Saccharomyces cerevisiae

20 known processes

MDH1 (YKL085W)

Mdh1p

MDH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
energy derivation by oxidation of organic compounds GO:0015980 125 0.964
coenzyme metabolic process GO:0006732 104 0.768
oxidation reduction process GO:0055114 353 0.673
cofactor metabolic process GO:0051186 126 0.650
nucleotide metabolic process GO:0009117 453 0.615
generation of precursor metabolites and energy GO:0006091 147 0.600
organophosphate metabolic process GO:0019637 597 0.556
cellular protein complex assembly GO:0043623 209 0.444
mitochondrial electron transport ubiquinol to cytochrome c GO:0006122 11 0.431
aerobic respiration GO:0009060 55 0.421
nucleoside phosphate metabolic process GO:0006753 458 0.357
nicotinamide nucleotide metabolic process GO:0046496 44 0.315
oxidoreduction coenzyme metabolic process GO:0006733 58 0.272
cellular respiration GO:0045333 82 0.271
atp synthesis coupled electron transport GO:0042773 25 0.256
tricarboxylic acid metabolic process GO:0072350 3 0.233
cytochrome complex assembly GO:0017004 29 0.229
nadh metabolic process GO:0006734 12 0.204
nucleobase containing small molecule metabolic process GO:0055086 491 0.191
monocarboxylic acid metabolic process GO:0032787 122 0.185
pyridine nucleotide metabolic process GO:0019362 45 0.183
purine ribonucleoside triphosphate biosynthetic process GO:0009206 17 0.181
protein complex assembly GO:0006461 302 0.178
mitochondrial atp synthesis coupled electron transport GO:0042775 25 0.177
translation GO:0006412 230 0.159
nucleoside triphosphate metabolic process GO:0009141 364 0.150
ribonucleoside metabolic process GO:0009119 389 0.147
dicarboxylic acid metabolic process GO:0043648 20 0.145
glycosyl compound metabolic process GO:1901657 398 0.144
oxoacid metabolic process GO:0043436 351 0.143
nucleoside monophosphate metabolic process GO:0009123 267 0.142
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.136
tricarboxylic acid cycle GO:0006099 6 0.133
purine ribonucleotide metabolic process GO:0009150 372 0.129
carbohydrate derivative metabolic process GO:1901135 549 0.128
organic acid metabolic process GO:0006082 352 0.124
acyl coa metabolic process GO:0006637 13 0.115
ribonucleotide metabolic process GO:0009259 377 0.114
detection of glucose GO:0051594 3 0.111
response to organic cyclic compound GO:0014070 1 0.111
regulation of cellular component organization GO:0051128 334 0.106
cellular nitrogen compound catabolic process GO:0044270 494 0.105
electron transport chain GO:0022900 25 0.105
transmembrane transport GO:0055085 349 0.100
developmental process GO:0032502 261 0.099
cell aging GO:0007569 70 0.089
purine ribonucleoside metabolic process GO:0046128 380 0.082
protein complex biogenesis GO:0070271 314 0.079
regulation of phosphate metabolic process GO:0019220 230 0.075
cellular amine metabolic process GO:0044106 51 0.075
mitochondrial translation GO:0032543 52 0.074
hydrogen ion transmembrane transport GO:1902600 49 0.073
ribose phosphate metabolic process GO:0019693 384 0.072
nucleotide biosynthetic process GO:0009165 79 0.072
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.069
single organism catabolic process GO:0044712 619 0.067
regulation of meiotic cell cycle GO:0051445 43 0.066
aromatic compound catabolic process GO:0019439 491 0.066
nucleoside triphosphate catabolic process GO:0009143 329 0.066
respiratory electron transport chain GO:0022904 25 0.066
thioester metabolic process GO:0035383 13 0.065
negative regulation of protein metabolic process GO:0051248 85 0.065
cellular response to chemical stimulus GO:0070887 315 0.064
regulation of cellular amine metabolic process GO:0033238 21 0.064
single organism membrane organization GO:0044802 275 0.063
heterocycle catabolic process GO:0046700 494 0.062
amine metabolic process GO:0009308 51 0.062
purine nucleoside triphosphate metabolic process GO:0009144 356 0.061
protein transmembrane transport GO:0071806 82 0.061
purine nucleoside monophosphate metabolic process GO:0009126 262 0.060
negative regulation of cellular protein metabolic process GO:0032269 85 0.059
pyridine containing compound metabolic process GO:0072524 53 0.058
response to chemical GO:0042221 390 0.058
organophosphate biosynthetic process GO:0090407 182 0.057
regulation of phosphorus metabolic process GO:0051174 230 0.057
regulation of translation GO:0006417 89 0.055
branched chain amino acid metabolic process GO:0009081 16 0.054
nad metabolic process GO:0019674 25 0.054
response to organic substance GO:0010033 182 0.053
ribonucleotide catabolic process GO:0009261 327 0.053
gtp metabolic process GO:0046039 107 0.053
purine nucleotide metabolic process GO:0006163 376 0.052
mitochondrial genome maintenance GO:0000002 40 0.052
protein transport GO:0015031 345 0.051
detection of hexose stimulus GO:0009732 3 0.049
negative regulation of organelle organization GO:0010639 103 0.049
single organism developmental process GO:0044767 258 0.048
carbohydrate metabolic process GO:0005975 252 0.047
protein dna complex subunit organization GO:0071824 153 0.047
purine nucleotide catabolic process GO:0006195 328 0.045
nucleotide catabolic process GO:0009166 330 0.045
ribonucleoside triphosphate catabolic process GO:0009203 327 0.045
regulation of cellular protein metabolic process GO:0032268 232 0.044
ribonucleoside triphosphate metabolic process GO:0009199 356 0.043
glucose metabolic process GO:0006006 65 0.043
nucleobase containing compound catabolic process GO:0034655 479 0.042
energy coupled proton transport down electrochemical gradient GO:0015985 17 0.042
phosphorylation GO:0016310 291 0.042
cofactor biosynthetic process GO:0051188 80 0.042
purine ribonucleoside catabolic process GO:0046130 330 0.042
positive regulation of apoptotic process GO:0043065 3 0.041
small molecule biosynthetic process GO:0044283 258 0.040
establishment of protein localization GO:0045184 367 0.040
developmental process involved in reproduction GO:0003006 159 0.039
mitochondrion organization GO:0007005 261 0.039
organonitrogen compound biosynthetic process GO:1901566 314 0.039
nucleoside catabolic process GO:0009164 335 0.037
purine nucleoside metabolic process GO:0042278 380 0.037
purine ribonucleotide catabolic process GO:0009154 327 0.037
organonitrogen compound catabolic process GO:1901565 404 0.037
reproductive process GO:0022414 248 0.037
carboxylic acid metabolic process GO:0019752 338 0.037
cellular amino acid biosynthetic process GO:0008652 118 0.036
purine containing compound catabolic process GO:0072523 332 0.036
chromatin silencing at rdna GO:0000183 32 0.036
ribonucleoside monophosphate metabolic process GO:0009161 265 0.035
detection of monosaccharide stimulus GO:0034287 3 0.035
negative regulation of macromolecule metabolic process GO:0010605 375 0.035
cellular developmental process GO:0048869 191 0.034
atp metabolic process GO:0046034 251 0.034
cytoplasmic translation GO:0002181 65 0.034
inorganic ion transmembrane transport GO:0098660 109 0.034
nucleoside metabolic process GO:0009116 394 0.033
purine containing compound metabolic process GO:0072521 400 0.033
macromolecular complex disassembly GO:0032984 80 0.033
nucleoside phosphate biosynthetic process GO:1901293 80 0.033
regulation of molecular function GO:0065009 320 0.032
purine nucleoside catabolic process GO:0006152 330 0.032
organic cyclic compound catabolic process GO:1901361 499 0.032
aging GO:0007568 71 0.031
negative regulation of cellular component organization GO:0051129 109 0.031
negative regulation of cell cycle GO:0045786 91 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.031
purine nucleotide biosynthetic process GO:0006164 41 0.030
purine ribonucleoside monophosphate biosynthetic process GO:0009168 28 0.029
carbohydrate derivative catabolic process GO:1901136 339 0.028
organophosphate catabolic process GO:0046434 338 0.027
regulation of catalytic activity GO:0050790 307 0.027
sulfur compound metabolic process GO:0006790 95 0.027
negative regulation of cell cycle process GO:0010948 86 0.027
negative regulation of protein modification process GO:0031400 37 0.026
ribonucleoside catabolic process GO:0042454 332 0.026
cellular response to organic substance GO:0071310 159 0.026
regulation of generation of precursor metabolites and energy GO:0043467 23 0.025
regulation of protein metabolic process GO:0051246 237 0.025
cell differentiation GO:0030154 161 0.025
nuclear export GO:0051168 124 0.025
mitochondrial respiratory chain complex assembly GO:0033108 36 0.025
carbon catabolite activation of transcription GO:0045991 26 0.024
cellular ketone metabolic process GO:0042180 63 0.023
glycosyl compound catabolic process GO:1901658 335 0.023
regulation of signaling GO:0023051 119 0.023
regulation of dna replication GO:0006275 51 0.023
purine containing compound biosynthetic process GO:0072522 53 0.022
regulation of cell cycle process GO:0010564 150 0.022
response to extracellular stimulus GO:0009991 156 0.022
carboxylic acid biosynthetic process GO:0046394 152 0.021
positive regulation of cellular component organization GO:0051130 116 0.021
response to external stimulus GO:0009605 158 0.021
alcohol biosynthetic process GO:0046165 75 0.021
positive regulation of phosphorus metabolic process GO:0010562 147 0.020
positive regulation of rna metabolic process GO:0051254 294 0.020
single organism cellular localization GO:1902580 375 0.020
regulation of catabolic process GO:0009894 199 0.020
nucleoside triphosphate biosynthetic process GO:0009142 22 0.020
carbon catabolite regulation of transcription GO:0045990 39 0.020
tetrapyrrole biosynthetic process GO:0033014 14 0.020
mitochondrial respiratory chain complex iv biogenesis GO:0097034 26 0.020
phospholipid metabolic process GO:0006644 125 0.020
cellular amino acid metabolic process GO:0006520 225 0.019
intracellular protein transmembrane import GO:0044743 67 0.019
organelle localization GO:0051640 128 0.019
purine ribonucleotide biosynthetic process GO:0009152 39 0.018
inorganic cation transmembrane transport GO:0098662 98 0.018
covalent chromatin modification GO:0016569 119 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.018
regulation of protein modification process GO:0031399 110 0.017
regulation of transferase activity GO:0051338 83 0.017
protein maturation GO:0051604 76 0.017
mitochondrial respiratory chain complex iv assembly GO:0033617 18 0.017
negative regulation of biosynthetic process GO:0009890 312 0.017
posttranscriptional regulation of gene expression GO:0010608 115 0.017
glycerolipid metabolic process GO:0046486 108 0.017
tetrapyrrole metabolic process GO:0033013 15 0.017
regulation of meiosis GO:0040020 42 0.017
positive regulation of organelle organization GO:0010638 85 0.016
regulation of phosphorylation GO:0042325 86 0.016
regulation of nuclear division GO:0051783 103 0.016
cell morphogenesis GO:0000902 30 0.016
purine nucleoside monophosphate biosynthetic process GO:0009127 28 0.016
regulation of cellular catabolic process GO:0031329 195 0.016
establishment of protein localization to mitochondrion GO:0072655 63 0.016
chromatin organization GO:0006325 242 0.016
coenzyme biosynthetic process GO:0009108 66 0.016
positive regulation of protein metabolic process GO:0051247 93 0.015
organic hydroxy compound metabolic process GO:1901615 125 0.015
positive regulation of nucleotide metabolic process GO:0045981 101 0.015
regulation of organelle organization GO:0033043 243 0.015
negative regulation of phosphorus metabolic process GO:0010563 49 0.015
protein phosphorylation GO:0006468 197 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
regulation of nucleotide metabolic process GO:0006140 110 0.015
regulation of cellular amino acid metabolic process GO:0006521 16 0.015
positive regulation of cellular amine metabolic process GO:0033240 10 0.014
mitotic cell cycle process GO:1903047 294 0.014
ribonucleoprotein complex subunit organization GO:0071826 152 0.014
mitochondrial respiratory chain complex iii biogenesis GO:0097033 11 0.014
positive regulation of cell death GO:0010942 3 0.014
monosaccharide metabolic process GO:0005996 83 0.014
guanosine containing compound catabolic process GO:1901069 109 0.014
protein localization to plasma membrane GO:0072659 18 0.014
carbohydrate biosynthetic process GO:0016051 82 0.014
regulation of protein phosphorylation GO:0001932 75 0.014
nucleoside monophosphate biosynthetic process GO:0009124 33 0.014
regulation of cell cycle GO:0051726 195 0.014
cellular response to nutrient levels GO:0031669 144 0.014
cellular cation homeostasis GO:0030003 100 0.014
regulation of purine nucleotide metabolic process GO:1900542 109 0.014
regulation of nucleoside metabolic process GO:0009118 106 0.014
single organism reproductive process GO:0044702 159 0.014
anatomical structure homeostasis GO:0060249 74 0.013
cell cycle checkpoint GO:0000075 82 0.013
regulation of phosphatidylcholine biosynthetic process GO:2001245 7 0.013
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.013
ribonucleotide biosynthetic process GO:0009260 44 0.013
intracellular protein transport GO:0006886 319 0.013
rna transport GO:0050658 92 0.013
positive regulation of biosynthetic process GO:0009891 336 0.013
detection of chemical stimulus GO:0009593 3 0.013
cellular biogenic amine metabolic process GO:0006576 37 0.013
ribose phosphate biosynthetic process GO:0046390 50 0.013
positive regulation of molecular function GO:0044093 185 0.013
signal transduction GO:0007165 208 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.013
single organism carbohydrate metabolic process GO:0044723 237 0.013
protein localization to membrane GO:0072657 102 0.013
respiratory chain complex iv assembly GO:0008535 18 0.013
meiotic nuclear division GO:0007126 163 0.013
negative regulation of cellular metabolic process GO:0031324 407 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
positive regulation of intracellular protein transport GO:0090316 3 0.012
atp catabolic process GO:0006200 224 0.012
establishment of rna localization GO:0051236 92 0.012
positive regulation of secretion GO:0051047 2 0.012
nucleoside biosynthetic process GO:0009163 38 0.012
hexose metabolic process GO:0019318 78 0.012
negative regulation of transferase activity GO:0051348 31 0.012
divalent inorganic cation homeostasis GO:0072507 21 0.012
monovalent inorganic cation transport GO:0015672 78 0.012
pigment biosynthetic process GO:0046148 22 0.012
positive regulation of cellular biosynthetic process GO:0031328 336 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.012
positive regulation of gene expression GO:0010628 321 0.012
purine nucleoside triphosphate biosynthetic process GO:0009145 17 0.012
intracellular protein transmembrane transport GO:0065002 80 0.012
autophagy GO:0006914 106 0.012
protein localization to mitochondrion GO:0070585 63 0.012
leucine metabolic process GO:0006551 8 0.012
regulation of nucleotide catabolic process GO:0030811 106 0.012
response to oxidative stress GO:0006979 99 0.012
regulation of hydrolase activity GO:0051336 133 0.011
multi organism process GO:0051704 233 0.011
histone modification GO:0016570 119 0.011
rna localization GO:0006403 112 0.011
protein folding GO:0006457 94 0.011
regulation of mitochondrion organization GO:0010821 20 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
response to starvation GO:0042594 96 0.011
cellular homeostasis GO:0019725 138 0.011
regulation of cell division GO:0051302 113 0.011
replicative cell aging GO:0001302 46 0.011
homeostatic process GO:0042592 227 0.011
positive regulation of cellular protein metabolic process GO:0032270 89 0.011
alpha amino acid metabolic process GO:1901605 124 0.011
regulation of mitochondrial translation GO:0070129 15 0.011
phospholipid biosynthetic process GO:0008654 89 0.010
negative regulation of nuclear division GO:0051784 62 0.010
regulation of cellular respiration GO:0043457 7 0.010
cell communication GO:0007154 345 0.010
ribonucleoside monophosphate biosynthetic process GO:0009156 31 0.010
response to endogenous stimulus GO:0009719 26 0.010
anatomical structure development GO:0048856 160 0.010
positive regulation of cellular catabolic process GO:0031331 128 0.010
organic acid biosynthetic process GO:0016053 152 0.010

MDH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of anatomical entity DOID:7 0 0.014
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010