Saccharomyces cerevisiae

112 known processes

LEM3 (YNL323W)

Lem3p

(Aliases: BRE3,ROS3)

LEM3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phospholipid transport GO:0015914 23 0.996
establishment or maintenance of cell polarity GO:0007163 96 0.952
intracellular protein transport GO:0006886 319 0.949
Yeast
protein transport GO:0015031 345 0.838
Yeast
phospholipid translocation GO:0045332 12 0.819
lipid transport GO:0006869 58 0.810
regulation of membrane lipid distribution GO:0097035 14 0.793
single organism membrane organization GO:0044802 275 0.657
anion transport GO:0006820 145 0.536
establishment of protein localization GO:0045184 367 0.500
Yeast
vesicle mediated transport GO:0016192 335 0.478
Yeast
endomembrane system organization GO:0010256 74 0.475
ion transport GO:0006811 274 0.463
lipid translocation GO:0034204 13 0.444
fungal type cell wall organization GO:0031505 145 0.412
organic anion transport GO:0015711 114 0.376
cell wall organization or biogenesis GO:0071554 190 0.332
membrane organization GO:0061024 276 0.259
lipid localization GO:0010876 60 0.249
regulation of biological quality GO:0065008 391 0.248
endocytosis GO:0006897 90 0.238
Yeast
organophosphate ester transport GO:0015748 45 0.209
fungal type cell wall organization or biogenesis GO:0071852 169 0.199
developmental process GO:0032502 261 0.176
external encapsulating structure organization GO:0045229 146 0.168
cell wall biogenesis GO:0042546 93 0.168
reproduction of a single celled organism GO:0032505 191 0.162
actin filament based process GO:0030029 104 0.153
cellular protein complex assembly GO:0043623 209 0.125
macromolecule catabolic process GO:0009057 383 0.125
cellular macromolecule catabolic process GO:0044265 363 0.123
negative regulation of macromolecule metabolic process GO:0010605 375 0.122
golgi vesicle transport GO:0048193 188 0.121
establishment of cell polarity GO:0030010 64 0.115
anatomical structure development GO:0048856 160 0.113
single organism developmental process GO:0044767 258 0.112
cytoskeleton organization GO:0007010 230 0.110
cell wall organization GO:0071555 146 0.103
asexual reproduction GO:0019954 48 0.103
vacuole organization GO:0007033 75 0.098
glycoprotein metabolic process GO:0009100 62 0.096
lipid metabolic process GO:0006629 269 0.096
glycosylation GO:0070085 66 0.095
response to endoplasmic reticulum stress GO:0034976 23 0.093
regulation of organelle organization GO:0033043 243 0.091
carbohydrate derivative biosynthetic process GO:1901137 181 0.091
single organism signaling GO:0044700 208 0.089
cell division GO:0051301 205 0.088
actin cytoskeleton organization GO:0030036 100 0.085
regulation of gene expression epigenetic GO:0040029 147 0.083
organelle assembly GO:0070925 118 0.083
single organism carbohydrate metabolic process GO:0044723 237 0.080
carbohydrate metabolic process GO:0005975 252 0.077
cell budding GO:0007114 48 0.076
budding cell bud growth GO:0007117 29 0.076
actin filament organization GO:0007015 56 0.075
anatomical structure morphogenesis GO:0009653 160 0.075
cell growth GO:0016049 89 0.066
mitotic cytokinetic process GO:1902410 45 0.065
proteolysis GO:0006508 268 0.065
growth GO:0040007 157 0.064
reproductive process in single celled organism GO:0022413 145 0.064
cellular component morphogenesis GO:0032989 97 0.063
cytoskeleton dependent cytokinesis GO:0061640 65 0.063
single organism catabolic process GO:0044712 619 0.063
protein catabolic process GO:0030163 221 0.063
filamentous growth of a population of unicellular organisms GO:0044182 109 0.062
carbohydrate derivative metabolic process GO:1901135 549 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.059
ribonucleotide catabolic process GO:0009261 327 0.059
protein glycosylation GO:0006486 57 0.058
dna repair GO:0006281 236 0.058
chromatin silencing GO:0006342 147 0.057
negative regulation of cellular metabolic process GO:0031324 407 0.056
ribonucleoprotein complex subunit organization GO:0071826 152 0.056
budding cell apical bud growth GO:0007118 19 0.055
regulation of cellular component organization GO:0051128 334 0.055
cell differentiation GO:0030154 161 0.055
macromolecule glycosylation GO:0043413 57 0.053
cytokinetic process GO:0032506 78 0.053
organophosphate biosynthetic process GO:0090407 182 0.052
regulation of phosphorus metabolic process GO:0051174 230 0.051
glycerolipid metabolic process GO:0046486 108 0.050
ncrna processing GO:0034470 330 0.050
glycoprotein biosynthetic process GO:0009101 61 0.049
protein localization to organelle GO:0033365 337 0.049
post golgi vesicle mediated transport GO:0006892 72 0.048
purine nucleoside triphosphate metabolic process GO:0009144 356 0.047
phospholipid metabolic process GO:0006644 125 0.046
nucleobase containing compound catabolic process GO:0034655 479 0.046
negative regulation of gene expression epigenetic GO:0045814 147 0.046
single organism cellular localization GO:1902580 375 0.046
ribonucleoside triphosphate catabolic process GO:0009203 327 0.046
cellular glucan metabolic process GO:0006073 44 0.046
protein acylation GO:0043543 66 0.046
nucleotide metabolic process GO:0009117 453 0.046
purine nucleoside triphosphate catabolic process GO:0009146 329 0.045
glycolipid metabolic process GO:0006664 31 0.045
cellular developmental process GO:0048869 191 0.044
protein localization to membrane GO:0072657 102 0.044
modification dependent protein catabolic process GO:0019941 181 0.044
ascospore formation GO:0030437 107 0.042
heterocycle catabolic process GO:0046700 494 0.042
anatomical structure formation involved in morphogenesis GO:0048646 136 0.042
mitotic cytokinesis GO:0000281 58 0.041
nucleobase containing small molecule metabolic process GO:0055086 491 0.041
protein complex biogenesis GO:0070271 314 0.041
protein targeting GO:0006605 272 0.041
organic hydroxy compound metabolic process GO:1901615 125 0.040
sporulation resulting in formation of a cellular spore GO:0030435 129 0.040
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.040
establishment of protein localization to membrane GO:0090150 99 0.039
regulation of protein metabolic process GO:0051246 237 0.038
lipid biosynthetic process GO:0008610 170 0.038
invasive filamentous growth GO:0036267 65 0.038
regulation of cytoskeleton organization GO:0051493 63 0.037
protein complex assembly GO:0006461 302 0.037
cellular response to chemical stimulus GO:0070887 315 0.036
regulation of cellular catabolic process GO:0031329 195 0.036
purine ribonucleotide metabolic process GO:0009150 372 0.036
reproductive process GO:0022414 248 0.036
protein n linked glycosylation GO:0006487 34 0.035
nucleoside phosphate metabolic process GO:0006753 458 0.035
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.035
response to chemical GO:0042221 390 0.035
phospholipid biosynthetic process GO:0008654 89 0.035
establishment of protein localization to organelle GO:0072594 278 0.034
chromatin silencing at silent mating type cassette GO:0030466 53 0.033
sexual sporulation GO:0034293 113 0.033
regulation of gtp catabolic process GO:0033124 84 0.032
signaling GO:0023052 208 0.031
liposaccharide metabolic process GO:1903509 31 0.031
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.031
cellular amino acid metabolic process GO:0006520 225 0.031
alcohol metabolic process GO:0006066 112 0.031
cell communication GO:0007154 345 0.031
organophosphate catabolic process GO:0046434 338 0.030
nucleoside triphosphate metabolic process GO:0009141 364 0.030
purine nucleotide catabolic process GO:0006195 328 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.030
protein modification by small protein conjugation or removal GO:0070647 172 0.029
golgi to plasma membrane transport GO:0006893 33 0.029
purine nucleoside metabolic process GO:0042278 380 0.029
guanosine containing compound metabolic process GO:1901068 111 0.029
endosomal transport GO:0016197 86 0.029
developmental process involved in reproduction GO:0003006 159 0.029
negative regulation of cellular component organization GO:0051129 109 0.029
positive regulation of gtp catabolic process GO:0033126 80 0.029
purine nucleoside catabolic process GO:0006152 330 0.028
filamentous growth GO:0030447 124 0.028
meiotic cell cycle process GO:1903046 229 0.028
purine nucleotide metabolic process GO:0006163 376 0.028
protein lipidation GO:0006497 40 0.028
ubiquitin dependent protein catabolic process GO:0006511 181 0.027
gene silencing GO:0016458 151 0.027
small molecule biosynthetic process GO:0044283 258 0.027
organic acid metabolic process GO:0006082 352 0.027
regulation of dna metabolic process GO:0051052 100 0.027
purine ribonucleoside metabolic process GO:0046128 380 0.027
aromatic compound catabolic process GO:0019439 491 0.027
steroid metabolic process GO:0008202 47 0.027
ribose phosphate metabolic process GO:0019693 384 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.026
mitotic cell cycle GO:0000278 306 0.026
retrograde transport endosome to golgi GO:0042147 33 0.026
pseudohyphal growth GO:0007124 75 0.026
cytokinesis site selection GO:0007105 40 0.025
fungal type cell wall biogenesis GO:0009272 80 0.025
mitochondrion organization GO:0007005 261 0.025
positive regulation of hydrolase activity GO:0051345 112 0.025
polysaccharide metabolic process GO:0005976 60 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.025
posttranscriptional regulation of gene expression GO:0010608 115 0.025
cellular response to abiotic stimulus GO:0071214 62 0.025
aging GO:0007568 71 0.025
regulation of gtpase activity GO:0043087 84 0.024
glycosyl compound metabolic process GO:1901657 398 0.024
nucleotide catabolic process GO:0009166 330 0.024
glycerolipid biosynthetic process GO:0045017 71 0.024
cell wall macromolecule metabolic process GO:0044036 27 0.023
organophosphate metabolic process GO:0019637 597 0.023
nucleoside metabolic process GO:0009116 394 0.023
protein targeting to membrane GO:0006612 52 0.023
protein polymerization GO:0051258 51 0.023
ribonucleoside triphosphate metabolic process GO:0009199 356 0.023
lipoprotein metabolic process GO:0042157 40 0.023
cellular component macromolecule biosynthetic process GO:0070589 24 0.023
positive regulation of gtpase activity GO:0043547 80 0.022
ribonucleoprotein complex assembly GO:0022618 143 0.022
mrna catabolic process GO:0006402 93 0.022
homeostatic process GO:0042592 227 0.022
nucleotide excision repair GO:0006289 50 0.022
negative regulation of gene expression GO:0010629 312 0.022
signal transduction GO:0007165 208 0.021
nucleoside catabolic process GO:0009164 335 0.021
mitotic recombination GO:0006312 55 0.021
actin filament bundle organization GO:0061572 19 0.021
regulation of phosphate metabolic process GO:0019220 230 0.021
regulation of nucleotide catabolic process GO:0030811 106 0.021
purine ribonucleoside catabolic process GO:0046130 330 0.021
chromatin assembly or disassembly GO:0006333 60 0.021
regulation of catabolic process GO:0009894 199 0.020
regulation of hydrolase activity GO:0051336 133 0.020
regulation of protein modification process GO:0031399 110 0.020
response to osmotic stress GO:0006970 83 0.020
organic acid biosynthetic process GO:0016053 152 0.020
peptidyl amino acid modification GO:0018193 116 0.020
mitochondrial genome maintenance GO:0000002 40 0.020
regulation of nucleotide metabolic process GO:0006140 110 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.020
cytokinesis GO:0000910 92 0.020
carbohydrate derivative catabolic process GO:1901136 339 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.019
protein localization to vacuole GO:0072665 92 0.019
negative regulation of organelle organization GO:0010639 103 0.019
positive regulation of molecular function GO:0044093 185 0.019
glucan metabolic process GO:0044042 44 0.019
nucleoside triphosphate catabolic process GO:0009143 329 0.019
cellular protein catabolic process GO:0044257 213 0.019
cellular component assembly involved in morphogenesis GO:0010927 73 0.018
regulation of anatomical structure morphogenesis GO:0022603 17 0.018
carboxylic acid metabolic process GO:0019752 338 0.018
single organism reproductive process GO:0044702 159 0.018
multi organism process GO:0051704 233 0.018
dna recombination GO:0006310 172 0.018
guanosine containing compound catabolic process GO:1901069 109 0.018
ribonucleotide metabolic process GO:0009259 377 0.018
organonitrogen compound biosynthetic process GO:1901566 314 0.018
cell cycle checkpoint GO:0000075 82 0.018
negative regulation of rna biosynthetic process GO:1902679 260 0.018
gtp metabolic process GO:0046039 107 0.018
invasive growth in response to glucose limitation GO:0001403 61 0.018
positive regulation of gene expression GO:0010628 321 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.017
er to golgi vesicle mediated transport GO:0006888 86 0.017
vacuole fusion GO:0097576 40 0.017
regulation of cellular protein metabolic process GO:0032268 232 0.017
ribosome biogenesis GO:0042254 335 0.017
regulation of developmental process GO:0050793 30 0.017
ribonucleoside catabolic process GO:0042454 332 0.017
sterol metabolic process GO:0016125 47 0.017
apoptotic process GO:0006915 30 0.017
regulation of localization GO:0032879 127 0.017
regulation of purine nucleotide catabolic process GO:0033121 106 0.017
translation GO:0006412 230 0.016
positive regulation of nucleoside metabolic process GO:0045979 97 0.016
protein localization to nucleus GO:0034504 74 0.016
secretion GO:0046903 50 0.016
regulation of purine nucleotide metabolic process GO:1900542 109 0.016
response to extracellular stimulus GO:0009991 156 0.016
establishment of protein localization to vacuole GO:0072666 91 0.016
glycerophospholipid biosynthetic process GO:0046474 68 0.016
oxoacid metabolic process GO:0043436 351 0.016
nucleoside phosphate catabolic process GO:1901292 331 0.016
negative regulation of transcription dna templated GO:0045892 258 0.015
microtubule organizing center organization GO:0031023 33 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of cellular component biogenesis GO:0044087 112 0.015
purine ribonucleotide catabolic process GO:0009154 327 0.015
regulation of vesicle mediated transport GO:0060627 39 0.015
microtubule based process GO:0007017 117 0.015
protein acetylation GO:0006473 59 0.015
response to organic cyclic compound GO:0014070 1 0.015
cellular response to oxidative stress GO:0034599 94 0.015
late endosome to vacuole transport GO:0045324 42 0.015
response to unfolded protein GO:0006986 29 0.015
gtp catabolic process GO:0006184 107 0.015
regulation of cellular amine metabolic process GO:0033238 21 0.015
cation transport GO:0006812 166 0.015
organic cyclic compound catabolic process GO:1901361 499 0.015
plasma membrane organization GO:0007009 21 0.015
chromatin organization GO:0006325 242 0.014
cellular nitrogen compound catabolic process GO:0044270 494 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.014
cellular ketone metabolic process GO:0042180 63 0.014
regulation of catalytic activity GO:0050790 307 0.014
carboxylic acid biosynthetic process GO:0046394 152 0.014
response to starvation GO:0042594 96 0.014
replicative cell aging GO:0001302 46 0.014
cellular polysaccharide metabolic process GO:0044264 55 0.014
regulation of carbohydrate metabolic process GO:0006109 43 0.014
chromatin remodeling GO:0006338 80 0.014
beta glucan metabolic process GO:0051273 13 0.014
cellular response to starvation GO:0009267 90 0.014
organonitrogen compound catabolic process GO:1901565 404 0.014
protein localization to endoplasmic reticulum GO:0070972 47 0.014
cellular response to topologically incorrect protein GO:0035967 32 0.014
membrane invagination GO:0010324 43 0.014
cellular carbohydrate catabolic process GO:0044275 33 0.014
nuclear transcribed mrna catabolic process GO:0000956 89 0.014
modification dependent macromolecule catabolic process GO:0043632 203 0.014
sex determination GO:0007530 32 0.013
regulation of dna repair GO:0006282 14 0.013
cellular amino acid biosynthetic process GO:0008652 118 0.013
oxidation reduction process GO:0055114 353 0.013
purine containing compound catabolic process GO:0072523 332 0.013
protein processing GO:0016485 64 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
dephosphorylation GO:0016311 127 0.013
negative regulation of cellular catabolic process GO:0031330 43 0.013
regulation of nucleoside metabolic process GO:0009118 106 0.013
beta glucan biosynthetic process GO:0051274 12 0.013
glucose metabolic process GO:0006006 65 0.013
nucleus organization GO:0006997 62 0.013
gene silencing by rna GO:0031047 3 0.013
regulation of response to dna damage stimulus GO:2001020 17 0.012
positive regulation of cellular catabolic process GO:0031331 128 0.012
sporulation GO:0043934 132 0.012
negative regulation of biosynthetic process GO:0009890 312 0.012
negative regulation of nucleic acid templated transcription GO:1903507 260 0.012
positive regulation of cellular component organization GO:0051130 116 0.012
gpi anchor metabolic process GO:0006505 28 0.012
regulation of actin filament based process GO:0032970 31 0.012
carbohydrate biosynthetic process GO:0016051 82 0.012
cellular carbohydrate metabolic process GO:0044262 135 0.012
regulation of response to stimulus GO:0048583 157 0.012
coenzyme metabolic process GO:0006732 104 0.012
proteasomal protein catabolic process GO:0010498 141 0.012
internal protein amino acid acetylation GO:0006475 52 0.012
positive regulation of nucleotide catabolic process GO:0030813 97 0.012
positive regulation of organelle organization GO:0010638 85 0.012
mitotic cell cycle process GO:1903047 294 0.012
negative regulation of cell cycle GO:0045786 91 0.012
amine metabolic process GO:0009308 51 0.012
regulation of lipid metabolic process GO:0019216 45 0.011
cellular component disassembly GO:0022411 86 0.011
negative regulation of phosphate metabolic process GO:0045936 49 0.011
regulation of protein complex assembly GO:0043254 77 0.011
endoplasmic reticulum organization GO:0007029 30 0.011
chromatin modification GO:0016568 200 0.011
cell development GO:0048468 107 0.011
negative regulation of phosphorus metabolic process GO:0010563 49 0.011
glycolipid biosynthetic process GO:0009247 28 0.011
cellular response to external stimulus GO:0071496 150 0.011
regulation of vacuole organization GO:0044088 20 0.011
regulation of actin cytoskeleton organization GO:0032956 31 0.011
glycosyl compound catabolic process GO:1901658 335 0.011
cell aging GO:0007569 70 0.011
generation of precursor metabolites and energy GO:0006091 147 0.011
protein modification by small protein conjugation GO:0032446 144 0.011
single organism membrane fusion GO:0044801 71 0.011
monocarboxylic acid biosynthetic process GO:0072330 35 0.011
glycerophospholipid metabolic process GO:0006650 98 0.011
protein maturation GO:0051604 76 0.011
sexual reproduction GO:0019953 216 0.011
regulation of polysaccharide metabolic process GO:0032881 15 0.011
positive regulation of nucleotide metabolic process GO:0045981 101 0.011
positive regulation of protein metabolic process GO:0051247 93 0.011
macromolecular complex disassembly GO:0032984 80 0.011
mitotic spindle organization GO:0007052 30 0.011
response to nutrient levels GO:0031667 150 0.011
regulation of protein localization GO:0032880 62 0.011
cell surface receptor signaling pathway GO:0007166 38 0.011
cellular lipid metabolic process GO:0044255 229 0.011
ribonucleoside metabolic process GO:0009119 389 0.010
chromatin silencing at telomere GO:0006348 84 0.010
cellular bud site selection GO:0000282 35 0.010
actin filament bundle assembly GO:0051017 19 0.010
rho protein signal transduction GO:0007266 12 0.010
single organism nuclear import GO:1902593 56 0.010
regulation of ras protein signal transduction GO:0046578 47 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.010
programmed cell death GO:0012501 30 0.010
protein dna complex subunit organization GO:0071824 153 0.010
retrograde vesicle mediated transport golgi to er GO:0006890 28 0.010
double strand break repair GO:0006302 105 0.010
response to topologically incorrect protein GO:0035966 38 0.010
positive regulation of catabolic process GO:0009896 135 0.010

LEM3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010