The network for 'gtp metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gtp metabolic process

The chemical reactions and pathways involving GTP, guanosine triphosphate.

Danio rerio
Name Description Probability Func Analog Organism
gsna gelsolin a 0.638
pak2a p21 (CDKN1A)-activated kinase 2a 0.312
pvrl1b poliovirus receptor-related 1b 0.310
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.274
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.267
mcl1b myeloid cell leukemia sequence 1b 0.261
bida BH3 interacting domain death agonist 0.261
acvr1b activin A receptor, type IB 0.258
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.234
rab1a RAB1A, member RAS oncogene family 0.229
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.225
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.222
arf5 ADP-ribosylation factor 5 0.220
rab5aa RAB5A, member RAS oncogene family, a 0.217
nf1a neurofibromin 1a 0.212
wu:fc24e06 wu:fc24e06 0.210
cnn2 calponin 2 0.207
adrb2a adrenergic receptor, beta 2a 0.205
calcrla calcitonin receptor-like a 0.204
pob partial optokinetic response b 0.197
rtcd1 RNA terminal phosphate cyclase domain 1 0.196
msna moesin a 0.195
rhoaa ras homolog gene family, member Aa 0.190
arpc5a actin related protein 2/3 complex, subunit 5A 0.184
krt18 keratin 18 0.183
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.182
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.182
yap1 Yes-associated protein 1 0.179
esyt3 extended synaptotagmin-like protein 3 0.177
tm9sf2 transmembrane 9 superfamily member 2 0.176
si:ch211-232m7.1 si:ch211-232m7.1 0.175
eomesa eomesodermin homolog a 0.174
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.170
efna1b ephrin A1b 0.165
rras related RAS viral (r-ras) oncogene homolog 0.164
rab7 RAB7, member RAS oncogene family 0.161
zbtb4 zinc finger and BTB domain containing 4 0.161
dtnbp1a dystrobrevin binding protein 1a 0.160
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.157
optc opticin 0.153
cotl1 coactosin-like 1 (Dictyostelium) 0.151
atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide 0.151
lrrn1 leucine rich repeat neuronal 1 0.150
iqgap1 IQ motif containing GTPase activating protein 1 0.150
lingo1a leucine rich repeat and Ig domain containing 1a 0.147
mecp2 methyl CpG binding protein 2 0.147
dlg1 discs, large (Drosophila) homolog 1 0.146
gngt2a guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a 0.145
snx6 sorting nexin 6 0.145
zgc:92237 zgc:92237 0.144
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.144
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.142
si:ch1073-204j4.2 si:ch1073-204j4.2 0.138
rtn1a reticulon 1a 0.137
pdcd6 programmed cell death 6 0.136
emx2 empty spiracles homeobox 2 0.132
arpc5b actin related protein 2/3 complex, subunit 5B 0.131
alcamb activated leukocyte cell adhesion molecule b 0.130
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.129
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.129
pou3f2 POU class 3 homeobox 2 0.129
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.128
foxb1.1 forkhead box B1.1 0.125
lin7b lin-7 homolog B (C. elegans) 0.125
tmem59l transmembrane protein 59-like and transmembrane protein 59-like 0.124
sbf1 SET binding factor 1 0.122
psen1 presenilin 1 0.122
bzw1b basic leucine zipper and W2 domains 1b 0.121
zgc:77051 zgc:77051 0.120
mycbp2 MYC binding protein 2 0.120
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.120
zgc:64040 zgc:64040 0.120
copeb core promoter element binding protein 0.119
wu:fb71f10 wu:fb71f10 0.119
pparg peroxisome proliferator activated receptor gamma 0.117
polr1c polymerase (RNA) I polypeptide C 0.117
ndufs2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 0.114
st3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.114
bactin1 bactin1 0.113
cyt1 type I cytokeratin, enveloping layer 0.111
vps26bl vacuolar protein sorting 26 homolog B, like 0.111
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.110
ptprna protein tyrosine phosphatase, receptor type, Na 0.110
cdkl1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.110
lmo3 LIM domain only 3 0.110
mcl1a myeloid cell leukemia sequence 1a 0.109
nrarpb notch-regulated ankyrin repeat protein b 0.109
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.109
elovl4b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b 0.109
srpr signal recognition particle receptor (docking protein) 0.109
gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 0.108
sncgb synuclein, gamma b (breast cancer-specific protein 1) 0.107
fem1c fem-1 homolog c (C.elegans) 0.106
rhoab ras homolog gene family, member Ab 0.106
stmn4 stathmin-like 4 0.106
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.105
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.105
c10orf11 c10orf11 homolog (H. sapiens) 0.105
zgc:56272 zgc:56272 0.104
adrb3a adrenergic receptor, beta 3a 0.104
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.927
sem-5 Protein SEM-5 0.627
gpb-1 Protein GPB-1 0.475
etr-1 Protein ETR-1 0.423
lag-1 Protein LAG-1 0.339
pkg-1 Protein PKG-1 0.245
osm-5 Protein OSM-5 0.199
daf-19 Protein DAF-19 0.180
T23F11.1 Protein T23F11.1 0.155
tat-1 Protein TAT-1 0.153
csnk-1 Protein CSNK-1 0.147
snf-1 Protein SNF-1 0.137
dpm-1 Protein DPM-1 0.136
mig-2 Protein MIG-2 0.135
rab-5 Protein RAB-5 0.131
pat-3 Protein PAT-3 0.129
ykt-6 Protein YKT-6 0.119
sup-17 Protein SUP-17 0.108
unc-26 Protein UNC-26 0.106
unc-71 Protein UNC-71 0.101
let-60 Protein LET-60 0.101
ddr-2 Protein DDR-2 0.098
CELE_F47G4.4 Protein F47G4.4 0.093
dnj-27 Protein DNJ-27 0.090
ttx-1 Protein TTX-1 0.090
mtm-3 Protein MTM-3 0.087
eor-2 Protein EOR-2 0.085
egrh-1 Protein EGRH-1 0.084
lec-1 Protein LEC-1 0.084
plc-3 Protein PLC-3 0.082
rme-4 Protein RME-4 0.081
cmd-1 Protein CMD-1 0.081
gpr-1 Protein GPR-1 0.080
syp-1 Protein SYP-1 0.072
C05E11.3 Protein C05E11.3 0.072
cyld-1 Protein CYLD-1 0.071
che-13 Protein CHE-13 0.068
F22D3.2 Protein F22D3.2 0.067
ced-10 Protein CED-10 0.065
egl-18 Protein EGL-18 0.065
T23F2.2 Protein T23F2.2 0.064
sma-6 Protein SMA-6 0.063
F59F4.2 Protein F59F4.2 0.062
gras-1 Protein GRAS-1 0.062
lst-4 Protein LST-4 0.060
gei-8 Protein GEI-8 0.059
apg-1 Protein APG-1 0.057
zoo-1 Protein ZOO-1 0.055
itr-1 Protein ITR-1 0.055
klp-7 Protein KLP-7 0.054
tag-123 Protein TAG-123 0.054
C27H2.2 Protein C27H2.2 0.054
pkn-1 Protein PKN-1 0.053
aha-1 Protein AHA-1 0.053
T04F8.6 Protein T04F8.6 0.052
unc-108 Protein UNC-108 0.051
ina-1 Protein INA-1 0.051
F33G12.5 Protein F33G12.5 0.050
magi-1 Protein MAGI-1 0.048
T28B11.1 Protein T28B11.1 0.048
frm-7 Protein FRM-7 0.047
npp-7 Protein NPP-7 0.047
vab-10 Protein VAB-10 0.047
rps-2 Protein RPS-2 0.047
tag-335 Protein TAG-335 0.047
CELE_K08E7.6 Protein K08E7.6 0.046
cdk-1 Protein CDK-1 0.046
pqe-1 Protein PQE-1 0.046
atf-7 Protein ATF-7 0.045
vps-32.1 Protein VPS-32.1 0.044
ric-8 Protein RIC-8 0.044
stam-1 Protein STAM-1 0.044
chc-1 Protein CHC-1 0.043
panl-3 Protein PANL-3 0.043
fhod-1 Protein FHOD-1 0.043
Y50C1A.1 Protein Y50C1A.1 0.043
abts-1 Protein ABTS-1 0.043
let-607 Protein LET-607 0.043
R10E12.2 Protein R10E12.2 0.042
CELE_Y47G6A.18 Protein Y47G6A.18 0.042
unc-119 Protein UNC-119 0.042
ppm-1 Protein PPM-1 0.042
pdl-1 Protein PDL-1 0.042
mrck-1 Protein MRCK-1 0.041
act-3 Protein ACT-3 0.041
lir-1 Protein LIR-1 0.041
cutl-26 Protein CUTL-26 0.040
CELE_Y60A3A.9 Protein Y60A3A.9 0.040
tpxl-1 Protein TPXL-1 0.040
dpf-3 Protein DPF-3 0.039
zfp-1 Protein ZFP-1 0.039
CELE_Y53F4B.4 Protein Y53F4B.4 0.039
rgl-1 Protein RGL-1 0.038
eat-20 Protein EAT-20 0.038
smd-1 Protein SMD-1 0.038
gly-7 Protein GLY-7 0.038
unc-40 Protein UNC-40 0.038
cyk-4 Protein CYK-4 0.038
F07C6.4 Protein F07C6.4 0.038
hsr-9 Protein HSR-9 0.037
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
pod1 CG4532 gene product from transcript CG4532-RF 0.783
Rheb CG1081 gene product from transcript CG1081-RA 0.754
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.732
Rac1 CG2248 gene product from transcript CG2248-RA 0.710
Pkn Protein kinase related to protein kinase N 0.640
Rab7 Rab-protein 7 0.575
drk downstream of receptor kinase 0.549
rok Rho-kinase 0.508
Ced-12 CG5336 gene product from transcript CG5336-RA 0.486
trio CG18214 gene product from transcript CG18214-RA 0.446
Vps35 Vacuolar protein sorting 35 0.429
Sos Son of sevenless 0.387
Galpha49B G protein alpha49B 0.381
Stat92E Signal-transducer and activator of transcription protein at 92E 0.375
rl rolled 0.373
mbc myoblast city 0.345
Rho1 CG8416 gene product from transcript CG8416-RB 0.334
Alk CG8250 gene product from transcript CG8250-RA 0.315
cenG1A centaurin gamma 1A 0.301
Rab2 Rab-protein 2 0.296
Pk61C Protein kinase 61C 0.291
Rala Ras-related protein 0.282
synj synaptojanin 0.274
cno canoe 0.261
baz bazooka 0.246
stg string 0.241
smo smoothened 0.231
ben bendless 0.227
yata CG1973 gene product from transcript CG1973-RA 0.221
CG12424 CG12424 gene product from transcript CG12424-RC 0.220
l(2)k16918 lethal (2) k16918 0.214
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.212
Ras85D Ras oncogene at 85D 0.204
Pten CG5671 gene product from transcript CG5671-RB 0.202
Arf79F ADP ribosylation factor 79F 0.202
MTF-1 Metal response element-binding Transcription Factor-1 0.199
dm diminutive 0.191
Abi Abelson interacting protein 0.191
NaCP60E Na channel protein 60E 0.189
Wnk CG7177 gene product from transcript CG7177-RA 0.179
Snap25 Synapse protein 25 0.176
Tl Toll 0.174
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.170
crb crumbs 0.170
TSG101 tumor suppressor protein 101 0.169
ken ken and barbie 0.168
Hph HIF prolyl hydroxylase 0.163
Moe Moesin 0.163
Vps16A Vacuolar protein sorting 16A 0.160
trp transient receptor potential 0.159
Flo-2 flotillin 2 0.159
dys dysfusion 0.155
CG3573 CG3573 gene product from transcript CG3573-RA 0.146
dock dreadlocks 0.143
ninaC neither inactivation nor afterpotential C 0.142
Pez CG9493 gene product from transcript CG9493-RA 0.140
CG8155 CG8155 gene product from transcript CG8155-RA 0.139
lgs legless 0.139
wge winged eye 0.137
fz frizzled 0.135
p38b CG7393 gene product from transcript CG7393-RA 0.133
Gie novel GTPase indispensable for equal segregation of chromosomes 0.133
CG17233 CG17233 gene product from transcript CG17233-RA 0.133
Jra Jun-related antigen 0.132
CG4567 CG4567 gene product from transcript CG4567-RA 0.130
Eip63E Ecdysone-induced protein 63E 0.126
raps rapsynoid 0.126
rdgB retinal degeneration B 0.124
neuroligin CG13772 gene product from transcript CG13772-RA 0.124
CG6509 CG6509 gene product from transcript CG6509-RB 0.123
puc puckered 0.121
galectin CG11372 gene product from transcript CG11372-RA 0.121
plexB plexin B 0.118
Nmnat Nicotinamide mononucleotide adenylyltransferase 0.114
Smg1 CG32743 gene product from transcript CG32743-RA 0.113
Khc-73 Kinesin-73 0.112
R Roughened 0.112
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.108
Ras64B Ras oncogene at 64B 0.105
gogo golden goal 0.101
CG32772 CG32772 gene product from transcript CG32772-RC 0.101
synaptogyrin CG10808 gene product from transcript CG10808-RA 0.100
hpo hippo 0.099
stai stathmin 0.099
Hr96 Hormone receptor-like in 96 0.099
mbt mushroom bodies tiny 0.094
bbg big bang 0.094
Smox Smad on X 0.093
Hnf4 Hepatocyte nuclear factor 4 0.093
sl small wing 0.092
Syx7 Syntaxin 7 0.091
Gbeta13F G protein beta-subunit 13F 0.090
Eph Eph receptor tyrosine kinase 0.090
ttk tramtrack 0.089
Rab6 Rab-protein 6 0.089
Cng Cyclic-nucleotide-gated ion channel protein 0.087
Fak56D Focal Adhesion Kinase 0.087
p120ctn Adherens junction protein p120 0.087
Fas3 Fasciclin 3 0.083
Myo31DF Myosin 31DF 0.083
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Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.000
OCRL oculocerebrorenal syndrome of Lowe 1.000
RAB5A RAB5A, member RAS oncogene family 0.999
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.999
GRB2 growth factor receptor-bound protein 2 0.999
EGFR epidermal growth factor receptor 0.999
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.996
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.996
SFN stratifin 0.996
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.994
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.989
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.987
RHOA ras homolog gene family, member A 0.987
DNM2 dynamin 2 0.983
RAB1A RAB1A, member RAS oncogene family 0.983
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.973
GRB7 growth factor receptor-bound protein 7 0.972
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.967
SH3KBP1 SH3-domain kinase binding protein 1 0.965
S100A11 S100 calcium binding protein A11 0.964
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.961
DOCK1 dedicator of cytokinesis 1 0.957
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.943
S100A4 S100 calcium binding protein A4 0.941
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.941
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.941
EEA1 early endosome antigen 1 0.936
NCK2 NCK adaptor protein 2 0.931
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.930
RICTOR RPTOR independent companion of MTOR, complex 2 0.919
RIN3 Ras and Rab interactor 3 0.915
S100A8 S100 calcium binding protein A8 0.914
S100A6 S100 calcium binding protein A6 0.913
ABI1 abl-interactor 1 0.913
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.912
S100B S100 calcium binding protein B 0.909
BCAR1 breast cancer anti-estrogen resistance 1 0.897
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.889
DNM1 dynamin 1 0.888
ARRB1 arrestin, beta 1 0.887
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.885
NCKAP1 NCK-associated protein 1 0.883
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.882
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.881
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.876
MARK3 MAP/microtubule affinity-regulating kinase 3 0.869
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.867
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.860
PDCD6IP programmed cell death 6 interacting protein 0.856
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.852
EXOSC3 exosome component 3 0.851
LMAN1 lectin, mannose-binding, 1 0.850
ITSN1 intersectin 1 (SH3 domain protein) 0.837
VAV1 vav 1 guanine nucleotide exchange factor 0.829
SH3RF1 SH3 domain containing ring finger 1 0.828
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.826
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.822
EEF1G eukaryotic translation elongation factor 1 gamma 0.818
BBS10 Bardet-Biedl syndrome 10 0.815
TJP2 tight junction protein 2 (zona occludens 2) 0.813
BAIAP2 BAI1-associated protein 2 0.806
RGS2 regulator of G-protein signaling 2, 24kDa 0.802
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.794
TRAF1 TNF receptor-associated factor 1 0.784
RAP1B RAP1B, member of RAS oncogene family 0.783
PLCG1 phospholipase C, gamma 1 0.779
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.770
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.770
RHOC ras homolog gene family, member C 0.769
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.768
TSC1 tuberous sclerosis 1 0.768
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.767
NCK1 NCK adaptor protein 1 0.758
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.756
NCF2 neutrophil cytosolic factor 2 0.743
TBCD tubulin folding cofactor D 0.741
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.732
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.726
CCR5 chemokine (C-C motif) receptor 5 0.715
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.706
MAPK14 mitogen-activated protein kinase 14 0.703
SH3BP2 SH3-domain binding protein 2 0.701
RRAGA Ras-related GTP binding A 0.701
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.690
GIMAP7 GTPase, IMAP family member 7 0.680
SEPT2 septin 2 0.679
S100A1 S100 calcium binding protein A1 0.679
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.666
SEC24A SEC24 family, member A (S. cerevisiae) 0.662
GOLT1B golgi transport 1B 0.657
EXOSC10 exosome component 10 0.656
RHEB Ras homolog enriched in brain 0.645
RIN1 Ras and Rab interactor 1 0.644
TSC2 tuberous sclerosis 2 0.642
TRIP6 thyroid hormone receptor interactor 6 0.636
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Epha4 Eph receptor A4 0.992
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.991
Efnb2 ephrin B2 0.977
Ephb2 Eph receptor B2 0.973
Igtp interferon gamma induced GTPase 0.963
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.956
Bcl2 B-cell leukemia/lymphoma 2 0.945
Grb2 growth factor receptor bound protein 2 0.922
Dlg4 discs, large homolog 4 (Drosophila) 0.909
Pxn paxillin 0.902
Rasgrp1 RAS guanyl releasing protein 1 0.874
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.859
Ilk integrin linked kinase 0.846
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.845
Rac1 RAS-related C3 botulinum substrate 1 0.842
Wnt5a wingless-related MMTV integration site 5A 0.826
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.820
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.806
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.804
Prkcc protein kinase C, gamma 0.800
Arrb2 arrestin, beta 2 0.799
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.790
Src Rous sarcoma oncogene 0.782
Ntf3 neurotrophin 3 0.781
Plcg1 phospholipase C, gamma 1 0.772
Mapkap1 mitogen-activated protein kinase associated protein 1 0.766
Sox10 SRY-box containing gene 10 0.765
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.759
Plxna3 plexin A3 0.759
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.723
Parva parvin, alpha 0.719
Spry4 sprouty homolog 4 (Drosophila) 0.717
Braf Braf transforming gene 0.712
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.712
Eea1 early endosome antigen 1 0.689
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.676
Lrrk2 leucine-rich repeat kinase 2 0.670
Shc3 src homology 2 domain-containing transforming protein C3 0.665
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.658
Plxna1 plexin A1 0.657
Dock1 dedicator of cytokinesis 1 0.655
Cttn cortactin 0.641
Plcb1 phospholipase C, beta 1 0.618
Add1 adducin 1 (alpha) 0.615
Akt1 thymoma viral proto-oncogene 1 0.614
Ly6h lymphocyte antigen 6 complex, locus H 0.609
Nf1 neurofibromatosis 1 0.606
Rhob ras homolog gene family, member B 0.599
Eps15 epidermal growth factor receptor pathway substrate 15 0.595
Adrb1 adrenergic receptor, beta 1 0.580
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.577
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.568
Gnao1 guanine nucleotide binding protein, alpha O 0.568
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.562
Syn2 synapsin II 0.560
Tgtp2 T-cell specific GTPase 2 0.558
Cbl Casitas B-lineage lymphoma 0.557
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.556
Mtap2 microtubule-associated protein 2 0.556
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.554
Klf7 Kruppel-like factor 7 (ubiquitous) 0.551
Cab39 calcium binding protein 39 0.546
Bax BCL2-associated X protein 0.543
Dnm1 dynamin 1 0.539
Ids iduronate 2-sulfatase 0.533
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.514
Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 0.512
Gbp2 guanylate binding protein 2 0.511
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.510
L1cam L1 cell adhesion molecule 0.510
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.507
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.504
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.500
Rhbdf1 rhomboid family 1 (Drosophila) 0.496
Plxnb1 plexin B1 0.495
Nrbp2 nuclear receptor binding protein 2 0.495
Efnb1 ephrin B1 0.494
Dusp1 dual specificity phosphatase 1 0.494
Mark4 MAP/microtubule affinity-regulating kinase 4 0.492
Selplg selectin, platelet (p-selectin) ligand 0.481
Pou3f2 POU domain, class 3, transcription factor 2 0.481
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.475
Grid1 glutamate receptor, ionotropic, delta 1 0.466
Vapa vesicle-associated membrane protein, associated protein A 0.459
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.457
Gpr27 G protein-coupled receptor 27 0.455
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.454
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.451
Cd40 CD40 antigen 0.449
Ctnnd1 catenin (cadherin associated protein), delta 1 0.446
Tspan9 tetraspanin 9 0.444
Ptp4a2 protein tyrosine phosphatase 4a2 0.443
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.440
Rhoc ras homolog gene family, member C 0.429
Rtkn rhotekin 0.429
Tmem30a transmembrane protein 30A 0.428
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.428
Mllt1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.422
Hoxd11 homeobox D11 0.421
Pnp2 purine-nucleoside phosphorylase 2 0.418
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Arl1 ADP-ribosylation factor-like 1 0.414
Hk1 hexokinase 1 0.255
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.235
Rab1b RAB1B, member RAS oncogene family 0.206
Pja2 praja 2, RING-H2 motif containing 0.192
Rab1 RAB1, member RAS oncogene family 0.161
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.151
Rab5a RAB5A, member RAS oncogene family 0.151
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.150
Gria2 glutamate receptor, ionotropic, AMPA 2 0.138
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.138
Sdc3 syndecan 3 0.125
Arpc2 actin related protein 2/3 complex, subunit 2 0.112
Epas1 endothelial PAS domain protein 1 0.110
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.110
Jtb jumping translocation breakpoint 0.110
Amph amphiphysin 0.108
Copb1 coatomer protein complex, subunit beta 1 0.107
Csnk1g2 casein kinase 1, gamma 2 0.105
Adrbk1 adrenergic, beta, receptor kinase 1 0.104
Pum1 pumilio homolog 1 (Drosophila) 0.102
Usf2 upstream transcription factor 2, c-fos interacting 0.098
Stxbp1 syntaxin binding protein 1 0.098
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.096
Svop SV2 related protein 0.081
Limd2 LIM domain containing 2 0.078
Tek TEK tyrosine kinase, endothelial 0.078
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.077
Csk c-src tyrosine kinase 0.076
Adora2a adenosine A2a receptor 0.076
Rab18 RAB18, member RAS oncogene family 0.075
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.074
Mllt1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.073
Prkch protein kinase C, eta 0.070
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.069
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.068
Pctk1 PCTAIRE protein kinase 1 0.068
Wdr7 WD repeat domain 7 0.068
Cdk7 cyclin-dependent kinase 7 0.068
RT1-DMa RT1 class II, locus DMa 0.068
Zfp260 zinc finger protein 260 0.067
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.067
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.067
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.064
Snap25 synaptosomal-associated protein 25 0.062
Arf4 ADP-ribosylation factor 4 0.062
Pdcl phosducin-like 0.061
Sstr1 somatostatin receptor 1 0.060
Dlg3 discs, large homolog 3 (Drosophila) 0.060
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.059
Nptn neuroplastin 0.059
Exoc5 exocyst complex component 5 0.057
Pcnxl3 pecanex-like 3 (Drosophila) 0.057
Scarb1 scavenger receptor class B, member 1 0.056
A4galt alpha 1,4-galactosyltransferase 0.056
Camk4 calcium/calmodulin-dependent protein kinase IV 0.055
Rhoa ras homolog gene family, member A 0.054
Clcn7 chloride channel 7 0.054
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.054
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.053
Sh3gl2 SH3-domain GRB2-like 2 0.052
Itpka inositol 1,4,5-trisphosphate 3-kinase A 0.051
Lpcat4 lysophosphatidylcholine acyltransferase 4 0.051
Stx2 syntaxin 2 0.051
Homer1 homer homolog 1 (Drosophila) 0.051
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.050
Bin1 bridging integrator 1 0.049
Gipc1 GIPC PDZ domain containing family, member 1 0.049
Dock9 dedicator of cytokinesis 9 0.049
Cfp complement factor properdin 0.049
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.048
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.048
Akap1 A kinase (PRKA) anchor protein 1 0.048
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.048
Prrx1 paired related homeobox 1 0.048
Cyth1 cytohesin 1 0.048
Cops7a COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) 0.048
Eif3d eukaryotic translation initiation factor 3, subunit D 0.047
Sox17 SRY (sex determining region Y)-box 17 0.047
Rap1b RAP1B, member of RAS oncogene family 0.046
Robo2 roundabout homolog 2 (Drosophila) 0.046
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.045
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.045
Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.045
Fgfr2 fibroblast growth factor receptor 2 0.045
Vps52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.044
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.044
Mapk7 mitogen-activated protein kinase 7 0.044
Slit3 slit homolog 3 (Drosophila) 0.044
Hr hairless 0.043
Eif4e2 eukaryotic translation initiation factor 4E family member 2 0.043
Clec4a1 C-type lectin domain family 4, member a1 0.042
Tgfbr2 transforming growth factor, beta receptor II 0.042
Capn2 calpain 2 0.041
Nckap1 NCK-associated protein 1 0.041
Dnm2 dynamin 2 0.041
Rab6a RAB6A, member RAS oncogene family 0.041
RGD1309036 hypothetical LOC292874 0.041
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.041
Synj1 synaptojanin 1 0.041
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STE11 Ste11p 0.946
GDI1 Gdi1p 0.878
GYL1 Gyl1p 0.718
ROM2 Rom2p 0.590
GCD6 Gcd6p 0.566
YIP3 Yip3p 0.543
YPT52 Ypt52p 0.538
STE5 Ste5p 0.509
YPT1 Ypt1p 0.408
RHO1 Rho1p 0.386
AVO1 Avo1p 0.330
YPT31 Ypt31p 0.324
VPS15 Vps15p 0.323
MKK1 Mkk1p 0.300
TRS65 Trs65p 0.297
STE4 Ste4p 0.292
SEC4 Sec4p 0.274
SEC2 Sec2p 0.233
YPT10 Ypt10p 0.231
PEP5 Pep5p 0.227
TOM1 Tom1p 0.215
BET3 Bet3p 0.194
VPS41 Vps41p 0.186
YPT7 Ypt7p 0.184
RFC1 Rfc1p 0.168
ACK1 Ack1p 0.161
FMS1 Fms1p 0.157
KOG1 Kog1p 0.156
IRA1 Ira1p 0.136
VPS21 Vps21p 0.135
BFR1 Bfr1p 0.132
MRS6 Mrs6p 0.129
SEC16 Sec16p 0.123
GPB2 Gpb2p 0.120
GIC2 Gic2p 0.119
SLM2 Slm2p 0.119
MDS3 Mds3p 0.111
SEC21 Sec21p 0.104
SSK2 Ssk2p 0.101
DCN1 Dcn1p 0.100
STE2 Ste2p 0.100
YIP1 Yip1p 0.098
TPK3 Tpk3p 0.094
PKC1 Pkc1p 0.093
RGD1 Rgd1p 0.091
ELP4 Elp4p 0.090
SED5 Sed5p 0.090
YIP4 Yip4p 0.088
SEC13 Sec13p 0.087
BUD6 Bud6p 0.087
STT4 Stt4p 0.086
YPT53 Ypt53p 0.086
TOR2 Tor2p 0.084
YPT6 Ypt6p 0.083
CHS1 Chs1p 0.083
MNN9 Mnn9p 0.082
PPX1 Ppx1p 0.078
NIP7 Nip7p 0.076
TRX1 Trx1p 0.076
IOC3 Ioc3p 0.074
RAS1 Ras1p 0.074
BUD8 Bud8p 0.073
MYO1 Myo1p 0.073
DNF3 Dnf3p 0.072
SMM1 Smm1p 0.072
SFB2 Sfb2p 0.072
GLO3 Glo3p 0.071
TOR1 Tor1p 0.071
YPP1 Ypp1p 0.070
YDR186C hypothetical protein 0.069
FIR1 Fir1p 0.069
HYP2 Hyp2p 0.069
NYV1 Nyv1p 0.068
MCM6 Mcm6p 0.068
YFR016C hypothetical protein 0.067
TUS1 Tus1p 0.067
RPM2 Rpm2p 0.066
CCT4 Cct4p 0.066
SPA2 Spa2p 0.066
NOP13 Nop13p 0.064
PRS2 Prs2p 0.063
URA6 Ura6p 0.061
MST1 Mst1p 0.061
RAS2 Ras2p 0.060
BRN1 Brn1p 0.058
MON1 Mon1p 0.058
LSB1 Lsb1p 0.058
YLR257W hypothetical protein 0.058
EBP2 Ebp2p 0.057
YHR127W hypothetical protein 0.056
INP53 Inp53p 0.055
VAM6 Vam6p 0.054
TRS31 Trs31p 0.053
MDH1 Mdh1p 0.053
ERB1 Erb1p 0.051
NAT1 Nat1p 0.051
SAR1 Sar1p 0.051
SEC3 Sec3p 0.050
YCR007C hypothetical protein 0.050
RHO5 Rho5p 0.050