IMP

Process View

Homo sapiens

2 genes annotated in human

regulation of high density lipoprotein particle clearance

Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of high density lipoprotein particle clearance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of high density lipoprotein particle clearance" (in gray)

Name	Description	Probability	Func Analog Organism
APOA1	apolipoprotein A-I	1.000
RPL18A	ribosomal protein L18a	1.000
ALB	albumin	0.998
MDK	midkine (neurite growth-promoting factor 2)	0.725
FGA	fibrinogen alpha chain	0.492
APOB	apolipoprotein B (including Ag(x) antigen)	0.348
APOA2	apolipoprotein A-II	0.333
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.287
RIBC2	RIB43A domain with coiled-coils 2	0.243
HP	haptoglobin	0.183
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.113
PLA2G1B	phospholipase A2, group IB (pancreas)	0.101
HPD	4-hydroxyphenylpyruvate dioxygenase	0.092
AHSG	alpha-2-HS-glycoprotein	0.088
CA5A	carbonic anhydrase VA, mitochondrial	0.082
PAH	phenylalanine hydroxylase	0.073
KIAA1377	KIAA1377	0.071
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.065
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.064
FABP1	fatty acid binding protein 1, liver	0.060
APOA4	apolipoprotein A-IV	0.057
APOC1	apolipoprotein C-I	0.056
OTC	ornithine carbamoyltransferase	0.055
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.051
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.051
PON1	paraoxonase 1	0.051
CPB2	carboxypeptidase B2 (plasma)	0.050
LCAT	lecithin-cholesterol acyltransferase	0.049
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.049
G6PC	glucose-6-phosphatase, catalytic subunit	0.049
C4BPB	complement component 4 binding protein, beta	0.046
MAT1A	methionine adenosyltransferase I, alpha	0.045
KNG1	kininogen 1	0.045
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.040
LECT2	leukocyte cell-derived chemotaxin 2	0.039
FGG	fibrinogen gamma chain	0.039
PLG	plasminogen	0.039
ALDOB	aldolase B, fructose-bisphosphate	0.036
AMBP	alpha-1-microglobulin/bikunin precursor	0.035
APOC2	apolipoprotein C-II	0.034
CRP	C-reactive protein, pentraxin-related	0.034
C4BPA	complement component 4 binding protein, alpha	0.033
F11	coagulation factor XI	0.033
ORM2	orosomucoid 2	0.032
APOC4	apolipoprotein C-IV	0.032
MBL2	mannose-binding lectin (protein C) 2, soluble	0.031
HPX	hemopexin	0.030
HAL	histidine ammonia-lyase	0.030
MASP2	mannan-binding lectin serine peptidase 2	0.030
BHMT	betaine--homocysteine S-methyltransferase	0.030
RPL36	ribosomal protein L36	0.030
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.029
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.028
REG1A	regenerating islet-derived 1 alpha	0.028
PKLR	pyruvate kinase, liver and RBC	0.027
ORM1	orosomucoid 1	0.027
ADH6	alcohol dehydrogenase 6 (class V)	0.026
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.024
TREH	trehalase (brush-border membrane glycoprotein)	0.024
SLC38A3	solute carrier family 38, member 3	0.023
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.023
APCS	amyloid P component, serum	0.022
DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	0.022
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.022
SAA4	serum amyloid A4, constitutive	0.022
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.022
GYS2	glycogen synthase 2 (liver)	0.022
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.021
DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.021
ZG16	zymogen granule protein 16 homolog (rat)	0.021
HABP2	hyaluronan binding protein 2	0.020
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.020
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.020
AFM	afamin	0.019
GLYAT	glycine-N-acyltransferase	0.018
AES	amino-terminal enhancer of split	0.018
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.018
ELANE	elastase, neutrophil expressed	0.018
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.017
FGL1	fibrinogen-like 1	0.017
TF	transferrin	0.017
LBP	lipopolysaccharide binding protein	0.017
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.016
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.016
PNLIP	pancreatic lipase	0.016	Human
ITIH2	inter-alpha (globulin) inhibitor H2	0.016
CTRC	chymotrypsin C (caldecrin)	0.016
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.016
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.015
CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	0.015
PNLIPRP1	pancreatic lipase-related protein 1	0.015	Human
C9	complement component 9	0.015
F2	coagulation factor II (thrombin)	0.015
TDO2	tryptophan 2,3-dioxygenase	0.014
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.014
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.014
DPYS	dihydropyrimidinase	0.014
ADHFE1	alcohol dehydrogenase, iron containing, 1	0.014
FGB	fibrinogen beta chain	0.014
AFP	alpha-fetoprotein	0.013
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.013
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.013
GCKR	glucokinase (hexokinase 4) regulator	0.013
ARG1	arginase, liver	0.013
RPS14	ribosomal protein S14	0.013
RPL8	ribosomal protein L8	0.013
ANGPTL3	angiopoietin-like 3	0.013
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.013
RDH16	retinol dehydrogenase 16 (all-trans)	0.013
HRG	histidine-rich glycoprotein	0.012
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.012
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.012
ITIH3	inter-alpha (globulin) inhibitor H3	0.012
CA3	carbonic anhydrase III, muscle specific	0.012
C8G	complement component 8, gamma polypeptide	0.012
REG3A	regenerating islet-derived 3 alpha	0.012
INHBA	inhibin, beta A	0.012
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.012
TMSB4Y	thymosin beta 4, Y-linked	0.012
GC	group-specific component (vitamin D binding protein)	0.012
VHL	von Hippel-Lindau tumor suppressor	0.012
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.011
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.011
F9	coagulation factor IX	0.011
PRSS2	protease, serine, 2 (trypsin 2)	0.011
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.011
KRT16	keratin 16	0.011
LPA	lipoprotein, Lp(a)	0.011
PRLR	prolactin receptor	0.011
F13B	coagulation factor XIII, B polypeptide	0.011
FABP2	fatty acid binding protein 2, intestinal	0.011
CRHBP	corticotropin releasing hormone binding protein	0.011
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.011
MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.011
AADAC	arylacetamide deacetylase (esterase)	0.010
APOF	apolipoprotein F	0.010
ALAS2	aminolevulinate, delta-, synthase 2	0.010
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.010
TTR	transthyretin	0.010
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B	0.010
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.010