The network for 'gene silencing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gene silencing

Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HHF1 Hhf1p 0.999
SIR2 Sir2p 0.997
HHT1 Hht1p 0.996
HAT1 Hat1p 0.970
RPD3 Rpd3p 0.970
SIR4 Sir4p 0.969
SIN3 Sin3p 0.953
HDA1 Hda1p 0.951
RXT2 Rxt2p 0.948
RLF2 Rlf2p 0.938
HMO1 Hmo1p 0.925
ORC5 Orc5p 0.921
CTK1 Ctk1p 0.916
ASF1 Asf1p 0.909
SAS2 Sas2p 0.904
SET1 Set1p 0.893
YTA7 Yta7p 0.886
SDS3 Sds3p 0.858
MMS22 Mms22p 0.807
SNT1 Snt1p 0.803
SET2 Set2p 0.786
BRE1 Bre1p 0.764
SPT10 Spt10p 0.763
ORC2 Orc2p 0.745
SIR3 Sir3p 0.733
RCO1 Rco1p 0.711
NPL3 Npl3p 0.704
CYC8 Cyc8p 0.701
ARP4 Arp4p 0.691
RAP1 Rap1p 0.673
SWD1 Swd1p 0.667
HHT2 Hht2p 0.642
RTF1 Rtf1p 0.634
RSC2 Rsc2p 0.611
GCN5 Gcn5p 0.599
CTI6 Cti6p 0.580
NUP133 Nup133p 0.575
DED1 Ded1p 0.544
PUB1 Pub1p 0.542
SRM1 Srm1p 0.542
GSP1 Gsp1p 0.535
UBP8 Ubp8p 0.530
ORC1 Orc1p 0.519
CPR1 Cpr1p 0.515
IES3 Ies3p 0.504
POL2 Pol2p 0.503
POB3 Pob3p 0.493
HOS3 Hos3p 0.492
NET1 Net1p 0.490
HHO1 Hho1p 0.476
SDC1 Sdc1p 0.472
ORC6 Orc6p 0.470
CHL1 Chl1p 0.469
SPP1 Spp1p 0.468
SPT16 Spt16p 0.467
MCM3 Mcm3p 0.460
HAT2 Hat2p 0.459
TAF14 Taf14p 0.452
SPT21 Spt21p 0.448
PHO23 Pho23p 0.446
CDC6 Cdc6p 0.425
RXT3 Rxt3p 0.423
RPN4 Rpn4p 0.423
CDC45 Cdc45p 0.421
ISW2 Isw2p 0.417
SWI4 Swi4p 0.413
SSE1 Sse1p 0.408
HTB1 Htb1p 0.408
CDC14 Cdc14p 0.406
PAP2 Pap2p 0.404
YLR455W hypothetical protein 0.400
HTB2 Htb2p 0.399
SUM1 Sum1p 0.394
DPB2 Dpb2p 0.378
CDC4 Cdc4p 0.374
SLX9 Slx9p 0.372
CPR6 Cpr6p 0.357
SAS4 Sas4p 0.355
SWD3 Swd3p 0.351
HTZ1 Htz1p 0.343
NUP60 Nup60p 0.340
NTO1 Nto1p 0.334
HSP78 Hsp78p 0.332
SET3 Set3p 0.328
HHF2 Hhf2p 0.326
RSC4 Rsc4p 0.325
HST1 Hst1p 0.315
MIG2 Mig2p 0.314
RSC8 Rsc8p 0.313
CHD1 Chd1p 0.311
PHO85 Pho85p 0.309
SAS5 Sas5p 0.296
BRE2 Bre2p 0.293
PPH3 Pph3p 0.290
FUN30 Fun30p 0.288
ESF1 Esf1p 0.282
BDF1 Bdf1p 0.282
NOC3 Noc3p 0.269
AHC1 Ahc1p 0.265
NUP120 Nup120p 0.263
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
his-5 Protein HIS-5 0.733
his-1 Protein HIS-1 0.575
his-16 Protein HIS-16 0.535
attf-2 Protein ATTF-2 0.404
his-3 Protein HIS-3 0.382
his-50 Protein HIS-50 0.370
his-46 Protein HIS-46 0.344
D1081.8 Protein D1081.8 0.273
lmn-1 Protein LMN-1 0.272
his-52 Protein HIS-52 0.271
top-2 Protein TOP-2 0.264
his-62 Protein HIS-62 0.258
snr-6 Protein SNR-6 0.255
CELE_F07E5.5 Protein F07E5.5 0.252
sams-3 Protein SAMS-3 0.240
spk-1 Protein SPK-1 0.234
his-64 Protein HIS-64 0.234
his-48 Protein HIS-48 0.229
his-42 Protein HIS-42 0.228
rsp-8 Protein RSP-8 0.222
kvs-2 Protein KVS-2 0.219
his-39 Protein HIS-39 0.218
his-47 Protein HIS-47 0.216
F25H5.5 Protein F25H5.5 0.216
lin-13 Protein LIN-13 0.213
his-30 Protein HIS-30 0.203
lin-61 Protein LIN-61 0.203
hcf-1 Protein HCF-1 0.197
zyg-9 Protein ZYG-9 0.190
capg-1 Protein CAPG-1 0.187
baf-1 Protein BAF-1 0.186
mcm-7 Protein MCM-7 0.183
his-45 Protein HIS-45 0.182
cul-2 Protein CUL-2 0.177
F32E10.5 Protein F32E10.5 0.177
lin-66 Protein LIN-66 0.175
CELE_C23G10.8 Protein C23G10.8 0.171
C34F6.9 Protein C34F6.9 0.165
F56D2.6 Protein F56D2.6 0.161
teg-4 Protein TEG-4 0.157
hpo-9 Protein HPO-9 0.156
map-2 Protein MAP-2 0.154
F33H2.5 Protein F33H2.5 0.154
his-31 Protein HIS-31 0.153
CELE_Y57G11C.15 Protein Y57G11C.15 0.153
hlh-1 Protein HLH-1 0.149
hsr-9 Protein HSR-9 0.149
E02H1.1 Protein E02H1.1 0.149
his-9 Protein HIS-9 0.148
his-51 Protein HIS-51 0.148
T08B2.5 Protein T08B2.5 0.145
C24G6.8 Protein C24G6.8 0.144
wrm-1 Protein WRM-1 0.144
rfp-1 Protein RFP-1 0.143
smg-2 Protein SMG-2 0.140
kca-1 Protein KCA-1 0.138
cids-2 Protein CIDS-2 0.137
mdf-2 Protein MDF-2 0.135
him-17 Protein HIM-17 0.134
D1081.6 Protein D1081.6 0.134
mcm-4 Protein MCM-4 0.133
R05D11.4 Protein R05D11.4 0.133
tag-151 Protein TAG-151 0.133
gad-1 Protein GAD-1 0.132
ogdh-1 Protein OGDH-1 0.131
F10C2.4 Protein F10C2.4 0.129
uaf-1 Protein UAF-1 0.129
F33E11.3 Protein F33E11.3 0.129
his-29 Protein HIS-29 0.127
ncbp-2 Protein NCBP-2 0.126
kle-2 Protein KLE-2 0.125
vha-10 Protein VHA-10 0.125
aph-2 Protein APH-2 0.124
F52C12.1 Protein F52C12.1 0.124
ZC376.6 Protein ZC376.6 0.124
dnj-11 Protein DNJ-11 0.123
CELE_C24H12.5 Protein C24H12.5 0.123
klp-19 Protein KLP-19 0.122
sel-2 Protein SEL-2 0.121
tag-325 Protein TAG-325 0.121
his-4 Protein HIS-4 0.121
npp-7 Protein NPP-7 0.120
F26H9.4 Protein F26H9.4 0.120
C28H8.11 Protein C28H8.11 0.120
sig-7 Protein SIG-7 0.120
B0336.3 Protein B0336.3 0.119
dbr-1 Protein DBR-1 0.118
lin-5 Protein LIN-5 0.118
tag-353 Protein TAG-353 0.116
aspm-1 Protein ASPM-1 0.116
ect-2 Protein ECT-2 0.115
nath-10 Protein NATH-10 0.114
mig-5 Protein MIG-5 0.113
his-61 Protein HIS-61 0.113
his-15 Protein HIS-15 0.113
prp-21 Protein PRP-21 0.113
snr-5 Protein SNR-5 0.112
CELE_Y39G10AR.18 Protein Y39G10AR.18 0.112
CELE_F29C4.2 Protein F29C4.2 0.110
arp-6 Protein ARP-6 0.110
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.138
paf1 paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.128
ssrp1a structure specific recognition protein 1a 0.117
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.108
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.079
snrpa small nuclear ribonucleoprotein polypeptide A 0.072
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.064
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.059
rpa1 replication protein A1 0.054
drg1 developmentally regulated GTP binding protein 1 0.054
tcea1 transcription elongation factor A (SII), 1 0.053
fen1 flap structure-specific endonuclease 1 0.051
ahctf1 AT hook containing transcription factor 1 0.049
zgc:55876 zgc:55876 0.049
ndr1 nodal-related 1 0.049
rrm1 ribonucleotide reductase M1 polypeptide 0.049
zgc:77052 zgc:77052 0.048
wnt5b wingless-type MMTV integration site family, member 5b 0.046
snrpc small nuclear ribonucleoprotein polypeptide C 0.046
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.044
setd8b SET domain containing (lysine methyltransferase) 8b 0.042
marcksb myristoylated alanine rich protein kinase C substrate b 0.041
rbm17 RNA binding motif protein 17 0.040
hmgb1a high-mobility group box 1a 0.040
ncl nucleolin 0.037
wdr5 WD repeat domain 5 0.036
rbb4 retinoblastoma binding protein 4 0.036
ss18 synovial sarcoma translocation, chromosome 18 (H. sapiens) 0.035
nin ninein (GSK3B interacting protein) 0.033
mettl11a methyltransferase like 11A 0.033
suv39h1a suppressor of variegation 3-9 homolog 1a 0.032
sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.031
ryr1b ryanodine receptor 1b (skeletal) 0.031
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.031
pola2 polymerase (DNA directed), alpha 2 0.031
hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.030
srsf4 serine/arginine-rich splicing factor 4 0.029
gro1 groucho 1 0.029
pes pescadillo 0.029
wdr82 WD repeat domain containing 82 0.028
sox11b SRY-box containing gene 11b 0.028
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.027
suv39h1b suppressor of variegation 3-9 homolog 1b 0.027
actl6a actin-like 6A 0.027
rbmx RNA binding motif protein, X-linked 0.027
smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.026
akap12b A kinase (PRKA) anchor protein (gravin) 12b 0.026
orc5 origin recognition complex, subunit 5 0.025
setb SET translocation (myeloid leukemia-associated) B 0.025
srsf2 serine/arginine-rich splicing factor 2 0.025
zgc:113183 zgc:113183 0.025
sulf1 sulfatase 1 0.025
ewsr1b Ewing sarcoma breakpoint region 1b 0.024
cdk8 cyclin-dependent kinase 8 0.024
mapre1 microtubule-associated protein, RP/EB family, member 1 0.024
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.024
lancl1 LanC antibiotic synthetase component C-like 1 (bacterial) 0.024
ncaph non-SMC condensin I complex, subunit H 0.024
slbp stem-loop binding protein 0.023
orc1 origin recognition complex, subunit 1 0.023
ef1a elongation factor 1-alpha 0.023
gtf2a1 general transcription factor IIA, 1 0.023
dcaf7 ddb1 and cul4 associated factor 7 0.023
smyd5 SMYD family member 5 0.023
pcbp2 poly(rC) binding protein 2 0.023
scaf11 SR-related CTD-associated factor 11 0.023
ehmt2 euchromatic histone-lysine N-methyltransferase 2 0.023
polr2gl polymerase (RNA) II (DNA directed) polypeptide G-like 0.023
supt6h suppressor of Ty 6 homolog 0.022
bactin2 bactin2 0.022
rbbp6 retinoblastoma binding protein 6 0.022
btg3 B-cell translocation gene 3 0.022
cyc1 cytochrome c-1 0.022
morc2 MORC family CW-type zinc finger 2 0.021
zgc:55701 zgc:55701 0.021
fgf20a fibroblast growth factor 20a 0.021
hnrpr heterogeneous nuclear ribonucleoprotein R 0.021
hnrnpa0l heterogeneous nuclear ribonucleoprotein A0, like 0.021
stk11 serine/threonine kinase 11 0.021
zgc:101724 zgc:101724 0.021
LOC570775 protein argonaute-1-like 0.020
pola1 polymerase (DNA directed), alpha 1 0.020
tra2b transformer 2 beta homolog (Drosophila) 0.020
ints6 integrator complex subunit 6 0.020
zgc:174506 zgc:174506 0.020
usp1 ubiquitin specific protease 1 0.020
eif2c4 eukaryotic translation initiation factor 2C, 4 0.019
sf1 splicing factor 1 0.019
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.019
arpp19b cAMP-regulated phosphoprotein 19b 0.019
ruvbl2 RuvB-like 2 (E. coli) 0.019
slit1a slit homolog 1a (Drosophila) 0.019
ankrd13c ankyrin repeat domain 13C 0.019
zgc:55461 zgc:55461 0.018
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.018
lmnb1 lamin B1 0.018
rnf2 ring finger protein 2 0.018
wdr43 WD repeat domain 43 0.018
ptges prostaglandin E synthase 0.018
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.018
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CTCF CG8591 gene product from transcript CG8591-RA 1.000
esc extra sexcombs 0.996
Pcl Polycomblike 0.988
Acf1 ATP-dependent chromatin assembly factor large subunit 0.986
Pp1-87B Protein phosphatase 1 at 87B 0.974
Pc Polycomb 0.973
ash1 absent, small, or homeotic discs 1 0.968
Sir2 CG5216 gene product from transcript CG5216-RA 0.967
Su(var)3-7 Suppressor of variegation 3-7 0.966
lid little imaginal discs 0.949
pr-set7 CG3307 gene product from transcript CG3307-RC 0.949
SuUR Suppressor of Under-Replication 0.934
Rho1 CG8416 gene product from transcript CG8416-RB 0.934
piwi CG6122 gene product from transcript CG6122-RA 0.932
XNP CG4548 gene product from transcript CG4548-RA 0.932
egg eggless 0.907
gpp grappa 0.904
Snr1 Snf5-related 1 0.893
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.890
Su(var)205 Suppressor of variegation 205 0.854
E(var)3-9 Enhancer of variegation 3-9 0.854
tra transformer 0.851
wapl wings apart-like 0.824
E(z) Enhancer of zeste 0.817
D1 D1 chromosomal protein 0.809
p53 CG33336 gene product from transcript CG33336-RB 0.796
Hsc70-4 Heat shock protein cognate 4 0.796
Fmr1 CG6203 gene product from transcript CG6203-RC 0.788
B52 CG10851 gene product from transcript CG10851-RB 0.782
crm cramped 0.776
G9a CG2995 gene product from transcript CG2995-RA 0.773
CG3363 CG3363 gene product from transcript CG3363-RB 0.754
trx trithorax 0.748
AGO1 Argonaute-1 0.734
Scm Sex comb on midleg 0.705
spn-E spindle E 0.691
JIL-1 CG6297 gene product from transcript CG6297-RA 0.689
e(y)3 enhancer of yellow 3 0.689
Dp1 Dodeca-satellite-binding protein 1 0.688
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.673
CycG Cyclin G 0.668
Bap170 Brahma associated protein 170kD 0.659
vas vasa 0.650
CkIIalpha Casein kinase II alpha subunit 0.622
east enhanced adult sensory threshold 0.610
His2Av Histone H2A variant 0.609
Dcr-2 Dicer-2 0.593
aub aubergine 0.584
Caf1 Chromatin assembly factor 1 subunit 0.544
ph-d polyhomeotic distal 0.533
ball ballchen 0.530
nej nejire 0.529
Jarid2 CG3654 gene product from transcript CG3654-RD 0.527
rhi rhino 0.520
Pcaf CG4107 gene product from transcript CG4107-RA 0.514
r2d2 CG7138 gene product from transcript CG7138-RB 0.511
Moe Moesin 0.508
Spt5 CG7626 gene product from transcript CG7626-RA 0.503
zuc zucchini 0.495
mbo members only 0.491
SMC1 CG6057 gene product from transcript CG6057-RA 0.488
sxc super sex combs 0.480
Rpd3 CG7471 gene product from transcript CG7471-RA 0.477
Imp IGF-II mRNA-binding protein 0.470
Tbp TATA binding protein 0.469
mei-P26 CG12218 gene product from transcript CG12218-RA 0.458
CycB Cyclin B 0.455
hd humpty dumpty 0.453
msl-1 male-specific lethal 1 0.449
mof males absent on the first 0.442
Aos1 CG12276 gene product from transcript CG12276-RA 0.437
Dlic Dynein light intermediate chain 0.430
Mpk2 CG5475 gene product from transcript CG5475-RB 0.409
CG8165 CG8165 gene product from transcript CG8165-RA 0.404
Su(var)3-3 Suppressor of variegation 3-3 0.391
Mcm2 Minichromosome maintenance 2 0.382
Suv4-20 CG13363 gene product from transcript CG13363-RA 0.381
Pp1alpha-96A Protein phosphatase 1alpha at 96A 0.364
Parp Poly-(ADP-ribose) polymerase 0.362
Grip84 gamma-tubulin ring protein 84 0.361
CG10107 CG10107 gene product from transcript CG10107-RA 0.359
Mcm10 Sensitized chromosome inheritance modifier 19 0.358
wdb widerborst 0.356
CG16941 CG16941 gene product from transcript CG16941-RA 0.355
Sam-S S-adenosylmethionine Synthetase 0.345
CG4973 CG4973 gene product from transcript CG4973-RA 0.322
Pli Pellino 0.315
Mcm6 Minichromosome maintenance 6 0.315
Ravus CG15889 gene product from transcript CG15889-RA 0.310
Atx2 Ataxin-2 0.306
tra2 transformer 2 0.300
scny scrawny 0.296
sw short wing 0.295
Rm62 CG10279 gene product from transcript CG10279-RD 0.294
HmgD High mobility group protein D 0.292
Unc-76 CG3981 gene product from transcript CG3981-RB 0.286
Nf-YC Nuclear factor Y-box C 0.280
CtBP C-terminal Binding Protein 0.278
S6kII RPS6-protein kinase-II 0.275
Cul-5 Cullin-5 0.273
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
HDAC1 histone deacetylase 1 0.999
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.993
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.982
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.982
DICER1 dicer 1, ribonuclease type III 0.976
SP1 Sp1 transcription factor 0.971
ESR1 estrogen receptor 1 0.965
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.960
SIRT1 sirtuin 1 0.941
MBD1 methyl-CpG binding domain protein 1 0.936
PCGF2 polycomb group ring finger 2 0.921
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.915
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.888
BMI1 BMI1 polycomb ring finger oncogene 0.886
SRSF2 serine/arginine-rich splicing factor 2 0.880
YY1 YY1 transcription factor 0.876
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.874
TNRC6A trinucleotide repeat containing 6A 0.865
EP300 E1A binding protein p300 0.852
PARP1 poly (ADP-ribose) polymerase 1 0.850
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.845
RING1 ring finger protein 1 0.839
EED embryonic ectoderm development 0.838
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.838
ACTL6A actin-like 6A 0.821
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.794
RUVBL1 RuvB-like 1 (E. coli) 0.785
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.781
HDAC2 histone deacetylase 2 0.762
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.731
TP53 tumor protein p53 0.730
HIST1H3D histone cluster 1, H3d 0.724
CBX1 chromobox homolog 1 0.721
SUZ12 suppressor of zeste 12 homolog (Drosophila) 0.719
RBBP4 retinoblastoma binding protein 4 0.719
TNRC6B trinucleotide repeat containing 6B 0.681
CBX5 chromobox homolog 5 0.676
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.673
PABPC1 poly(A) binding protein, cytoplasmic 1 0.663
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.649
SF1 splicing factor 1 0.606
HIST1H2AE histone cluster 1, H2ae 0.604
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.595
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.577
CBX8 chromobox homolog 8 0.567
HIST2H2BE histone cluster 2, H2be 0.556
HIST1H2BG histone cluster 1, H2bg 0.553
HIST1H3B histone cluster 1, H3b 0.551
TRIM28 tripartite motif containing 28 0.542
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.474
USP11 ubiquitin specific peptidase 11 0.473
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.469
MCM2 minichromosome maintenance complex component 2 0.457
PHC2 polyhomeotic homolog 2 (Drosophila) 0.447
HIST1H2BI histone cluster 1, H2bi 0.436
CDK2 cyclin-dependent kinase 2 0.429
HIST1H1C histone cluster 1, H1c 0.427
PCNA proliferating cell nuclear antigen 0.411
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.394
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.394
H2AFX H2A histone family, member X 0.394
SSRP1 structure specific recognition protein 1 0.363
HIST2H3C histone cluster 2, H3c 0.342
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 0.334
ADNP activity-dependent neuroprotector homeobox 0.330
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.328
SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.327
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.326
SMAD3 SMAD family member 3 0.323
HIST1H2AJ histone cluster 1, H2aj 0.315
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.308
HIST1H4A histone cluster 1, H4a 0.301
WDR5 WD repeat domain 5 0.295
SMAD4 SMAD family member 4 0.287
HIST1H2BD histone cluster 1, H2bd 0.286
RB1 retinoblastoma 1 0.284
SRSF7 serine/arginine-rich splicing factor 7 0.279
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.274
CHD4 chromodomain helicase DNA binding protein 4 0.272
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.271
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.260
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.257
CBX4 chromobox homolog 4 0.256
MBD3 methyl-CpG binding domain protein 3 0.255
EIF2C4 eukaryotic translation initiation factor 2C, 4 0.251
DAXX death-domain associated protein 0.244
HIST1H2AC histone cluster 1, H2ac 0.240
HIST1H2AM histone cluster 1, H2am 0.232
RNF2 ring finger protein 2 0.231
RBM10 RNA binding motif protein 10 0.228
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.227
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.219
HIST1H4H histone cluster 1, H4h 0.217
HIST1H2BE histone cluster 1, H2be 0.206
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.197
HDAC3 histone deacetylase 3 0.196
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.193
TOP2B topoisomerase (DNA) II beta 180kDa 0.189
KAT5 K(lysine) acetyltransferase 5 0.188
HIST1H4D histone cluster 1, H4d 0.187
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Rnf2 ring finger protein 2 0.997
Pou5f1 POU domain, class 5, transcription factor 1 0.994
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.975
Nanog Nanog homeobox 0.959
Hdac1 histone deacetylase 1 0.942
Rybp RING1 and YY1 binding protein 0.940
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.938
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.935
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.918
Hdac2 histone deacetylase 2 0.914
Pcgf2 polycomb group ring finger 2 0.901
Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.885
Ctcf CCCTC-binding factor 0.873
Arid1b AT rich interactive domain 1B (SWI-like) 0.872
H3f3a H3 histone, family 3A 0.836
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.827
Arid1a AT rich interactive domain 1A (SWI-like) 0.801
Phc2 polyhomeotic-like 2 (Drosophila) 0.779
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.768
Polr2a polymerase (RNA) II (DNA directed) polypeptide A 0.759
Sin3a transcriptional regulator, SIN3A (yeast) 0.734
Tapbp TAP binding protein 0.688
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.680
Ep300 E1A binding protein p300 0.669
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.642
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.636
Lbr lamin B receptor 0.632
Bmi1 Bmi1 polycomb ring finger oncogene 0.631
Phc1 polyhomeotic-like 1 (Drosophila) 0.622
Dnmt3a DNA methyltransferase 3A 0.621
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.609
Srsf1 serine/arginine-rich splicing factor 1 0.598
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.563
Ccna2 cyclin A2 0.558
Trim28 tripartite motif-containing 28 0.544
Cbx2 chromobox homolog 2 (Drosophila Pc class) 0.541
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.536
Wdr5 WD repeat domain 5 0.534
Mta2 metastasis-associated gene family, member 2 0.534
Cdk1 cyclin-dependent kinase 1 0.514
Yy1 YY1 transcription factor 0.488
Trp53 transformation related protein 53 0.482
Dnmt3b DNA methyltransferase 3B 0.482
Hmgb1 high mobility group box 1 0.476
E2f1 E2F transcription factor 1 0.476
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.449
Smc3 structural maintenace of chromosomes 3 0.446
Tcfcp2l1 transcription factor CP2-like 1 0.442
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.428
Brd8 bromodomain containing 8 0.427
Mga MAX gene associated 0.424
Ep400 E1A binding protein p400 0.418
Matr3 matrin 3 0.413
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.399
Tnrc6b trinucleotide repeat containing 6b 0.394
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.393
Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 0.387
Lmnb1 lamin B1 0.374
Map3k1 mitogen-activated protein kinase kinase kinase 1 0.373
Dek DEK oncogene (DNA binding) 0.362
Cdk2 cyclin-dependent kinase 2 0.359
Crebbp CREB binding protein 0.358
Ehmt1 euchromatic histone methyltransferase 1 0.344
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.342
Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.339
Tfdp1 transcription factor Dp 1 0.330
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.323
Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 0.312
H2afx H2A histone family, member X 0.310
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.306
Pcgf6 polycomb group ring finger 6 0.304
Rbbp4 retinoblastoma binding protein 4 0.301
Cbx8 chromobox homolog 8 (Drosophila Pc class) 0.296
Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 0.283
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.275
Zmym5 zinc finger, MYM-type 5 0.275
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.271
Brca1 breast cancer 1 0.270
Sox2 SRY-box containing gene 2 0.264
Eif2c1 eukaryotic translation initiation factor 2C, 1 0.261
Cdk4 cyclin-dependent kinase 4 0.258
Ncaph non-SMC condensin I complex, subunit H 0.258
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.253
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.247
Bptf bromodomain PHD finger transcription factor 0.245
Zfp362 zinc finger protein 362 0.244
Uba2 ubiquitin-like modifier activating enzyme 2 0.243
Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 0.241
Btg1 B-cell translocation gene 1, anti-proliferative 0.240
Cnot6 CCR4-NOT transcription complex, subunit 6 0.238
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.234
Mbtd1 mbt domain containing 1 0.234
Mael maelstrom homolog (Drosophila) 0.233
Brca2 breast cancer 2 0.232
Rsf1 remodeling and spacing factor 1 0.232
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.225
Mta1 metastasis associated 1 0.222
Lef1 lymphoid enhancer binding factor 1 0.219
Mybbp1a MYB binding protein (P160) 1a 0.214
Stag1 stromal antigen 1 0.213
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism