The network for 'positive regulation of sodium ion transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of sodium ion transport

Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLN3 Gln3p 0.376
FPK1 Fpk1p 0.265
MIG1 Mig1p 0.226
CSR2 Csr2p 0.191
HAL5 Hal5p 0.190
TRA1 Tra1p 0.164
MIG3 Mig3p 0.147
MIG2 Mig2p 0.146
YAK1 Yak1p 0.140
HXT3 Hxt3p 0.137
YKR075C hypothetical protein 0.134
GAT2 Gat2p 0.130
CBK1 Cbk1p 0.120
CRZ1 Crz1p 0.107
YPL014W hypothetical protein 0.102
SSK2 Ssk2p 0.100
HAL1 Hal1p 0.095
FMP48 Fmp48p 0.086
NRG1 Nrg1p 0.084
HSF1 Hsf1p 0.077
CMK2 Cmk2p 0.076
YPK2 Ypk2p 0.074
DAL81 Dal81p 0.073
ATG29 Atg29p 0.073
HSP42 Hsp42p 0.069
SAC7 Sac7p 0.066
HRK1 Hrk1p 0.065
ZAP1 Zap1p 0.062
TOR2 Tor2p 0.061
NUP157 Nup157p 0.061
YPT53 Ypt53p 0.058
PST1 Pst1p 0.057
RGS2 Rgs2p 0.056
MOB1 Mob1p 0.055
MDS3 Mds3p 0.055
MSN2 Msn2p 0.052
YBR235W hypothetical protein 0.052
MOT3 Mot3p 0.050
HST3 Hst3p 0.049
DCS2 Dcs2p 0.049
POG1 Pog1p 0.047
YKL187C hypothetical protein 0.045
TOS3 Tos3p 0.044
IRC23 Irc23p 0.042
YNR014W hypothetical protein 0.041
NDD1 Ndd1p 0.040
SNF3 Snf3p 0.040
SRD1 Srd1p 0.040
YIR035C hypothetical protein 0.039
HXT1 Hxt1p 0.039
CDC4 Cdc4p 0.038
LEU2 Leu2p 0.037
PHM8 Phm8p 0.037
FAR3 Far3p 0.037
PRR2 Prr2p 0.037
STP4 Stp4p 0.037
GIS4 Gis4p 0.037
UBP9 Ubp9p 0.037
VHS1 Vhs1p 0.037
SWI1 Swi1p 0.036
PMD1 Pmd1p 0.036
NTO1 Nto1p 0.036
YLR162W hypothetical protein 0.036
RMA1 Rma1p 0.036
AGP2 Agp2p 0.035
BSC2 Bsc2p 0.035
TYE7 Tye7p 0.035
IXR1 Ixr1p 0.035
YNL234W hypothetical protein 0.035
ICS2 Ics2p 0.035
YLR264C-A hypothetical protein 0.035
TSC11 Tsc11p 0.035
SKS1 Sks1p 0.034
SBE22 Sbe22p 0.034
CHS1 Chs1p 0.034
YOL038C-A hypothetical protein 0.034
YPR157W hypothetical protein 0.033
PHO12 Pho12p 0.033
GIS3 Gis3p 0.033
ARP10 Arp10p 0.033
YNL144C hypothetical protein 0.033
RPI1 Rpi1p 0.033
YJL107C hypothetical protein 0.033
YER130C hypothetical protein 0.032
HOR2 Hor2p 0.032
ATF1 Atf1p 0.032
TPO2 Tpo2p 0.032
TIP1 Tip1p 0.032
EAR1 Ear1p 0.032
WSC4 Wsc4p 0.032
IRC8 Irc8p 0.032
HXT11 Hxt11p 0.032
MET4 Met4p 0.032
YAR068W hypothetical protein 0.031
SSU1 Ssu1p 0.030
AZF1 Azf1p 0.030
AFT1 Aft1p 0.030
ROG3 Rog3p 0.030
SWC4 Swc4p 0.030
YLR297W hypothetical protein 0.030
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TBX5 T-box 5 0.401
CXCL3 chemokine (C-X-C motif) ligand 3 0.393
CXCL2 chemokine (C-X-C motif) ligand 2 0.385
IL8 interleukin 8 0.330
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.200
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.161
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.117
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.108
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.094
SNTG2 syntrophin, gamma 2 0.087
MARK3 MAP/microtubule affinity-regulating kinase 3 0.084
KLHL3 kelch-like 3 (Drosophila) 0.084
VAC14 Vac14 homolog (S. cerevisiae) 0.066
DTNA dystrobrevin, alpha 0.064
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.059
SFN stratifin 0.053
WNK1 WNK lysine deficient protein kinase 1 0.044
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.039
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.037
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.033
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.030
ADORA2A adenosine A2a receptor 0.029
SCNN1B sodium channel, nonvoltage-gated 1, beta 0.028
DCTN1 dynactin 1 0.028
CCL20 chemokine (C-C motif) ligand 20 0.026
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.026
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.026
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.023
SYNM synemin, intermediate filament protein 0.021
MAPT microtubule-associated protein tau 0.021
IL6 interleukin 6 (interferon, beta 2) 0.020
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.019
HMG20A high mobility group 20A 0.018
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.017
SQSTM1 sequestosome 1 0.016
TSC22D4 TSC22 domain family, member 4 0.016
DTNB dystrobrevin, beta 0.016
MMP23B matrix metallopeptidase 23B 0.016
ARRDC3 arrestin domain containing 3 0.016
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.016
PDPK1 3-phosphoinositide dependent protein kinase-1 0.015
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.014
DSP desmoplakin 0.013
CHUK conserved helix-loop-helix ubiquitous kinase 0.013
OXSR1 oxidative-stress responsive 1 0.013
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.012
SH3RF1 SH3 domain containing ring finger 1 0.012
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.011
DSC2 desmocollin 2 0.011
KRT8 keratin 8 0.011
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.011
SLC9A1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.010
IL1B interleukin 1, beta 0.010
DGCR14 DiGeorge syndrome critical region gene 14 0.010
CCL14 chemokine (C-C motif) ligand 14 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.869
Cckbr cholecystokinin B receptor 0.586
Ikbkb inhibitor of kappaB kinase beta 0.548
Gata4 GATA binding protein 4 0.372
Ldb3 LIM domain binding 3 0.307
Lep leptin 0.266
Chuk conserved helix-loop-helix ubiquitous kinase 0.261
Ikbkg inhibitor of kappaB kinase gamma 0.240
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.217
Atoh7 atonal homolog 7 (Drosophila) 0.188
Cyld cylindromatosis (turban tumor syndrome) 0.183
Gh growth hormone 0.180
Syt8 synaptotagmin VIII 0.177
Pparg peroxisome proliferator activated receptor gamma 0.155
Rnf112 ring finger protein 112 0.145
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.139
Rac1 RAS-related C3 botulinum substrate 1 0.137
Mesp1 mesoderm posterior 1 0.137
Omp olfactory marker protein 0.126
Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 0.120
Rnf11 ring finger protein 11 0.113
Lmx1b LIM homeobox transcription factor 1 beta 0.107
Adrb3 adrenergic receptor, beta 3 0.105
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.104
Foxe1 forkhead box E1 0.104
Dmd dystrophin, muscular dystrophy 0.102
Grb10 growth factor receptor bound protein 10 0.099
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.097
Chl1 cell adhesion molecule with homology to L1CAM 0.094
Nkx3-2 NK3 homeobox 2 0.093
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.091
Fgf3 fibroblast growth factor 3 0.090
Prnp prion protein 0.089
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.083
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.082
Plp1 proteolipid protein (myelin) 1 0.079
Kcnk7 potassium channel, subfamily K, member 7 0.073
Cd40 CD40 antigen 0.073
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.072
Zfpm2 zinc finger protein, multitype 2 0.072
Ache acetylcholinesterase 0.070
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.069
Tbx5 T-box 5 0.069
ND6 NADH dehydrogenase subunit 6 0.069
Actn2 actinin alpha 2 0.069
Vegfa vascular endothelial growth factor A 0.068
Npy1r neuropeptide Y receptor Y1 0.068
Ryr2 ryanodine receptor 2, cardiac 0.067
1700065I17Rik RIKEN cDNA 1700065I17 gene 0.066
Fut2 fucosyltransferase 2 0.065
Vsnl1 visinin-like 1 0.064
Sry sex determining region of Chr Y 0.060
Agtr2 angiotensin II receptor, type 2 0.058
Rp1 retinitis pigmentosa 1 (human) 0.058
Psca prostate stem cell antigen 0.055
Fgfbp1 fibroblast growth factor binding protein 1 0.055
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.054
Sstr4 somatostatin receptor 4 0.053
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.053
Ubl4b ubiquitin-like 4B 0.052
Npy2r neuropeptide Y receptor Y2 0.049
Dlx6 distal-less homeobox 6 0.049
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.049
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.048
Hand2 heart and neural crest derivatives expressed transcript 2 0.047
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.047
Pvalb parvalbumin 0.047
Clcnka chloride channel Ka 0.046
Fgf14 fibroblast growth factor 14 0.045
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.045
Tff1 trefoil factor 1 0.044
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.043
Plg plasminogen 0.043
Hpca hippocalcin 0.043
Pygm muscle glycogen phosphorylase 0.042
Ccr10 chemokine (C-C motif) receptor 10 0.042
Prkce protein kinase C, epsilon 0.042
Nefm neurofilament, medium polypeptide 0.042
Rrh retinal pigment epithelium derived rhodopsin homolog 0.042
Angpt4 angiopoietin 4 0.041
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.040
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.040
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.040
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.039
Dtna dystrobrevin alpha 0.039
Adrb1 adrenergic receptor, beta 1 0.039
Gpr83 G protein-coupled receptor 83 0.038
Defa-rs2 defensin, alpha, related sequence 2 0.038
Tlx2 T-cell leukemia, homeobox 2 0.037
Theg testicular haploid expressed gene 0.037
A530016L24Rik RIKEN cDNA A530016L24 gene 0.035
Pspn persephin 0.035
Foxb2 forkhead box B2 0.035
Lalba lactalbumin, alpha 0.035
Krtap5-1 keratin associated protein 5-1 0.034
BC100451 cDNA sequence BC100451 0.034
Pgr progesterone receptor 0.034
Tank TRAF family member-associated Nf-kappa B activator 0.034
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.034
Bsnd Bartter syndrome, infantile, with sensorineural deafness (Barttin) 0.033
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Rattus norvegicus
Name Description Probability Func Analog Organism
Bcl2 B-cell CLL/lymphoma 2 0.049
Aldoa aldolase A, fructose-bisphosphate 0.037
Rab1b RAB1B, member RAS oncogene family 0.032
LOC100134871 beta globin minor gene 0.029
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.023
Cxcl10 chemokine (C-X-C motif) ligand 10 0.021
Nrcam neuronal cell adhesion molecule 0.021
Rorb RAR-related orphan receptor B 0.020
Isl2 ISL LIM homeobox 2 0.020
Ccl2 chemokine (C-C motif) ligand 2 0.019
Rsad2 radical S-adenosyl methionine domain containing 2 0.019
Fam70b family with sequence similarity 70, member B 0.017
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.016
Icam1 intercellular adhesion molecule 1 0.015
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.015
Ngf nerve growth factor (beta polypeptide) 0.014
Map2 microtubule-associated protein 2 0.014
Phkg1 phosphorylase kinase, gamma 1 0.014
Il6 interleukin 6 0.013
Prkca protein kinase C, alpha 0.013
Prpg1 proline-rich proteoglycan 1 0.013
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.013
Adrb2 adrenergic, beta-2-, receptor, surface 0.013
Cd83 CD83 molecule 0.013
Ltb4r2 leukotriene B4 receptor 2 0.013
Cxcl2 chemokine (C-X-C motif) ligand 2 0.013
Musk muscle, skeletal, receptor tyrosine kinase 0.012
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.012
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.012
Irf1 interferon regulatory factor 1 0.012
Hapln1 hyaluronan and proteoglycan link protein 1 0.012
Eef2 eukaryotic translation elongation factor 2 0.011
Fgfr2 fibroblast growth factor receptor 2 0.011
Cga glycoprotein hormones, alpha polypeptide 0.011
Rims1 regulating synaptic membrane exocytosis 1 0.011
Dlg4 discs, large homolog 4 (Drosophila) 0.011
Nfasc neurofascin 0.010
Tgm1 transglutaminase 1, K polypeptide 0.010
Pnlip pancreatic lipase 0.010