The network for 'establishment of protein localization to mitochondrion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment of protein localization to mitochondrion

The directed movement of a protein to a specific location in the mitochondrion.

Name Description Probability Func Analog Organism
TIM23 Tim23p 1.000
TOM22 Tom22p 1.000
TOM40 Tom40p 1.000
TIM44 Tim44p 1.000
MIA40 Mia40p 1.000
TOM70 Tom70p 1.000
TIM18 Tim18p 1.000
TIM17 Tim17p 1.000
TIM50 Tim50p 1.000
SSC1 Ssc1p 0.999
SAM35 Sam35p 0.999
TIM10 Tim10p 0.999
TOM20 Tom20p 0.999
TOM5 Tom5p 0.998
PAM18 Pam18p 0.997
TIM54 Tim54p 0.991
SAM50 Sam50p 0.988
TIM9 Tim9p 0.974
TIM22 Tim22p 0.974
TIM13 Tim13p 0.966
PAM16 Pam16p 0.965
TOM7 Tom7p 0.962
FCJ1 Fcj1p 0.926
MIM1 Mim1p 0.924
TIM8 Tim8p 0.921
MDM10 Mdm10p 0.846
MAS2 Mas2p 0.823
TIM21 Tim21p 0.790
ERV1 Erv1p 0.781
STI1 Sti1p 0.761
MGR2 Mgr2p 0.753
MGE1 Mge1p 0.577
TIM12 Tim12p 0.532
YLR099W-A hypothetical protein 0.456
ACP1 Acp1p 0.422
SIS1 Sis1p 0.404
SSE1 Sse1p 0.362
HSP60 Hsp60p 0.356
CAB4 Cab4p 0.347
ALT1 Alt1p 0.289
MDJ1 Mdj1p 0.273
DNM1 Dnm1p 0.252
HEM2 Hem2p 0.234
YHB1 Yhb1p 0.217
YTA12 Yta12p 0.212
MDM38 Mdm38p 0.209
IMP1 Imp1p 0.207
UGO1 Ugo1p 0.205
PET112 Pet112p 0.202
BFR1 Bfr1p 0.198
SAM37 Sam37p 0.194
TOM6 Tom6p 0.193
PAM17 Pam17p 0.193
ATP12 Atp12p 0.189
YME1 Yme1p 0.168
MGR3 Mgr3p 0.155
RDL2 Rdl2p 0.148
RIM13 Rim13p 0.139
ATG13 Atg13p 0.135
SGT2 Sgt2p 0.125
CUE4 Cue4p 0.124
COX2 Cox2p 0.122
IMP2 Imp2p 0.120
MAS1 Mas1p 0.117
COQ8 Coq8p 0.112
ALO1 Alo1p 0.112
YDJ1 Ydj1p 0.109
MDM32 Mdm32p 0.107
MOG1 Mog1p 0.102
KAR2 Kar2p 0.102
ATP11 Atp11p 0.099
YFH1 Yfh1p 0.098
YER064C hypothetical protein 0.096
AIM43 Aim43p 0.094
TPD3 Tpd3p 0.091
SSA2 Ssa2p 0.090
GRX5 Grx5p 0.090
PPA2 Ppa2p 0.089
YLR253W hypothetical protein 0.086
YAH1 Yah1p 0.082
YBL039W-B hypothetical protein 0.080
CPR3 Cpr3p 0.076
OXA1 Oxa1p 0.074
RNR3 Rnr3p 0.074
UPS1 Ups1p 0.073
RIM2 Rim2p 0.073
NTA1 Nta1p 0.072
SSA3 Ssa3p 0.069
SPS100 Sps100p 0.068
COX20 Cox20p 0.068
ALD6 Ald6p 0.066
MTM1 Mtm1p 0.065
ECM15 Ecm15p 0.065
VMA13 Vma13p 0.063
GAL7 Gal7p 0.063
YLH47 Ylh47p 0.063
YLR031W hypothetical protein 0.062
CLU1 Clu1p 0.062
MDV1 Mdv1p 0.060
FMP25 Fmp25p 0.059
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
fkb-6 Protein FKB-6 0.547
C34C12.8 Protein C34C12.8 0.213
C30C11.4 Protein C30C11.4 0.119
cct-1 Protein CCT-1 0.119
eif-3.K Protein EIF-3.K 0.097
dnj-13 Protein DNJ-13 0.092
cct-6 Protein CCT-6 0.089
daf-21 Protein DAF-21 0.080
cct-2 Protein CCT-2 0.070
CELE_F45H11.5 Protein F45H11.5 0.070
cct-4 Protein CCT-4 0.069
mrps-14 Protein MRPS-14 0.063
dnj-12 Protein DNJ-12 0.057
mrpl-12 Protein MRPL-12 0.052
cyn-7 Protein CYN-7 0.051
tomm-7 Protein TOMM-7 0.047
tag-294 Protein TAG-294 0.041
cct-5 Protein CCT-5 0.036
ttll-12 Protein TTLL-12 0.036
tin-9.1 Protein TIN-9.1 0.035
CELE_K08F4.2 Protein K08F4.2 0.034
hrp-1 Protein HRP-1 0.033
ddp-1 Protein DDP-1 0.033
CELE_C01G10.8 Protein C01G10.8 0.029
scpl-4 Protein SCPL-4 0.029
cyn-1 Protein CYN-1 0.027
cra-1 Protein CRA-1 0.026
Y39A3CL.3 Protein Y39A3CL.3 0.026
adr-1 Protein ADR-1 0.026
tars-1 Protein TARS-1 0.026
hsp-4 Protein HSP-4 0.025
F31D4.2 Protein F31D4.2 0.025
let-711 Protein LET-711 0.022
mag-1 Protein MAG-1 0.022
hsp-6 Protein HSP-6 0.022
F56D1.2 Protein F56D1.2 0.021
CELE_Y106G6H.5 Protein Y106G6H.5 0.020
hap-1 Protein HAP-1 0.020
snr-5 Protein SNR-5 0.020
uba-1 Protein UBA-1 0.019
qars-1 Protein QARS-1 0.019
hsp-1 Protein HSP-1 0.018
eftu-2 Protein EFTU-2 0.018
CELE_Y105E8A.11 Protein Y105E8A.11 0.018
clk-1 Protein CLK-1 0.017
CELE_Y53F4B.14 Protein Y53F4B.14 0.016
T18D3.1 Protein T18D3.1 0.016
F13G3.10 Protein F13G3.10 0.016
rmo-1 Protein RMO-1 0.016
tba-1 Protein TBA-1 0.016
F31D4.9 Protein F31D4.9 0.016
tag-210 Protein TAG-210 0.016
rsp-3 Protein RSP-3 0.015
hpo-18 Protein HPO-18 0.015
prp-8 Protein PRP-8 0.015
icd-1 Protein ICD-1 0.015
T06D8.5 Protein T06D8.5 0.015
nap-1 Protein NAP-1 0.015
mrps-21 Protein MRPS-21 0.014
CELE_C10C6.6 Protein C10C6.6 0.014
F33H2.3 Protein F33H2.3 0.014
C36E8.1 Protein C36E8.1 0.013
Y22D7AL.10 Protein Y22D7AL.10 0.013
tin-13 Protein TIN-13 0.013
dnj-21 Protein DNJ-21 0.013
ahcy-1 Protein AHCY-1 0.012
C30H6.7 Protein C30H6.7 0.012
T20B12.7 Protein T20B12.7 0.012
daf-1 Protein DAF-1 0.012
dnj-19 Protein DNJ-19 0.011
cls-2 Protein CLS-2 0.011
CELE_Y69A2AR.3 Protein Y69A2AR.3 0.011
sti-1 Protein STI-1 0.011
unc-24 Protein UNC-24 0.011
cdc-48.2 Protein CDC-48.2 0.011
T09B4.9 Protein T09B4.9 0.011
H17B01.4 Protein H17B01.4 0.011
ima-3 Protein IMA-3 0.011
ccf-1 Protein CCF-1 0.010
CELE_Y116A8C.30 Protein Y116A8C.30 0.010
cal-4 Protein CAL-4 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.998
HSPA1B heat shock 70kDa protein 1B 0.998
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.963
BCL2 B-cell CLL/lymphoma 2 0.932
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.924
MARCH5 membrane-associated ring finger (C3HC4) 5 0.913
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.882
BAX BCL2-associated X protein 0.866
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.839
PPID peptidylprolyl isomerase D 0.782
BCL2L1 BCL2-like 1 0.770
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.709
HSPA1A heat shock 70kDa protein 1A 0.576
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.571
BECN1 beclin 1, autophagy related 0.515
HSPA8 heat shock 70kDa protein 8 0.497
NUB1 negative regulator of ubiquitin-like proteins 1 0.450
MAP2K4 mitogen-activated protein kinase kinase 4 0.448
BAD BCL2-associated agonist of cell death 0.446
MAPK8 mitogen-activated protein kinase 8 0.411
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.356
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 0.277
MRPL24 mitochondrial ribosomal protein L24 0.258
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.240
TP53BP2 tumor protein p53 binding protein, 2 0.223
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.219
PINK1 PTEN induced putative kinase 1 0.218
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.215
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.214
STIP1 stress-induced-phosphoprotein 1 0.193
BAK1 BCL2-antagonist/killer 1 0.176
DNM1L dynamin 1-like 0.161
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.156
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.148
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.144
MEOX2 mesenchyme homeobox 2 0.140
HUWE1 HECT, UBA and WWE domain containing 1 0.126
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.125
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.123
TCP1 t-complex 1 0.114
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.106
HSPH1 heat shock 105kDa/110kDa protein 1 0.105
GADD45A growth arrest and DNA-damage-inducible, alpha 0.104
BAG3 BCL2-associated athanogene 3 0.104
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 0.098
RNF144B ring finger protein 144B 0.097
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.096
PPP5C protein phosphatase 5, catalytic subunit 0.095
SKA3 spindle and kinetochore associated complex subunit 3 0.093
BIK BCL2-interacting killer (apoptosis-inducing) 0.093
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.087
SMCR7L Smith-Magenis syndrome chromosome region, candidate 7-like 0.086
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.085
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.080
MAGEH1 melanoma antigen family H, 1 0.077
KIAA0664 KIAA0664 0.077
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.077
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.076
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.075
COQ3 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) 0.069
EIF5 eukaryotic translation initiation factor 5 0.068
CDK7 cyclin-dependent kinase 7 0.067
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.065
MRPS12 mitochondrial ribosomal protein S12 0.063
TMED2 transmembrane emp24 domain trafficking protein 2 0.062
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 0.059
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.056
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.053
UBE2N ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) 0.053
ETF1 eukaryotic translation termination factor 1 0.052
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 0.051
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.048
UBE2G1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.046
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.046
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.045
NMD3 NMD3 homolog (S. cerevisiae) 0.045
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.045
MRPL35 mitochondrial ribosomal protein L35 0.044
NUDC nuclear distribution gene C homolog (A. nidulans) 0.043
SS18 synovial sarcoma translocation, chromosome 18 0.043
AMBRA1 autophagy/beclin-1 regulator 1 0.043
XPO7 exportin 7 0.042
BZW1 basic leucine zipper and W2 domains 1 0.040
TMX2 thioredoxin-related transmembrane protein 2 0.040
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.040
SERTAD4 SERTA domain containing 4 0.038
GHITM growth hormone inducible transmembrane protein 0.036
CANX calnexin 0.035
BCAP31 B-cell receptor-associated protein 31 0.035
SLC25A46 solute carrier family 25, member 46 0.035
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.034
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.034
PEX19 peroxisomal biogenesis factor 19 0.033
KIF5B kinesin family member 5B 0.033
YAF2 YY1 associated factor 2 0.033
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast) 0.033
TBK1 TANK-binding kinase 1 0.031
CCNG1 cyclin G1 0.030
DCTN6 dynactin 6 0.030
EPRS glutamyl-prolyl-tRNA synthetase 0.030
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Mus musculus
Name Description Probability Func Analog Organism
Hspd1 heat shock protein 1 (chaperonin) 0.964
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.912
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.746
Rpgrip1l Rpgrip1-like 0.678
Mcl1 myeloid cell leukemia sequence 1 0.494
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.424
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.356
Hspa8 heat shock protein 8 0.347
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.341
Bax BCL2-associated X protein 0.329
Iqcb1 IQ calmodulin-binding motif containing 1 0.323
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.301
Nphp1 nephronophthisis 1 (juvenile) homolog (human) 0.252
Hsph1 heat shock 105kDa/110kDa protein 1 0.194
Grpel1 GrpE-like 1, mitochondrial 0.100
Canx calnexin 0.096
Pdcd6ip programmed cell death 6 interacting protein 0.083
Ahi1 Abelson helper integration site 1 0.079
Lrpprc leucine-rich PPR-motif containing 0.060
Hspa9 heat shock protein 9 0.057
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.056
Ndufaf4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 0.053
Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.052
Timm8a1 translocase of inner mitochondrial membrane 8 homolog a1 (yeast) 0.042
Bak1 BCL2-antagonist/killer 1 0.041
Tomm70a translocase of outer mitochondrial membrane 70 homolog A (yeast) 0.037
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.037
Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 0.035
Arpc4 actin related protein 2/3 complex, subunit 4 0.035
Mta1 metastasis associated 1 0.034
Immt inner membrane protein, mitochondrial 0.031
Mks1 Meckel syndrome, type 1 0.027
Nmd3 NMD3 homolog (S. cerevisiae) 0.027
Timm10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.026
Trp53 transformation related protein 53 0.026
Pus1 pseudouridine synthase 1 0.023
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.021
Napb N-ethylmaleimide sensitive fusion protein attachment protein beta 0.021
Mfn2 mitofusin 2 0.020
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.019
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.019
1110002N22Rik RIKEN cDNA 1110002N22 gene 0.019
Eprs glutamyl-prolyl-tRNA synthetase 0.018
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.017
Bcl2 B-cell leukemia/lymphoma 2 0.017
Mrpl46 mitochondrial ribosomal protein L46 0.016
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.016
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.016
Afg3l2 AFG3(ATPase family gene 3)-like 2 (yeast) 0.016
Men1 multiple endocrine neoplasia 1 0.015
Rab4b RAB4B, member RAS oncogene family 0.015
Hspb1 heat shock protein 1 0.013
Tuba4a tubulin, alpha 4A 0.012
Dld dihydrolipoamide dehydrogenase 0.012
Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.012
Tubb6 tubulin, beta 6 0.011
Mrpl10 mitochondrial ribosomal protein L10 0.011
Mrps18a mitochondrial ribosomal protein S18A 0.011
Bag2 BCL2-associated athanogene 2 0.011
Dnm1l dynamin 1-like 0.010
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.010
Ube2f ubiquitin-conjugating enzyme E2F (putative) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hspd1 heat shock protein 1 (chaperonin) 0.031
Hsph1 heat shock 105/110 protein 1 0.024
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.018
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.018
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.011