IMP

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Homo sapiens

3 genes annotated in human

complement receptor mediated signaling pathway

A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "complement receptor mediated signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "complement receptor mediated signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.822
ALOX5	arachidonate 5-lipoxygenase	0.795
AQP9	aquaporin 9	0.648
S100A12	S100 calcium binding protein A12	0.611
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.505
CD163	CD163 molecule	0.497
TREM1	triggering receptor expressed on myeloid cells 1	0.488
FPR2	formyl peptide receptor 2	0.428	Human
CLEC5A	C-type lectin domain family 5, member A	0.401
SIGLEC7	sialic acid binding Ig-like lectin 7	0.395
VSIG4	V-set and immunoglobulin domain containing 4	0.372
ADORA3	adenosine A3 receptor	0.309
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.240
FPR1	formyl peptide receptor 1	0.237	Human
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.217
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.200
CD14	CD14 molecule	0.197
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.187
CLEC4E	C-type lectin domain family 4, member E	0.181
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.179
MSR1	macrophage scavenger receptor 1	0.158
MARCO	macrophage receptor with collagenous structure	0.154
CCR1	chemokine (C-C motif) receptor 1	0.130
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.107
IL10	interleukin 10	0.100
FPR3	formyl peptide receptor 3	0.099	Human
SLAMF8	SLAM family member 8	0.098
CLEC7A	C-type lectin domain family 7, member A	0.097
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.092
HK3	hexokinase 3 (white cell)	0.087
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.087
FCAR	Fc fragment of IgA, receptor for	0.084
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.069
CD86	CD86 molecule	0.069
GPR84	G protein-coupled receptor 84	0.065
SIGLEC9	sialic acid binding Ig-like lectin 9	0.063
IGSF6	immunoglobulin superfamily, member 6	0.063
NLRP3	NLR family, pyrin domain containing 3	0.059
IL18RAP	interleukin 18 receptor accessory protein	0.057
FFAR2	free fatty acid receptor 2	0.056
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.052
CMKLR1	chemokine-like receptor 1	0.051	Human
CD300A	CD300a molecule	0.051
C3AR1	complement component 3a receptor 1	0.050	Human Rat
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.050
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.050
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.050
CLEC4A	C-type lectin domain family 4, member A	0.048
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.046
HCK	hemopoietic cell kinase	0.044
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.043
C5AR1	complement component 5a receptor 1	0.042
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.040
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.040
C1QB	complement component 1, q subcomponent, B chain	0.039
EMR2	egf-like module containing, mucin-like, hormone receptor-like 2	0.039
CD300C	CD300c molecule	0.037
CXCR2	chemokine (C-X-C motif) receptor 2	0.036
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.036
CD84	CD84 molecule	0.035
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.035
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.035
KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	0.034
CYBB	cytochrome b-245, beta polypeptide	0.034
S100A9	S100 calcium binding protein A9	0.033
ACP5	acid phosphatase 5, tartrate resistant	0.033
CD300LF	CD300 molecule-like family member f	0.030
ADAMDEC1	ADAM-like, decysin 1	0.028
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.028
TLR6	toll-like receptor 6	0.027
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.027
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.025
PTAFR	platelet-activating factor receptor	0.025
TLR1	toll-like receptor 1	0.025
CAMP	cathelicidin antimicrobial peptide	0.025
TLR8	toll-like receptor 8	0.025
CFP	complement factor properdin	0.024
NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	0.024
CCL7	chemokine (C-C motif) ligand 7	0.023
C19orf59	chromosome 19 open reading frame 59	0.022
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.022
IL1R2	interleukin 1 receptor, type II	0.022
C1QC	complement component 1, q subcomponent, C chain	0.021
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.021
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.021
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.021
IL1RN	interleukin 1 receptor antagonist	0.021
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.021
CD80	CD80 molecule	0.021
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.021
CCL8	chemokine (C-C motif) ligand 8	0.021
APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	0.020
C1QA	complement component 1, q subcomponent, A chain	0.020
GIMAP5	GTPase, IMAP family member 5	0.020
F13A1	coagulation factor XIII, A1 polypeptide	0.020
CCR5	chemokine (C-C motif) receptor 5	0.019
MPEG1	macrophage expressed 1	0.019
HAVCR2	hepatitis A virus cellular receptor 2	0.019
SIRPB1	signal-regulatory protein beta 1	0.018
IL1B	interleukin 1, beta	0.018
BEST1	bestrophin 1	0.018
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.018
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.018
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.018
CD68	CD68 molecule	0.018
HP	haptoglobin	0.018
PLEK	pleckstrin	0.017
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.017
MGAM	maltase-glucoamylase (alpha-glucosidase)	0.015
STEAP4	STEAP family member 4	0.015
AMICA1	adhesion molecule, interacts with CXADR antigen 1	0.015
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.015
CCL23	chemokine (C-C motif) ligand 23	0.015
SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.014
CLEC4D	C-type lectin domain family 4, member D	0.014
TM6SF1	transmembrane 6 superfamily member 1	0.014
BST1	bone marrow stromal cell antigen 1	0.014
ADPRH	ADP-ribosylarginine hydrolase	0.014
ADAP2	ArfGAP with dual PH domains 2	0.014
LRRC25	leucine rich repeat containing 25	0.014
MS4A14	membrane-spanning 4-domains, subfamily A, member 14	0.014
GTF2H3	general transcription factor IIH, polypeptide 3, 34kDa	0.014
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.014
SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	0.013
FOLR3	folate receptor 3 (gamma)	0.013
SELL	selectin L	0.013
AOAH	acyloxyacyl hydrolase (neutrophil)	0.013
CXCL13	chemokine (C-X-C motif) ligand 13	0.013
VNN1	vanin 1	0.013
CYTH4	cytohesin 4	0.012
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.012
C17orf60	chromosome 17 open reading frame 60	0.012
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.012
C2	complement component 2	0.012
DPEP2	dipeptidase 2	0.012
CXorf21	chromosome X open reading frame 21	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012
SLC16A6	solute carrier family 16, member 6 (monocarboxylic acid transporter 7)	0.011
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.011
CDA	cytidine deaminase	0.011
HAL	histidine ammonia-lyase	0.011
RNASE3	ribonuclease, RNase A family, 3	0.011
EMILIN2	elastin microfibril interfacer 2	0.011
GPR34	G protein-coupled receptor 34	0.011
CLC	Charcot-Leyden crystal protein	0.011
TREM2	triggering receptor expressed on myeloid cells 2	0.010
LYZ	lysozyme	0.010
PHACTR1	phosphatase and actin regulator 1	0.010
VNN2	vanin 2	0.010
IFNG	interferon, gamma	0.010
DHRS9	dehydrogenase/reductase (SDR family) member 9	0.010
PRDM1	PR domain containing 1, with ZNF domain	0.010