The network for 'regulation of protein ubiquitination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein ubiquitination

Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.

Name Description Probability Func Analog Organism
CTR9 Ctr9p 0.735
CDC16 Cdc16p 0.712
CDC23 Cdc23p 0.644
CDC27 Cdc27p 0.534
RTF1 Rtf1p 0.468
APC2 Apc2p 0.311
SWM1 Swm1p 0.195
CDC26 Cdc26p 0.193
MND2 Mnd2p 0.192
CDC20 Cdc20p 0.187
SPT16 Spt16p 0.184
PAF1 Paf1p 0.172
SIC1 Sic1p 0.172
CKB1 Ckb1p 0.171
CDC28 Cdc28p 0.165
CDC34 Cdc34p 0.165
UFO1 Ufo1p 0.154
APC4 Apc4p 0.146
APC1 Apc1p 0.144
KAR2 Kar2p 0.141
CDH1 Cdh1p 0.139
LEO1 Leo1p 0.125
CKS1 Cks1p 0.125
CDC6 Cdc6p 0.123
LAG2 Lag2p 0.121
APC5 Apc5p 0.119
RPT6 Rpt6p 0.112
AHA1 Aha1p 0.096
DAS1 Das1p 0.096
DOC1 Doc1p 0.087
SIS1 Sis1p 0.086
CAK1 Cak1p 0.082
RPN2 Rpn2p 0.081
SSA2 Ssa2p 0.066
BUL1 Bul1p 0.061
RAD23 Rad23p 0.053
UBR1 Ubr1p 0.051
YDJ1 Ydj1p 0.050
MDN1 Mdn1p 0.048
SLX8 Slx8p 0.048
MAD3 Mad3p 0.048
HSL1 Hsl1p 0.045
SGT2 Sgt2p 0.043
AHP1 Ahp1p 0.042
STI1 Sti1p 0.041
SAP190 Sap190p 0.040
IME2 Ime2p 0.039
HDA2 Hda2p 0.038
SGV1 Sgv1p 0.038
RPN14 Rpn14p 0.038
LHS1 Lhs1p 0.038
VPS9 Vps9p 0.038
UBC4 Ubc4p 0.036
AHC1 Ahc1p 0.034
RPN1 Rpn1p 0.033
MYO5 Myo5p 0.032
APC11 Apc11p 0.032
CDC53 Cdc53p 0.029
RPO21 Rpo21p 0.029
HRT3 Hrt3p 0.028
YLR419W hypothetical protein 0.028
FIN1 Fin1p 0.027
SSA1 Ssa1p 0.027
ESC1 Esc1p 0.026
BTN2 Btn2p 0.025
URN1 Urn1p 0.024
FMP52 Fmp52p 0.024
PBS2 Pbs2p 0.024
GYL1 Gyl1p 0.023
TFA1 Tfa1p 0.023
ROM2 Rom2p 0.022
ATG2 Atg2p 0.022
APC9 Apc9p 0.021
RUB1 Rub1p 0.021
CLB3 Clb3p 0.020
BRO1 Bro1p 0.020
SFB3 Sfb3p 0.020
YRA2 Yra2p 0.020
CUP1-1 Cup1-1p 0.019
SIL1 Sil1p 0.019
SRD1 Srd1p 0.019
ATG9 Atg9p 0.019
HSM3 Hsm3p 0.019
CPR6 Cpr6p 0.019
YJR149W hypothetical protein 0.018
YAP7 Yap7p 0.018
UBP7 Ubp7p 0.018
DCN1 Dcn1p 0.018
DST1 Dst1p 0.018
MLP2 Mlp2p 0.018
LEU2 Leu2p 0.018
ALT1 Alt1p 0.018
RPT1 Rpt1p 0.018
SMA1 Sma1p 0.018
SCJ1 Scj1p 0.018
WWM1 Wwm1p 0.018
BAT2 Bat2p 0.018
ARP10 Arp10p 0.017
SSA3 Ssa3p 0.017
PCL9 Pcl9p 0.017
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
rpt-2 Protein RPT-2 0.035
pas-6 Protein PAS-6 0.025
clic-1 Protein CLIC-1 0.022
R05F9.9 Protein R05F9.9 0.022
pcn-1 Protein PCN-1 0.021
B0041.5 Protein B0041.5 0.021
rol-3 Protein ROL-3 0.020
pup-2 Protein PUP-2 0.020
sli-1 Protein SLI-1 0.020
pas-5 Protein PAS-5 0.020
mcm-3 Protein MCM-3 0.019
pbs-7 Protein PBS-7 0.019
skr-1 Protein SKR-1 0.019
ubxn-1 Protein UBXN-1 0.019
rpn-12 Protein RPN-12 0.018
fli-1 Protein FLI-1 0.018
kin-3 Protein KIN-3 0.018
ttyh-1 Protein TTYH-1 0.018
hpk-1 Protein HPK-1 0.018
madf-5 Protein MADF-5 0.018
stam-1 Protein STAM-1 0.018
pbs-6 Protein PBS-6 0.017
CELE_ZK1025.3 Protein ZK1025.3 0.017
dpy-27 Protein DPY-27 0.017
F28B3.1 Protein F28B3.1 0.017
gck-1 Protein GCK-1 0.017
lin-23 Protein LIN-23 0.017
pop-1 Protein POP-1 0.017
rpn-3 Protein RPN-3 0.017
hgrs-1 Protein HGRS-1 0.017
egl-8 Protein EGL-8 0.017
atg-18 Protein ATG-18 0.017
grd-1 Protein GRD-1 0.016
snr-5 Protein SNR-5 0.016
sym-4 Protein SYM-4 0.016
ubr-1 Protein UBR-1 0.016
uev-1 Protein UEV-1 0.016
CELE_W01G7.4 Protein W01G7.4 0.016
F13B6.1 Protein F13B6.1 0.016
pek-1 Protein PEK-1 0.016
let-60 Protein LET-60 0.016
ztf-7 Protein ZTF-7 0.016
mtk-1 Protein MTK-1 0.016
lin-25 Protein LIN-25 0.015
nipi-3 Protein NIPI-3 0.015
usp-14 Protein USP-14 0.015
gmeb-1 Protein GMEB-1 0.015
dss-1 Protein DSS-1 0.015
pas-4 Protein PAS-4 0.015
mus-81 Protein MUS-81 0.015
T08A11.1 Protein T08A11.1 0.015
sad-1 Protein SAD-1 0.015
CELE_F15A8.6 Protein F15A8.6 0.015
dnj-7 Protein DNJ-7 0.015
pdi-3 Protein PDI-3 0.015
cdd-2 Protein CDD-2 0.015
fkb-6 Protein FKB-6 0.015
sel-12 Protein SEL-12 0.015
R05G6.10 Protein R05G6.10 0.015
clp-2 Protein CLP-2 0.015
tag-296 Protein TAG-296 0.015
sel-2 Protein SEL-2 0.014
R11A8.7 Protein R11A8.7 0.014
cct-7 Protein CCT-7 0.014
mex-3 Protein MEX-3 0.014
tam-1 Protein TAM-1 0.014
kin-4 Protein KIN-4 0.014
let-756 Protein LET-756 0.014
bar-1 Protein BAR-1 0.014
dpy-30 Protein DPY-30 0.014
C02F5.7 Protein C02F5.7 0.014
W04D2.6 Protein W04D2.6 0.014
nap-1 Protein NAP-1 0.014
paa-1 Protein PAA-1 0.014
CELE_Y57E12AL.6 Protein Y57E12AL.6 0.014
CELE_E01G4.6 Protein E01G4.6 0.014
let-711 Protein LET-711 0.014
dpy-31 Protein DPY-31 0.014
imp-2 Protein IMP-2 0.014
daf-21 Protein DAF-21 0.014
ilys-4 Protein ILYS-4 0.014
cdh-10 Protein CDH-10 0.014
F09G2.8 Protein F09G2.8 0.014
T16G1.2 Protein T16G1.2 0.014
nud-2 Protein NUD-2 0.014
F55C12.5 Protein F55C12.5 0.014
tbb-1 Protein TBB-1 0.014
pbs-2 Protein PBS-2 0.014
abl-1 Protein ABL-1 0.014
C28G1.5 Protein C28G1.5 0.014
mel-26 Protein MEL-26 0.014
daz-1 Protein DAZ-1 0.014
bah-1 Protein BAH-1 0.014
soc-2 Protein SOC-2 0.014
uba-1 Protein UBA-1 0.013
ubql-1 Protein UBQL-1 0.013
M01F1.3 Protein M01F1.3 0.013
crt-1 Protein CRT-1 0.013
hcp-1 Protein HCP-1 0.013
CELE_Y46G5A.29 Protein Y46G5A.29 0.013
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.616
tp53 tumor protein p53 0.536
ube2d1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.433
cdh2 cadherin 2, neuronal 0.384
sass6 spindle assembly 6 homolog (C. elegans) 0.347
mib mind bomb 0.329
cdt1 chromatin licensing and DNA replication factor 1 0.325
apc adenomatosis polyposis coli 0.310
jhdm1da jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae) 0.296
nod1 nucleotide-binding oligomerization domain containing 1 0.263
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.260
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.229
gins3 GINS complex subunit 3 0.214
cry3 cryptochrome 3 0.214
hspa4a heat shock protein 4a 0.196
robo3 roundabout homolog 3 0.180
shha sonic hedgehog a 0.175
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.169
ddb2 damage-specific DNA binding protein 2 0.168
gro2 groucho 2 0.155
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.152
aurkb aurora kinase B 0.151
ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2 0.149
LOC557072 caspase recruitment domain-containing protein 11-like 0.146
zgc:174506 zgc:174506 0.144
psmd11b proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b 0.142
orc1 origin recognition complex, subunit 1 0.133
sf3b14 splicing factor 3B 0.128
gmnn geminin, DNA replication inhibitor 0.128
emx2 empty spiracles homeobox 2 0.126
rorab RAR-related orphan receptor A, paralog b 0.125
foxd3 forkhead box D3 0.125
mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.121
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.120
sema3h semaphorin 3h 0.120
smad5 MAD homolog 5 (Drosophila) 0.119
sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like 0.117
zc4h2 zinc finger, C4H2 domain containing 0.113
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.113
snx6 sorting nexin 6 0.110
ntn2 netrin 2 0.110
notch1a notch homolog 1a 0.109
zgc:110113 zgc:110113 0.109
zgc:111821 zgc:111821 0.108
ube2na ubiquitin-conjugating enzyme E2Na 0.108
bglap bone gamma-carboxyglutamate (gla) protein 0.108
gmfb glia maturation factor, beta 0.104
cry-dash cryptochrome DASH 0.103
zgc:55573 zgc:55573 0.099
ube2v2 ubiquitin-conjugating enzyme E2 variant 2 0.098
psmd4b proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b 0.098
mapk7 mitogen-activated protein kinase 7 0.098
tbx24 T-box 24 0.097
nutf2l nuclear transport factor 2, like 0.097
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.097
dag1 dystroglycan 1 0.097
si:ch211-69g19.2 si:ch211-69g19.2 0.096
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.096
supt3h suppressor of Ty 3 homolog (S. cerevisiae) 0.095
ccna2 cyclin A2 0.095
ppil4 peptidylprolyl isomerase (cyclophilin)-like 4 0.094
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.094
rfng radical fringe homolog (Drosophila) 0.094
vldlr very low density lipoprotein receptor 0.092
smarcal1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.091
LOC566708 FL cytokine receptor-like 0.090
phf6 PHD finger protein 6 0.090
ccnb2 cyclin B2 0.090
tfr1a transferrin receptor 1a 0.090
tm9sf2 transmembrane 9 superfamily member 2 0.090
bactin2 bactin2 0.088
orc6 origin recognition complex, subunit 6 0.088
tshz1 teashirt family zinc finger 1 0.087
foxb1.2 forkhead box B1.2 0.086
suv39h1b suppressor of variegation 3-9 homolog 1b 0.085
krt4 keratin 4 0.084
ppp1r7 protein phosphatase 1, regulatory (inhibitor) subunit 7 0.084
epha4a eph receptor A4a 0.084
hlxb9lb homeo box HB9 like b 0.083
dmd dystrophin 0.082
bc2 putative breast adenocarcinoma marker 0.082
slbp stem-loop binding protein 0.082
evx1 even-skipped homeobox 1 0.082
arhgap11a Rho GTPase activating protein 11A 0.082
cdca8 cell division cycle associated 8 0.081
casrl calcium-sensing receptor, like 0.081
ube2nb ubiquitin-conjugating enzyme E2Nb 0.081
ripk2 receptor-interacting serine-threonine kinase 2 0.080
si:dkey-236e20.2 si:dkey-236e20.2 0.080
limk2 LIM domain kinase 2 0.079
sumo1 SMT3 suppressor of mif two 3 homolog 1 (yeast) 0.079
cry1a cryptochrome 1a 0.078
plk1 polo-like kinase 1 (Drosophila) 0.078
rybpa RING1 and YY1 binding protein a 0.078
mapk14a mitogen-activated protein kinase 14a 0.077
wdr48 WD repeat domain 48 0.077
cdc20 cell division cycle 20 homolog 0.077
timm17a translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.077
hsbp1 heat shock factor binding protein 1 0.077
amotl2a angiomotin like 2a 0.077
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
wts warts 0.170
Atg1 Autophagy-specific gene 1 0.154
dsh dishevelled 0.121
ago archipelago 0.080
Rab5 Rab-protein 5 0.080
rap retina aberrant in pattern 0.072
gig gigas 0.068
Lrrk Leucine-rich repeat kinase 0.066
drk downstream of receptor kinase 0.065
Su(H) Suppressor of Hairless 0.062
dos daughter of sevenless 0.061
lid little imaginal discs 0.057
sws swiss cheese 0.047
RASSF8 CG5053 gene product from transcript CG5053-RA 0.037
hpo hippo 0.036
Atg7 Autophagy-specific gene 7 0.035
ci cubitus interruptus 0.031
seq sequoia 0.029
skpA CG16983 gene product from transcript CG16983-RD 0.029
Dad Daughters against dpp 0.029
Arr2 Arrestin 2 0.027
bif bifocal 0.026
milt milton 0.026
kis kismet 0.025
Su(var)205 Suppressor of variegation 205 0.024
Dcp-1 Death caspase-1 0.024
Syx17 Syntaxin 17 0.022
Miro Mitochondrial Rho 0.022
Vhl von Hippel-Lindau 0.022
Vps25 Vacuolar protein sorting 25 0.022
CG13298 CG13298 gene product from transcript CG13298-RA 0.022
yki yorkie 0.021
jing CG9397 gene product from transcript CG9397-RI 0.020
Akt1 CG4006 gene product from transcript CG4006-RA 0.020
gukh GUK-holder 0.020
put punt 0.020
Dap160 Dynamin associated protein 160 0.020
Tsc1 CG6147 gene product from transcript CG6147-RA 0.019
Gga CG3002 gene product from transcript CG3002-RB 0.019
Rpn11 CG18174 gene product from transcript CG18174-RA 0.019
Ube3a Ubiquitin protein ligase E3A 0.019
tefu telomere fusion 0.019
rpr reaper 0.019
MED19 Mediator complex subunit 19 0.019
Exp6 Exportin 6 0.018
park parkin 0.018
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.018
sav salvador 0.018
Dbp73D Dead box protein 73D 0.018
CG11347 CG11347 gene product from transcript CG11347-RE 0.018
Sce Sex combs extra 0.018
cg combgap 0.018
Tak1 TGF-beta activated kinase 1 0.018
Hsc70-4 Heat shock protein cognate 4 0.018
Max CG9648 gene product from transcript CG9648-RA 0.017
Smox Smad on X 0.017
Spc105R Spc105-related 0.017
GckIII Germinal centre kinase III 0.016
morgue modifier of rpr and grim, ubiquitously expressed 0.016
pr-set7 CG3307 gene product from transcript CG3307-RC 0.016
exba extra bases 0.016
Rheb CG1081 gene product from transcript CG1081-RA 0.016
klar klarsicht 0.016
rok Rho-kinase 0.016
Fak56D Focal Adhesion Kinase 0.016
slmb supernumerary limbs 0.016
Ice CG7788 gene product from transcript CG7788-RA 0.016
ninaE neither inactivation nor afterpotential E 0.015
CG13349 CG13349 gene product from transcript CG13349-RA 0.015
cdm cadmus 0.015
bel belle 0.015
mol moladietz 0.015
Mad Mothers against dpp 0.015
RhoBTB CG5701 gene product from transcript CG5701-RA 0.015
sbb scribbler 0.015
Galpha49B G protein alpha49B 0.015
ey eyeless 0.015
Fer2LCH Ferritin 2 light chain homologue 0.015
Z600 CG17962 gene product from transcript CG17962-RA 0.015
Ddx1 Dead-box-1 0.015
Sara Smad anchor for receptor activation 0.015
eya eyes absent 0.014
CG9866 CG9866 gene product from transcript CG9866-RA 0.014
l(2)k14710 lethal (2) k14710 0.014
Rpn2 CG11888 gene product from transcript CG11888-RA 0.014
Atg6 Autophagy-specific gene 6 0.014
Tre1 trapped in endoderm-1 0.014
g garnet 0.014
grh grainy head 0.014
yemalpha yemanuclein alpha 0.014
Nmnat Nicotinamide mononucleotide adenylyltransferase 0.013
CG18178 CG18178 gene product from transcript CG18178-RA 0.013
Dcr-2 Dicer-2 0.013
inaC inactivation no afterpotential C 0.013
Rab7 Rab-protein 7 0.013
ninaC neither inactivation nor afterpotential C 0.013
RagA CG11968 gene product from transcript CG11968-RA 0.013
chp chaoptic 0.013
kn knot 0.013
dlt discs lost 0.013
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SMAD7 SMAD family member 7 0.994
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.994
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.993
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.990
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.986
VCP valosin containing protein 0.985
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.984
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.982
TRAF6 TNF receptor-associated factor 6 0.966
UBC ubiquitin C 0.961
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.959
DAXX death-domain associated protein 0.957
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.949
BIRC3 baculoviral IAP repeat containing 3 0.949
UBE2D2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 0.940
STK4 serine/threonine kinase 4 0.937
TP53 tumor protein p53 0.936
RNF11 ring finger protein 11 0.929
BIRC2 baculoviral IAP repeat containing 2 0.928
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.911
SKP1 S-phase kinase-associated protein 1 0.901
PIAS4 protein inhibitor of activated STAT, 4 0.894
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.881
SMAD1 SMAD family member 1 0.877
TEK TEK tyrosine kinase, endothelial 0.844
PML promyelocytic leukemia 0.819
CUL1 cullin 1 0.795
BCAR1 breast cancer anti-estrogen resistance 1 0.787
BRCA1 breast cancer 1, early onset 0.780
FKBP1A FK506 binding protein 1A, 12kDa 0.754
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.739
FBXW11 F-box and WD repeat domain containing 11 0.736
ARIH2 ariadne homolog 2 (Drosophila) 0.725
RING1 ring finger protein 1 0.722
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.702
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.702
PSEN1 presenilin 1 0.693
HUWE1 HECT, UBA and WWE domain containing 1 0.689
SKP2 S-phase kinase-associated protein 2 (p45) 0.683
SMAD2 SMAD family member 2 0.671
SMAD4 SMAD family member 4 0.639
HSPA1A heat shock 70kDa protein 1A 0.630
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.623
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.622
CBX8 chromobox homolog 8 0.611
MAP2K4 mitogen-activated protein kinase kinase 4 0.610
ANAPC4 anaphase promoting complex subunit 4 0.586
PHAX phosphorylated adaptor for RNA export 0.583
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.568
DTX3L deltex 3-like (Drosophila) 0.551
CAV1 caveolin 1, caveolae protein, 22kDa 0.538
CDK2 cyclin-dependent kinase 2 0.531
UBE2N ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) 0.527
UBA1 ubiquitin-like modifier activating enzyme 1 0.497
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.494
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.479
RNF111 ring finger protein 111 0.477
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.474
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.471
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.467
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.453
RYBP RING1 and YY1 binding protein 0.447
MAGEA3 melanoma antigen family A, 3 0.443
UBQLN1 ubiquilin 1 0.435
SMAD3 SMAD family member 3 0.434
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.429
SIRT2 sirtuin 2 0.426
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.426
IRAK1 interleukin-1 receptor-associated kinase 1 0.417
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.401
RNF2 ring finger protein 2 0.396
ZNF496 zinc finger protein 496 0.391
EID1 EP300 interacting inhibitor of differentiation 1 0.391
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.383
BCL2L1 BCL2-like 1 0.379
TGFBR1 transforming growth factor, beta receptor 1 0.368
HSPA4 heat shock 70kDa protein 4 0.364
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.351
ACVR1B activin A receptor, type IB 0.348
TRAF3 TNF receptor-associated factor 3 0.338
CBX7 chromobox homolog 7 0.335
UBE2M ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) 0.317
TRIM39 tripartite motif containing 39 0.304
RAD18 RAD18 homolog (S. cerevisiae) 0.301
MEOX2 mesenchyme homeobox 2 0.292
MAPK8 mitogen-activated protein kinase 8 0.282
ZNRF1 zinc and ring finger 1 0.278
ACVR1 activin A receptor, type I 0.267
FYN FYN oncogene related to SRC, FGR, YES 0.265
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.262
RAD23B RAD23 homolog B (S. cerevisiae) 0.261
TRIM32 tripartite motif containing 32 0.257
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.254
CCNA2 cyclin A2 0.250
ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) 0.248
SPRY4 sprouty homolog 4 (Drosophila) 0.245
CTAG1B cancer/testis antigen 1B 0.245
BTRC beta-transducin repeat containing 0.243
NOXA1 NADPH oxidase activator 1 0.238
RFWD2 ring finger and WD repeat domain 2 0.237
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 0.872
Mdm2 transformed mouse 3T3 cell double minute 2 0.818
Tlr4 toll-like receptor 4 0.659
Ctnnb1 catenin (cadherin associated protein), beta 1 0.601
Usp18 ubiquitin specific peptidase 18 0.525
Axin1 axin 1 0.506
Cry2 cryptochrome 2 (photolyase-like) 0.482
Clock circadian locomotor output cycles kaput 0.351
Gbp2 guanylate binding protein 2 0.308
Per2 period homolog 2 (Drosophila) 0.284
Vcp valosin containing protein 0.233
Igtp interferon gamma induced GTPase 0.232
Wnt3a wingless-related MMTV integration site 3A 0.221
Lrrk2 leucine-rich repeat kinase 2 0.215
Skil SKI-like 0.194
Iigp1 interferon inducible GTPase 1 0.186
Irgm2 immunity-related GTPase family M member 2 0.186
Gsk3b glycogen synthase kinase 3 beta 0.183
Stat1 signal transducer and activator of transcription 1 0.178
Kl klotho 0.166
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.153
Mdm4 transformed mouse 3T3 cell double minute 4 0.152
Shh sonic hedgehog 0.147
Atg12 autophagy-related 12 (yeast) 0.143
Irf1 interferon regulatory factor 1 0.140
Atf4 activating transcription factor 4 0.135
Gli2 GLI-Kruppel family member GLI2 0.130
Cry1 cryptochrome 1 (photolyase-like) 0.126
Arrb2 arrestin, beta 2 0.125
Emx2 empty spiracles homolog 2 (Drosophila) 0.119
Tgtp2 T-cell specific GTPase 2 0.117
Gbp3 guanylate binding protein 3 0.109
Bmp4 bone morphogenetic protein 4 0.108
Wnt4 wingless-related MMTV integration site 4 0.107
ND6 NADH dehydrogenase subunit 6 0.106
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.104
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.103
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.102
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.100
Pax2 paired box gene 2 0.098
Itga3 integrin alpha 3 0.098
Myd88 myeloid differentiation primary response gene 88 0.095
Gli3 GLI-Kruppel family member GLI3 0.094
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.094
Arrb1 arrestin, beta 1 0.090
Traf6 TNF receptor-associated factor 6 0.089
Irgm1 immunity-related GTPase family M member 1 0.088
Notch1 Notch gene homolog 1 (Drosophila) 0.087
Hspa8 heat shock protein 8 0.087
Ifi47 interferon gamma inducible protein 47 0.083
Hipk1 homeodomain interacting protein kinase 1 0.083
Rpgrip1l Rpgrip1-like 0.078
Otx1 orthodenticle homolog 1 (Drosophila) 0.077
Irf7 interferon regulatory factor 7 0.076
Notch2 Notch gene homolog 2 (Drosophila) 0.075
Gbp7 guanylate binding protein 7 0.073
Ncstn nicastrin 0.072
Gbp6 guanylate binding protein 6 0.068
T brachyury 0.066
Gclm glutamate-cysteine ligase, modifier subunit 0.064
En1 engrailed 1 0.062
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.060
Gbp10 guanylate-binding protein 10 0.059
Usp2 ubiquitin specific peptidase 2 0.059
Fgfr1 fibroblast growth factor receptor 1 0.058
Rara retinoic acid receptor, alpha 0.057
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.056
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.053
Brca2 breast cancer 2 0.053
Rnf2 ring finger protein 2 0.053
Foxm1 forkhead box M1 0.053
Fbxl3 F-box and leucine-rich repeat protein 3 0.053
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.052
Ncoa3 nuclear receptor coactivator 3 0.052
Lrp6 low density lipoprotein receptor-related protein 6 0.052
Pycard PYD and CARD domain containing 0.051
Banf1 barrier to autointegration factor 1 0.051
Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.050
Stk4 serine/threonine kinase 4 0.050
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.049
Pten phosphatase and tensin homolog 0.048
Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.048
Casp1 caspase 1 0.048
Diablo diablo homolog (Drosophila) 0.048
Ptrf polymerase I and transcript release factor 0.047
Traf2 TNF receptor-associated factor 2 0.047
Eif2c1 eukaryotic translation initiation factor 2C, 1 0.047
Sox9 SRY-box containing gene 9 0.046
Trim21 tripartite motif-containing 21 0.046
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.046
Fgf8 fibroblast growth factor 8 0.046
Kdm2b lysine (K)-specific demethylase 2B 0.046
Ptch1 patched homolog 1 0.046
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.046
Trim25 tripartite motif-containing 25 0.045
Rarg retinoic acid receptor, gamma 0.045
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.045
Rbl2 retinoblastoma-like 2 0.045
Parp9 poly (ADP-ribose) polymerase family, member 9 0.045
Rel reticuloendotheliosis oncogene 0.044
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Rattus norvegicus
Name Description Probability Func Analog Organism