-42 0.137
R07G3.7 Protein R07G3.7 0.133
spr-5 Protein SPR-5 0.132
zyg-9 Protein ZYG-9 0.132
CELE_Y11D7A.7 Protein Y11D7A.7 0.127
bmk-1 Protein BMK-1 0.125
hil-2 Protein HIL-2 0.123
F54C9.9 Protein F54C9.9 0.122
F33H1.4 Protein F33H1.4 0.122
his-16 Protein HIS-16 0.121
dcr-1 Protein DCR-1 0.113
CELE_Y41E3.11 Protein Y41E3.11 0.111
cks-1 Protein CKS-1 0.110
egl-18 Protein EGL-18 0.108
lst-3 Protein LST-3 0.108
C53B4.4 Protein C53B4.4 0.104
kle-2 Protein KLE-2 0.103
pqn-59 Protein PQN-59 0.102
rnp-6 Protein RNP-6 0.100
his-38 Protein HIS-38 0.096
sip-1 Protein SIP-1 0.095
hyls-1 Protein HYLS-1 0.091
brf-1 Protein BRF-1 0.087
F35G12.4 Protein F35G12.4 0.086
CELE_F19F10.9 Protein F19F10.9 0.084
rfc-4 Protein RFC-4 0.083
met-1 Protein MET-1 0.082
bra-2 Protein BRA-2 0.082
hmg-4 Protein HMG-4 0.082
T20F7.1 Protein T20F7.1 0.079
F33E11.3 Protein F33E11.3 0.077
iff-1 Protein IFF-1 0.074
swsn-4 Protein SWSN-4 0.074
T19H12.2 Protein T19H12.2 0.072
vab-1 Protein VAB-1 0.071
dsh-2 Protein DSH-2 0.070
F52G3.1 Protein F52G3.1 0.070
R11A8.7 Protein R11A8.7 0.070
lin-36 Protein LIN-36 0.069
sop-2 Protein SOP-2 0.067
egl-27 Protein EGL-27 0.067
spd-1 Protein SPD-1 0.066
smc-3 Protein SMC-3 0.066
CELE_B0238.11 Protein B0238.11 0.066
cfim-2 Protein CFIM-2 0.064
vps-37 Protein VPS-37 0.063
mdt-19 Protein MDT-19 0.063
CELE_C25A1.4 Protein C25A1.4 0.062
nol-5 Protein NOL-5 0.061
cdc-6 Protein CDC-6 0.061
pfs-2 Protein PFS-2 0.060
hcp-3 Protein HCP-3 0.058
C49H3.6 Protein C49H3.6 0.058
top-2 Protein TOP-2 0.057
nfx-1 Protein NFX-1 0.056
F49E8.7 Protein F49E8.7 0.056
hlh-11 Protein HLH-11 0.055
Y45G12B.2 Protein Y45G12B.2 0.054
F20D12.2 Protein F20D12.2 0.053
npp-21 Protein NPP-21 0.051
asd-1 Protein ASD-1 0.051
sta-1 Protein STA-1 0.050
his-61 Protein HIS-61 0.050
dpff-1 Protein DPFF-1 0.050
lin-5 Protein LIN-5 0.049
M01F1.8 Protein M01F1.8 0.049
CELE_Y57G11C.9 Protein Y57G11C.9 0.049
CELE_F23B12.7 Protein F23B12.7 0.048
W04D2.6 Protein W04D2.6 0.047
hda-1 Protein HDA-1 0.047
cec-5 Protein CEC-5 0.047
skp-1 Protein SKP-1 0.047
CELE_C17E4.6 Protein C17E4.6 0.047
rnf-113 Protein RNF-113 0.047
klp-18 Protein KLP-18 0.047
unc-40 Protein UNC-40 0.046
C27C12.1 Protein C27C12.1 0.044
ZK430.7 Protein ZK430.7 0.044
mep-1 Protein MEP-1 0.043
trr-1 Protein TRR-1 0.043
usp-46 Protein USP-46 0.043
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.441
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.424
prdm9 PR domain containing 9 0.366
smyd2a SET and MYND domain containing 2a 0.354
mll4b myeloid/lymphoid or mixed-lineage leukemia 4b 0.351
brd4 bromodomain containing 4 0.351
prdm2b PR domain containing 2, with ZNF domain b 0.328
suv39h1a suppressor of variegation 3-9 homolog 1a 0.316
lars leucyl-tRNA synthetase 0.260
twist1a twist1a 0.230
nrp1a neuropilin 1a 0.227
rbb4 retinoblastoma binding protein 4 0.227
aurkb aurora kinase B 0.218
setd2 SET domain containing 2 0.214
ehmt1a euchromatic histone-lysine N-methyltransferase 1a 0.209
nasp nuclear autoantigenic sperm protein (histone-binding) 0.208
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.201
suv39h1b suppressor of variegation 3-9 homolog 1b 0.198
nrp1b neuropilin 1b 0.189
myog myogenin 0.183
sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.177
myf5 myogenic factor 5 0.175
setd8b SET domain containing (lysine methyltransferase) 8b 0.171
rcc2 regulator of chromosome condensation 2 0.166
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.164
prdm11 PR domain containing 11 0.162
whsc1l1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.162
hcfc1a host cell factor C1a 0.158
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.157
ehmt1b euchromatic histone-lysine N-methyltransferase 1b 0.154
tal1 T-cell acute lymphocytic leukemia 1 0.145
setdb1b SET domain, bifurcated 1b 0.140
suv420h2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.130
suv420h1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.126
setd5 SET domain containing 5 0.120
ube2i ubiquitin-conjugating enzyme E2I 0.118
smyd3 SET and MYND domain containing 3 0.116
sephs1 selenophosphate synthetase 1 0.114
prdm14 PR domain containing 14 0.109
ehmt2 euchromatic histone-lysine N-methyltransferase 2 0.109
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.105
kdrl kinase insert domain receptor like 0.104
setdb1a SET domain, bifurcated 1a 0.097
smc3 structural maintenance of chromosomes 3 0.095
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.091
mll4a myeloid/lymphoid or mixed-lineage leukemia 4a 0.089
rbb4l retinoblastoma binding protein 4, like 0.089
hdac1 histone deacetylase 1 0.088
sass6 spindle assembly 6 homolog (C. elegans) 0.087
mll2 myeloid/lymphoid or mixed-lineage leukemia 2 0.086
eef2k elongation factor-2 kinase 0.085
mpx myeloid-specific peroxidase 0.084
prdm8b PR domain containing 8b 0.084
esco2 establishment of cohesion 1 homolog 2 0.083
ncaph non-SMC condensin I complex, subunit H 0.081
gro1 groucho 1 0.076
rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.075
smyd1a SET and MYND domain containing 1a 0.074
brd3a bromodomain containing 3a 0.072
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.072
ggnbp2 gametogenetin binding protein 2 0.072
phf23a PHD finger protein 23a 0.071
stk35l serine/threonine kinase 35, like 0.069
wt1b wilms tumor 1b 0.069
smyd5 SMYD family member 5 0.067
cry1a cryptochrome 1a 0.065
zc4h2 zinc finger, C4H2 domain containing 0.064
cse1l chromosome segregation 1-like (S. cerevisiae) 0.062
h3f3a H3 histone, family 3A 0.060
ing3 inhibitor of growth family, member 3 0.058
palb2 partner and localizer of BRCA2 0.058
wu:fv91b12 wu:fv91b12 0.057
ccnb2 cyclin B2 0.057
phax phosphorylated adaptor for RNA export 0.057
apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.056
orc5 origin recognition complex, subunit 5 0.056
gtf2f2a general transcription factor IIF, polypeptide 2a 0.054
pcna proliferating cell nuclear antigen 0.054
ssrp1a structure specific recognition protein 1a 0.054
zfyve26 zinc finger, FYVE domain containing 26 0.053
tfip11 tuftelin interacting protein 11 0.053
prdm1b PR domain containing 1b, with ZNF domain 0.052
mcrs1 microspherule protein 1 0.051
btg1 B-cell translocation gene 1 0.051
foxd3 forkhead box D3 0.050
nsd1b nuclear receptor binding SET domain protein 1b 0.049
mef2ca myocyte enhancer factor 2ca 0.049
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.048
prdm4 PR domain containing 4 0.048
smad2 MAD homolog 2 (Drosophila) 0.047
cmyb transcription factor cmyb 0.046
marcksb myristoylated alanine rich protein kinase C substrate b 0.046
tra2b transformer 2 beta homolog (Drosophila) 0.044
prmt5 protein arginine methyltransferase 5 0.044
fanca Fanconi anemia, complementation group A 0.044
cry3 cryptochrome 3 0.043
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.042
ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.041
snrpc small nuclear ribonucleoprotein polypeptide C 0.041
pknox1.2 pbx/knotted 1 homeobox 1.2 0.041
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dik diskette 0.995
Sir2 CG5216 gene product from transcript CG5216-RA 0.992
Mad Mothers against dpp 0.991
CG10414 CG10414 gene product from transcript CG10414-RA 0.972
BRWD3 CG31132 gene product from transcript CG31132-RA 0.969
Snr1 Snf5-related 1 0.968
scny scrawny 0.925
wds will die slowly 0.919
Su(var)3-3 Suppressor of variegation 3-3 0.897
Pcaf CG4107 gene product from transcript CG4107-RA 0.894
not non-stop 0.865
trx trithorax 0.850
Atac1 ATAC component 1 0.847
gro groucho 0.834
CG16812 CG16812 gene product from transcript CG16812-RA 0.817
Hcf Host cell factor 0.809
mof males absent on the first 0.797
Fas2 Fasciclin 2 0.785
Caf1 Chromatin assembly factor 1 subunit 0.779
Iswi Imitation SWI 0.777
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.749
hyd hyperplastic discs 0.746
Scm Sex comb on midleg 0.704
Dref DNA replication-related element factor 0.698
CG3363 CG3363 gene product from transcript CG3363-RB 0.691
tws twins 0.686
brm brahma 0.683
mod(mdg4) modifier of mdg4 0.681
Rpd3 CG7471 gene product from transcript CG7471-RA 0.679
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.675
msl-3 male-specific lethal 3 0.660
Pp1-87B Protein phosphatase 1 at 87B 0.655
argos CG4531 gene product from transcript CG4531-RA 0.638
cg combgap 0.614
p53 CG33336 gene product from transcript CG33336-RB 0.603
cdc2 CG5363 gene product from transcript CG5363-RA 0.583
hth homothorax 0.554
Pka-C1 cAMP-dependent protein kinase 1 0.546
His2Av Histone H2A variant 0.543
lwr lesswright 0.537
Rga Regena 0.536
brat brain tumor 0.526
sti sticky 0.508
Su(z)2 Suppressor of zeste 2 0.489
Mocs2 Molybdopterin synthase 2 0.488
Rm62 CG10279 gene product from transcript CG10279-RD 0.488
Utx CG5640 gene product from transcript CG5640-RD 0.479
ecd ecdysoneless 0.476
dm diminutive 0.474
jumu jumeau 0.473
nkd naked cuticle 0.462
Pc Polycomb 0.453
Saf6 SAGA factor-like TAF6 0.452
Gap1 GTPase-activating protein 1 0.452
Su(var)2-10 Suppressor of variegation 2-10 0.443
asp abnormal spindle 0.438
pan pangolin 0.434
ed echinoid 0.434
CTCF CG8591 gene product from transcript CG8591-RA 0.428
ph-d polyhomeotic distal 0.426
Akt1 CG4006 gene product from transcript CG4006-RA 0.423
D12 CG13400 gene product from transcript CG13400-RA 0.417
Top1 Topoisomerase 1 0.405
wapl wings apart-like 0.394
dnc dunce 0.392
dom domino 0.391
fzy fizzy 0.391
ash2 absent, small, or homeotic discs 2 0.356
Su(H) Suppressor of Hairless 0.327
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.311
sxc super sex combs 0.303
slmb supernumerary limbs 0.300
mle maleless 0.297
Sgf29 CG30390 gene product from transcript CG30390-RA 0.290
CycD Cyclin D 0.287
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.285
pie pineapple eye 0.283
U2af38 U2 small nuclear riboprotein auxiliary factor 38 0.280
r2d2 CG7138 gene product from transcript CG7138-RB 0.279
pr-set7 CG3307 gene product from transcript CG3307-RC 0.277
mxc multi sex combs 0.270
CycT Cyclin T 0.268
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.251
Bre1 CG10542 gene product from transcript CG10542-RA 0.249
egg eggless 0.248
e(y)1 enhancer of yellow 1 0.244
BubR1 Bub1-related kinase 0.242
Ras85D Ras oncogene at 85D 0.239
mi minus 0.235
ebi CG4063 gene product from transcript CG4063-RA 0.235
CycK Cyclin K 0.233
Bap170 Brahma associated protein 170kD 0.232
koi klaroid 0.231
CG13689 CG13689 gene product from transcript CG13689-RA 0.229
CstF-50 CG2261 gene product from transcript CG2261-RA 0.227
Cul-4 Cullin-4 0.227
Rpb4 CG33520 gene product from transcript CG33520-RF 0.225
SMC2 CG10212 gene product from transcript CG10212-RA 0.222
nej nejire 0.221
Rae1 CG9862 gene product from transcript CG9862-RA 0.219
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
WDR5 WD repeat domain 5 1.000
SIN3A SIN3 homolog A, transcription regulator (yeast) 1.000
HDAC1 histone deacetylase 1 1.000
TP53 tumor protein p53 1.000
BRCA1 breast cancer 1, early onset 1.000
HDAC2 histone deacetylase 2 1.000
RB1 retinoblastoma 1 1.000
TRRAP transformation/transcription domain-associated protein 1.000
KDM1A lysine (K)-specific demethylase 1A 1.000
RBBP4 retinoblastoma binding protein 4 1.000
CREBBP CREB binding protein 1.000
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.000
HIST1H3B histone cluster 1, H3b 1.000
DAXX death-domain associated protein 1.000
NCOR1 nuclear receptor corepressor 1 0.999
SIRT1 sirtuin 1 0.999
ACTL6A actin-like 6A 0.999
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.999
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.999
YY1 YY1 transcription factor 0.999
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.998
H2AFX H2A histone family, member X 0.998
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.996
C20orf20 chromosome 20 open reading frame 20 0.995
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.995
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.995
EED embryonic ectoderm development 0.995
HIST2H3C histone cluster 2, H3c 0.994
JUN jun proto-oncogene 0.994
KAT2B K(lysine) acetyltransferase 2B 0.993
H3F3C H3 histone, family 3C 0.993
KAT2A K(lysine) acetyltransferase 2A 0.992
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.991
MYST1 MYST histone acetyltransferase 1 0.989
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.987
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.987
EP300 E1A binding protein p300 0.986
RBBP7 retinoblastoma binding protein 7 0.986
HCFC1 host cell factor C1 (VP16-accessory protein) 0.982
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.981
AURKB aurora kinase B 0.979
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.979
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.979
HIST1H4F histone cluster 1, H4f 0.979
AR androgen receptor 0.979
TBP TATA box binding protein 0.974
CHD8 chromodomain helicase DNA binding protein 8 0.974
USP22 ubiquitin specific peptidase 22 0.973
BCOR BCL6 corepressor 0.971
TRIM28 tripartite motif containing 28 0.970
RUVBL1 RuvB-like 1 (E. coli) 0.966
TAL1 T-cell acute lymphocytic leukemia 1 0.964
MTA1 metastasis associated 1 0.962
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.959
SUZ12 suppressor of zeste 12 homolog (Drosophila) 0.958
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.958
TSC22D1 TSC22 domain family, member 1 0.957
NCOA6 nuclear receptor coactivator 6 0.955
INCENP inner centromere protein antigens 135/155kDa 0.953
ESR1 estrogen receptor 1 0.952
TP53BP1 tumor protein p53 binding protein 1 0.951
PML promyelocytic leukemia 0.950
NBN nibrin 0.946
RNF5 ring finger protein 5 0.942
TADA3 transcriptional adaptor 3 0.941
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.941
KAT5 K(lysine) acetyltransferase 5 0.940
PARP1 poly (ADP-ribose) polymerase 1 0.940
CXXC1 CXXC finger protein 1 0.940
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.937
DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.928
MEN1 multiple endocrine neoplasia I 0.926
RNF2 ring finger protein 2 0.926
NCOR2 nuclear receptor corepressor 2 0.925
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.923
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.914
CBX5 chromobox homolog 5 0.914
HIST2H2AC histone cluster 2, H2ac 0.912
CREB1 cAMP responsive element binding protein 1 0.910
HTT huntingtin 0.905
INO80 INO80 homolog (S. cerevisiae) 0.899
NCOA2 nuclear receptor coactivator 2 0.896
HIST1H3A histone cluster 1, H3a 0.894
ATF2 activating transcription factor 2 0.892
RPAP3 RNA polymerase II associated protein 3 0.888
CHD4 chromodomain helicase DNA binding protein 4 0.878
NCF1 neutrophil cytosolic factor 1 0.875
RUVBL2 RuvB-like 2 (E. coli) 0.871
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.847
SMAD3 SMAD family member 3 0.841
DUSP1 dual specificity phosphatase 1 0.841
ARRB1 arrestin, beta 1 0.837
CDK2 cyclin-dependent kinase 2 0.837
GSK3B glycogen synthase kinase 3 beta 0.835
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.834
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.826
NIPBL Nipped-B homolog (Drosophila) 0.816
RBBP5 retinoblastoma binding protein 5 0.802
MED15 mediator complex subunit 15 0.789
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.788
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Rnf2 ring finger protein 2 1.000
Rybp RING1 and YY1 binding protein 1.000
Pou5f1 POU domain, class 5, transcription factor 1 1.000
Arid1a AT rich interactive domain 1A (SWI-like) 0.999
Kat2a K(lysine) acetyltransferase 2A 0.999
Sin3a transcriptional regulator, SIN3A (yeast) 0.999
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.997
Crebbp CREB binding protein 0.997
Wdr5 WD repeat domain 5 0.996
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.994
Kdm1a lysine (K)-specific demethylase 1A 0.992
Hdac1 histone deacetylase 1 0.991
Trrap transformation/transcription domain-associated protein 0.991
Kdm2b lysine (K)-specific demethylase 2B 0.990
Per2 period homolog 2 (Drosophila) 0.989
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.977
Tcf3 transcription factor 3 0.969
Rbbp4 retinoblastoma binding protein 4 0.966
Trp53 transformation related protein 53 0.963
Nanog Nanog homeobox 0.957
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.954
Clock circadian locomotor output cycles kaput 0.950
Pcgf2 polycomb group ring finger 2 0.943
Ep400 E1A binding protein p400 0.938
Mdm2 transformed mouse 3T3 cell double minute 2 0.936
Mga MAX gene associated 0.933
Runx1 runt related transcription factor 1 0.932
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.925
Hdac5 histone deacetylase 5 0.925
Cry2 cryptochrome 2 (photolyase-like) 0.920
Mef2d myocyte enhancer factor 2D 0.909
Tal1 T-cell acute lymphocytic leukemia 1 0.895
Bcor BCL6 interacting corepressor 0.885
Chd4 chromodomain helicase DNA binding protein 4 0.885
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.857
Jarid2 jumonji, AT rich interactive domain 2 0.845
Smc3 structural maintenace of chromosomes 3 0.838
Sox2 SRY-box containing gene 2 0.837
Mta1 metastasis associated 1 0.834
Esrrb estrogen related receptor, beta 0.828
Atm ataxia telangiectasia mutated homolog (human) 0.816
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.813
Dnmt3a DNA methyltransferase 3A 0.807
Foxp1 forkhead box P1 0.798
Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.794
Dmap1 DNA methyltransferase 1-associated protein 1 0.789
Myod1 myogenic differentiation 1 0.784
Ncor1 nuclear receptor co-repressor 1 0.780
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.762
Arid1b AT rich interactive domain 1B (SWI-like) 0.759
Ep300 E1A binding protein p300 0.753
Cry1 cryptochrome 1 (photolyase-like) 0.742
Arid4b AT rich interactive domain 4B (RBP1-like) 0.737
Traf6 TNF receptor-associated factor 6 0.727
Zfp292 zinc finger protein 292 0.725
Msx1 homeobox, msh-like 1 0.723
Cdk4 cyclin-dependent kinase 4 0.721
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.716
Polr2a polymerase (RNA) II (DNA directed) polypeptide A 0.711
Rbbp7 retinoblastoma binding protein 7 0.707
Men1 multiple endocrine neoplasia 1 0.691
Hdac2 histone deacetylase 2 0.687
Jun Jun oncogene 0.680
Csnk2a1 casein kinase 2, alpha 1 polypeptide 0.671
Pax3 paired box gene 3 0.671
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.660
Rbbp5 retinoblastoma binding protein 5 0.658
Tada2a transcriptional adaptor 2A 0.657
Phc2 polyhomeotic-like 2 (Drosophila) 0.655
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.655
Trim28 tripartite motif-containing 28 0.646
Ikzf1 IKAROS family zinc finger 1 0.641
Gli2 GLI-Kruppel family member GLI2 0.638
Kat5 K(lysine) acetyltransferase 5 0.637
Arid2 AT rich interactive domain 2 (ARID, RFX-like) 0.622
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.598
Tcfcp2l1 transcription factor CP2-like 1 0.589
Tcf12 transcription factor 12 0.589
Ldb3 LIM domain binding 3 0.588
Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.574
Setdb1 SET domain, bifurcated 1 0.570
Socs1 suppressor of cytokine signaling 1 0.566
Zfp592 zinc finger protein 592 0.566
Gata1 GATA binding protein 1 0.565
Brd4 bromodomain containing 4 0.565
Yy1 YY1 transcription factor 0.564
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.555
Stk38 serine/threonine kinase 38 0.552
Neurod1 neurogenic differentiation 1 0.551
Sp1 trans-acting transcription factor 1 0.530
Atg12 autophagy-related 12 (yeast) 0.530
Stat3 signal transducer and activator of transcription 3 0.525
Skil SKI-like 0.523
Per1 period homolog 1 (Drosophila) 0.521
Mbtd1 mbt domain containing 1 0.517
Mll2 myeloid/lymphoid or mixed-lineage leukemia 2 0.510
Dcaf7 DDB1 and CUL4 associated factor 7 0.507
Numa1 nuclear mitotic apparatus protein 1 0.506
Sox4 SRY-box containing gene 4 0.501
Pias1 protein inhibitor of activated STAT 1 0.501
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Mcm7 minichromosome maintenance complex component 7 0.082
Brd4 bromodomain containing 4 0.077
Phf12 PHD finger protein 12 0.062
Srrm2 serine/arginine repetitive matrix 2 0.059
Actb actin, beta 0.049
Arid4a AT rich interactive domain 4A (Rbp1 like) 0.048
Casp2 caspase 2 0.047
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.047
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.044
LOC688211 hypothetical protein LOC688211 0.043
Map2k7 mitogen activated protein kinase kinase 7 0.041
Falz fetal Alzheimer antigen 0.041
Dcaf15 DDB1 and CUL4 associated factor 15 0.039
Racgap1 Rac GTPase-activating protein 1 0.037
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.037
Ehmt1 euchromatic histone-lysine N-methyltransferase 1 0.033
Tuba1c tubulin, alpha 1C 0.033
Med1 mediator complex subunit 1 0.030
Myst3 MYST histone acetyltransferase (monocytic leukemia) 3 0.027
Usp7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.026
Acin1 apoptotic chromatin condensation inducer 1 0.025
LOC682469 similar to jumonji domain containing 1B 0.024
Zfand6 zinc finger, AN1-type domain 6 0.023
Rbbp7 retinoblastoma binding protein 7 0.023
Klf9 Kruppel-like factor 9 0.023
Srrm1 serine/arginine repetitive matrix 1 0.023
Clns1a chloride channel, nucleotide-sensitive, 1A 0.022
Wdr26 WD repeat domain 26 0.021
Safb scaffold attachment factor B 0.021
Nup88 nucleoporin 88 0.020
Stip1 stress-induced phosphoprotein 1 0.020
Luc7l2 LUC7-like 2 (S. cerevisiae) 0.020
Sfrs3 splicing factor, arginine/serine-rich 3 0.019
Timeless timeless homolog (Drosophila) 0.019
Snrnp70 small nuclear ribonucleoprotein 70 (U1) 0.019
Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 0.019
Scarb1 scavenger receptor class B, member 1 0.018
Traf4af1 TRAF4 associated factor 1 0.018
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.018
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.017
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.017
LOC687711 similar to small nuclear ribonucleoprotein D3 0.017
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.017
Fam193a family with sequence similarity 193, member A 0.017
Brd3 bromodomain containing 3 0.017
Eed embryonic ectoderm development 0.016
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.016
Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.016
Ubtf upstream binding transcription factor, RNA polymerase I 0.016
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.016
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.016
Kdm2a lysine (K)-specific demethylase 2A 0.015
LOC690911 similar to Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein) 0.015
Tcfe2a transcription factor E2a 0.015
Top2a topoisomerase (DNA) II alpha 0.015
Psma4 proteasome (prosome, macropain) subunit, alpha type 4 0.015
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.015
Cdc2l6 cell division cycle 2-like 6 (CDK8-like) 0.015
Ldb1 LIM domain binding 1 0.015
Appbp2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.015
Pcna proliferating cell nuclear antigen 0.014
Phax phosphorylated adaptor for RNA export 0.014
Hcfc1 host cell factor C1 0.014
Cebpg CCAAT/enhancer binding protein (C/EBP), gamma 0.014
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.014
Sfrs4 splicing factor, arginine/serine-rich 4 0.014
Chd1 chromodomain helicase DNA binding protein 1 0.014
Khsrp KH-type splicing regulatory protein 0.014
Klf2 Kruppel-like factor 2 (lung) 0.014
Sart3 squamous cell carcinoma antigen recognized by T-cells 3 0.014
RGD1311703 similar to sid2057p 0.013
Ubr4 ubiquitin protein ligase E3 component n-recognin 4 0.013
Srpk1 SFRS protein kinase 1 0.013
Hist1h1a histone cluster 1, H1a 0.013
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.013
Znf692 zinc finger protein 692 0.013
Raly RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) 0.013
Suv420h1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.013
Bat1 HLA-B associated transcript 1 0.012
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.012
Nfat5 nuclear factor of activated T-cells 5 0.012
Cdca8 cell division cycle associated 8 0.012
Wiz widely-interspaced zinc finger motifs 0.012
Ythdc1 YTH domain containing 1 0.012
Tnrc6b trinucleotide repeat containing 6B 0.012
Arih2 ariadne homolog 2 (Drosophila) 0.012
Abcc5 ATP-binding cassette, subfamily C (CFTR/MRP), member 5 0.012
Cand1 cullin-associated and neddylation-dissociated 1 0.012
Cyth2 cytohesin 2 0.012
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.012
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.012
Jak1 Janus kinase 1 0.012
Lbr lamin B receptor 0.012
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform 0.012
Rnf111 ring finger protein 111 0.012
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.012
Sin3a SIN3 homolog A, transcription regulator (yeast) 0.012
Axin1 axin 1 0.012
Per1 period homolog 1 (Drosophila) 0.011
Tnrc6a trinucleotide repeat containing 6a 0.011