Saccharomyces cerevisiae

18 known processes

RPL12A (YEL054C)

Rpl12ap

RPL12A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribosome biogenesis GO:0042254 335 0.919
maturation of ssu rrna GO:0030490 105 0.903
rrna processing GO:0006364 227 0.653
ncrna processing GO:0034470 330 0.621
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 96 0.579
ribosomal small subunit biogenesis GO:0042274 124 0.477
rrna metabolic process GO:0016072 244 0.430
mitotic cell cycle GO:0000278 306 0.330
mitotic cell cycle process GO:1903047 294 0.256
ribosome assembly GO:0042255 57 0.228
ribonucleoprotein complex subunit organization GO:0071826 152 0.211
nuclear transport GO:0051169 165 0.203
ribonucleoprotein complex assembly GO:0022618 143 0.174
spindle organization GO:0007051 37 0.159
organelle assembly GO:0070925 118 0.153
regulation of biological quality GO:0065008 391 0.146
maturation of 5 8s rrna GO:0000460 80 0.128
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 47 0.119
nucleocytoplasmic transport GO:0006913 163 0.106
nucleobase containing compound transport GO:0015931 124 0.099
rna phosphodiester bond hydrolysis GO:0090501 112 0.085
mitotic spindle organization GO:0007052 30 0.074
positive regulation of rna biosynthetic process GO:1902680 286 0.072
negative regulation of gene expression GO:0010629 312 0.072
nuclear export GO:0051168 124 0.071
nucleobase containing compound catabolic process GO:0034655 479 0.065
endonucleolytic cleavage involved in rrna processing GO:0000478 47 0.065
regulation of protein metabolic process GO:0051246 237 0.064
heterocycle catabolic process GO:0046700 494 0.062
establishment of protein localization GO:0045184 367 0.057
phosphorylation GO:0016310 291 0.057
ribosomal large subunit assembly GO:0000027 35 0.057
nitrogen compound transport GO:0071705 212 0.057
cytoskeleton organization GO:0007010 230 0.057
microtubule based process GO:0007017 117 0.057
single organism developmental process GO:0044767 258 0.057
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.056
rna transport GO:0050658 92 0.054
positive regulation of gene expression GO:0010628 321 0.054
ribosomal large subunit biogenesis GO:0042273 98 0.053
regulation of protein kinase activity GO:0045859 67 0.051
positive regulation of cellular biosynthetic process GO:0031328 336 0.051
response to external stimulus GO:0009605 158 0.050
regulation of phosphorylation GO:0042325 86 0.050
rrna transport GO:0051029 18 0.050
homeostatic process GO:0042592 227 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.049
regulation of cell cycle GO:0051726 195 0.049
regulation of protein phosphorylation GO:0001932 75 0.049
cellular nitrogen compound catabolic process GO:0044270 494 0.049
positive regulation of biosynthetic process GO:0009891 336 0.048
endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000447 43 0.048
aromatic compound catabolic process GO:0019439 491 0.046
positive regulation of phosphorus metabolic process GO:0010562 147 0.045
cellular chemical homeostasis GO:0055082 123 0.044
cell communication GO:0007154 345 0.043
carbohydrate derivative metabolic process GO:1901135 549 0.043
rna 3 end processing GO:0031123 88 0.042
protein phosphorylation GO:0006468 197 0.042
regulation of molecular function GO:0065009 320 0.042
response to extracellular stimulus GO:0009991 156 0.042
protein complex assembly GO:0006461 302 0.041
rna export from nucleus GO:0006405 88 0.041
posttranscriptional regulation of gene expression GO:0010608 115 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.040
regulation of cellular protein metabolic process GO:0032268 232 0.040
mitotic spindle elongation GO:0000022 14 0.040
positive regulation of macromolecule metabolic process GO:0010604 394 0.039
single organism catabolic process GO:0044712 619 0.039
cellular ion homeostasis GO:0006873 112 0.039
rrna export from nucleus GO:0006407 18 0.038
protein transport GO:0015031 345 0.038
organophosphate metabolic process GO:0019637 597 0.038
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.038
nucleic acid transport GO:0050657 94 0.037
organic cyclic compound catabolic process GO:1901361 499 0.037
anatomical structure morphogenesis GO:0009653 160 0.036
microtubule cytoskeleton organization GO:0000226 109 0.036
establishment of rna localization GO:0051236 92 0.035
cleavage involved in rrna processing GO:0000469 69 0.035
negative regulation of cellular metabolic process GO:0031324 407 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.034
developmental process GO:0032502 261 0.034
cellular homeostasis GO:0019725 138 0.033
anatomical structure development GO:0048856 160 0.033
mrna processing GO:0006397 185 0.033
regulation of catalytic activity GO:0050790 307 0.033
regulation of cellular component organization GO:0051128 334 0.032
regulation of phosphate metabolic process GO:0019220 230 0.032
signal transduction GO:0007165 208 0.031
purine ribonucleotide metabolic process GO:0009150 372 0.031
intracellular protein transport GO:0006886 319 0.031
cytoplasmic translation GO:0002181 65 0.030
chemical homeostasis GO:0048878 137 0.030
ribosomal small subunit assembly GO:0000028 15 0.030
positive regulation of rna metabolic process GO:0051254 294 0.029
regulation of phosphorus metabolic process GO:0051174 230 0.029
multi organism process GO:0051704 233 0.029
positive regulation of molecular function GO:0044093 185 0.028
reproductive process GO:0022414 248 0.028
peptidyl amino acid modification GO:0018193 116 0.028
maintenance of location GO:0051235 66 0.027
signaling GO:0023052 208 0.027
positive regulation of transcription dna templated GO:0045893 286 0.027
purine containing compound metabolic process GO:0072521 400 0.027
glycosyl compound metabolic process GO:1901657 398 0.026
cell wall organization GO:0071555 146 0.026
developmental process involved in reproduction GO:0003006 159 0.026
regulation of cellular component biogenesis GO:0044087 112 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.026
regulation of kinase activity GO:0043549 71 0.026
response to chemical GO:0042221 390 0.026
ribose phosphate metabolic process GO:0019693 384 0.026
rna localization GO:0006403 112 0.026
ribonucleoside metabolic process GO:0009119 389 0.025
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.025
cellular response to dna damage stimulus GO:0006974 287 0.025
ncrna 3 end processing GO:0043628 44 0.024
nucleoside metabolic process GO:0009116 394 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
protein complex biogenesis GO:0070271 314 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.023
ion homeostasis GO:0050801 118 0.023
positive regulation of kinase activity GO:0033674 24 0.023
sexual reproduction GO:0019953 216 0.022
negative regulation of biosynthetic process GO:0009890 312 0.022
glycosyl compound catabolic process GO:1901658 335 0.022
ribonucleoprotein complex localization GO:0071166 46 0.022
external encapsulating structure organization GO:0045229 146 0.022
positive regulation of catalytic activity GO:0043085 178 0.022
cellular amino acid metabolic process GO:0006520 225 0.021
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.021
regulation of transferase activity GO:0051338 83 0.021
response to nutrient levels GO:0031667 150 0.021
negative regulation of macromolecule metabolic process GO:0010605 375 0.020
organonitrogen compound catabolic process GO:1901565 404 0.020
ascospore wall biogenesis GO:0070591 52 0.020
alpha amino acid metabolic process GO:1901605 124 0.020
nucleobase containing small molecule metabolic process GO:0055086 491 0.020
cellular ketone metabolic process GO:0042180 63 0.019
mrna metabolic process GO:0016071 269 0.019
rrna 3 end processing GO:0031125 22 0.019
growth GO:0040007 157 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.019
reproductive process in single celled organism GO:0022413 145 0.019
positive regulation of protein modification process GO:0031401 49 0.019
positive regulation of phosphate metabolic process GO:0045937 147 0.018
negative regulation of cellular biosynthetic process GO:0031327 312 0.018
regulation of protein modification process GO:0031399 110 0.018
single organism signaling GO:0044700 208 0.018
meiotic cell cycle GO:0051321 272 0.018
positive regulation of transferase activity GO:0051347 28 0.018
carbohydrate derivative catabolic process GO:1901136 339 0.017
regulation of response to stimulus GO:0048583 157 0.017
multi organism reproductive process GO:0044703 216 0.017
vesicle mediated transport GO:0016192 335 0.017
purine nucleoside triphosphate catabolic process GO:0009146 329 0.017
cellular response to nutrient levels GO:0031669 144 0.017
regulation of cellular catabolic process GO:0031329 195 0.017
ribosomal subunit export from nucleus GO:0000054 46 0.017
oxidation reduction process GO:0055114 353 0.017
nucleoside triphosphate metabolic process GO:0009141 364 0.017
purine nucleoside triphosphate metabolic process GO:0009144 356 0.016
rna splicing GO:0008380 131 0.016
regulation of rna splicing GO:0043484 3 0.016
establishment of ribosome localization GO:0033753 46 0.016
cellular response to external stimulus GO:0071496 150 0.016
gene silencing GO:0016458 151 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.016
negative regulation of cellular component organization GO:0051129 109 0.016
cell cycle phase transition GO:0044770 144 0.016
ribosome localization GO:0033750 46 0.016
fungal type cell wall organization GO:0031505 145 0.015
positive regulation of phosphorylation GO:0042327 33 0.015
organonitrogen compound biosynthetic process GO:1901566 314 0.015
cellular response to extracellular stimulus GO:0031668 150 0.015
protein targeting GO:0006605 272 0.015
ribonucleoside triphosphate metabolic process GO:0009199 356 0.015
single organism reproductive process GO:0044702 159 0.015
organophosphate biosynthetic process GO:0090407 182 0.014
regulation of translation GO:0006417 89 0.014
purine ribonucleoside catabolic process GO:0046130 330 0.014
cell death GO:0008219 30 0.014
organelle localization GO:0051640 128 0.014
spindle elongation GO:0051231 14 0.014
cellular response to chemical stimulus GO:0070887 315 0.014
purine nucleoside monophosphate metabolic process GO:0009126 262 0.014
purine nucleoside metabolic process GO:0042278 380 0.014
ribonucleoprotein complex export from nucleus GO:0071426 46 0.014
response to organic substance GO:0010033 182 0.014
organic acid metabolic process GO:0006082 352 0.013
sporulation GO:0043934 132 0.013
nuclear division GO:0000280 263 0.013
nucleoside catabolic process GO:0009164 335 0.013
programmed cell death GO:0012501 30 0.013
cellular protein catabolic process GO:0044257 213 0.013
positive regulation of protein metabolic process GO:0051247 93 0.013
positive regulation of cellular protein metabolic process GO:0032270 89 0.013
ribonucleotide metabolic process GO:0009259 377 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
regulation of cell cycle process GO:0010564 150 0.012
nucleoside triphosphate catabolic process GO:0009143 329 0.012
nucleoside phosphate catabolic process GO:1901292 331 0.012
phospholipid biosynthetic process GO:0008654 89 0.012
regulation of signal transduction GO:0009966 114 0.012
purine ribonucleoside metabolic process GO:0046128 380 0.012
negative regulation of rna metabolic process GO:0051253 262 0.012
regulation of cellular response to stress GO:0080135 50 0.012
endocytosis GO:0006897 90 0.012
translational initiation GO:0006413 56 0.012
cellular cation homeostasis GO:0030003 100 0.012
cellular macromolecule catabolic process GO:0044265 363 0.011
negative regulation of mitotic cell cycle GO:0045930 63 0.011
purine nucleoside catabolic process GO:0006152 330 0.011
meiotic nuclear division GO:0007126 163 0.011
macromolecule catabolic process GO:0009057 383 0.011
dna replication GO:0006260 147 0.011
single organism cellular localization GO:1902580 375 0.011
ascospore formation GO:0030437 107 0.011
organelle fission GO:0048285 272 0.010
cellular developmental process GO:0048869 191 0.010
positive regulation of nucleic acid templated transcription GO:1903508 286 0.010
regulation of dna metabolic process GO:0051052 100 0.010
mitochondrion organization GO:0007005 261 0.010
regulation of catabolic process GO:0009894 199 0.010
positive regulation of cell cycle GO:0045787 32 0.010
ribonucleoside triphosphate catabolic process GO:0009203 327 0.010

RPL12A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
congenital hypoplastic anemia DOID:1342 0 0.017
immune system disease DOID:2914 0 0.017
diamond blackfan anemia DOID:1339 0 0.017
aplastic anemia DOID:12449 0 0.017
bone marrow disease DOID:4961 0 0.017
anemia DOID:2355 0 0.017
hematopoietic system disease DOID:74 0 0.017