The network for 'purine ribonucleoside triphosphate metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine ribonucleoside triphosphate metabolic process

The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATP1 Atp1p 0.968
ATP4 Atp4p 0.926
PET9 Pet9p 0.894
CYT1 Cyt1p 0.807
QCR8 Qcr8p 0.794
ATP14 Atp14p 0.788
RHO1 Rho1p 0.786
COX4 Cox4p 0.782
QCR2 Qcr2p 0.750
YPT52 Ypt52p 0.708
COR1 Cor1p 0.703
NDE1 Nde1p 0.702
ATP18 Atp18p 0.674
BEM3 Bem3p 0.667
SSL1 Ssl1p 0.627
COX6 Cox6p 0.598
AVO1 Avo1p 0.595
COX9 Cox9p 0.589
SDH2 Sdh2p 0.579
STE4 Ste4p 0.569
TFB4 Tfb4p 0.563
INH1 Inh1p 0.554
STI1 Sti1p 0.553
ATP7 Atp7p 0.552
COX13 Cox13p 0.500
COX1 Cox1p 0.485
ATP6 Atp6p 0.452
YPT1 Ypt1p 0.452
ATP15 Atp15p 0.449
QCR6 Qcr6p 0.446
ACB1 Acb1p 0.439
SPA2 Spa2p 0.431
GYL1 Gyl1p 0.425
FKH1 Fkh1p 0.413
ATP5 Atp5p 0.405
COX12 Cox12p 0.405
RIP1 Rip1p 0.395
CKA2 Cka2p 0.386
TRS65 Trs65p 0.385
ISW1 Isw1p 0.384
TIM11 Tim11p 0.376
COX2 Cox2p 0.373
STE11 Ste11p 0.373
BEM4 Bem4p 0.371
TSR1 Tsr1p 0.366
SUI3 Sui3p 0.361
PRP8 Prp8p 0.356
YIP3 Yip3p 0.353
YPT31 Ypt31p 0.348
MDS3 Mds3p 0.337
ATP20 Atp20p 0.336
COX8 Cox8p 0.333
KIN28 Kin28p 0.331
YDJ1 Ydj1p 0.331
QCR7 Qcr7p 0.325
ATP17 Atp17p 0.320
RPN1 Rpn1p 0.317
CCL1 Ccl1p 0.314
YOL087C hypothetical protein 0.314
NYV1 Nyv1p 0.309
SWI1 Swi1p 0.308
QCR9 Qcr9p 0.306
SSA4 Ssa4p 0.303
ATP16 Atp16p 0.291
YCS4 Ycs4p 0.281
YPT6 Ypt6p 0.278
YPT53 Ypt53p 0.276
SEC16 Sec16p 0.271
NOG2 Nog2p 0.262
SEC13 Sec13p 0.260
GCD6 Gcd6p 0.259
MYO5 Myo5p 0.256
ITC1 Itc1p 0.254
COX5A Cox5ap 0.254
SSE1 Sse1p 0.251
PXA1 Pxa1p 0.251
ATP2 Atp2p 0.249
SLT2 Slt2p 0.248
STE2 Ste2p 0.245
COB Cobp 0.236
CLU1 Clu1p 0.236
VPS15 Vps15p 0.225
VPS21 Vps21p 0.221
YPT10 Ypt10p 0.221
TFB3 Tfb3p 0.219
GDI1 Gdi1p 0.219
KOG1 Kog1p 0.217
UBR1 Ubr1p 0.217
TOM1 Tom1p 0.216
QCR10 Qcr10p 0.216
TFB5 Tfb5p 0.214
MIR1 Mir1p 0.210
MKK1 Mkk1p 0.208
CKA1 Cka1p 0.201
SSK2 Ssk2p 0.197
SSA1 Ssa1p 0.193
VPS4 Vps4p 0.192
TSC11 Tsc11p 0.188
COX3 Cox3p 0.188
CDC25 Cdc25p 0.187
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
D1081.8 Protein D1081.8 0.702
F58F12.1 Protein F58F12.1 0.650
goa-1 Protein GOA-1 0.581
crt-1 Protein CRT-1 0.466
CELE_F29C4.2 Protein F29C4.2 0.445
gei-18 Protein GEI-18 0.408
abts-1 Protein ABTS-1 0.398
mpk-1 Protein MPK-1 0.386
dpf-3 Protein DPF-3 0.383
chc-1 Protein CHC-1 0.380
F45H10.3 Protein F45H10.3 0.379
unc-54 Protein UNC-54 0.337
ret-1 Protein RET-1 0.335
csr-1 Protein CSR-1 0.332
F36A2.7 Protein F36A2.7 0.322
pkg-1 Protein PKG-1 0.317
F45H10.2 Protein F45H10.2 0.278
unc-45 Protein UNC-45 0.277
aspm-1 Protein ASPM-1 0.275
ant-1.1 Protein ANT-1.1 0.272
sem-5 Protein SEM-5 0.267
gei-4 Protein GEI-4 0.262
atp-5 Protein ATP-5 0.226
R53.4 Protein R53.4 0.222
tat-1 Protein TAT-1 0.221
cyc-1 Protein CYC-1 0.218
coq-8 Protein COQ-8 0.210
etr-1 Protein ETR-1 0.207
rpa-2 Protein RPA-2 0.205
atp-2 Protein ATP-2 0.201
ncs-2 Protein NCS-2 0.200
dad-1 Protein DAD-1 0.199
R04F11.2 Protein R04F11.2 0.191
hsp-16.1 Protein HSP-16.1 0.191
daf-4 Protein DAF-4 0.184
cyk-4 Protein CYK-4 0.183
eef-1A.1 Protein EEF-1A.1 0.180
lin-45 Protein LIN-45 0.178
F54D12.4 Protein F54D12.4 0.176
atfs-1 Protein ATFS-1 0.171
rfc-3 Protein RFC-3 0.167
ced-10 Protein CED-10 0.166
rme-4 Protein RME-4 0.163
akt-1 Protein AKT-1 0.160
pme-1 Protein PME-1 0.160
ptp-1 Protein PTP-1 0.160
mcm-7 Protein MCM-7 0.155
got-2.1 Protein GOT-2.1 0.152
miro-1 Protein MIRO-1 0.151
unc-15 Protein UNC-15 0.149
smp-1 Protein SMP-1 0.147
mai-2 Protein MAI-2 0.146
C53C9.2 Protein C53C9.2 0.143
CELE_F08D12.1 Protein F08D12.1 0.143
CELE_F14E5.2 Protein F14E5.2 0.139
T22C1.6 Protein T22C1.6 0.139
idhb-1 Protein IDHB-1 0.138
nhr-10 Protein NHR-10 0.137
ykt-6 Protein YKT-6 0.137
ucr-1 Protein UCR-1 0.135
dnj-16 Protein DNJ-16 0.135
eat-20 Protein EAT-20 0.134
cdc-42 Protein CDC-42 0.132
ZK484.1 Protein ZK484.1 0.131
F23H11.5 Protein F23H11.5 0.130
tomm-20 Protein TOMM-20 0.130
B0495.2 Protein B0495.2 0.130
imb-1 Protein IMB-1 0.124
nra-1 Protein NRA-1 0.123
itr-1 Protein ITR-1 0.122
CELE_C24D10.5 Protein C24D10.5 0.122
gdh-1 Protein GDH-1 0.121
CELE_W07A8.2 Protein W07A8.2 0.121
zyg-9 Protein ZYG-9 0.120
gpb-1 Protein GPB-1 0.120
pgam-5 Protein PGAM-5 0.119
T23F11.1 Protein T23F11.1 0.119
immt-2 Protein IMMT-2 0.118
inft-2 Protein INFT-2 0.118
vpr-1 Protein VPR-1 0.117
rga-3 Protein RGA-3 0.114
spd-2 Protein SPD-2 0.113
cyc-2.1 Protein CYC-2.1 0.113
let-60 Protein LET-60 0.113
gpr-2 Protein GPR-2 0.112
sas-4 Protein SAS-4 0.108
CELE_Y47G6A.18 Protein Y47G6A.18 0.107
hmr-1 Protein HMR-1 0.107
rfc-1 Protein RFC-1 0.106
scc-3 Protein SCC-3 0.106
tba-2 Protein TBA-2 0.103
mel-28 Protein MEL-28 0.102
pptr-2 Protein PPTR-2 0.101
nduf-7 Protein NDUF-7 0.100
F29B9.8 Protein F29B9.8 0.098
pat-12 Protein PAT-12 0.098
H11E01.3 Protein H11E01.3 0.098
lin-5 Protein LIN-5 0.098
tag-341 Protein TAG-341 0.097
usp-14 Protein USP-14 0.097
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
tomm34 translocase of outer mitochondrial membrane 34 0.047
ndufs2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 0.041
tnni2a.4 troponin I, skeletal, fast 2a.4 0.040
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.038
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.034
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.031
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.030
uqcrc2a ubiquinol-cytochrome c reductase core protein IIa 0.029
pabpc1a poly A binding protein, cytoplasmic 1 a 0.028
uqcrc2b ubiquinol-cytochrome c reductase core protein IIb 0.027
sox2 SRY-box containing gene 2 0.026
ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.026
tpm3 tropomyosin 3 0.026
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.024
tnnt3b troponin T3b, skeletal, fast 0.024
hspd1 heat shock 60kD protein 1 (chaperonin) 0.024
ckma creatine kinase, muscle a 0.023
uqcrc1 ubiquinol-cytochrome c reductase core protein I 0.023
tpm4 tropomyosin 4 0.022
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.022
zgc:56085 zgc:56085 0.022
tnnc1b troponin C type 1b (slow) 0.021
idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.021
rab1a RAB1A, member RAS oncogene family 0.021
atp5c1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.020
atp5f1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1 0.020
pvrl1b poliovirus receptor-related 1b 0.020
aldocb aldolase C, fructose-bisphosphate, b 0.020
sncb synuclein, beta 0.019
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.019
aaas achalasia, adrenocortical insufficiency, alacrimia 0.019
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.019
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.018
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.018
pgam2 phosphoglycerate mutase 2 (muscle) 0.017
baxa bcl2-associated X protein, a 0.017
zgc:111961 zgc:111961 0.017
hk1 hexokinase 1 0.017
hsp90a.2 heat shock protein 90-alpha 2 0.017
bida BH3 interacting domain death agonist 0.017
dusp6 dual specificity phosphatase 6 0.017
ndufb8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 0.017
ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase) 0.017
zgc:66286 zgc:66286 0.017
mat2a methionine adenosyltransferase II, alpha 0.016
pak2a p21 (CDKN1A)-activated kinase 2a 0.016
sncgb synuclein, gamma b (breast cancer-specific protein 1) 0.015
copeb core promoter element binding protein 0.015
esyt3 extended synaptotagmin-like protein 3 0.015
dclk2 doublecortin-like kinase 2 0.015
rab25 RAB25, member RAS oncogene family 0.015
ndufa9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 0.015
si:ch211-232m7.1 si:ch211-232m7.1 0.014
tm9sf2 transmembrane 9 superfamily member 2 0.014
ndufa10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 0.014
aldh2b aldehyde dehydrogenase 2b 0.014
mcl1b myeloid cell leukemia sequence 1b 0.014
sept2 septin 2 0.014
arpc5a actin related protein 2/3 complex, subunit 5A 0.013
rab7 RAB7, member RAS oncogene family 0.013
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.013
pvalb4 parvalbumin 4 0.013
atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.013
pvalb3 parvalbumin 3 0.012
atp2a1l ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like 0.012
cnn2 calponin 2 0.012
atp5ib ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e, duplicate b 0.012
zbtb4 zinc finger and BTB domain containing 4 0.012
zgc:73329 zgc:73329 0.012
hspg2 heparan sulfate proteoglycan 2 0.012
pfn2 profilin 2 0.011
sox19a SRY-box containing gene 19a 0.011
polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.011
im:7137453 im:7137453 0.011
bmp7a bone morphogenetic protein 7a 0.011
ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.011
nrarpb notch-regulated ankyrin repeat protein b 0.011
pvalb1 parvalbumin 1 0.011
hspa4a heat shock protein 4a 0.011
ndufb9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 0.011
fgf6a fibroblast growth factor 6a 0.011
mecp2 methyl CpG binding protein 2 0.010
rab13 RAB13, member RAS oncogene family 0.010
scinlb scinderin like b 0.010
skp1 S-phase kinase-associated protein 1 0.010
ppme1 protein phosphatase methylesterase 1 0.010
acta1b actin, alpha 1b, skeletal muscle 0.010
cx30.3 connexin 30.3 0.010
ctsc cathepsin C 0.010
gsna gelsolin a 0.010
atp5l ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.990
Pten CG5671 gene product from transcript CG5671-RB 0.951
chic chickadee 0.927
Khc Kinesin heavy chain 0.845
Rheb CG1081 gene product from transcript CG1081-RA 0.811
trio CG18214 gene product from transcript CG18214-RA 0.713
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.608
baz bazooka 0.576
WASp CG1520 gene product from transcript CG1520-RA 0.568
Eph Eph receptor tyrosine kinase 0.557
dm diminutive 0.551
Myo31DF Myosin 31DF 0.547
arm armadillo 0.524
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.501
Moe Moesin 0.471
ATPsyn-gamma ATP synthase-gamma chain 0.435
shi shibire 0.424
CG10664 CG10664 gene product from transcript CG10664-RB 0.421
CG8155 CG8155 gene product from transcript CG8155-RA 0.417
stai stathmin 0.407
rhea CG6831 gene product from transcript CG6831-RA 0.395
CG11376 CG11376 gene product from transcript CG11376-RA 0.385
trbl tribbles 0.381
porin CG6647 gene product from transcript CG6647-RA 0.381
Gie novel GTPase indispensable for equal segregation of chromosomes 0.366
Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 0.363
Ced-12 CG5336 gene product from transcript CG5336-RA 0.357
N Notch 0.353
tsr twinstar 0.353
Mad Mothers against dpp 0.349
CG3321 CG3321 gene product from transcript CG3321-RC 0.343
rok Rho-kinase 0.333
E(z) Enhancer of zeste 0.327
pod1 CG4532 gene product from transcript CG4532-RF 0.326
ben bendless 0.325
CG12079 CG12079 gene product from transcript CG12079-RA 0.316
kibra kibra ortholog 0.314
mbt mushroom bodies tiny 0.309
Uba1 Ubiquitin activating enzyme 1 0.305
CG3731 CG3731 gene product from transcript CG3731-RA 0.305
SNF1A SNF1A/AMP-activated protein kinase 0.294
ND75 NADH:ubiquinone reductase 75kD subunit precursor 0.288
Caps Calcium activated protein for secretion 0.284
raps rapsynoid 0.282
trp transient receptor potential 0.281
ken ken and barbie 0.278
flw flapwing 0.275
Git CG16728 gene product from transcript CG16728-RA 0.273
Srp68 CG5064 gene product from transcript CG5064-RA 0.272
loco locomotion defects 0.268
cenG1A centaurin gamma 1A 0.267
Wnk CG7177 gene product from transcript CG7177-RA 0.262
ATPsyn-b ATP synthase, subunit b 0.255
Arf79F ADP ribosylation factor 79F 0.247
Tsc1 CG6147 gene product from transcript CG6147-RA 0.244
NaCP60E Na channel protein 60E 0.242
Pak PAK-kinase 0.242
Rab6 Rab-protein 6 0.241
rictor rapamycin-insensitive companion of Tor 0.230
ik2 IkappaB kinase-like 2 0.230
Oscp Oligomycin sensitivity-conferring protein 0.230
mys myospheroid 0.227
CG4169 CG4169 gene product from transcript CG4169-RA 0.224
Pkn Protein kinase related to protein kinase N 0.223
Dhc64C Dynein heavy chain 64C 0.223
CG32772 CG32772 gene product from transcript CG32772-RC 0.222
Stat92E Signal-transducer and activator of transcription protein at 92E 0.219
sqh spaghetti squash 0.217
Syx7 Syntaxin 7 0.217
CG3680 CG3680 gene product from transcript CG3680-RA 0.216
Smox Smad on X 0.213
Tcp-1eta CG8351 gene product from transcript CG8351-RA 0.209
Gga CG3002 gene product from transcript CG3002-RB 0.209
dys dysfusion 0.206
pbl pebble 0.205
shrb shrub 0.205
S6k RPS6-p70-protein kinase 0.204
cdm cadmus 0.204
Sos Son of sevenless 0.203
nwk nervous wreck 0.200
sesB stress-sensitive B 0.196
SdhB Succinate dehydrogenase B 0.195
pyd polychaetoid 0.193
mop myopic 0.188
blw bellwether 0.187
dos daughter of sevenless 0.183
cher cheerio 0.183
wupA wings up A 0.182
eff effete 0.182
Rab7 Rab-protein 7 0.182
lsn larsen 0.177
kst karst 0.177
Vha13 Vacuolar H[+] ATPase G-subunit 0.176
mbc myoblast city 0.175
Vps16A Vacuolar protein sorting 16A 0.171
Lrrk Leucine-rich repeat kinase 0.171
Ephrin CG1862 gene product from transcript CG1862-RA 0.170
Pk61C Protein kinase 61C 0.170
Act87E Actin 87E 0.167
nos nanos 0.166
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
DNM2 dynamin 2 0.998
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.993
PTK2 PTK2 protein tyrosine kinase 2 0.989
EGFR epidermal growth factor receptor 0.986
RAB1A RAB1A, member RAS oncogene family 0.984
FGFR2 fibroblast growth factor receptor 2 0.978
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.974
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.973
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.966
RAB5A RAB5A, member RAS oncogene family 0.956
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.953
SNX9 sorting nexin 9 0.953
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.946
RHOA ras homolog gene family, member A 0.943
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.942
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.941
SFN stratifin 0.940
CDK7 cyclin-dependent kinase 7 0.937
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.929
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.926
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.924
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.915
S100A8 S100 calcium binding protein A8 0.915
TOR1A torsin family 1, member A (torsin A) 0.906
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.905
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.899
SH3KBP1 SH3-domain kinase binding protein 1 0.893
ITSN1 intersectin 1 (SH3 domain protein) 0.891
RANBP9 RAN binding protein 9 0.888
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.888
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.885
TNNC1 troponin C type 1 (slow) 0.884
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.881
STAT5A signal transducer and activator of transcription 5A 0.874
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.868
DNM1 dynamin 1 0.867
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.863
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.860
GRB7 growth factor receptor-bound protein 7 0.860
ILF2 interleukin enhancer binding factor 2, 45kDa 0.858
TPM1 tropomyosin 1 (alpha) 0.848
RIN3 Ras and Rab interactor 3 0.846
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.841
FGFR1 fibroblast growth factor receptor 1 0.839
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.833
SH3RF1 SH3 domain containing ring finger 1 0.831
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.827
ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 0.827
CCNH cyclin H 0.826
HIPK2 homeodomain interacting protein kinase 2 0.817
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.816
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.808
EEA1 early endosome antigen 1 0.802
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.797
ARRB1 arrestin, beta 1 0.795
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.793
MPDZ multiple PDZ domain protein 0.782
SEPT2 septin 2 0.781
GRB2 growth factor receptor-bound protein 2 0.777
NCKAP1 NCK-associated protein 1 0.772
EPS15 epidermal growth factor receptor pathway substrate 15 0.771
THOC4 THO complex 4 0.766
PLCG1 phospholipase C, gamma 1 0.764
ABI1 abl-interactor 1 0.756
ACTB actin, beta 0.750
FOS FBJ murine osteosarcoma viral oncogene homolog 0.748
BAG1 BCL2-associated athanogene 0.746
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.746
RBBP4 retinoblastoma binding protein 4 0.744
TSC2 tuberous sclerosis 2 0.739
IMMT inner membrane protein, mitochondrial 0.737
SYNJ1 synaptojanin 1 0.736
TRIM63 tripartite motif containing 63 0.732
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.730
HSPB1 heat shock 27kDa protein 1 0.728
RHOC ras homolog gene family, member C 0.727
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.724
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.724
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.723
ARRB2 arrestin, beta 2 0.719
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.719
RPTOR regulatory associated protein of MTOR, complex 1 0.715
NCK1 NCK adaptor protein 1 0.713
TK1 thymidine kinase 1, soluble 0.711
NCAPD2 non-SMC condensin I complex, subunit D2 0.707
S100B S100 calcium binding protein B 0.706
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.704
DLD dihydrolipoamide dehydrogenase 0.702
TRAF1 TNF receptor-associated factor 1 0.696
PARP1 poly (ADP-ribose) polymerase 1 0.689
HSPA1B heat shock 70kDa protein 1B 0.687
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.683
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.674
PFN1 profilin 1 0.666
SH3BP2 SH3-domain binding protein 2 0.665
HMOX2 heme oxygenase (decycling) 2 0.657
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Lrrk2 leucine-rich repeat kinase 2 0.994
Efnb2 ephrin B2 0.985
Epha4 Eph receptor A4 0.984
Bcl2 B-cell leukemia/lymphoma 2 0.982
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.963
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.962
Braf Braf transforming gene 0.954
Grb2 growth factor receptor bound protein 2 0.931
Rac1 RAS-related C3 botulinum substrate 1 0.912
Dnm1 dynamin 1 0.898
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.891
Cyc1 cytochrome c-1 0.863
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.862
Rpgrip1l Rpgrip1-like 0.853
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.852
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.821
Kl klotho 0.801
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.779
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.763
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.750
Lepr leptin receptor 0.719
Plxna1 plexin A1 0.692
Vdr vitamin D receptor 0.686
Lama5 laminin, alpha 5 0.686
Ntf3 neurotrophin 3 0.684
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.675
Ephb2 Eph receptor B2 0.673
Plec plectin 0.672
Mtap2 microtubule-associated protein 2 0.666
Myo1c myosin IC 0.652
Arrb2 arrestin, beta 2 0.646
Ilk integrin linked kinase 0.627
Cox7a2 cytochrome c oxidase, subunit VIIa 2 0.622
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.594
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.588
Tnnt3 troponin T3, skeletal, fast 0.584
Flii flightless I homolog (Drosophila) 0.582
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.581
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 0.577
Dock1 dedicator of cytokinesis 1 0.570
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.569
Tnni2 troponin I, skeletal, fast 2 0.559
Rasa3 RAS p21 protein activator 3 0.552
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.551
Spna2 spectrin alpha 2 0.545
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.543
Irf1 interferon regulatory factor 1 0.543
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 0.539
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.532
Cd151 CD151 antigen 0.529
Rasgrp1 RAS guanyl releasing protein 1 0.528
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.527
Syn2 synapsin II 0.526
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.525
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.524
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.513
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.510
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.510
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.507
Spnb2 spectrin beta 2 0.504
Cd44 CD44 antigen 0.502
Ctnnb1 catenin (cadherin associated protein), beta 1 0.502
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.494
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.489
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.488
Ccl2 chemokine (C-C motif) ligand 2 0.484
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.482
Ccr2 chemokine (C-C motif) receptor 2 0.480
Nphs2 nephrosis 2 homolog, podocin (human) 0.467
Nf1 neurofibromatosis 1 0.456
Pten phosphatase and tensin homolog 0.436
Arhgap30 Rho GTPase activating protein 30 0.436
Fh1 fumarate hydratase 1 0.428
Arrb1 arrestin, beta 1 0.426
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.425
Pdgfb platelet derived growth factor, B polypeptide 0.416
Lmna lamin A 0.415
Capn2 calpain 2 0.410
Rbbp7 retinoblastoma binding protein 7 0.408
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.407
Ndufa9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 0.406
Rplp0 ribosomal protein, large, P0 0.405
Cnr1 cannabinoid receptor 1 (brain) 0.405
Klf6 Kruppel-like factor 6 0.400
Plxnb1 plexin B1 0.400
Snx6 sorting nexin 6 0.398
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.396
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.396
Smc1a structural maintenance of chromosomes 1A 0.396
Vhl von Hippel-Lindau tumor suppressor 0.393
Cbl Casitas B-lineage lymphoma 0.392
Ncf1 neutrophil cytosolic factor 1 0.389
Src Rous sarcoma oncogene 0.388
Grid1 glutamate receptor, ionotropic, delta 1 0.387
Adam11 a disintegrin and metallopeptidase domain 11 0.386
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.386
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.384
Eps15 epidermal growth factor receptor pathway substrate 15 0.381
Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 0.379
Gsk3b glycogen synthase kinase 3 beta 0.378
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.848
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.794
Gria2 glutamate receptor, ionotropic, AMPA 2 0.705
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.652
Arl1 ADP-ribosylation factor-like 1 0.650
Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d 0.578
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.531
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.515
Anxa1 annexin A1 0.477
Itgb1 integrin, beta 1 0.477
Cox7b cytochrome c oxidase subunit VIIb 0.444
Pdhb pyruvate dehydrogenase (lipoamide) beta 0.437
Lman1 lectin, mannose-binding, 1 0.428
Anxa2 annexin A2 0.403
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.403
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.403
Rhoa ras homolog gene family, member A 0.390
Pfn1 profilin 1 0.380
Pja2 praja 2, RING-H2 motif containing 0.373
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.372
Cycs cytochrome c, somatic 0.367
Cox7c cytochrome c oxidase, subunit VIIc 0.338
Tpm4 tropomyosin 4 0.323
Rap1b RAP1B, member of RAS oncogene family 0.322
Atp5c1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.320
Cox6c cytochrome c oxidase, subunit VIc 0.308
Atp5e ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.308
Myo1c myosin IC 0.296
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.295
Mapk3 mitogen activated protein kinase 3 0.290
Atp5f1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 0.283
Tceb2 transcription elongation factor B (SIII), polypeptide 2 0.278
Acta2 smooth muscle alpha-actin 0.276
Tagln transgelin 0.270
Ndufb3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 0.266
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.253
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.250
Scarb1 scavenger receptor class B, member 1 0.250
Rab5a RAB5A, member RAS oncogene family 0.248
Fgfr1 Fibroblast growth factor receptor 1 0.244
Cfl1 cofilin 1, non-muscle 0.235
Capn2 calpain 2 0.222
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.222
Hspb1 heat shock protein 1 0.216
Myl9 myosin, light chain 9, regulatory 0.216
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.213
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.212
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.212
Anapc5 anaphase-promoting complex subunit 5 0.211
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.207
Fh1 fumarate hydratase 1 0.204
Utrn utrophin 0.193
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.190
Epas1 endothelial PAS domain protein 1 0.189
Cfp complement factor properdin 0.189
Actc1 actin, alpha, cardiac muscle 1 0.187
Myadm myeloid-associated differentiation marker 0.186
Snap25 synaptosomal-associated protein 25 0.186
Atp5o ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.184
LOC688869 similar to cytochrome c oxidase, subunit VIb polypeptide 1 0.184
Copb1 coatomer protein complex, subunit beta 1 0.178
Errfi1 ERBB receptor feedback inhibitor 1 0.177
S100a10 S100 calcium binding protein A10 0.176
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.175
Vav1 vav 1 guanine nucleotide exchange factor 0.172
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.171
Lcp1 lymphocyte cytosolic protein 1 0.171
Arhgap9 Rho GTPase activating protein 9 0.169
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.168
Cmklr1 chemokine-like receptor 1 0.168
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.166
Stip1 stress-induced phosphoprotein 1 0.163
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.162
Ripk3 receptor-interacting serine-threonine kinase 3 0.161
Clic4 chloride intracellular channel 4 0.161
Pum1 pumilio homolog 1 (Drosophila) 0.160
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.159
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.159
Itgam integrin, alpha M 0.159
Mapk8 mitogen-activated protein kinase 8 0.158
Atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.158
Syngr2 synaptogyrin 2 0.157
Casp3 caspase 3 0.155
Btk Bruton agammaglobulinemia tyrosine kinase 0.154
Cyth1 cytohesin 1 0.154
Idh3g isocitrate dehydrogenase 3 (NAD), gamma 0.154
Myo1d myosin ID 0.153
Map3k3 mitogen activated protein kinase kinase kinase 3 0.151
Pdcd10 programmed cell death 10 0.151
Tgfbr2 transforming growth factor, beta receptor II 0.150
Akt2 v-akt murine thymoma viral oncogene homolog 2 0.149
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.148
Cox5b cytochrome c oxidase subunit Vb 0.148
Cox4i1 cytochrome c oxidase subunit IV isoform 1 0.147
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.147
Gipc1 GIPC PDZ domain containing family, member 1 0.146
Barhl2 BarH-like homeobox 2 0.146
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.145
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.144
Tgfb1 transforming growth factor, beta 1 0.144