The network for 'reactive oxygen species metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reactive oxygen species metabolic process

The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CUP1-1 Cup1-1p 0.276
TRX2 Trx2p 0.242
AHP1 Ahp1p 0.208
CAK1 Cak1p 0.155
CUP1-2 Cup1-2p 0.126
SOD1 Sod1p 0.104
TDH2 Tdh2p 0.095
HMX1 Hmx1p 0.084
HOP1 Hop1p 0.075
TSA2 Tsa2p 0.050
ENO1 Eno1p 0.047
TDH1 Tdh1p 0.044
RAD51 Rad51p 0.043
COQ4 Coq4p 0.038
COT1 Cot1p 0.038
YPL014W hypothetical protein 0.038
CTT1 Ctt1p 0.037
TPI1 Tpi1p 0.036
NGL2 Ngl2p 0.036
LAT1 Lat1p 0.034
CTA1 Cta1p 0.032
GPM1 Gpm1p 0.031
MET5 Met5p 0.031
YML053C hypothetical protein 0.030
ACH1 Ach1p 0.029
CWP2 Cwp2p 0.028
TSA1 Tsa1p 0.028
CCW12 Ccw12p 0.028
CRS5 Crs5p 0.027
ERR3 Err3p 0.026
TOR1 Tor1p 0.026
YCF1 Ycf1p 0.026
SLA2 Sla2p 0.024
TDH3 Tdh3p 0.024
DRE2 Dre2p 0.024
SFC1 Sfc1p 0.023
FMP48 Fmp48p 0.023
CYM1 Cym1p 0.022
SRX1 Srx1p 0.022
MGA2 Mga2p 0.022
YGP1 Ygp1p 0.021
TOK1 Tok1p 0.021
PCH2 Pch2p 0.020
PCL5 Pcl5p 0.020
PGK1 Pgk1p 0.019
YNL134C hypothetical protein 0.019
PIM1 Pim1p 0.019
CCS1 Ccs1p 0.019
NNK1 Nnk1p 0.018
MDH3 Mdh3p 0.018
YHB1 Yhb1p 0.018
MET3 Met3p 0.018
SRD1 Srd1p 0.018
YLR162W hypothetical protein 0.017
FMP52 Fmp52p 0.017
YLR264C-A hypothetical protein 0.017
GVP36 Gvp36p 0.017
ZEO1 Zeo1p 0.017
YIG1 Yig1p 0.017
TKL2 Tkl2p 0.017
TGL4 Tgl4p 0.017
PUT2 Put2p 0.017
CUE4 Cue4p 0.017
THG1 Thg1p 0.016
STT4 Stt4p 0.016
LEU2 Leu2p 0.016
YIL151C hypothetical protein 0.016
QCR7 Qcr7p 0.016
CAR1 Car1p 0.016
NHA1 Nha1p 0.016
REE1 Ree1p 0.016
KOG1 Kog1p 0.016
TCO89 Tco89p 0.016
RIM4 Rim4p 0.016
CAM1 Cam1p 0.015
YOL038C-A hypothetical protein 0.015
SPL2 Spl2p 0.015
SAP185 Sap185p 0.015
BNA6 Bna6p 0.015
NEO1 Neo1p 0.015
MER1 Mer1p 0.015
MET17 Met17p 0.015
PDI1 Pdi1p 0.015
ERT1 Ert1p 0.015
YOR302W hypothetical protein 0.014
SAM3 Sam3p 0.014
YCR102C hypothetical protein 0.014
ARG8 Arg8p 0.014
TRR2 Trr2p 0.014
TIP1 Tip1p 0.014
ICL1 Icl1p 0.014
ALD6 Ald6p 0.014
GCY1 Gcy1p 0.014
ARP10 Arp10p 0.014
HOR7 Hor7p 0.014
GYL1 Gyl1p 0.014
YDL124W hypothetical protein 0.013
HUR1 Hur1p 0.013
HSC82 Hsc82p 0.013
GRE2 Gre2p 0.013
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
sh3gl1b SH3-domain GRB2-like 1b 0.416
fabp11a fatty acid binding protein 11a 0.387
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.343
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.307
sox9b SRY-box containing gene 9b 0.285
sod2 superoxide dismutase 2, mitochondrial 0.269
ndufa9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 0.269
pparg peroxisome proliferator activated receptor gamma 0.252
gstp1 glutathione S-transferase pi 0.252
ripk2 receptor-interacting serine-threonine kinase 2 0.237
aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.229
myog myogenin 0.221
tgfb1a transforming growth factor, beta 1a 0.214
stc1l stanniocalcin 1, like 0.209
il8 interleukin 8 0.170
xylt1 xylosyltransferase 1 0.168
zbtb4 zinc finger and BTB domain containing 4 0.160
zgc:64114 zgc:64114 0.153
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.144
furinb furin (paired basic amino acid cleaving enzyme) b 0.140
LOC799612 prolactin 2 0.137
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.127
vdra vitamin D receptor a 0.125
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.123
ptch2 patched 2 0.122
tlr3 toll-like receptor 3 0.121
eif4a1b eukaryotic translation initiation factor 4A, isoform 1B 0.119
mmp13a matrix metalloproteinase 13a 0.118
zgc:64051 zgc:64051 0.117
smyhc1l slow myosin heavy chain 1, like 0.115
ivd isovaleryl Coenzyme A dehydrogenase 0.112
tpm3 tropomyosin 3 0.111
lrrc15 leucine rich repeat containing 15 0.111
uqcrc1 ubiquinol-cytochrome c reductase core protein I 0.109
prdx2 peroxiredoxin 2 0.109
epas1b endothelial PAS domain protein 1b 0.108
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.107
fgf3 fibroblast growth factor 3 0.107
zgc:112986 zgc:112986 0.099
epor erythropoietin receptor 0.099
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.097
cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 0.093
tnnt3a troponin T3a, skeletal, fast 0.093
zgc:111961 zgc:111961 0.092
igfbp1a insulin-like growth factor binding protein 1a 0.092
uqcrc2b ubiquinol-cytochrome c reductase core protein IIb 0.092
sod1 superoxide dismutase 1, soluble 0.091
atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.091
junb jun B proto-oncogene 0.090
mmp9 matrix metalloproteinase 9 0.090
duox dual oxidase 0.089
tbx1 T-box 1 0.089
igf1 insulin-like growth factor 1 0.088
ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.087
zfp36l1a zinc finger protein 36, C3H type-like 1a 0.086
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.085
hcrt hypocretin (orexin) neuropeptide precursor 0.084
acta1a actin, alpha 1a, skeletal muscle 0.083
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.082
si:dkey-27i16.2 si:dkey-27i16.2 0.081
wnt10a wingless-type MMTV integration site family, member 10a 0.081
esd esterase D/formylglutathione hydrolase 0.078
igf1rb insulin-like growth factor 1b receptor 0.078
grid2 glutamate receptor, ionotropic, delta 2 0.075
ahr2 aryl hydrocarbon receptor 2 0.074
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.074
ahcy S-adenosylhomocysteine hydrolase 0.074
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.074
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.073
hspa5 heat shock protein 5 0.072
eng1a engrailed 1a 0.071
zgc:64133 zgc:64133 0.069
cmyb transcription factor cmyb 0.069
caspa caspase a 0.069
tnnc2 troponin C type 2 (fast) 0.069
idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.066
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.065
acad11 acyl-Coenzyme A dehydrogenase family, member 11 0.064
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.064
tpma alpha-tropomyosin 0.063
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.063
mecp2 methyl CpG binding protein 2 0.063
met met proto-oncogene (hepatocyte growth factor receptor) 0.063
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.062
sgk1 serum/glucocorticoid regulated kinase 1 0.062
nme2b.1 non-metastatic cells 2b.1, protein (NM23B) expressed in 0.062
hspb8 heat shock protein, alpha-crystallin-related, b8 0.062
fech ferrochelatase 0.062
lef1 lymphocyte enhancer binding factor 1 0.061
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.061
zgc:73345 zgc:73345 0.061
foxd3 forkhead box D3 0.060
ctgf connective tissue growth factor 0.059
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.059
pgm1 phosphoglucomutase 1 0.058
spns2 spinster homolog 2 (Drosophila) 0.058
krcp kelch repeat-containing protein 0.058
esr1 estrogen receptor 1 0.057
chn1 chimerin (chimaerin) 1 0.057
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.057
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pvr PDGF- and VEGF-receptor related 0.767
Akt1 CG4006 gene product from transcript CG4006-RA 0.522
S6k RPS6-p70-protein kinase 0.498
Atg1 Autophagy-specific gene 1 0.283
Pten CG5671 gene product from transcript CG5671-RB 0.244
Pink1 PTEN-induced putative kinase 1 0.189
Jra Jun-related antigen 0.170
Dcr-2 Dicer-2 0.163
Trx-2 thioredoxin-2 0.162
scb scab 0.159
CG6543 CG6543 gene product from transcript CG6543-RA 0.149
SdhB Succinate dehydrogenase B 0.149
Pk61C Protein kinase 61C 0.145
CaMKII Calcium/calmodulin-dependent protein kinase II 0.136
vkg viking 0.130
Hsp22 Heat shock protein 22 0.129
VhaAC39 Vacuolar H[+]-ATPase C39 subunit 0.128
Sod Superoxide dismutase 0.123
Hsp68 Heat shock protein 68 0.120
CG6429 CG6429 gene product from transcript CG6429-RA 0.119
Tbh Tyramine beta hydroxylase 0.113
Act57B Actin 57B 0.105
Fatp Fatty acid (long chain) transport protein 0.103
dj-1beta CG1349 gene product from transcript CG1349-RA 0.093
ird5 immune response deficient 5 0.092
CG13253 CG13253 gene product from transcript CG13253-RB 0.087
CG6783 CG6783 gene product from transcript CG6783-RC 0.084
kay kayak 0.079
Sod2 Superoxide dismutase 2 (Mn) 0.077
p38b CG7393 gene product from transcript CG7393-RA 0.074
drk downstream of receptor kinase 0.073
CG3004 CG3004 gene product from transcript CG3004-RA 0.073
Mhc Myosin heavy chain 0.072
Rel Relish 0.072
Actn alpha actinin 0.070
Spargel CG9809 gene product from transcript CG9809-RB 0.069
InR Insulin-like receptor 0.068
dm diminutive 0.068
chrb charybde 0.068
babo baboon 0.066
CycJ Cyclin J 0.065
Jafrac1 thioredoxin peroxidase 1 0.065
Lectin-galC1 Galactose-specific C-type lectin 0.061
Trim9 CG31721 gene product from transcript CG31721-RB 0.061
Thor CG8846 gene product from transcript CG8846-RA 0.060
Hsp26 Heat shock protein 26 0.058
Prx2540-1 Peroxiredoxin 2540 0.058
nej nejire 0.056
fln flightin 0.056
CG15199 CG15199 gene product from transcript CG15199-RA 0.053
jeb jelly belly 0.051
ninaA neither inactivation nor afterpotential A 0.048
Trxr-1 Thioredoxin reductase-1 0.046
scyl scylla 0.045
chico CG5686 gene product from transcript CG5686-RB 0.044
Gycalpha99B Guanylyl cyclase alpha-subunit at 99B 0.044
CG2852 CG2852 gene product from transcript CG2852-RA 0.044
cln3 CG5582 gene product from transcript CG5582-RA 0.043
CG14290 CG14290 gene product from transcript CG14290-RB 0.043
Rab7 Rab-protein 7 0.042
klg klingon 0.041
nwk nervous wreck 0.041
park parkin 0.040
CG5794 CG5794 gene product from transcript CG5794-RB 0.040
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.039
Fmr1 CG6203 gene product from transcript CG6203-RC 0.039
LamC Lamin C 0.037
CG10219 CG10219 gene product from transcript CG10219-RA 0.037
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.037
CG30410 CG30410 gene product from transcript CG30410-RB 0.037
repo reversed polarity 0.037
LanA Laminin A 0.037
Ras85D Ras oncogene at 85D 0.036
sls sallimus 0.036
Act88F Actin 88F 0.036
Cat Catalase 0.036
dos daughter of sevenless 0.034
boss bride of sevenless 0.034
Cg25C Collagen type IV 0.034
Mpk2 CG5475 gene product from transcript CG5475-RB 0.033
Pp1alpha-96A Protein phosphatase 1alpha at 96A 0.032
Prx2540-2 Peroxiredoxin 2540 0.032
p53 CG33336 gene product from transcript CG33336-RB 0.032
trpml transient receptor potential mucolipin 0.032
rut rutabaga 0.032
Tdc2 Tyrosine decarboxylase 2 0.032
Hsp23 Heat shock protein 23 0.031
CG11876 CG11876 gene product from transcript CG11876-RA 0.030
Smox Smad on X 0.030
RagA CG11968 gene product from transcript CG11968-RA 0.030
yata CG1973 gene product from transcript CG1973-RA 0.030
sra sarah 0.030
kl-5 male fertility factor kl5 0.030
Pglym78 Phosphoglyceromutase 0.029
Rheb CG1081 gene product from transcript CG1081-RA 0.029
Irc Immune-regulated catalase 0.029
Mef2 Myocyte enhancer factor 2 0.029
CG9796 CG9796 gene product from transcript CG9796-RA 0.028
CG7998 CG7998 gene product from transcript CG7998-RA 0.027
Rac2 CG8556 gene product from transcript CG8556-RA 0.027
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 0.999
TP53 tumor protein p53 0.991
CAV1 caveolin 1, caveolae protein, 22kDa 0.989
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.987
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.983
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.971
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.927
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.925
IL8 interleukin 8 0.910
FKBP1A FK506 binding protein 1A, 12kDa 0.909
IL1R1 interleukin 1 receptor, type I 0.906
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.901
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.882
HBB hemoglobin, beta 0.880
PRDX1 peroxiredoxin 1 0.868
NCF1 neutrophil cytosolic factor 1 0.866
TTR transthyretin 0.842
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.811
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.797
ESR1 estrogen receptor 1 0.782
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.762
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.748
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.747
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.746
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.744
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.741
PLAUR plasminogen activator, urokinase receptor 0.739
JUN jun proto-oncogene 0.706
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.700
BIRC3 baculoviral IAP repeat containing 3 0.700
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.684
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.669
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.668
CXCL3 chemokine (C-X-C motif) ligand 3 0.663
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.650
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.646
SOD1 superoxide dismutase 1, soluble 0.643
NCF4 neutrophil cytosolic factor 4, 40kDa 0.640
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.630
CXCL2 chemokine (C-X-C motif) ligand 2 0.614
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.611
HBA2 hemoglobin, alpha 2 0.599
IL1B interleukin 1, beta 0.584
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.562
HTT huntingtin 0.559
CCNE1 cyclin E1 0.551
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.535
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.532
SOCS3 suppressor of cytokine signaling 3 0.521
TXN thioredoxin 0.519
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.514
TRAF2 TNF receptor-associated factor 2 0.512
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.509
BMP2 bone morphogenetic protein 2 0.504
MDH1 malate dehydrogenase 1, NAD (soluble) 0.496
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.478
TGFB1 transforming growth factor, beta 1 0.476
BAD BCL2-associated agonist of cell death 0.475
ENG endoglin 0.462
FGA fibrinogen alpha chain 0.448
TSC2 tuberous sclerosis 2 0.441
GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase) 0.434
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.431
THBS1 thrombospondin 1 0.430
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.420
INSR insulin receptor 0.412
TICAM2 toll-like receptor adaptor molecule 2 0.410
HBG2 hemoglobin, gamma G 0.408
CCL20 chemokine (C-C motif) ligand 20 0.397
PDZD11 PDZ domain containing 11 0.396
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.383
MAPT microtubule-associated protein tau 0.381
MAPK8 mitogen-activated protein kinase 8 0.377
LTBP2 latent transforming growth factor beta binding protein 2 0.371
RIPK2 receptor-interacting serine-threonine kinase 2 0.362
HSPB8 heat shock 22kDa protein 8 0.360
BCAP31 B-cell receptor-associated protein 31 0.358
IRAK2 interleukin-1 receptor-associated kinase 2 0.358
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.351
ARFIP2 ADP-ribosylation factor interacting protein 2 0.346
RB1 retinoblastoma 1 0.345
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.342
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.341
NRP1 neuropilin 1 0.339
CYBA cytochrome b-245, alpha polypeptide 0.333
CDC25A cell division cycle 25 homolog A (S. pombe) 0.332
ADAM15 ADAM metallopeptidase domain 15 0.331
NOSTRIN nitric oxide synthase trafficker 0.327
BCL2L1 BCL2-like 1 0.316
GSK3B glycogen synthase kinase 3 beta 0.313
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.313
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.307
VEGFA vascular endothelial growth factor A 0.306
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 0.304
RICTOR RPTOR independent companion of MTOR, complex 2 0.304
SMAD7 SMAD family member 7 0.303
LAT linker for activation of T cells 0.302
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.300
CREBBP CREB binding protein 0.293
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.280
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 0.999
Trp53 transformation related protein 53 0.997
Ptgs2 prostaglandin-endoperoxide synthase 2 0.996
Tgfb1 transforming growth factor, beta 1 0.994
Pten phosphatase and tensin homolog 0.985
Tlr4 toll-like receptor 4 0.981
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.966
Tlr2 toll-like receptor 2 0.953
Apoe apolipoprotein E 0.947
Il10 interleukin 10 0.942
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.895
Mcl1 myeloid cell leukemia sequence 1 0.890
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.880
Mapk14 mitogen-activated protein kinase 14 0.861
Lyz2 lysozyme 2 0.847
Socs1 suppressor of cytokine signaling 1 0.844
Myd88 myeloid differentiation primary response gene 88 0.840
Fbn1 fibrillin 1 0.828
Vdr vitamin D receptor 0.827
Bax BCL2-associated X protein 0.804
Ifng interferon gamma 0.783
Prf1 perforin 1 (pore forming protein) 0.782
Inpp5d inositol polyphosphate-5-phosphatase D 0.749
Vegfa vascular endothelial growth factor A 0.738
Col1a1 collagen, type I, alpha 1 0.735
Mmp9 matrix metallopeptidase 9 0.732
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.708
Tgfbr2 transforming growth factor, beta receptor II 0.688
Stat1 signal transducer and activator of transcription 1 0.686
Trim30d tripartite motif-containing 30D 0.659
Rag1 recombination activating gene 1 0.628
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.614
Ikbkg inhibitor of kappaB kinase gamma 0.597
Sykb spleen tyrosine kinase 0.595
Runx2 runt related transcription factor 2 0.581
Ccl2 chemokine (C-C motif) ligand 2 0.568
Hbb-b1 hemoglobin, beta adult major chain 0.566
Nos3 nitric oxide synthase 3, endothelial cell 0.551
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.540
Nos2 nitric oxide synthase 2, inducible 0.537
H2-D1 histocompatibility 2, D region locus 1 0.535
Cd44 CD44 antigen 0.525
Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 0.520
Il6 interleukin 6 0.517
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.505
Stat3 signal transducer and activator of transcription 3 0.503
Tcirg1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 0.500
Insr insulin receptor 0.499
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.496
Fgfr1 fibroblast growth factor receptor 1 0.484
Ldlr low density lipoprotein receptor 0.483
Ccr2 chemokine (C-C motif) receptor 2 0.481
Ren1 renin 1 structural 0.480
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.473
Fasl Fas ligand (TNF superfamily, member 6) 0.473
Vav2 vav 2 oncogene 0.471
Notch2 Notch gene homolog 2 (Drosophila) 0.464
B2m beta-2 microglobulin 0.451
Il6st interleukin 6 signal transducer 0.451
Ncoa3 nuclear receptor coactivator 3 0.449
Thrb thyroid hormone receptor beta 0.442
Cd40 CD40 antigen 0.434
Igh immunoglobulin heavy chain complex 0.428
Mdm2 transformed mouse 3T3 cell double minute 2 0.427
Nos1 nitric oxide synthase 1, neuronal 0.426
Tgfbr1 transforming growth factor, beta receptor I 0.420
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.414
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.396
Bcl2 B-cell leukemia/lymphoma 2 0.393
Idua iduronidase, alpha-L- 0.392
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.391
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.391
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.384
Casp8 caspase 8 0.384
Itgal integrin alpha L 0.379
Lepr leptin receptor 0.378
Ikbkb inhibitor of kappaB kinase beta 0.374
Lair1 leukocyte-associated Ig-like receptor 1 0.373
Lyst lysosomal trafficking regulator 0.362
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.360
Mdm4 transformed mouse 3T3 cell double minute 4 0.360
Cd14 CD14 antigen 0.358
Pyhin1 pyrin and HIN domain family, member 1 0.352
Csf1 colony stimulating factor 1 (macrophage) 0.351
Hif1a hypoxia inducible factor 1, alpha subunit 0.346
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.346
Il2rg interleukin 2 receptor, gamma chain 0.346
Tpo thyroid peroxidase 0.335
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.333
Clec4e C-type lectin domain family 4, member e 0.331
Apc adenomatosis polyposis coli 0.329
Wwox WW domain-containing oxidoreductase 0.327
Plat plasminogen activator, tissue 0.326
Gzmk granzyme K 0.324
Ptrf polymerase I and transcript release factor 0.315
Kit kit oncogene 0.314
Hhat hedgehog acyltransferase 0.314
Atxn1 ataxin 1 0.313
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.310
Ccr1 chemokine (C-C motif) receptor 1 0.303
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hbb hemoglobin, beta 0.713
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.416
Socs3 suppressor of cytokine signaling 3 0.312
Alas2 aminolevulinate, delta-, synthase 2 0.201
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.187
Irs1 insulin receptor substrate 1 0.179
RT1-M5 RT1 class Ib, locus M5 0.174
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.171
Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.165
Agtr1a angiotensin II receptor, type 1a 0.149
Hmox1 heme oxygenase (decycling) 1 0.147
Hspa1a heat shock 70kD protein 1A 0.138
LOC689064 beta-globin 0.137
Dmgdh dimethylglycine dehydrogenase 0.135
Cd4 Cd4 molecule 0.133
Il1r1 interleukin 1 receptor, type I 0.129
LOC100134871 beta globin minor gene 0.123
Ngf nerve growth factor (beta polypeptide) 0.119
Met met proto-oncogene 0.116
Hck hemopoietic cell kinase 0.113
Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 0.111
Icam1 intercellular adhesion molecule 1 0.111
Anxa5 annexin A5 0.111
Serpina11 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 0.110
Tgfbr2 transforming growth factor, beta receptor II 0.109
Il4ra interleukin 4 receptor, alpha 0.108
Syngr2 synaptogyrin 2 0.105
Bcl2 B-cell CLL/lymphoma 2 0.105
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.105
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.103
Anxa4 annexin A4 0.101
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.101
Zfp36l1 zinc finger protein 36, C3H type-like 1 0.100
Gata1 GATA binding protein 1 0.099
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.099
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.097
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.092
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.091
Mpeg1 macrophage expressed 1 0.089
Hspd1 heat shock protein 1 (chaperonin) 0.089
Vom2r27 vomeronasal 2 receptor, 27 0.086
C8b complement component 8, beta polypeptide 0.086
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.085
Pla1a phospholipase A1 member A 0.084
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.082
Ghr growth hormone receptor 0.081
Tp53 tumor protein p53 0.081
Prrx1 paired related homeobox 1 0.081
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.080
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.080
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.080
Creb1 cAMP responsive element binding protein 1 0.080
Fga fibrinogen alpha chain 0.079
Itgam integrin, alpha M 0.079
LOC100363783 rCG53773-like 0.079
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.079
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.079
Clec11a C-type lectin domain family 11, member a 0.078
Pde5a phosphodiesterase 5A, cGMP-specific 0.078
Myo1g myosin IG 0.078
Pgr progesterone receptor 0.077
Ereg epiregulin 0.077
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.077
Ifitm3 interferon induced transmembrane protein 3 0.076
Akr1c18 aldo-keto reductase family 1, member C18 0.076
Hyal2 hyaluronoglucosaminidase 2 0.076
Ggt5 gamma-glutamyltransferase 5 0.075
Prkcd protein kinase C, delta 0.074
Il1rl1 interleukin 1 receptor-like 1 0.074
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.074
LOC100365106 rCG32755-like 0.073
Ccnd3 cyclin D3 0.073
Sirpa signal-regulatory protein alpha 0.073
Il18 interleukin 18 0.072
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.072
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.072
Syt4 synaptotagmin IV 0.072
Cox6a1 cytochrome c oxidase, subunit VIa, polypeptide 1 0.072
Dlat dihydrolipoamide S-acetyltransferase 0.072
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.071
Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 0.071
Sell selectin L 0.070
LOC60591 calcium-activated potassium channel beta subunit 0.070
Hspb1 heat shock protein 1 0.069
Proc protein C 0.069
Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 0.069
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.069
Lyz2 lysozyme 2 0.068
Il6 interleukin 6 0.066
Gif gastric intrinsic factor 0.065
Acot2 acyl-CoA thioesterase 2 0.065
Cd200r1 CD200 receptor 1 0.065
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.065
Dnah1 dynein, axonemal, heavy chain 1 0.064
Gjb5 gap junction protein, beta 5 0.064
Il1b interleukin 1 beta 0.064
Cyb5a cytochrome b5 type A (microsomal) 0.064
Flt1 FMS-related tyrosine kinase 1 0.064
Hbb-b1 hemoglobin, beta adult major chain 0.063
Foxd3 forkhead box D3 0.063