The network for 'neuron projection development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

Danio rerio
Name Description Probability Func Analog Organism
pitx3 paired-like homeodomain transcription factor 3 0.998
notch1a notch homolog 1a 0.997
gli1 GLI-Kruppel family member 1 0.993
fezf2 FEZ family zinc finger 2 0.992
ndr2 nodal-related 2 0.992
gdf6a growth differentiation factor 6a 0.991
lhx2b LIM homeobox 2b 0.989
ttna titin a 0.972
ptch2 patched 2 0.968
chd chordin 0.965
nes nestin 0.961
olig2 oligodendrocyte lineage transcription factor 2 0.953
dla deltaA 0.953
dlb deltaB 0.952
epha4b eph receptor A4b 0.950
six3b sine oculis homeobox homolog 3b 0.947
fn1 fibronectin 1 0.942
sox2 SRY-box containing gene 2 0.936
rx3 retinal homeobox gene 3 0.926
nrp1a neuropilin 1a 0.924
ncam1a neural cell adhesion molecule 1a 0.914
dag1 dystroglycan 1 0.908
fgf3 fibroblast growth factor 3 0.906
nxph1 neurexophilin 1 0.903
robo2 roundabout homolog 2 0.896
foxn4 forkhead box N4 0.896
pax6b paired box gene 6b 0.894
ephb4b eph receptor B4b 0.893
lamc1 laminin, gamma 1 0.886
gli2a GLI-Kruppel family member GLI2a 0.886
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.885
flh floating head 0.881
atoh7 atonal homolog 7 0.876
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.872
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.870
notch2 notch homolog 2 0.864
cntn2 contactin 2 0.864
wnt10a wingless-type MMTV integration site family, member 10a 0.862
wnt11r wingless-type MMTV integration site family, member 11, related 0.857
shha sonic hedgehog a 0.833
alcamb activated leukocyte cell adhesion molecule b 0.830
itgav integrin, alpha V 0.824
fstl1b follistatin-like 1b 0.820
otx1a orthodenticle homolog 1a 0.805
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.803
six3a sine oculis homeobox homolog 3a 0.801
smo smoothened homolog (Drosophila) 0.798
neurod neurogenic differentiation 0.794
prdm14 PR domain containing 14 0.786
fgfr1a fibroblast growth factor receptor 1a 0.780
otpb orthopedia homolog b 0.777
lamb1a laminin, beta 1a 0.776
tbx1 T-box 1 0.775
gata2a GATA-binding protein 2a 0.770
foxp2 forkhead box P2 0.766
lhx5 LIM homeobox 5 0.760
ephb4a eph receptor B4a 0.759
dlx5a distal-less homeobox gene 5a 0.757
syn2b synapsin IIb 0.756
crabp2a cellular retinoic acid binding protein 2, a 0.753
pdlim4 PDZ and LIM domain 4 0.752
pcdh18b protocadherin 18b 0.747
pax8 paired box gene 8 0.746
arx aristaless related homeobox 0.745
her9 hairy-related 9 0.738
gro1 groucho 1 0.738
foxd3 forkhead box D3 0.736
dpysl2b dihydropyrimidinase-like 2b 0.730
mfn2 mitofusin 2 0.729
wnt3 wingless-type MMTV integration site family, member 3 0.728
coe2 coe2 0.726
fgf10a fibroblast growth factor 10a 0.726
her4.2 hairy-related 4.2 0.726
cdh23 cadherin-like 23 0.719
fras1 Fraser syndrome 1 0.710
igf1rb insulin-like growth factor 1b receptor 0.708
ascl1a achaete-scute complex-like 1a (Drosophila) 0.704
wnt11 wingless-type MMTV integration site family, member 11 0.702
olfm2 olfactomedin 2 0.696
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.694
kal1a Kallmann syndrome 1a sequence 0.691
col2a1a collagen type II, alpha-1a 0.684
phox2a paired-like homeobox 2a 0.683
bmp2a bone morphogenetic protein 2a 0.681
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.677
spry4 sprouty (Drosophila) homolog 4 0.667
otpa orthopedia homolog a 0.664
sdcbp syndecan binding protein (syntenin) 0.658
egr2b early growth response 2b 0.657
slit3 slit (Drosophila) homolog 3 0.656
eya1 eyes absent homolog 1 0.654
otx5 orthodenticle homolog 5 0.646
irx4b iroquois homeobox protein 4b 0.646
pou3f1 POU class 3 homeobox 1 0.644
supt6h suppressor of Ty 6 homolog 0.643
mbp myelin basic protein 0.639
ntla no tail a 0.632
stmn2b stathmin-like 2b 0.630
gpr98 G protein-coupled receptor 98 0.627
pcdh10a protocadherin 10a 0.625
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.974
pha-4 Protein PHA-4 0.970
ceh-20 Protein CEH-20 0.887
ten-1 Protein TEN-1 0.858
hlh-1 Protein HLH-1 0.835
hlh-2 Protein HLH-2 0.823
pry-1 Protein PRY-1 0.810
daf-11 Protein DAF-11 0.798
hbl-1 Protein HBL-1 0.773
ldb-1 Protein LDB-1 0.744
sli-1 Protein SLI-1 0.715
unc-73 Protein UNC-73 0.708
bar-1 Protein BAR-1 0.686
ain-1 Protein AIN-1 0.685
egl-13 Protein EGL-13 0.680
egl-46 Protein EGL-46 0.666
cye-1 Protein CYE-1 0.648
elt-6 Protein ELT-6 0.636
ajm-1 Protein AJM-1 0.623
mab-5 Protein MAB-5 0.612
unc-52 Protein UNC-52 0.601
T28F4.1 Protein T28F4.1 0.597
sma-1 Protein SMA-1 0.564
nhr-67 Protein NHR-67 0.563
zip-7 Protein ZIP-7 0.556
eor-1 Protein EOR-1 0.544
peb-1 Protein PEB-1 0.538
unc-42 Protein UNC-42 0.520
T27A3.1 Protein T27A3.1 0.518
sma-6 Protein SMA-6 0.515
unc-62 Protein UNC-62 0.513
unc-70 Protein UNC-70 0.492
lin-29 Protein LIN-29 0.490
egl-8 Protein EGL-8 0.481
chd-7 Protein CHD-7 0.467
asd-1 Protein ASD-1 0.455
vab-10 Protein VAB-10 0.446
unc-6 Protein UNC-6 0.435
eif-3.I Protein EIF-3.I 0.433
lsy-2 Protein LSY-2 0.432
tbc-2 Protein TBC-2 0.431
fkh-2 Protein FKH-2 0.424
skp-1 Protein SKP-1 0.420
cam-1 Protein CAM-1 0.418
C11E4.6 Protein C11E4.6 0.414
egl-5 Protein EGL-5 0.413
sem-5 Protein SEM-5 0.409
pop-1 Protein POP-1 0.401
flt-1 Protein FLT-1 0.398
spdl-1 Protein SPDL-1 0.396
nhr-45 Protein NHR-45 0.395
acs-4 Protein ACS-4 0.373
trim-9 Protein TRIM-9 0.368
unc-53 Protein UNC-53 0.363
sax-3 Protein SAX-3 0.354
teg-4 Protein TEG-4 0.354
let-60 Protein LET-60 0.351
unc-40 Protein UNC-40 0.350
C54E4.2 Protein C54E4.2 0.349
ceh-34 Protein CEH-34 0.346
pbrm-1 Protein PBRM-1 0.345
cdh-3 Protein CDH-3 0.339
vab-3 Protein VAB-3 0.330
let-2 Protein LET-2 0.330
unc-115 Protein UNC-115 0.327
hid-1 Protein HID-1 0.326
soc-2 Protein SOC-2 0.326
mig-2 Protein MIG-2 0.325
F53F10.2 Protein F53F10.2 0.320
R90.1 Protein R90.1 0.317
cyk-4 Protein CYK-4 0.314
CELE_Y41E3.11 Protein Y41E3.11 0.313
gsp-1 Protein GSP-1 0.313
epi-1 Protein EPI-1 0.307
lin-48 Protein LIN-48 0.307
unc-43 Protein UNC-43 0.307
cash-1 Protein CASH-1 0.306
irx-1 Protein IRX-1 0.301
tlk-1 Protein TLK-1 0.300
K10D6.4 Protein K10D6.4 0.297
gon-4 Protein GON-4 0.295
spc-1 Protein SPC-1 0.294
sax-7 Protein SAX-7 0.293
syg-1 Protein SYG-1 0.293
eps-8 Protein EPS-8 0.292
egl-15 Protein EGL-15 0.289
madf-5 Protein MADF-5 0.284
srgp-1 Protein SRGP-1 0.282
R10E12.2 Protein R10E12.2 0.282
F10G8.9 Protein F10G8.9 0.276
pxf-1 Protein PXF-1 0.275
pal-1 Protein PAL-1 0.272
aap-1 Protein AAP-1 0.268
egl-44 Protein EGL-44 0.264
unc-104 Protein UNC-104 0.263
cin-4 Protein CIN-4 0.258
ttyh-1 Protein TTYH-1 0.256
mec-4 Protein MEC-4 0.254
tax-4 Protein TAX-4 0.251
ceh-48 Protein CEH-48 0.250
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FYN FYN oncogene related to SRC, FGR, YES 1.000
EGFR epidermal growth factor receptor 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
QKI quaking homolog, KH domain RNA binding (mouse) 0.998
ATXN1 ataxin 1 0.996
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.993
GRB2 growth factor receptor-bound protein 2 0.993
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.989
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.987
SMAD2 SMAD family member 2 0.984
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.984
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.983
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.974
FN1 fibronectin 1 0.970
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.969
FLNA filamin A, alpha 0.964
HDAC2 histone deacetylase 2 0.958
ATN1 atrophin 1 0.957
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.956
BCAR1 breast cancer anti-estrogen resistance 1 0.950
RBBP4 retinoblastoma binding protein 4 0.927
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.923
JUN jun proto-oncogene 0.922
SYK spleen tyrosine kinase 0.908
HDAC1 histone deacetylase 1 0.898
FGFR1 fibroblast growth factor receptor 1 0.892
APP amyloid beta (A4) precursor protein 0.888
LCK lymphocyte-specific protein tyrosine kinase 0.885
ITSN1 intersectin 1 (SH3 domain protein) 0.874
CREBBP CREB binding protein 0.864
NCOR1 nuclear receptor corepressor 1 0.864
MET met proto-oncogene (hepatocyte growth factor receptor) 0.854
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.817
VAV1 vav 1 guanine nucleotide exchange factor 0.815
ZMYND11 zinc finger, MYND-type containing 11 0.804
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.800
WASL Wiskott-Aldrich syndrome-like 0.799
MAPK8 mitogen-activated protein kinase 8 0.798
DLG4 discs, large homolog 4 (Drosophila) 0.772
FOS FBJ murine osteosarcoma viral oncogene homolog 0.755
NCAM1 neural cell adhesion molecule 1 0.745
CREB1 cAMP responsive element binding protein 1 0.742
PTK2 PTK2 protein tyrosine kinase 2 0.739
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.733
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.722
EP300 E1A binding protein p300 0.719
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.718
SMAD3 SMAD family member 3 0.707
MAPT microtubule-associated protein tau 0.702
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.695
RB1 retinoblastoma 1 0.684
ATF2 activating transcription factor 2 0.680
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.671
PLCG1 phospholipase C, gamma 1 0.668
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.658
AR androgen receptor 0.657
LAT linker for activation of T cells 0.651
IQGAP1 IQ motif containing GTPase activating protein 1 0.648
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.644
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.636
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.632
BAIAP2 BAI1-associated protein 2 0.628
TAL1 T-cell acute lymphocytic leukemia 1 0.622
ARHGAP1 Rho GTPase activating protein 1 0.618
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.614
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.610
JAG1 jagged 1 0.609
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.606
PTPRC protein tyrosine phosphatase, receptor type, C 0.589
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.585
RUNX1 runt-related transcription factor 1 0.573
ABI1 abl-interactor 1 0.568
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.566
YAP1 Yes-associated protein 1 0.562
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.558
SOS1 son of sevenless homolog 1 (Drosophila) 0.555
MPRIP myosin phosphatase Rho interacting protein 0.554
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.546
RERE arginine-glutamic acid dipeptide (RE) repeats 0.542
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.526
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.525
SMAD4 SMAD family member 4 0.523
STRN3 striatin, calmodulin binding protein 3 0.517
JAK2 Janus kinase 2 0.515
NTNG1 netrin G1 0.512
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.512
NCK1 NCK adaptor protein 1 0.511
PRKCZ protein kinase C, zeta 0.506
RAB1A RAB1A, member RAS oncogene family 0.504
STK3 serine/threonine kinase 3 0.504
MAP2K4 mitogen-activated protein kinase kinase 4 0.502
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.493
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.491
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.490
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.489
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.483
CTNND1 catenin (cadherin-associated protein), delta 1 0.481
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.479
ARRB1 arrestin, beta 1 0.477
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.847
Dlg4 discs, large homolog 4 (Drosophila) 0.803
Robo1 roundabout homolog 1 (Drosophila) 0.681
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.666
Lin7b lin-7 homolog b (C. elegans) 0.659
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.638
Nrxn1 neurexin 1 0.571
Sp4 Sp4 transcription factor 0.570
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.557
Itgb1 integrin, beta 1 0.525
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.525
Jak1 Janus kinase 1 0.509
Rap1b RAP1B, member of RAS oncogene family 0.504
Nrxn3 neurexin 3 0.501
Rhoa ras homolog gene family, member A 0.457
Nfib nuclear factor I/B 0.452
Grip1 glutamate receptor interacting protein 1 0.449
Sncb synuclein, beta 0.440
Gria2 glutamate receptor, ionotropic, AMPA 2 0.435
Dchs1 dachsous 1 (Drosophila) 0.430
Dlg3 discs, large homolog 3 (Drosophila) 0.425
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.422
Pfn1 profilin 1 0.410
Klk1c10l2 kallikrein 1-related peptidase c10-like 2 0.399
Trib1 tribbles homolog 1 (Drosophila) 0.391
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.389
Ednrb endothelin receptor type B 0.383
Rimbp2 RIMS binding protein 2 0.381
Jak2 Janus kinase 2 0.376
Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.373
Sv2a synaptic vesicle glycoprotein 2a 0.368
Smad4 SMAD family member 4 0.365
Hspb1 heat shock protein 1 0.364
Atf3 activating transcription factor 3 0.359
Utrn utrophin 0.348
Grm5 glutamate receptor, metabotropic 5 0.343
Tpm3 tropomyosin 3, gamma 0.343
Anxa2 annexin A2 0.341
Nfia nuclear factor I/A 0.339
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.339
Errfi1 ERBB receptor feedback inhibitor 1 0.336
Fyn FYN oncogene related to SRC, FGR, YES 0.333
Vcan versican 0.332
Calcrl calcitonin receptor-like 0.326
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.325
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.322
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.320
Akap5 A kinase (PRKA) anchor protein 5 0.317
Prrx1 paired related homeobox 1 0.317
Cyth3 cytohesin 3 0.315
App amyloid beta (A4) precursor protein 0.312
Cadm1 cell adhesion molecule 1 0.310
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.309
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.300
Kcnd2 potassium voltage-gated channel, Shal-related subfamily, member 2 0.295
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.295
Bdkrb2 bradykinin receptor B2 0.293
Tmod2 tropomodulin 2 0.286
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.285
Cttn cortactin 0.284
Map2 microtubule-associated protein 2 0.283
Gata3 GATA binding protein 3 0.281
Nrg1 neuregulin 1 0.280
Map1b microtubule-associated protein 1B 0.279
Astn1 astrotactin 1 0.278
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.276
Pcdhgc3 protocadherin gamma subfamily C, 3 0.275
Strn striatin, calmodulin binding protein 0.275
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.273
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.271
Aqp4 aquaporin 4 0.271
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.268
Pls3 plastin 3 (T-isoform) 0.268
Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 0.267
Pde4b phosphodiesterase 4B, cAMP specific 0.267
Nrcam neuronal cell adhesion molecule 0.266
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.266
Galr3 galanin receptor 3 0.265
Mmp10 matrix metallopeptidase 10 0.264
Vav1 vav 1 guanine nucleotide exchange factor 0.264
Snap25 synaptosomal-associated protein 25 0.262
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.261
Mapt microtubule-associated protein tau 0.258
Rab6b RAB6B, member RAS oncogene family 0.257
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.256
Slc4a3 solute carrier family 4 (anion exchanger), member 3 0.254
Prkcd protein kinase C, delta 0.254
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.253
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.253
Bmp3 bone morphogenetic protein 3 0.252
Lzts1 leucine zipper, putative tumor suppressor 1 0.252
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.252
Pou2f2 POU class 2 homeobox 2 0.252
Cplx1 complexin 1 0.250
Tgfbr2 transforming growth factor, beta receptor II 0.249
Scn3a sodium channel, voltage-gated, type III, alpha 0.248
Cd4 Cd4 molecule 0.246
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.245
Plp1 proteolipid protein 1 0.241
Emp1 epithelial membrane protein 1 0.240
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism