The network for 'aging' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

aging

A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SIR2 Sir2p 0.681
RFA1 Rfa1p 0.591
AQY2 Aqy2p 0.354
SIR4 Sir4p 0.315
CDC25 Cdc25p 0.302
FUS3 Fus3p 0.285
CPR1 Cpr1p 0.276
CDC4 Cdc4p 0.264
YAP1 Yap1p 0.256
YAK1 Yak1p 0.248
MIG1 Mig1p 0.247
SIN3 Sin3p 0.242
BEM3 Bem3p 0.242
GUT2 Gut2p 0.230
SNF1 Snf1p 0.225
AIM17 Aim17p 0.217
TEL1 Tel1p 0.215
PHB2 Phb2p 0.198
NDI1 Ndi1p 0.189
MIG2 Mig2p 0.182
CSR2 Csr2p 0.174
VHS1 Vhs1p 0.171
SLA2 Sla2p 0.164
DBF2 Dbf2p 0.160
CAK1 Cak1p 0.159
HDA2 Hda2p 0.152
YAT1 Yat1p 0.150
ERR1 Err1p 0.150
STE5 Ste5p 0.149
TOR1 Tor1p 0.145
ENO2 Eno2p 0.143
DIG1 Dig1p 0.139
MOB1 Mob1p 0.136
MSN4 Msn4p 0.136
HAL5 Hal5p 0.134
GIS4 Gis4p 0.133
GLN3 Gln3p 0.131
RPN4 Rpn4p 0.128
TPS2 Tps2p 0.122
ERR2 Err2p 0.121
SCC4 Scc4p 0.118
PHB1 Phb1p 0.118
CUP9 Cup9p 0.113
NET1 Net1p 0.112
MMS22 Mms22p 0.112
LYS5 Lys5p 0.111
POG1 Pog1p 0.111
DNA2 Dna2p 0.111
MNN9 Mnn9p 0.110
SPA2 Spa2p 0.110
VID24 Vid24p 0.109
BCK2 Bck2p 0.108
TOR2 Tor2p 0.106
TDH3 Tdh3p 0.106
WHI2 Whi2p 0.106
MEC1 Mec1p 0.101
FOB1 Fob1p 0.100
HXK2 Hxk2p 0.099
SKN7 Skn7p 0.098
INP52 Inp52p 0.097
YKL187C hypothetical protein 0.096
GIS1 Gis1p 0.096
MIG3 Mig3p 0.095
DCS1 Dcs1p 0.094
POR1 Por1p 0.092
SIC1 Sic1p 0.092
TCP1 Tcp1p 0.091
DPB11 Dpb11p 0.091
ALD6 Ald6p 0.091
RRM3 Rrm3p 0.090
DEF1 Def1p 0.090
NUM1 Num1p 0.090
SIR3 Sir3p 0.089
RAD51 Rad51p 0.087
SAK1 Sak1p 0.086
TRR1 Trr1p 0.086
PUT2 Put2p 0.086
YKU80 Yku80p 0.085
HMO1 Hmo1p 0.084
IZH3 Izh3p 0.082
LAC1 Lac1p 0.082
KAP95 Kap95p 0.082
ACO1 Aco1p 0.081
DOT6 Dot6p 0.080
HXT3 Hxt3p 0.078
ADY2 Ady2p 0.078
CKA2 Cka2p 0.078
HSE1 Hse1p 0.077
XDJ1 Xdj1p 0.076
EXO1 Exo1p 0.075
ASF1 Asf1p 0.075
BAS1 Bas1p 0.075
POL2 Pol2p 0.075
POP2 Pop2p 0.074
LAG1 Lag1p 0.072
RLM1 Rlm1p 0.071
AVO1 Avo1p 0.071
HSV2 Hsv2p 0.070
MDV1 Mdv1p 0.070
YML082W hypothetical protein 0.068
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
cts-1 Protein CTS-1 0.696
npl-4.2 Protein NPL-4.2 0.657
par-5 Protein PAR-5 0.630
H28O16.1 Protein H28O16.1 0.623
nuo-3 Protein NUO-3 0.617
T20H4.5 Protein T20H4.5 0.608
npl-4.1 Protein NPL-4.1 0.584
vps-33.2 Protein VPS-33.2 0.579
apy-1 Protein APY-1 0.524
mpk-1 Protein MPK-1 0.523
F01G4.6 Protein F01G4.6 0.510
pmk-1 Protein PMK-1 0.504
sams-1 Protein SAMS-1 0.502
tbc-2 Protein TBC-2 0.484
CELE_H28G03.1 Protein H28G03.1 0.482
CELE_F59C6.5 Protein F59C6.5 0.476
atp-5 Protein ATP-5 0.473
ZK484.1 Protein ZK484.1 0.473
ifa-1 Protein IFA-1 0.472
mat-3 Protein MAT-3 0.472
pkg-1 Protein PKG-1 0.469
lag-1 Protein LAG-1 0.469
vps-33.1 Protein VPS-33.1 0.469
pmt-1 Protein PMT-1 0.465
ram-2 Protein RAM-2 0.463
F37C12.3 Protein F37C12.3 0.461
sdhb-1 Protein SDHB-1 0.460
rpn-2 Protein RPN-2 0.458
CELE_F46F2.3 Protein F46F2.3 0.456
rpl-13 Protein RPL-13 0.454
F26E4.3 Protein F26E4.3 0.453
T11G6.8 Protein T11G6.8 0.453
ptr-14 Protein PTR-14 0.452
atfs-1 Protein ATFS-1 0.452
unc-62 Protein UNC-62 0.450
acdh-3 Protein ACDH-3 0.449
tbb-4 Protein TBB-4 0.448
ahcy-1 Protein AHCY-1 0.447
R53.4 Protein R53.4 0.446
col-144 Protein COL-144 0.444
prx-19 Protein PRX-19 0.440
col-154 Protein COL-154 0.434
gld-1 Protein GLD-1 0.434
gst-7 Protein GST-7 0.433
cct-7 Protein CCT-7 0.432
sem-5 Protein SEM-5 0.430
cye-1 Protein CYE-1 0.430
elo-6 Protein ELO-6 0.429
mig-15 Protein MIG-15 0.428
daf-11 Protein DAF-11 0.425
ptr-4 Protein PTR-4 0.424
mrp-5 Protein MRP-5 0.420
dlc-1 Protein DLC-1 0.418
egal-1 Protein EGAL-1 0.418
col-17 Protein COL-17 0.418
mev-1 Protein MEV-1 0.416
lys-1 Protein LYS-1 0.416
eef-1A.1 Protein EEF-1A.1 0.415
ttr-48 Protein TTR-48 0.415
C47B2.2 Protein C47B2.2 0.414
CELE_C49C3.7 Protein C49C3.7 0.413
fkh-2 Protein FKH-2 0.413
icd-1 Protein ICD-1 0.413
hda-1 Protein HDA-1 0.410
sgt-1 Protein SGT-1 0.410
hsp-16.41 Protein HSP-16.41 0.407
B0495.7 Protein B0495.7 0.406
pccb-1 Protein PCCB-1 0.404
htp-3 Protein HTP-3 0.403
R05G6.7 Protein R05G6.7 0.403
F53F10.2 Protein F53F10.2 0.401
vha-8 Protein VHA-8 0.399
F32A5.3 Protein F32A5.3 0.398
pqn-44 Protein PQN-44 0.397
nuaf-1 Protein NUAF-1 0.397
atp-2 Protein ATP-2 0.395
rpl-7 Protein RPL-7 0.395
F22D3.2 Protein F22D3.2 0.395
drp-1 Protein DRP-1 0.394
tba-2 Protein TBA-2 0.393
col-157 Protein COL-157 0.393
F08G5.6 Protein F08G5.6 0.390
prdx-3 Protein PRDX-3 0.388
nduf-7 Protein NDUF-7 0.388
cyp-34A9 Protein CYP-34A9 0.387
mrck-1 Protein MRCK-1 0.387
cyc-2.1 Protein CYC-2.1 0.387
T06D8.5 Protein T06D8.5 0.385
sucl-2 Protein SUCL-2 0.383
hlh-2 Protein HLH-2 0.382
pbs-4 Protein PBS-4 0.381
M01F1.3 Protein M01F1.3 0.379
CELE_C27A7.1 Protein C27A7.1 0.379
rol-8 Protein ROL-8 0.377
cri-3 Protein CRI-3 0.376
aap-1 Protein AAP-1 0.375
hmgr-1 Protein HMGR-1 0.374
rpl-35 Protein RPL-35 0.374
cpb-1 Protein CPB-1 0.372
npp-15 Protein NPP-15 0.370
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.863
shhb sonic hedgehog b 0.829
hspa5 heat shock protein 5 0.826
uqcrc1 ubiquinol-cytochrome c reductase core protein I 0.807
rxrab retinoid x receptor, alpha b 0.790
psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.770
rpl35 ribosomal protein L35 0.759
fgfr1a fibroblast growth factor receptor 1a 0.758
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.750
vcp valosin containing protein 0.745
plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.720
gpia glucose phosphate isomerase a 0.717
hspb12 heat shock protein, alpha-crystallin-related, b12 0.715
zgc:111961 zgc:111961 0.697
rpsa ribosomal protein SA 0.696
aqp1a.1 aquaporin 1a, tandem duplicate 1 0.695
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.695
aldocb aldolase C, fructose-bisphosphate, b 0.685
psma6a proteasome (prosome, macropain) subunit, alpha type, 6a 0.682
bhlhe40 basic helix-loop-helix family, member e40 0.675
aqp3a aquaporin 3a 0.670
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.670
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.666
egr2b early growth response 2b 0.666
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.666
jun jun proto-oncogene 0.659
tfr1a transferrin receptor 1a 0.658
fgfrl1a fibroblast growth factor receptor-like 1a 0.654
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.642
rpl21 ribosomal protein L21 0.640
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.634
cldnc claudin c 0.619
rpl13a ribosomal protein L13a 0.610
rpl36a ribosomal protein L36A 0.609
npy8br neuropeptide Y receptor Y8b 0.608
pabpc1a poly A binding protein, cytoplasmic 1 a 0.607
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.604
pdhb pyruvate dehydrogenase (lipoamide) beta 0.603
psmd4b proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b 0.601
chrnd cholinergic receptor, nicotinic, delta polypeptide 0.601
runx2b runt-related transcription factor 2b 0.599
rpl12 ribosomal protein L12 0.593
aco2 aconitase 2, mitochondrial 0.591
etfa electron-transfer-flavoprotein, alpha polypeptide 0.590
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.590
hk1 hexokinase 1 0.588
prox1 prospero-related homeobox gene 1 0.582
ca2 carbonic anhydrase II 0.579
mef2a myocyte enhancer factor 2a 0.578
mcts1 malignant T cell amplified sequence 1 0.576
ppia peptidylprolyl isomerase A (cyclophilin A) 0.573
psmb1 proteasome (prosome, macropain) subunit, beta type, 1 0.569
shbg sex hormone binding globulin 0.569
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.568
aqp8a.1 aquaporin 8a, tandem duplicate 1 0.568
itgb1b.2 integrin, beta 1b.2 0.565
th tyrosine hydroxylase 0.562
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.553
mt2 metallothionein 2 0.550
acvr2a activin receptor IIa 0.547
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.533
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.532
rps18 ribosomal protein S18 0.525
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.525
vdra vitamin D receptor a 0.523
zgc:77262 zgc:77262 0.520
hspa4b heat shock protein 4b 0.517
rps11 ribosomal protein S11 0.517
wnt10a wingless-type MMTV integration site family, member 10a 0.516
sdc2 syndecan 2 0.515
osr2 odd-skipped related 2 (Drosophila) 0.512
polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.511
dag1 dystroglycan 1 0.510
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.506
pvalb8 parvalbumin 8 0.505
mapk1 mitogen-activated protein kinase 1 0.505
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.504
six4b sine oculis homeobox homolog 4b 0.503
ucp1 uncoupling protein 1 0.501
itgb1b integrin, beta 1b 0.501
ctsl1a cathepsin L, 1 a 0.498
ndufs8a NADH dehydrogenase (ubiquinone) Fe-S protein 8a 0.494
atp6v1al ATPase, H+ transporting, lysosomal V1 subunit A, like 0.491
met met proto-oncogene (hepatocyte growth factor receptor) 0.491
eef2b eukaryotic translation elongation factor 2b 0.489
fabp3 fatty acid binding protein 3, muscle and heart 0.484
fabp7a fatty acid binding protein 7, brain, a 0.482
rxrga retinoid x receptor, gamma a 0.479
eif5a eukaryotic translation initiation factor 5A 0.478
dmrt2a doublesex and mab-3 related transcription factor 2a 0.477
ck2b casein kinase 2 beta 0.476
usp5 ubiquitin specific protease 5 0.476
notch1b notch homolog 1b 0.476
chpf chondroitin polymerizing factor 0.474
insrb insulin receptor b 0.463
cldn5a claudin 5a 0.462
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.462
eef1g eukaryotic translation elongation factor 1 gamma 0.455
spock3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.455
ppial peptidylprolyl isomerase A, like 0.454
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
rpr reaper 0.998
EcR Ecdysone receptor 0.991
Akt1 CG4006 gene product from transcript CG4006-RA 0.965
Thor CG8846 gene product from transcript CG8846-RA 0.965
shi shibire 0.960
lok loki 0.953
Top2 Topoisomerase 2 0.950
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.941
Nf1 Neurofibromin 1 0.940
InR Insulin-like receptor 0.939
Lam Lamin 0.933
chico CG5686 gene product from transcript CG5686-RB 0.931
Tpi Triose phosphate isomerase 0.929
Atg8a Autophagy-specific gene 8a 0.929
G-salpha60A G protein salpha 60A 0.922
Hsp68 Heat shock protein 68 0.911
asp abnormal spindle 0.883
bsk basket 0.881
Rpt4 CG3455 gene product from transcript CG3455-RA 0.873
GLaz Glial Lazarillo 0.871
caz cabeza 0.853
ctp cut up 0.847
Ilp5 Insulin-like peptide 5 0.837
Prx5 Peroxiredoxin 5 0.822
Hsp70Ab Heat-shock-protein-70Ab 0.808
Moe Moesin 0.804
Sod2 Superoxide dismutase 2 (Mn) 0.790
Egfr Epidermal growth factor receptor 0.786
RagA CG11968 gene product from transcript CG11968-RA 0.772
Uba1 Ubiquitin activating enzyme 1 0.765
S6k RPS6-p70-protein kinase 0.759
Atg1 Autophagy-specific gene 1 0.757
l(2)efl lethal (2) essential for life 0.748
Indy I'm not dead yet 0.714
dm diminutive 0.710
Rpt1 CG1341 gene product from transcript CG1341-RA 0.704
Mad Mothers against dpp 0.704
Pink1 PTEN-induced putative kinase 1 0.703
Fatp Fatty acid (long chain) transport protein 0.695
brat brain tumor 0.690
Atpalpha Na pump alpha subunit 0.687
Rheb CG1081 gene product from transcript CG1081-RA 0.686
dj-1beta CG1349 gene product from transcript CG1349-RA 0.677
stv starvin 0.676
Dad Daughters against dpp 0.673
Stat92E Signal-transducer and activator of transcription protein at 92E 0.665
atl atlastin 0.663
Rel Relish 0.644
Smox Smad on X 0.644
norpA no receptor potential A 0.638
Cat Catalase 0.629
dpp decapentaplegic 0.615
MAGE CG10059 gene product from transcript CG10059-RA 0.614
dco discs overgrown 0.608
CG6783 CG6783 gene product from transcript CG6783-RC 0.607
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.601
Hsp26 Heat shock protein 26 0.597
Dcr-2 Dicer-2 0.588
cdc2c CG10498 gene product from transcript CG10498-RC 0.586
POSH Plenty of SH3s 0.583
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.582
p38b CG7393 gene product from transcript CG7393-RA 0.578
CG9350 CG9350 gene product from transcript CG9350-RA 0.556
Pk61C Protein kinase 61C 0.552
Rac1 CG2248 gene product from transcript CG2248-RA 0.544
phl pole hole 0.536
loqs loquacious 0.523
Nrx-IV Neurexin IV 0.513
usp ultraspiracle 0.513
tefu telomere fusion 0.504
drd drop dead 0.494
CG8155 CG8155 gene product from transcript CG8155-RA 0.484
CSN5 COP9 complex homolog subunit 5 0.471
stmA stambha A 0.454
CG42863 CG42863 gene product from transcript CG42863-RB 0.452
foxo forkhead box, sub-group O 0.448
CaMKII Calcium/calmodulin-dependent protein kinase II 0.442
HspB8 CG14207 gene product from transcript CG14207-RB 0.425
Tak1 TGF-beta activated kinase 1 0.423
babo baboon 0.421
Acsl Acyl-CoA synthetase long-chain 0.420
alpha-Man-I alpha Mannosidase I 0.418
CAH1 Carbonic anhydrase 1 0.411
Ilp2 Insulin-like peptide 2 0.411
arm armadillo 0.404
tws twins 0.392
Idh Isocitrate dehydrogenase 0.386
Ide Insulin degrading metalloproteinase 0.383
levy CG17280 gene product from transcript CG17280-RA 0.381
CG12079 CG12079 gene product from transcript CG12079-RA 0.379
ftz-f1 ftz transcription factor 1 0.378
GlyP Glycogen phosphorylase 0.376
daw dawdle 0.372
RecQ4 CG7487 gene product from transcript CG7487-RA 0.359
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.357
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.352
Tsp29Fb Tetraspanin 29Fb 0.352
Top1 Topoisomerase 1 0.350
Hsp22 Heat shock protein 22 0.343
stck steamer duck 0.343
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
TP53 tumor protein p53 0.984
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.982
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.919
CREBBP CREB binding protein 0.900
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.855
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.854
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.853
JUN jun proto-oncogene 0.829
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.815
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.715
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.672
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.644
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.631
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.605
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.582
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.565
POMP proteasome maturation protein 0.557
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.550
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.546
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.543
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 0.540
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.536
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.535
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.511
PABPC1 poly(A) binding protein, cytoplasmic 1 0.511
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.500
KRT15 keratin 15 0.495
HSPA4 heat shock 70kDa protein 4 0.464
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.455
DAXX death-domain associated protein 0.433
CSNK2B casein kinase 2, beta polypeptide 0.421
VCP valosin containing protein 0.415
PARP1 poly (ADP-ribose) polymerase 1 0.414
HSPB1 heat shock 27kDa protein 1 0.391
SYK spleen tyrosine kinase 0.387
RARA retinoic acid receptor, alpha 0.371
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.368
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.368
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.368
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.366
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.364
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.358
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.356
PML promyelocytic leukemia 0.355
SIRT1 sirtuin 1 0.342
EIF3K eukaryotic translation initiation factor 3, subunit K 0.341
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.338
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.323
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.318
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.289
HSPA8 heat shock 70kDa protein 8 0.288
RPS23 ribosomal protein S23 0.288
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.285
FLNA filamin A, alpha 0.277
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.275
EIF4E eukaryotic translation initiation factor 4E 0.269
ARRB1 arrestin, beta 1 0.269
MAPK8 mitogen-activated protein kinase 8 0.266
RPS16 ribosomal protein S16 0.263
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.262
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.258
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.257
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.257
TGFB1 transforming growth factor, beta 1 0.256
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.252
SMAD3 SMAD family member 3 0.238
RPLP0 ribosomal protein, large, P0 0.238
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.232
WDR5 WD repeat domain 5 0.231
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.229
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.228
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.225
DLAT dihydrolipoamide S-acetyltransferase 0.223
GABARAP GABA(A) receptor-associated protein 0.220
BAG3 BCL2-associated athanogene 3 0.219
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.211
ACTB actin, beta 0.208
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.204
EPRS glutamyl-prolyl-tRNA synthetase 0.202
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.200
RXRA retinoid X receptor, alpha 0.200
EP300 E1A binding protein p300 0.198
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.197
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.196
PRDX1 peroxiredoxin 1 0.191
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.190
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.188
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.188
ZFYVE9 zinc finger, FYVE domain containing 9 0.187
RHOA ras homolog gene family, member A 0.187
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.186
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.186
HDAC1 histone deacetylase 1 0.182
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.178
ARRB2 arrestin, beta 2 0.177
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.171
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.170
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 0.169
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.168
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Ccl3 chemokine (C-C motif) ligand 3 0.714
Prdx2 peroxiredoxin 2 0.683
Gstm1 glutathione S-transferase mu 1 0.655
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.618
Cd14 CD14 molecule 0.616
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.583
Reg3g regenerating islet-derived 3 gamma 0.579
Tgfbr2 transforming growth factor, beta receptor II 0.558
Nfasc neurofascin 0.551
Agtr1a angiotensin II receptor, type 1a 0.536
Ccr5 chemokine (C-C motif) receptor 5 0.535
Egr2 early growth response 2 0.534
Mif macrophage migration inhibitory factor 0.526
Ednrb endothelin receptor type B 0.520
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.504
Agtr2 angiotensin II receptor, type 2 0.500
Rara retinoic acid receptor, alpha 0.479
Cd44 Cd44 molecule 0.469
Cxcl10 chemokine (C-X-C motif) ligand 10 0.457
Zyx zyxin 0.455
Jak2 Janus kinase 2 0.448
Fn1 fibronectin 1 0.448
Ccl4 chemokine (C-C motif) ligand 4 0.444
Hspb1 heat shock protein 1 0.438
Phkg1 phosphorylase kinase, gamma 1 0.426
Gstm2 glutathione S-transferase mu 2 0.418
Col1a1 collagen, type I, alpha 1 0.414
Mmp3 matrix metallopeptidase 3 0.396
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.393
Homer3 homer homolog 3 (Drosophila) 0.386
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.384
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.375
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.368
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.367
Irs1 insulin receptor substrate 1 0.366
Calcrl calcitonin receptor-like 0.361
Dcc deleted in colorectal carcinoma 0.361
Plaur plasminogen activator, urokinase receptor 0.358
Cd4 Cd4 molecule 0.356
Prlh prolactin releasing hormone 0.348
Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 0.343
Col3a1 collagen, type III, alpha 1 0.343
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.343
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.343
Ncr1 natural cytotoxicity triggering receptor 1 0.342
LOC305103 cell surface glycoprotein gp42 0.334
Trhr2 thyrotropin releasing hormone receptor 2 0.332
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.330
Dpep1 dipeptidase 1 (renal) 0.329
Ephx1 epoxide hydrolase 1, microsomal 0.324
C1qc complement component 1, q subcomponent, C chain 0.324
Gpx3 glutathione peroxidase 3 0.323
Pmp22 peripheral myelin protein 22 0.322
Psp parotid secretory protein 0.321
Cartpt CART prepropeptide 0.320
Ahr aryl hydrocarbon receptor 0.315
Stat6 signal transducer and activator of transcription 6 0.312
Jak1 Janus kinase 1 0.310
Ghr growth hormone receptor 0.309
Hnf1b HNF1 homeobox B 0.305
Hoxa2 homeo box A2 0.305
Akr1c14 aldo-keto reductase family 1, member C14 0.303
Fgf18 fibroblast growth factor 18 0.303
Clec9a C-type lectin domain family 9, member a 0.302
Cybb cytochrome b-245, beta polypeptide 0.302
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.298
LOC100361864 UDP-glucuronosyltransferase 2B3-like 0.298
Gsta3 glutathione S-transferase A3 0.296
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.293
Sdc3 syndecan 3 0.283
Cd40lg CD40 ligand 0.283
Mchr1 melanin-concentrating hormone receptor 1 0.282
Psmb6 proteasome (prosome, macropain) subunit, beta type 6 0.280
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.280
LOC100362824 caveolin 2-like 0.277
Dcn decorin 0.275
Anxa2 annexin A2 0.272
Oxtr oxytocin receptor 0.272
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.272
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.270
Il1rn interleukin 1 receptor antagonist 0.269
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.269
COX3 cytochrome c oxidase subunit 3 0.268
Flt1 FMS-related tyrosine kinase 1 0.267
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.267
Insrr insulin receptor-related receptor 0.262
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.262
Gfap glial fibrillary acidic protein 0.261
C8b complement component 8, beta polypeptide 0.259
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.258
Cckar cholecystokinin A receptor 0.258
Stat3 signal transducer and activator of transcription 3 0.258
Myo1b myosin Ib 0.257
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.256
Acta2 smooth muscle alpha-actin 0.256
Cyb5a cytochrome b5 type A (microsomal) 0.253
Icam1 intercellular adhesion molecule 1 0.250
Col10a1 collagen, type X, alpha 1 0.247
Cga glycoprotein hormones, alpha polypeptide 0.244
Tpo thyroid peroxidase 0.242