The network for 'cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SPO21 Spo21p 0.977
ADY3 Ady3p 0.950
GIP1 Gip1p 0.944
RAS2 Ras2p 0.916
SPS22 Sps22p 0.852
MPC54 Mpc54p 0.803
DIT2 Dit2p 0.677
IRA1 Ira1p 0.644
SMK1 Smk1p 0.610
FKS3 Fks3p 0.609
MSN2 Msn2p 0.586
BMH2 Bmh2p 0.572
DIT1 Dit1p 0.571
OSW2 Osw2p 0.522
PCK1 Pck1p 0.505
CRR1 Crr1p 0.503
SPR3 Spr3p 0.470
OSW1 Osw1p 0.447
DTR1 Dtr1p 0.447
AQY2 Aqy2p 0.421
SPO71 Spo71p 0.411
LAP4 Lap4p 0.407
POG1 Pog1p 0.401
SHE4 She4p 0.355
SPS1 Sps1p 0.349
SMA2 Sma2p 0.344
GSC2 Gsc2p 0.329
PDR10 Pdr10p 0.308
ARC35 Arc35p 0.305
NKP2 Nkp2p 0.304
SSP1 Ssp1p 0.294
CAT8 Cat8p 0.293
RIM15 Rim15p 0.290
PPH21 Pph21p 0.288
RGS2 Rgs2p 0.278
RIM101 Rim101p 0.277
CMD1 Cmd1p 0.277
MIG3 Mig3p 0.276
YPT1 Ypt1p 0.272
MIG2 Mig2p 0.270
ECM8 Ecm8p 0.265
AMA1 Ama1p 0.261
SEC9 Sec9p 0.258
DON1 Don1p 0.252
NOP13 Nop13p 0.245
SSO1 Sso1p 0.240
MSO1 Mso1p 0.239
SRL4 Srl4p 0.232
ROX1 Rox1p 0.231
SNC2 Snc2p 0.225
CDC6 Cdc6p 0.209
CWP2 Cwp2p 0.205
CDA2 Cda2p 0.204
RRT12 Rrt12p 0.203
CYR1 Cyr1p 0.201
MYO5 Myo5p 0.201
YSW1 Ysw1p 0.201
GIS1 Gis1p 0.191
CDC25 Cdc25p 0.189
SPO74 Spo74p 0.187
GID8 Gid8p 0.186
VID24 Vid24p 0.178
SPR28 Spr28p 0.177
CBK1 Cbk1p 0.175
VPS27 Vps27p 0.172
YHR140W hypothetical protein 0.171
YFR012W hypothetical protein 0.166
NPR2 Npr2p 0.155
SPO77 Spo77p 0.155
GAS2 Gas2p 0.154
GPI1 Gpi1p 0.152
MLC1 Mlc1p 0.150
PET494 Pet494p 0.148
PKH2 Pkh2p 0.147
IRC10 Irc10p 0.146
THI11 Thi11p 0.145
PPZ1 Ppz1p 0.142
SAP155 Sap155p 0.139
GAS4 Gas4p 0.139
CMK1 Cmk1p 0.139
TAO3 Tao3p 0.137
LOH1 Loh1p 0.137
EAF1 Eaf1p 0.137
LYS5 Lys5p 0.136
DFG16 Dfg16p 0.135
TPO2 Tpo2p 0.135
AFT1 Aft1p 0.134
HXT10 Hxt10p 0.133
YPK2 Ypk2p 0.132
RTT109 Rtt109p 0.130
SPS2 Sps2p 0.129
SWF1 Swf1p 0.129
SPO19 Spo19p 0.128
YGL230C hypothetical protein 0.128
YPL014W hypothetical protein 0.127
ATG7 Atg7p 0.127
BUD4 Bud4p 0.126
YKR075C hypothetical protein 0.126
NRG1 Nrg1p 0.125
ICL1 Icl1p 0.125
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.967
hlh-2 Protein HLH-2 0.963
egl-18 Protein EGL-18 0.948
egl-46 Protein EGL-46 0.904
vab-3 Protein VAB-3 0.891
dnc-2 Protein DNC-2 0.852
egl-15 Protein EGL-15 0.849
unc-53 Protein UNC-53 0.843
glp-1 Protein GLP-1 0.836
unc-6 Protein UNC-6 0.821
unc-52 Protein UNC-52 0.812
sax-3 Protein SAX-3 0.800
prp-8 Protein PRP-8 0.784
ceh-20 Protein CEH-20 0.778
unc-73 Protein UNC-73 0.777
lin-12 Protein LIN-12 0.759
hcp-3 Protein HCP-3 0.739
sma-6 Protein SMA-6 0.727
unc-62 Protein UNC-62 0.720
pry-1 Protein PRY-1 0.706
sli-1 Protein SLI-1 0.705
egl-8 Protein EGL-8 0.701
egg-6 Protein EGG-6 0.697
pan-1 Protein PAN-1 0.690
pkg-1 Protein PKG-1 0.684
elt-6 Protein ELT-6 0.681
snr-5 Protein SNR-5 0.680
C11E4.6 Protein C11E4.6 0.677
sur-6 Protein SUR-6 0.675
ect-2 Protein ECT-2 0.674
unc-104 Protein UNC-104 0.653
pha-4 Protein PHA-4 0.652
sem-5 Protein SEM-5 0.642
egl-13 Protein EGL-13 0.640
nap-1 Protein NAP-1 0.627
rpa-1 Protein RPA-1 0.626
par-5 Protein PAR-5 0.610
mel-28 Protein MEL-28 0.601
vbh-1 Protein VBH-1 0.601
mom-2 Protein MOM-2 0.593
skr-2 Protein SKR-2 0.593
let-60 Protein LET-60 0.591
mab-5 Protein MAB-5 0.590
hbl-1 Protein HBL-1 0.578
ife-1 Protein IFE-1 0.578
egl-30 Protein EGL-30 0.570
ajm-1 Protein AJM-1 0.570
lrp-2 Protein LRP-2 0.568
unc-9 Protein UNC-9 0.562
csn-1 Protein CSN-1 0.558
npp-1 Protein NPP-1 0.556
cam-1 Protein CAM-1 0.555
vha-8 Protein VHA-8 0.554
mes-3 Protein MES-3 0.554
scc-1 Protein SCC-1 0.553
cin-4 Protein CIN-4 0.549
CELE_F02E9.1 Protein F02E9.1 0.549
egg-1 Protein EGG-1 0.546
mbk-2 Protein MBK-2 0.543
sma-1 Protein SMA-1 0.543
pmk-1 Protein PMK-1 0.541
lin-11 Protein LIN-11 0.532
ran-1 Protein RAN-1 0.518
ncr-1 Protein NCR-1 0.516
cbd-1 Protein CBD-1 0.514
pdfr-1 Protein PDFR-1 0.512
mei-1 Protein MEI-1 0.510
cpg-2 Protein CPG-2 0.510
pat-12 Protein PAT-12 0.508
daf-11 Protein DAF-11 0.507
akt-2 Protein AKT-2 0.507
eps-8 Protein EPS-8 0.500
dao-5 Protein DAO-5 0.497
pes-7 Protein PES-7 0.496
epi-1 Protein EPI-1 0.496
nlg-1 Protein NLG-1 0.490
unc-60 Protein UNC-60 0.489
egl-5 Protein EGL-5 0.488
ppp-1 Protein PPP-1 0.488
CELE_C23G10.8 Protein C23G10.8 0.486
flt-1 Protein FLT-1 0.483
myo-3 Protein MYO-3 0.483
unc-32 Protein UNC-32 0.478
met-2 Protein MET-2 0.478
sec-24.2 Protein SEC-24.2 0.478
unc-42 Protein UNC-42 0.478
atn-1 Protein ATN-1 0.477
rfc-2 Protein RFC-2 0.476
daf-4 Protein DAF-4 0.476
smp-1 Protein SMP-1 0.475
ten-1 Protein TEN-1 0.475
hlh-1 Protein HLH-1 0.474
brp-1 Protein BRP-1 0.473
npp-4 Protein NPP-4 0.473
smu-2 Protein SMU-2 0.472
unc-43 Protein UNC-43 0.470
mex-5 Protein MEX-5 0.470
bar-1 Protein BAR-1 0.470
dsh-2 Protein DSH-2 0.466
vab-1 Protein VAB-1 0.460
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
EGFR epidermal growth factor receptor 1.000
GRB2 growth factor receptor-bound protein 2 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
ESR1 estrogen receptor 1 1.000
TP53 tumor protein p53 1.000
ATXN1 ataxin 1 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
FYN FYN oncogene related to SRC, FGR, YES 1.000
FLNA filamin A, alpha 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.999
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.999
QKI quaking homolog, KH domain RNA binding (mouse) 0.999
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.999
FN1 fibronectin 1 0.999
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.998
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.998
EP300 E1A binding protein p300 0.997
SMAD3 SMAD family member 3 0.997
RB1 retinoblastoma 1 0.996
CREBBP CREB binding protein 0.996
JUN jun proto-oncogene 0.995
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.995
NCOR1 nuclear receptor corepressor 1 0.994
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.994
ITSN1 intersectin 1 (SH3 domain protein) 0.993
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.992
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.991
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.991
MAPT microtubule-associated protein tau 0.991
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.991
HDAC1 histone deacetylase 1 0.991
ZYX zyxin 0.990
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.989
NCOR2 nuclear receptor corepressor 2 0.989
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.989
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.988
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.988
MAPK8 mitogen-activated protein kinase 8 0.986
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.986
SFN stratifin 0.986
ATN1 atrophin 1 0.985
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.985
LCK lymphocyte-specific protein tyrosine kinase 0.984
VIM vimentin 0.984
FHL2 four and a half LIM domains 2 0.983
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.983
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.983
SP1 Sp1 transcription factor 0.982
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.982
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.982
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.981
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.981
GAS7 growth arrest-specific 7 0.980
UBC ubiquitin C 0.978
CDK2 cyclin-dependent kinase 2 0.977
TJP1 tight junction protein 1 (zona occludens 1) 0.972
EED embryonic ectoderm development 0.971
BCAR1 breast cancer anti-estrogen resistance 1 0.969
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.966
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.964
FOS FBJ murine osteosarcoma viral oncogene homolog 0.961
SOS1 son of sevenless homolog 1 (Drosophila) 0.961
HDAC2 histone deacetylase 2 0.960
LRRK2 leucine-rich repeat kinase 2 0.957
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.956
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.956
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.955
ACTN1 actinin, alpha 1 0.955
PABPC1 poly(A) binding protein, cytoplasmic 1 0.952
RBPMS RNA binding protein with multiple splicing 0.951
FGFR1 fibroblast growth factor receptor 1 0.948
CAV1 caveolin 1, caveolae protein, 22kDa 0.948
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.947
NCK1 NCK adaptor protein 1 0.945
ACTB actin, beta 0.943
GSK3B glycogen synthase kinase 3 beta 0.943
IGF1R insulin-like growth factor 1 receptor 0.939
RPA1 replication protein A1, 70kDa 0.934
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.934
PCGF2 polycomb group ring finger 2 0.932
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.928
JAG1 jagged 1 0.924
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.924
SRSF3 serine/arginine-rich splicing factor 3 0.924
HDAC4 histone deacetylase 4 0.924
ILK integrin-linked kinase 0.921
MYH9 myosin, heavy chain 9, non-muscle 0.921
PKM2 pyruvate kinase, muscle 0.920
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.919
RAD21 RAD21 homolog (S. pombe) 0.917
ATF3 activating transcription factor 3 0.916
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.914
APP amyloid beta (A4) precursor protein 0.913
PLCG1 phospholipase C, gamma 1 0.913
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism