The network for 'maintenance of protein location' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

maintenance of protein location

Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.

Name Description Probability Func Analog Organism
DAD2 Dad2p 0.884
SPC34 Spc34p 0.876
ASK1 Ask1p 0.857
DUO1 Duo1p 0.757
DAD4 Dad4p 0.755
ERP5 Erp5p 0.537
DAM1 Dam1p 0.513
SPC19 Spc19p 0.431
DAD1 Dad1p 0.417
HSK3 Hsk3p 0.405
VPS17 Vps17p 0.297
CKS1 Cks1p 0.225
CLB6 Clb6p 0.217
VPS5 Vps5p 0.204
DAD3 Dad3p 0.187
NKP2 Nkp2p 0.172
SPC29 Spc29p 0.170
CAP1 Cap1p 0.166
RER1 Rer1p 0.157
VIK1 Vik1p 0.157
CDC28 Cdc28p 0.154
OST2 Ost2p 0.151
SWE1 Swe1p 0.144
RHO1 Rho1p 0.143
CHL4 Chl4p 0.121
VPS35 Vps35p 0.120
IST1 Ist1p 0.118
DSN1 Dsn1p 0.118
IML3 Iml3p 0.117
TID3 Tid3p 0.113
VPS29 Vps29p 0.110
MIF2 Mif2p 0.107
SHE1 She1p 0.107
KIP1 Kip1p 0.105
VPS34 Vps34p 0.098
CSE4 Cse4p 0.094
FIN1 Fin1p 0.094
VPS38 Vps38p 0.091
CDC20 Cdc20p 0.091
BMH1 Bmh1p 0.087
MCM21 Mcm21p 0.087
RNR2 Rnr2p 0.085
TED1 Ted1p 0.084
MTW1 Mtw1p 0.082
AIM7 Aim7p 0.079
ERP2 Erp2p 0.078
NNF1 Nnf1p 0.077
COQ5 Coq5p 0.076
NDD1 Ndd1p 0.075
VAC8 Vac8p 0.074
BUB3 Bub3p 0.073
CLB4 Clb4p 0.073
CIN8 Cin8p 0.070
PEP1 Pep1p 0.069
NBL1 Nbl1p 0.069
GAL10 Gal10p 0.067
CSF1 Csf1p 0.065
VPS74 Vps74p 0.065
YPI1 Ypi1p 0.064
GAL80 Gal80p 0.064
RPN14 Rpn14p 0.063
SBA1 Sba1p 0.063
CLN1 Cln1p 0.063
NAB3 Nab3p 0.063
HOC1 Hoc1p 0.063
CIN2 Cin2p 0.062
EMP24 Emp24p 0.062
VPS25 Vps25p 0.062
SCJ1 Scj1p 0.061
OKP1 Okp1p 0.059
CDC48 Cdc48p 0.059
VTA1 Vta1p 0.059
HDA2 Hda2p 0.059
YPL014W hypothetical protein 0.058
SAK1 Sak1p 0.057
SPC97 Spc97p 0.056
PIN4 Pin4p 0.055
CLB2 Clb2p 0.055
SAC7 Sac7p 0.055
CLB5 Clb5p 0.054
APL6 Apl6p 0.054
MDM20 Mdm20p 0.054
KAR9 Kar9p 0.053
VPS28 Vps28p 0.053
KAR3 Kar3p 0.053
YBR096W hypothetical protein 0.050
IQG1 Iqg1p 0.050
SHP1 Shp1p 0.049
TLG2 Tlg2p 0.049
EXO84 Exo84p 0.048
GBP2 Gbp2p 0.048
MVP1 Mvp1p 0.048
ILM1 Ilm1p 0.048
RHO5 Rho5p 0.048
APE3 Ape3p 0.047
KIN2 Kin2p 0.047
YCK1 Yck1p 0.047
AMN1 Amn1p 0.047
NUF2 Nuf2p 0.046
YMR1 Ymr1p 0.046
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.369
cup-2 Protein CUP-2 0.283
hsp-1 Protein HSP-1 0.270
spdl-1 Protein SPDL-1 0.256
tam-1 Protein TAM-1 0.233
ubxn-4 Protein UBXN-4 0.195
hcp-2 Protein HCP-2 0.190
tba-2 Protein TBA-2 0.181
pha-4 Protein PHA-4 0.179
mcm-7 Protein MCM-7 0.165
klp-19 Protein KLP-19 0.157
hmg-1.2 Protein HMG-1.2 0.148
elt-6 Protein ELT-6 0.131
mcm-2 Protein MCM-2 0.130
cnd-1 Protein CND-1 0.115
hcp-4 Protein HCP-4 0.115
rod-1 Protein ROD-1 0.115
T19H12.2 Protein T19H12.2 0.110
rab-1 Protein RAB-1 0.108
atl-1 Protein ATL-1 0.101
eff-1 Protein EFF-1 0.090
unc-70 Protein UNC-70 0.090
knl-1 Protein KNL-1 0.084
bmk-1 Protein BMK-1 0.082
stam-1 Protein STAM-1 0.075
tbb-2 Protein TBB-2 0.074
zfp-1 Protein ZFP-1 0.073
chc-1 Protein CHC-1 0.068
rbc-1 Protein RBC-1 0.067
pdi-3 Protein PDI-3 0.066
spk-1 Protein SPK-1 0.065
F39G3.3 Protein F39G3.3 0.065
cls-2 Protein CLS-2 0.062
dcr-1 Protein DCR-1 0.060
let-2 Protein LET-2 0.059
rpn-1 Protein RPN-1 0.058
ztf-7 Protein ZTF-7 0.057
emb-30 Protein EMB-30 0.055
F33H2.5 Protein F33H2.5 0.053
him-10 Protein HIM-10 0.052
T09B9.4 Protein T09B9.4 0.050
gpr-1 Protein GPR-1 0.050
cyb-2.2 Protein CYB-2.2 0.049
flh-1 Protein FLH-1 0.049
icp-1 Protein ICP-1 0.047
set-16 Protein SET-16 0.046
lin-13 Protein LIN-13 0.046
air-2 Protein AIR-2 0.046
fzy-1 Protein FZY-1 0.046
acs-4 Protein ACS-4 0.045
aspm-1 Protein ASPM-1 0.045
T07C4.10 Protein T07C4.10 0.044
hlh-1 Protein HLH-1 0.044
bub-1 Protein BUB-1 0.044
sago-1 Protein SAGO-1 0.044
knl-2 Protein KNL-2 0.044
zyg-9 Protein ZYG-9 0.043
dsh-2 Protein DSH-2 0.041
rgs-7 Protein RGS-7 0.040
mep-1 Protein MEP-1 0.040
math-33 Protein MATH-33 0.040
prp-8 Protein PRP-8 0.039
lap-2 Protein LAP-2 0.039
eef-1A.1 Protein EEF-1A.1 0.037
ZC434.8 Protein ZC434.8 0.037
hnd-1 Protein HND-1 0.037
mcm-6 Protein MCM-6 0.035
unc-83 Protein UNC-83 0.035
spd-2 Protein SPD-2 0.035
pop-1 Protein POP-1 0.034
pcn-1 Protein PCN-1 0.034
alg-2 Protein ALG-2 0.034
CELE_R06A4.2 Protein R06A4.2 0.033
chd-7 Protein CHD-7 0.033
hcp-1 Protein HCP-1 0.033
tbb-1 Protein TBB-1 0.032
smc-3 Protein SMC-3 0.031
ZK507.6 Protein ZK507.6 0.030
ugt-23 Protein UGT-23 0.029
sar-1 Protein SAR-1 0.029
ten-1 Protein TEN-1 0.028
pry-1 Protein PRY-1 0.028
R05D3.2 Protein R05D3.2 0.027
uaf-1 Protein UAF-1 0.027
F52G3.1 Protein F52G3.1 0.026
F33H2.3 Protein F33H2.3 0.026
F56D2.6 Protein F56D2.6 0.026
ttm-4 Protein TTM-4 0.026
cyb-1 Protein CYB-1 0.026
lin-12 Protein LIN-12 0.025
K10C8.3 Protein K10C8.3 0.025
tag-353 Protein TAG-353 0.025
clic-1 Protein CLIC-1 0.025
pod-1 Protein POD-1 0.025
R11A8.7 Protein R11A8.7 0.025
imp-2 Protein IMP-2 0.025
lin-33 Protein LIN-33 0.025
H11E01.3 Protein H11E01.3 0.025
gei-8 Protein GEI-8 0.024
shc-2 Protein SHC-2 0.024
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Myb Myb oncogene-like 0.750
aop anterior open 0.707
cno canoe 0.591
chic chickadee 0.579
ctp cut up 0.492
zip zipper 0.490
rok Rho-kinase 0.483
Chc Clathrin heavy chain 0.467
fu fused 0.461
Cdc42 CG12530 gene product from transcript CG12530-RA 0.335
mys myospheroid 0.299
egl egalitarian 0.283
ena enabled 0.279
Mer Merlin 0.239
cmet CENP-meta 0.232
sqh spaghetti squash 0.221
emc extra macrochaetae 0.220
flw flapwing 0.205
ci cubitus interruptus 0.177
pim pimples 0.166
Rab5 Rab-protein 5 0.154
fog folded gastrulation 0.142
ana3 anastral spindle 3 0.131
Pp2A-29B Protein phosphatase 2A at 29B 0.130
tum tumbleweed 0.126
Sas-4 CG10061 gene product from transcript CG10061-RA 0.124
aux auxillin 0.123
Stim Stromal interaction molecule 0.121
usp ultraspiracle 0.121
p120ctn Adherens junction protein p120 0.121
shg shotgun 0.115
mew multiple edematous wings 0.112
trc tricornered 0.110
Abl Abl tyrosine kinase 0.101
Cul-2 Cullin-2 0.094
mit(1)15 mitotic 15 0.093
gish gilgamesh 0.093
msn misshapen 0.087
pav pavarotti 0.086
Poc1 Proteome of centrioles 1 0.083
asp abnormal spindle 0.080
Sep2 Septin-2 0.079
dsh dishevelled 0.076
RYBP Ring and YY1 Binding Protein 0.075
arm armadillo 0.074
Cenp-C CG31258 gene product from transcript CG31258-RA 0.073
sle slender lobes 0.073
CycA Cyclin A 0.069
bif bifocal 0.067
Jra Jun-related antigen 0.067
CG7830 CG7830 gene product from transcript CG7830-RA 0.066
alphaTub67C alpha-Tubulin at 67C 0.063
Dsor1 Downstream of raf1 0.063
ncd non-claret disjunctional 0.061
Pvr PDGF- and VEGF-receptor related 0.058
klar klarsicht 0.058
trio CG18214 gene product from transcript CG18214-RA 0.057
put punt 0.057
Aly CG1101 gene product from transcript CG1101-RA 0.055
stg string 0.055
Rho1 CG8416 gene product from transcript CG8416-RB 0.054
Rab11 Rab-protein 11 0.052
CG1943 CG1943 gene product from transcript CG1943-RA 0.052
Klp10A CG1453 gene product from transcript CG1453-RA 0.050
tws twins 0.049
Eb1 CG3265 gene product from transcript CG3265-RF 0.049
Taf8 TBP-associated factor 8 0.048
baz bazooka 0.048
ttv tout-velu 0.047
G-ialpha65A G protein alphai subunit 65A 0.046
mbc myoblast city 0.045
asl asterless 0.044
fzy fizzy 0.044
mars CG17064 gene product from transcript CG17064-RB 0.044
armi armitage 0.043
Src42A Src oncogene at 42A 0.043
Abi Abelson interacting protein 0.042
ph-p polyhomeotic proximal 0.041
Rheb CG1081 gene product from transcript CG1081-RA 0.040
CycB Cyclin B 0.040
Gug Grunge 0.039
Cks30A Cyclin-dependent kinase subunit 30A 0.039
Tip60 CG6121 gene product from transcript CG6121-RA 0.038
PRL-1 CG4993 gene product from transcript CG4993-RB 0.038
Ras85D Ras oncogene at 85D 0.037
Cp110 CG14617 gene product from transcript CG14617-RB 0.037
lqf liquid facets 0.035
sgg shaggy 0.035
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.035
CycB3 Cyclin B3 0.033
CG9053 CG9053 gene product from transcript CG9053-RA 0.032
lkb1 CG9374 gene product from transcript CG9374-RJ 0.032
wisp wispy 0.032
dia diaphanous 0.031
ens ensconsin 0.031
l(2)gl lethal (2) giant larvae 0.030
Sos Son of sevenless 0.030
Dhc64C Dynein heavy chain 64C 0.029
Arp14D Actin-related protein 14D 0.029
cnk connector enhancer of ksr 0.029
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.914
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.912
SMAD2 SMAD family member 2 0.875
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.836
GSK3B glycogen synthase kinase 3 beta 0.778
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.775
CKAP5 cytoskeleton associated protein 5 0.764
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.709
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.664
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.603
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.597
CENPE centromere protein E, 312kDa 0.580
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.562
KIF23 kinesin family member 23 0.555
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.553
NDC80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.538
SYNE1 spectrin repeat containing, nuclear envelope 1 0.534
RACGAP1 Rac GTPase activating protein 1 0.499
SMAD4 SMAD family member 4 0.478
NUF2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.437
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.377
SUN1 Sad1 and UNC84 domain containing 1 0.372
RBL1 retinoblastoma-like 1 (p107) 0.370
PRC1 protein regulator of cytokinesis 1 0.343
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.339
RHOA ras homolog gene family, member A 0.334
ZWINT ZW10 interactor 0.329
CDC25B cell division cycle 25 homolog B (S. pombe) 0.326
ENG endoglin 0.318
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.310
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.309
CKS2 CDC28 protein kinase regulatory subunit 2 0.305
PLK1 polo-like kinase 1 0.289
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.273
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.254
CREBBP CREB binding protein 0.251
BMP2 bone morphogenetic protein 2 0.248
ZMYND11 zinc finger, MYND-type containing 11 0.230
SFN stratifin 0.227
FN1 fibronectin 1 0.216
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.212
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.207
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 0.206
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.196
CEP55 centrosomal protein 55kDa 0.194
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.193
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.191
ANLN anillin, actin binding protein 0.190
MSN moesin 0.182
FKBP1A FK506 binding protein 1A, 12kDa 0.181
ZNF84 zinc finger protein 84 0.178
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.170
CSNK1A1 casein kinase 1, alpha 1 0.167
SUN2 Sad1 and UNC84 domain containing 2 0.164
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.159
MIS12 MIS12, MIND kinetochore complex component, homolog (S. pombe) 0.159
APC adenomatous polyposis coli 0.156
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.154
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.142
CBX5 chromobox homolog 5 0.141
ECT2 epithelial cell transforming sequence 2 oncogene 0.139
FLNA filamin A, alpha 0.138
HIPK3 homeodomain interacting protein kinase 3 0.137
FLNB filamin B, beta 0.136
ACTN1 actinin, alpha 1 0.136
SYNE2 spectrin repeat containing, nuclear envelope 2 0.135
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.129
SPC25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.128
YAP1 Yes-associated protein 1 0.124
DMD dystrophin 0.121
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.118
TLN1 talin 1 0.115
NUP85 nucleoporin 85kDa 0.114
ERBB2IP erbb2 interacting protein 0.112
CASC5 cancer susceptibility candidate 5 0.111
ZFYVE9 zinc finger, FYVE domain containing 9 0.110
PEX19 peroxisomal biogenesis factor 19 0.109
MYH9 myosin, heavy chain 9, non-muscle 0.106
TBCD tubulin folding cofactor D 0.105
VCAN versican 0.105
IQGAP1 IQ motif containing GTPase activating protein 1 0.104
PSEN1 presenilin 1 0.104
CDK1 cyclin-dependent kinase 1 0.103
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.101
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.096
IGF2R insulin-like growth factor 2 receptor 0.094
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.092
SPC24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.091
KIF14 kinesin family member 14 0.090
CDC25A cell division cycle 25 homolog A (S. pombe) 0.088
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.087
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.086
PEX5 peroxisomal biogenesis factor 5 0.086
MARCH7 membrane-associated ring finger (C3HC4) 7 0.086
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.084
BBS4 Bardet-Biedl syndrome 4 0.084
KIF18A kinesin family member 18A 0.083
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.082
ZNF585A zinc finger protein 585A 0.081
PCM1 pericentriolar material 1 0.080
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Pdia3 protein disulfide isomerase family A, member 3 0.112
LOC100362824 caveolin 2-like 0.109
Strn striatin, calmodulin binding protein 0.052
Pdia6 protein disulfide isomerase family A, member 6 0.050
Cav2 caveolin 2 0.049
Traf4af1 TRAF4 associated factor 1 0.032
Cav1 caveolin 1, caveolae protein 0.030
Arf1 ADP-ribosylation factor 1 0.026
Hsp90b1 heat shock protein 90, beta, member 1 0.022
Manf mesencephalic astrocyte-derived neurotrophic factor 0.021
Arl1 ADP-ribosylation factor-like 1 0.013
Pttg1 pituitary tumor-transforming 1 0.012
Kif22 kinesin family member 22 0.012
Lrrc59 leucine rich repeat containing 59 0.012
St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.012
Ube2c ubiquitin-conjugating enzyme E2C 0.011