The network for 'positive regulation of lymphocyte mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of lymphocyte mediated immunity

Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
zgc:64115 zgc:64115 0.650
nod1 nucleotide-binding oligomerization domain containing 1 0.420
zgc:153921 zgc:153921 0.374
si:dkeyp-110g5.2 si:dkeyp-110g5.2 0.325
LOC557072 caspase recruitment domain-containing protein 11-like 0.283
tlr3 toll-like receptor 3 0.276
LOC100000934 hypothetical protein LOC100000934 0.214
tlr9 toll-like receptor 9 0.206
trim25 tripartite motif-containing 25 0.167
irak4 interleukin-1 receptor-associated kinase 4 0.162
c1qc complement component 1, q subcomponent, C chain 0.160
defbl3 defensin, beta-like 3 0.136
si:ch211-195h23.3 si:ch211-195h23.3 0.135
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.109
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.109
ef1a elongation factor 1-alpha 0.104
c3c complement component c3c 0.102
itln1 intelectin 1 0.101
ppp2r5ea protein phosphatase 2, regulatory subunit B', epsilon isoform a 0.095
foxp3a forkhead box P3a 0.094
tlr21 toll-like receptor 21 0.092
rif1 RAP1 interacting factor homolog (yeast) 0.091
stat6 signal transducer and activator of transcription 6, interleukin-4 induced 0.090
zgc:63831 zgc:63831 0.086
c1qb complement component 1, q subcomponent, B chain 0.083
cd40lg CD40 ligand 0.080
ugt5c2 UDP glucuronosyltransferase 5 family, polypeptide C2 0.077
LOC795096 hypothetical protein LOC795096 0.076
il10 interleukin 10 0.076
zgc:113293 zgc:113293 0.076
illr1 immune-related, lectin-like receptor 1 0.075
nitr5 novel immune-type receptor 5 and immune-type receptor 5-like 0.073
tlr22 toll-like receptor 22 0.073
slc12a10.1 solute carrier family 12 (sodium/potassium/chloride transporters), member 10.1 0.071
nitr13 novel immune-type receptor 13 0.070
il12bb interleukin 12B, b 0.069
fcer1gl Fc receptor, IgE, high affinity I, gamma polypeptide like 0.068
pygb phosphorylase, glycogen; brain 0.067
card9 caspase recruitment domain family, member 9 0.067
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.066
pcsk7 proprotein convertase subtilisin/kexin type 7 0.066
fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.065
tnfrsf18 tumor necrosis factor receptor superfamily, member 18 0.064
illr3 immune-related, lectin-like receptor 3 0.064
cd247l CD247 antigen like 0.063
tbx21 T-box 21 0.063
tufm Tu translation elongation factor, mitochondrial 0.063
zgc:110775 zgc:110775 0.061
zgc:162329 zgc:162329 0.057
LOC794786 interferon-induced protein with tetratricopeptide repeats 1-like 0.057
nitr8 novel immune-type receptor 8 0.055
cd209 CD209 molecule 0.055
wasa Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a 0.055
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.055
itln3 intelectin 3 0.054
lrmp lymphoid-restricted membrane protein 0.053
c1qa complement component 1, q subcomponent, A chain 0.053
psmb9a proteasome (prosome, macropain) subunit, beta type, 9a 0.050
stc1l stanniocalcin 1, like 0.049
grna granulin a 0.049
zgc:64161 zgc:64161 0.048
LOC567504 interferon-induced protein with tetratricopeptide repeats 5-like 0.048
nitr4a novel immune-type receptor 4a 0.048
g6pd glucose-6-phosphate dehydrogenase 0.048
adrb2a adrenergic receptor, beta 2a 0.048
ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1 0.047
ifnphi1 interferon phi 1 0.047
wu:fk76c08 wu:fk76c08 0.047
pth1a parathyroid hormone 1a 0.047
npy7r neuropeptide Y receptor Y7 0.047
nitr12 novel immune-type receptor 12 0.046
zgc:123282 zgc:123282 0.045
nos2a nitric oxide synthase 2a, inducible 0.045
pycard PYD and CARD domain containing 0.045
b2m beta-2-microglobulin 0.045
si:ch211-140f21.1 si:ch211-140f21.1 0.043
prdm9 PR domain containing 9 0.043
gsk3b glycogen synthase kinase 3 beta 0.042
crfb7 cytokine receptor family member b7 0.042
ugt5a2 UDP glucuronosyltransferase 5 family, polypeptide A2 0.041
LOC567441 interferon-induced protein with tetratricopeptide repeats 5-like 0.041
crfa31.2 IL-4RA-like protein 2 0.041
LOC100534776 toll-like receptor 7-like 0.041
slc9a3.2 solute carrier family 9 (sodium/hydrogen exchanger), member 3.2 0.041
ca15a carbonic anhydrase XV a 0.041
phb prohibitin 0.041
LOC793458 peptide Y-like 0.041
dlg2 discs, large (Drosophila) homolog 2 0.041
cd40 CD40 antigen 0.040
tbp TATA box binding protein 0.040
insra insulin receptor a 0.039
vtg6 vitellogenin 6 0.039
LOC100001239 interferon-induced protein with tetratricopeptide repeats 5-like 0.039
card14 caspase recruitment domain family, member 14 0.039
suv39h1b suppressor of variegation 3-9 homolog 1b 0.039
ifng1-2 interferon, gamma 1-2 0.039
angptl1 angiopoietin-like 1 0.038
amh anti-Mullerian hormone 0.038
zgc:101598 zgc:101598 0.037
ptger4b prostaglandin E receptor 4 (subtype EP4) b 0.037
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
B2M beta-2-microglobulin 0.988
HLA-A major histocompatibility complex, class I, A 0.979
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.960
HLA-C major histocompatibility complex, class I, C 0.919
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.846
SLAMF1 signaling lymphocytic activation molecule family member 1 0.841
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.829
SH2D1A SH2 domain containing 1A 0.800
TAPBP TAP binding protein (tapasin) 0.751
IL4R interleukin 4 receptor 0.727
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.704
HLA-B major histocompatibility complex, class I, B 0.685
CCL5 chemokine (C-C motif) ligand 5 0.681
TRAF3 TNF receptor-associated factor 3 0.678
CD84 CD84 molecule 0.639
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.585
CD40 CD40 molecule, TNF receptor superfamily member 5 0.521
CCR5 chemokine (C-C motif) receptor 5 0.521
HLA-G major histocompatibility complex, class I, G 0.517
IL2RB interleukin 2 receptor, beta 0.491
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.337
CCL4 chemokine (C-C motif) ligand 4 0.270
GRAP2 GRB2-related adaptor protein 2 0.268
CXCL9 chemokine (C-X-C motif) ligand 9 0.246
TRAF1 TNF receptor-associated factor 1 0.239
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.205
FASLG Fas ligand (TNF superfamily, member 6) 0.204
ITM2B integral membrane protein 2B 0.199
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.197
TRAF2 TNF receptor-associated factor 2 0.190
BIRC3 baculoviral IAP repeat containing 3 0.181
IFNG interferon, gamma 0.164
IL23A interleukin 23, alpha subunit p19 0.156
INSR insulin receptor 0.148
SYK spleen tyrosine kinase 0.146
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.130
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.128
HLA-E major histocompatibility complex, class I, E 0.123
GBA glucosidase, beta, acid 0.121
CXCL10 chemokine (C-X-C motif) ligand 10 0.121
GZMK granzyme K (granzyme 3; tryptase II) 0.117
CD80 CD80 molecule 0.115
ICAM1 intercellular adhesion molecule 1 0.114
IL2RG interleukin 2 receptor, gamma 0.084
SQSTM1 sequestosome 1 0.078
ENG endoglin 0.076
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.074
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.074
CCL2 chemokine (C-C motif) ligand 2 0.070
CD22 CD22 molecule 0.069
CXCL3 chemokine (C-X-C motif) ligand 3 0.067
CFH complement factor H 0.063
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.061
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.059
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.059
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.058
PRF1 perforin 1 (pore forming protein) 0.055
CXCL11 chemokine (C-X-C motif) ligand 11 0.055
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.054
TP53BP1 tumor protein p53 binding protein 1 0.054
RIPK2 receptor-interacting serine-threonine kinase 2 0.054
PVRL4 poliovirus receptor-related 4 0.053
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.053
TRADD TNFRSF1A-associated via death domain 0.053
CCR7 chemokine (C-C motif) receptor 7 0.053
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.053
CCL8 chemokine (C-C motif) ligand 8 0.051
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.051
CCR1 chemokine (C-C motif) receptor 1 0.051
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.050
CXCR6 chemokine (C-X-C motif) receptor 6 0.050
HLA-F major histocompatibility complex, class I, F 0.050
IRF1 interferon regulatory factor 1 0.050
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.050
NUMBL numb homolog (Drosophila)-like 0.048
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.048
CD8A CD8a molecule 0.048
FAS Fas (TNF receptor superfamily, member 6) 0.048
TRAF5 TNF receptor-associated factor 5 0.047
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.044
CCL7 chemokine (C-C motif) ligand 7 0.044
NCSTN nicastrin 0.044
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.043
GNS glucosamine (N-acetyl)-6-sulfatase 0.043
CCR4 chemokine (C-C motif) receptor 4 0.040
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.038
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.037
CCL19 chemokine (C-C motif) ligand 19 0.036
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.035
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.035
CCL22 chemokine (C-C motif) ligand 22 0.035
IL10RA interleukin 10 receptor, alpha 0.034
IL18RAP interleukin 18 receptor accessory protein 0.034
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.034
GNLY granulysin 0.033
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.033
CD86 CD86 molecule 0.032
NKG7 natural killer cell group 7 sequence 0.032
TNF tumor necrosis factor 0.032
JAK2 Janus kinase 2 0.032
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Mus musculus
Name Description Probability Func Analog Organism
Cd40 CD40 antigen 0.995
Icos inducible T-cell co-stimulator 0.991
Tnf tumor necrosis factor 0.990
Igh immunoglobulin heavy chain complex 0.983
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.942
Cd28 CD28 antigen 0.929
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.918
Fas Fas (TNF receptor superfamily member 6) 0.898
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.886
Il4 interleukin 4 0.879
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.849
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.841
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.836
H2-K1 histocompatibility 2, K1, K region 0.824
Il2 interleukin 2 0.803
H2-D1 histocompatibility 2, D region locus 1 0.794
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.790
B2m beta-2 microglobulin 0.780
Ccr1 chemokine (C-C motif) receptor 1 0.770
Lta lymphotoxin A 0.749
Prf1 perforin 1 (pore forming protein) 0.746
Ccl2 chemokine (C-C motif) ligand 2 0.714
Fasl Fas ligand (TNF superfamily, member 6) 0.701
Clec4d C-type lectin domain family 4, member d 0.699
Slamf1 signaling lymphocytic activation molecule family member 1 0.678
Clec4n C-type lectin domain family 4, member n 0.667
Cd19 CD19 antigen 0.640
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.634
Gzmk granzyme K 0.615
Gzma granzyme A 0.552
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.533
Xcl1 chemokine (C motif) ligand 1 0.515
Il6 interleukin 6 0.505
Ncr1 natural cytotoxicity triggering receptor 1 0.503
Tapbp TAP binding protein 0.499
Foxp3 forkhead box P3 0.488
Pax5 paired box gene 5 0.480
Il2rb interleukin 2 receptor, beta chain 0.461
Il1b interleukin 1 beta 0.437
Ikzf1 IKAROS family zinc finger 1 0.435
Mefv Mediterranean fever 0.418
Itk IL2-inducible T-cell kinase 0.415
Ifng interferon gamma 0.414
Il4ra interleukin 4 receptor, alpha 0.405
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.404
Cd44 CD44 antigen 0.397
H2-Q7 histocompatibility 2, Q region locus 7 0.395
Cxcl9 chemokine (C-X-C motif) ligand 9 0.394
Ccl8 chemokine (C-C motif) ligand 8 0.384
Il12b interleukin 12b 0.371
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.353
Pdcd1 programmed cell death 1 0.344
Socs1 suppressor of cytokine signaling 1 0.339
Il10 interleukin 10 0.332
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.331
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.325
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.324
Clec4e C-type lectin domain family 4, member e 0.299
Il18rap interleukin 18 receptor accessory protein 0.298
Pnp2 purine-nucleoside phosphorylase 2 0.295
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.290
Cd8b1 CD8 antigen, beta chain 1 0.274
Stat5a signal transducer and activator of transcription 5A 0.265
Ciita class II transactivator 0.258
Pdcd1lg2 programmed cell death 1 ligand 2 0.256
Mmp12 matrix metallopeptidase 12 0.254
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.245
Apoe apolipoprotein E 0.242
Stat5b signal transducer and activator of transcription 5B 0.240
Msr1 macrophage scavenger receptor 1 0.236
C3 complement component 3 0.231
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.228
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.221
Ccl9 chemokine (C-C motif) ligand 9 0.221
Tcra T-cell receptor alpha chain 0.221
Irg1 immunoresponsive gene 1 0.217
Batf basic leucine zipper transcription factor, ATF-like 0.215
Cd7 CD7 antigen 0.208
Cd96 CD96 antigen 0.197
Cd5 CD5 antigen 0.195
Gzmb granzyme B 0.187
Ubd ubiquitin D 0.185
Klrc1 killer cell lectin-like receptor subfamily C, member 1 0.184
Traf2 TNF receptor-associated factor 2 0.183
Hcst hematopoietic cell signal transducer 0.182
Lyz2 lysozyme 2 0.181
Ikbkb inhibitor of kappaB kinase beta 0.179
Ccr7 chemokine (C-C motif) receptor 7 0.177
Trem3 triggering receptor expressed on myeloid cells 3 0.177
Ccl7 chemokine (C-C motif) ligand 7 0.168
Aoah acyloxyacyl hydrolase 0.164
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.161
Cxcr5 chemokine (C-X-C motif) receptor 5 0.161
Ccl22 chemokine (C-C motif) ligand 22 0.160
Stat3 signal transducer and activator of transcription 3 0.157
Cd209d CD209d antigen 0.156
Clec7a C-type lectin domain family 7, member a 0.155
Il7 interleukin 7 0.152
Fcgr3 Fc receptor, IgG, low affinity III 0.151
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.150
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.414
RT1-EC2 RT1 class Ib, locus EC2 0.247
Hsph1 heat shock 105/110 protein 1 0.167
Stip1 stress-induced phosphoprotein 1 0.051
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.050
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.043
RT1-CE12 RT1 class I, locus CE12 0.040
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.034
Apol3 apolipoprotein L, 3 0.025
Gbp2 guanylate binding protein 2 0.020
Hspb1 heat shock protein 1 0.018
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.018
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.018
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.017
Casp1 caspase 1 0.017
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.015
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.014
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.013
Gzmb granzyme B 0.012
Cd247 Cd247 molecule 0.012
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.012
Ccl5 chemokine (C-C motif) ligand 5 0.010
Cxcr4 chemokine (C-X-C motif) receptor 4 0.010
Fth1 ferritin, heavy polypeptide 1 0.010