Saccharomyces cerevisiae

80 known processes

BRO1 (YPL084W)

Bro1p

(Aliases: LPF2,ASI6,NPI3,VPS31)

BRO1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuolar transport GO:0007034 145 0.991
endosomal transport GO:0016197 86 0.941
establishment of protein localization to vacuole GO:0072666 91 0.872
protein localization to vacuole GO:0072665 92 0.865
late endosome to vacuole transport GO:0045324 42 0.846
single organism cellular localization GO:1902580 375 0.730
endocytosis GO:0006897 90 0.593
protein targeting to vacuole GO:0006623 91 0.582
establishment of protein localization to organelle GO:0072594 278 0.506
vesicle organization GO:0016050 68 0.506
protein transport GO:0015031 345 0.503
protein localization to organelle GO:0033365 337 0.449
purine containing compound metabolic process GO:0072521 400 0.447
Mouse
single organism membrane budding GO:1902591 21 0.444
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.404
protein targeting GO:0006605 272 0.365
vesicle mediated transport GO:0016192 335 0.337
mitotic cell cycle process GO:1903047 294 0.333
carbohydrate metabolic process GO:0005975 252 0.309
intralumenal vesicle formation GO:0070676 7 0.300
positive regulation of nucleic acid templated transcription GO:1903508 286 0.300
regulation of endocytosis GO:0030100 17 0.289
localization within membrane GO:0051668 29 0.280
regulation of vesicle mediated transport GO:0060627 39 0.245
Human
response to chemical GO:0042221 390 0.244
cell communication GO:0007154 345 0.239
Fly
membrane budding GO:0006900 22 0.239
regulation of localization GO:0032879 127 0.229
Human
positive regulation of cellular component organization GO:0051130 116 0.226
Human
protein ubiquitination GO:0016567 118 0.219
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.218
nucleotide metabolic process GO:0009117 453 0.214
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.195
cytoskeleton organization GO:0007010 230 0.187
Fly
cell differentiation GO:0030154 161 0.187
Yeast
cellular amino acid metabolic process GO:0006520 225 0.182
multi organism process GO:0051704 233 0.181
Fly
organic hydroxy compound metabolic process GO:1901615 125 0.178
mitotic cell cycle GO:0000278 306 0.177
purine ribonucleoside catabolic process GO:0046130 330 0.176
Mouse
cellular response to extracellular stimulus GO:0031668 150 0.174
nucleoside phosphate metabolic process GO:0006753 458 0.170
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 265 0.168
ribose phosphate metabolic process GO:0019693 384 0.166
Mouse
protein modification by small protein conjugation or removal GO:0070647 172 0.160
heterocycle catabolic process GO:0046700 494 0.160
Mouse
cellular response to starvation GO:0009267 90 0.158
filamentous growth GO:0030447 124 0.158
Yeast
nucleobase containing compound catabolic process GO:0034655 479 0.154
Mouse
establishment of protein localization GO:0045184 367 0.150
positive regulation of transcription dna templated GO:0045893 286 0.150
response to starvation GO:0042594 96 0.149
positive regulation of macromolecule metabolic process GO:0010604 394 0.148
positive regulation of organelle organization GO:0010638 85 0.147
organic cyclic compound catabolic process GO:1901361 499 0.140
Mouse
positive regulation of gene expression GO:0010628 321 0.140
regulation of cellular component biogenesis GO:0044087 112 0.134
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.134
positive regulation of cellular protein metabolic process GO:0032270 89 0.134
chromatin organization GO:0006325 242 0.133
cellular response to external stimulus GO:0071496 150 0.130
mitotic cytokinesis GO:0000281 58 0.128
regulation of transport GO:0051049 85 0.128
Human
regulation of molecular function GO:0065009 320 0.127
Mouse
positive regulation of endocytosis GO:0045807 12 0.127
negative regulation of macromolecule metabolic process GO:0010605 375 0.125
macroautophagy GO:0016236 55 0.121
regulation of intracellular signal transduction GO:1902531 78 0.119
intracellular protein transport GO:0006886 319 0.116
nucleoside metabolic process GO:0009116 394 0.115
Mouse
regulation of cellular component organization GO:0051128 334 0.114
Human
purine nucleoside catabolic process GO:0006152 330 0.113
Mouse
purine ribonucleoside metabolic process GO:0046128 380 0.112
Mouse
ribonucleoside metabolic process GO:0009119 389 0.111
Mouse
cellular carbohydrate metabolic process GO:0044262 135 0.110
purine containing compound catabolic process GO:0072523 332 0.109
Mouse
regulation of cell communication GO:0010646 124 0.105
Fly
proteolysis GO:0006508 268 0.103
response to nutrient levels GO:0031667 150 0.102
protein maturation GO:0051604 76 0.101
Yeast
positive regulation of rna metabolic process GO:0051254 294 0.101
nucleoside triphosphate catabolic process GO:0009143 329 0.101
Mouse
regulation of catalytic activity GO:0050790 307 0.095
Mouse
carbohydrate derivative catabolic process GO:1901136 339 0.095
Mouse
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.094
peroxisome organization GO:0007031 68 0.094
carbohydrate derivative metabolic process GO:1901135 549 0.093
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 356 0.090
Mouse
purine ribonucleotide metabolic process GO:0009150 372 0.090
Mouse
single organism catabolic process GO:0044712 619 0.088
Mouse
nucleobase containing small molecule metabolic process GO:0055086 491 0.088
Mouse
cellular response to dna damage stimulus GO:0006974 287 0.086
signaling GO:0023052 208 0.086
Fly
regulation of protein modification process GO:0031399 110 0.086
purine nucleotide catabolic process GO:0006195 328 0.084
Mouse
single organism membrane organization GO:0044802 275 0.082
positive regulation of cellular biosynthetic process GO:0031328 336 0.082
response to external stimulus GO:0009605 158 0.081
positive regulation of rna biosynthetic process GO:1902680 286 0.081
negative regulation of cellular metabolic process GO:0031324 407 0.080
cellular nitrogen compound catabolic process GO:0044270 494 0.079
Mouse
regulation of protein metabolic process GO:0051246 237 0.079
purine nucleoside triphosphate metabolic process GO:0009144 356 0.077
Mouse
regulation of signal transduction GO:0009966 114 0.077
Fly
modification dependent protein catabolic process GO:0019941 181 0.077
chromatin modification GO:0016568 200 0.076
protein complex biogenesis GO:0070271 314 0.076
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.074
regulation of cellular localization GO:0060341 50 0.072
Human
glycosyl compound catabolic process GO:1901658 335 0.072
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 262 0.072
cytokinesis GO:0000910 92 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.069
response to organic substance GO:0010033 182 0.067
glycosyl compound metabolic process GO:1901657 398 0.066
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 327 0.066
Mouse
organonitrogen compound biosynthetic process GO:1901566 314 0.065
protein catabolic process GO:0030163 221 0.064
ribonucleotide catabolic process GO:0009261 327 0.062
Mouse
cellular macromolecule catabolic process GO:0044265 363 0.062
purine ribonucleotide catabolic process GO:0009154 327 0.061
Mouse
lipid modification GO:0030258 37 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.061
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.058
nucleotide catabolic process GO:0009166 330 0.057
Mouse
cellular response to chemical stimulus GO:0070887 315 0.057
ribonucleotide metabolic process GO:0009259 377 0.055
Mouse
transmembrane transport GO:0055085 349 0.055
regulation of phosphorus metabolic process GO:0051174 230 0.054
positive regulation of cellular catabolic process GO:0031331 128 0.054
regulation of cellular catabolic process GO:0031329 195 0.051
ribonucleoside catabolic process GO:0042454 332 0.051
Mouse
organelle localization GO:0051640 128 0.051
cellular response to organic substance GO:0071310 159 0.051
regulation of dna replication GO:0006275 51 0.051
nucleoside triphosphate metabolic process GO:0009141 364 0.051
Mouse
regulation of dna templated transcription elongation GO:0032784 44 0.050
actin filament based process GO:0030029 104 0.050
regulation of phosphate metabolic process GO:0019220 230 0.050
endosome organization GO:0007032 9 0.049
single organism developmental process GO:0044767 258 0.048
Human Yeast
cellular metal ion homeostasis GO:0006875 78 0.048
organophosphate catabolic process GO:0046434 338 0.048
Mouse
g1 s transition of mitotic cell cycle GO:0000082 64 0.048
positive regulation of secretion by cell GO:1903532 2 0.047
regulation of response to stimulus GO:0048583 157 0.047
Fly
autophagy GO:0006914 106 0.047
aromatic compound catabolic process GO:0019439 491 0.046
Mouse
cellular amino acid biosynthetic process GO:0008652 118 0.046
purine nucleoside metabolic process GO:0042278 380 0.046
Mouse
developmental process GO:0032502 261 0.046
Human Yeast
regulation of biological quality GO:0065008 391 0.046
nucleophagy GO:0044804 34 0.046
regulation of protein complex assembly GO:0043254 77 0.045
positive regulation of catalytic activity GO:0043085 178 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.044
Mouse
signal transduction GO:0007165 208 0.043
Fly
purine nucleoside triphosphate catabolic process GO:0009146 329 0.043
Mouse
regulation of cellular protein metabolic process GO:0032268 232 0.042
response to extracellular stimulus GO:0009991 156 0.040
protein processing GO:0016485 64 0.040
Yeast
maintenance of location in cell GO:0051651 58 0.040
positive regulation of protein metabolic process GO:0051247 93 0.039
macromolecule catabolic process GO:0009057 383 0.039
protein modification by small protein conjugation GO:0032446 144 0.038
lipid metabolic process GO:0006629 269 0.038
histone modification GO:0016570 119 0.038
anatomical structure formation involved in morphogenesis GO:0048646 136 0.038
Yeast
protein deubiquitination GO:0016579 17 0.037
positive regulation of molecular function GO:0044093 185 0.037
response to abiotic stimulus GO:0009628 159 0.037
Yeast
intracellular signal transduction GO:0035556 112 0.036
cellular response to oxygen containing compound GO:1901701 43 0.035
negative regulation of dna metabolic process GO:0051053 36 0.034
covalent chromatin modification GO:0016569 119 0.034
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 33 0.033
organonitrogen compound catabolic process GO:1901565 404 0.033
Mouse
regulation of dna repair GO:0006282 14 0.033
autophagic vacuole assembly GO:0000045 16 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.033
cation homeostasis GO:0055080 105 0.033
cellular homeostasis GO:0019725 138 0.033
cellular cation homeostasis GO:0030003 100 0.032
positive regulation of cellular component biogenesis GO:0044089 45 0.032
actin cytoskeleton organization GO:0030036 100 0.032
anatomical structure morphogenesis GO:0009653 160 0.032
Human Yeast
response to acid chemical GO:0001101 19 0.032
sporulation resulting in formation of a cellular spore GO:0030435 129 0.031
Yeast
cellular response to abiotic stimulus GO:0071214 62 0.031
regulation of catabolic process GO:0009894 199 0.031
peroxisome degradation GO:0030242 22 0.030
cellular ketone metabolic process GO:0042180 63 0.030
carbohydrate derivative biosynthetic process GO:1901137 181 0.030
positive regulation of exocytosis GO:0045921 2 0.030
chemical homeostasis GO:0048878 137 0.030
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.030
regulation of dna metabolic process GO:0051052 100 0.030
cellular response to nutrient levels GO:0031669 144 0.030
homeostatic process GO:0042592 227 0.029
positive regulation of secretion GO:0051047 2 0.029
regulation of receptor mediated endocytosis GO:0048259 4 0.029
dna repair GO:0006281 236 0.029
cell cycle phase transition GO:0044770 144 0.029
organelle assembly GO:0070925 118 0.029
Fly
single organism signaling GO:0044700 208 0.028
Fly
regulation of fatty acid oxidation GO:0046320 3 0.028
mrna metabolic process GO:0016071 269 0.028
response to oxygen containing compound GO:1901700 61 0.028
positive regulation of biosynthetic process GO:0009891 336 0.028
dna templated transcription elongation GO:0006354 91 0.028
cellular developmental process GO:0048869 191 0.027
Human Yeast
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.027
sulfur compound metabolic process GO:0006790 95 0.027
atp catabolic process GO:0006200 224 0.026
secretion by cell GO:0032940 50 0.026
positive regulation of transport GO:0051050 32 0.026
Human
nucleoside phosphate catabolic process GO:1901292 331 0.026
Mouse
microtubule cytoskeleton organization GO:0000226 109 0.026
Fly
cell cycle g2 m phase transition GO:0044839 39 0.026
cellular protein catabolic process GO:0044257 213 0.026
purine nucleotide metabolic process GO:0006163 376 0.025
Mouse
cellular chemical homeostasis GO:0055082 123 0.025
positive regulation of signal transduction GO:0009967 20 0.025
Fly
negative regulation of cellular biosynthetic process GO:0031327 312 0.025
positive regulation of nucleotide catabolic process GO:0030813 97 0.025
cellular response to oxidative stress GO:0034599 94 0.025
anatomical structure development GO:0048856 160 0.025
Human Yeast
positive regulation of dna templated transcription elongation GO:0032786 42 0.025
regulation of signaling GO:0023051 119 0.024
Fly
cellular protein complex assembly GO:0043623 209 0.024
pseudohyphal growth GO:0007124 75 0.023
response to oxidative stress GO:0006979 99 0.023
cell division GO:0051301 205 0.023
organic acid biosynthetic process GO:0016053 152 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.023
membrane organization GO:0061024 276 0.023
nucleoside catabolic process GO:0009164 335 0.022
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.022
filamentous growth of a population of unicellular organisms GO:0044182 109 0.022
Yeast
membrane invagination GO:0010324 43 0.022
positive regulation of fatty acid oxidation GO:0046321 3 0.022
single organism membrane invagination GO:1902534 43 0.022
negative regulation of multi organism process GO:0043901 6 0.022
positive regulation of catabolic process GO:0009896 135 0.022
chromatin remodeling GO:0006338 80 0.022
response to uv GO:0009411 4 0.022
organophosphate metabolic process GO:0019637 597 0.022
Mouse
atp metabolic process GO:0046034 251 0.021
negative regulation of transcription dna templated GO:0045892 258 0.021
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 12 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.021
posttranscriptional regulation of gene expression GO:0010608 115 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.021
Mouse
ubiquitin dependent protein catabolic process GO:0006511 181 0.020
regulation of protein ubiquitination GO:0031396 20 0.020
ribosomal small subunit biogenesis GO:0042274 124 0.020
negative regulation of growth GO:0045926 13 0.020
response to inorganic substance GO:0010035 47 0.020
protein deacetylation GO:0006476 26 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.019
invasive growth in response to glucose limitation GO:0001403 61 0.019
Yeast
ion transport GO:0006811 274 0.019
negative regulation of protein modification process GO:0031400 37 0.019
maintenance of location GO:0051235 66 0.019
mitotic cell cycle phase transition GO:0044772 141 0.018
dna replication GO:0006260 147 0.018
nucleoside monophosphate metabolic process GO:0009123 267 0.018
pigment biosynthetic process GO:0046148 22 0.018
positive regulation of nucleoside metabolic process GO:0045979 97 0.018
programmed cell death GO:0012501 30 0.018
nitrogen compound transport GO:0071705 212 0.017
negative regulation of rna metabolic process GO:0051253 262 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.017
regulation of purine nucleotide metabolic process GO:1900542 109 0.017
dna dependent dna replication GO:0006261 115 0.017
regulation of cellular response to drug GO:2001038 3 0.017
positive regulation of cell communication GO:0010647 28 0.017
Fly
sexual reproduction GO:0019953 216 0.017
small molecule catabolic process GO:0044282 88 0.016
metal ion homeostasis GO:0055065 79 0.016
cytoskeleton dependent cytokinesis GO:0061640 65 0.016
regulation of organelle organization GO:0033043 243 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
positive regulation of phosphorus metabolic process GO:0010562 147 0.016
single organism carbohydrate metabolic process GO:0044723 237 0.016
g2 m transition of mitotic cell cycle GO:0000086 38 0.016
regulation of multi organism process GO:0043900 20 0.016
multi organism reproductive process GO:0044703 216 0.016
mrna processing GO:0006397 185 0.015
regulation of hydrolase activity GO:0051336 133 0.015
reproduction of a single celled organism GO:0032505 191 0.015
protein complex assembly GO:0006461 302 0.015
Fly
endomembrane system organization GO:0010256 74 0.015
negative regulation of signal transduction GO:0009968 30 0.014
negative regulation of biosynthetic process GO:0009890 312 0.014
carboxylic acid biosynthetic process GO:0046394 152 0.014
regulation of sodium ion transport GO:0002028 1 0.014
early endosome to late endosome transport GO:0045022 1 0.014
Human
response to temperature stimulus GO:0009266 74 0.014
regulation of cellular ketone metabolic process GO:0010565 42 0.014
nucleoside monophosphate catabolic process GO:0009125 224 0.014
macromolecular complex disassembly GO:0032984 80 0.014
response to hydrogen peroxide GO:0042542 12 0.014
apoptotic process GO:0006915 30 0.014
cell cycle g1 s phase transition GO:0044843 64 0.014
positive regulation of cell cycle GO:0045787 32 0.014
protein phosphorylation GO:0006468 197 0.014
alcohol metabolic process GO:0006066 112 0.013
regulation of translation GO:0006417 89 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.013
positive regulation of translation GO:0045727 34 0.013
piecemeal microautophagy of nucleus GO:0034727 33 0.013
protein localization to golgi apparatus GO:0034067 13 0.012
peptidyl amino acid modification GO:0018193 116 0.012
positive regulation of signaling GO:0023056 20 0.012
Fly
regulation of protein catabolic process GO:0042176 40 0.012
growth GO:0040007 157 0.012
Yeast Fly
organic acid metabolic process GO:0006082 352 0.012
translation GO:0006412 230 0.012
cell surface receptor signaling pathway GO:0007166 38 0.012
Fly
positive regulation of hydrolase activity GO:0051345 112 0.012
response to endogenous stimulus GO:0009719 26 0.011
cell wall macromolecule metabolic process GO:0044036 27 0.011
carboxylic acid metabolic process GO:0019752 338 0.011
cellular ion homeostasis GO:0006873 112 0.011
double strand break repair GO:0006302 105 0.011
cell wall polysaccharide metabolic process GO:0010383 17 0.011
ascospore formation GO:0030437 107 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
regulation of lipid metabolic process GO:0019216 45 0.011
cellular component morphogenesis GO:0032989 97 0.011
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
macromolecule deacylation GO:0098732 27 0.011
golgi to vacuole transport GO:0006896 23 0.011
modification dependent macromolecule catabolic process GO:0043632 203 0.011
vacuole organization GO:0007033 75 0.011
reproductive process GO:0022414 248 0.011
carboxylic acid catabolic process GO:0046395 71 0.011
cvt pathway GO:0032258 37 0.011
negative regulation of gene expression GO:0010629 312 0.011
secretion GO:0046903 50 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
cellular carbohydrate biosynthetic process GO:0034637 49 0.011
response to organic cyclic compound GO:0014070 1 0.010
regulation of cell cycle GO:0051726 195 0.010
positive regulation of apoptotic process GO:0043065 3 0.010
positive regulation of sodium ion transport by positive regulation of transcription from rna polymerase ii promoter GO:0061423 1 0.010
positive regulation of protein modification process GO:0031401 49 0.010

BRO1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
disease of metabolism DOID:0014667 0 0.010