The network for 'chromosome segregation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromosome segregation

The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

Danio rerio
Name Description Probability Func Analog Organism
sass6 spindle assembly 6 homolog (C. elegans) 0.880
ccnb1 cyclin B1 0.869
ccnb2 cyclin B2 0.460
ccna2 cyclin A2 0.444
piwil1 piwi-like 1 (Drosophila) 0.403
nuf2 NUF2, NDC80 kinetochore complex component, homolog 0.367
ncapg non-SMC condensin I complex, subunit G 0.334
pbx4 pre-B-cell leukemia transcription factor 4 0.318
ncapd2 non-SMC condensin I complex, subunit D2 0.296
plk1 polo-like kinase 1 (Drosophila) 0.275
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.253
zgc:110113 zgc:110113 0.210
lamc1 laminin, gamma 1 0.182
nanos3 nanos homolog 3 0.173
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.167
cdh1 cadherin 1, epithelial 0.164
ccne cyclin E 0.154
hoxa9b homeo box A9b 0.141
dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.138
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.138
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.136
smc4 structural maintenance of chromosomes 4 0.119
top2a topoisomerase (DNA) II alpha 0.119
smc1al structural maintenance of chromosomes 1A, like 0.117
zgc:56200 zgc:56200 0.115
tyms thymidylate synthase 0.113
si:ch211-244o22.2 si:ch211-244o22.2 0.103
hug HuG 0.100
hoxd9a homeo box D9a 0.095
si:ch211-69g19.2 si:ch211-69g19.2 0.092
msh6 mutS homolog 6 (E. coli) 0.090
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.088
melk maternal embryonic leucine zipper kinase 0.082
hoxa10b homeo box A10b 0.080
suv39h1b suppressor of variegation 3-9 homolog 1b 0.074
kif23 kinesin family member 23 0.070
nasp nuclear autoantigenic sperm protein (histone-binding) 0.069
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.069
wdr45 WD repeat domain 45 0.067
ube2i2 ubiquitin-conjugating enzyme E2I2 0.066
ahctf1 AT hook containing transcription factor 1 0.064
csnk1da casein kinase 1, delta a 0.064
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.063
zgc:65861 zgc:65861 0.062
chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.061
buc bucky ball 0.059
dtl denticleless homolog (Drosophila) 0.057
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.057
ctps CTP synthase 0.057
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.056
smc2 structural maintenance of chromosomes 2 0.055
rrm1 ribonucleotide reductase M1 polypeptide 0.054
asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.054
wu:fi04f09 wu:fi04f09 0.052
rpa2 replication protein A2 0.052
fn1 fibronectin 1 0.052
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.051
hoxd11a homeo box D11a 0.048
chaf1b chromatin assembly factor 1, subunit B 0.048
mybl2 myeloblastosis oncogene-like 2 0.047
racgap1 Rac GTPase-activating protein 1 0.046
cep55l centrosomal protein 55 like 0.046
aurka aurora kinase A 0.045
zgc:153910 zgc:153910 0.045
rbl1 retinoblastoma-like 1 (p107) 0.045
brca2 breast cancer 2, early onset 0.045
cdt1 chromatin licensing and DNA replication factor 1 0.045
hoxa13b homeo box A13b 0.045
hoxc9a homeo box C9a 0.044
srsf1a serine/arginine-rich splicing factor 1a 0.042
snx5 sorting nexin 5 0.042
aurkb aurora kinase B 0.040
im:7140452 im:7140452 0.040
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.039
prkci protein kinase C, iota 0.039
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.037
zgc:92775 zgc:92775 0.036
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.036
zgc:91910 zgc:91910 0.036
zgc:110380 zgc:110380 0.035
ipo9 importin 9 0.034
depdc1a DEP domain containing 1a 0.034
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.034
tuba7l tubulin, alpha 7 like 0.034
zgc:101661 zgc:101661 0.033
pbrm1l polybromo 1, like 0.032
csnk1g2a casein kinase 1, gamma 2a 0.031
dut dUTP pyrophosphatase 0.031
rtkn2 rhotekin 2 0.031
psmb4 proteasome (prosome, macropain) subunit, beta type, 4 0.031
rae1 RAE1 RNA export 1 homolog (S. pombe) 0.031
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.031
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.030
pole2 polymerase (DNA directed), epsilon 2 0.030
LOC100151531 zinc finger protein Gfi-1b-like 0.029
dnaja2l DnaJ (Hsp40) homolog, subfamily A, member 2, like 0.029
prc1b protein regulator of cytokinesis 1b 0.028
capza1a capping protein (actin filament) muscle Z-line, alpha 1a 0.028
fkbp1aa FK506 binding protein 1Aa 0.028
znf711 zinc finger protein 711 0.028
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
bub-1 Protein BUB-1 0.982
ndc-80 Protein NDC-80 0.910
gpr-1 Protein GPR-1 0.897
mcm-7 Protein MCM-7 0.870
bmk-1 Protein BMK-1 0.839
scc-1 Protein SCC-1 0.833
zyg-9 Protein ZYG-9 0.826
dcr-1 Protein DCR-1 0.814
rnr-1 Protein RNR-1 0.810
hcp-4 Protein HCP-4 0.785
knl-1 Protein KNL-1 0.784
klp-19 Protein KLP-19 0.773
retr-1 Protein RETR-1 0.771
CELE_C16C10.2 Protein C16C10.2 0.750
npp-1 Protein NPP-1 0.736
rga-3 Protein RGA-3 0.731
CELE_C24H12.5 Protein C24H12.5 0.720
spdl-1 Protein SPDL-1 0.704
fan-1 Protein FAN-1 0.701
sas-4 Protein SAS-4 0.683
rtel-1 Protein RTEL-1 0.677
ima-2 Protein IMA-2 0.672
hcp-1 Protein HCP-1 0.650
C01H6.9 Protein C01H6.9 0.649
brc-1 Protein BRC-1 0.641
R11A8.7 Protein R11A8.7 0.640
tag-232 Protein TAG-232 0.614
cyk-4 Protein CYK-4 0.612
aspm-1 Protein ASPM-1 0.590
CELE_F58A4.2 Protein F58A4.2 0.581
swsn-7 Protein SWSN-7 0.577
W03G9.2 Protein W03G9.2 0.564
csc-1 Protein CSC-1 0.557
klp-10 Protein KLP-10 0.557
mel-28 Protein MEL-28 0.548
thoc-2 Protein THOC-2 0.545
smc-4 Protein SMC-4 0.541
him-3 Protein HIM-3 0.539
Y49F6B.9 Protein Y49F6B.9 0.529
hmp-1 Protein HMP-1 0.528
plk-1 Protein PLK-1 0.526
rfc-4 Protein RFC-4 0.525
rbx-1 Protein RBX-1 0.515
klp-16 Protein KLP-16 0.511
F12F6.1 Protein F12F6.1 0.505
cec-9 Protein CEC-9 0.499
spk-1 Protein SPK-1 0.499
lst-3 Protein LST-3 0.495
isw-1 Protein ISW-1 0.495
ran-1 Protein RAN-1 0.494
CELE_C12D8.1 Protein C12D8.1 0.492
rod-1 Protein ROD-1 0.491
aipl-1 Protein AIPL-1 0.490
cpg-2 Protein CPG-2 0.489
T21B10.4 Protein T21B10.4 0.488
sas-5 Protein SAS-5 0.482
let-99 Protein LET-99 0.482
CELE_Y48B6A.1 Protein Y48B6A.1 0.476
gpr-2 Protein GPR-2 0.474
F08G5.1 Protein F08G5.1 0.470
ZK328.4 Protein ZK328.4 0.448
mom-2 Protein MOM-2 0.446
emb-27 Protein EMB-27 0.444
CELE_C39E9.12 Protein C39E9.12 0.440
T20B12.3 Protein T20B12.3 0.437
mau-2 Protein MAU-2 0.437
Y47D3A.29 Protein Y47D3A.29 0.435
smc-5 Protein SMC-5 0.435
clp-2 Protein CLP-2 0.434
him-6 Protein HIM-6 0.433
brd-1 Protein BRD-1 0.430
hpo-10 Protein HPO-10 0.429
T24D1.2 Protein T24D1.2 0.424
dsh-2 Protein DSH-2 0.423
F54C9.9 Protein F54C9.9 0.422
zim-1 Protein ZIM-1 0.417
mcm-3 Protein MCM-3 0.416
CELE_C25A1.4 Protein C25A1.4 0.416
mei-1 Protein MEI-1 0.412
ucr-2.3 Protein UCR-2.3 0.405
hke-4.1 Protein HKE-4.1 0.403
zyg-11 Protein ZYG-11 0.398
CELE_Y39E4B.2 Protein Y39E4B.2 0.395
lsy-22 Protein LSY-22 0.394
hcp-2 Protein HCP-2 0.392
zim-3 Protein ZIM-3 0.390
T09B4.5 Protein T09B4.5 0.386
lin-5 Protein LIN-5 0.385
CELE_C56A3.8 Protein C56A3.8 0.384
B0393.6 Protein B0393.6 0.380
skr-9 Protein SKR-9 0.379
hcp-6 Protein HCP-6 0.375
air-2 Protein AIR-2 0.374
rpa-1 Protein RPA-1 0.373
F10C2.4 Protein F10C2.4 0.365
dpl-1 Protein DPL-1 0.363
set-5 Protein SET-5 0.360
mep-1 Protein MEP-1 0.359
syx-4 Protein SYX-4 0.346
pgl-1 Protein PGL-1 0.345
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CycB Cyclin B 1.000
polo CG12306 gene product from transcript CG12306-RA 0.999
RfC4 Replication factor C subunit 4 0.999
asp abnormal spindle 0.999
nod no distributive disjunction 0.998
Pp1-87B Protein phosphatase 1 at 87B 0.995
ncd non-claret disjunctional 0.991
pav pavarotti 0.987
Cenp-C CG31258 gene product from transcript CG31258-RA 0.987
BubR1 Bub1-related kinase 0.984
mei-41 meiotic 41 0.983
Incenp Inner centromere protein 0.968
E(z) Enhancer of zeste 0.967
CycE Cyclin E 0.966
Klp10A CG1453 gene product from transcript CG1453-RA 0.960
pbl pebble 0.956
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.946
nej nejire 0.943
gwl greatwall 0.941
l(1)dd4 lethal (1) discs degenerate 4 0.932
Orc2 Origin recognition complex subunit 2 0.930
Su(var)205 Suppressor of variegation 205 0.926
asl asterless 0.920
dap dacapo 0.914
barr barren 0.898
Mcm10 Sensitized chromosome inheritance modifier 19 0.892
spn-A spindle A 0.886
CycA Cyclin A 0.882
Ndc80 CG9938 gene product from transcript CG9938-RA 0.880
pie pineapple eye 0.875
mod(mdg4) modifier of mdg4 0.867
smt3 CG4494 gene product from transcript CG4494-RA 0.848
nbs CG6754 gene product from transcript CG6754-RC 0.846
mus209 mutagen-sensitive 209 0.844
Mis12 CG18156 gene product from transcript CG18156-RA 0.840
alphaTub67C alpha-Tubulin at 67C 0.835
Cap-G CG34438 gene product from transcript CG34438-RF 0.828
Myb Myb oncogene-like 0.817
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.812
Klp3A Kinesin-like protein at 3A 0.810
spn-B spindle B 0.808
mei-9 meiotic 9 0.797
neb nebbish 0.796
rad50 CG6339 gene product from transcript CG6339-RD 0.790
Axn Axin 0.784
hay haywire 0.769
NiPp1 Nuclear inhibitor of Protein phosphatase 1 0.750
sub subito 0.750
Cks30A Cyclin-dependent kinase subunit 30A 0.747
dup double parked 0.743
Spc105R Spc105-related 0.726
Orc5 Origin recognition complex subunit 5 0.718
ctp cut up 0.712
ball ballchen 0.710
Rbf Retinoblastoma-family protein 0.709
RecQ4 CG7487 gene product from transcript CG7487-RA 0.709
Su(var)2-10 Suppressor of variegation 2-10 0.701
Dhc64C Dynein heavy chain 64C 0.699
SMC2 CG10212 gene product from transcript CG10212-RA 0.698
gammaTub37C gamma-Tubulin at 37C 0.697
BicD Bicaudal D 0.674
Iswi Imitation SWI 0.670
tum tumbleweed 0.661
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.661
tefu telomere fusion 0.654
l(2)dtl lethal-(2)-denticleless 0.654
dpa disc proliferation abnormal 0.630
cmet CENP-meta 0.622
spn-E spindle E 0.621
Cp190 Centrosomal protein 190kD 0.620
png pan gu 0.618
zwilch CG18729 gene product from transcript CG18729-RA 0.617
okr okra 0.607
mars CG17064 gene product from transcript CG17064-RB 0.592
Det Deterin 0.590
CycB3 Cyclin B3 0.585
SAK Sak kinase 0.583
Klp61F Kinesin-like protein at 61F 0.577
JIL-1 CG6297 gene product from transcript CG6297-RA 0.576
pim pimples 0.574
Sse Separase 0.564
mus304 mutagen-sensitive 304 0.549
stg string 0.521
SMC1 CG6057 gene product from transcript CG6057-RA 0.520
cid centromere identifier 0.507
Gap1 GTPase-activating protein 1 0.506
trbl tribbles 0.489
c(3)G crossover suppressor on 3 of Gowen 0.480
geminin CG3183 gene product from transcript CG3183-RA 0.476
ida imaginal discs arrested 0.476
Klp67A Kinesin-like protein at 67A 0.474
mrn marionette 0.472
Psn Presenilin 0.457
par-1 CG8201 gene product from transcript CG8201-RA 0.454
spn-D spindle D 0.432
stau staufen 0.429
ial IplI-aurora-like kinase 0.428
wisp wispy 0.424
mus312 mutagen-sensitive 312 0.419
Nuf2 CG8902 gene product from transcript CG8902-RA 0.414
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.998
RAD21 RAD21 homolog (S. pombe) 0.997
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.996
CDK2 cyclin-dependent kinase 2 0.989
BRCA1 breast cancer 1, early onset 0.989
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.985
NDC80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.982
SMC2 structural maintenance of chromosomes 2 0.982
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.981
SMC1A structural maintenance of chromosomes 1A 0.976
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.974
CBX5 chromobox homolog 5 0.968
CENPE centromere protein E, 312kDa 0.967
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.964
YY1 YY1 transcription factor 0.961
RBL1 retinoblastoma-like 1 (p107) 0.954
RB1 retinoblastoma 1 0.951
ANAPC4 anaphase promoting complex subunit 4 0.939
CCNB1 cyclin B1 0.931
RACGAP1 Rac GTPase activating protein 1 0.918
FBXO5 F-box protein 5 0.912
CDC23 cell division cycle 23 homolog (S. cerevisiae) 0.911
STAG1 stromal antigen 1 0.903
PRC1 protein regulator of cytokinesis 1 0.902
NCAPH non-SMC condensin I complex, subunit H 0.899
KIF2C kinesin family member 2C 0.894
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.887
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.882
WAPAL wings apart-like homolog (Drosophila) 0.877
NCAPG non-SMC condensin I complex, subunit G 0.875
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.873
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.858
KIF11 kinesin family member 11 0.857
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.855
ATM ataxia telangiectasia mutated 0.852
SGOL1 shugoshin-like 1 (S. pombe) 0.851
SMC3 structural maintenance of chromosomes 3 0.838
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.826
CCNA2 cyclin A2 0.808
SGOL2 shugoshin-like 2 (S. pombe) 0.797
SMC4 structural maintenance of chromosomes 4 0.796
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.791
TRIP13 thyroid hormone receptor interactor 13 0.767
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.763
MCM10 minichromosome maintenance complex component 10 0.760
ZWINT ZW10 interactor 0.760
MKI67 antigen identified by monoclonal antibody Ki-67 0.755
RFC3 replication factor C (activator 1) 3, 38kDa 0.749
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.746
NSL1 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) 0.737
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.733
STAG2 stromal antigen 2 0.716
CENPF centromere protein F, 350/400kDa (mitosin) 0.714
PLK1 polo-like kinase 1 0.712
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.703
PDS5B PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.696
NCAPG2 non-SMC condensin II complex, subunit G2 0.690
RBBP8 retinoblastoma binding protein 8 0.685
RFC1 replication factor C (activator 1) 1, 145kDa 0.671
ANLN anillin, actin binding protein 0.667
CASC5 cancer susceptibility candidate 5 0.657
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.650
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.645
KIF23 kinesin family member 23 0.639
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.637
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.636
CBX1 chromobox homolog 1 0.632
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.619
PDS5A PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) 0.612
SFN stratifin 0.611
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.609
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.604
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.598
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.585
NBN nibrin 0.569
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.566
CEP55 centrosomal protein 55kDa 0.559
GSK3B glycogen synthase kinase 3 beta 0.546
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 0.539
RAD50 RAD50 homolog (S. cerevisiae) 0.533
TTK TTK protein kinase 0.533
KIF18A kinesin family member 18A 0.522
NUF2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.518
TOPBP1 topoisomerase (DNA) II binding protein 1 0.514
MSH6 mutS homolog 6 (E. coli) 0.514
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.511
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.509
AURKB aurora kinase B 0.509
MCM5 minichromosome maintenance complex component 5 0.503
PLK4 polo-like kinase 4 0.498
FOXM1 forkhead box M1 0.490
TACC3 transforming, acidic coiled-coil containing protein 3 0.471
SMC6 structural maintenance of chromosomes 6 0.465
ORC1 origin recognition complex, subunit 1 0.462
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.458
SRPK1 SRSF protein kinase 1 0.457
BRCA2 breast cancer 2, early onset 0.457
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.454
DSN1 DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) 0.450
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Cdk1 cyclin-dependent kinase 1 0.993
Ccnb1 cyclin B1 0.987
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.980
Ccna2 cyclin A2 0.937
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.936
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.932
Ccne1 cyclin E1 0.924
Kif22 kinesin family member 22 0.924
Brca1 breast cancer 1 0.913
Cdca8 cell division cycle associated 8 0.892
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.887
Aurkb aurora kinase B 0.880
Ccnb2 cyclin B2 0.866
Incenp inner centromere protein 0.865
Brca2 breast cancer 2 0.856
Plk1 polo-like kinase 1 (Drosophila) 0.843
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.828
Birc5 baculoviral IAP repeat-containing 5 0.806
Sgol1 shugoshin-like 1 (S. pombe) 0.783
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.782
Prc1 protein regulator of cytokinesis 1 0.775
Ccnf cyclin F 0.765
Rad51ap1 RAD51 associated protein 1 0.762
Cdca5 cell division cycle associated 5 0.755
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.754
Kif20a kinesin family member 20A 0.729
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.729
Mybl2 myeloblastosis oncogene-like 2 0.726
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.694
Cenpa centromere protein A 0.639
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.636
Gsk3b glycogen synthase kinase 3 beta 0.630
Racgap1 Rac GTPase-activating protein 1 0.623
Kif11 kinesin family member 11 0.614
Ckap2 cytoskeleton associated protein 2 0.610
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.586
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.572
Spag5 sperm associated antigen 5 0.571
Plk4 polo-like kinase 4 (Drosophila) 0.565
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.564
Mdm2 transformed mouse 3T3 cell double minute 2 0.561
Cdk2 cyclin-dependent kinase 2 0.558
Melk maternal embryonic leucine zipper kinase 0.545
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.534
Lrrk2 leucine-rich repeat kinase 2 0.510
C330027C09Rik RIKEN cDNA C330027C09 gene 0.508
Trim59 tripartite motif-containing 59 0.493
Stil Scl/Tal1 interrupting locus 0.490
Rbl1 retinoblastoma-like 1 (p107) 0.489
Kif4 kinesin family member 4 0.486
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.484
Cenpe centromere protein E 0.475
Trp53 transformation related protein 53 0.472
Ncaph non-SMC condensin I complex, subunit H 0.459
Ube2c ubiquitin-conjugating enzyme E2C 0.447
Aurka aurora kinase A 0.439
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.434
Kif2c kinesin family member 2C 0.425
Gmnn geminin 0.415
Cenpn centromere protein N 0.413
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.408
Hoxd10 homeobox D10 0.405
Gtse1 G two S phase expressed protein 1 0.400
Impad1 inositol monophosphatase domain containing 1 0.398
Kif5b kinesin family member 5B 0.394
Cdt1 chromatin licensing and DNA replication factor 1 0.385
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.385
Ccdc99 coiled-coil domain containing 99 0.384
E2f1 E2F transcription factor 1 0.380
Tmpo thymopoietin 0.377
Chek1 checkpoint kinase 1 homolog (S. pombe) 0.372
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.370
Usp9x ubiquitin specific peptidase 9, X chromosome 0.366
Pds5a PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) 0.358
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.356
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.353
Hoxa10 homeobox A10 0.330
Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.328
Ctnnb1 catenin (cadherin associated protein), beta 1 0.320
Lig1 ligase I, DNA, ATP-dependent 0.309
Smc2 structural maintenance of chromosomes 2 0.308
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.308
Haus6 HAUS augmin-like complex, subunit 6 0.306
Cops2 COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) 0.286
Stag1 stromal antigen 1 0.281
Smc1a structural maintenance of chromosomes 1A 0.278
Smc4 structural maintenance of chromosomes 4 0.272
Rrm2 ribonucleotide reductase M2 0.270
Shcbp1 Shc SH2-domain binding protein 1 0.270
Ect2 ect2 oncogene 0.267
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.257
Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) 0.253
D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, expressed 0.250
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.247
Sept7 septin 7 0.245
Ttk Ttk protein kinase 0.242
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.235
Vapa vesicle-associated membrane protein, associated protein A 0.232
Recql RecQ protein-like 0.229
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.228
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.777
Ccnb1 cyclin B1 0.681
Ube2c ubiquitin-conjugating enzyme E2C 0.664
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.510
Racgap1 Rac GTPase-activating protein 1 0.484
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.484
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.434
Kif2c kinesin family member 2C 0.420
Pttg1 pituitary tumor-transforming 1 0.398
Traf4af1 TRAF4 associated factor 1 0.377
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.329
Timeless timeless homolog (Drosophila) 0.318
Foxm1 forkhead box M1 0.302
Cdk1 cyclin-dependent kinase 1 0.280
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.275
Spag5 sperm associated antigen 5 0.247
Cks2 CDC28 protein kinase regulatory subunit 2 0.235
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.234
Kif22 kinesin family member 22 0.221
Cdca3 cell division cycle associated 3 0.220
Stip1 stress-induced phosphoprotein 1 0.218
Nap1l1 nucleosome assembly protein 1-like 1 0.215
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.210
Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.209
Exoc5 exocyst complex component 5 0.207
Txnrd1 thioredoxin reductase 1 0.206
Troap trophinin associated protein 0.194
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.191
Kifc1 kinesin family member C1 0.183
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.173
Ccnb2 cyclin B2 0.170
Vcp valosin-containing protein 0.169
LOC689399 hypothetical protein LOC689399 0.160
Arpc5 actin related protein 2/3 complex, subunit 5 0.151
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.148
Mcm7 minichromosome maintenance complex component 7 0.146
Scaf1 SR-related CTD-associated factor 1 0.138
Hdlbp high density lipoprotein binding protein 0.137
Espl1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.133
Mki67 antigen identified by monoclonal antibody Ki-67 0.131
Plk1 polo-like kinase 1 (Drosophila) 0.126
Cdkn3 cyclin-dependent kinase inhibitor 3 0.124
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.123
Mcm5 minichromosome maintenance complex component 5 0.121
Cdca8 cell division cycle associated 8 0.121
Agfg1 ArfGAP with FG repeats 1 0.118
Rrm2 ribonucleotide reductase M2 0.117
Kpnb1 karyopherin (importin) beta 1 0.116
Hist1h1a histone cluster 1, H1a 0.114
Depdc1 DEP domain containing 1 0.113
Ccne1 cyclin E1 0.112
LOC100310874 antisense RNA overlapping MCH 0.109
Wbp2 WW domain binding protein 2 0.104
Nckap1 NCK-associated protein 1 0.103
Caprin1 cell cycle associated protein 1 0.102
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.102
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.099
Snd1 staphylococcal nuclease and tudor domain containing 1 0.098
Cenpt centromere protein T 0.095
Pias2 protein inhibitor of activated STAT, 2 0.095
Cdca2 cell division cycle associated 2 0.092
Rab10 RAB10, member RAS oncogene family 0.092
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.090
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.089
Rbbp7 retinoblastoma binding protein 7 0.088
Arpc2 actin related protein 2/3 complex, subunit 2 0.088
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.087
Mcm6 minichromosome maintenance complex component 6 0.086
Rtn4 reticulon 4 0.085
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.084
Birc5 baculoviral IAP repeat-containing 5 0.083
Prc1 protein regulator of cytokinesis 1 0.082
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.081
Rpn2 ribophorin II 0.081
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.081
Taok1 TAO kinase 1 0.081
Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.080
Cdh1 cadherin 1 0.079
Zfr zinc finger RNA binding protein 0.078
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.077
Ncapd2 non-SMC condensin I complex, subunit D2 0.076
Eef2 eukaryotic translation elongation factor 2 0.076
Nusap1 nucleolar and spindle associated protein 1 0.075
Mtpn myotrophin 0.074
Fkbp4 FK506 binding protein 4 0.073
Myo1b myosin Ib 0.073
Tox4 TOX high mobility group box family member 4 0.072
Rpl22 ribosomal protein L22 0.072
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.071
Aurkb aurora kinase B 0.071
Ubl3 ubiquitin-like 3 0.071
Zfp364 zinc finger protein 364 0.070
Nrd1 nardilysin 1 0.070
Bard1 BRCA1 associated RING domain 1 0.069
Vipr1 vasoactive intestinal peptide receptor 1 0.067
Tpm3 tropomyosin 3, gamma 0.066
Lbr lamin B receptor 0.065
Arcn1 archain 1 0.064
Dapk3 death-associated protein kinase 3 0.064
Prkar1a protein kinase, cAMP-dependent, regulatory, type I, alpha 0.064
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
DSN1 Dsn1p 1.000
BIM1 Bim1p 0.997
SMC4 Smc4p 0.994
DAM1 Dam1p 0.992
TID3 Tid3p 0.991
SMC3 Smc3p 0.990
MAD1 Mad1p 0.989
ECO1 Eco1p 0.986
CBF2 Cbf2p 0.982
MPS1 Mps1p 0.979
CSM1 Csm1p 0.977
NSL1 Nsl1p 0.975
SPC105 Spc105p 0.975
STU2 Stu2p 0.973
SPC24 Spc24p 0.973
MTW1 Mtw1p 0.962
MCD1 Mcd1p 0.961
ASK1 Ask1p 0.961
CSE4 Cse4p 0.949
CTF3 Ctf3p 0.948
DOC1 Doc1p 0.934
MIF2 Mif2p 0.933
IML3 Iml3p 0.932
AME1 Ame1p 0.932
CHL4 Chl4p 0.928
RFC5 Rfc5p 0.928
SMC2 Smc2p 0.923
SGS1 Sgs1p 0.919
CDC27 Cdc27p 0.917
MCM21 Mcm21p 0.915
PPH21 Pph21p 0.910
CIN8 Cin8p 0.910
CSM3 Csm3p 0.908
SLI15 Sli15p 0.890
ZDS2 Zds2p 0.889
RDH54 Rdh54p 0.886
IPL1 Ipl1p 0.869
CDC23 Cdc23p 0.868
KAR3 Kar3p 0.864
MND2 Mnd2p 0.859
PDS5 Pds5p 0.859
BIR1 Bir1p 0.855
RAD54 Rad54p 0.852
CDC16 Cdc16p 0.850
DAD4 Dad4p 0.844
MCM22 Mcm22p 0.838
MAD2 Mad2p 0.837
CTF4 Ctf4p 0.829
RAD24 Rad24p 0.823
BUB3 Bub3p 0.819
SDS22 Sds22p 0.812
CDC20 Cdc20p 0.809
CNN1 Cnn1p 0.808
CDC26 Cdc26p 0.798
MCM16 Mcm16p 0.798
DUO1 Duo1p 0.792
SMC1 Smc1p 0.785
SPC19 Spc19p 0.780
DCC1 Dcc1p 0.779
CTF19 Ctf19p 0.777
BBC1 Bbc1p 0.740
SPT2 Spt2p 0.734
MMS21 Mms21p 0.727
SGV1 Sgv1p 0.706
NUF2 Nuf2p 0.705
SPC34 Spc34p 0.693
HSK3 Hsk3p 0.690
RFC2 Rfc2p 0.683
SAC6 Sac6p 0.679
DAD2 Dad2p 0.668
CDC28 Cdc28p 0.657
BUB1 Bub1p 0.656
SGO1 Sgo1p 0.652
SPC97 Spc97p 0.641
YPI1 Ypi1p 0.631
APC11 Apc11p 0.626
ARP9 Arp9p 0.617
RAD53 Rad53p 0.601
CTF18 Ctf18p 0.593
BRN1 Brn1p 0.587
RFC4 Rfc4p 0.582
SLX8 Slx8p 0.576
CHL1 Chl1p 0.574
CDC5 Cdc5p 0.553
SPC25 Spc25p 0.546
ORC1 Orc1p 0.527
RAD27 Rad27p 0.514
PDS1 Pds1p 0.506
SCC2 Scc2p 0.505
CDC7 Cdc7p 0.488
RAD52 Rad52p 0.484
POL3 Pol3p 0.481
SRS2 Srs2p 0.463
HRR25 Hrr25p 0.460
BRE1 Bre1p 0.454
OKP1 Okp1p 0.449
YCS4 Ycs4p 0.444
BNR1 Bnr1p 0.438
SCM3 Scm3p 0.436
PFS1 Pfs1p 0.436