The network for 'protein deacylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein deacylation

The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.

Name Description Probability Func Analog Organism
SNT1 Snt1p 0.961
HDA2 Hda2p 0.940
SIN3 Sin3p 0.924
HOS4 Hos4p 0.892
HOS2 Hos2p 0.882
SIF2 Sif2p 0.818
SET3 Set3p 0.807
RCO1 Rco1p 0.802
HST1 Hst1p 0.724
UME1 Ume1p 0.652
CTI6 Cti6p 0.629
HDA3 Hda3p 0.399
SET2 Set2p 0.359
HDA1 Hda1p 0.322
CPR1 Cpr1p 0.280
SDS3 Sds3p 0.269
YML079W hypothetical protein 0.242
IRC8 Irc8p 0.196
ZDS1 Zds1p 0.165
RPD3 Rpd3p 0.100
CNB1 Cnb1p 0.091
YCL021W-A hypothetical protein 0.078
CAM1 Cam1p 0.074
GZF3 Gzf3p 0.072
CPR5 Cpr5p 0.071
IZH4 Izh4p 0.070
UME6 Ume6p 0.069
ASH1 Ash1p 0.068
YTA7 Yta7p 0.064
AMD1 Amd1p 0.061
PRI1 Pri1p 0.056
PCL9 Pcl9p 0.049
TOF2 Tof2p 0.048
CDC4 Cdc4p 0.047
YBR138C hypothetical protein 0.043
COF1 Cof1p 0.037
MSI1 Msi1p 0.037
SPL2 Spl2p 0.036
SET1 Set1p 0.036
SRD1 Srd1p 0.036
BDF1 Bdf1p 0.036
ACE2 Ace2p 0.035
YPL014W hypothetical protein 0.035
OPT2 Opt2p 0.034
PHO23 Pho23p 0.033
YLR264C-A hypothetical protein 0.033
YLR162W hypothetical protein 0.032
BCH2 Bch2p 0.032
HHT1 Hht1p 0.031
RXT3 Rxt3p 0.031
LEU2 Leu2p 0.031
NDD1 Ndd1p 0.030
YLR143W hypothetical protein 0.029
CMD1 Cmd1p 0.029
YBL029W hypothetical protein 0.029
RRN5 Rrn5p 0.029
SPT20 Spt20p 0.028
YJL181W hypothetical protein 0.028
SUM1 Sum1p 0.028
WWM1 Wwm1p 0.028
YOL038C-A hypothetical protein 0.027
MSH3 Msh3p 0.027
EST2 Est2p 0.026
SKI2 Ski2p 0.026
IZH3 Izh3p 0.026
ARG8 Arg8p 0.025
ACP1 Acp1p 0.025
GAL7 Gal7p 0.025
ARP10 Arp10p 0.025
URA3 Ura3p 0.025
YJL107C hypothetical protein 0.025
SSK1 Ssk1p 0.024
DOT6 Dot6p 0.024
SIZ1 Siz1p 0.024
OPI1 Opi1p 0.024
MER1 Mer1p 0.024
FMP52 Fmp52p 0.024
FMT1 Fmt1p 0.024
AAT1 Aat1p 0.023
TAX4 Tax4p 0.023
ECM30 Ecm30p 0.022
SAP30 Sap30p 0.022
YAR068W hypothetical protein 0.021
YBR013C hypothetical protein 0.021
CUP1-1 Cup1-1p 0.021
MTR10 Mtr10p 0.020
TIP1 Tip1p 0.020
RAM2 Ram2p 0.020
RNR2 Rnr2p 0.020
EAF1 Eaf1p 0.020
YLR278C hypothetical protein 0.020
ZPS1 Zps1p 0.020
YIL151C hypothetical protein 0.020
YIR035C hypothetical protein 0.019
YLR042C hypothetical protein 0.019
CPD1 Cpd1p 0.019
HXT3 Hxt3p 0.019
INN1 Inn1p 0.019
SOR2 Sor2p 0.019
AQR1 Aqr1p 0.019
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pbx4 pre-B-cell leukemia transcription factor 4 0.024
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.020
rarga retinoic acid receptor gamma a 0.020
ptprsa protein tyrosine phosphatase, receptor type, s, a 0.020
hsp47 heat shock protein 47 0.020
rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.020
mef2d myocyte enhancer factor 2d 0.019
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.018
osr1 odd-skipped related 1 (Drosophila) 0.017
mib mind bomb 0.017
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.016
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.016
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.016
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.016
axin2 axin 2 (conductin, axil) 0.016
tfe3a transcription factor binding to IGHM enhancer 3a 0.016
nova2 neuro-oncological ventral antigen 2 0.015
pou5f1 POU domain, class 5, transcription factor 1 0.015
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.015
tcf12 transcription factor 12 0.015
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.015
boc brother of CDO 0.014
cart1 cartilage paired-class homeoprotein 1 0.014
nphs1l nephrosis 1, congenital, Finnish type (nephrin)-like 0.014
st3gal5l ST3 beta-galactoside alpha-2,3-sialyltransferase 5, like 0.014
wtip Wilms tumor 1 interacting protein 0.013
btg1 B-cell translocation gene 1 0.013
ctnnb1 catenin (cadherin-associated protein), beta 1 0.013
hspd1 heat shock 60kD protein 1 (chaperonin) 0.013
ptpra protein tyrosine phosphatase, receptor type, A 0.013
pak2a p21 (CDKN1A)-activated kinase 2a 0.013
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.013
si:ch211-212m21.5 si:ch211-212m21.5 0.013
dab2ip DAB2 interacting protein 0.012
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.012
fxr2 fragile X mental retardation, autosomal homolog 2 0.012
foxi2 forkhead box I2 0.012
sephs1 selenophosphate synthetase 1 0.012
zgc:114140 zgc:114140 0.012
stxbp3 syntaxin binding protein 3 0.012
fas Fas (TNF receptor superfamily, member 6) 0.012
wt1b wilms tumor 1b 0.012
elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.012
dcun1d2 DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) 0.012
acss2 acyl-CoA synthetase short-chain family member 2 0.012
slit2 slit (Drosophila) homolog 2 0.012
ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1 0.011
smc3 structural maintenance of chromosomes 3 0.011
zgc:158605 zgc:158605 0.011
wdr82 WD repeat domain containing 82 0.011
foxa3 forkhead box A3 0.011
seh1l SEH1-like (S. cerevisiae) 0.011
zgc:55701 zgc:55701 0.011
h3f3a H3 histone, family 3A 0.011
pspc1 paraspeckle component 1 0.011
lamc1 laminin, gamma 1 0.011
cry1a cryptochrome 1a 0.011
ssbp3b single stranded DNA binding protein 3b 0.011
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.011
hspa9 heat shock protein 9 0.011
zgc:158604 zgc:158604 0.011
ubr7 ubiquitin protein ligase E3 component n-recognin 7 0.011
rcc2 regulator of chromosome condensation 2 0.010
zgc:158409 zgc:158409 0.010
dram2 DNA-damage regulated autophagy modulator 2 0.010
wu:fv91b12 wu:fv91b12 0.010
mknk2b MAP kinase-interacting serine/threonine kinase 2b 0.010
sfrs3b splicing factor, arginine/serine-rich 3b 0.010
zgc:77155 zgc:77155 0.010
ier5l immediate early response 5-like 0.010
phf2 PHD finger protein 2 0.010
hoxd13a homeo box D13a 0.010
dync1h1 dynein, cytoplasmic 1, heavy chain 1 0.010
supt3h suppressor of Ty 3 homolog (S. cerevisiae) 0.010
zgc:63587 zgc:63587 0.010
kirrelb kin of IRRE like b 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
CtBP C-terminal Binding Protein 0.022
Snr1 Snf5-related 1 0.018
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Homo sapiens
Name Description Probability Func Analog Organism
HDAC1 histone deacetylase 1 0.995
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.995
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.989
MAPK14 mitogen-activated protein kinase 14 0.972
NCOR2 nuclear receptor corepressor 2 0.966
SMAD4 SMAD family member 4 0.959
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.941
RB1 retinoblastoma 1 0.939
TGIF1 TGFB-induced factor homeobox 1 0.914
HDAC2 histone deacetylase 2 0.903
KDM1A lysine (K)-specific demethylase 1A 0.900
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.820
NCOR1 nuclear receptor corepressor 1 0.807
NRP1 neuropilin 1 0.779
JUN jun proto-oncogene 0.753
CREBBP CREB binding protein 0.733
VEGFA vascular endothelial growth factor A 0.723
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.703
MRFAP1 Morf4 family associated protein 1 0.676
HDAC3 histone deacetylase 3 0.661
ATF2 activating transcription factor 2 0.660
EP300 E1A binding protein p300 0.629
MTA3 metastasis associated 1 family, member 3 0.620
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.561
MAP2K4 mitogen-activated protein kinase kinase 4 0.514
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.500
HDAC4 histone deacetylase 4 0.499
IRF2BP1 interferon regulatory factor 2 binding protein 1 0.437
CHD4 chromodomain helicase DNA binding protein 4 0.408
SIRT1 sirtuin 1 0.346
DCAF7 DDB1 and CUL4 associated factor 7 0.333
HIPK2 homeodomain interacting protein kinase 2 0.331
ENG endoglin 0.307
ESR1 estrogen receptor 1 0.306
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.270
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.267
HDAC6 histone deacetylase 6 0.260
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.254
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.242
MORF4L1 mortality factor 4 like 1 0.230
MORF4L2 mortality factor 4 like 2 0.227
BRMS1 breast cancer metastasis suppressor 1 0.220
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.218
CUX1 cut-like homeobox 1 0.211
MTA1 metastasis associated 1 0.210
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.194
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.189
RCOR1 REST corepressor 1 0.186
HDAC7 histone deacetylase 7 0.168
RBBP4 retinoblastoma binding protein 4 0.166
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.165
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.156
HDAC5 histone deacetylase 5 0.153
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.151
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.151
MEF2C myocyte enhancer factor 2C 0.148
ADRBK1 adrenergic, beta, receptor kinase 1 0.121
SIRT3 sirtuin 3 0.121
CTBP1 C-terminal binding protein 1 0.119
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.118
ATF3 activating transcription factor 3 0.107
RUNX1 runt-related transcription factor 1 0.105
MECP2 methyl CpG binding protein 2 (Rett syndrome) 0.100
ARRB1 arrestin, beta 1 0.099
PGF placental growth factor 0.095
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.085
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.082
STAG2 stromal antigen 2 0.080
KIAA0182 KIAA0182 0.077
TSC22D1 TSC22 domain family, member 1 0.072
CHD3 chromodomain helicase DNA binding protein 3 0.072
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.071
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.071
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.071
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.070
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.066
C16orf70 chromosome 16 open reading frame 70 0.066
PDGFC platelet derived growth factor C 0.063
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.061
CUL7 cullin 7 0.060
PHF21A PHD finger protein 21A 0.059
SETD7 SET domain containing (lysine methyltransferase) 7 0.058
AHR aryl hydrocarbon receptor 0.057
CPNE6 copine VI (neuronal) 0.054
THRAP3 thyroid hormone receptor associated protein 3 0.054
TOP1 topoisomerase (DNA) I 0.053
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.053
MAPK3 mitogen-activated protein kinase 3 0.053
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.052
PML promyelocytic leukemia 0.051
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.050
MED15 mediator complex subunit 15 0.050
TBL1X transducin (beta)-like 1X-linked 0.049
SIRT2 sirtuin 2 0.048
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.048
HDAC9 histone deacetylase 9 0.047
SS18 synovial sarcoma translocation, chromosome 18 0.046
HSPA1L heat shock 70kDa protein 1-like 0.046
ZNF217 zinc finger protein 217 0.045
MYST1 MYST histone acetyltransferase 1 0.044
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Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 0.962
Sin3a transcriptional regulator, SIN3A (yeast) 0.954
Hdac1 histone deacetylase 1 0.929
Cry2 cryptochrome 2 (photolyase-like) 0.876
Nanog Nanog homeobox 0.859
Mef2d myocyte enhancer factor 2D 0.859
Arid1a AT rich interactive domain 1A (SWI-like) 0.854
Sox2 SRY-box containing gene 2 0.657
Jun Jun oncogene 0.655
Kdm5b lysine (K)-specific demethylase 5B 0.653
Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.646
Suds3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.545
Skil SKI-like 0.434
Sall4 sal-like 4 (Drosophila) 0.425
Pou5f1 POU domain, class 5, transcription factor 1 0.399
Vasp vasodilator-stimulated phosphoprotein 0.377
Pten phosphatase and tensin homolog 0.376
Tcfcp2l1 transcription factor CP2-like 1 0.235
Plin1 perilipin 1 0.190
Ncor1 nuclear receptor co-repressor 1 0.159
Egr1 early growth response 1 0.154
Yy1 YY1 transcription factor 0.154
Chd4 chromodomain helicase DNA binding protein 4 0.152
Tnf tumor necrosis factor 0.134
Arid1b AT rich interactive domain 1B (SWI-like) 0.124
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.121
Rxra retinoid X receptor alpha 0.117
Hdac2 histone deacetylase 2 0.114
Dusp1 dual specificity phosphatase 1 0.110
Csnk1e casein kinase 1, epsilon 0.108
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.106
Hdac5 histone deacetylase 5 0.101
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.096
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.095
Sin3b transcriptional regulator, SIN3B (yeast) 0.094
Rnf2 ring finger protein 2 0.089
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.086
Vcp valosin containing protein 0.084
Zeb1 zinc finger E-box binding homeobox 1 0.084
Srf serum response factor 0.082
Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.080
Pparg peroxisome proliferator activated receptor gamma 0.080
Sp1 trans-acting transcription factor 1 0.079
Mta2 metastasis-associated gene family, member 2 0.079
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.078
Mta1 metastasis associated 1 0.069
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 0.068
Brd1 bromodomain containing 1 0.068
Clock circadian locomotor output cycles kaput 0.067
Ncor2 nuclear receptor co-repressor 2 0.067
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.065
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.064
Stat3 signal transducer and activator of transcription 3 0.061
Ewsr1 Ewing sarcoma breakpoint region 1 0.057
Rnf44 ring finger protein 44 0.055
Tet1 tet oncogene 1 0.055
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.055
Rara retinoic acid receptor, alpha 0.055
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.054
Klf3 Kruppel-like factor 3 (basic) 0.051
Morf4l1 mortality factor 4 like 1 0.051
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.051
Wiz widely-interspaced zinc finger motifs 0.051
5430411K18Rik RIKEN cDNA 5430411K18 gene 0.049
Spry4 sprouty homolog 4 (Drosophila) 0.049
Rybp RING1 and YY1 binding protein 0.048
Cyr61 cysteine rich protein 61 0.048
Mef2c myocyte enhancer factor 2C 0.048
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.048
Csnk1g2 casein kinase 1, gamma 2 0.047
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.046
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.046
Evl Ena-vasodilator stimulated phosphoprotein 0.045
Casp8 caspase 8 0.045
Zfp36 zinc finger protein 36 0.044
Trp63 transformation related protein 63 0.044
Gatad2a GATA zinc finger domain containing 2A 0.043
Junb Jun-B oncogene 0.043
Daxx Fas death domain-associated protein 0.041
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.040
Tbl1xr1 transducin (beta)-like 1X-linked receptor 1 0.040
Rnf220 ring finger protein 220 0.040
Tgfbr1 transforming growth factor, beta receptor I 0.039
Pum1 pumilio 1 (Drosophila) 0.039
Gli2 GLI-Kruppel family member GLI2 0.039
Jarid2 jumonji, AT rich interactive domain 2 0.038
Sntb2 syntrophin, basic 2 0.038
Sall1 sal-like 1 (Drosophila) 0.037
Hcfc1 host cell factor C1 0.037
Usp2 ubiquitin specific peptidase 2 0.037
Thra thyroid hormone receptor alpha 0.036
Zbtb2 zinc finger and BTB domain containing 2 0.036
Esrrb estrogen related receptor, beta 0.036
Phf12 PHD finger protein 12 0.036
Nfil3 nuclear factor, interleukin 3, regulated 0.035
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.034
Grhl2 grainyhead-like 2 (Drosophila) 0.034
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.033
Rbbp4 retinoblastoma binding protein 4 0.033
Mdm2 transformed mouse 3T3 cell double minute 2 0.033
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psmb6 proteasome (prosome, macropain) subunit, beta type 6 0.015
Mrpl23 mitochondrial ribosomal protein L23 0.013
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.011
Cox5b cytochrome c oxidase subunit Vb 0.011
Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII 0.010