The network for 'mitochondrial translation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitochondrial translation

The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
IFM1 Ifm1p 0.981
MSF1 Msf1p 0.950
RPO41 Rpo41p 0.932
SLM5 Slm5p 0.842
MEF1 Mef1p 0.794
NAM2 Nam2p 0.766
PET111 Pet111p 0.731
MSE1 Mse1p 0.662
MST1 Mst1p 0.622
CCM1 Ccm1p 0.608
SES1 Ses1p 0.483
CYM1 Cym1p 0.453
MDM38 Mdm38p 0.404
MSY1 Msy1p 0.365
UPS2 Ups2p 0.330
RSM23 Rsm23p 0.325
MRP20 Mrp20p 0.323
MRF1 Mrf1p 0.281
MSR1 Msr1p 0.271
MTF2 Mtf2p 0.270
TUF1 Tuf1p 0.257
PIR1 Pir1p 0.236
MSD1 Msd1p 0.231
MGM1 Mgm1p 0.225
AIM32 Aim32p 0.220
ATP25 Atp25p 0.212
DSS1 Dss1p 0.206
AIM10 Aim10p 0.201
COQ1 Coq1p 0.190
RRF1 Rrf1p 0.190
FCJ1 Fcj1p 0.185
SSC1 Ssc1p 0.183
DIA4 Dia4p 0.176
EHD3 Ehd3p 0.171
AEP3 Aep3p 0.166
HER2 Her2p 0.166
OCT1 Oct1p 0.163
ISM1 Ism1p 0.162
PET54 Pet54p 0.162
TCM62 Tcm62p 0.162
MRP10 Mrp10p 0.156
RSM24 Rsm24p 0.151
AEP1 Aep1p 0.146
PET112 Pet112p 0.141
AGC1 Agc1p 0.137
CAB4 Cab4p 0.133
ACN9 Acn9p 0.128
ISA2 Isa2p 0.121
MDM32 Mdm32p 0.120
FYV4 Fyv4p 0.119
MRP4 Mrp4p 0.117
CBP3 Cbp3p 0.116
MRPL28 Mrpl28p 0.116
MSS2 Mss2p 0.114
PAR32 Par32p 0.110
GYL1 Gyl1p 0.110
MSK1 Msk1p 0.095
MRPL1 Mrpl1p 0.094
BI4 Bi4p 0.093
MTF1 Mtf1p 0.093
COX10 Cox10p 0.091
NDE1 Nde1p 0.091
RRG8 Rrg8p 0.090
SAL1 Sal1p 0.087
AIM24 Aim24p 0.086
MRPL35 Mrpl35p 0.083
SSQ1 Ssq1p 0.083
PET494 Pet494p 0.079
VAS1 Vas1p 0.079
ART10 Art10p 0.078
FZO1 Fzo1p 0.077
SWS2 Sws2p 0.077
YML6 Yml6p 0.076
YGR102C hypothetical protein 0.076
RRG9 Rrg9p 0.076
PET127 Pet127p 0.076
QRI5 Qri5p 0.076
GUF1 Guf1p 0.074
MDH1 Mdh1p 0.074
URA4 Ura4p 0.074
MRPL25 Mrpl25p 0.074
OMS1 Oms1p 0.073
FMP30 Fmp30p 0.073
TYS1 Tys1p 0.072
AIM45 Aim45p 0.072
POA1 Poa1p 0.071
PNT1 Pnt1p 0.071
PIM1 Pim1p 0.070
YRB1 Yrb1p 0.070
CIR2 Cir2p 0.069
AIM33 Aim33p 0.069
MSS18 Mss18p 0.068
ATP10 Atp10p 0.067
MRPL36 Mrpl36p 0.066
CTR1 Ctr1p 0.066
SLS1 Sls1p 0.065
YDR248C hypothetical protein 0.065
NGL1 Ngl1p 0.065
MSC6 Msc6p 0.064
YLR264C-A hypothetical protein 0.064
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ICT1 immature colon carcinoma transcript 1 0.991
IARS isoleucyl-tRNA synthetase 0.604
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.221
MRPS27 mitochondrial ribosomal protein S27 0.196
CARS cysteinyl-tRNA synthetase 0.170
MRPL32 mitochondrial ribosomal protein L32 0.146
MRPL1 mitochondrial ribosomal protein L1 0.114
MRPS9 mitochondrial ribosomal protein S9 0.111
MRPL46 mitochondrial ribosomal protein L46 0.085
MRPL19 mitochondrial ribosomal protein L19 0.077
MRPS15 mitochondrial ribosomal protein S15 0.066
TRIM63 tripartite motif containing 63 0.060
TRIM55 tripartite motif containing 55 0.060
MRRF mitochondrial ribosome recycling factor 0.057
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.056
RTN4IP1 reticulon 4 interacting protein 1 0.052
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.049
MRPL50 mitochondrial ribosomal protein L50 0.047
MRPS26 mitochondrial ribosomal protein S26 0.045
MRPL30 mitochondrial ribosomal protein L30 0.045
PPID peptidylprolyl isomerase D 0.040
LRPPRC leucine-rich PPR-motif containing 0.037
RNMTL1 RNA methyltransferase like 1 0.034
MRPL43 mitochondrial ribosomal protein L43 0.034
FASTKD2 FAST kinase domains 2 0.033
LIAS lipoic acid synthetase 0.033
GEMIN5 gem (nuclear organelle) associated protein 5 0.032
METTL17 methyltransferase like 17 0.030
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.030
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 0.028
METTL2A methyltransferase like 2A 0.028
TSFM Ts translation elongation factor, mitochondrial 0.025
MRPS23 mitochondrial ribosomal protein S23 0.025
SSBP1 single-stranded DNA binding protein 1 0.025
PFAS phosphoribosylformylglycinamidine synthase 0.024
MRPL39 mitochondrial ribosomal protein L39 0.024
C17orf80 chromosome 17 open reading frame 80 0.024
MRPL24 mitochondrial ribosomal protein L24 0.023
ZNF235 zinc finger protein 235 0.023
MRPL44 mitochondrial ribosomal protein L44 0.023
MRPL55 mitochondrial ribosomal protein L55 0.022
SCO1 SCO cytochrome oxidase deficient homolog 1 (yeast) 0.021
MARS methionyl-tRNA synthetase 0.021
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 0.020
C12orf62 chromosome 12 open reading frame 62 0.020
DAP3 death associated protein 3 0.019
MRPL45 mitochondrial ribosomal protein L45 0.018
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.018
KRT8 keratin 8 0.017
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.016
MRPS30 mitochondrial ribosomal protein S30 0.016
FBXO22 F-box protein 22 0.016
MRPL47 mitochondrial ribosomal protein L47 0.016
MRPS5 mitochondrial ribosomal protein S5 0.016
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.016
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.016
NFS1 NFS1 nitrogen fixation 1 homolog (S. cerevisiae) 0.015
MRPL41 mitochondrial ribosomal protein L41 0.015
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.015
COX1 cytochrome c oxidase subunit I 0.015
SURF1 surfeit 1 0.015
SLC7A5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 0.014
MRPL21 mitochondrial ribosomal protein L21 0.014
GEMIN4 gem (nuclear organelle) associated protein 4 0.014
MIPEP mitochondrial intermediate peptidase 0.014
RPUSD3 RNA pseudouridylate synthase domain containing 3 0.014
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.013
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.013
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.013
AARS alanyl-tRNA synthetase 0.013
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.013
YARS tyrosyl-tRNA synthetase 0.013
GUF1 GUF1 GTPase homolog (S. cerevisiae) 0.013
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.013
PYCR2 pyrroline-5-carboxylate reductase family, member 2 0.013
SFXN4 sideroflexin 4 0.013
C18orf55 chromosome 18 open reading frame 55 0.012
KIAA0391 KIAA0391 0.012
MRPS17 mitochondrial ribosomal protein S17 0.012
TRMT61B tRNA methyltransferase 61 homolog B (S. cerevisiae) 0.012
NUTF2 nuclear transport factor 2 0.011
PCCB propionyl CoA carboxylase, beta polypeptide 0.011
HOXB7 homeobox B7 0.011
MRPL10 mitochondrial ribosomal protein L10 0.011
USP22 ubiquitin specific peptidase 22 0.011
MRPS21 mitochondrial ribosomal protein S21 0.011
TRUB2 TruB pseudouridine (psi) synthase homolog 2 (E. coli) 0.011
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 0.011
TTC1 tetratricopeptide repeat domain 1 0.011
IDE insulin-degrading enzyme 0.010
MARS2 methionyl-tRNA synthetase 2, mitochondrial 0.010
TFB1M transcription factor B1, mitochondrial 0.010
TSEN2 tRNA splicing endonuclease 2 homolog (S. cerevisiae) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Mrpl3 mitochondrial ribosomal protein L3 0.633
Ndufaf4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 0.619
Coq5 coenzyme Q5 homolog, methyltransferase (yeast) 0.464
Hspa9 heat shock protein 9 0.366
Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 0.350
Timm8a1 translocase of inner mitochondrial membrane 8 homolog a1 (yeast) 0.290
Mmachc methylmalonic aciduria cblC type, with homocystinuria 0.272
Gfm1 G elongation factor, mitochondrial 1 0.269
Lrpprc leucine-rich PPR-motif containing 0.240
Immt inner membrane protein, mitochondrial 0.234
Hspd1 heat shock protein 1 (chaperonin) 0.213
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.194
Atad3a ATPase family, AAA domain containing 3A 0.180
Idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.176
Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.171
Fastkd2 FAST kinase domains 2 0.146
Qrsl1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.131
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.124
Timm10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.111
Mrps2 mitochondrial ribosomal protein S2 0.106
Opa1 optic atrophy 1 homolog (human) 0.100
Ndufaf1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 0.093
Tfam transcription factor A, mitochondrial 0.090
Fastkd5 FAST kinase domains 5 0.077
Yars2 tyrosyl-tRNA synthetase 2 (mitochondrial) 0.071
Mtif2 mitochondrial translational initiation factor 2 0.065
1300001I01Rik RIKEN cDNA 1300001I01 gene 0.059
Mrps26 mitochondrial ribosomal protein S26 0.058
Ecsit ECSIT homolog (Drosophila) 0.057
Afg3l2 AFG3(ATPase family gene 3)-like 2 (yeast) 0.055
Acad9 acyl-Coenzyme A dehydrogenase family, member 9 0.054
2610024G14Rik RIKEN cDNA 2610024G14 gene 0.049
Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.046
Mrpl45 mitochondrial ribosomal protein L45 0.044
Rpp14 ribonuclease P 14 subunit (human) 0.041
Uqcc ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast) 0.040
Ptcd3 pentatricopeptide repeat domain 3 0.038
Elac2 elaC homolog 2 (E. coli) 0.037
Rnmtl1 RNA methyltransferase like 1 0.037
2310030N02Rik RIKEN cDNA 2310030N02 gene 0.036
Ppif peptidylprolyl isomerase F (cyclophilin F) 0.035
Fam98a family with sequence similarity 98, member A 0.034
Timm9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.034
Nme1 non-metastatic cells 1, protein (NM23A) expressed in 0.032
Samm50 sorting and assembly machinery component 50 homolog (S. cerevisiae) 0.031
Mrpl16 mitochondrial ribosomal protein L16 0.028
Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.028
Kars lysyl-tRNA synthetase 0.027
Rtn4ip1 reticulon 4 interacting protein 1 0.026
Dnajc11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.025
Mrps22 mitochondrial ribosomal protein S22 0.024
Mrpl15 mitochondrial ribosomal protein L15 0.023
Tmem186 transmembrane protein 186 0.023
Usp10 ubiquitin specific peptidase 10 0.023
Lap3 leucine aminopeptidase 3 0.023
Iars isoleucine-tRNA synthetase 0.022
Fastkd1 FAST kinase domains 1 0.022
Rwdd4a RWD domain containing 4A 0.022
Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide 0.022
Iars2 isoleucine-tRNA synthetase 2, mitochondrial 0.022
L2hgdh L-2-hydroxyglutarate dehydrogenase 0.021
Mrpl46 mitochondrial ribosomal protein L46 0.021
Tbrg4 transforming growth factor beta regulated gene 4 0.020
Ppa1 pyrophosphatase (inorganic) 1 0.020
Ptcd2 pentatricopeptide repeat domain 2 0.020
Gcsh glycine cleavage system protein H (aminomethyl carrier) 0.020
Pgam5 phosphoglycerate mutase family member 5 0.019
9430016H08Rik RIKEN cDNA 9430016H08 gene 0.019
Akap1 A kinase (PRKA) anchor protein 1 0.019
Pdf peptide deformylase (mitochondrial) 0.019
Pdhx pyruvate dehydrogenase complex, component X 0.018
4933403F05Rik RIKEN cDNA 4933403F05 gene 0.018
Cul2 cullin 2 0.018
Polrmt polymerase (RNA) mitochondrial (DNA directed) 0.017
Foxo1 forkhead box O1 0.017
Cox15 COX15 homolog, cytochrome c oxidase assembly protein (yeast) 0.017
Eif2b3 eukaryotic translation initiation factor 2B, subunit 3 0.017
Fam82a2 family with sequence similarity 82, member A2 0.016
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.016
Coq7 demethyl-Q 7 0.016
Mrps30 mitochondrial ribosomal protein S30 0.015
Stard7 START domain containing 7 0.015
Armc1 armadillo repeat containing 1 0.015
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.015
Foxred1 FAD-dependent oxidoreductase domain containing 1 0.015
Mecr mitochondrial trans-2-enoyl-CoA reductase 0.015
C1qbp complement component 1, q subcomponent binding protein 0.014
1110002N22Rik RIKEN cDNA 1110002N22 gene 0.014
Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.014
Mettl17 methyltransferase like 17 0.014
Utp20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.014
Dhodh dihydroorotate dehydrogenase 0.014
Gars glycyl-tRNA synthetase 0.014
Hspa4 heat shock protein 4 0.013
Dus1l dihydrouridine synthase 1-like (S. cerevisiae) 0.013
1810026J23Rik RIKEN cDNA 1810026J23 gene 0.013
Phb2 prohibitin 2 0.013
Gnpat glyceronephosphate O-acyltransferase 0.013
Mrpl39 mitochondrial ribosomal protein L39 0.013
Tomm70a translocase of outer mitochondrial membrane 70 homolog A (yeast) 0.013
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Rattus norvegicus
Name Description Probability Func Analog Organism