The network for 'cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell migration

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

Danio rerio
Name Description Probability Func Analog Organism
shha sonic hedgehog a 0.998
tbx1 T-box 1 0.989
fn1 fibronectin 1 0.989
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.987
fgf3 fibroblast growth factor 3 0.987
sulf1 sulfatase 1 0.974
gli2a GLI-Kruppel family member GLI2a 0.971
spry4 sprouty (Drosophila) homolog 4 0.971
fgf8a fibroblast growth factor 8 a 0.971
efnb2a ephrin B2a 0.968
sox19a SRY-box containing gene 19a 0.959
lamc1 laminin, gamma 1 0.954
lamb1a laminin, beta 1a 0.951
gata3 GATA-binding protein 3 0.950
boc brother of CDO 0.947
tll1 tolloid-like 1 0.944
kdrl kinase insert domain receptor like 0.939
bmp4 bone morphogenetic protein 4 0.933
cdh23 cadherin-like 23 0.929
spns2 spinster homolog 2 (Drosophila) 0.928
dag1 dystroglycan 1 0.917
bmp7a bone morphogenetic protein 7a 0.915
pitx3 paired-like homeodomain transcription factor 3 0.907
hoxd4a homeo box D4a 0.885
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.881
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.855
nkx2.1a NK2 homeobox 1a 0.850
hsp90a.1 heat shock protein 90-alpha 1 0.848
ilk integrin linked kinase 0.845
alcamb activated leukocyte cell adhesion molecule b 0.842
emx3 empty spiracles homeobox 3 0.841
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.836
hoxc8a homeo box C8a 0.835
fstl1b follistatin-like 1b 0.835
tbx2b T-box 2b 0.835
gdf6a growth differentiation factor 6a 0.829
fgfr2 fibroblast growth factor receptor 2 0.825
rx3 retinal homeobox gene 3 0.824
lama2 laminin, alpha 2 0.814
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.812
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.811
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.811
fbn2b fibrillin 2b 0.810
hoxa4a homeo box A4a 0.797
tpm4 tropomyosin 4 0.796
lama4 laminin, alpha 4 0.791
foxi1 forkhead box I1 0.779
traf4a tnf receptor-associated factor 4a 0.778
wnt11r wingless-type MMTV integration site family, member 11, related 0.778
robo2 roundabout homolog 2 0.777
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.775
lft2 lefty2 0.773
foxa2 forkhead box A2 0.771
wnt8b wingless-type MMTV integration site family, member 8b 0.767
prdm1a PR domain containing 1a, with ZNF domain 0.766
yap1 Yes-associated protein 1 0.763
fzd5 frizzled homolog 5 0.759
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.759
six4b sine oculis homeobox homolog 4b 0.753
chsy1 chondroitin sulfate synthase 1 0.750
znf703 zinc finger protein 703 0.748
notch1a notch homolog 1a 0.745
hoxb2a homeo box B2a 0.740
egr2b early growth response 2b 0.736
col15a1b collagen, type XV, alpha 1b 0.736
nrg2a neuregulin 2a 0.735
cxcr4a chemokine (C-X-C motif) receptor 4a 0.729
itgb1b integrin, beta 1b 0.729
nrp1a neuropilin 1a 0.726
foxh1 forkhead box H1 0.723
hnf1ba HNF1 homeobox Ba 0.717
irx3a iroquois homeobox protein 3a 0.716
myf5 myogenic factor 5 0.708
wnt4a wingless-type MMTV integration site family, member 4a 0.696
bon bonnie and clyde 0.693
mapk1 mitogen-activated protein kinase 1 0.686
zic4 zic family member 4 0.684
hoxb8a homeo box B8a 0.684
hoxb6a homeo box B6a 0.682
dld deltaD 0.672
bmper BMP binding endothelial regulator 0.672
col12a1 collagen, type XII, alpha 1 0.671
hoxc6a homeo box C6a 0.659
eomesa eomesodermin homolog a 0.659
lft1 lefty1 0.658
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.654
wif1 wnt inhibitory factor 1 0.652
epha4b eph receptor A4b 0.651
hhip hedgehog interacting protein 0.651
dmd dystrophin 0.648
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.647
tbx20 T-box 20 0.646
dlc deltaC 0.640
notch3 notch homolog 3 0.635
hoxb3a homeo box B3a 0.634
tnfsf10l tumor necrosis factor (ligand) superfamily, member 10 like 0.631
lcp1 lymphocyte cytosolic plastin 1 0.629
lamb2 laminin, beta 2 (laminin S) 0.627
her6 hairy-related 6 0.626
hoxa2b homeo box A2b 0.624
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.993
hlh-2 Protein HLH-2 0.991
mig-5 Protein MIG-5 0.971
pha-4 Protein PHA-4 0.970
epi-1 Protein EPI-1 0.955
emb-9 Protein EMB-9 0.953
bar-1 Protein BAR-1 0.928
sem-5 Protein SEM-5 0.921
unc-62 Protein UNC-62 0.918
hbl-1 Protein HBL-1 0.909
elt-6 Protein ELT-6 0.888
unc-73 Protein UNC-73 0.855
ten-1 Protein TEN-1 0.855
hlh-1 Protein HLH-1 0.842
nhr-67 Protein NHR-67 0.836
egl-13 Protein EGL-13 0.830
icd-1 Protein ICD-1 0.814
atn-1 Protein ATN-1 0.792
vab-3 Protein VAB-3 0.789
vab-1 Protein VAB-1 0.787
unc-98 Protein UNC-98 0.762
unc-42 Protein UNC-42 0.756
act-4 Protein ACT-4 0.730
let-60 Protein LET-60 0.709
egl-15 Protein EGL-15 0.703
hnd-1 Protein HND-1 0.685
tag-260 Protein TAG-260 0.679
lam-2 Protein LAM-2 0.678
sax-3 Protein SAX-3 0.675
plc-1 Protein PLC-1 0.663
mig-6 Protein MIG-6 0.660
egg-6 Protein EGG-6 0.659
C32D5.3 Protein C32D5.3 0.649
dpy-26 Protein DPY-26 0.644
T21B6.3 Protein T21B6.3 0.638
teg-4 Protein TEG-4 0.637
sop-2 Protein SOP-2 0.636
egl-27 Protein EGL-27 0.632
mbk-2 Protein MBK-2 0.632
mab-5 Protein MAB-5 0.631
ztf-4 Protein ZTF-4 0.626
lsy-2 Protein LSY-2 0.625
Y44E3A.6 Protein Y44E3A.6 0.621
C54E4.2 Protein C54E4.2 0.619
ifa-1 Protein IFA-1 0.619
hse-5 Protein HSE-5 0.615
eor-2 Protein EOR-2 0.598
lin-45 Protein LIN-45 0.588
zfp-1 Protein ZFP-1 0.583
T27A3.1 Protein T27A3.1 0.556
eftu-2 Protein EFTU-2 0.547
par-5 Protein PAR-5 0.544
dlc-1 Protein DLC-1 0.544
egl-46 Protein EGL-46 0.539
ldb-1 Protein LDB-1 0.538
wrm-1 Protein WRM-1 0.538
npp-7 Protein NPP-7 0.537
mix-1 Protein MIX-1 0.534
ntl-4 Protein NTL-4 0.526
egl-44 Protein EGL-44 0.525
irx-1 Protein IRX-1 0.525
lag-1 Protein LAG-1 0.522
emb-5 Protein EMB-5 0.517
fkh-2 Protein FKH-2 0.515
lin-23 Protein LIN-23 0.507
sli-1 Protein SLI-1 0.503
T09B4.5 Protein T09B4.5 0.503
let-2 Protein LET-2 0.502
unc-52 Protein UNC-52 0.502
hmg-1.2 Protein HMG-1.2 0.497
tbb-2 Protein TBB-2 0.492
Y48A6B.3 Protein Y48A6B.3 0.490
daf-1 Protein DAF-1 0.484
hum-5 Protein HUM-5 0.482
lin-29 Protein LIN-29 0.479
rig-5 Protein RIG-5 0.478
zyg-8 Protein ZYG-8 0.477
asd-1 Protein ASD-1 0.472
vav-1 Protein VAV-1 0.470
pat-6 Protein PAT-6 0.465
prp-21 Protein PRP-21 0.457
mom-2 Protein MOM-2 0.453
T28B4.1 Protein T28B4.1 0.448
zyg-9 Protein ZYG-9 0.447
smp-1 Protein SMP-1 0.441
unc-60 Protein UNC-60 0.441
set-16 Protein SET-16 0.439
nhr-25 Protein NHR-25 0.433
ceh-16 Protein CEH-16 0.432
apr-1 Protein APR-1 0.432
sel-7 Protein SEL-7 0.431
mbk-1 Protein MBK-1 0.431
egl-8 Protein EGL-8 0.431
gex-3 Protein GEX-3 0.428
cogc-2 Protein COGC-2 0.428
suf-1 Protein SUF-1 0.426
unc-120 Protein UNC-120 0.422
ina-1 Protein INA-1 0.418
ced-10 Protein CED-10 0.413
F59A3.4 Protein F59A3.4 0.412
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Drosophila melanogaster
Name Description Probability Func Analog Organism
mbc myoblast city 1.000
Ced-12 CG5336 gene product from transcript CG5336-RA 1.000
Rac1 CG2248 gene product from transcript CG2248-RA 1.000
dock dreadlocks 1.000
par-1 CG8201 gene product from transcript CG8201-RA 1.000
Egfr Epidermal growth factor receptor 1.000
l(2)gl lethal (2) giant larvae 0.998
ttv tout-velu 0.998
yu CG3249 gene product from transcript CG3249-RA 0.998
msn misshapen 0.998
Ras85D Ras oncogene at 85D 0.997
aop anterior open 0.997
kuz kuzbanian 0.997
Lis-1 Lissencephaly-1 0.997
Rab5 Rab-protein 5 0.997
Rho1 CG8416 gene product from transcript CG8416-RB 0.997
htl heartless 0.996
Hem HEM-protein 0.996
Vang Van Gogh 0.995
Shc SHC-adaptor protein 0.995
stai stathmin 0.994
spas spastin 0.993
Tm1 Tropomyosin 1 0.993
put punt 0.992
shi shibire 0.992
zip zipper 0.991
ik2 IkappaB kinase-like 2 0.991
baz bazooka 0.990
bs blistered 0.990
CG8155 CG8155 gene product from transcript CG8155-RA 0.989
BicD Bicaudal D 0.989
Rab11 Rab-protein 11 0.989
Stat92E Signal-transducer and activator of transcription protein at 92E 0.988
egh egghead 0.985
chic chickadee 0.982
dia diaphanous 0.981
esg escargot 0.980
mys myospheroid 0.978
Pvr PDGF- and VEGF-receptor related 0.977
sqh spaghetti squash 0.973
dm diminutive 0.971
spi spitz 0.970
dome domeless 0.967
drk downstream of receptor kinase 0.965
srp serpent 0.965
ex expanded 0.962
pbl pebble 0.960
CycA Cyclin A 0.959
Cortactin CG3637 gene product from transcript CG3637-RA 0.955
Smox Smad on X 0.953
eya eyes absent 0.953
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.952
CG12424 CG12424 gene product from transcript CG12424-RC 0.945
abd-A abdominal A 0.943
tsr twinstar 0.943
shg shotgun 0.939
rhea CG6831 gene product from transcript CG6831-RA 0.939
Mhc Myosin heavy chain 0.933
stan starry night 0.933
insc inscuteable 0.931
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.927
alpha-Cat alpha Catenin 0.923
fra frazzled 0.922
JIL-1 CG6297 gene product from transcript CG6297-RA 0.921
EcR Ecdysone receptor 0.919
arm armadillo 0.917
CaMKII Calcium/calmodulin-dependent protein kinase II 0.917
slmb supernumerary limbs 0.917
loco locomotion defects 0.916
tkv thickveins 0.913
CalpB Calpain-B 0.913
Fmr1 CG6203 gene product from transcript CG6203-RC 0.912
Apc APC-like 0.911
dsh dishevelled 0.905
WASp CG1520 gene product from transcript CG1520-RA 0.905
ena enabled 0.904
pan pangolin 0.900
lkb1 CG9374 gene product from transcript CG9374-RJ 0.898
gbb glass bottom boat 0.894
Rala Ras-related protein 0.888
tgo tango 0.887
egl egalitarian 0.886
hep hemipterous 0.886
fz frizzled 0.884
Fas2 Fasciclin 2 0.878
cher cheerio 0.877
Acsl Acyl-CoA synthetase long-chain 0.877
ttk tramtrack 0.877
sn singed 0.874
Hop Hsp70/Hsp90 organizing protein homolog 0.865
par-6 CG5884 gene product from transcript CG5884-RA 0.864
tutl turtle 0.862
ato atonal 0.862
caz cabeza 0.860
Fak56D Focal Adhesion Kinase 0.860
kibra kibra ortholog 0.858
stumps CG31317 gene product from transcript CG31317-RC 0.858
slp1 sloppy paired 1 0.857
phl pole hole 0.856
Caki Calcium/calmodulin-dependent protein kinase 0.852
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.908
Pfn1 profilin 1 0.779
Fgfr2 fibroblast growth factor receptor 2 0.762
Col12a1 collagen, type XII, alpha 1 0.746
Lamc1 laminin, gamma 1 0.742
Flt1 FMS-related tyrosine kinase 1 0.679
Ccl4 chemokine (C-C motif) ligand 4 0.658
Socs3 suppressor of cytokine signaling 3 0.638
Prkcb protein kinase C, beta 0.631
Marcks myristoylated alanine rich protein kinase C substrate 0.610
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.583
Ednra endothelin receptor type A 0.567
Prrx1 paired related homeobox 1 0.549
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.534
Mapk3 mitogen activated protein kinase 3 0.525
Jak2 Janus kinase 2 0.515
Pde3a phosphodiesterase 3A, cGMP inhibited 0.513
Vav1 vav 1 guanine nucleotide exchange factor 0.507
Eln elastin 0.484
Fosl1 fos-like antigen 1 0.478
Irs1 insulin receptor substrate 1 0.474
Tgfbr2 transforming growth factor, beta receptor II 0.465
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.460
S1pr2 sphingosine-1-phosphate receptor 2 0.460
Il1b interleukin 1 beta 0.457
Smad7 SMAD family member 7 0.449
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.444
Sirpa signal-regulatory protein alpha 0.438
Nefl neurofilament, light polypeptide 0.433
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.411
Ptma prothymosin alpha 0.410
Slit3 slit homolog 3 (Drosophila) 0.407
Gnrhr gonadotropin releasing hormone receptor 0.397
Sox17 SRY (sex determining region Y)-box 17 0.396
Tgfbr3 transforming growth factor, beta receptor III 0.395
Tcf4 transcription factor 4 0.392
Ccl3 chemokine (C-C motif) ligand 3 0.384
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.384
Itga6 integrin, alpha 6 0.377
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.377
Timp3 TIMP metallopeptidase inhibitor 3 0.376
Plagl1 pleiomorphic adenoma gene-like 1 0.376
Cga glycoprotein hormones, alpha polypeptide 0.370
Calcb calcitonin-related polypeptide, beta 0.364
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.361
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.357
Cd44 Cd44 molecule 0.349
Nfia nuclear factor I/A 0.348
Kitlg KIT ligand 0.347
Kcnmb1 potassium large conductance calcium-activated channel, subfamily M, beta member 1 0.343
Map2 microtubule-associated protein 2 0.341
Ptafr platelet-activating factor receptor 0.340
Dmd dystrophin 0.338
Abi3 ABI family, member 3 0.336
Ccr5 chemokine (C-C motif) receptor 5 0.335
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.334
Plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.333
Robo1 roundabout homolog 1 (Drosophila) 0.333
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.330
Rac1 ras-related C3 botulinum toxin substrate 1 0.329
Cpxm2 carboxypeptidase X (M14 family), member 2 0.329
Gja5 gap junction protein, alpha 5 0.329
Plek pleckstrin 0.329
Ppyr1 pancreatic polypeptide receptor 1 0.328
Clic4 chloride intracellular channel 4 0.328
Aqp5 aquaporin 5 0.324
Bcl2 B-cell CLL/lymphoma 2 0.321
Il1r1 interleukin 1 receptor, type I 0.320
Mmp2 matrix metallopeptidase 2 0.317
Csf1r colony stimulating factor 1 receptor 0.317
Grm5 glutamate receptor, metabotropic 5 0.316
Dchs1 dachsous 1 (Drosophila) 0.313
Vcan versican 0.312
Sell selectin L 0.312
Nfasc neurofascin 0.312
Acvr1 activin A receptor, type I 0.311
Inpp5d inositol polyphosphate-5-phosphatase D 0.307
Bmp1 bone morphogenetic protein 1 0.307
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.305
Ednrb endothelin receptor type B 0.302
Epas1 endothelial PAS domain protein 1 0.301
Fgfr1 Fibroblast growth factor receptor 1 0.296
Fcgrt Fc fragment of IgG, receptor, transporter, alpha 0.294
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.293
Myo1c myosin IC 0.293
Hck hemopoietic cell kinase 0.290
Sele selectin E 0.289
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.287
Nrg1 neuregulin 1 0.287
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.286
Foxi2 forkhead box I2 0.283
Trim47 tripartite motif-containing 47 0.278
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.277
Edn1 endothelin 1 0.276
Anxa1 annexin A1 0.275
Pecam1 platelet/endothelial cell adhesion molecule 1 0.273
Hoxa2 homeo box A2 0.271
Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 0.271
Reg3b regenerating islet-derived 3 beta 0.270
Vwa1 von Willebrand factor A domain containing 1 0.267
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism