The network for 'alpha amino acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

alpha amino acid metabolic process

The chemical reactions and pathways involving an alpha-amino acid.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ARG5,6 Arg5,6p 0.981
ARO2 Aro2p 0.976
SER1 Ser1p 0.938
HIS5 His5p 0.915
SHM2 Shm2p 0.913
HIS4 His4p 0.912
ASN1 Asn1p 0.893
MET6 Met6p 0.890
CPA2 Cpa2p 0.871
ARO1 Aro1p 0.862
KRS1 Krs1p 0.850
ARO8 Aro8p 0.840
ARG1 Arg1p 0.805
ASP3-4 Asp3-4p 0.774
ARG4 Arg4p 0.770
ASP3-3 Asp3-3p 0.744
LEU9 Leu9p 0.738
TRP2 Trp2p 0.735
GCV3 Gcv3p 0.719
ASP3-2 Asp3-2p 0.703
LYS1 Lys1p 0.682
TRP3 Trp3p 0.671
MET13 Met13p 0.666
ARO9 Aro9p 0.637
ARG2 Arg2p 0.632
THR4 Thr4p 0.610
GND1 Gnd1p 0.597
HIS7 His7p 0.591
LSC2 Lsc2p 0.588
ILV1 Ilv1p 0.574
SAM1 Sam1p 0.572
ACS2 Acs2p 0.570
GCV1 Gcv1p 0.564
TRP5 Trp5p 0.555
ASP3-1 Asp3-1p 0.538
FSF1 Fsf1p 0.535
GCV2 Gcv2p 0.530
MET22 Met22p 0.524
ADE17 Ade17p 0.506
MET10 Met10p 0.506
RPC40 Rpc40p 0.478
ARG81 Arg81p 0.472
NIF3 Nif3p 0.424
LYS21 Lys21p 0.421
FMP40 Fmp40p 0.419
LYS12 Lys12p 0.409
ILV3 Ilv3p 0.406
BAT2 Bat2p 0.405
SSM4 Ssm4p 0.399
HOM2 Hom2p 0.399
ADE4 Ade4p 0.395
TAE1 Tae1p 0.389
CAR1 Car1p 0.382
TRP4 Trp4p 0.381
MET14 Met14p 0.364
PDC5 Pdc5p 0.358
ADE12 Ade12p 0.347
HTS1 Hts1p 0.347
MET5 Met5p 0.346
LHP1 Lhp1p 0.345
STR3 Str3p 0.344
LEU4 Leu4p 0.343
GGC1 Ggc1p 0.331
KAP123 Kap123p 0.319
HOM3 Hom3p 0.316
GUS1 Gus1p 0.315
TKL1 Tkl1p 0.306
YOR302W hypothetical protein 0.299
HIS2 His2p 0.294
LYS2 Lys2p 0.293
SAM4 Sam4p 0.284
ADE5,7 Ade5,7p 0.282
PRS4 Prs4p 0.282
MET3 Met3p 0.278
ERV46 Erv46p 0.277
MET16 Met16p 0.270
SPE3 Spe3p 0.267
ERG13 Erg13p 0.266
ARG7 Arg7p 0.263
ALD4 Ald4p 0.252
LAT1 Lat1p 0.251
CYS3 Cys3p 0.244
DUG1 Dug1p 0.239
HSP60 Hsp60p 0.237
UGA3 Uga3p 0.236
YLR057W hypothetical protein 0.233
YMR321C hypothetical protein 0.221
HOM6 Hom6p 0.220
HIS1 His1p 0.218
MCH4 Mch4p 0.217
ORT1 Ort1p 0.217
ARO3 Aro3p 0.214
IDP1 Idp1p 0.209
AAT2 Aat2p 0.209
YJR111C hypothetical protein 0.203
NRM1 Nrm1p 0.200
RMD6 Rmd6p 0.198
FOL2 Fol2p 0.198
LEU2 Leu2p 0.198
CIN2 Cin2p 0.196
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
hsp-3 Protein HSP-3 0.407
CELE_R02D3.1 Protein R02D3.1 0.156
cat-1 Protein CAT-1 0.088
F55G1.5 Protein F55G1.5 0.087
CELE_ZK1307.1 Protein ZK1307.1 0.076
acs-5 Protein ACS-5 0.072
fah-1 Protein FAH-1 0.056
cbl-1 Protein CBL-1 0.050
dpyd-1 Protein DPYD-1 0.048
CELE_Y51H4A.7 Protein Y51H4A.7 0.044
nhr-32 Protein NHR-32 0.044
hpd-1 Protein HPD-1 0.041
egl-3 Protein EGL-3 0.040
ugt-58 Protein UGT-58 0.040
sams-1 Protein SAMS-1 0.038
idh-2 Protein IDH-2 0.034
aldo-1 Protein ALDO-1 0.033
CELE_T05E11.3 Protein T05E11.3 0.030
K07E3.4 Protein K07E3.4 0.030
bas-1 Protein BAS-1 0.030
T14G8.3 Protein T14G8.3 0.029
act-3 Protein ACT-3 0.028
cysl-2 Protein CYSL-2 0.026
mtrr-1 Protein MTRR-1 0.025
haly-1 Protein HALY-1 0.024
calu-1 Protein CALU-1 0.024
pcca-1 Protein PCCA-1 0.024
CELE_T08H10.1 Protein T08H10.1 0.022
C48B4.8 Protein C48B4.8 0.022
trap-2 Protein TRAP-2 0.020
hgo-1 Protein HGO-1 0.020
lrp-1 Protein LRP-1 0.019
F17A9.4 Protein F17A9.4 0.019
fmo-4 Protein FMO-4 0.018
got-1.2 Protein GOT-1.2 0.018
C16A3.10 Protein C16A3.10 0.018
apm-1 Protein APM-1 0.017
gpd-3 Protein GPD-3 0.017
vha-5 Protein VHA-5 0.017
nit-1 Protein NIT-1 0.017
CELE_Y111B2A.2 Protein Y111B2A.2 0.016
amt-4 Protein AMT-4 0.016
sams-4 Protein SAMS-4 0.015
Y71G12B.6 Protein Y71G12B.6 0.015
aco-1 Protein ACO-1 0.015
iff-2 Protein IFF-2 0.015
K12C11.1 Protein K12C11.1 0.014
R08E5.3 Protein R08E5.3 0.014
hsp-4 Protein HSP-4 0.014
C34B2.6 Protein C34B2.6 0.014
lmp-1 Protein LMP-1 0.013
alh-3 Protein ALH-3 0.013
lite-1 Protein LITE-1 0.013
hke-4.2 Protein HKE-4.2 0.013
T06D8.1 Protein T06D8.1 0.013
clh-1 Protein CLH-1 0.013
lpd-3 Protein LPD-3 0.013
pmt-2 Protein PMT-2 0.012
ksr-1 Protein KSR-1 0.011
M153.1 Protein M153.1 0.011
spe-5 Protein SPE-5 0.011
tag-320 Protein TAG-320 0.011
C44C1.5 Protein C44C1.5 0.010
fbp-1 Protein FBP-1 0.010
pck-1 Protein PCK-1 0.010
asg-1 Protein ASG-1 0.010
aldo-2 Protein ALDO-2 0.010
T01E8.1 Protein T01E8.1 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ghrb growth hormone receptor b 0.850
aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.715
mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 0.665
gyg1 glycogenin 1 0.606
aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.583
glud1a glutamate dehydrogenase 1a 0.578
sec23a Sec23 homolog A (S. cerevisiae) 0.549
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.498
ivd isovaleryl Coenzyme A dehydrogenase 0.450
pah phenylalanine hydroxylase 0.449
aldob aldolase b, fructose-bisphosphate 0.446
otc ornithine carbamoyltransferase 0.382
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.360
ednrb1 endothelin receptor B 0.356
tyr tyrosinase 0.353
tyms thymidylate synthase 0.340
mitfa microphthalmia-associated transcription factor a 0.339
cpa2 carboxypeptidase A2 (pancreatic) 0.320
kita kit receptor a 0.312
zgc:66382 zgc:66382 0.310
fbp1b fructose-1,6-bisphosphatase 1b 0.306
mdh1a malate dehydrogenase 1a, NAD (soluble) 0.304
eif4ebp3l eukaryotic translation initiation factor 4E binding protein 3, like 0.303
ahcy S-adenosylhomocysteine hydrolase 0.300
lrrc17 leucine rich repeat containing 17 0.287
nos1 nitric oxide synthase 1 (neuronal) 0.282
ghra growth hormone receptor a 0.279
gpia glucose phosphate isomerase a 0.274
p4ha1b prolyl 4-hydroxylase, alpha polypeptide I b 0.271
wu:fc57f07 wu:fc57f07 0.267
mat1a methionine adenosyltransferase I, alpha 0.250
prdx2 peroxiredoxin 2 0.244
arrdc1a arrestin domain containing 1a 0.234
brd2b bromodomain containing 2b 0.232
optc opticin 0.227
pmela premelanosome protein a 0.226
dhfr dihydrofolate reductase 0.200
mibp2 muscle-specific beta 1 integrin binding protein 2 0.194
sult6b1 sulfotransferase family, cytosolic, 6b, member 1 0.192
pcbd1 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 0.188
sst1.1 somatostatin 1, tandem duplicate 1 0.186
cbsb cystathionine-beta-synthase b 0.183
si:ch211-284e13.2 si:ch211-284e13.2 0.180
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.179
gsnb gelsolin b 0.177
aox3 aldehyde oxidase 3 0.176
ghrl ghrelin/obestatin preprohormone 0.163
aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.163
sod2 superoxide dismutase 2, mitochondrial 0.160
sb:cb930 sb:cb930 0.151
tkt transketolase 0.145
mat2a methionine adenosyltransferase II, alpha 0.143
capn2b calpain 2, (m/II) large subunit b 0.140
mpzl2 myelin protein zero-like 2 0.139
gad2 glutamate decarboxylase 2 0.139
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.138
angptl2 angiopoietin-like 2 0.134
vsx2 visual system homeobox 2 0.132
cldn7b claudin 7b 0.130
tyrp1 tyrosinase-related protein 1 0.130
si:ch211-154o6.6 si:ch211-154o6.6 0.130
wu:fb63c04 wu:fb63c04 0.129
txnrd1 thioredoxin reductase 1 0.127
acat1 acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) 0.119
ppp1r3ca protein phosphatase 1, regulatory (inhibitor) subunit 3Ca 0.117
cldni claudin i 0.117
abcd3a ATP-binding cassette, sub-family D (ALD), member 3a 0.115
mt2 metallothionein 2 0.115
dldh dihydrolipoamide dehydrogenase 0.115
ccng1 cyclin G1 0.114
slit1a slit homolog 1a (Drosophila) 0.113
tob1a transducer of ERBB2, 1a 0.113
si:ch73-13b6.3 si:ch73-13b6.3 0.111
adh5 alcohol dehydrogenase 5 0.109
gabbr1a gamma-aminobutyric acid (GABA) B receptor, 1a 0.104
hif1an hypoxia-inducible factor 1, alpha subunit inhibitor 0.104
vsx1 visual system homeobox 1 homolog, chx10-like 0.104
LOC799612 prolactin 2 0.102
atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.100
paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.100
tomm34 translocase of outer mitochondrial membrane 34 0.096
wu:fb39a06 wu:fb39a06 0.096
nos2b nitric oxide synthase 2b, inducible 0.095
zgc:92090 zgc:92090 0.095
zgc:86841 zgc:86841 0.093
st8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.092
zgc:64133 zgc:64133 0.092
aldoaa aldolase a, fructose-bisphosphate, a 0.092
nt5dc2 5'-nucleotidase domain containing 2 0.092
gdf9 growth differentiation factor 9 0.091
idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.091
acy3.2 aspartoacylase (aminocyclase) 3.2 0.090
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.090
hgd homogentisate 1,2-dioxygenase 0.089
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.088
dhtkd1 dehydrogenase E1 and transketolase domain containing 1 0.088
psat1 phosphoserine aminotransferase 1 0.088
rrm2b ribonucleotide reductase M2 b 0.088
sec13 SEC13 homolog (S. cerevisiae) 0.086
gamt guanidinoacetate N-methyltransferase 0.084
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CG8036 CG8036 gene product from transcript CG8036-RB 0.386
CG10932 CG10932 gene product from transcript CG10932-RA 0.340
Hex-C Hexokinase C 0.295
CG6415 CG6415 gene product from transcript CG6415-RA 0.239
Adh Alcohol dehydrogenase 0.232
CG11786 CG11786 gene product from transcript CG11786-RB 0.194
Acon Aconitase 0.172
Oat Ornithine aminotransferase precursor 0.171
CG7920 CG7920 gene product from transcript CG7920-RA 0.122
CG3902 CG3902 gene product from transcript CG3902-RA 0.121
Gdh Glutamate dehydrogenase 0.114
ade5 CG3989 gene product from transcript CG3989-RA 0.113
CG10512 CG10512 gene product from transcript CG10512-RA 0.096
CG17325 CG17325 gene product from transcript CG17325-RA 0.091
kar karmoisin 0.083
CG5599 CG5599 gene product from transcript CG5599-RA 0.080
Hsp60 Heat shock protein 60 0.078
Ahcy13 Adenosylhomocysteinase at 13 0.078
CG6361 CG6361 gene product from transcript CG6361-RA 0.078
CG12766 CG12766 gene product from transcript CG12766-RA 0.074
ade3 adenosine 3 0.071
CG10570 CG10570 gene product from transcript CG10570-RA 0.068
v vermilion 0.068
Hmgs HMG Coenzyme A synthase 0.068
Sodh-1 Sorbitol dehydrogenase 1 0.067
pug pugilist 0.065
ry rosy 0.065
CG14113 CG14113 gene product from transcript CG14113-RA 0.064
CG8446 CG8446 gene product from transcript CG8446-RC 0.064
CG18003 CG18003 gene product from transcript CG18003-RA 0.064
hgo homogentisate 1,2-dioxygenase 0.061
CG15478 CG15478 gene product from transcript CG15478-RA 0.060
Hn Henna 0.057
cad caudal 0.055
ltd lightoid 0.055
CG1600 CG1600 gene product from transcript CG1600-RA 0.050
CG9649 CG9649 gene product from transcript CG9649-RA 0.050
Vha14 Vacuolar H[+] ATPase 14kD subunit 0.050
Aldh Aldehyde dehydrogenase 0.050
CG3267 CG3267 gene product from transcript CG3267-RA 0.049
CG9396 CG9396 gene product from transcript CG9396-RA 0.048
Got2 Glutamate oxaloacetate transaminase 2 0.048
CG2852 CG2852 gene product from transcript CG2852-RA 0.047
kkv krotzkopf verkehrt 0.046
CG16704 CG16704 gene product from transcript CG16704-RA 0.045
Pgm Phosphogluconate mutase 0.044
yellow-f2 CG8063 gene product from transcript CG8063-RA 0.043
CG1628 CG1628 gene product from transcript CG1628-RB 0.042
sev sevenless 0.041
CAH1 Carbonic anhydrase 1 0.041
l(1)G0255 lethal (1) G0255 0.041
CG3597 CG3597 gene product from transcript CG3597-RA 0.040
th thread 0.039
tll tailless 0.039
CG9897 CG9897 gene product from transcript CG9897-RA 0.039
CG15093 CG15093 gene product from transcript CG15093-RB 0.039
CG11089 CG11089 gene product from transcript CG11089-RD 0.037
CG5044 CG5044 gene product from transcript CG5044-RB 0.036
CG16733 CG16733 gene product from transcript CG16733-RA 0.036
CG9940 CG9940 gene product from transcript CG9940-RB 0.035
CD98hc CD98 heavy chain 0.035
Picot CG8098 gene product from transcript CG8098-RA 0.035
n-syb n-synaptobrevin 0.034
CG5288 CG5288 gene product from transcript CG5288-RA 0.034
CG1640 CG1640 gene product from transcript CG1640-RB 0.034
Muc91C Mucin 91C 0.033
CG6428 CG6428 gene product from transcript CG6428-RA 0.033
CG3699 CG3699 gene product from transcript CG3699-RA 0.033
Ance-5 CG10142 gene product from transcript CG10142-RA 0.032
ERR estrogen-related receptor 0.032
inx2 innexin 2 0.031
CG9547 CG9547 gene product from transcript CG9547-RA 0.031
serp serpentine 0.031
CG9925 CG9925 gene product from transcript CG9925-RA 0.030
ssp5 short spindle 5 0.029
CG4797 CG4797 gene product from transcript CG4797-RA 0.029
CG6020 CG6020 gene product from transcript CG6020-RA 0.028
CG12558 CG12558 gene product from transcript CG12558-RA 0.028
smp-30 Senescence marker protein-30 0.027
CG3239 CG3239 gene product from transcript CG3239-RB 0.027
Pld Phospholipase D 0.027
CG11255 CG11255 gene product from transcript CG11255-RA 0.027
CG6455 CG6455 gene product from transcript CG6455-RC 0.026
CG10621 CG10621 gene product from transcript CG10621-RA 0.026
CG3982 CG3982 gene product from transcript CG3982-RA 0.025
Lsd-1 Lipid storage droplet-1 0.025
Aldh-III Aldehyde dehydrogenase type III 0.025
Dip-B Dipeptidase B 0.025
Vha100-2 CG18617 gene product from transcript CG18617-RB 0.025
CG3714 CG3714 gene product from transcript CG3714-RC 0.024
CG10184 CG10184 gene product from transcript CG10184-RA 0.024
CG10992 CG10992 gene product from transcript CG10992-RA 0.024
l(3)02640 lethal (3) 02640 0.024
CG6969 CG6969 gene product from transcript CG6969-RA 0.024
e ebony 0.024
Ance-4 CG8196 gene product from transcript CG8196-RA 0.024
CG11380 CG11380 gene product from transcript CG11380-RA 0.023
HmgZ HMG protein Z 0.023
cn cinnabar 0.023
CG3999 CG3999 gene product from transcript CG3999-RA 0.023
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YARS tyrosyl-tRNA synthetase 0.976
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.956
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.874
GARS glycyl-tRNA synthetase 0.843
AARS alanyl-tRNA synthetase 0.831
IARS isoleucyl-tRNA synthetase 0.818
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.812
PSAT1 phosphoserine aminotransferase 1 0.805
MED25 mediator complex subunit 25 0.800
GGT1 gamma-glutamyltransferase 1 0.729
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.728
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.668
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.616
ERO1L ERO1-like (S. cerevisiae) 0.504
RARA retinoic acid receptor, alpha 0.457
XPOT exportin, tRNA (nuclear export receptor for tRNAs) 0.450
MARS methionyl-tRNA synthetase 0.425
GGTLC1 gamma-glutamyltransferase light chain 1 0.419
SPOP speckle-type POZ protein 0.391
PHGDH phosphoglycerate dehydrogenase 0.362
NOSTRIN nitric oxide synthase trafficker 0.358
PDIA4 protein disulfide isomerase family A, member 4 0.291
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.275
NRIP1 nuclear receptor interacting protein 1 0.273
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.273
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.270
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.259
INSR insulin receptor 0.250
PGK1 phosphoglycerate kinase 1 0.240
PKM2 pyruvate kinase, muscle 0.232
PDZD11 PDZ domain containing 11 0.229
TUBGCP4 tubulin, gamma complex associated protein 4 0.226
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.222
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.216
GCLC glutamate-cysteine ligase, catalytic subunit 0.209
PDIA3 protein disulfide isomerase family A, member 3 0.199
MAP2K5 mitogen-activated protein kinase kinase 5 0.194
HADH hydroxyacyl-CoA dehydrogenase 0.179
CTPS CTP synthase 0.178
VAC14 Vac14 homolog (S. cerevisiae) 0.172
FAM46A family with sequence similarity 46, member A 0.171
GCLM glutamate-cysteine ligase, modifier subunit 0.165
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.133
TRIB3 tribbles homolog 3 (Drosophila) 0.131
SARS seryl-tRNA synthetase 0.131
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.129
GGT2 gamma-glutamyltransferase 2 0.124
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.124
ENO1 enolase 1, (alpha) 0.120
PRDX1 peroxiredoxin 1 0.119
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.117
TARS threonyl-tRNA synthetase 0.113
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.112
ALDOA aldolase A, fructose-bisphosphate 0.111
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.110
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.105
CARS cysteinyl-tRNA synthetase 0.102
RAB10 RAB10, member RAS oncogene family 0.102
MME membrane metallo-endopeptidase 0.100
PTPRB protein tyrosine phosphatase, receptor type, B 0.100
PROX1 prospero homeobox 1 0.093
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.093
GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.093
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.093
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.091
PCNA proliferating cell nuclear antigen 0.086
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.086
LDHA lactate dehydrogenase A 0.086
TMEM97 transmembrane protein 97 0.084
NCOA1 nuclear receptor coactivator 1 0.082
TJP2 tight junction protein 2 (zona occludens 2) 0.080
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.077
ARNT aryl hydrocarbon receptor nuclear translocator 0.075
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.075
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.075
SOD1 superoxide dismutase 1, soluble 0.072
UCK2 uridine-cytidine kinase 2 0.071
GCDH glutaryl-CoA dehydrogenase 0.071
KANK2 KN motif and ankyrin repeat domains 2 0.070
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.070
HM13 histocompatibility (minor) 13 0.068
PYCR1 pyrroline-5-carboxylate reductase 1 0.067
C21orf33 chromosome 21 open reading frame 33 0.067
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.067
EPT1 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) 0.067
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.065
CA5A carbonic anhydrase VA, mitochondrial 0.065
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.065
TJP1 tight junction protein 1 (zona occludens 1) 0.064
MTA1 metastasis associated 1 0.063
GJA1 gap junction protein, alpha 1, 43kDa 0.063
NARS asparaginyl-tRNA synthetase 0.062
IL2RB interleukin 2 receptor, beta 0.061
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.061
NR1I3 nuclear receptor subfamily 1, group I, member 3 0.059
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.058
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.058
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 0.057
CAV1 caveolin 1, caveolae protein, 22kDa 0.057
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.056
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.991
Lep leptin 0.985
Nos1 nitric oxide synthase 1, neuronal 0.984
Esr1 estrogen receptor 1 (alpha) 0.980
Ptgs2 prostaglandin-endoperoxide synthase 2 0.969
Nos3 nitric oxide synthase 3, endothelial cell 0.927
Vegfa vascular endothelial growth factor A 0.860
Stat5a signal transducer and activator of transcription 5A 0.817
Stat5b signal transducer and activator of transcription 5B 0.765
Prlr prolactin receptor 0.765
Ar androgen receptor 0.686
Sardh sarcosine dehydrogenase 0.680
Il10 interleukin 10 0.679
Hif1a hypoxia inducible factor 1, alpha subunit 0.671
Stat3 signal transducer and activator of transcription 3 0.670
Ghr growth hormone receptor 0.666
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.656
Epas1 endothelial PAS domain protein 1 0.649
Mmp9 matrix metallopeptidase 9 0.627
Cbs cystathionine beta-synthase 0.625
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.622
Pparg peroxisome proliferator activated receptor gamma 0.607
Tgfb1 transforming growth factor, beta 1 0.591
Hnf4a hepatic nuclear factor 4, alpha 0.588
Insr insulin receptor 0.587
Cav1 caveolin 1, caveolae protein 0.565
Irf9 interferon regulatory factor 9 0.563
Kit kit oncogene 0.494
Adam17 a disintegrin and metallopeptidase domain 17 0.400
Dmgdh dimethylglycine dehydrogenase precursor 0.400
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.397
Mccc1 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) 0.381
Col1a1 collagen, type I, alpha 1 0.378
Ran RAN, member RAS oncogene family 0.361
Tlr4 toll-like receptor 4 0.349
Kl klotho 0.339
Il1r1 interleukin 1 receptor, type I 0.330
Calca calcitonin/calcitonin-related polypeptide, alpha 0.314
Mitf microphthalmia-associated transcription factor 0.310
Apc adenomatosis polyposis coli 0.307
Apoe apolipoprotein E 0.305
Gcsh glycine cleavage system protein H (aminomethyl carrier) 0.288
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.286
Lyst lysosomal trafficking regulator 0.278
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.249
Pomc pro-opiomelanocortin-alpha 0.248
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.247
Pmel premelanosome protein 0.240
Ndrg2 N-myc downstream regulated gene 2 0.230
Drd2 dopamine receptor D2 0.230
Pten phosphatase and tensin homolog 0.226
Ivd isovaleryl coenzyme A dehydrogenase 0.224
Ncoa3 nuclear receptor coactivator 3 0.223
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.223
Vdr vitamin D receptor 0.221
a nonagouti 0.219
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.218
Pxmp2 peroxisomal membrane protein 2 0.204
Gnmt glycine N-methyltransferase 0.202
Gjb1 gap junction protein, beta 1 0.198
Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial 0.190
Esr2 estrogen receptor 2 (beta) 0.187
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.187
Gcgr glucagon receptor 0.183
Oca2 oculocutaneous albinism II 0.183
Pgls 6-phosphogluconolactonase 0.183
Tyrp1 tyrosinase-related protein 1 0.182
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.181
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.181
Pipox pipecolic acid oxidase 0.180
Habp2 hyaluronic acid binding protein 2 0.178
Acy1 aminoacylase 1 0.177
Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 0.172
Emx1 empty spiracles homolog 1 (Drosophila) 0.168
Tdo2 tryptophan 2,3-dioxygenase 0.165
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.159
Ak3 adenylate kinase 3 0.159
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.157
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.157
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.156
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.156
Smc1a structural maintenance of chromosomes 1A 0.154
Upp2 uridine phosphorylase 2 0.152
Car5a carbonic anhydrase 5a, mitochondrial 0.150
Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide 0.148
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.145
Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 0.141
Ldlr low density lipoprotein receptor 0.140
Gnrh1 gonadotropin releasing hormone 1 0.140
Ero1l ERO1-like (S. cerevisiae) 0.139
Hgd homogentisate 1, 2-dioxygenase 0.138
Iyd iodotyrosine deiodinase 0.138
Irs2 insulin receptor substrate 2 0.137
Cat catalase 0.137
Mat1a methionine adenosyltransferase I, alpha 0.135
Rho rhodopsin 0.132
Plg plasminogen 0.131
Nars asparaginyl-tRNA synthetase 0.130
Ctnnb1 catenin (cadherin associated protein), beta 1 0.130
Sult1b1 sulfotransferase family 1B, member 1 0.125
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Suclg2 succinate-CoA ligase, GDP-forming, beta subunit 0.932
Sardh sarcosine dehydrogenase 0.866
Ahcy adenosylhomocysteinase 0.836
G6pc glucose-6-phosphatase, catalytic subunit 0.826
Glud1 glutamate dehydrogenase 1 0.824
Pah phenylalanine hydroxylase 0.788
Ass1 argininosuccinate synthetase 1 0.788
Car5a carbonic anhydrase 5a, mitochondrial 0.783
Fbp1 fructose-1,6-bisphosphatase 1 0.765
Dpys dihydropyrimidinase 0.749
Agxt2 alanine-glyoxylate aminotransferase 2 0.721
Adhfe1 alcohol dehydrogenase, iron containing, 1 0.653
Sds serine dehydratase 0.649
Scp2 sterol carrier protein 2 0.598
Tst thiosulfate sulfurtransferase 0.506
Adk adenosine kinase 0.493
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.489
Cbs cystathionine beta synthase 0.485
Aadat aminoadipate aminotransferase 0.423
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.365
Afm afamin 0.353
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.353
Khk ketohexokinase 0.341
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.314
Gcdh glutaryl-Coenzyme A dehydrogenase 0.313
Bmp7 bone morphogenetic protein 7 0.299
Mat1a methionine adenosyltransferase I, alpha 0.284
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.276
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.271
Pcca propionyl-coenzyme A carboxylase, alpha polypeptide 0.265
Mipep mitochondrial intermediate peptidase 0.264
Gclc glutamate-cysteine ligase, catalytic subunit 0.261
Aldh4a1 aldehyde dehydrogenase 4 family, member A1 0.259
Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial 0.254
Rdh2 retinol dehydrogenase 2 0.248
Serpina4 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.246
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.242
Aldob aldolase B, fructose-bisphosphate 0.234
Gnmt glycine N-methyltransferase 0.233
Azgp1 alpha-2-glycoprotein 1, zinc-binding 0.224
Otc ornithine carbamoyltransferase 0.224
Pck1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.220
Orm1 orosomucoid 1 0.211
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.205
Gulo gulonolactone (L-) oxidase 0.202
Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide 0.199
Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 0.196
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.195
Asns asparagine synthetase 0.193
Dio1 deiodinase, iodothyronine, type I 0.192
Pik3c2g phosphoinositide-3-kinase, class 2, gamma polypeptide 0.190
Nipsnap1 nipsnap homolog 1 (C. elegans) 0.187
Ttc36 tetratricopeptide repeat domain 36 0.186
Grhpr glyoxylate reductase/hydroxypyruvate reductase 0.186
Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.181
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.177
Psat1 phosphoserine aminotransferase 1 0.175
Abp10 annexin V-binding protein ABP-10 0.173
Ftcd formiminotransferase cyclodeaminase 0.172
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.172
Isoc1 isochorismatase domain containing 1 0.169
Miox myo-inositol oxygenase 0.167
Dak dihydroxyacetone kinase 2 homolog (S. cerevisiae) 0.165
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.165
Dhfr dihydrofolate reductase 0.164
Mcm6 minichromosome maintenance complex component 6 0.164
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.163
Tdo2 tryptophan 2,3-dioxygenase 0.162
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.162
Ung uracil-DNA glycosylase 0.159
Acot12 acyl-CoA thioesterase 12 0.158
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.157
Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 0.155
F2 coagulation factor II (thrombin) 0.153
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.151
Ahsg alpha-2-HS-glycoprotein 0.151
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.150
Rbp2 retinol binding protein 2, cellular 0.147
Yars tyrosyl-tRNA synthetase 0.146
Phgdh phosphoglycerate dehydrogenase 0.145
Sf3b3 splicing factor 3b, subunit 3 0.144
Hnf4a hepatocyte nuclear factor 4, alpha 0.144
Ppif peptidylprolyl isomerase F 0.142
RGD1305347 similar to RIKEN cDNA 2610528J11 0.142
RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase 0.139
Gys2 glycogen synthase 2 0.139
Hn1l hematological and neurological expressed 1-like 0.138
Hrsp12 heat-responsive protein 12 0.138
Adh1 alcohol dehydrogenase 1 (class I) 0.136
Kynu kynureninase (L-kynurenine hydrolase) 0.136
Pex1 peroxisomal biogenesis factor 1 0.135
RT1-A3 RT1 class I, locus A3 0.133
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.132
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 0.129
Sar1a SAR1 homolog A (S. cerevisiae) 0.126
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.126
Crot carnitine O-octanoyltransferase 0.125
Amacr alpha-methylacyl-CoA racemase 0.125
LOC494499 LOC494499 protein 0.124
Fancc Fanconi anemia, complementation group C 0.124