The network for 'positive regulation of cellular catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cellular catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MIG1 Mig1p 0.158
RHO1 Rho1p 0.156
STE11 Ste11p 0.153
SPA2 Spa2p 0.135
BEM4 Bem4p 0.123
GYL1 Gyl1p 0.120
HSV2 Hsv2p 0.119
DCP2 Dcp2p 0.115
CDC16 Cdc16p 0.112
YDJ1 Ydj1p 0.111
GRR1 Grr1p 0.105
KEM1 Kem1p 0.100
BCY1 Bcy1p 0.100
RAD23 Rad23p 0.099
VAC7 Vac7p 0.095
ROM2 Rom2p 0.093
SLT2 Slt2p 0.093
PUB1 Pub1p 0.091
CDC23 Cdc23p 0.083
HSL1 Hsl1p 0.083
NTO1 Nto1p 0.082
SWC4 Swc4p 0.081
STE20 Ste20p 0.081
SUI2 Sui2p 0.080
MOB1 Mob1p 0.078
SUI3 Sui3p 0.076
TOM1 Tom1p 0.075
MNN9 Mnn9p 0.074
YAK1 Yak1p 0.072
SEC3 Sec3p 0.070
HMO1 Hmo1p 0.068
BEM3 Bem3p 0.068
TUS1 Tus1p 0.067
YTA7 Yta7p 0.067
RPN14 Rpn14p 0.066
GCD6 Gcd6p 0.066
RAD14 Rad14p 0.065
MKK1 Mkk1p 0.065
CAK1 Cak1p 0.064
GLN3 Gln3p 0.064
ITC1 Itc1p 0.062
ATG3 Atg3p 0.062
RGA2 Rga2p 0.061
CDC12 Cdc12p 0.061
PIP2 Pip2p 0.061
MET4 Met4p 0.060
RTT106 Rtt106p 0.060
UBP14 Ubp14p 0.059
HHO1 Hho1p 0.059
MIG2 Mig2p 0.058
VPS27 Vps27p 0.058
TAO3 Tao3p 0.057
PCL2 Pcl2p 0.057
AVO1 Avo1p 0.057
CKS1 Cks1p 0.056
UBR1 Ubr1p 0.056
PTP2 Ptp2p 0.056
UFO1 Ufo1p 0.056
RPT3 Rpt3p 0.056
DST1 Dst1p 0.054
SSC1 Ssc1p 0.054
BRO1 Bro1p 0.054
MYO4 Myo4p 0.053
VID28 Vid28p 0.053
MOB2 Mob2p 0.052
ATG13 Atg13p 0.052
STI1 Sti1p 0.052
DHH1 Dhh1p 0.052
YML081W hypothetical protein 0.052
GDS1 Gds1p 0.051
VPS41 Vps41p 0.049
AFT1 Aft1p 0.049
YPT53 Ypt53p 0.048
CYC8 Cyc8p 0.048
VPS4 Vps4p 0.048
GCD7 Gcd7p 0.047
MIG3 Mig3p 0.047
YIP4 Yip4p 0.047
PKP2 Pkp2p 0.047
FIG4 Fig4p 0.046
YAP1 Yap1p 0.045
SET2 Set2p 0.045
HXT3 Hxt3p 0.044
VMA8 Vma8p 0.044
BNI4 Bni4p 0.044
YPT31 Ypt31p 0.044
PDE2 Pde2p 0.044
APC2 Apc2p 0.044
MDM10 Mdm10p 0.044
PXA1 Pxa1p 0.043
SSA4 Ssa4p 0.043
TPK3 Tpk3p 0.043
FAA2 Faa2p 0.043
KIC1 Kic1p 0.043
SEC16 Sec16p 0.043
YLR455W hypothetical protein 0.042
MMS21 Mms21p 0.042
LYS5 Lys5p 0.042
MON1 Mon1p 0.041
SAS5 Sas5p 0.041
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
mpk-1 Protein MPK-1 0.238
nhr-34 Protein NHR-34 0.235
CELE_F47G4.4 Protein F47G4.4 0.172
sem-5 Protein SEM-5 0.167
atg-2 Protein ATG-2 0.117
lin-36 Protein LIN-36 0.113
unc-51 Protein UNC-51 0.112
egl-18 Protein EGL-18 0.106
elt-6 Protein ELT-6 0.105
unc-62 Protein UNC-62 0.104
mei-1 Protein MEI-1 0.090
cas-1 Protein CAS-1 0.089
F36D4.5 Protein F36D4.5 0.088
trr-1 Protein TRR-1 0.082
mrck-1 Protein MRCK-1 0.071
scd-1 Protein SCD-1 0.066
cks-1 Protein CKS-1 0.065
atfs-1 Protein ATFS-1 0.065
tpxl-1 Protein TPXL-1 0.064
trcs-2 Protein TRCS-2 0.063
egl-46 Protein EGL-46 0.062
sax-3 Protein SAX-3 0.062
cpr-4 Protein CPR-4 0.058
rhgf-2 Protein RHGF-2 0.057
stau-1 Protein STAU-1 0.056
zoo-1 Protein ZOO-1 0.054
imb-2 Protein IMB-2 0.052
ptr-2 Protein PTR-2 0.052
goa-1 Protein GOA-1 0.051
mcm-7 Protein MCM-7 0.051
toe-4 Protein TOE-4 0.050
fntb-1 Protein FNTB-1 0.050
F21A10.2 Protein F21A10.2 0.049
let-607 Protein LET-607 0.048
imp-2 Protein IMP-2 0.047
jnk-1 Protein JNK-1 0.047
pat-12 Protein PAT-12 0.046
Y55F3AM.9 Protein Y55F3AM.9 0.046
C16A3.4 Protein C16A3.4 0.046
nhr-6 Protein NHR-6 0.045
Y71H2AM.20 Protein Y71H2AM.20 0.045
cyld-1 Protein CYLD-1 0.045
sams-4 Protein SAMS-4 0.045
sli-1 Protein SLI-1 0.045
zyg-9 Protein ZYG-9 0.044
lin-48 Protein LIN-48 0.044
dpl-1 Protein DPL-1 0.043
ajm-1 Protein AJM-1 0.043
mcm-2 Protein MCM-2 0.043
rpn-1 Protein RPN-1 0.043
ptp-1 Protein PTP-1 0.042
lag-1 Protein LAG-1 0.041
mat-3 Protein MAT-3 0.041
rgl-1 Protein RGL-1 0.041
CELE_Y41E3.11 Protein Y41E3.11 0.041
trap-2 Protein TRAP-2 0.040
pat-3 Protein PAT-3 0.040
hsr-9 Protein HSR-9 0.039
pkg-1 Protein PKG-1 0.039
tag-343 Protein TAG-343 0.039
rme-4 Protein RME-4 0.039
F52G3.1 Protein F52G3.1 0.038
R90.1 Protein R90.1 0.038
egl-8 Protein EGL-8 0.038
vav-1 Protein VAV-1 0.038
K08E3.5 Protein K08E3.5 0.037
rnr-1 Protein RNR-1 0.037
nhr-256 Protein NHR-256 0.037
magi-1 Protein MAGI-1 0.037
smp-1 Protein SMP-1 0.037
ttx-1 Protein TTX-1 0.036
let-60 Protein LET-60 0.036
cam-1 Protein CAM-1 0.036
rab-5 Protein RAB-5 0.036
cdc-48.2 Protein CDC-48.2 0.035
klp-16 Protein KLP-16 0.035
C11E4.6 Protein C11E4.6 0.035
itr-1 Protein ITR-1 0.034
ptp-3 Protein PTP-3 0.034
sma-9 Protein SMA-9 0.034
ubq-1 Protein UBQ-1 0.034
F31C3.2 Protein F31C3.2 0.034
ptp-4 Protein PTP-4 0.034
eef-2 Protein EEF-2 0.034
pme-3 Protein PME-3 0.033
lon-2 Protein LON-2 0.033
gei-8 Protein GEI-8 0.033
abl-1 Protein ABL-1 0.033
crt-1 Protein CRT-1 0.033
spp-8 Protein SPP-8 0.033
nhr-35 Protein NHR-35 0.033
T14B1.1 Protein T14B1.1 0.032
csn-1 Protein CSN-1 0.032
gar-3 Protein GAR-3 0.032
rpl-11.1 Protein RPL-11.1 0.032
Y54E5A.7 Protein Y54E5A.7 0.032
sea-2 Protein SEA-2 0.031
rgs-7 Protein RGS-7 0.031
F10B5.8 Protein F10B5.8 0.031
F13E6.4 Protein F13E6.4 0.031
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
foxa2 forkhead box A2 0.658
hspa4a heat shock protein 4a 0.407
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.399
cfl2l cofilin 2, like 0.348
cnn2 calponin 2 0.348
rtcd1 RNA terminal phosphate cyclase domain 1 0.348
adrb2a adrenergic receptor, beta 2a 0.344
tagln2 transgelin 2 0.328
baxa bcl2-associated X protein, a 0.310
bcl2 B-cell leukemia/lymphoma 2 0.309
jun jun proto-oncogene 0.302
ahctf1 AT hook containing transcription factor 1 0.295
mcl1b myeloid cell leukemia sequence 1b 0.290
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.288
unc5b unc-5 homolog B (C. elegans) 0.288
psen1 presenilin 1 0.286
bmper BMP binding endothelial regulator 0.282
si:dkey-233h2.3 si:dkey-233h2.3 0.271
rtn1a reticulon 1a 0.251
dtng dystrobrevin, gamma and dystrobrevin, gamma-like 0.249
ncor1 nuclear receptor co-repressor 1 0.246
mxi1 max interacting protein 0.243
ccnb1 cyclin B1 0.241
si:dkey-145p14.5 si:dkey-145p14.5 0.226
ctnnb1 catenin (cadherin-associated protein), beta 1 0.222
nf1a neurofibromin 1a 0.220
smad2 MAD homolog 2 (Drosophila) 0.212
ilk integrin linked kinase 0.201
pak2a p21 (CDKN1A)-activated kinase 2a 0.199
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.194
hnrnpk heterogeneous nuclear ribonucleoprotein K 0.193
eomesa eomesodermin homolog a 0.193
nanos3 nanos homolog 3 0.191
mapre1l microtubule-associated protein, RP/EB family, member 1, like 0.190
tp73 tumor protein p73 0.189
pdlim1 PDZ and LIM domain 1 (elfin) 0.185
bida BH3 interacting domain death agonist 0.182
limk2 LIM domain kinase 2 0.177
gata5 GATA-binding protein 5 0.176
zgc:55891 zgc:55891 0.176
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.175
midn midnolin 0.175
kctd15a potassium channel tetramerisation domain containing 15a 0.165
si:dkey-12o15.1 si:dkey-12o15.1 0.164
dag1 dystroglycan 1 0.162
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.159
tpm4 tropomyosin 4 0.158
cited3 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3 0.157
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.155
rasl11b RAS-like, family 11, member B 0.155
gro2 groucho 2 0.154
pole2 polymerase (DNA directed), epsilon 2 0.152
sf3b1 splicing factor 3b, subunit 1 0.152
csad cysteine sulfinic acid decarboxylase 0.150
birc5a baculoviral IAP repeat-containing 5a 0.149
foxo3b forkhead box O3b 0.149
s100b S100 calcium binding protein, beta (neural) 0.148
sirt1 sirtuin (silent mating type information regulation 2 homolog) 1 0.147
depdc1a DEP domain containing 1a 0.147
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.145
dusp6 dual specificity phosphatase 6 0.144
ccna2 cyclin A2 0.143
hmgb1a high-mobility group box 1a 0.142
klf4a Kruppel-like transcription factor 4a 0.141
bag6 BCL2-associated athanogene 6 0.141
yap1 Yes-associated protein 1 0.140
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.139
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.138
slc4a2a solute carrier family 4, anion exchanger, member 2a 0.138
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.136
ccnb2 cyclin B2 0.136
ccng1 cyclin G1 0.136
mcl1a myeloid cell leukemia sequence 1a 0.135
efnb2a ephrin B2a 0.134
si:dkey-7c22.2 si:dkey-7c22.2 0.134
cul1a cullin 1a 0.133
hsp90a.2 heat shock protein 90-alpha 2 0.132
csnk1da casein kinase 1, delta a 0.132
plxnb2a plexin b2a 0.131
gpib glucose phosphate isomerase b 0.130
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.130
c6 complement component 6 0.129
rhoab ras homolog gene family, member Ab 0.127
tpst1 tyrosylprotein sulfotransferase 1 0.127
cotl1 coactosin-like 1 (Dictyostelium) 0.127
plk1 polo-like kinase 1 (Drosophila) 0.126
zgc:153061 zgc:153061 0.125
acvr1b activin A receptor, type IB 0.125
hsp70l heat shock cognate 70-kd protein, like 0.124
suv39h1b suppressor of variegation 3-9 homolog 1b 0.124
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.123
si:dkeyp-84f11.5 si:dkeyp-84f11.5 0.123
adra2b adrenergic, alpha-2B-, receptor 0.122
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.122
chaf1b chromatin assembly factor 1, subunit B 0.122
LOC100151531 zinc finger protein Gfi-1b-like 0.121
slc25a22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.121
mecp2 methyl CpG binding protein 2 0.121
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.121
tomm34 translocase of outer mitochondrial membrane 34 0.120
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.926
msps mini spindles 0.710
puc puckered 0.699
Rheb CG1081 gene product from transcript CG1081-RA 0.535
Stat92E Signal-transducer and activator of transcription protein at 92E 0.506
Rac1 CG2248 gene product from transcript CG2248-RA 0.503
Atg18 Autophagy-specific gene 18 0.466
Dcr-2 Dicer-2 0.457
Pkn Protein kinase related to protein kinase N 0.453
dys dysfusion 0.406
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.376
Hnf4 Hepatocyte nuclear factor 4 0.341
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.337
Su(H) Suppressor of Hairless 0.321
dm diminutive 0.312
cenG1A centaurin gamma 1A 0.309
Dhc64C Dynein heavy chain 64C 0.288
Mer Merlin 0.281
cta concertina 0.280
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.263
Atg13 Autophagy-specific gene 13 0.257
Rho1 CG8416 gene product from transcript CG8416-RB 0.253
dos daughter of sevenless 0.245
N Notch 0.241
Ras85D Ras oncogene at 85D 0.241
Marf Mitochondrial assembly regulatory factor 0.238
Akt1 CG4006 gene product from transcript CG4006-RA 0.235
aub aubergine 0.235
rpr reaper 0.228
Lnk CG17367 gene product from transcript CG17367-RC 0.218
CG11486 CG11486 gene product from transcript CG11486-RG 0.215
car carnation 0.210
bsk basket 0.209
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.207
Top1 Topoisomerase 1 0.200
htl heartless 0.188
dik diskette 0.187
shi shibire 0.185
trio CG18214 gene product from transcript CG18214-RA 0.177
Su(dx) Suppressor of deltex 0.177
Sin3A CG8815 gene product from transcript CG8815-RC 0.177
CycA Cyclin A 0.172
sima similar 0.170
Ced-12 CG5336 gene product from transcript CG5336-RA 0.168
Trim9 CG31721 gene product from transcript CG31721-RB 0.162
chic chickadee 0.155
NaCP60E Na channel protein 60E 0.154
CG4771 CG4771 gene product from transcript CG4771-RA 0.152
stg string 0.151
yki yorkie 0.146
rl rolled 0.143
neur neuralized 0.142
mts microtubule star 0.141
Mtl Mig-2-like 0.139
mei-41 meiotic 41 0.137
Mekk1 CG7717 gene product from transcript CG7717-RB 0.136
cno canoe 0.134
shg shotgun 0.134
Top3alpha Topoisomerase 3alpha 0.132
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.131
eIF-4E Eukaryotic initiation factor 4E 0.130
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.130
gwl greatwall 0.129
Pten CG5671 gene product from transcript CG5671-RB 0.127
CG1021 CG1021 gene product from transcript CG1021-RE 0.126
rok Rho-kinase 0.125
Smg1 CG32743 gene product from transcript CG32743-RA 0.124
Hr96 Hormone receptor-like in 96 0.122
Toll-7 CG8595 gene product from transcript CG8595-RA 0.121
EcR Ecdysone receptor 0.120
Wnk CG7177 gene product from transcript CG7177-RA 0.119
Smox Smad on X 0.119
drk downstream of receptor kinase 0.119
feo fascetto 0.119
Gap69C GTPase-activating protein 69C 0.118
gek genghis khan 0.115
spin spinster 0.114
Pk61C Protein kinase 61C 0.113
HLH106 Helix loop helix protein 106 0.112
mus209 mutagen-sensitive 209 0.110
edl ETS-domain lacking 0.109
drpr draper 0.109
rin rasputin 0.108
cpa capping protein alpha 0.108
InR Insulin-like receptor 0.107
Orc2 Origin recognition complex subunit 2 0.106
px plexus 0.105
jar jaguar 0.104
S6k RPS6-p70-protein kinase 0.103
msn misshapen 0.102
rhi rhino 0.100
l(2)k16918 lethal (2) k16918 0.100
Sir2 CG5216 gene product from transcript CG5216-RA 0.100
Git CG16728 gene product from transcript CG16728-RA 0.100
tmod tropomodulin 0.099
Klc Kinesin light chain 0.098
shark Src homology 2, ankyrin repeat, tyrosine kinase 0.098
G-ialpha65A G protein alphai subunit 65A 0.098
dup double parked 0.097
Dap160 Dynamin associated protein 160 0.096
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.998
SQSTM1 sequestosome 1 0.997
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.996
DNM2 dynamin 2 0.989
HTT huntingtin 0.982
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.979
RB1 retinoblastoma 1 0.960
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.960
BCL2 B-cell CLL/lymphoma 2 0.956
SMAD3 SMAD family member 3 0.956
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.954
UBC ubiquitin C 0.954
IGF1R insulin-like growth factor 1 receptor 0.951
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.933
NCF2 neutrophil cytosolic factor 2 0.929
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.929
EGFR epidermal growth factor receptor 0.928
BCL2L1 BCL2-like 1 0.924
SMAD2 SMAD family member 2 0.917
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.898
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.874
ARRB1 arrestin, beta 1 0.870
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.869
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.867
JUN jun proto-oncogene 0.867
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.851
SMAD4 SMAD family member 4 0.846
TOB1 transducer of ERBB2, 1 0.834
BCAR1 breast cancer anti-estrogen resistance 1 0.829
FGFR2 fibroblast growth factor receptor 2 0.824
TNRC6A trinucleotide repeat containing 6A 0.816
SMAD7 SMAD family member 7 0.804
SFN stratifin 0.794
RHOA ras homolog gene family, member A 0.792
S100A11 S100 calcium binding protein A11 0.789
S100A6 S100 calcium binding protein A6 0.786
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.780
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.774
EXOSC3 exosome component 3 0.768
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.759
BBS10 Bardet-Biedl syndrome 10 0.752
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.739
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.733
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.731
SH3RF1 SH3 domain containing ring finger 1 0.711
EXOSC10 exosome component 10 0.680
PTK2 PTK2 protein tyrosine kinase 2 0.679
SNX9 sorting nexin 9 0.679
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.673
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.657
FGFR1 fibroblast growth factor receptor 1 0.654
RIN3 Ras and Rab interactor 3 0.651
MAP2K4 mitogen-activated protein kinase kinase 4 0.651
SMAD1 SMAD family member 1 0.650
DUSP1 dual specificity phosphatase 1 0.631
FASLG Fas ligand (TNF superfamily, member 6) 0.626
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.625
S100A4 S100 calcium binding protein A4 0.611
SH3KBP1 SH3-domain kinase binding protein 1 0.601
FOS FBJ murine osteosarcoma viral oncogene homolog 0.596
CSNK1E casein kinase 1, epsilon 0.578
GRB10 growth factor receptor-bound protein 10 0.577
ADRBK1 adrenergic, beta, receptor kinase 1 0.576
EXOSC7 exosome component 7 0.574
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.565
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.563
BAD BCL2-associated agonist of cell death 0.558
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.558
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.553
SKIL SKI-like oncogene 0.548
CSNK1D casein kinase 1, delta 0.543
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.543
PSEN1 presenilin 1 0.539
SMAD5 SMAD family member 5 0.535
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.534
S100A8 S100 calcium binding protein A8 0.532
SYNJ1 synaptojanin 1 0.530
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.528
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.527
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.516
IRS2 insulin receptor substrate 2 0.509
MAPT microtubule-associated protein tau 0.509
GABARAPL1 GABA(A) receptor-associated protein like 1 0.507
FKBP4 FK506 binding protein 4, 59kDa 0.505
LRRK2 leucine-rich repeat kinase 2 0.502
NCK2 NCK adaptor protein 2 0.501
HIPK2 homeodomain interacting protein kinase 2 0.501
PLK1 polo-like kinase 1 0.493
NCL nucleolin 0.491
MARK3 MAP/microtubule affinity-regulating kinase 3 0.488
S100B S100 calcium binding protein B 0.486
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.483
DNM1 dynamin 1 0.483
PKN3 protein kinase N3 0.482
ZFYVE9 zinc finger, FYVE domain containing 9 0.464
TP53 tumor protein p53 0.453
EPS15 epidermal growth factor receptor pathway substrate 15 0.452
NCKAP1 NCK-associated protein 1 0.444
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.426
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 0.989
Pnpla2 patatin-like phospholipase domain containing 2 0.988
Grb2 growth factor receptor bound protein 2 0.959
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.939
Pparg peroxisome proliferator activated receptor gamma 0.913
Efnb2 ephrin B2 0.874
Gsk3b glycogen synthase kinase 3 beta 0.848
Rac1 RAS-related C3 botulinum substrate 1 0.841
Plxna1 plexin A1 0.828
Braf Braf transforming gene 0.827
Git1 G protein-coupled receptor kinase-interactor 1 0.813
Pten phosphatase and tensin homolog 0.811
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.800
Axin1 axin 1 0.800
Foxo1 forkhead box O1 0.787
Mdm2 transformed mouse 3T3 cell double minute 2 0.785
Hmha1 histocompatibility (minor) HA-1 0.784
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.774
Ccna2 cyclin A2 0.762
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.747
Dlg4 discs, large homolog 4 (Drosophila) 0.745
Kl klotho 0.741
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.730
Cyld cylindromatosis (turban tumor syndrome) 0.718
Trp73 transformation related protein 73 0.718
Arrb2 arrestin, beta 2 0.705
Trp53 transformation related protein 53 0.700
Mki67 antigen identified by monoclonal antibody Ki 67 0.676
Ccnb2 cyclin B2 0.654
Hdac7 histone deacetylase 7 0.652
Usp9x ubiquitin specific peptidase 9, X chromosome 0.649
Vav1 vav 1 oncogene 0.641
Per2 period homolog 2 (Drosophila) 0.633
Rasgrp2 RAS, guanyl releasing protein 2 0.631
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.618
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.604
Plxnb1 plexin B1 0.599
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.598
Nf1 neurofibromatosis 1 0.586
Gata5 GATA binding protein 5 0.577
Tspan9 tetraspanin 9 0.569
Pim1 proviral integration site 1 0.568
Lep leptin 0.565
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.564
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.561
Ccnb1 cyclin B1 0.555
Ranbp9 RAN binding protein 9 0.553
Tsc1 tuberous sclerosis 1 0.534
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.532
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.520
Atf2 activating transcription factor 2 0.518
Adrb1 adrenergic receptor, beta 1 0.514
Socs1 suppressor of cytokine signaling 1 0.513
Selplg selectin, platelet (p-selectin) ligand 0.509
App amyloid beta (A4) precursor protein 0.508
Insr insulin receptor 0.505
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.504
Laptm5 lysosomal-associated protein transmembrane 5 0.500
Dctn1 dynactin 1 0.497
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.476
Nrp1 neuropilin 1 0.476
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.475
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.472
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.470
Irs2 insulin receptor substrate 2 0.464
Akt1 thymoma viral proto-oncogene 1 0.463
Cic capicua homolog (Drosophila) 0.457
Tbx3 T-box 3 0.451
Adam11 a disintegrin and metallopeptidase domain 11 0.436
Klf3 Kruppel-like factor 3 (basic) 0.427
Cdk1 cyclin-dependent kinase 1 0.426
Atxn7l3 ataxin 7-like 3 0.426
Efna1 ephrin A1 0.422
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.421
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.417
Lyst lysosomal trafficking regulator 0.411
Prkcd protein kinase C, delta 0.411
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.401
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.400
Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 0.396
Jag2 jagged 2 0.396
Bglap bone gamma carboxyglutamate protein 0.395
Rhob ras homolog gene family, member B 0.391
Epha4 Eph receptor A4 0.390
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.384
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.379
Irf5 interferon regulatory factor 5 0.375
Pdpk1 3-phosphoinositide dependent protein kinase 1 0.374
Atf4 activating transcription factor 4 0.373
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 0.368
Cd37 CD37 antigen 0.367
Trim32 tripartite motif-containing 32 0.367
Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 0.367
Mapk14 mitogen-activated protein kinase 14 0.365
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.361
Lepr leptin receptor 0.358
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.357
Scn5a sodium channel, voltage-gated, type V, alpha 0.354
Ccne1 cyclin E1 0.354
Epha1 Eph receptor A1 0.353
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.249
Fos FBJ osteosarcoma oncogene 0.166
Jun Jun oncogene 0.155
Btg2 BTG family, member 2 0.147
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.129
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.128
Atf3 activating transcription factor 3 0.121
Homer1 homer homolog 1 (Drosophila) 0.118
Myl9 myosin, light chain 9, regulatory 0.114
Pja2 praja 2, RING-H2 motif containing 0.107
Pctk2 PCTAIRE protein kinase 2 0.103
Egr1 early growth response 1 0.097
Prkcb protein kinase C, beta 0.086
Anxa2 annexin A2 0.085
Zfp36 zinc finger protein 36 0.084
Dusp1 dual specificity phosphatase 1 0.081
Top2a topoisomerase (DNA) II alpha 0.078
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.076
Egr2 early growth response 2 0.074
Stip1 stress-induced phosphoprotein 1 0.074
Syt4 synaptotagmin IV 0.073
Epas1 endothelial PAS domain protein 1 0.065
Amph amphiphysin 0.064
Cpt2 carnitine palmitoyltransferase 2 0.063
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.063
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.062
Rplp0 ribosomal protein, large, P0 0.061
Arpc2 actin related protein 2/3 complex, subunit 2 0.056
Arl1 ADP-ribosylation factor-like 1 0.056
Anapc5 anaphase-promoting complex subunit 5 0.056
Gria2 glutamate receptor, ionotropic, AMPA 2 0.054
Kifc1 kinesin family member C1 0.053
Zfp260 zinc finger protein 260 0.052
Myo1c myosin IC 0.051
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.051
Hk1 hexokinase 1 0.051
Usf2 upstream transcription factor 2, c-fos interacting 0.049
Klf6 Kruppel-like factor 6 0.049
Olr416 olfactory receptor 416 0.048
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.048
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.048
Ccl22 chemokine (C-C motif) ligand 22 0.047
Traf4af1 TRAF4 associated factor 1 0.047
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.047
Eef2 eukaryotic translation elongation factor 2 0.047
Racgap1 Rac GTPase-activating protein 1 0.047
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.047
Dpp6 dipeptidylpeptidase 6 0.046
Dusp5 dual specificity phosphatase 5 0.046
Rph3a rabphilin 3A 0.045
Shank2 SH3 and multiple ankyrin repeat domains 2 0.044
Mtus1 mitochondrial tumor suppressor 1 0.043
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.043
Ccne1 cyclin E1 0.043
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.042
Vegfb vascular endothelial growth factor B 0.042
Lhx5 LIM homeobox 5 0.041
Tars threonyl-tRNA synthetase 0.041
Espn espin 0.041
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.041
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.040
Phc1 polyhomeotic homolog 1 (Drosophila) 0.040
Errfi1 ERBB receptor feedback inhibitor 1 0.040
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.040
Ube2c ubiquitin-conjugating enzyme E2C 0.040
Ier2 immediate early response 2 0.040
Cfp complement factor properdin 0.040
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.039
Tas2r119 taste receptor, type 2, member 119 0.039
Hand2 heart and neural crest derivatives expressed 2 0.039
Usp19 ubiquitin specific peptidase 19 0.039
Robo2 roundabout homolog 2 (Drosophila) 0.039
Chrm1 cholinergic receptor, muscarinic 1 0.038
Lphn2 latrophilin 2 0.038
Prrx1 paired related homeobox 1 0.037
Egr3 early growth response 3 0.036
Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.036
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.036
Dusp6 dual specificity phosphatase 6 0.036
Ccl3 chemokine (C-C motif) ligand 3 0.036
Phf1 PHD finger protein 1 0.036
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.035
Epn1 Epsin 1 0.035
Rac1 ras-related C3 botulinum toxin substrate 1 0.035
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.035
Grifin galectin-related inter-fiber protein 0.034
Pum1 pumilio homolog 1 (Drosophila) 0.034
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.034
Vcsa1 variable coding sequence A1 0.034
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.034
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.033
Mdm2 Mdm2 p53 binding protein homolog (mouse) 0.033
Cap2 CAP, adenylate cyclase-associated protein, 2 (yeast) 0.033
Epha2 Eph receptor A2 0.033
Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.033
Hpca hippocalcin 0.033
Actb actin, beta 0.033
Camk4 calcium/calmodulin-dependent protein kinase IV 0.033
Akap1 A kinase (PRKA) anchor protein 1 0.032
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.032