Saccharomyces cerevisiae

20 known processes

COA4 (YLR218C)

Coa4p

(Aliases: CMC3)

COA4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitochondrial respiratory chain complex assembly GO:0033108 36 0.921
cellular protein complex assembly GO:0043623 209 0.790
respiratory chain complex iv assembly GO:0008535 18 0.701
protein complex assembly GO:0006461 302 0.692
cytochrome complex assembly GO:0017004 29 0.491
mitochondrial respiratory chain complex iv assembly GO:0033617 18 0.410
mitochondrial respiratory chain complex iv biogenesis GO:0097034 26 0.389
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.284
protein complex biogenesis GO:0070271 314 0.271
positive regulation of rna metabolic process GO:0051254 294 0.260
negative regulation of biosynthetic process GO:0009890 312 0.255
negative regulation of cellular biosynthetic process GO:0031327 312 0.252
negative regulation of organelle organization GO:0010639 103 0.215
energy derivation by oxidation of organic compounds GO:0015980 125 0.197
regulation of cellular component organization GO:0051128 334 0.189
negative regulation of macromolecule metabolic process GO:0010605 375 0.170
regulation of organelle organization GO:0033043 243 0.169
positive regulation of transcription dna templated GO:0045893 286 0.160
generation of precursor metabolites and energy GO:0006091 147 0.154
transition metal ion transport GO:0000041 45 0.154
mitochondrion organization GO:0007005 261 0.142
negative regulation of gene expression GO:0010629 312 0.142
single organism carbohydrate metabolic process GO:0044723 237 0.138
positive regulation of gene expression GO:0010628 321 0.136
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.135
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.122
cellular carbohydrate metabolic process GO:0044262 135 0.118
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.117
oxidation reduction process GO:0055114 353 0.117
positive regulation of nucleic acid templated transcription GO:1903508 286 0.113
regulation of cellular ketone metabolic process GO:0010565 42 0.109
regulation of cellular protein metabolic process GO:0032268 232 0.103
regulation of protein metabolic process GO:0051246 237 0.103
lipid biosynthetic process GO:0008610 170 0.102
carboxylic acid metabolic process GO:0019752 338 0.100
negative regulation of cellular metabolic process GO:0031324 407 0.099
negative regulation of cellular component organization GO:0051129 109 0.099
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.096
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.096
aerobic respiration GO:0009060 55 0.091
negative regulation of nucleic acid templated transcription GO:1903507 260 0.089
chromatin modification GO:0016568 200 0.087
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.087
single organism catabolic process GO:0044712 619 0.086
establishment of protein localization GO:0045184 367 0.084
cellular ketone metabolic process GO:0042180 63 0.084
negative regulation of rna biosynthetic process GO:1902679 260 0.079
chromatin organization GO:0006325 242 0.077
positive regulation of cellular biosynthetic process GO:0031328 336 0.076
positive regulation of macromolecule metabolic process GO:0010604 394 0.071
protein transport GO:0015031 345 0.067
regulation of phosphorus metabolic process GO:0051174 230 0.064
cellular amino acid metabolic process GO:0006520 225 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.062
regulation of phosphate metabolic process GO:0019220 230 0.062
positive regulation of rna biosynthetic process GO:1902680 286 0.061
oxoacid metabolic process GO:0043436 351 0.060
negative regulation of gene expression epigenetic GO:0045814 147 0.059
single organism developmental process GO:0044767 258 0.058
fatty acid metabolic process GO:0006631 51 0.058
regulation of gene expression epigenetic GO:0040029 147 0.057
carboxylic acid biosynthetic process GO:0046394 152 0.056
organonitrogen compound catabolic process GO:1901565 404 0.055
regulation of cell cycle GO:0051726 195 0.054
sexual reproduction GO:0019953 216 0.054
positive regulation of biosynthetic process GO:0009891 336 0.053
macromolecule catabolic process GO:0009057 383 0.053
cellular respiration GO:0045333 82 0.053
lipid metabolic process GO:0006629 269 0.051
heterocycle catabolic process GO:0046700 494 0.051
chromatin silencing at telomere GO:0006348 84 0.051
protein localization to nucleus GO:0034504 74 0.050
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.048
er to golgi vesicle mediated transport GO:0006888 86 0.047
positive regulation of cellular protein metabolic process GO:0032270 89 0.046
golgi vesicle transport GO:0048193 188 0.045
organic acid metabolic process GO:0006082 352 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.043
meiotic cell cycle GO:0051321 272 0.042
regulation of signaling GO:0023051 119 0.042
negative regulation of cellular protein metabolic process GO:0032269 85 0.040
regulation of catalytic activity GO:0050790 307 0.039
regulation of biological quality GO:0065008 391 0.039
proteolysis GO:0006508 268 0.038
reproductive process in single celled organism GO:0022413 145 0.038
gene silencing GO:0016458 151 0.038
nuclear division GO:0000280 263 0.037
ion transport GO:0006811 274 0.037
establishment of protein localization to organelle GO:0072594 278 0.037
regulation of signal transduction GO:0009966 114 0.037
sexual sporulation GO:0034293 113 0.036
peptidyl amino acid modification GO:0018193 116 0.036
cellular macromolecule catabolic process GO:0044265 363 0.035
monocarboxylic acid metabolic process GO:0032787 122 0.035
regulation of catabolic process GO:0009894 199 0.035
organic cyclic compound catabolic process GO:1901361 499 0.035
cellular modified amino acid metabolic process GO:0006575 51 0.034
glucan metabolic process GO:0044042 44 0.034
nucleobase containing small molecule metabolic process GO:0055086 491 0.034
single organism reproductive process GO:0044702 159 0.034
negative regulation of rna metabolic process GO:0051253 262 0.033
regulation of molecular function GO:0065009 320 0.033
regulation of carbohydrate biosynthetic process GO:0043255 31 0.032
cellular developmental process GO:0048869 191 0.032
cation transport GO:0006812 166 0.032
cellular lipid metabolic process GO:0044255 229 0.031
posttranscriptional regulation of gene expression GO:0010608 115 0.030
regulation of mitochondrial translation GO:0070129 15 0.030
reproduction of a single celled organism GO:0032505 191 0.029
carboxylic acid catabolic process GO:0046395 71 0.029
regulation of anatomical structure morphogenesis GO:0022603 17 0.029
positive regulation of protein metabolic process GO:0051247 93 0.029
regulation of kinase activity GO:0043549 71 0.029
cell surface receptor signaling pathway GO:0007166 38 0.028
regulation of carbohydrate metabolic process GO:0006109 43 0.028
cellular ion homeostasis GO:0006873 112 0.028
protein complex disassembly GO:0043241 70 0.027
regulation of gluconeogenesis GO:0006111 16 0.027
metallo sulfur cluster assembly GO:0031163 22 0.027
reproductive process GO:0022414 248 0.027
meiotic cell cycle process GO:1903046 229 0.027
small molecule catabolic process GO:0044282 88 0.026
maintenance of location in cell GO:0051651 58 0.026
response to temperature stimulus GO:0009266 74 0.026
cell differentiation GO:0030154 161 0.026
anatomical structure development GO:0048856 160 0.026
regulation of mitochondrion organization GO:0010821 20 0.025
aromatic compound catabolic process GO:0019439 491 0.025
protein targeting GO:0006605 272 0.025
regulation of protein modification process GO:0031399 110 0.025
carbohydrate biosynthetic process GO:0016051 82 0.025
negative regulation of cell cycle process GO:0010948 86 0.025
negative regulation of transcription dna templated GO:0045892 258 0.025
developmental process involved in reproduction GO:0003006 159 0.024
histone modification GO:0016570 119 0.024
nucleoside phosphate metabolic process GO:0006753 458 0.024
regulation of cellular catabolic process GO:0031329 195 0.024
regulation of translation GO:0006417 89 0.024
anatomical structure formation involved in morphogenesis GO:0048646 136 0.024
organophosphate metabolic process GO:0019637 597 0.023
fatty acid biosynthetic process GO:0006633 22 0.023
cellular chemical homeostasis GO:0055082 123 0.023
meiotic nuclear division GO:0007126 163 0.023
regulation of response to stimulus GO:0048583 157 0.023
glycerophospholipid metabolic process GO:0006650 98 0.023
positive regulation of molecular function GO:0044093 185 0.023
carbohydrate derivative metabolic process GO:1901135 549 0.022
cellular amine metabolic process GO:0044106 51 0.022
nuclear transport GO:0051169 165 0.022
monosaccharide biosynthetic process GO:0046364 31 0.022
ion homeostasis GO:0050801 118 0.022
cellular nitrogen compound catabolic process GO:0044270 494 0.022
nucleotide metabolic process GO:0009117 453 0.021
regulation of protein phosphorylation GO:0001932 75 0.021
small molecule biosynthetic process GO:0044283 258 0.021
protein catabolic process GO:0030163 221 0.021
protein import GO:0017038 122 0.021
sporulation GO:0043934 132 0.021
cellular glucan metabolic process GO:0006073 44 0.021
cellular component morphogenesis GO:0032989 97 0.021
regulation of hydrolase activity GO:0051336 133 0.020
glycosyl compound metabolic process GO:1901657 398 0.020
protein phosphorylation GO:0006468 197 0.020
regulation of cell division GO:0051302 113 0.020
protein localization to organelle GO:0033365 337 0.020
cell division GO:0051301 205 0.020
protein modification by small protein conjugation or removal GO:0070647 172 0.020
signal transduction GO:0007165 208 0.020
regulation of phosphorylation GO:0042325 86 0.019
multi organism reproductive process GO:0044703 216 0.019
ribonucleoside triphosphate catabolic process GO:0009203 327 0.019
regulation of protein serine threonine kinase activity GO:0071900 41 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.019
cellular response to chemical stimulus GO:0070887 315 0.019
negative regulation of phosphorus metabolic process GO:0010563 49 0.019
anatomical structure morphogenesis GO:0009653 160 0.019
dna replication GO:0006260 147 0.019
homeostatic process GO:0042592 227 0.019
cation homeostasis GO:0055080 105 0.019
ribonucleoside metabolic process GO:0009119 389 0.019
transition metal ion homeostasis GO:0055076 59 0.018
cellular cation homeostasis GO:0030003 100 0.018
cellular protein catabolic process GO:0044257 213 0.018
macromolecular complex disassembly GO:0032984 80 0.018
ribonucleotide catabolic process GO:0009261 327 0.018
positive regulation of phosphorus metabolic process GO:0010562 147 0.018
positive regulation of translation GO:0045727 34 0.018
nuclear import GO:0051170 57 0.018
regulation of nuclear division GO:0051783 103 0.018
phospholipid biosynthetic process GO:0008654 89 0.018
regulation of developmental process GO:0050793 30 0.017
negative regulation of phosphate metabolic process GO:0045936 49 0.017
monocarboxylic acid biosynthetic process GO:0072330 35 0.017
negative regulation of nuclear division GO:0051784 62 0.017
positive regulation of catalytic activity GO:0043085 178 0.017
organelle inheritance GO:0048308 51 0.017
developmental process GO:0032502 261 0.017
nucleocytoplasmic transport GO:0006913 163 0.017
cell development GO:0048468 107 0.017
protein processing GO:0016485 64 0.017
regulation of glucose metabolic process GO:0010906 27 0.017
regulation of lipid metabolic process GO:0019216 45 0.017
cellular homeostasis GO:0019725 138 0.016
regulation of cellular amine metabolic process GO:0033238 21 0.016
sporulation resulting in formation of a cellular spore GO:0030435 129 0.016
nucleoside triphosphate metabolic process GO:0009141 364 0.016
cellular lipid catabolic process GO:0044242 33 0.016
ethanolamine containing compound metabolic process GO:0042439 21 0.016
coenzyme metabolic process GO:0006732 104 0.016
ubiquitin dependent protein catabolic process GO:0006511 181 0.016
single organism nuclear import GO:1902593 56 0.016
organelle fission GO:0048285 272 0.016
translation GO:0006412 230 0.016
carbohydrate metabolic process GO:0005975 252 0.016
positive regulation of organelle organization GO:0010638 85 0.016
phosphatidylcholine metabolic process GO:0046470 20 0.016
lipid transport GO:0006869 58 0.016
organic acid catabolic process GO:0016054 71 0.015
vesicle mediated transport GO:0016192 335 0.015
cellular protein complex disassembly GO:0043624 42 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
dna templated transcription elongation GO:0006354 91 0.015
negative regulation of meiotic cell cycle GO:0051447 24 0.015
methylation GO:0032259 101 0.015
regulation of vesicle mediated transport GO:0060627 39 0.014
secretion GO:0046903 50 0.014
metal ion transport GO:0030001 75 0.014
cellular response to nutrient GO:0031670 50 0.014
nucleobase containing compound catabolic process GO:0034655 479 0.014
rna catabolic process GO:0006401 118 0.014
dephosphorylation GO:0016311 127 0.014
mrna metabolic process GO:0016071 269 0.014
signaling GO:0023052 208 0.014
dna repair GO:0006281 236 0.014
cellular polysaccharide metabolic process GO:0044264 55 0.014
positive regulation of cellular component organization GO:0051130 116 0.014
intracellular protein transport GO:0006886 319 0.014
regulation of transferase activity GO:0051338 83 0.014
nucleoside triphosphate catabolic process GO:0009143 329 0.014
monosaccharide metabolic process GO:0005996 83 0.014
regulation of dna templated transcription in response to stress GO:0043620 51 0.014
glycosyl compound catabolic process GO:1901658 335 0.013
lipid catabolic process GO:0016042 33 0.013
amine metabolic process GO:0009308 51 0.013
cell aging GO:0007569 70 0.013
organic acid transport GO:0015849 77 0.013
glucose metabolic process GO:0006006 65 0.013
negative regulation of cell division GO:0051782 66 0.013
response to chemical GO:0042221 390 0.013
organic acid biosynthetic process GO:0016053 152 0.013
cellular component disassembly GO:0022411 86 0.013
regulation of proteolysis GO:0030162 44 0.013
nucleoside metabolic process GO:0009116 394 0.013
alcohol biosynthetic process GO:0046165 75 0.013
negative regulation of protein processing GO:0010955 33 0.013
protein localization to membrane GO:0072657 102 0.013
chromatin silencing GO:0006342 147 0.013
negative regulation of catalytic activity GO:0043086 60 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
carbohydrate derivative catabolic process GO:1901136 339 0.013
regulation of protein kinase activity GO:0045859 67 0.013
proton transporting atp synthase complex biogenesis GO:0070272 12 0.012
ribose phosphate metabolic process GO:0019693 384 0.012
regulation of multi organism process GO:0043900 20 0.012
fatty acid catabolic process GO:0009062 17 0.012
positive regulation of apoptotic process GO:0043065 3 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
proton transporting two sector atpase complex assembly GO:0070071 15 0.012
carboxylic acid transport GO:0046942 74 0.012
positive regulation of catabolic process GO:0009896 135 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
localization within membrane GO:0051668 29 0.012
phosphorylation GO:0016310 291 0.012
copper ion transport GO:0006825 16 0.012
organophosphate ester transport GO:0015748 45 0.012
regulation of cell communication GO:0010646 124 0.012
transmembrane transport GO:0055085 349 0.012
regulation of chromosome organization GO:0033044 66 0.011
positive regulation of phosphate metabolic process GO:0045937 147 0.011
multi organism process GO:0051704 233 0.011
mrna catabolic process GO:0006402 93 0.011
organophosphate catabolic process GO:0046434 338 0.011
nucleotide catabolic process GO:0009166 330 0.011
regulation of cell cycle process GO:0010564 150 0.011
cellular metal ion homeostasis GO:0006875 78 0.011
anatomical structure homeostasis GO:0060249 74 0.011
negative regulation of cell cycle GO:0045786 91 0.011
autophagy GO:0006914 106 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
phospholipid metabolic process GO:0006644 125 0.011
regulation of anatomical structure size GO:0090066 50 0.011
nucleoside phosphate catabolic process GO:1901292 331 0.011
positive regulation of mitochondrion organization GO:0010822 16 0.011
purine nucleoside triphosphate catabolic process GO:0009146 329 0.011
sulfur compound metabolic process GO:0006790 95 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.011
purine ribonucleoside metabolic process GO:0046128 380 0.011
proton transporting atp synthase complex assembly GO:0043461 11 0.011
single organism signaling GO:0044700 208 0.011
protein ubiquitination GO:0016567 118 0.011
mitochondrial translation GO:0032543 52 0.011
negative regulation of intracellular signal transduction GO:1902532 27 0.011
modification dependent protein catabolic process GO:0019941 181 0.011
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.010
purine containing compound metabolic process GO:0072521 400 0.010
mitochondrial genome maintenance GO:0000002 40 0.010
purine ribonucleoside catabolic process GO:0046130 330 0.010
mitochondrion localization GO:0051646 29 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.010
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.010
endoplasmic reticulum organization GO:0007029 30 0.010
positive regulation of cell death GO:0010942 3 0.010

COA4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023