The network for 'rna dependent dna replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rna dependent dna replication

A DNA replication process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.

Name Description Probability Func Analog Organism
CDC13 Cdc13p 0.931
POL1 Pol1p 0.735
RFA2 Rfa2p 0.666
RFA1 Rfa1p 0.625
EST2 Est2p 0.499
POL12 Pol12p 0.459
EST1 Est1p 0.390
RAD53 Rad53p 0.303
TEN1 Ten1p 0.252
NOP10 Nop10p 0.222
RAD5 Rad5p 0.214
POL32 Pol32p 0.192
SMC6 Smc6p 0.150
POL2 Pol2p 0.146
DNA2 Dna2p 0.135
DUN1 Dun1p 0.108
RIF1 Rif1p 0.103
POL3 Pol3p 0.103
RAD27 Rad27p 0.098
CSM3 Csm3p 0.096
MSH6 Msh6p 0.092
MEC1 Mec1p 0.082
PRI2 Pri2p 0.073
STI1 Sti1p 0.071
POL30 Pol30p 0.068
CDC9 Cdc9p 0.066
SGS1 Sgs1p 0.066
PRI1 Pri1p 0.065
PIF1 Pif1p 0.064
STN1 Stn1p 0.063
GAR1 Gar1p 0.051
YDL156W hypothetical protein 0.049
MRC1 Mrc1p 0.047
RFA3 Rfa3p 0.046
NOP6 Nop6p 0.043
YLR162W hypothetical protein 0.040
PSF1 Psf1p 0.039
VAC17 Vac17p 0.039
MGS1 Mgs1p 0.038
TOP3 Top3p 0.038
YBL081W hypothetical protein 0.038
REV1 Rev1p 0.037
RAD55 Rad55p 0.037
MSH3 Msh3p 0.037
RAD51 Rad51p 0.036
PDS1 Pds1p 0.033
YLR363W-A hypothetical protein 0.032
DPB2 Dpb2p 0.032
ARP10 Arp10p 0.030
SRD1 Srd1p 0.029
YOR390W hypothetical protein 0.029
HHO1 Hho1p 0.028
RIO1 Rio1p 0.028
URA3 Ura3p 0.028
LEU2 Leu2p 0.028
YLR264C-A hypothetical protein 0.028
RMI1 Rmi1p 0.027
URB2 Urb2p 0.027
PRS2 Prs2p 0.026
THG1 Thg1p 0.026
QRI1 Qri1p 0.026
ADH2 Adh2p 0.026
RTT105 Rtt105p 0.025
YOL038C-A hypothetical protein 0.025
MER1 Mer1p 0.024
YNR071C hypothetical protein 0.024
ORC2 Orc2p 0.023
EXO1 Exo1p 0.023
BRL1 Brl1p 0.023
PRP31 Prp31p 0.023
HO Hop 0.023
ZPS1 Zps1p 0.023
RRP36 Rrp36p 0.023
TEL2 Tel2p 0.023
EBS1 Ebs1p 0.022
FUR4 Fur4p 0.022
GPI13 Gpi13p 0.022
HCH1 Hch1p 0.022
YAR068W hypothetical protein 0.022
HXT3 Hxt3p 0.022
TOF1 Tof1p 0.022
ELG1 Elg1p 0.022
MCM10 Mcm10p 0.021
YML053C hypothetical protein 0.021
CDC21 Cdc21p 0.021
GYL1 Gyl1p 0.021
ALG14 Alg14p 0.021
BUB1 Bub1p 0.021
YLR042C hypothetical protein 0.021
CUP1-1 Cup1-1p 0.021
SWC7 Swc7p 0.021
CAB4 Cab4p 0.020
YJR129C hypothetical protein 0.020
YPR157W hypothetical protein 0.020
HST3 Hst3p 0.020
REE1 Ree1p 0.020
ATP6 Atp6p 0.020
ARG8 Arg8p 0.020
RNH201 Rnh201p 0.020
SWM2 Swm2p 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
cku-70 Protein CKU-70 0.025
cel-1 Protein CEL-1 0.021
CELE_C01G10.8 Protein C01G10.8 0.020
rpn-3 Protein RPN-3 0.019
rad-23 Protein RAD-23 0.019
C35A5.8 Protein C35A5.8 0.018
mat-2 Protein MAT-2 0.016
csn-1 Protein CSN-1 0.014
mus-101 Protein MUS-101 0.014
dnj-12 Protein DNJ-12 0.013
C37A5.7 Protein C37A5.7 0.013
T23G4.3 Protein T23G4.3 0.013
drh-3 Protein DRH-3 0.013
Y34D9A.3 Protein Y34D9A.3 0.013
R11A8.2 Protein R11A8.2 0.012
smo-1 Protein SMO-1 0.011
rpt-3 Protein RPT-3 0.011
tba-2 Protein TBA-2 0.011
mms-19 Protein MMS-19 0.011
rod-1 Protein ROD-1 0.011
dpf-3 Protein DPF-3 0.010
sqv-4 Protein SQV-4 0.010
lbp-9 Protein LBP-9 0.010
ZK632.2 Protein ZK632.2 0.010
F08B4.3 Protein F08B4.3 0.010
C01H6.9 Protein C01H6.9 0.010
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Danio rerio
Name Description Probability Func Analog Organism
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.055
tp53 tumor protein p53 0.019
hells helicase, lymphoid-specific 0.018
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.996
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.783
ACD adrenocortical dysplasia homolog (mouse) 0.420
BLM Bloom syndrome, RecQ helicase-like 0.386
RPA2 replication protein A2, 32kDa 0.377
NBN nibrin 0.266
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.264
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.240
TERF2 telomeric repeat binding factor 2 0.240
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.227
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.217
TERF2IP telomeric repeat binding factor 2, interacting protein 0.160
SMC1A structural maintenance of chromosomes 1A 0.158
RFC1 replication factor C (activator 1) 1, 145kDa 0.154
ATM ataxia telangiectasia mutated 0.096
RPA1 replication protein A1, 70kDa 0.095
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.091
PPID peptidylprolyl isomerase D 0.091
RPA3 replication protein A3, 14kDa 0.081
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.074
ORC2 origin recognition complex, subunit 2 0.067
WRN Werner syndrome, RecQ helicase-like 0.060
FANCD2 Fanconi anemia, complementation group D2 0.054
ORC1 origin recognition complex, subunit 1 0.048
HUS1 HUS1 checkpoint homolog (S. pombe) 0.047
MDC1 mediator of DNA-damage checkpoint 1 0.047
STAG1 stromal antigen 1 0.031
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.028
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.027
POT1 protection of telomeres 1 homolog (S. pombe) 0.025
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.024
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.024
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) 0.024
CDK2 cyclin-dependent kinase 2 0.023
TGIF1 TGFB-induced factor homeobox 1 0.019
TOP3A topoisomerase (DNA) III alpha 0.016
FNBP1 formin binding protein 1 0.015
HSPH1 heat shock 105kDa/110kDa protein 1 0.015
MAPK7 mitogen-activated protein kinase 7 0.014
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.014
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.013
DAXX death-domain associated protein 0.013
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.012
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.011
PARP1 poly (ADP-ribose) polymerase 1 0.011
SMG6 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.011
UNG uracil-DNA glycosylase 0.011
BANP BTG3 associated nuclear protein 0.011
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.827
Timeless timeless homolog (Drosophila) 0.800
Trp53 transformation related protein 53 0.795
Prim1 DNA primase, p49 subunit 0.630
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.447
Nap1l1 nucleosome assembly protein 1-like 1 0.393
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.291
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.247
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.209
Prim2 DNA primase, p58 subunit 0.202
Rfc1 replication factor C (activator 1) 1 0.194
Nup85 nucleoporin 85 0.184
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.168
Hspa8 heat shock protein 8 0.158
Stip1 stress-induced phosphoprotein 1 0.123
Hsph1 heat shock 105kDa/110kDa protein 1 0.115
Rrm1 ribonucleotide reductase M1 0.111
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.108
Set SET nuclear oncogene 0.091
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.090
Skil SKI-like 0.089
Wrn Werner syndrome homolog (human) 0.088
Parp1 poly (ADP-ribose) polymerase family, member 1 0.084
Pola2 polymerase (DNA directed), alpha 2 0.072
Terf1 telomeric repeat binding factor 1 0.071
Smn1 survival motor neuron 1 0.071
Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 0.066
Dnajc9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.066
Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.065
Tipin timeless interacting protein 0.064
Cacybp calcyclin binding protein 0.062
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.062
Mdm4 transformed mouse 3T3 cell double minute 4 0.056
Msh2 mutS homolog 2 (E. coli) 0.053
Rpa2 replication protein A2 0.051
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.050
Lig1 ligase I, DNA, ATP-dependent 0.050
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.049
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.044
Dkc1 dyskeratosis congenita 1, dyskerin homolog (human) 0.043
Ruvbl2 RuvB-like protein 2 0.041
Hmgb1 high mobility group box 1 0.040
Tubg1 tubulin, gamma 1 0.039
Smc2 structural maintenance of chromosomes 2 0.039
Igh immunoglobulin heavy chain complex 0.038
Daxx Fas death domain-associated protein 0.038
Pot1a protection of telomeres 1A 0.037
Pold3 polymerase (DNA-directed), delta 3, accessory subunit 0.037
Kpnb1 karyopherin (importin) beta 1 0.034
Ttn titin 0.032
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.031
Fkbp4 FK506 binding protein 4 0.030
Sae1 SUMO1 activating enzyme subunit 1 0.028
Rfc4 replication factor C (activator 1) 4 0.028
Vcp valosin containing protein 0.027
Tdp1 tyrosyl-DNA phosphodiesterase 1 0.027
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.027
Nup93 nucleoporin 93 0.026
Hspa5 heat shock protein 5 0.026
Acd adrenocortical dysplasia 0.026
Dtymk deoxythymidylate kinase 0.026
Haus6 HAUS augmin-like complex, subunit 6 0.026
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.025
Iqcb1 IQ calmodulin-binding motif containing 1 0.025
Eftud2 elongation factor Tu GTP binding domain containing 2 0.025
Mlh1 mutL homolog 1 (E. coli) 0.022
Hspd1 heat shock protein 1 (chaperonin) 0.022
Rfc3 replication factor C (activator 1) 3 0.022
Nphp1 nephronophthisis 1 (juvenile) homolog (human) 0.022
Smc4 structural maintenance of chromosomes 4 0.021
Fen1 flap structure specific endonuclease 1 0.021
Lin9 lin-9 homolog (C. elegans) 0.021
Thoc4 THO complex 4 0.021
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.021
Tubgcp2 tubulin, gamma complex associated protein 2 0.021
Pms2 postmeiotic segregation increased 2 (S. cerevisiae) 0.020
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.020
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.020
Zc3hc1 zinc finger, C3HC type 1 0.020
Aaas achalasia, adrenocortical insufficiency, alacrimia 0.020
Uba2 ubiquitin-like modifier activating enzyme 2 0.020
Gart phosphoribosylglycinamide formyltransferase 0.019
0610010K14Rik RIKEN cDNA 0610010K14 gene 0.019
Cbx5 chromobox homolog 5 (Drosophila HP1a) 0.019
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.019
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.019
Pcna proliferating cell nuclear antigen 0.018
Ikbkb inhibitor of kappaB kinase beta 0.018
Hells helicase, lymphoid specific 0.018
Dna2 DNA replication helicase 2 homolog (yeast) 0.018
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.018
Ints9 integrator complex subunit 9 0.017
Ifrd2 interferon-related developmental regulator 2 0.017
Tmpo thymopoietin 0.017
Gja1 gap junction protein, alpha 1 0.017
Snrpb small nuclear ribonucleoprotein B 0.017
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.017
Rpgrip1l Rpgrip1-like 0.016
Etaa1 Ewing's tumor-associated antigen 1 0.016
Ilf2 interleukin enhancer binding factor 2 0.016
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Rattus norvegicus
Name Description Probability Func Analog Organism