The network for 'cellular response to topologically incorrect protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to topologically incorrect protein

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CDC48 Cdc48p 0.424
STI1 Sti1p 0.183
PMT2 Pmt2p 0.133
RIM21 Rim21p 0.119
PMT1 Pmt1p 0.112
SIS1 Sis1p 0.094
AHA1 Aha1p 0.093
DER1 Der1p 0.090
PMT3 Pmt3p 0.078
MSG5 Msg5p 0.074
PMT5 Pmt5p 0.061
KAR2 Kar2p 0.059
SFB3 Sfb3p 0.053
SCJ1 Scj1p 0.051
RLM1 Rlm1p 0.046
HRD3 Hrd3p 0.045
SGT2 Sgt2p 0.042
IRE1 Ire1p 0.040
MUB1 Mub1p 0.039
SLT2 Slt2p 0.039
MCD4 Mcd4p 0.038
GWT1 Gwt1p 0.038
KRE1 Kre1p 0.038
STE5 Ste5p 0.038
BTN2 Btn2p 0.036
SSM4 Ssm4p 0.035
UBX7 Ubx7p 0.035
SPF1 Spf1p 0.033
BIG1 Big1p 0.033
UFD1 Ufd1p 0.032
SSA1 Ssa1p 0.032
UFD2 Ufd2p 0.031
SCS3 Scs3p 0.029
KTR1 Ktr1p 0.029
SOK2 Sok2p 0.027
UBA1 Uba1p 0.027
SIL1 Sil1p 0.026
URH1 Urh1p 0.026
TRA1 Tra1p 0.026
HMG2 Hmg2p 0.025
BMH1 Bmh1p 0.025
YOL098C hypothetical protein 0.025
JEM1 Jem1p 0.025
SSA2 Ssa2p 0.025
OTU1 Otu1p 0.025
KDX1 Kdx1p 0.025
SEC59 Sec59p 0.024
BST1 Bst1p 0.024
SSE2 Sse2p 0.024
CRP1 Crp1p 0.023
UBR2 Ubr2p 0.023
PAR32 Par32p 0.023
YHR162W hypothetical protein 0.023
PTC4 Ptc4p 0.023
ALG12 Alg12p 0.022
RPN2 Rpn2p 0.022
KRE6 Kre6p 0.022
EUG1 Eug1p 0.022
UBP8 Ubp8p 0.022
CAM1 Cam1p 0.022
HAC1 Hac1p 0.022
YHB1 Yhb1p 0.021
UBR1 Ubr1p 0.021
CNB1 Cnb1p 0.021
CWH41 Cwh41p 0.021
SAC7 Sac7p 0.021
SRD1 Srd1p 0.021
CUR1 Cur1p 0.020
OSH3 Osh3p 0.020
HEM13 Hem13p 0.020
MPT5 Mpt5p 0.020
MPD1 Mpd1p 0.020
YEL047C hypothetical protein 0.020
MOT3 Mot3p 0.020
BFR1 Bfr1p 0.020
SLC1 Slc1p 0.020
YNL155W hypothetical protein 0.020
CUP1-1 Cup1-1p 0.020
ACC1 Acc1p 0.020
OYE2 Oye2p 0.020
RTS2 Rts2p 0.020
INO2 Ino2p 0.020
YLR264C-A hypothetical protein 0.019
YLR162W hypothetical protein 0.019
STE24 Ste24p 0.019
PCL9 Pcl9p 0.019
SPP381 Spp381p 0.019
YPK9 Ypk9p 0.019
ADR1 Adr1p 0.019
OYE3 Oye3p 0.019
USA1 Usa1p 0.019
TAE2 Tae2p 0.018
MMS1 Mms1p 0.018
PBS2 Pbs2p 0.018
LEU2 Leu2p 0.018
CAB3 Cab3p 0.018
FPS1 Fps1p 0.018
CNE1 Cne1p 0.018
YIL151C hypothetical protein 0.018
ASG1 Asg1p 0.018
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
abu-15 Protein ABU-15 0.998
hsp-16.2 Protein HSP-16.2 0.989
hsp-16.41 Protein HSP-16.41 0.988
tag-320 Protein TAG-320 0.980
abu-8 Protein ABU-8 0.972
hsp-16.1 Protein HSP-16.1 0.959
hsp-70 Protein HSP-70 0.957
abu-11 Protein ABU-11 0.947
pqn-54 Protein PQN-54 0.941
hsp-3 Protein HSP-3 0.939
F44E5.4 Protein F44E5.4 0.927
abu-1 Protein ABU-1 0.879
hsp-16.48 Protein HSP-16.48 0.866
dnj-7 Protein DNJ-7 0.797
CELE_T05E11.3 Protein T05E11.3 0.743
abu-6 Protein ABU-6 0.708
abu-10 Protein ABU-10 0.626
Y47D3B.6 Protein Y47D3B.6 0.525
abu-14 Protein ABU-14 0.525
Y94H6A.7 Protein Y94H6A.7 0.522
CELE_F20G2.2 Protein F20G2.2 0.488
lys-1 Protein LYS-1 0.475
pdi-3 Protein PDI-3 0.451
sec-22 Protein SEC-22 0.401
hsp-1 Protein HSP-1 0.374
crt-1 Protein CRT-1 0.365
CELE_Y41C4A.11 Protein Y41C4A.11 0.356
F13E6.5 Protein F13E6.5 0.352
erv-46 Protein ERV-46 0.334
dsc-4 Protein DSC-4 0.332
dct-18 Protein DCT-18 0.312
daf-21 Protein DAF-21 0.306
ifd-1 Protein IFD-1 0.304
pdi-2 Protein PDI-2 0.300
F54E2.1 Protein F54E2.1 0.299
abu-9 Protein ABU-9 0.297
C29F3.7 Protein C29F3.7 0.294
R03C1.1 Protein R03C1.1 0.289
CELE_T06E4.9 Protein T06E4.9 0.289
T10B10.3 Protein T10B10.3 0.289
F41E6.11 Protein F41E6.11 0.266
tufm-1 Protein TUFM-1 0.257
stt-3 Protein STT-3 0.251
cnp-3 Protein CNP-3 0.247
eef-1A.1 Protein EEF-1A.1 0.245
npl-4.2 Protein NPL-4.2 0.243
F08H9.3 Protein F08H9.3 0.221
pqn-63 Protein PQN-63 0.220
npl-4.1 Protein NPL-4.1 0.216
nhr-17 Protein NHR-17 0.213
clk-1 Protein CLK-1 0.208
F10D7.2 Protein F10D7.2 0.190
skn-1 Protein SKN-1 0.187
rsbp-1 Protein RSBP-1 0.187
ckb-2 Protein CKB-2 0.185
CELE_T06E4.8 Protein T06E4.8 0.184
C35B1.5 Protein C35B1.5 0.178
R05F9.6 Protein R05F9.6 0.174
F47G9.1 Protein F47G9.1 0.162
gst-1 Protein GST-1 0.161
lec-10 Protein LEC-10 0.158
acs-4 Protein ACS-4 0.156
grl-7 Protein GRL-7 0.152
rpt-3 Protein RPT-3 0.145
asns-1 Protein ASNS-1 0.145
dre-1 Protein DRE-1 0.144
pqn-57 Protein PQN-57 0.143
ZK686.3 Protein ZK686.3 0.138
suca-1 Protein SUCA-1 0.138
haly-1 Protein HALY-1 0.138
trap-2 Protein TRAP-2 0.135
mdt-28 Protein MDT-28 0.135
paa-1 Protein PAA-1 0.134
F19C7.1 Protein F19C7.1 0.132
ser-3 Protein SER-3 0.128
CELE_Y39B6A.1 Protein Y39B6A.1 0.128
pqn-74 Protein PQN-74 0.126
unc-78 Protein UNC-78 0.126
gale-1 Protein GALE-1 0.121
hsp-17 Protein HSP-17 0.120
M02H5.8 Protein M02H5.8 0.119
CELE_F59B1.8 Protein F59B1.8 0.119
hsp-4 Protein HSP-4 0.119
act-5 Protein ACT-5 0.118
prx-19 Protein PRX-19 0.115
vha-17 Protein VHA-17 0.115
CELE_F19B2.5 Protein F19B2.5 0.115
gsr-1 Protein GSR-1 0.114
Y5H2A.4 Protein Y5H2A.4 0.114
ZK6.11 Protein ZK6.11 0.113
pdi-1 Protein PDI-1 0.112
CELE_T06E4.10 Protein T06E4.10 0.110
pqn-32 Protein PQN-32 0.107
dpf-5 Protein DPF-5 0.106
tba-2 Protein TBA-2 0.106
F08H9.4 Protein F08H9.4 0.104
clc-3 Protein CLC-3 0.104
cut-4 Protein CUT-4 0.103
lec-6 Protein LEC-6 0.103
C52A10.1 Protein C52A10.1 0.100
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
hspa5 heat shock protein 5 1.000
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.992
manf mesencephalic astrocyte-derived neurotrophic factor 0.976
calr calreticulin and calreticulin 0.973
hyou1 hypoxia up-regulated 1 0.962
pdip5 protein disulfide isomerase-related protein (provisional) 0.926
dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.906
tram1 translocating chain-associating membrane protein 1 0.883
dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.866
pdia3 protein disulfide isomerase family A, member 3 0.843
hspd1 heat shock 60kD protein 1 (chaperonin) 0.811
calrl calreticulin like 0.732
calrl2 calreticulin, like 2 0.499
pdia4 protein disulfide isomerase associated 4 0.449
txnrd1 thioredoxin reductase 1 0.382
canx calnexin 0.342
lars leucyl-tRNA synthetase 0.313
syvn1 synovial apoptosis inhibitor 1, synoviolin 0.273
yars tyrosyl-tRNA synthetase 0.261
prkcsh protein kinase C substrate 80K-H 0.248
hsp90a.2 heat shock protein 90-alpha 2 0.230
tmed2 transmembrane emp24 domain trafficking protein 2 0.225
ttna titin a 0.212
tmed9 transmembrane emp24 protein transport domain containing 9 0.182
ccng1 cyclin G1 0.165
ef1a elongation factor 1-alpha 0.131
mbnl2 muscleblind-like 2 (Drosophila) 0.115
hspa4a heat shock protein 4a 0.105
mtdha metadherin a 0.104
herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.104
ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.103
zbtb22b zinc finger and BTB domain containing 22b 0.102
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.100
kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.098
eif4a1a eukaryotic translation initiation factor 4A, isoform 1A 0.095
lonp1 lon peptidase 1, mitochondrial 0.090
zgc:153260 zgc:153260 0.090
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.089
sec61al2 Sec61 alpha like 2 0.089
cdkrap3 CDK5 regulatory subunit associated protein 3 0.089
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.077
tm9sf3 transmembrane 9 superfamily member 3 0.074
zgc:101724 zgc:101724 0.070
copa coatomer protein complex, subunit alpha 0.069
abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 0.068
neb nebulin 0.068
zgc:153286 zgc:153286 0.066
papss2b 3'-phosphoadenosine 5'-phosphosulfate synthase 2b 0.065
lman1 lectin, mannose-binding, 1 0.065
hspa8 heat shock protein 8 0.065
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.064
zgc:162630 zgc:162630 0.064
zgc:56419 zgc:56419 0.064
tmco1 transmembrane and coiled-coil domains 1 0.062
nucb2b nucleobindin 2b 0.059
copb1 coatomer protein complex, subunit beta 1 0.057
nars asparaginyl-tRNA synthetase 0.056
idh3b isocitrate dehydrogenase 3 (NAD+) beta 0.053
alg2 asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) 0.052
atp2a2b ATPase, Ca++ transporting, cardiac muscle, slow twitch 2b 0.052
faf2 Fas associated factor family member 2 0.051
myca myelocytomatosis oncogene a 0.051
cyc1 cytochrome c-1 0.050
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.050
hm13 histocompatibility (minor) 13 0.049
nfe2l2 nuclear factor (erythroid-derived 2)-like 2 0.048
furinb furin (paired basic amino acid cleaving enzyme) b 0.047
vmp1 vacuole membrane protein 1 0.047
ctage5 CTAGE family, member 5 0.047
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.047
mapkapk2a mitogen-activated protein kinase-activated protein kinase 2a 0.046
odc1 ornithine decarboxylase 1 0.045
qars glutaminyl-tRNA synthetase 0.045
copb2 coatomer protein complex, subunit beta 2 0.044
srpr signal recognition particle receptor (docking protein) 0.044
tnni2a.4 troponin I, skeletal, fast 2a.4 0.044
adra2b adrenergic, alpha-2B-, receptor 0.044
mylz3 myosin, light polypeptide 3, skeletal muscle 0.043
tm9sf2 transmembrane 9 superfamily member 2 0.043
grhl2b grainyhead-like 2b (Drosophila) 0.042
herpud2 HERPUD family member 2 0.042
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.042
arf1 ADP-ribosylation factor 1 0.041
adra2a adrenergic, alpha-2A-, receptor 0.040
rpn2 ribophorin II 0.040
tnfsf10l3 tumor necrosis factor (ligand) superfamily, member 10 like 3 0.040
c20orf24 c20orf24 homolog (H. sapiens) 0.039
vmhc ventricular myosin heavy chain 0.039
lap3 leucine aminopeptidase 3 0.038
stt3b STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) 0.038
figla factor in the germline alpha 0.038
os9 amplified in osteosarcoma 0.038
prkri protein-kinase, interferon-inducible double stranded RNA dependent inhibitor 0.038
asna1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.037
sqrdl sulfide quinone reductase-like (yeast) 0.037
pcsk7 proprotein convertase subtilisin/kexin type 7 0.037
xbp1 X-box binding protein 1 0.037
arf2 ADP-ribosylation factor 2 0.037
ucp3 uncoupling protein 3 0.037
pvalb4 parvalbumin 4 0.036
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rab7 Rab-protein 7 0.237
gt giant 0.098
Acsl Acyl-CoA synthetase long-chain 0.089
CG5484 CG5484 gene product from transcript CG5484-RC 0.048
CG12404 CG12404 gene product from transcript CG12404-RA 0.048
Rel Relish 0.046
Xbp1 X box binding protein-1 0.044
Cat Catalase 0.027
CG32581 CG32581 gene product from transcript CG32581-RB 0.025
myoglianin CG1838 gene product from transcript CG1838-RD 0.019
CG1418 CG1418 gene product from transcript CG1418-RA 0.019
CG5276 CG5276 gene product from transcript CG5276-RA 0.019
CG7371 CG7371 gene product from transcript CG7371-RA 0.018
path pathetic 0.017
Pak PAK-kinase 0.017
Ero1L Endoplasmic reticulum oxidoreductin-1-like 0.017
CG30344 CG30344 gene product from transcript CG30344-RA 0.017
Spase25 Spase 25-subunit 0.017
stv starvin 0.016
Rab14 Rab-protein 14 0.016
CaBP1 CG5809 gene product from transcript CG5809-RA 0.016
mrj CG8448 gene product from transcript CG8448-RD 0.015
P58IPK CG8286 gene product from transcript CG8286-RA 0.015
CG11009 CG11009 gene product from transcript CG11009-RB 0.015
CG3061 CG3061 gene product from transcript CG3061-RA 0.015
Syx18 Syntaxin 18 0.015
garz gartenzwerg 0.015
Vhl von Hippel-Lindau 0.014
KdelR KDEL receptor 0.013
CG7830 CG7830 gene product from transcript CG7830-RA 0.013
opa1-like optic atrophy 1-like 0.013
Der-1 Derlin-1 0.012
CG10158 CG10158 gene product from transcript CG10158-RA 0.012
Syx17 Syntaxin 17 0.012
CG30392 CG30392 gene product from transcript CG30392-RA 0.011
CG11857 CG11857 gene product from transcript CG11857-RA 0.011
CG15111 CG15111 gene product from transcript CG15111-RB 0.011
CG7945 CG7945 gene product from transcript CG7945-RC 0.011
bc10 CG4867 gene product from transcript CG4867-RA 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.999
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.994
VCP valosin containing protein 0.994
PDIA3 protein disulfide isomerase family A, member 3 0.991
P4HB prolyl 4-hydroxylase, beta polypeptide 0.984
DERL1 Der1-like domain family, member 1 0.983
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.967
CANX calnexin 0.957
HSPA1B heat shock 70kDa protein 1B 0.928
HSPA1A heat shock 70kDa protein 1A 0.844
BCL2L1 BCL2-like 1 0.833
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.806
SELS selenoprotein S 0.799
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.757
STON2 stonin 2 0.701
BAG3 BCL2-associated athanogene 3 0.671
PDIA4 protein disulfide isomerase family A, member 4 0.568
GHR growth hormone receptor 0.567
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.520
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.447
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.312
HSPA8 heat shock 70kDa protein 8 0.312
BAG1 BCL2-associated athanogene 0.310
UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 0.291
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.281
ERO1L ERO1-like (S. cerevisiae) 0.267
NSFL1C NSFL1 (p97) cofactor (p47) 0.232
BAX BCL2-associated X protein 0.227
ATF3 activating transcription factor 3 0.211
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.210
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.209
BCL2 B-cell CLL/lymphoma 2 0.202
AMFR autocrine motility factor receptor 0.183
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.153
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.152
HYOU1 hypoxia up-regulated 1 0.139
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.128
GANAB glucosidase, alpha; neutral AB 0.126
HSPB1 heat shock 27kDa protein 1 0.123
C4orf14 chromosome 4 open reading frame 14 0.108
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.106
IARS isoleucyl-tRNA synthetase 0.102
CALR calreticulin 0.100
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.088
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.088
BAG2 BCL2-associated athanogene 2 0.079
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.079
HUWE1 HECT, UBA and WWE domain containing 1 0.074
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.073
NUCB2 nucleobindin 2 0.071
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.070
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.070
FKBP4 FK506 binding protein 4, 59kDa 0.069
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.067
SOS1 son of sevenless homolog 1 (Drosophila) 0.064
ADRBK1 adrenergic, beta, receptor kinase 1 0.063
PTK2 PTK2 protein tyrosine kinase 2 0.061
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.060
RPN2 ribophorin II 0.059
KLHL24 kelch-like 24 (Drosophila) 0.059
UBE4B ubiquitination factor E4B (UFD2 homolog, yeast) 0.053
VDAC1 voltage-dependent anion channel 1 0.051
WDR83 WD repeat domain 83 0.050
PJA2 praja ring finger 2 0.047
HSPH1 heat shock 105kDa/110kDa protein 1 0.044
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.044
PTPRB protein tyrosine phosphatase, receptor type, B 0.044
FAF2 Fas associated factor family member 2 0.044
KIAA0776 KIAA0776 0.041
MKRN1 makorin ring finger protein 1 0.040
JUN jun proto-oncogene 0.040
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.039
CCND3 cyclin D3 0.039
DBP D site of albumin promoter (albumin D-box) binding protein 0.038
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.036
PPHLN1 periphilin 1 0.035
RNF144B ring finger protein 144B 0.034
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.033
HSF1 heat shock transcription factor 1 0.033
UBE2E2 ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) 0.033
DERL2 Der1-like domain family, member 2 0.032
ATXN3 ataxin 3 0.032
ATF2 activating transcription factor 2 0.031
USP46 ubiquitin specific peptidase 46 0.031
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.031
RNF111 ring finger protein 111 0.031
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.030
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.029
RNR2 l-rRNA 0.029
ERN1 endoplasmic reticulum to nucleus signaling 1 0.029
HM13 histocompatibility (minor) 13 0.027
GRB2 growth factor receptor-bound protein 2 0.027
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.025
BAK1 BCL2-antagonist/killer 1 0.025
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.025
SERP1 stress-associated endoplasmic reticulum protein 1 0.025
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.025
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.024
CTTN cortactin 0.024
SEC61G Sec61 gamma subunit 0.024
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Hspa5 heat shock protein 5 0.998
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.997
Creld2 cysteine-rich with EGF-like domains 2 0.962
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.949
Cdk4 cyclin-dependent kinase 4 0.915
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.913
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.815
Pdia3 protein disulfide isomerase associated 3 0.792
Manf mesencephalic astrocyte-derived neurotrophic factor 0.674
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.641
Cdk6 cyclin-dependent kinase 6 0.623
Vcp valosin containing protein 0.584
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.544
Hspa8 heat shock protein 8 0.540
Xbp1 X-box binding protein 1 0.515
H47 histocompatibility 47 0.448
Hsph1 heat shock 105kDa/110kDa protein 1 0.445
Pycard PYD and CARD domain containing 0.431
Ccnd1 cyclin D1 0.405
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.378
Sdf2l1 stromal cell-derived factor 2-like 1 0.324
Ncstn nicastrin 0.306
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.305
Ngly1 N-glycanase 1 0.303
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.294
Hspa1a heat shock protein 1A 0.267
Canx calnexin 0.246
Calr calreticulin 0.217
Surf4 surfeit gene 4 0.214
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.207
Pdia6 protein disulfide isomerase associated 6 0.204
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.200
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.188
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.183
Edem1 ER degradation enhancer, mannosidase alpha-like 1 0.158
Tlr4 toll-like receptor 4 0.153
Magt1 magnesium transporter 1 0.151
Casp1 caspase 1 0.151
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.147
Tmed7 transmembrane emp24 protein transport domain containing 7 0.139
Hspa9 heat shock protein 9 0.131
Trp53 transformation related protein 53 0.126
Bcl2 B-cell leukemia/lymphoma 2 0.118
Il18 interleukin 18 0.115
Hspd1 heat shock protein 1 (chaperonin) 0.112
Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 0.108
Prkcsh protein kinase C substrate 80K-H 0.106
Gbp5 guanylate binding protein 5 0.106
Acsl4 acyl-CoA synthetase long-chain family member 4 0.106
Fas Fas (TNF receptor superfamily member 6) 0.105
Atf6 activating transcription factor 6 0.098
Samm50 sorting and assembly machinery component 50 homolog (S. cerevisiae) 0.090
Dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.087
Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.085
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.084
Mgat2 mannoside acetylglucosaminyltransferase 2 0.081
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.079
Ahi1 Abelson helper integration site 1 0.077
Fndc3a fibronectin type III domain containing 3A 0.077
Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) 0.076
Iqcb1 IQ calmodulin-binding motif containing 1 0.072
Prnp prion protein 0.068
Ifngr1 interferon gamma receptor 1 0.064
P4hb prolyl 4-hydroxylase, beta polypeptide 0.064
Aamp angio-associated migratory protein 0.062
Amfr autocrine motility factor receptor 0.061
Lman2 lectin, mannose-binding 2 0.060
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.057
Arhgap31 Rho GTPase activating protein 31 0.056
Dusp1 dual specificity phosphatase 1 0.055
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 0.055
Il1r1 interleukin 1 receptor, type I 0.053
Myd88 myeloid differentiation primary response gene 88 0.052
Lyz2 lysozyme 2 0.050
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.050
Atf4 activating transcription factor 4 0.048
Aim2 absent in melanoma 2 0.048
1300001I01Rik RIKEN cDNA 1300001I01 gene 0.047
Hyou1 hypoxia up-regulated 1 0.047
Slc30a5 solute carrier family 30 (zinc transporter), member 5 0.046
Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.045
Edem3 ER degradation enhancer, mannosidase alpha-like 3 0.044
Cdk2 cyclin-dependent kinase 2 0.044
Slc35b1 solute carrier family 35, member B1 0.044
Nsfl1c NSFL1 (p97) cofactor (p47) 0.043
Cyld cylindromatosis (turban tumor syndrome) 0.043
Fadd Fas (TNFRSF6)-associated via death domain 0.043
Mcfd2 multiple coagulation factor deficiency 2 0.042
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.041
Lyst lysosomal trafficking regulator 0.041
Plaa phospholipase A2, activating protein 0.040
Syvn1 synovial apoptosis inhibitor 1, synoviolin 0.040
Psen1 presenilin 1 0.040
Uba5 ubiquitin-like modifier activating enzyme 5 0.039
Ssr1 signal sequence receptor, alpha 0.039
Yars tyrosyl-tRNA synthetase 0.039
Ubxn1 UBX domain protein 1 0.039
Serp1 stress-associated endoplasmic reticulum protein 1 0.038
Slc39a7 solute carrier family 39 (zinc transporter), member 7 0.037
Dnajc1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.037
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Pdia6 protein disulfide isomerase family A, member 6 0.499
Hspa5 heat shock protein 5 0.469
Hsph1 heat shock 105/110 protein 1 0.461
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.415
Pdia4 protein disulfide isomerase family A, member 4 0.347
Hsp90b1 heat shock protein 90, beta, member 1 0.327
Pdia3 protein disulfide isomerase family A, member 3 0.264
Creld2 cysteine-rich with EGF-like domains 2 0.166
Manf mesencephalic astrocyte-derived neurotrophic factor 0.142
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.130
Hspd1 heat shock protein 1 (chaperonin) 0.086
Calr calreticulin 0.078
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.069
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.065
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.049
Canx calnexin 0.040
Lman2 lectin, mannose-binding 2 0.040
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.038
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.037
Ubxn4 UBX domain protein 4 0.037
Junb jun B proto-oncogene 0.036
Hspb1 heat shock protein 1 0.034
Sdf2l1 stromal cell-derived factor 2-like 1 0.033
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.033
Rpn2 ribophorin II 0.031
Plscr3 phospholipid scramblase 3 0.029
Hyou1 hypoxia up-regulated 1 0.029
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.028
Ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.028
Snd1 staphylococcal nuclease and tudor domain containing 1 0.027
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.026
Rpn1 ribophorin I 0.026
Ddit3 DNA-damage inducible transcript 3 0.025
Sec23b Sec23 homolog B (S. cerevisiae) 0.024
Ubb ubiquitin B 0.024
RGD1562114 RGD1562114 0.024
Tor1aip2 torsin A interacting protein 2 0.024
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.022
Scamp2 secretory carrier membrane protein 2 0.022
Yars tyrosyl-tRNA synthetase 0.022
Ubc ubiquitin C 0.020
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.020
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.020
Btg1 B-cell translocation gene 1, anti-proliferative 0.019
Chmp1a chromatin modifying protein 1A 0.019
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.018
Stip1 stress-induced phosphoprotein 1 0.018
Nsfl1c NSFL1 (p97) cofactor (p47) 0.018
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.017
Mars methionine-tRNA synthetase 0.017
Erp29 endoplasmic reticulum protein 29 0.017
P4ha1 prolyl 4-hydroxylase, alpha polypeptide I 0.016
Aktip AKT interacting protein 0.016
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.016
Sil1 SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) 0.016
Asmtl acetylserotonin O-methyltransferase-like 0.015
MGC94190 similar to 0610007L01Rik protein 0.015
Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.015
Txndc11 thioredoxin domain containing 11 0.015
Sec24c SEC24 family, member C (S. cerevisiae) 0.015
Atf4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.015
Gars glycyl-tRNA synthetase 0.015
Atf3 activating transcription factor 3 0.015
Hdlbp high density lipoprotein binding protein 0.015
Tmed10 transmembrane emp24-like trafficking protein 10 (yeast) 0.014
Mdfic MyoD family inhibitor domain containing 0.014
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.014
Wsb2 WD repeat and SOCS box-containing 2 0.014
Rrbp1 ribosome binding protein 1 0.014
Hspa8 heat shock protein 8 0.014
P4hb prolyl 4-hydroxylase, beta polypeptide 0.014
Srpr signal recognition particle receptor ('docking protein') 0.014
Mapk3 mitogen activated protein kinase 3 0.014
Sars seryl-tRNA synthetase 0.014
Pdrg1 p53 and DNA damage regulated 1 0.014
Klf4 Kruppel-like factor 4 (gut) 0.013
Lamp2 lysosomal-associated membrane protein 2 0.013
Ggcx gamma-glutamyl carboxylase 0.013
Btd biotinidase 0.013
Gcs1 glucosidase 1 0.013
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.013
Rab5b RAB5B, member RAS oncogene family 0.013
Rdh11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.013
Jun Jun oncogene 0.013
ND1 NADH dehydrogenase subunit 1 0.012
Os9 osteosarcoma amplified 9 0.012
Eif1 eukaryotic translation initiation factor 1 0.012
Crp C-reactive protein, pentraxin-related 0.012
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.012
March8 membrane-associated ring finger (C3HC4) 8 0.012
Tmem66 transmembrane protein 66 0.012
Slc35b1 solute carrier family 35, member B1 0.012
Mospd3 motile sperm domain containing 3 0.012
Scarb2 scavenger receptor class B, member 2 0.012
Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.011
Stk40 serine/threonine kinase 40 0.011
Aph1a anterior pharynx defective 1 homolog A (C. elegans) 0.011
Hdgf2 hepatoma-derived growth factor-related protein 2 0.011
Pelo pelota homolog (Drosophila) 0.011
Xpo6 exportin 6 0.011