The network for 'glycerophospholipid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glycerophospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GPI8 Gpi8p 0.941
LAS21 Las21p 0.846
GPI17 Gpi17p 0.801
GAA1 Gaa1p 0.764
CDS1 Cds1p 0.741
GAB1 Gab1p 0.657
PSD1 Psd1p 0.607
MDM35 Mdm35p 0.599
TGL1 Tgl1p 0.578
PSD2 Psd2p 0.517
GPI16 Gpi16p 0.481
SPF1 Spf1p 0.466
EHT1 Eht1p 0.465
PER1 Per1p 0.405
PDR17 Pdr17p 0.371
MDM32 Mdm32p 0.354
YJR015W hypothetical protein 0.350
FAT1 Fat1p 0.349
GLO3 Glo3p 0.309
GWT1 Gwt1p 0.297
ARV1 Arv1p 0.285
GPI2 Gpi2p 0.276
INO2 Ino2p 0.249
RFT1 Rft1p 0.227
PLB2 Plb2p 0.223
SLC1 Slc1p 0.220
ROT2 Rot2p 0.201
CHO1 Cho1p 0.199
YGR205W hypothetical protein 0.196
YME1 Yme1p 0.192
SAM2 Sam2p 0.192
ITR1 Itr1p 0.184
IZH4 Izh4p 0.178
DIE2 Die2p 0.177
SPT14 Spt14p 0.176
CHO2 Cho2p 0.168
PFA4 Pfa4p 0.164
FAB1 Fab1p 0.163
MID1 Mid1p 0.150
TSC10 Tsc10p 0.145
UPS3 Ups3p 0.143
MDS3 Mds3p 0.143
SUR2 Sur2p 0.133
ASI2 Asi2p 0.132
CNA1 Cna1p 0.123
GLN3 Gln3p 0.123
CDC50 Cdc50p 0.121
ALG6 Alg6p 0.118
PTC7 Ptc7p 0.114
CTI6 Cti6p 0.113
YNL035C hypothetical protein 0.109
MON2 Mon2p 0.107
YOL107W hypothetical protein 0.106
RMR1 Rmr1p 0.106
YBR063C hypothetical protein 0.104
HTD2 Htd2p 0.104
GUP1 Gup1p 0.102
GPI13 Gpi13p 0.102
INO1 Ino1p 0.100
YGL082W hypothetical protein 0.099
GOT1 Got1p 0.099
YAP7 Yap7p 0.098
ELO1 Elo1p 0.098
OPI3 Opi3p 0.096
ERV29 Erv29p 0.096
YLR036C hypothetical protein 0.094
PFA5 Pfa5p 0.094
PMT3 Pmt3p 0.093
MCD4 Mcd4p 0.092
IMD2 Imd2p 0.092
AGE1 Age1p 0.091
NEM1 Nem1p 0.091
MOB2 Mob2p 0.091
FSH1 Fsh1p 0.091
MDM34 Mdm34p 0.090
ECM9 Ecm9p 0.090
RBD2 Rbd2p 0.089
GCS1 Gcs1p 0.087
YIM1 Yim1p 0.087
OPI1 Opi1p 0.086
YJU3 Yju3p 0.084
ERG5 Erg5p 0.084
SSL1 Ssl1p 0.082
MMF1 Mmf1p 0.080
YHR177W hypothetical protein 0.079
RXT3 Rxt3p 0.079
PRS2 Prs2p 0.078
YHB1 Yhb1p 0.074
RTS1 Rts1p 0.072
AVT4 Avt4p 0.071
SCT1 Sct1p 0.071
YNL108C hypothetical protein 0.070
RER2 Rer2p 0.070
GPI19 Gpi19p 0.068
SVP26 Svp26p 0.068
SFB3 Sfb3p 0.068
YDL133W hypothetical protein 0.067
TVP38 Tvp38p 0.065
YJR012C hypothetical protein 0.065
DGK1 Dgk1p 0.064
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
disp1 dispatched homolog 1 (Drosophila) 0.081
smyd2b SET and MYND domain containing 2b 0.057
nkx2.3 NK2 transcription factor related 3 0.057
fabp11a fatty acid binding protein 11a 0.047
pparg peroxisome proliferator activated receptor gamma 0.036
stc1l stanniocalcin 1, like 0.035
si:dkeyp-50f5.1 si:dkeyp-50f5.1 0.033
chm choroideremia 0.031
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.029
ak4 adenylate kinase 4 0.029
LOC569128 hypothetical protein LOC569128 0.023
mstna myostatin a 0.023
pdgfab platelet derived growth factor alpha b 0.023
azin1b antizyme inhibitor 1b 0.022
mitd1 MIT, microtubule interacting and transport, domain containing 1 0.022
katnb1 katanin p80 (WD repeat containing) subunit B 1 0.022
rnf180 ring finger protein 180 0.021
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.021
igfbp7 insulin-like growth factor binding protein 7 0.021
get4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.020
adipor1b adiponectin receptor 1b 0.020
sec11a SEC11 homolog A (S. cerevisiae) 0.019
ntn1a netrin 1a 0.019
smyd1a SET and MYND domain containing 1a 0.019
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.019
dmrt2b doublesex and mab-3 related transcription factor 2b 0.019
smoc2 secreted modular calcium binding protein 2 0.018
alp alkaline phosphatase 0.018
pvrl1a poliovirus receptor-related 1a 0.017
lamb1a laminin, beta 1a 0.017
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.017
ndfip1 Nedd4 family interacting protein 1 0.017
plp2 proteolipid protein 2 0.017
zgc:92806 zgc:92806 0.017
pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.017
phb2 prohibitin 2 0.017
pdgfaa platelet-derived growth factor alpha a 0.016
suclg2 succinate-CoA ligase, GDP-forming, beta subunit 0.016
brms1 breast cancer metastasis-suppressor 1 0.016
pgrmc1 progesterone receptor membrane component 1 0.016
rcbtb1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 0.016
rcn1 reticulocalbin 1, EF-hand calcium binding domain 0.016
bmp2a bone morphogenetic protein 2a 0.016
fa2h fatty acid 2-hydroxylase 0.016
use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.016
coq3 coenzyme Q3 homolog, methyltransferase (yeast) 0.015
ythdf3 YTH domain family 3 0.015
smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.015
si:dkey-228g21.4 si:dkey-228g21.4 0.015
nucb2b nucleobindin 2b 0.015
tollip toll interacting protein 0.015
nucb2a nucleobindin 2a 0.015
si:ch211-160j6.2 si:ch211-160j6.2 0.015
rdh10a retinol dehydrogenase 10a 0.015
ap3m1 adaptor-related protein complex 3, mu 1 subunit 0.015
zgc:110188 zgc:110188 0.015
egfra epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 0.015
emilin3a elastin microfibril interfacer 3a 0.015
pgam1b phosphoglycerate mutase 1b 0.015
dclk2 doublecortin-like kinase 2 0.015
emp2 epithelial membrane protein 2 0.014
ptmaa prothymosin, alpha a 0.014
kiss1 KiSS-1 metastasis-suppressor 0.014
ildr2 immunoglobulin-like domain containing receptor 2 0.014
pdia5 protein disulfide isomerase family A, member 5 0.014
vps26bl vacuolar protein sorting 26 homolog B, like 0.014
klfd Kruppel-like factor d 0.014
si:dkey-145p14.5 si:dkey-145p14.5 0.014
defbl3 defensin, beta-like 3 0.014
gdap1 ganglioside-induced differentiation-associated protein 1 0.014
fam8a1 family with sequence similarity 8, member A1 0.014
gyg1 glycogenin 1 0.014
bin2b bridging integrator 2b 0.014
ck2a2a casein kinase 2 alpha 2a 0.014
tyrp1b tyrosinase-related protein 1b 0.014
bmp2k BMP2 inducible kinase 0.013
dcun1d2 DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) 0.013
asph aspartate beta-hydroxylase 0.013
cratb carnitine O-acetyltransferase b 0.013
ptplad1 protein tyrosine phosphatase-like A domain containing 1 0.013
vac14 vac14 homolog (S. cerevisiae) 0.013
tmem135 transmembrane protein 135 0.013
ufsp2 ufm1-specific peptidase 2 0.013
zgc:158327 zgc:158327 0.013
zdhhc3 zinc finger, DHHC-type containing 3 0.013
zgc:92458 zgc:92458 0.013
si:ch211-239j15.4 si:ch211-239j15.4 0.013
znf277 zinc finger protein 277 0.013
minpp1b multiple inositol polyphosphate histidine phosphatase, 1b 0.012
efemp2 EGF-containing fibulin-like extracellular matrix protein 2 0.012
spam1 sperm adhesion molecule 1 0.012
antxr2a anthrax toxin receptor 2a 0.012
copg2 coatomer protein complex, subunit gamma 2 0.012
zgc:77112 zgc:77112 0.012
foxa1 forkhead box A1 0.012
acp5b acid phosphatase 5b, tartrate resistant 0.012
sesn3 sestrin 3 0.012
vps53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.012
homez homeodomain leucine zipper gene 0.012
ldha lactate dehydrogenase A4 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.997
FGFR1 fibroblast growth factor receptor 1 0.837
FGFR2 fibroblast growth factor receptor 2 0.813
GRB2 growth factor receptor-bound protein 2 0.642
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.532
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.480
MPDZ multiple PDZ domain protein 0.456
VEGFA vascular endothelial growth factor A 0.375
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.369
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.248
ALB albumin 0.246
IRS1 insulin receptor substrate 1 0.213
APOA1 apolipoprotein A-I 0.184
GPAA1 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) 0.179
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.152
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.143
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.143
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.137
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.114
NRP1 neuropilin 1 0.114
A2M alpha-2-macroglobulin 0.103
HP haptoglobin 0.098
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.083
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.081
CHMP2B chromatin modifying protein 2B 0.075
SYK spleen tyrosine kinase 0.072
NOS1 nitric oxide synthase 1 (neuronal) 0.068
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.067
PLCG1 phospholipase C, gamma 1 0.063
CMIP c-Maf-inducing protein 0.053
APOC1 apolipoprotein C-I 0.053
APOC3 apolipoprotein C-III 0.046
UVRAG UV radiation resistance associated gene 0.045
CD63 CD63 molecule 0.044
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.043
SH3BP2 SH3-domain binding protein 2 0.042
BLNK B-cell linker 0.041
CUTA cutA divalent cation tolerance homolog (E. coli) 0.040
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.039
PGF placental growth factor 0.038
SOS1 son of sevenless homolog 1 (Drosophila) 0.038
GAB1 GRB2-associated binding protein 1 0.038
BECN1 beclin 1, autophagy related 0.036
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.035
LCAT lecithin-cholesterol acyltransferase 0.035
FGF10 fibroblast growth factor 10 0.034
EGFR epidermal growth factor receptor 0.031
AXL AXL receptor tyrosine kinase 0.031
SPAG9 sperm associated antigen 9 0.031
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.030
GADD45A growth arrest and DNA-damage-inducible, alpha 0.029
SAR1B SAR1 homolog B (S. cerevisiae) 0.029
FGF7 fibroblast growth factor 7 0.029
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.028
FGF1 fibroblast growth factor 1 (acidic) 0.028
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.028
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.027
SLMO2 slowmo homolog 2 (Drosophila) 0.027
MDFI MyoD family inhibitor 0.026
C17orf28 chromosome 17 open reading frame 28 0.026
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 0.026
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.026
SORBS1 sorbin and SH3 domain containing 1 0.026
SORBS3 sorbin and SH3 domain containing 3 0.026
NME4 non-metastatic cells 4, protein expressed in 0.026
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.026
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.025
APOC2 apolipoprotein C-II 0.025
TLR3 toll-like receptor 3 0.024
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.024
GRB7 growth factor receptor-bound protein 7 0.024
PTPRB protein tyrosine phosphatase, receptor type, B 0.024
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.024
INO80B INO80 complex subunit B 0.024
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.024
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.023
GAB2 GRB2-associated binding protein 2 0.023
DCTN1 dynactin 1 0.023
TSPAN4 tetraspanin 4 0.023
GRB10 growth factor receptor-bound protein 10 0.022
C6orf211 chromosome 6 open reading frame 211 0.022
PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide 0.021
FGA fibrinogen alpha chain 0.021
VAV2 vav 2 guanine nucleotide exchange factor 0.021
IPO11 importin 11 0.021
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 0.021
GMFB glia maturation factor, beta 0.020
LMF2 lipase maturation factor 2 0.020
TMEM41B transmembrane protein 41B 0.020
SH2B1 SH2B adaptor protein 1 0.020
VAV3 vav 3 guanine nucleotide exchange factor 0.019
CD28 CD28 molecule 0.019
APOA2 apolipoprotein A-II 0.019
ERRFI1 ERBB receptor feedback inhibitor 1 0.019
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.019
LIN7C lin-7 homolog C (C. elegans) 0.019
SSTR3 somatostatin receptor 3 0.018
WDTC1 WD and tetratricopeptide repeats 1 0.018
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.018
TTR transthyretin 0.018
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Mus musculus
Name Description Probability Func Analog Organism
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.673
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.667
Pik3cb phosphatidylinositol 3-kinase, catalytic, beta polypeptide 0.618
Alox5ap arachidonate 5-lipoxygenase activating protein 0.590
Pten phosphatase and tensin homolog 0.266
Pik3r3 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) 0.201
Blnk B-cell linker 0.194
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.187
Cbl Casitas B-lineage lymphoma 0.177
Gab1 growth factor receptor bound protein 2-associated protein 1 0.171
Btk Bruton agammaglobulinemia tyrosine kinase 0.162
Pdlim4 PDZ and LIM domain 4 0.161
Irs1 insulin receptor substrate 1 0.152
Tmem38b transmembrane protein 38B 0.142
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.126
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.124
Parvg parvin, gamma 0.120
Cd40 CD40 antigen 0.112
Mta1 metastasis associated 1 0.096
Kpna2 karyopherin (importin) alpha 2 0.093
Ep300 E1A binding protein p300 0.091
Inpp5d inositol polyphosphate-5-phosphatase D 0.088
Notch2 Notch gene homolog 2 (Drosophila) 0.086
Nsun2 NOL1/NOP2/Sun domain family member 2 0.085
Pdgfc platelet-derived growth factor, C polypeptide 0.082
Lig4 ligase IV, DNA, ATP-dependent 0.074
Ipo5 importin 5 0.071
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.071
Lmf1 lipase maturation factor 1 0.070
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.069
Becn1 beclin 1, autophagy related 0.068
Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 0.067
Lpl lipoprotein lipase 0.065
Fyn Fyn proto-oncogene 0.064
Orai1 ORAI calcium release-activated calcium modulator 1 0.064
Rhbdf1 rhomboid family 1 (Drosophila) 0.063
Nbn nibrin 0.060
Phc2 polyhomeotic-like 2 (Drosophila) 0.059
Pcsk1 proprotein convertase subtilisin/kexin type 1 0.059
Tcrd T-cell receptor delta chain 0.058
Pik3r2 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) 0.057
Dsc3 desmocollin 3 0.055
Sh3d19 SH3 domain protein D19 0.053
Hook2 hook homolog 2 (Drosophila) 0.053
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.052
Cd36 CD36 antigen 0.052
Klk6 kallikrein related-peptidase 6 0.050
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.050
Bcl6 B-cell leukemia/lymphoma 6 0.049
Tmem98 transmembrane protein 98 0.048
Bsg basigin 0.048
Plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.048
Rab34 RAB34, member of RAS oncogene family 0.048
Mag myelin-associated glycoprotein 0.045
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.045
Rbp2 retinol binding protein 2, cellular 0.045
Apoe apolipoprotein E 0.044
Dok1 docking protein 1 0.044
Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 0.043
Fcgr2b Fc receptor, IgG, low affinity IIb 0.043
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.043
Trip6 thyroid hormone receptor interactor 6 0.043
Sorbs3 sorbin and SH3 domain containing 3 0.043
Stra6 stimulated by retinoic acid gene 6 0.041
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.041
Fbp2 fructose bisphosphatase 2 0.041
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.041
5730494N06Rik RIKEN cDNA 5730494N06 gene 0.040
3110056O03Rik RIKEN cDNA 3110056O03 gene 0.039
Ttr transthyretin 0.039
Padi2 peptidyl arginine deiminase, type II 0.039
Apob apolipoprotein B 0.039
Kifc3 kinesin family member C3 0.038
Lgals2 lectin, galactose-binding, soluble 2 0.038
Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.038
Padi4 peptidyl arginine deiminase, type IV 0.038
Dok3 docking protein 3 0.037
Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) 0.036
Flna filamin, alpha 0.036
Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 0.035
Dnm1 dynamin 1 0.035
Prkcd protein kinase C, delta 0.035
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.035
Gad2 glutamic acid decarboxylase 2 0.035
Sod2 superoxide dismutase 2, mitochondrial 0.034
Tcap titin-cap 0.034
Lasp1 LIM and SH3 protein 1 0.033
Dram2 VDNA-damage regulated autophagy modulator 2 0.033
Tgfbr1 transforming growth factor, beta receptor I 0.033
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.032
Tcf15 transcription factor 15 0.032
Gjb6 gap junction protein, beta 6 0.032
Sar1b SAR1 gene homolog B (S. cerevisiae) 0.032
Fam73b family with sequence similarity 73, member B 0.031
Dok2 docking protein 2 0.031
Pdcd6ip programmed cell death 6 interacting protein 0.031
Igh immunoglobulin heavy chain complex 0.030
Dnajb5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.030
Phlda3 pleckstrin homology-like domain, family A, member 3 0.030
Anapc7 anaphase promoting complex subunit 7 0.030
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Rattus norvegicus
Name Description Probability Func Analog Organism
Irs1 insulin receptor substrate 1 0.015
Alas2 aminolevulinate, delta-, synthase 2 0.011
Hba-a2 hemoglobin alpha, adult chain 2 0.011
Padi3 peptidyl arginine deiminase, type III 0.011
Phkg1 phosphorylase kinase, gamma 1 0.011
Man1a2 mannosidase, alpha, class 1A, member 2 0.011
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.010