IMP

Process View

Homo sapiens

19 genes annotated in human

er to golgi vesicle mediated transport

The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "er to golgi vesicle mediated transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "er to golgi vesicle mediated transport" (in gray)

Name	Description	Probability	Func Analog Organism
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.971	Yeast
COPA	coatomer protein complex, subunit alpha	0.963	Yeast
TMED2	transmembrane emp24 domain trafficking protein 2	0.942	Yeast Worm
COPB1	coatomer protein complex, subunit beta 1	0.932	Yeast
SEC23A	Sec23 homolog A (S. cerevisiae)	0.854	Yeast
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	0.787	Yeast
ARCN1	archain 1	0.678	Yeast
COPG	coatomer protein complex, subunit gamma	0.408	Yeast
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.375
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.335
COPE	coatomer protein complex, subunit epsilon	0.269
USO1	USO1 vesicle docking protein homolog (yeast)	0.263
SEC13	SEC13 homolog (S. cerevisiae)	0.233	Yeast Rat
KLHL3	kelch-like 3 (Drosophila)	0.233	Human
SEC24D	SEC24 family, member D (S. cerevisiae)	0.229	Yeast
SEC24A	SEC24 family, member A (S. cerevisiae)	0.214
SURF4	surfeit 4	0.197	Yeast
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.173
LMAN1	lectin, mannose-binding, 1	0.166
TMED9	transmembrane emp24 protein transport domain containing 9	0.156	Yeast Fly
IDI1	isopentenyl-diphosphate delta isomerase 1	0.143
TSC22D4	TSC22 domain family, member 4	0.138
ERN1	endoplasmic reticulum to nucleus signaling 1	0.128
SEC31A	SEC31 homolog A (S. cerevisiae)	0.107	Yeast
SCFD1	sec1 family domain containing 1	0.100	Yeast
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.092
WNK4	WNK lysine deficient protein kinase 4	0.091	Human
KLHL2	kelch-like 2, Mayven (Drosophila)	0.087	Human
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.073
SYNRG	synergin, gamma	0.072
ERGIC3	ERGIC and golgi 3	0.072
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.069
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.068
COPZ1	coatomer protein complex, subunit zeta 1	0.062
OXSR1	oxidative-stress responsive 1	0.056
SEC23B	Sec23 homolog B (S. cerevisiae)	0.056	Yeast
CUL3	cullin 3	0.055
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.050
KLHL12	kelch-like 12 (Drosophila)	0.048
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.046
PRMT6	protein arginine methyltransferase 6	0.040
CSNK1A1	casein kinase 1, alpha 1	0.040	Yeast
EHD1	EH-domain containing 1	0.040
COG4	component of oligomeric golgi complex 4	0.040
COG5	component of oligomeric golgi complex 5	0.038
TMED7	transmembrane emp24 protein transport domain containing 7	0.038	Yeast
SORT1	sortilin 1	0.037	Human
TRAPPC3	trafficking protein particle complex 3	0.036
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	0.035
GOLGA5	golgin A5	0.034
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.032
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.032
MCFD2	multiple coagulation factor deficiency 2	0.031
SPTB	spectrin, beta, erythrocytic	0.029
SEC24C	SEC24 family, member C (S. cerevisiae)	0.028	Yeast
COG6	component of oligomeric golgi complex 6	0.027
NSF	N-ethylmaleimide-sensitive factor	0.027
C19orf10	chromosome 19 open reading frame 10	0.026
SPOP	speckle-type POZ protein	0.026
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.026
C20orf24	chromosome 20 open reading frame 24	0.024
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.024
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.024
COPG2	coatomer protein complex, subunit gamma 2	0.023
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.023
TRAM1	translocation associated membrane protein 1	0.021
DAPK1	death-associated protein kinase 1	0.021
SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	0.021
ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	0.020
CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	0.020
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.020
YIPF5	Yip1 domain family, member 5	0.019
SELS	selenoprotein S	0.019
YKT6	YKT6 v-SNARE homolog (S. cerevisiae)	0.019
TBCB	tubulin folding cofactor B	0.019
SMAD3	SMAD family member 3	0.018
BTBD10	BTB (POZ) domain containing 10	0.018
SC4MOL	sterol-C4-methyl oxidase-like	0.018
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.018
GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1	0.017
CSNK2B	casein kinase 2, beta polypeptide	0.017
SRP54	signal recognition particle 54kDa	0.017
MED28	mediator complex subunit 28	0.017
TTN	titin	0.017
AMFR	autocrine motility factor receptor	0.016
NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	0.016
FAM18B1	family with sequence similarity 18, member B1	0.016
NUDCD1	NudC domain containing 1	0.016
PGM3	phosphoglucomutase 3	0.015
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.015
GOLGA2	golgin A2	0.015
RUSC2	RUN and SH3 domain containing 2	0.015
C12orf44	chromosome 12 open reading frame 44	0.015
CLTB	clathrin, light chain B	0.015
RFWD2	ring finger and WD repeat domain 2	0.014
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.014
SREBF2	sterol regulatory element binding transcription factor 2	0.014
GORAB	golgin, RAB6-interacting	0.014
SEC24B	SEC24 family, member B (S. cerevisiae)	0.014	Yeast Mouse
SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	0.014
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.014
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.014
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.014
CHMP1A	chromatin modifying protein 1A	0.014
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	0.014
MLF2	myeloid leukemia factor 2	0.014
HMGN4	high mobility group nucleosomal binding domain 4	0.013
BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like	0.013	Yeast
FYCO1	FYVE and coiled-coil domain containing 1	0.013
SERP1	stress-associated endoplasmic reticulum protein 1	0.013
NSFL1C	NSFL1 (p97) cofactor (p47)	0.013
OCRL	oculocerebrorenal syndrome of Lowe	0.013
MAP1B	microtubule-associated protein 1B	0.012
RAB1A	RAB1A, member RAS oncogene family	0.012
TPD52L2	tumor protein D52-like 2	0.012
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.012
EIF4E2	eukaryotic translation initiation factor 4E family member 2	0.012
FAM50A	family with sequence similarity 50, member A	0.012
TFIP11	tuftelin interacting protein 11	0.012
PGRMC1	progesterone receptor membrane component 1	0.012
DERL1	Der1-like domain family, member 1	0.012
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.012
MAP7D1	MAP7 domain containing 1	0.012
CSNK1D	casein kinase 1, delta	0.012	Yeast
C12orf23	chromosome 12 open reading frame 23	0.011
RAB24	RAB24, member RAS oncogene family	0.011
ADAM9	ADAM metallopeptidase domain 9	0.011
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.011
SAR1B	SAR1 homolog B (S. cerevisiae)	0.011
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.011
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.011
ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	0.011
LRRK2	leucine-rich repeat kinase 2	0.011
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.011
SUPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	0.010
GOLGA4	golgin A4	0.010
CALU	calumenin	0.010