The network for 'regulation of cellular amine metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cellular amine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.

Name Description Probability Func Analog Organism
SPT16 Spt16p 0.195
KOG1 Kog1p 0.138
MET4 Met4p 0.137
CLA4 Cla4p 0.110
MET30 Met30p 0.103
BCK1 Bck1p 0.098
LEO1 Leo1p 0.096
MDM35 Mdm35p 0.088
BDF1 Bdf1p 0.079
RTF1 Rtf1p 0.069
MDH1 Mdh1p 0.064
NGG1 Ngg1p 0.059
STE12 Ste12p 0.056
CKA1 Cka1p 0.055
MCM1 Mcm1p 0.054
NBP2 Nbp2p 0.054
FAR1 Far1p 0.053
PTC1 Ptc1p 0.053
SAP190 Sap190p 0.052
UFO1 Ufo1p 0.050
NOP10 Nop10p 0.047
DIG1 Dig1p 0.047
PSD2 Psd2p 0.046
STE5 Ste5p 0.046
FIS1 Fis1p 0.046
EBP2 Ebp2p 0.046
KEM1 Kem1p 0.045
HIR1 Hir1p 0.042
GDS1 Gds1p 0.042
UPS3 Ups3p 0.042
ARG81 Arg81p 0.042
DNM1 Dnm1p 0.041
KES1 Kes1p 0.041
MET14 Met14p 0.040
SKI8 Ski8p 0.040
IZH4 Izh4p 0.040
TOR1 Tor1p 0.039
GCR2 Gcr2p 0.037
CDC55 Cdc55p 0.037
CAB3 Cab3p 0.037
CLB2 Clb2p 0.037
OYE2 Oye2p 0.036
SPA2 Spa2p 0.035
CDC12 Cdc12p 0.034
MNN9 Mnn9p 0.034
LOC1 Loc1p 0.034
RSC8 Rsc8p 0.034
GIC1 Gic1p 0.034
AVO1 Avo1p 0.034
YML081W hypothetical protein 0.034
FMS1 Fms1p 0.033
YPK1 Ypk1p 0.033
YGL010W hypothetical protein 0.032
RTT109 Rtt109p 0.032
HRT3 Hrt3p 0.032
STR2 Str2p 0.031
ZDS1 Zds1p 0.031
BIT61 Bit61p 0.031
TIF4632 Tif4632p 0.031
TAF8 Taf8p 0.031
CDC24 Cdc24p 0.030
SPT8 Spt8p 0.030
HST3 Hst3p 0.030
GIC2 Gic2p 0.029
NDD1 Ndd1p 0.029
ISW2 Isw2p 0.029
SEC13 Sec13p 0.029
ACC1 Acc1p 0.029
BAS1 Bas1p 0.029
BOI2 Boi2p 0.029
SUM1 Sum1p 0.029
HCR1 Hcr1p 0.029
NMD5 Nmd5p 0.029
ARG80 Arg80p 0.029
CDC34 Cdc34p 0.029
MDV1 Mdv1p 0.028
YCK2 Yck2p 0.028
JLP2 Jlp2p 0.028
CTR9 Ctr9p 0.028
SIN3 Sin3p 0.028
EHT1 Eht1p 0.028
HFA1 Hfa1p 0.027
RAD53 Rad53p 0.027
YHB1 Yhb1p 0.027
TAF10 Taf10p 0.027
FUS3 Fus3p 0.027
YLR422W hypothetical protein 0.027
BUD8 Bud8p 0.027
KIN3 Kin3p 0.027
STE4 Ste4p 0.027
SOK2 Sok2p 0.027
TAF6 Taf6p 0.026
HST1 Hst1p 0.026
DST1 Dst1p 0.026
VID22 Vid22p 0.026
TAF4 Taf4p 0.026
SRD1 Srd1p 0.026
SFG1 Sfg1p 0.026
TEC1 Tec1p 0.026
MSS4 Mss4p 0.026
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
tps-1 Protein TPS-1 0.059
magi-1 Protein MAGI-1 0.047
prp-21 Protein PRP-21 0.047
cam-1 Protein CAM-1 0.047
pdfr-1 Protein PDFR-1 0.046
sma-6 Protein SMA-6 0.045
lin-11 Protein LIN-11 0.043
daf-1 Protein DAF-1 0.043
app-1 Protein APP-1 0.040
C31E10.5 Protein C31E10.5 0.037
lag-1 Protein LAG-1 0.037
C32D5.11 Protein C32D5.11 0.036
mca-1 Protein MCA-1 0.036
CELE_C17E4.6 Protein C17E4.6 0.036
ikb-1 Protein IKB-1 0.036
daf-5 Protein DAF-5 0.036
pat-3 Protein PAT-3 0.035
aak-2 Protein AAK-2 0.035
jmjd-2 Protein JMJD-2 0.035
C14A4.6 Protein C14A4.6 0.035
zoo-1 Protein ZOO-1 0.035
daf-3 Protein DAF-3 0.035
egl-18 Protein EGL-18 0.035
CELE_T26A8.4 Protein T26A8.4 0.035
egl-46 Protein EGL-46 0.034
pde-2 Protein PDE-2 0.034
frm-7 Protein FRM-7 0.034
pes-22 Protein PES-22 0.034
pxf-1 Protein PXF-1 0.034
inx-15 Protein INX-15 0.033
dpy-26 Protein DPY-26 0.033
nhr-69 Protein NHR-69 0.033
mdt-8 Protein MDT-8 0.033
F14B8.6 Protein F14B8.6 0.033
egl-27 Protein EGL-27 0.033
miz-1 Protein MIZ-1 0.032
F21A10.2 Protein F21A10.2 0.032
egl-36 Protein EGL-36 0.032
aqp-4 Protein AQP-4 0.032
cec-1 Protein CEC-1 0.032
dpl-1 Protein DPL-1 0.031
npp-2 Protein NPP-2 0.031
ver-3 Protein VER-3 0.031
ric-3 Protein RIC-3 0.031
hmg-1.2 Protein HMG-1.2 0.031
egl-8 Protein EGL-8 0.031
mel-11 Protein MEL-11 0.031
C52B9.4 Protein C52B9.4 0.031
gei-4 Protein GEI-4 0.031
hlh-1 Protein HLH-1 0.030
B0303.2 Protein B0303.2 0.030
hum-6 Protein HUM-6 0.030
C34D10.2 Protein C34D10.2 0.030
W09D10.1 Protein W09D10.1 0.030
ubxn-1 Protein UBXN-1 0.030
C14H10.2 Protein C14H10.2 0.030
cwn-1 Protein CWN-1 0.029
glo-4 Protein GLO-4 0.029
nra-3 Protein NRA-3 0.029
zfp-1 Protein ZFP-1 0.029
bet-2 Protein BET-2 0.029
F28B3.1 Protein F28B3.1 0.029
sek-1 Protein SEK-1 0.029
tag-232 Protein TAG-232 0.028
T12G3.4 Protein T12G3.4 0.028
atf-6 Protein ATF-6 0.028
nhr-34 Protein NHR-34 0.028
dgk-4 Protein DGK-4 0.028
mat-3 Protein MAT-3 0.028
fhod-1 Protein FHOD-1 0.028
trim-9 Protein TRIM-9 0.028
R11A8.7 Protein R11A8.7 0.028
clh-5 Protein CLH-5 0.028
pad-1 Protein PAD-1 0.028
goa-1 Protein GOA-1 0.028
T28B4.1 Protein T28B4.1 0.028
daf-2 Protein DAF-2 0.028
Y4C6B.1 Protein Y4C6B.1 0.027
patr-1 Protein PATR-1 0.027
dnj-5 Protein DNJ-5 0.027
rict-1 Protein RICT-1 0.027
T23F11.1 Protein T23F11.1 0.027
unc-79 Protein UNC-79 0.027
unc-54 Protein UNC-54 0.027
ags-3 Protein AGS-3 0.027
nrde-3 Protein NRDE-3 0.027
gei-17 Protein GEI-17 0.027
hlh-30 Protein HLH-30 0.027
mig-38 Protein MIG-38 0.027
sea-2 Protein SEA-2 0.026
vps-11 Protein VPS-11 0.026
egl-26 Protein EGL-26 0.026
egl-5 Protein EGL-5 0.026
CELE_T04H1.2 Protein T04H1.2 0.026
lsy-12 Protein LSY-12 0.026
pha-4 Protein PHA-4 0.026
fib-1 Protein FIB-1 0.026
hcp-2 Protein HCP-2 0.026
chat-1 Protein CHAT-1 0.026
spd-1 Protein SPD-1 0.026
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.520
tal1 T-cell acute lymphocytic leukemia 1 0.429
zgc:64051 zgc:64051 0.407
aplnra apelin receptor a 0.404
fn1 fibronectin 1 0.378
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.374
fn1b fibronectin 1b 0.346
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.332
mpx myeloid-specific peroxidase 0.320
wnt4a wingless-type MMTV integration site family, member 4a 0.295
tert telomerase reverse transcriptase 0.265
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.250
bnc2 basonuclin 2 0.237
ptgs1 prostaglandin-endoperoxide synthase 1 0.228
card9 caspase recruitment domain family, member 9 0.224
dusp6 dual specificity phosphatase 6 0.218
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.217
ghra growth hormone receptor a 0.215
smad1 MAD homolog 1 (Drosophila) 0.213
angptl1 angiopoietin-like 1 0.204
mfn2 mitofusin 2 0.202
itgb1a integrin, beta 1a 0.199
angptl2 angiopoietin-like 2 0.199
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.198
flt4 fms-related tyrosine kinase 4 0.198
dag1 dystroglycan 1 0.197
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.196
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.196
ptena phosphatase and tensin homolog A 0.189
mapk6 mitogen-activated protein kinase 6 0.186
st8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.186
cnr1 cannabinoid receptor 1 0.182
smad9 MAD homolog 9 (Drosophila) 0.179
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.179
bmp2a bone morphogenetic protein 2a 0.177
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.177
ube2i2 ubiquitin-conjugating enzyme E2I2 0.177
lpp LIM domain containing preferred translocation partner in lipoma 0.176
mapk3 mitogen-activated protein kinase 3 0.172
tlr3 toll-like receptor 3 0.170
irf9 interferon regulatory factor 9 0.168
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.166
hgfb hepatocyte growth factor b 0.165
sc:d812 sc:d812 0.163
usp1 ubiquitin specific protease 1 0.161
cdx4 caudal type homeo box transcription factor 4 0.161
mmp9 matrix metalloproteinase 9 0.160
fzd7a frizzled homolog 7a 0.159
cmyb transcription factor cmyb 0.159
si:ch211-173o4.2 si:ch211-173o4.2 0.158
fgfr2 fibroblast growth factor receptor 2 0.156
wu:fb63c04 wu:fb63c04 0.148
mbnl2 muscleblind-like 2 (Drosophila) 0.146
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.146
nod1 nucleotide-binding oligomerization domain containing 1 0.146
tp53bp2 tumor protein p53 binding protein, 2 0.145
ocrl oculocerebrorenal syndrome of Lowe 0.144
angptl7 angiopoietin-like 7 0.143
fbln4 fibulin 4 0.140
ascl1a achaete-scute complex-like 1a (Drosophila) 0.140
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.139
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.134
fgfr4 fibroblast growth factor receptor 4 0.130
LOC557072 caspase recruitment domain-containing protein 11-like 0.130
cbx1a chromobox homolog 1a (HP1 beta homolog Drosophila) 0.130
stat3 signal transduction and activation of transcription 3 0.130
her1 hairy-related 1 0.130
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.130
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.129
col7a1l collagen type VII alpha 1-like 0.129
sdc2 syndecan 2 0.127
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.127
hs6st1b heparan sulfate 6-O-sulfotransferase 1b 0.127
ntn2 netrin 2 0.125
igf1ra insulin-like growth factor 1a receptor 0.124
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.124
kbp kif1-binding protein 0.123
rhoub ras homolog gene family, member Ub 0.122
hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.122
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.121
lhcgr luteinizing hormone/choriogonadotropin receptor 0.118
socs1 suppressor of cytokine signaling 1 0.117
her15.1 hairy and enhancer of split-related 15.1 0.117
sh3gl1b SH3-domain GRB2-like 1b 0.117
ghrb growth hormone receptor b 0.115
csf1ra colony stimulating factor 1 receptor, a 0.115
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.114
spna2 spectrin alpha 2 0.114
slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 0.114
fas Fas (TNF receptor superfamily, member 6) 0.113
crx cone-rod homeobox 0.113
cse1l chromosome segregation 1-like (S. cerevisiae) 0.113
LOC100332193 growth hormone secretagogue receptor type 1-like 0.113
lcp1 lymphocyte cytosolic plastin 1 0.112
appa amyloid beta (A4) precursor protein a 0.112
ighz immunoglobulin heavy constant zeta 0.111
sb:cb429 sb:cb429 0.111
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.110
helt hey-like transcription factor 0.110
tbp TATA box binding protein 0.108
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Smox Smad on X 0.744
Mad Mothers against dpp 0.710
Egfr Epidermal growth factor receptor 0.704
shn schnurri 0.647
HLHm7 E(spl) region transcript m7 0.575
E(spl) Enhancer of split 0.551
numb CG3779 gene product from transcript CG3779-RB 0.522
HLHmbeta E(spl) region transcript mbeta 0.488
mbc myoblast city 0.483
Adf1 Adh transcription factor 1 0.470
HLHmdelta E(spl) region transcript mdelta 0.467
rl rolled 0.461
emc extra macrochaetae 0.460
Ras85D Ras oncogene at 85D 0.446
ush u-shaped 0.426
drpr draper 0.369
fog folded gastrulation 0.362
spas spastin 0.360
HLHmgamma E(spl) region transcript mgamma 0.350
Su(var)205 Suppressor of variegation 205 0.346
ash2 absent, small, or homeotic discs 2 0.321
HLHm5 E(spl) region transcript m5 0.305
bsk basket 0.277
mew multiple edematous wings 0.273
htl heartless 0.269
Tom Twin of m4 0.251
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.251
Mer Merlin 0.234
aop anterior open 0.229
dm diminutive 0.224
O-fut1 O-fucosyltransferase 1 0.224
ds dachsous 0.220
Rel Relish 0.215
CtBP C-terminal Binding Protein 0.210
par-1 CG8201 gene product from transcript CG8201-RA 0.210
Atg1 Autophagy-specific gene 1 0.204
Tm1 Tropomyosin 1 0.203
Git CG16728 gene product from transcript CG16728-RA 0.203
Pink1 PTEN-induced putative kinase 1 0.201
hppy happyhour 0.199
Dcp-1 Death caspase-1 0.196
Pten CG5671 gene product from transcript CG5671-RB 0.189
CG12424 CG12424 gene product from transcript CG12424-RC 0.187
ci cubitus interruptus 0.187
CG1021 CG1021 gene product from transcript CG1021-RE 0.186
Sara Smad anchor for receptor activation 0.184
HLHm3 E(spl) region transcript m3 0.176
zfh1 Zn finger homeodomain 1 0.176
malpha E(spl) region transcript malpha 0.175
yata CG1973 gene product from transcript CG1973-RA 0.172
Krn Keren 0.169
usp ultraspiracle 0.167
sog short gastrulation 0.166
Dref DNA replication-related element factor 0.165
Sos Son of sevenless 0.165
Sulf1 Sulfated 0.164
scb scab 0.163
ninaE neither inactivation nor afterpotential E 0.163
grk gurken 0.162
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.161
woc without children 0.160
CG5669 CG5669 gene product from transcript CG5669-RA 0.156
srp serpent 0.156
Cul-4 Cullin-4 0.155
MRG15 CG6363 gene product from transcript CG6363-RA 0.154
capt capulet 0.153
Dad Daughters against dpp 0.153
Galpha49B G protein alpha49B 0.152
Hcf Host cell factor 0.149
SoxN SoxNeuro 0.149
lin19 lin-19-like 0.148
ari-2 ariadne 2 0.146
wb wing blister 0.144
Appl beta amyloid protein precursor-like 0.143
Ras64B Ras oncogene at 64B 0.143
puc puckered 0.140
Tsc1 CG6147 gene product from transcript CG6147-RA 0.139
inaD inactivation no afterpotential D 0.138
stai stathmin 0.136
krz kurtz 0.136
bs blistered 0.136
rg rugose 0.135
CG9247 CG9247 gene product from transcript CG9247-RA 0.133
ru roughoid 0.132
elav embryonic lethal abnormal vision 0.130
CG2116 CG2116 gene product from transcript CG2116-RA 0.128
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.127
Rac2 CG8556 gene product from transcript CG8556-RA 0.126
Src42A Src oncogene at 42A 0.125
Sir2 CG5216 gene product from transcript CG5216-RA 0.125
Abl Abl tyrosine kinase 0.124
Rala Ras-related protein 0.119
gbb glass bottom boat 0.118
yki yorkie 0.118
B-H1 BarH1 0.117
Uba1 Ubiquitin activating enzyme 1 0.117
argos CG4531 gene product from transcript CG4531-RA 0.115
l(3)05822 lethal (3) 05822 0.114
m2 E(spl) region transcript m2 0.114
RASSF8 CG5053 gene product from transcript CG5053-RA 0.112
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 1.000
APP amyloid beta (A4) precursor protein 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.999
SYK spleen tyrosine kinase 0.999
MET met proto-oncogene (hepatocyte growth factor receptor) 0.999
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.999
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.998
FGFR2 fibroblast growth factor receptor 2 0.998
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.998
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.997
SH3KBP1 SH3-domain kinase binding protein 1 0.997
SOCS3 suppressor of cytokine signaling 3 0.997
BCAR1 breast cancer anti-estrogen resistance 1 0.996
SMAD3 SMAD family member 3 0.995
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.994
BCL2 B-cell CLL/lymphoma 2 0.994
BTK Bruton agammaglobulinemia tyrosine kinase 0.994
CBX5 chromobox homolog 5 0.994
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.993
PTPRC protein tyrosine phosphatase, receptor type, C 0.993
SOCS1 suppressor of cytokine signaling 1 0.992
TP53 tumor protein p53 0.992
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.992
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.990
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.990
PLCG1 phospholipase C, gamma 1 0.989
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.988
HDAC1 histone deacetylase 1 0.988
FGFR1 fibroblast growth factor receptor 1 0.988
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.988
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.988
FGF1 fibroblast growth factor 1 (acidic) 0.988
SMAD7 SMAD family member 7 0.986
PTK2 PTK2 protein tyrosine kinase 2 0.986
TEK TEK tyrosine kinase, endothelial 0.986
PRKCA protein kinase C, alpha 0.983
VAV1 vav 1 guanine nucleotide exchange factor 0.983
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.981
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.980
VEGFA vascular endothelial growth factor A 0.978
ESR1 estrogen receptor 1 0.978
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.978
NCK1 NCK adaptor protein 1 0.978
AXL AXL receptor tyrosine kinase 0.977
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.976
FHL2 four and a half LIM domains 2 0.975
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.974
SFN stratifin 0.972
BIRC3 baculoviral IAP repeat containing 3 0.970
ENG endoglin 0.970
PAX3 paired box 3 0.968
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.967
GAB1 GRB2-associated binding protein 1 0.965
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.964
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.964
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.961
LAT linker for activation of T cells 0.960
BCL2L1 BCL2-like 1 0.960
STK11 serine/threonine kinase 11 0.958
GHR growth hormone receptor 0.957
CREBBP CREB binding protein 0.955
ICAM1 intercellular adhesion molecule 1 0.953
GRB2 growth factor receptor-bound protein 2 0.950
TRADD TNFRSF1A-associated via death domain 0.948
CCR5 chemokine (C-C motif) receptor 5 0.946
TGFB1 transforming growth factor, beta 1 0.946
CAV1 caveolin 1, caveolae protein, 22kDa 0.944
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.937
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.937
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.935
SPRR2A small proline-rich protein 2A 0.933
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.933
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.928
ARRB1 arrestin, beta 1 0.925
VCAM1 vascular cell adhesion molecule 1 0.917
DLG1 discs, large homolog 1 (Drosophila) 0.915
LRP6 low density lipoprotein receptor-related protein 6 0.914
YAP1 Yes-associated protein 1 0.911
WIPF1 WAS/WASL interacting protein family, member 1 0.910
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.907
EPHA2 EPH receptor A2 0.905
MED28 mediator complex subunit 28 0.904
MPDZ multiple PDZ domain protein 0.901
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.901
IL6 interleukin 6 (interferon, beta 2) 0.900
GH1 growth hormone 1 0.900
MAPT microtubule-associated protein tau 0.898
RBBP4 retinoblastoma binding protein 4 0.895
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.887
RBBP5 retinoblastoma binding protein 5 0.887
NRIP1 nuclear receptor interacting protein 1 0.886
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.884
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Grb2 growth factor receptor bound protein 2 1.000
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Tgfb1 transforming growth factor, beta 1 0.999
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.998
Csf1 colony stimulating factor 1 (macrophage) 0.997
Gsk3b glycogen synthase kinase 3 beta 0.996
Cbl Casitas B-lineage lymphoma 0.995
Ephb2 Eph receptor B2 0.994
Inpp5d inositol polyphosphate-5-phosphatase D 0.994
Neurod1 neurogenic differentiation 1 0.991
Emx1 empty spiracles homolog 1 (Drosophila) 0.991
Fyn Fyn proto-oncogene 0.991
Lepr leptin receptor 0.989
Apoe apolipoprotein E 0.988
Pax8 paired box gene 8 0.987
Rag1 recombination activating gene 1 0.986
Notch1 Notch gene homolog 1 (Drosophila) 0.986
Plcg1 phospholipase C, gamma 1 0.985
Nos3 nitric oxide synthase 3, endothelial cell 0.985
Stat3 signal transducer and activator of transcription 3 0.983
Bdnf brain derived neurotrophic factor 0.983
Tnf tumor necrosis factor 0.981
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.979
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.978
Axin1 axin 1 0.978
Nos2 nitric oxide synthase 2, inducible 0.975
Mmp9 matrix metallopeptidase 9 0.973
Slamf1 signaling lymphocytic activation molecule family member 1 0.972
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.971
Gata5 GATA binding protein 5 0.971
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.969
Rictor RPTOR independent companion of MTOR, complex 2 0.967
Kit kit oncogene 0.965
Bcl2 B-cell leukemia/lymphoma 2 0.960
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.959
Tlr4 toll-like receptor 4 0.956
Lep leptin 0.956
Pparg peroxisome proliferator activated receptor gamma 0.956
Cd44 CD44 antigen 0.956
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.954
Rxra retinoid X receptor alpha 0.953
Foxc2 forkhead box C2 0.953
Fbn1 fibrillin 1 0.953
Vasp vasodilator-stimulated phosphoprotein 0.951
Bdkrb2 bradykinin receptor, beta 2 0.950
Cav1 caveolin 1, caveolae protein 0.948
Dab1 disabled homolog 1 (Drosophila) 0.941
Vegfa vascular endothelial growth factor A 0.937
Jak2 Janus kinase 2 0.937
Ntf3 neurotrophin 3 0.933
Smad4 MAD homolog 4 (Drosophila) 0.933
Kitl kit ligand 0.928
Dok1 docking protein 1 0.927
Psen1 presenilin 1 0.925
Stat6 signal transducer and activator of transcription 6 0.925
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.924
Rarg retinoic acid receptor, gamma 0.924
Pax6 paired box gene 6 0.923
Col1a1 collagen, type I, alpha 1 0.921
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.920
Prrx1 paired related homeobox 1 0.920
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.917
Smad1 MAD homolog 1 (Drosophila) 0.916
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.911
Esr1 estrogen receptor 1 (alpha) 0.911
Prox1 prospero-related homeobox 1 0.910
Sox10 SRY-box containing gene 10 0.910
Gata6 GATA binding protein 6 0.909
Ret ret proto-oncogene 0.909
Cd28 CD28 antigen 0.908
Ptk2 PTK2 protein tyrosine kinase 2 0.906
Foxn1 forkhead box N1 0.904
Insr insulin receptor 0.903
Ifngr1 interferon gamma receptor 1 0.902
Tbx3 T-box 3 0.900
Nos1 nitric oxide synthase 1, neuronal 0.899
Lhx1 LIM homeobox protein 1 0.898
Egfr epidermal growth factor receptor 0.896
Trp53 transformation related protein 53 0.896
Il10 interleukin 10 0.892
Src Rous sarcoma oncogene 0.890
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.889
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.888
Hand2 heart and neural crest derivatives expressed transcript 2 0.886
Klf4 Kruppel-like factor 4 (gut) 0.885
Prf1 perforin 1 (pore forming protein) 0.884
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.881
Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like 0.879
Kdr kinase insert domain protein receptor 0.877
Adam17 a disintegrin and metallopeptidase domain 17 0.875
Socs1 suppressor of cytokine signaling 1 0.875
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.874
Plxnd1 plexin D1 0.874
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.873
Efna5 ephrin A5 0.872
Emx2 empty spiracles homolog 2 (Drosophila) 0.872
Kl klotho 0.871
Vdr vitamin D receptor 0.871
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.336
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.300
Hck hemopoietic cell kinase 0.269
Slfn2 schlafen 2 0.247
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.238
Prkcd protein kinase C, delta 0.229
Adam17 ADAM metallopeptidase domain 17 0.221
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.209
Fgfr2 fibroblast growth factor receptor 2 0.207
Jak2 Janus kinase 2 0.206
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.204
Rin1 Ras and Rab interactor 1 0.184
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.176
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.173
Reg3g regenerating islet-derived 3 gamma 0.169
Cd4 Cd4 molecule 0.167
Flt1 FMS-related tyrosine kinase 1 0.161
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.152
Casp2 caspase 2 0.150
Gfra2 GDNF family receptor alpha 2 0.147
Grm5 glutamate receptor, metabotropic 5 0.147
Stat3 signal transducer and activator of transcription 3 0.146
Jak1 Janus kinase 1 0.146
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.144
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.142
Pitx3 paired-like homeodomain 3 0.139
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.137
Agtr1a angiotensin II receptor, type 1a 0.136
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.135
Itm2b integral membrane protein 2B 0.135
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.134
Nfib nuclear factor I/B 0.132
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.131
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.128
Grifin galectin-related inter-fiber protein 0.128
Rab1b RAB1B, member RAS oncogene family 0.128
Pcna proliferating cell nuclear antigen 0.127
Pld4 phospholipase D family, member 4 0.127
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.127
Sgk1 serum/glucocorticoid regulated kinase 1 0.126
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.126
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.124
Fgf7 fibroblast growth factor 7 0.124
Csf1 colony stimulating factor 1 (macrophage) 0.123
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.123
Tulp1 tubby like protein 1 0.122
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.121
Il4ra interleukin 4 receptor, alpha 0.121
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.121
Glp1r glucagon-like peptide 1 receptor 0.121
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.120
Vegfa vascular endothelial growth factor A 0.120
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.120
Nrxn1 neurexin 1 0.117
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.116
Acacb acetyl-Coenzyme A carboxylase beta 0.115
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.115
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.114
Notch3 Notch homolog 3 (Drosophila) 0.114
Creb1 cAMP responsive element binding protein 1 0.113
Gzmk granzyme K 0.112
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.111
Acrv1 acrosomal vesicle protein 1 0.110
Prss1 protease, serine, 1 (trypsin 1) 0.109
Nrg1 neuregulin 1 0.109
Vegp2 von Ebners gland protein 2 0.109
Hcrtr2 hypocretin (orexin) receptor 2 0.107
Myo1b myosin Ib 0.107
Vip vasoactive intestinal peptide 0.106
Litaf lipopolysaccharide-induced TNF factor 0.106
Kl Klotho 0.106
Shc1 SHC (Src homology 2 domain containing) transforming protein 1 0.105
RT1-M5 RT1 class Ib, locus M5 0.105
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.104
Begain brain-enriched guanylate kinase-associated 0.103
Mmp10 matrix metallopeptidase 10 0.103
Hras Harvey rat sarcoma virus oncogene 0.103
Hist1h1a histone cluster 1, H1a 0.102
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.102
St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.102
Anxa2 annexin A2 0.101
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.101
Bcan brevican 0.101
Crip2 cysteine-rich protein 2 0.101
Rara retinoic acid receptor, alpha 0.100
Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.100
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.100
Pomp proteasome maturation protein 0.100
Rxra retinoid X receptor alpha 0.099
Cxcr4 chemokine (C-X-C motif) receptor 4 0.099
Ckmt1 creatine kinase, mitochondrial 1 0.099
Gnrhr gonadotropin releasing hormone receptor 0.098
Agxt2 alanine-glyoxylate aminotransferase 2 0.098
Thbd thrombomodulin 0.097
Gip gastric inhibitory polypeptide 0.096
Grp gastrin releasing peptide 0.096
Gzmf granzyme F 0.096
LOC24906 RoBo-1 0.096
Gata6 GATA binding protein 6 0.096
Cntn3 contactin 3 (plasmacytoma associated) 0.096