Saccharomyces cerevisiae

19 known processes

VPS60 (YDR486C)

Vps60p

(Aliases: CHM5,MOS10)

VPS60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 181 0.815
vacuolar transport GO:0007034 145 0.690
cellular macromolecule catabolic process GO:0044265 363 0.664
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.608
modification dependent macromolecule catabolic process GO:0043632 203 0.574
modification dependent protein catabolic process GO:0019941 181 0.541
macromolecule catabolic process GO:0009057 383 0.472
cellular protein catabolic process GO:0044257 213 0.423
protein localization to organelle GO:0033365 337 0.404
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.394
protein catabolic process GO:0030163 221 0.381
proteolysis GO:0006508 268 0.360
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.336
organic cyclic compound catabolic process GO:1901361 499 0.320
vesicle mediated transport GO:0016192 335 0.288
Fly
vacuole organization GO:0007033 75 0.247
negative regulation of biosynthetic process GO:0009890 312 0.208
protein complex assembly GO:0006461 302 0.200
establishment of protein localization to organelle GO:0072594 278 0.193
protein transport GO:0015031 345 0.184
establishment of protein localization GO:0045184 367 0.165
regulation of proteolysis GO:0030162 44 0.163
late endosome to vacuole transport GO:0045324 42 0.163
establishment of protein localization to vacuole GO:0072666 91 0.159
nucleobase containing compound catabolic process GO:0034655 479 0.158
cellular nitrogen compound catabolic process GO:0044270 494 0.153
single organism cellular localization GO:1902580 375 0.149
endosomal transport GO:0016197 86 0.148
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.147
cellular homeostasis GO:0019725 138 0.143
aromatic compound catabolic process GO:0019439 491 0.137
guanosine containing compound metabolic process GO:1901068 111 0.136
single organism signaling GO:0044700 208 0.134
Fly
single organism catabolic process GO:0044712 619 0.134
organic hydroxy compound metabolic process GO:1901615 125 0.131
regulation of phosphorus metabolic process GO:0051174 230 0.123
heterocycle catabolic process GO:0046700 494 0.120
organelle fusion GO:0048284 85 0.113
protein localization to vacuole GO:0072665 92 0.113
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.110
cellular ion homeostasis GO:0006873 112 0.106
response to chemical GO:0042221 390 0.104
negative regulation of transcription dna templated GO:0045892 258 0.102
lipid metabolic process GO:0006629 269 0.100
carbohydrate derivative catabolic process GO:1901136 339 0.098
negative regulation of macromolecule metabolic process GO:0010605 375 0.094
ion homeostasis GO:0050801 118 0.092
regulation of biological quality GO:0065008 391 0.092
cation homeostasis GO:0055080 105 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.089
nucleoside phosphate catabolic process GO:1901292 331 0.089
protein targeting GO:0006605 272 0.086
cellular cation homeostasis GO:0030003 100 0.085
cell wall organization or biogenesis GO:0071554 190 0.082
nucleoside catabolic process GO:0009164 335 0.081
alcohol metabolic process GO:0006066 112 0.080
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.077
positive regulation of phosphorus metabolic process GO:0010562 147 0.074
organophosphate catabolic process GO:0046434 338 0.073
purine nucleoside catabolic process GO:0006152 330 0.073
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.073
protein complex biogenesis GO:0070271 314 0.073
negative regulation of cellular metabolic process GO:0031324 407 0.071
regulation of protein catabolic process GO:0042176 40 0.070
signal transduction GO:0007165 208 0.069
Fly
purine containing compound catabolic process GO:0072523 332 0.068
regulation of catalytic activity GO:0050790 307 0.068
positive regulation of hydrolase activity GO:0051345 112 0.067
negative regulation of nucleic acid templated transcription GO:1903507 260 0.065
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.065
regulation of cellular component organization GO:0051128 334 0.064
Fly
regulation of cellular catabolic process GO:0031329 195 0.063
negative regulation of rna biosynthetic process GO:1902679 260 0.062
gtp catabolic process GO:0006184 107 0.062
cellular protein complex assembly GO:0043623 209 0.062
positive regulation of macromolecule metabolic process GO:0010604 394 0.061
regulation of protein localization GO:0032880 62 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.059
homeostatic process GO:0042592 227 0.058
single organism membrane fusion GO:0044801 71 0.058
carbohydrate derivative metabolic process GO:1901135 549 0.058
intracellular signal transduction GO:0035556 112 0.058
Fly
negative regulation of cellular biosynthetic process GO:0031327 312 0.058
response to nutrient levels GO:0031667 150 0.058
negative regulation of rna metabolic process GO:0051253 262 0.058
positive regulation of biosynthetic process GO:0009891 336 0.056
regulation of localization GO:0032879 127 0.055
Fly
positive regulation of molecular function GO:0044093 185 0.055
protein ubiquitination GO:0016567 118 0.055
guanosine containing compound catabolic process GO:1901069 109 0.051
regulation of molecular function GO:0065009 320 0.050
purine nucleotide metabolic process GO:0006163 376 0.050
glycosyl compound catabolic process GO:1901658 335 0.050
cellular response to nutrient levels GO:0031669 144 0.050
developmental process involved in reproduction GO:0003006 159 0.049
Fly
signaling GO:0023052 208 0.049
Fly
organophosphate metabolic process GO:0019637 597 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.048
regulation of purine nucleotide metabolic process GO:1900542 109 0.047
reproductive process GO:0022414 248 0.047
Fly
cell differentiation GO:0030154 161 0.047
Fly
rna catabolic process GO:0006401 118 0.046
vesicle organization GO:0016050 68 0.046
positive regulation of catalytic activity GO:0043085 178 0.046
regulation of hydrolase activity GO:0051336 133 0.045
lipid biosynthetic process GO:0008610 170 0.044
sterol biosynthetic process GO:0016126 35 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.042
nuclear division GO:0000280 263 0.042
regulation of cell division GO:0051302 113 0.041
glycerolipid metabolic process GO:0046486 108 0.041
gene silencing GO:0016458 151 0.041
positive regulation of nucleic acid templated transcription GO:1903508 286 0.040
intracellular protein transport GO:0006886 319 0.040
meiotic nuclear division GO:0007126 163 0.039
mitotic cell cycle phase transition GO:0044772 141 0.038
endocytosis GO:0006897 90 0.038
Fly
ribonucleoside metabolic process GO:0009119 389 0.038
golgi vesicle transport GO:0048193 188 0.038
cell communication GO:0007154 345 0.038
Fly
anatomical structure morphogenesis GO:0009653 160 0.036
Fly
response to starvation GO:0042594 96 0.036
nucleoside triphosphate catabolic process GO:0009143 329 0.036
cellular developmental process GO:0048869 191 0.035
Fly
organelle fission GO:0048285 272 0.034
steroid metabolic process GO:0008202 47 0.034
meiotic cell cycle GO:0051321 272 0.033
nucleoside metabolic process GO:0009116 394 0.033
regulation of catabolic process GO:0009894 199 0.032
negative regulation of gene expression GO:0010629 312 0.032
organelle localization GO:0051640 128 0.032
ribonucleoside catabolic process GO:0042454 332 0.032
purine nucleoside triphosphate catabolic process GO:0009146 329 0.032
positive regulation of cellular protein metabolic process GO:0032270 89 0.032
maintenance of location GO:0051235 66 0.032
ribose phosphate metabolic process GO:0019693 384 0.032
membrane organization GO:0061024 276 0.031
cellular response to external stimulus GO:0071496 150 0.031
regulation of organelle organization GO:0033043 243 0.031
regulation of ras protein signal transduction GO:0046578 47 0.029
regulation of protein complex assembly GO:0043254 77 0.029
protein targeting to vacuole GO:0006623 91 0.029
positive regulation of cellular component organization GO:0051130 116 0.029
Fly
cellular response to extracellular stimulus GO:0031668 150 0.029
gtp metabolic process GO:0046039 107 0.029
cellular lipid metabolic process GO:0044255 229 0.029
negative regulation of gene expression epigenetic GO:0045814 147 0.029
regulation of cell communication GO:0010646 124 0.028
Fly
regulation of cellular component biogenesis GO:0044087 112 0.028
regulation of nucleotide catabolic process GO:0030811 106 0.028
filamentous growth GO:0030447 124 0.028
sporulation GO:0043934 132 0.028
cellular response to starvation GO:0009267 90 0.027
mitotic cell cycle GO:0000278 306 0.027
regulation of proteasomal protein catabolic process GO:0061136 34 0.027
single organism reproductive process GO:0044702 159 0.027
Fly
sporulation resulting in formation of a cellular spore GO:0030435 129 0.027
regulation of phosphate metabolic process GO:0019220 230 0.026
cellular metal ion homeostasis GO:0006875 78 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.025
cellular response to anoxia GO:0071454 3 0.025
nucleotide catabolic process GO:0009166 330 0.025
phospholipid biosynthetic process GO:0008654 89 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.024
single organism developmental process GO:0044767 258 0.024
Fly
purine ribonucleoside catabolic process GO:0046130 330 0.024
regulation of growth GO:0040008 50 0.024
positive regulation of rna metabolic process GO:0051254 294 0.024
fungal type cell wall biogenesis GO:0009272 80 0.024
establishment of protein localization to membrane GO:0090150 99 0.023
regulation of cell cycle process GO:0010564 150 0.023
vacuole fusion GO:0097576 40 0.023
rrna metabolic process GO:0016072 244 0.023
positive regulation of gene expression GO:0010628 321 0.023
cytoskeleton organization GO:0007010 230 0.023
regulation of nucleoside metabolic process GO:0009118 106 0.022
regulation of anatomical structure size GO:0090066 50 0.022
cellular response to dna damage stimulus GO:0006974 287 0.022
protein deubiquitination GO:0016579 17 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
sexual reproduction GO:0019953 216 0.021
Fly
positive regulation of transcription dna templated GO:0045893 286 0.021
chemical homeostasis GO:0048878 137 0.021
cellular amino acid metabolic process GO:0006520 225 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 27 0.021
fungal type cell wall organization GO:0031505 145 0.021
response to anoxia GO:0034059 3 0.021
reproductive process in single celled organism GO:0022413 145 0.021
protein targeting to membrane GO:0006612 52 0.021
purine ribonucleotide catabolic process GO:0009154 327 0.021
organelle inheritance GO:0048308 51 0.021
response to abiotic stimulus GO:0009628 159 0.021
dephosphorylation GO:0016311 127 0.020
cellular chemical homeostasis GO:0055082 123 0.020
sterol metabolic process GO:0016125 47 0.020
reproduction of a single celled organism GO:0032505 191 0.020
regulation of response to stimulus GO:0048583 157 0.020
Fly
regulation of cellular protein catabolic process GO:1903362 36 0.020
nucleobase containing small molecule metabolic process GO:0055086 491 0.019
localization within membrane GO:0051668 29 0.019
regulation of protein metabolic process GO:0051246 237 0.019
regulation of dna repair GO:0006282 14 0.019
positive regulation of gtp catabolic process GO:0033126 80 0.019
single organism carbohydrate metabolic process GO:0044723 237 0.019
cell wall biogenesis GO:0042546 93 0.019
anatomical structure development GO:0048856 160 0.019
Fly
positive regulation of cell death GO:0010942 3 0.019
cellular carbohydrate metabolic process GO:0044262 135 0.019
positive regulation of nucleotide metabolic process GO:0045981 101 0.018
purine ribonucleotide metabolic process GO:0009150 372 0.018
regulation of purine nucleotide catabolic process GO:0033121 106 0.018
vacuole fusion non autophagic GO:0042144 40 0.018
cell division GO:0051301 205 0.018
positive regulation of programmed cell death GO:0043068 3 0.018
anatomical structure formation involved in morphogenesis GO:0048646 136 0.018
Fly
ribonucleoside triphosphate catabolic process GO:0009203 327 0.018
regulation of nucleotide metabolic process GO:0006140 110 0.018
alcohol biosynthetic process GO:0046165 75 0.018
protein modification by small protein conjugation or removal GO:0070647 172 0.018
multi organism reproductive process GO:0044703 216 0.018
Fly
negative regulation of cell cycle process GO:0010948 86 0.017
positive regulation of catabolic process GO:0009896 135 0.017
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.017
organic hydroxy compound biosynthetic process GO:1901617 81 0.017
ribonucleotide catabolic process GO:0009261 327 0.017
cofactor biosynthetic process GO:0051188 80 0.017
sexual sporulation GO:0034293 113 0.017
developmental process GO:0032502 261 0.017
Fly
cell development GO:0048468 107 0.017
Fly
negative regulation of cell division GO:0051782 66 0.016
regulation of gene expression epigenetic GO:0040029 147 0.016
purine nucleotide catabolic process GO:0006195 328 0.016
maintenance of protein location GO:0045185 53 0.016
phospholipid metabolic process GO:0006644 125 0.016
carboxylic acid biosynthetic process GO:0046394 152 0.015
organonitrogen compound catabolic process GO:1901565 404 0.015
regulation of small gtpase mediated signal transduction GO:0051056 47 0.015
response to extracellular stimulus GO:0009991 156 0.015
purine nucleoside metabolic process GO:0042278 380 0.015
chromatin remodeling GO:0006338 80 0.015
protein modification by small protein conjugation GO:0032446 144 0.015
cellular response to chemical stimulus GO:0070887 315 0.014
proteasomal protein catabolic process GO:0010498 141 0.014
negative regulation of response to stimulus GO:0048585 40 0.014
Fly
carboxylic acid metabolic process GO:0019752 338 0.014
organophosphate biosynthetic process GO:0090407 182 0.014
ribonucleoside triphosphate metabolic process GO:0009199 356 0.014
double strand break repair GO:0006302 105 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.013
regulation of signaling GO:0023051 119 0.013
Fly
dna repair GO:0006281 236 0.013
regulation of cellular component size GO:0032535 50 0.013
regulation of developmental process GO:0050793 30 0.013
protein processing GO:0016485 64 0.013
multi organism process GO:0051704 233 0.013
Fly
positive regulation of apoptotic process GO:0043065 3 0.013
glycerophospholipid biosynthetic process GO:0046474 68 0.013
regulation of transport GO:0051049 85 0.013
Fly
cell growth GO:0016049 89 0.013
ribonucleotide metabolic process GO:0009259 377 0.013
positive regulation of cellular biosynthetic process GO:0031328 336 0.013
vacuolar acidification GO:0007035 16 0.013
positive regulation of cellular catabolic process GO:0031331 128 0.013
meiotic cell cycle process GO:1903046 229 0.012
purine containing compound metabolic process GO:0072521 400 0.012
regulation of signal transduction GO:0009966 114 0.012
Fly
ras protein signal transduction GO:0007265 29 0.012
organelle assembly GO:0070925 118 0.012
intralumenal vesicle formation GO:0070676 7 0.012
regulation of cellular protein metabolic process GO:0032268 232 0.012
protein maturation GO:0051604 76 0.012
nucleotide metabolic process GO:0009117 453 0.012
ph reduction GO:0045851 16 0.012
carbohydrate derivative biosynthetic process GO:1901137 181 0.011
mitotic nuclear division GO:0007067 131 0.011
positive regulation of nucleotide catabolic process GO:0030813 97 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 12 0.011
nucleoside triphosphate metabolic process GO:0009141 364 0.011
purine ribonucleoside metabolic process GO:0046128 380 0.011
cellular response to oxidative stress GO:0034599 94 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.010
positive regulation of gtpase activity GO:0043547 80 0.010
positive regulation of secretion GO:0051047 2 0.010
small molecule biosynthetic process GO:0044283 258 0.010
intracellular ph reduction GO:0051452 16 0.010
nuclear transcribed mrna catabolic process GO:0000956 89 0.010

VPS60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org