The network for 'mitotic chromosome condensation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitotic chromosome condensation

The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.

Name Description Probability Func Analog Organism
SMC4 Smc4p 0.971
SMC2 Smc2p 0.820
YCS4 Ycs4p 0.809
SMC3 Smc3p 0.735
YCG1 Ycg1p 0.664
BRN1 Brn1p 0.514
SMC1 Smc1p 0.507
PDS5 Pds5p 0.307
IRR1 Irr1p 0.220
SLK19 Slk19p 0.192
SCC2 Scc2p 0.075
POL2 Pol2p 0.044
ESC8 Esc8p 0.029
ALT2 Alt2p 0.028
TOF2 Tof2p 0.028
GEA2 Gea2p 0.026
SCC4 Scc4p 0.024
SRD1 Srd1p 0.024
SPO16 Spo16p 0.023
LEU2 Leu2p 0.022
YLR162W hypothetical protein 0.022
YLR264C-A hypothetical protein 0.022
RFC3 Rfc3p 0.020
MER1 Mer1p 0.020
YOL038C-A hypothetical protein 0.020
STU1 Stu1p 0.018
ARG8 Arg8p 0.018
HO Hop 0.018
YAR068W hypothetical protein 0.018
ARP10 Arp10p 0.017
YLR042C hypothetical protein 0.017
COS12 Cos12p 0.017
SPC97 Spc97p 0.016
POL3 Pol3p 0.016
YPR157W hypothetical protein 0.016
ORC1 Orc1p 0.016
ATP6 Atp6p 0.016
NUF2 Nuf2p 0.015
USO1 Uso1p 0.015
CUP1-1 Cup1-1p 0.015
SPL2 Spl2p 0.015
CHL1 Chl1p 0.015
RDH54 Rdh54p 0.015
YIR035C hypothetical protein 0.015
CBF2 Cbf2p 0.015
ESP1 Esp1p 0.015
ORC5 Orc5p 0.014
AUA1 Aua1p 0.014
RFC5 Rfc5p 0.014
SLI15 Sli15p 0.014
SPC42 Spc42p 0.014
URA3 Ura3p 0.014
HPF1 Hpf1p 0.014
FMT1 Fmt1p 0.014
ZPS1 Zps1p 0.014
YBR013C hypothetical protein 0.014
BSC1 Bsc1p 0.014
YOL013W-A hypothetical protein 0.013
HXT3 Hxt3p 0.013
KIP1 Kip1p 0.013
IZH4 Izh4p 0.013
RAD53 Rad53p 0.012
MIF2 Mif2p 0.012
SCM4 Scm4p 0.012
YLR040C hypothetical protein 0.012
GYL1 Gyl1p 0.012
SMC6 Smc6p 0.012
SPS4 Sps4p 0.012
YPR096C hypothetical protein 0.012
YJL181W hypothetical protein 0.012
ADH2 Adh2p 0.012
MF(ALPHA)2 Mf(alpha)2p 0.012
CPD1 Cpd1p 0.011
CSM3 Csm3p 0.011
YPL067C hypothetical protein 0.011
SGO1 Sgo1p 0.011
MF(ALPHA)1 Mf(alpha)1p 0.011
YAR066W hypothetical protein 0.011
YAL037C-A hypothetical protein 0.011
RNP1 Rnp1p 0.011
CTF3 Ctf3p 0.011
OPT2 Opt2p 0.011
DIC1 Dic1p 0.011
NRG2 Nrg2p 0.011
UPS3 Ups3p 0.011
PDS1 Pds1p 0.011
SWC7 Swc7p 0.011
YGR035C hypothetical protein 0.010
NSE4 Nse4p 0.010
YAL064W hypothetical protein 0.010
YGL006W-A hypothetical protein 0.010
YIL151C hypothetical protein 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
prg-2 Protein PRG-2 0.055
glh-4 Protein GLH-4 0.030
dao-5 Protein DAO-5 0.029
mel-28 Protein MEL-28 0.029
wrm-1 Protein WRM-1 0.029
aspm-1 Protein ASPM-1 0.026
mcm-3 Protein MCM-3 0.022
mcm-7 Protein MCM-7 0.021
mcm-2 Protein MCM-2 0.020
rod-1 Protein ROD-1 0.020
ppw-2 Protein PPW-2 0.019
R05H10.3 Protein R05H10.3 0.019
klp-18 Protein KLP-18 0.018
rad-50 Protein RAD-50 0.018
R11A8.7 Protein R11A8.7 0.017
hsr-9 Protein HSR-9 0.017
zyg-9 Protein ZYG-9 0.017
dsh-2 Protein DSH-2 0.017
F31C3.3 Protein F31C3.3 0.017
CELE_Y48B6A.1 Protein Y48B6A.1 0.016
ttll-5 Protein TTLL-5 0.016
glh-1 Protein GLH-1 0.016
mcm-4 Protein MCM-4 0.016
F33H2.3 Protein F33H2.3 0.016
CELE_T02C12.3 Protein T02C12.3 0.016
mcm-5 Protein MCM-5 0.015
M57.1 Protein M57.1 0.015
K06A5.1 Protein K06A5.1 0.015
C18A3.3 Protein C18A3.3 0.014
csr-1 Protein CSR-1 0.014
hpo-32 Protein HPO-32 0.014
bub-1 Protein BUB-1 0.014
T12F5.2 Protein T12F5.2 0.014
ucr-2.3 Protein UCR-2.3 0.014
knl-1 Protein KNL-1 0.014
got-2.1 Protein GOT-2.1 0.013
acs-4 Protein ACS-4 0.013
F33H2.5 Protein F33H2.5 0.013
pqn-65 Protein PQN-65 0.013
nmy-2 Protein NMY-2 0.013
F32E10.5 Protein F32E10.5 0.013
xpo-2 Protein XPO-2 0.013
swsn-7 Protein SWSN-7 0.013
CELE_Y75B8A.25 Protein Y75B8A.25 0.012
plk-3 Protein PLK-3 0.012
rpl-11.1 Protein RPL-11.1 0.012
air-2 Protein AIR-2 0.012
C30G12.6 Protein C30G12.6 0.012
hpo-40 Protein HPO-40 0.012
set-16 Protein SET-16 0.012
unc-89 Protein UNC-89 0.012
klp-19 Protein KLP-19 0.012
inx-21 Protein INX-21 0.012
cbd-1 Protein CBD-1 0.012
Y47D3A.29 Protein Y47D3A.29 0.012
cin-4 Protein CIN-4 0.011
C53H9.2 Protein C53H9.2 0.011
npp-6 Protein NPP-6 0.011
F10B5.2 Protein F10B5.2 0.011
Y4C6B.1 Protein Y4C6B.1 0.011
C46A5.6 Protein C46A5.6 0.011
pgl-1 Protein PGL-1 0.011
cpb-1 Protein CPB-1 0.011
hcp-1 Protein HCP-1 0.011
rsa-1 Protein RSA-1 0.011
F54E12.2 Protein F54E12.2 0.010
CELE_F23C8.9 Protein F23C8.9 0.010
klp-15 Protein KLP-15 0.010
pdp-1 Protein PDP-1 0.010
cgh-1 Protein CGH-1 0.010
sna-2 Protein SNA-2 0.010
scc-3 Protein SCC-3 0.010
cdc-48.1 Protein CDC-48.1 0.010
rpn-2 Protein RPN-2 0.010
T07A9.14 Protein T07A9.14 0.010
hcp-2 Protein HCP-2 0.010
T08G11.4 Protein T08G11.4 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Orc2 Origin recognition complex subunit 2 0.988
RfC4 Replication factor C subunit 4 0.889
asp abnormal spindle 0.827
mus209 mutagen-sensitive 209 0.795
Cap-G CG34438 gene product from transcript CG34438-RF 0.698
ball ballchen 0.624
barr barren 0.618
dpa disc proliferation abnormal 0.598
Klp61F Kinesin-like protein at 61F 0.589
gwl greatwall 0.507
BubR1 Bub1-related kinase 0.475
pav pavarotti 0.416
l(1)dd4 lethal (1) discs degenerate 4 0.412
SMC2 CG10212 gene product from transcript CG10212-RA 0.394
woc without children 0.367
pita CG3941 gene product from transcript CG3941-RA 0.338
dup double parked 0.301
egg eggless 0.294
Cenp-C CG31258 gene product from transcript CG31258-RA 0.286
Incenp Inner centromere protein 0.257
Su(var)205 Suppressor of variegation 205 0.241
vtd verthandi 0.238
mars CG17064 gene product from transcript CG17064-RB 0.236
ncd non-claret disjunctional 0.232
Orc5 Origin recognition complex subunit 5 0.211
CG13350 CG13350 gene product from transcript CG13350-RA 0.210
Ndc80 CG9938 gene product from transcript CG9938-RA 0.207
otu ovarian tumor 0.194
cmet CENP-meta 0.175
cav caravaggio 0.171
polo CG12306 gene product from transcript CG12306-RA 0.154
Mcm10 Sensitized chromosome inheritance modifier 19 0.151
jumu jumeau 0.142
Spc25 CG7242 gene product from transcript CG7242-RA 0.140
hd humpty dumpty 0.137
piwi CG6122 gene product from transcript CG6122-RA 0.133
Su(var)2-10 Suppressor of variegation 2-10 0.133
CycB Cyclin B 0.130
ash1 absent, small, or homeotic discs 1 0.130
swa swallow 0.125
CycB3 Cyclin B3 0.118
Spc105R Spc105-related 0.116
Klp67A Kinesin-like protein at 67A 0.111
pzg putzig 0.107
NiPp1 Nuclear inhibitor of Protein phosphatase 1 0.103
stg string 0.091
Sse Separase 0.088
aub aubergine 0.084
Mcm6 Minichromosome maintenance 6 0.080
Klp3A Kinesin-like protein at 3A 0.079
mrn marionette 0.077
mael maelstrom 0.076
msl-3 male-specific lethal 3 0.074
spn-E spindle E 0.069
Orc1 Origin recognition complex subunit 1 0.065
Cdc27 CG8610 gene product from transcript CG8610-RA 0.064
vas vasa 0.064
cid centromere identifier 0.063
Su(var)3-7 Suppressor of variegation 3-7 0.056
Sas-4 CG10061 gene product from transcript CG10061-RA 0.055
pds5 CG17509 gene product from transcript CG17509-RA 0.055
neb nebbish 0.053
lat latheo 0.053
Dhc64C Dynein heavy chain 64C 0.052
Slbp Stem-loop binding protein 0.049
Mcm5 Minichromosome maintenance 5 0.049
mus101 mutagen-sensitive 101 0.048
SuUR Suppressor of Under-Replication 0.046
tum tumbleweed 0.045
rod rough deal 0.044
zpg zero population growth 0.044
kis kismet 0.043
stwl stonewall 0.042
Rpd3 CG7471 gene product from transcript CG7471-RA 0.042
Su(z)2 Suppressor of zeste 2 0.041
wisp wispy 0.040
mus301 mutagen-sensitive 301 0.038
MBD-like CG8208 gene product from transcript CG8208-RA 0.038
Orc6 Origin recognition complex subunit 6 0.037
RhoGAP54D CG6477 gene product from transcript CG6477-RA 0.036
Caf1-105 CG12892 gene product from transcript CG12892-RA 0.034
mxc multi sex combs 0.033
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.032
Hmr Hybrid male rescue 0.032
Klp10A CG1453 gene product from transcript CG1453-RA 0.031
pim pimples 0.031
cnn centrosomin 0.031
orb oo18 RNA-binding protein 0.029
His2Av Histone H2A variant 0.029
png pan gu 0.028
Suv4-20 CG13363 gene product from transcript CG13363-RA 0.028
SmD3 Small ribonucleoprotein particle protein SmD3 0.027
Nek2 CG17256 gene product from transcript CG17256-RA 0.027
Su(var)3-3 Suppressor of variegation 3-3 0.027
sub subito 0.026
SelD Selenide,water dikinase 0.026
Mcm2 Minichromosome maintenance 2 0.026
esc extra sexcombs 0.026
JIL-1 CG6297 gene product from transcript CG6297-RA 0.025
Cdc37 CG12019 gene product from transcript CG12019-RA 0.025
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Homo sapiens
Name Description Probability Func Analog Organism
SMC4 structural maintenance of chromosomes 4 0.925
NCAPD2 non-SMC condensin I complex, subunit D2 0.889
NCAPH non-SMC condensin I complex, subunit H 0.786
NCAPG non-SMC condensin I complex, subunit G 0.705
ORC4 origin recognition complex, subunit 4 0.682
SMC2 structural maintenance of chromosomes 2 0.580
RAD21 RAD21 homolog (S. pombe) 0.225
NCAPH2 non-SMC condensin II complex, subunit H2 0.217
ORC1 origin recognition complex, subunit 1 0.098
TRIP6 thyroid hormone receptor interactor 6 0.091
ORC3 origin recognition complex, subunit 3 0.062
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.037
NCAPG2 non-SMC condensin II complex, subunit G2 0.037
PARP1 poly (ADP-ribose) polymerase 1 0.033
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.029
TOP2A topoisomerase (DNA) II alpha 170kDa 0.028
CKAP5 cytoskeleton associated protein 5 0.027
BIRC5 baculoviral IAP repeat containing 5 0.021
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.020
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.020
RACGAP1 Rac GTPase activating protein 1 0.019
MKI67 antigen identified by monoclonal antibody Ki-67 0.019
KIF20A kinesin family member 20A 0.018
CDCA8 cell division cycle associated 8 0.016
TACC3 transforming, acidic coiled-coil containing protein 3 0.015
SFPQ splicing factor proline/glutamine-rich 0.015
KIF11 kinesin family member 11 0.014
GPSM2 G-protein signaling modulator 2 0.013
CDK1 cyclin-dependent kinase 1 0.013
LBR lamin B receptor 0.012
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 0.011
AURKA aurora kinase A 0.011
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.010
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Hoxa10 homeobox A10 1.000
Hoxa9 homeobox A9 0.998
Hoxd10 homeobox D10 0.994
Hoxc10 homeobox C10 0.976
Prc1 protein regulator of cytokinesis 1 0.955
Ccnb1 cyclin B1 0.890
Ccna2 cyclin A2 0.859
Cdk1 cyclin-dependent kinase 1 0.779
Hoxd9 homeobox D9 0.657
Plk4 polo-like kinase 4 (Drosophila) 0.655
Hoxd8 homeobox D8 0.629
Kif11 kinesin family member 11 0.604
Hoxd3 homeobox D3 0.604
Hoxc8 homeobox C8 0.589
Cdc7 cell division cycle 7 (S. cerevisiae) 0.547
Kif2c kinesin family member 2C 0.541
2810417H13Rik RIKEN cDNA 2810417H13 gene 0.540
Hoxb9 homeobox B9 0.538
Anln anillin, actin binding protein 0.498
Ckap2 cytoskeleton associated protein 2 0.471
Pnn pinin 0.470
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.462
Plk1 polo-like kinase 1 (Drosophila) 0.424
Ncaph non-SMC condensin I complex, subunit H 0.405
Kif4 kinesin family member 4 0.388
Tcf12 transcription factor 12 0.383
Nkx3-1 NK-3 transcription factor, locus 1 (Drosophila) 0.382
Cdca8 cell division cycle associated 8 0.373
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.333
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.329
Haus3 HAUS augmin-like complex, subunit 3 0.329
Chek2 CHK2 checkpoint homolog (S. pombe) 0.319
Iqgap3 IQ motif containing GTPase activating protein 3 0.290
Kif22 kinesin family member 22 0.287
Cenpk centromere protein K 0.286
Top2a topoisomerase (DNA) II alpha 0.271
Ttk Ttk protein kinase 0.261
Kif20a kinesin family member 20A 0.251
Meis1 Meis homeobox 1 0.247
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.224
Aurkb aurora kinase B 0.221
Aurka aurora kinase A 0.206
Dtl denticleless homolog (Drosophila) 0.203
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.186
Mis18bp1 MIS18 binding protein 1 0.178
Mael maelstrom homolog (Drosophila) 0.172
Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.171
Parp2 poly (ADP-ribose) polymerase family, member 2 0.166
Trim59 tripartite motif-containing 59 0.163
Hoxc4 homeobox C4 0.159
Upf3b UPF3 regulator of nonsense transcripts homolog B (yeast) 0.158
Mxd3 Max dimerization protein 3 0.153
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.152
Hoxa11 homeobox A11 0.151
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.150
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.149
Tcf19 transcription factor 19 0.148
Gtse1 G two S phase expressed protein 1 0.147
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.147
Fam64a family with sequence similarity 64, member A 0.126
Gmnn geminin 0.125
Myef2 myelin basic protein expression factor 2, repressor 0.123
Orc4 origin recognition complex, subunit 4 0.121
Kif23 kinesin family member 23 0.119
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.116
Smc2 structural maintenance of chromosomes 2 0.114
Cdkn3 cyclin-dependent kinase inhibitor 3 0.114
Tacc3 transforming, acidic coiled-coil containing protein 3 0.110
E2f1 E2F transcription factor 1 0.109
Rad51ap1 RAD51 associated protein 1 0.107
Cdt1 chromatin licensing and DNA replication factor 1 0.105
Gsg2 germ cell-specific gene 2 0.103
Mybl2 myeloblastosis oncogene-like 2 0.103
Incenp inner centromere protein 0.102
Hmgb2 high mobility group box 2 0.101
Orc1 origin recognition complex, subunit 1 0.099
Rasa1 RAS p21 protein activator 1 0.098
Ccnb2 cyclin B2 0.098
Dusp9 dual specificity phosphatase 9 0.098
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.098
Cdc45 cell division cycle 45 homolog (S. cerevisiae) 0.097
Ccdc99 coiled-coil domain containing 99 0.093
Racgap1 Rac GTPase-activating protein 1 0.091
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.089
Dkk2 dickkopf homolog 2 (Xenopus laevis) 0.089
Rbbp6 retinoblastoma binding protein 6 0.089
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 0.088
Cenpa centromere protein A 0.087
Brca1 breast cancer 1 0.083
Pola1 polymerase (DNA directed), alpha 1 0.082
C330027C09Rik RIKEN cDNA C330027C09 gene 0.082
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.081
Cdca5 cell division cycle associated 5 0.081
Eri2 exoribonuclease 2 0.081
Kif2a kinesin family member 2A 0.080
Birc5 baculoviral IAP repeat-containing 5 0.079
Blm Bloom syndrome, RecQ helicase-like 0.078
Xpo1 exportin 1, CRM1 homolog (yeast) 0.078
Topbp1 topoisomerase (DNA) II binding protein 1 0.076
Exo1 exonuclease 1 0.074
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Rattus norvegicus
Name Description Probability Func Analog Organism