The network for 'regulation of mitotic cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.995
ZDS2 Zds2p 0.946
BUB3 Bub3p 0.935
CDC14 Cdc14p 0.927
CDC28 Cdc28p 0.913
PBS2 Pbs2p 0.867
CDC55 Cdc55p 0.855
PPH22 Pph22p 0.807
KEL1 Kel1p 0.790
GIC1 Gic1p 0.777
DOC1 Doc1p 0.770
RFC5 Rfc5p 0.712
CDC25 Cdc25p 0.701
CDC20 Cdc20p 0.693
CDC16 Cdc16p 0.681
PPH21 Pph21p 0.680
CKA2 Cka2p 0.650
PPZ1 Ppz1p 0.633
CLA4 Cla4p 0.627
CAB3 Cab3p 0.528
GIC2 Gic2p 0.514
FAR1 Far1p 0.508
SLK19 Slk19p 0.472
BCK1 Bck1p 0.455
ZDS1 Zds1p 0.435
CLB5 Clb5p 0.429
RAD24 Rad24p 0.412
CDC23 Cdc23p 0.410
BUB1 Bub1p 0.405
CDC48 Cdc48p 0.404
CLB3 Clb3p 0.399
RPB3 Rpb3p 0.394
CDC27 Cdc27p 0.391
BCK2 Bck2p 0.390
PDS1 Pds1p 0.374
RDH54 Rdh54p 0.374
SKP1 Skp1p 0.371
SCC2 Scc2p 0.369
SSK2 Ssk2p 0.366
CDC12 Cdc12p 0.362
PSR2 Psr2p 0.343
CKS1 Cks1p 0.338
NIS1 Nis1p 0.324
HSL1 Hsl1p 0.324
MCD1 Mcd1p 0.321
IML3 Iml3p 0.319
PUB1 Pub1p 0.308
CDC5 Cdc5p 0.306
DPB2 Dpb2p 0.305
RAD54 Rad54p 0.300
GCN5 Gcn5p 0.298
BFA1 Bfa1p 0.298
TEM1 Tem1p 0.296
APC1 Apc1p 0.294
CKB1 Ckb1p 0.289
GBP2 Gbp2p 0.289
CBF2 Cbf2p 0.288
RAD53 Rad53p 0.286
SLD3 Sld3p 0.275
ASF1 Asf1p 0.271
HHT1 Hht1p 0.270
APC4 Apc4p 0.268
YBP2 Ybp2p 0.265
APC2 Apc2p 0.263
CLB2 Clb2p 0.260
CDC26 Cdc26p 0.254
PSK1 Psk1p 0.241
TFG1 Tfg1p 0.241
KSS1 Kss1p 0.234
THO2 Tho2p 0.230
BIM1 Bim1p 0.229
VHS3 Vhs3p 0.229
STU1 Stu1p 0.228
MCM10 Mcm10p 0.227
TPD3 Tpd3p 0.226
MET4 Met4p 0.221
MMS1 Mms1p 0.220
KIP2 Kip2p 0.216
MND2 Mnd2p 0.216
NDC1 Ndc1p 0.214
RAD50 Rad50p 0.212
DDC1 Ddc1p 0.211
CDC40 Cdc40p 0.206
RPT3 Rpt3p 0.205
PKH1 Pkh1p 0.204
PLC1 Plc1p 0.201
RMD5 Rmd5p 0.201
CLB4 Clb4p 0.200
PSR1 Psr1p 0.199
YNG1 Yng1p 0.199
SLX8 Slx8p 0.199
RCO1 Rco1p 0.198
DMA1 Dma1p 0.198
BEM3 Bem3p 0.197
HHT2 Hht2p 0.195
STE20 Ste20p 0.193
CDH1 Cdh1p 0.193
CLN2 Cln2p 0.193
ASK10 Ask10p 0.190
NUD1 Nud1p 0.189
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
mat-3 Protein MAT-3 0.815
lag-1 Protein LAG-1 0.575
klp-19 Protein KLP-19 0.537
dsh-2 Protein DSH-2 0.535
skp-1 Protein SKP-1 0.508
wrm-1 Protein WRM-1 0.499
CELE_C24H12.5 Protein C24H12.5 0.418
csn-5 Protein CSN-5 0.413
mom-2 Protein MOM-2 0.404
rnr-1 Protein RNR-1 0.400
cyk-4 Protein CYK-4 0.400
bar-1 Protein BAR-1 0.370
ima-3 Protein IMA-3 0.365
hcf-1 Protein HCF-1 0.333
H43E16.1 Protein H43E16.1 0.324
egl-18 Protein EGL-18 0.313
CELE_Y69A2AR.16 Protein Y69A2AR.16 0.302
mex-5 Protein MEX-5 0.291
mcm-7 Protein MCM-7 0.289
hsp-16.48 Protein HSP-16.48 0.288
trr-1 Protein TRR-1 0.271
npp-1 Protein NPP-1 0.264
nck-1 Protein NCK-1 0.263
imb-2 Protein IMB-2 0.261
CELE_C39E9.12 Protein C39E9.12 0.254
oma-2 Protein OMA-2 0.254
gpr-1 Protein GPR-1 0.249
pha-4 Protein PHA-4 0.249
smc-3 Protein SMC-3 0.245
scc-1 Protein SCC-1 0.244
hpo-10 Protein HPO-10 0.243
cdc-6 Protein CDC-6 0.239
kle-2 Protein KLE-2 0.235
daf-1 Protein DAF-1 0.231
sas-5 Protein SAS-5 0.220
bub-1 Protein BUB-1 0.212
icp-1 Protein ICP-1 0.211
rpl-4 Protein RPL-4 0.205
rpa-1 Protein RPA-1 0.201
scc-3 Protein SCC-3 0.200
plk-1 Protein PLK-1 0.200
his-6 Protein HIS-6 0.198
mau-2 Protein MAU-2 0.194
cul-2 Protein CUL-2 0.194
cpb-1 Protein CPB-1 0.194
hpo-32 Protein HPO-32 0.189
mcm-5 Protein MCM-5 0.187
zen-4 Protein ZEN-4 0.186
let-99 Protein LET-99 0.184
asd-1 Protein ASD-1 0.179
CELE_C23G10.8 Protein C23G10.8 0.178
lin-12 Protein LIN-12 0.177
CELE_C10C6.6 Protein C10C6.6 0.173
daz-1 Protein DAZ-1 0.173
cec-9 Protein CEC-9 0.173
F39B2.1 Protein F39B2.1 0.173
nhr-6 Protein NHR-6 0.168
him-1 Protein HIM-1 0.166
csn-6 Protein CSN-6 0.164
brp-1 Protein BRP-1 0.163
acs-4 Protein ACS-4 0.160
igcm-3 Protein IGCM-3 0.159
pry-1 Protein PRY-1 0.158
C48B6.3 Protein C48B6.3 0.158
daf-2 Protein DAF-2 0.157
M03C11.8 Protein M03C11.8 0.154
dut-1 Protein DUT-1 0.153
sel-8 Protein SEL-8 0.148
chd-7 Protein CHD-7 0.148
CELE_K08F4.1 Protein K08F4.1 0.144
npp-2 Protein NPP-2 0.141
pri-2 Protein PRI-2 0.139
eor-1 Protein EOR-1 0.138
pie-1 Protein PIE-1 0.135
F33D11.10 Protein F33D11.10 0.134
daf-21 Protein DAF-21 0.134
set-1 Protein SET-1 0.134
mei-1 Protein MEI-1 0.134
ztf-7 Protein ZTF-7 0.132
srgp-1 Protein SRGP-1 0.131
npp-7 Protein NPP-7 0.130
R05D3.3 Protein R05D3.3 0.130
T19H12.2 Protein T19H12.2 0.129
capg-2 Protein CAPG-2 0.128
isw-1 Protein ISW-1 0.126
csn-1 Protein CSN-1 0.126
hrpf-2 Protein HRPF-2 0.126
H05C05.2 Protein H05C05.2 0.125
xpo-1 Protein XPO-1 0.125
hsp-16.2 Protein HSP-16.2 0.124
vang-1 Protein VANG-1 0.123
spe-26 Protein SPE-26 0.121
mel-28 Protein MEL-28 0.121
nhr-67 Protein NHR-67 0.121
F10E7.11 Protein F10E7.11 0.121
T22C1.1 Protein T22C1.1 0.119
nasp-2 Protein NASP-2 0.119
crt-1 Protein CRT-1 0.116
gad-1 Protein GAD-1 0.116
F56D2.6 Protein F56D2.6 0.115
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cxcr4b chemokine (C-X-C motif), receptor 4b 0.360
rbb4 retinoblastoma binding protein 4 0.309
efnb2a ephrin B2a 0.290
wnt11r wingless-type MMTV integration site family, member 11, related 0.279
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.235
pax2a paired box gene 2a 0.230
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.205
smad9 MAD homolog 9 (Drosophila) 0.201
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.190
pea3 ETS-domain transcription factor pea3 0.167
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.164
kdrl kinase insert domain receptor like 0.162
zff9 zinc finger protein 9 0.151
sae1 SUMO1 activating enzyme subunit 1 0.145
spry4 sprouty (Drosophila) homolog 4 0.143
myca myelocytomatosis oncogene a 0.141
gro2 groucho 2 0.141
rrm1 ribonucleotide reductase M1 polypeptide 0.139
nusap1 nucleolar and spindle associated protein 1 0.128
prdm1a PR domain containing 1a, with ZNF domain 0.124
ncapg non-SMC condensin I complex, subunit G 0.118
pcna proliferating cell nuclear antigen 0.118
her6 hairy-related 6 0.115
sox2 SRY-box containing gene 2 0.113
twist1a twist1a 0.112
mmp2 matrix metalloproteinase 2 0.109
notch1a notch homolog 1a 0.107
ccna2 cyclin A2 0.107
fgf17 fibroblast growth factor 17 0.106
cdk2 cyclin-dependent kinase 2 0.105
dtl denticleless homolog (Drosophila) 0.104
csnk1da casein kinase 1, delta a 0.102
dla deltaA 0.102
brd2a bromodomain-containing 2a 0.101
kif23 kinesin family member 23 0.099
osr2 odd-skipped related 2 (Drosophila) 0.096
acvr1l activin A receptor, type I like 0.095
LOC566708 FL cytokine receptor-like 0.093
si:ch211-215h6.2 si:ch211-215h6.2 0.093
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.091
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.085
krcp kelch repeat-containing protein 0.085
per3 period homolog 3 (Drosophila) 0.085
stil TAL1 (SCL) interrupting locus 0.085
axin1 axin 1 0.084
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.083
bmp2b bone morphogenetic protein 2b 0.082
wnt2 wingless-type MMTV integration site family member 2 0.081
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.081
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.081
ncor1 nuclear receptor co-repressor 1 0.080
gmnn geminin, DNA replication inhibitor 0.079
birc5b baculoviral IAP repeat-containing 5B 0.078
scrib scribbled homolog (Drosophila) 0.078
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.076
wnt4a wingless-type MMTV integration site family, member 4a 0.075
skp2 S-phase kinase-associated protein 2 (p45) 0.073
ascl1a achaete-scute complex-like 1a (Drosophila) 0.072
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.071
orc6 origin recognition complex, subunit 6 0.070
bcl2 B-cell leukemia/lymphoma 2 0.070
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.067
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.066
sfrp5 secreted frizzled-related protein 5 0.065
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.065
wls wntless homolog (Drosophila) 0.064
zgc:110113 zgc:110113 0.063
suv39h1b suppressor of variegation 3-9 homolog 1b 0.063
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.063
emx3 empty spiracles homeobox 3 0.062
smad1 MAD homolog 1 (Drosophila) 0.062
cdt1 chromatin licensing and DNA replication factor 1 0.061
si:ch211-244o22.2 si:ch211-244o22.2 0.061
ccnb1 cyclin B1 0.060
plk1 polo-like kinase 1 (Drosophila) 0.060
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.060
runx2a runt-related transcription factor 2a 0.059
fgf3 fibroblast growth factor 3 0.059
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.058
slbp stem-loop binding protein 0.058
wnt10a wingless-type MMTV integration site family, member 10a 0.057
mapk3 mitogen-activated protein kinase 3 0.056
nfe2l3 nuclear factor (erythroid-derived 2)-like 3 0.055
notch3 notch homolog 3 0.055
fgfr1a fibroblast growth factor receptor 1a 0.055
boc brother of CDO 0.055
cdc25 cell division cycle 25 homolog 0.054
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.054
fzd7b frizzled homolog 7b 0.053
wnt1 wingless-type MMTV integration site family, member 1 0.053
trip13 thyroid hormone receptor interactor 13 0.053
syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae) 0.053
gdf6a growth differentiation factor 6a 0.052
hdac3 histone deacetylase 3 0.052
tbx5a T-box 5a 0.051
bcl2l1 bcl2-like 1 0.050
aplnrb apelin receptor b 0.049
mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.049
pak2b p21 (CDKN1A)-activated kinase 2b 0.049
hoxa13b homeo box A13b 0.049
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Akt1 CG4006 gene product from transcript CG4006-RA 0.995
Mad Mothers against dpp 0.990
asp abnormal spindle 0.988
polo CG12306 gene product from transcript CG12306-RA 0.977
east enhanced adult sensory threshold 0.975
Egfr Epidermal growth factor receptor 0.973
CycB Cyclin B 0.970
yki yorkie 0.968
tefu telomere fusion 0.968
Taf1 TBP-associated factor 1 0.939
Cp190 Centrosomal protein 190kD 0.938
lok loki 0.916
brm brahma 0.911
CSN5 COP9 complex homolog subunit 5 0.911
p53 CG33336 gene product from transcript CG33336-RB 0.908
Su(H) Suppressor of Hairless 0.907
ago archipelago 0.901
CG9772 CG9772 gene product from transcript CG9772-RB 0.894
Stat92E Signal-transducer and activator of transcription protein at 92E 0.886
Smox Smad on X 0.880
hyd hyperplastic discs 0.877
CG4680 CG4680 gene product from transcript CG4680-RA 0.875
E(spl) Enhancer of split 0.853
Ras85D Ras oncogene at 85D 0.841
Rbf Retinoblastoma-family protein 0.822
ctp cut up 0.809
gro groucho 0.764
msps mini spindles 0.760
skd skuld 0.734
HLHm7 E(spl) region transcript m7 0.720
emc extra macrochaetae 0.715
CycE Cyclin E 0.712
Mcm10 Sensitized chromosome inheritance modifier 19 0.697
HLHmgamma E(spl) region transcript mgamma 0.694
fu fused 0.677
tkv thickveins 0.664
esc extra sexcombs 0.650
Myb Myb oncogene-like 0.645
ci cubitus interruptus 0.638
fzy fizzy 0.626
Iswi Imitation SWI 0.625
EcR Ecdysone receptor 0.623
okr okra 0.621
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.619
phl pole hole 0.612
spn-B spindle B 0.604
CycB3 Cyclin B3 0.589
slmb supernumerary limbs 0.579
Chro Chromator 0.577
Mer Merlin 0.571
orb oo18 RNA-binding protein 0.561
smt3 CG4494 gene product from transcript CG4494-RA 0.561
Cdc37 CG12019 gene product from transcript CG12019-RA 0.557
HLHmbeta E(spl) region transcript mbeta 0.556
Top1 Topoisomerase 1 0.551
Ser Serrate 0.550
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.550
Pp4-19C Protein phosphatase 19C 0.541
Klp10A CG1453 gene product from transcript CG1453-RA 0.539
pie pineapple eye 0.534
Bap55 Brahma associated protein 55kD 0.530
mi minus 0.513
emb embargoed 0.510
kis kismet 0.507
HLHm5 E(spl) region transcript m5 0.506
sd scalloped 0.504
spn-E spindle E 0.503
CycG Cyclin G 0.494
Sse Separase 0.493
egl egalitarian 0.484
Snr1 Snf5-related 1 0.480
MED31 Mediator complex subunit 31 0.476
mus304 mutagen-sensitive 304 0.473
Spc105R Spc105-related 0.458
ttv tout-velu 0.458
cutlet CG33122 gene product from transcript CG33122-RA 0.456
lds lodestar 0.451
dpp decapentaplegic 0.445
Ssrp Structure specific recognition protein 0.444
E(z) Enhancer of zeste 0.442
Art1 Arginine methyltransferase 1 0.440
mus301 mutagen-sensitive 301 0.438
ash2 absent, small, or homeotic discs 2 0.438
Grip84 gamma-tubulin ring protein 84 0.433
tld tolloid 0.433
gbb glass bottom boat 0.431
cid centromere identifier 0.431
Dref DNA replication-related element factor 0.430
rux roughex 0.423
Dad Daughters against dpp 0.422
nudE CG8104 gene product from transcript CG8104-RB 0.421
Top2 Topoisomerase 2 0.418
mei-41 meiotic 41 0.413
Chc Clathrin heavy chain 0.412
dmt dalmatian 0.408
usp ultraspiracle 0.407
Stim Stromal interaction molecule 0.403
ovo CG6824 gene product from transcript CG6824-RE 0.402
Ote Otefin 0.397
hh hedgehog 0.382
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
RB1 retinoblastoma 1 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
EGFR epidermal growth factor receptor 1.000
H2AFX H2A histone family, member X 0.999
BRCA1 breast cancer 1, early onset 0.999
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.999
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.999
PLK1 polo-like kinase 1 0.998
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.998
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.995
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.994
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.993
CCNA2 cyclin A2 0.991
RPA1 replication protein A1, 70kDa 0.990
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.988
E2F1 E2F transcription factor 1 0.987
CCNB1 cyclin B1 0.987
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.987
CDK2 cyclin-dependent kinase 2 0.982
BTRC beta-transducin repeat containing 0.981
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.976
RBL1 retinoblastoma-like 1 (p107) 0.973
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.969
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.964
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.962
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.962
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.953
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.935
BCL2L1 BCL2-like 1 0.926
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.920
XIAP X-linked inhibitor of apoptosis 0.914
BCL2 B-cell CLL/lymphoma 2 0.911
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.907
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.898
NBN nibrin 0.896
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.893
TFDP1 transcription factor Dp-1 0.885
CCND3 cyclin D3 0.870
CAV1 caveolin 1, caveolae protein, 22kDa 0.853
SKP2 S-phase kinase-associated protein 2 (p45) 0.851
CDC25A cell division cycle 25 homolog A (S. pombe) 0.848
CUL1 cullin 1 0.844
COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.838
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.829
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.824
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.818
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.812
HDAC1 histone deacetylase 1 0.805
TOPBP1 topoisomerase (DNA) II binding protein 1 0.801
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.797
RBL2 retinoblastoma-like 2 (p130) 0.790
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.786
TOLLIP toll interacting protein 0.783
MDC1 mediator of DNA-damage checkpoint 1 0.781
PRKCA protein kinase C, alpha 0.781
CBX5 chromobox homolog 5 0.775
CDK8 cyclin-dependent kinase 8 0.775
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.768
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.762
SKP1 S-phase kinase-associated protein 1 0.762
GSK3B glycogen synthase kinase 3 beta 0.753
MAPK1 mitogen-activated protein kinase 1 0.747
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.745
CUL2 cullin 2 0.743
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.738
JAG1 jagged 1 0.737
CNOT8 CCR4-NOT transcription complex, subunit 8 0.734
AR androgen receptor 0.733
ARID1A AT rich interactive domain 1A (SWI-like) 0.729
EIF3H eukaryotic translation initiation factor 3, subunit H 0.716
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.702
CSNK2B casein kinase 2, beta polypeptide 0.701
IER3 immediate early response 3 0.687
JAK2 Janus kinase 2 0.680
CDT1 chromatin licensing and DNA replication factor 1 0.674
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.671
CDK1 cyclin-dependent kinase 1 0.670
RFWD2 ring finger and WD repeat domain 2 0.670
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.662
CSNK1E casein kinase 1, epsilon 0.659
MYST2 MYST histone acetyltransferase 2 0.653
CDC16 cell division cycle 16 homolog (S. cerevisiae) 0.652
MAPK14 mitogen-activated protein kinase 14 0.640
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.638
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.631
CDC25C cell division cycle 25 homolog C (S. pombe) 0.630
BRCA2 breast cancer 2, early onset 0.629
HDAC3 histone deacetylase 3 0.627
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.627
CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.618
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.614
YY1 YY1 transcription factor 0.614
RAD50 RAD50 homolog (S. cerevisiae) 0.600
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.597
NOTCH1 notch 1 0.593
PAX3 paired box 3 0.584
COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 0.584
TOP2A topoisomerase (DNA) II alpha 170kDa 0.583
EP300 E1A binding protein p300 0.579
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.999
Pten phosphatase and tensin homolog 0.994
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.989
Shh sonic hedgehog 0.986
Ctnnb1 catenin (cadherin associated protein), beta 1 0.985
Gli3 GLI-Kruppel family member GLI3 0.980
Cdk4 cyclin-dependent kinase 4 0.967
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.960
Apc adenomatosis polyposis coli 0.941
Notch1 Notch gene homolog 1 (Drosophila) 0.933
E2f1 E2F transcription factor 1 0.932
Brca1 breast cancer 1 0.925
Mdm2 transformed mouse 3T3 cell double minute 2 0.923
Smad4 MAD homolog 4 (Drosophila) 0.914
Ccnb1 cyclin B1 0.909
Brca2 breast cancer 2 0.908
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.906
Rbl1 retinoblastoma-like 1 (p107) 0.903
Pcna proliferating cell nuclear antigen 0.889
Tcf3 transcription factor 3 0.887
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.886
Prc1 protein regulator of cytokinesis 1 0.875
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.861
Cbl Casitas B-lineage lymphoma 0.845
Arid1b AT rich interactive domain 1B (SWI-like) 0.843
Fgfr2 fibroblast growth factor receptor 2 0.815
Cdk2 cyclin-dependent kinase 2 0.799
Tfdp1 transcription factor Dp 1 0.794
Ptch1 patched homolog 1 0.788
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.765
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.757
Skil SKI-like 0.756
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.745
Plk1 polo-like kinase 1 (Drosophila) 0.729
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.698
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.688
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.685
Cdk1 cyclin-dependent kinase 1 0.684
Emx1 empty spiracles homolog 1 (Drosophila) 0.677
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.664
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.664
Meox2 mesenchyme homeobox 2 0.659
Fgfr3 fibroblast growth factor receptor 3 0.656
Grb2 growth factor receptor bound protein 2 0.655
Ccna2 cyclin A2 0.650
Kif11 kinesin family member 11 0.650
Stag1 stromal antigen 1 0.631
Pax3 paired box gene 3 0.628
Nbn nibrin 0.619
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.614
Plk4 polo-like kinase 4 (Drosophila) 0.613
Lmnb1 lamin B1 0.608
Prrx2 paired related homeobox 2 0.601
Ar androgen receptor 0.599
Psen1 presenilin 1 0.579
Cdca5 cell division cycle associated 5 0.570
Sox2 SRY-box containing gene 2 0.567
Orc1 origin recognition complex, subunit 1 0.562
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.555
Hdac1 histone deacetylase 1 0.552
Foxa2 forkhead box A2 0.547
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.534
Stat3 signal transducer and activator of transcription 3 0.534
Hoxa13 homeobox A13 0.529
Hmgb1 high mobility group box 1 0.528
Blm Bloom syndrome, RecQ helicase-like 0.528
Notch2 Notch gene homolog 2 (Drosophila) 0.519
Grb10 growth factor receptor bound protein 10 0.512
H2afx H2A histone family, member X 0.508
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.505
Pum1 pumilio 1 (Drosophila) 0.497
Vangl2 vang-like 2 (van gogh, Drosophila) 0.490
Rarg retinoic acid receptor, gamma 0.486
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.485
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.481
Fgfr1 fibroblast growth factor receptor 1 0.474
Kif20a kinesin family member 20A 0.459
Ccnd1 cyclin D1 0.459
Bcl2 B-cell leukemia/lymphoma 2 0.455
Nog noggin 0.451
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.448
H2afz H2A histone family, member Z 0.446
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.445
Rad51ap1 RAD51 associated protein 1 0.442
Gli2 GLI-Kruppel family member GLI2 0.441
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.440
Pou3f3 POU domain, class 3, transcription factor 3 0.439
Raf1 v-raf-leukemia viral oncogene 1 0.434
Ccne1 cyclin E1 0.434
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.431
Nf1 neurofibromatosis 1 0.431
Npm1 nucleophosmin 1 0.424
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.422
Rac1 RAS-related C3 botulinum substrate 1 0.421
Cdt1 chromatin licensing and DNA replication factor 1 0.416
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.413
Kif23 kinesin family member 23 0.411
Tgfbr2 transforming growth factor, beta receptor II 0.408
Ckap2 cytoskeleton associated protein 2 0.402
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Rattus norvegicus
Name Description Probability Func Analog Organism
Pcna proliferating cell nuclear antigen 0.013
Cdk4 cyclin-dependent kinase 4 0.012
Taok1 TAO kinase 1 0.011