IMP

Process View

Homo sapiens

1 genes annotated in human

hard palate development

The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hard palate development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hard palate development" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD1	SMAD family member 1	1.000
POU5F1	POU class 5 homeobox 1	1.000
ADAM17	ADAM metallopeptidase domain 17	0.989
SMAD7	SMAD family member 7	0.867
SMAD3	SMAD family member 3	0.832
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.811
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.796
SMAD4	SMAD family member 4	0.656
AR	androgen receptor	0.610
PBK	PDZ binding kinase	0.608
RNF11	ring finger protein 11	0.367
SMAD2	SMAD family member 2	0.283
BTRC	beta-transducin repeat containing	0.279
WNT3A	wingless-type MMTV integration site family, member 3A	0.278
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.266
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.208
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.187
SOX2	SRY (sex determining region Y)-box 2	0.187
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.183
ANKRD13A	ankyrin repeat domain 13A	0.178
ZNF148	zinc finger protein 148	0.157
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.145
SMAD6	SMAD family member 6	0.129
SMAD9	SMAD family member 9	0.123
ONECUT1	one cut homeobox 1	0.121
RBM17	RNA binding motif protein 17	0.117
WNT5A	wingless-type MMTV integration site family, member 5A	0.111
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.103
MTMR10	myotubularin related protein 10	0.099
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.095
SOX1	SRY (sex determining region Y)-box 1	0.085
SOX7	SRY (sex determining region Y)-box 7	0.080
TRAF4	TNF receptor-associated factor 4	0.075
FOXF2	forkhead box F2	0.070
ZMYM2	zinc finger, MYM-type 2	0.070
RBM4	RNA binding motif protein 4	0.068
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.068
FBXL15	F-box and leucine-rich repeat protein 15	0.061
NLK	nemo-like kinase	0.060
OTP	orthopedia homeobox	0.057
SOX9	SRY (sex determining region Y)-box 9	0.055
SCAF11	SR-related CTD-associated factor 11	0.054
FZD8	frizzled homolog 8 (Drosophila)	0.053
POU3F1	POU class 3 homeobox 1	0.052
FOXD3	forkhead box D3	0.052	Human
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.050
DNAJB14	DnaJ (Hsp40) homolog, subfamily B, member 14	0.047
INHBB	inhibin, beta B	0.046
PRRC1	proline-rich coiled-coil 1	0.046
FOXF1	forkhead box F1	0.043
FOXH1	forkhead box H1	0.043
SF3B14	splicing factor 3B, 14 kDa subunit	0.043
MNX1	motor neuron and pancreas homeobox 1	0.042
THAP2	THAP domain containing, apoptosis associated protein 2	0.042
CXXC5	CXXC finger protein 5	0.040
SPIN1	spindlin 1	0.039
SLC25A36	solute carrier family 25, member 36	0.039
ACBD3	acyl-CoA binding domain containing 3	0.038
MYST2	MYST histone acetyltransferase 2	0.038
PTF1A	pancreas specific transcription factor, 1a	0.037
GSC	goosecoid homeobox	0.036
HOXD9	homeobox D9	0.036
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.036
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.034	Human
FZD10	frizzled homolog 10 (Drosophila)	0.034
PITX2	paired-like homeodomain 2	0.034
EN2	engrailed homeobox 2	0.033
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.033
FOXB1	forkhead box B1	0.033
TNPO1	transportin 1	0.033
FGF8	fibroblast growth factor 8 (androgen-induced)	0.033
BBX	bobby sox homolog (Drosophila)	0.032
WT1	Wilms tumor 1	0.032
GATA4	GATA binding protein 4	0.031
HOXB13	homeobox B13	0.031
NET1	neuroepithelial cell transforming 1	0.031
ATF7IP	activating transcription factor 7 interacting protein	0.029
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.028
LHX1	LIM homeobox 1	0.028
EN1	engrailed homeobox 1	0.028
PDX1	pancreatic and duodenal homeobox 1	0.028
UTRN	utrophin	0.028
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.028
HIC1	hypermethylated in cancer 1	0.027
WNT1	wingless-type MMTV integration site family, member 1	0.027
HOXD1	homeobox D1	0.027
ZBED5	zinc finger, BED-type containing 5	0.027
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	0.027
POU4F2	POU class 4 homeobox 2	0.026
SP1	Sp1 transcription factor	0.026
SIM2	single-minded homolog 2 (Drosophila)	0.026
RBPMS	RNA binding protein with multiple splicing	0.026
PAX2	paired box 2	0.025
FOXD2	forkhead box D2	0.025	Human
NKX2-8	NK2 homeobox 8	0.025
LAPTM5	lysosomal protein transmembrane 5	0.025
NKX3-1	NK3 homeobox 1	0.024
PBX1	pre-B-cell leukemia homeobox 1	0.024
C5orf24	chromosome 5 open reading frame 24	0.024
COL2A1	collagen, type II, alpha 1	0.024
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.024
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.024
COL13A1	collagen, type XIII, alpha 1	0.024
HMX1	H6 family homeobox 1	0.024
PCYOX1	prenylcysteine oxidase 1	0.023
GDF7	growth differentiation factor 7	0.023
OTX2	orthodenticle homeobox 2	0.023
ARHGAP5	Rho GTPase activating protein 5	0.023
CDX2	caudal type homeobox 2	0.023
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.023
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.023
SOX5	SRY (sex determining region Y)-box 5	0.023
PYY	peptide YY	0.023
LBX1	ladybird homeobox 1	0.023
PAX7	paired box 7	0.023
HOXC13	homeobox C13	0.023
RMND5B	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.023
TBX1	T-box 1	0.022
NKX3-2	NK3 homeobox 2	0.022
FOXA1	forkhead box A1	0.022	Human
RYR2	ryanodine receptor 2 (cardiac)	0.021
PRKD3	protein kinase D3	0.021
HOXD13	homeobox D13	0.021
SIX6	SIX homeobox 6	0.021
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.021
KIAA1377	KIAA1377	0.020
FOXA2	forkhead box A2	0.020	Human
RBM19	RNA binding motif protein 19	0.020
PAX1	paired box 1	0.020
FOXL1	forkhead box L1	0.020	Human
CAPN9	calpain 9	0.020
DLX4	distal-less homeobox 4	0.020
PKN2	protein kinase N2	0.020
ACAN	aggrecan	0.020
IHH	Indian hedgehog	0.020
SIX2	SIX homeobox 2	0.020
DACH1	dachshund homolog 1 (Drosophila)	0.019
SYK	spleen tyrosine kinase	0.019
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.019
HES2	hairy and enhancer of split 2 (Drosophila)	0.019
DLX2	distal-less homeobox 2	0.019
FEV	FEV (ETS oncogene family)	0.019
UNCX	UNC homeobox	0.019
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.019
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.018
MAP2K2	mitogen-activated protein kinase kinase 2	0.018
NKX2-1	NK2 homeobox 1	0.018
PHF20L1	PHD finger protein 20-like 1	0.018
HOXB5	homeobox B5	0.018
VSX2	visual system homeobox 2	0.018
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.018
SNIP1	Smad nuclear interacting protein 1	0.018
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.018
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.018
STX16	syntaxin 16	0.018
FHL2	four and a half LIM domains 2	0.018
BCAR1	breast cancer anti-estrogen resistance 1	0.018
FOXC1	forkhead box C1	0.018	Human
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.018
OTOP3	otopetrin 3	0.018
HOXA11	homeobox A11	0.018
RYK	RYK receptor-like tyrosine kinase	0.018
VSX1	visual system homeobox 1	0.018
IRX5	iroquois homeobox 5	0.018
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.018
BARHL2	BarH-like homeobox 2	0.017
GATA2	GATA binding protein 2	0.017
VAX1	ventral anterior homeobox 1	0.017
NGF	nerve growth factor (beta polypeptide)	0.017
CHERP	calcium homeostasis endoplasmic reticulum protein	0.017
SFRP1	secreted frizzled-related protein 1	0.017
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.017
KIF3A	kinesin family member 3A	0.017
HMX3	H6 family homeobox 3	0.016
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.016
POU2F3	POU class 2 homeobox 3	0.016
HMGA2	high mobility group AT-hook 2	0.016
PAX6	paired box 6	0.016
SIKE1	suppressor of IKBKE 1	0.016
IL11	interleukin 11	0.016
HOXA13	homeobox A13	0.016
CA6	carbonic anhydrase VI	0.016
BHLHE23	basic helix-loop-helix family, member e23	0.016
BMP2	bone morphogenetic protein 2	0.016
VSTM2B	V-set and transmembrane domain containing 2B	0.016
NPTX1	neuronal pentraxin I	0.016
BNC1	basonuclin 1	0.016
WNT6	wingless-type MMTV integration site family, member 6	0.016
NRTN	neurturin	0.016
CD247	CD247 molecule	0.015
HOXD11	homeobox D11	0.015
HOXC8	homeobox C8	0.015
SH2D2A	SH2 domain containing 2A	0.015
SCARF2	scavenger receptor class F, member 2	0.015
SFRP5	secreted frizzled-related protein 5	0.015
SOX21	SRY (sex determining region Y)-box 21	0.015
NKX6-1	NK6 homeobox 1	0.015
FIBCD1	fibrinogen C domain containing 1	0.015
C1QL1	complement component 1, q subcomponent-like 1	0.015
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.015
TP73	tumor protein p73	0.015
GATA6	GATA binding protein 6	0.015
ONECUT2	one cut homeobox 2	0.015
TBX2	T-box 2	0.015
ADRB1	adrenergic, beta-1-, receptor	0.015
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.015
HNF1B	HNF1 homeobox B	0.015
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.015
HOXA10	homeobox A10	0.015
TMPRSS2	transmembrane protease, serine 2	0.015
FOXI2	forkhead box I2	0.015	Human
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.015
EFNB3	ephrin-B3	0.014
AMN	amnionless homolog (mouse)	0.014
GATA5	GATA binding protein 5	0.014
USH1G	Usher syndrome 1G (autosomal recessive)	0.014
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.014
PRKCQ	protein kinase C, theta	0.014
SALL4	sal-like 4 (Drosophila)	0.014
WNT10A	wingless-type MMTV integration site family, member 10A	0.014
PARVA	parvin, alpha	0.014
HOXC11	homeobox C11	0.014
HMX2	H6 family homeobox 2	0.014
LHX2	LIM homeobox 2	0.014
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.014
HOXD3	homeobox D3	0.014
PRRX2	paired related homeobox 2	0.014
SHOX2	short stature homeobox 2	0.014
SOX3	SRY (sex determining region Y)-box 3	0.014
MYOD1	myogenic differentiation 1	0.014
NKX2-4	NK2 homeobox 4	0.014
DMRT1	doublesex and mab-3 related transcription factor 1	0.014
ETV7	ets variant 7	0.014
PITX1	paired-like homeodomain 1	0.014
VWC2	von Willebrand factor C domain containing 2	0.014
C5orf38	chromosome 5 open reading frame 38	0.014
PXN	paxillin	0.014
VAX2	ventral anterior homeobox 2	0.014
ITGB8	integrin, beta 8	0.014
PTEN	phosphatase and tensin homolog	0.013
EFNA2	ephrin-A2	0.013
TCF15	transcription factor 15 (basic helix-loop-helix)	0.013
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.013
FOXB2	forkhead box B2	0.013	Human
C17orf102	chromosome 17 open reading frame 102	0.013
HOXB9	homeobox B9	0.013
HDLBP	high density lipoprotein binding protein	0.013
FOXD1	forkhead box D1	0.013
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.013
AQP5	aquaporin 5	0.013
HOXB6	homeobox B6	0.013
SOX17	SRY (sex determining region Y)-box 17	0.013
POU3F2	POU class 3 homeobox 2	0.013
PDLIM4	PDZ and LIM domain 4	0.013
OPRD1	opioid receptor, delta 1	0.013
CYP26C1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.013
DMRT3	doublesex and mab-3 related transcription factor 3	0.013
FAM83E	family with sequence similarity 83, member E	0.013
GPC4	glypican 4	0.013
ICK	intestinal cell (MAK-like) kinase	0.013
SIX1	SIX homeobox 1	0.013
POU4F3	POU class 4 homeobox 3	0.013
CRLF1	cytokine receptor-like factor 1	0.013
EMX1	empty spiracles homeobox 1	0.013
TWIST2	twist homolog 2 (Drosophila)	0.012
MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.012
SPAG9	sperm associated antigen 9	0.012
SP5	Sp5 transcription factor	0.012
GPS2	G protein pathway suppressor 2	0.012
SOX18	SRY (sex determining region Y)-box 18	0.012
CRHR1	corticotropin releasing hormone receptor 1	0.012
ZBTB38	zinc finger and BTB domain containing 38	0.012
EVX2	even-skipped homeobox 2	0.012
MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2	0.012
FOXD4L6	forkhead box D4-like 6	0.012	Human
ARX	aristaless related homeobox	0.012
SALL3	sal-like 3 (Drosophila)	0.012
NKX2-2	NK2 homeobox 2	0.012
HOXB3	homeobox B3	0.012
ATOH1	atonal homolog 1 (Drosophila)	0.012
ISL2	ISL LIM homeobox 2	0.012
AGFG2	ArfGAP with FG repeats 2	0.012
JPH3	junctophilin 3	0.012
SPDEF	SAM pointed domain containing ets transcription factor	0.012
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.012
HOXB8	homeobox B8	0.012
SKOR1	SKI family transcriptional corepressor 1	0.012
SEZ6L2	seizure related 6 homolog (mouse)-like 2	0.012
EYA2	eyes absent homolog 2 (Drosophila)	0.012
PCDH8	protocadherin 8	0.012
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.012
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.012
SCRT2	scratch homolog 2, zinc finger protein (Drosophila)	0.012
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.012
WNT5B	wingless-type MMTV integration site family, member 5B	0.012
MAST4	microtubule associated serine/threonine kinase family member 4	0.011
BARX1	BARX homeobox 1	0.011
CST1	cystatin SN	0.011
HOXD12	homeobox D12	0.011
MSX1	msh homeobox 1	0.011
DIO3	deiodinase, iodothyronine, type III	0.011
TRIM37	tripartite motif containing 37	0.011
PIAS1	protein inhibitor of activated STAT, 1	0.011
FLNB	filamin B, beta	0.011
OVOL2	ovo-like 2 (Drosophila)	0.011
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.011
IRX4	iroquois homeobox 4	0.011
INSM1	insulinoma-associated 1	0.011
EVX1	even-skipped homeobox 1	0.011
PRDM16	PR domain containing 16	0.011
IRX1	iroquois homeobox 1	0.011
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.011
C8orf84	chromosome 8 open reading frame 84	0.011
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.011
DAZAP2	DAZ associated protein 2	0.011
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.011
NOVA2	neuro-oncological ventral antigen 2	0.011
CALCA	calcitonin-related polypeptide alpha	0.011
CD70	CD70 molecule	0.011
AJAP1	adherens junctions associated protein 1	0.011
SFPQ	splicing factor proline/glutamine-rich	0.011
PRDM13	PR domain containing 13	0.011
GSC2	goosecoid homeobox 2	0.011
HOXA3	homeobox A3	0.011
HOXC12	homeobox C12	0.011
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.011
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
HES5	hairy and enhancer of split 5 (Drosophila)	0.011
NEUROD1	neurogenic differentiation 1	0.011
KREMEN2	kringle containing transmembrane protein 2	0.011
BMP8A	bone morphogenetic protein 8a	0.011
FOXL2	forkhead box L2	0.011	Human
TRNP1	TMF1-regulated nuclear protein 1	0.011
ZNF503	zinc finger protein 503	0.011
COL8A2	collagen, type VIII, alpha 2	0.011
SALL1	sal-like 1 (Drosophila)	0.011
FGF5	fibroblast growth factor 5	0.011
HES3	hairy and enhancer of split 3 (Drosophila)	0.011
OTOP1	otopetrin 1	0.011
FGF18	fibroblast growth factor 18	0.011
FGFR1	fibroblast growth factor receptor 1	0.011
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.011
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.010
BDNF	brain-derived neurotrophic factor	0.010
CUEDC1	CUE domain containing 1	0.010
FOXQ1	forkhead box Q1	0.010	Human
SREK1IP1	SREK1-interacting protein 1	0.010
IRX2	iroquois homeobox 2	0.010
KLF2	Kruppel-like factor 2 (lung)	0.010
COL11A1	collagen, type XI, alpha 1	0.010
LHX5	LIM homeobox 5	0.010
ALOX15	arachidonate 15-lipoxygenase	0.010
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.010
TMEM139	transmembrane protein 139	0.010
GJA3	gap junction protein, alpha 3, 46kDa	0.010
RUNX2	runt-related transcription factor 2	0.010
OTX1	orthodenticle homeobox 1	0.010
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.010
DBX1	developing brain homeobox 1	0.010
GAL	galanin prepropeptide	0.010
POU3F3	POU class 3 homeobox 3	0.010
TGFBR1	transforming growth factor, beta receptor 1	0.010
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.010
TPM1	tropomyosin 1 (alpha)	0.010
PCDH7	protocadherin 7	0.010
WNT3	wingless-type MMTV integration site family, member 3	0.010
MKL2	MKL/myocardin-like 2	0.010
SIX3	SIX homeobox 3	0.010
MSX2	msh homeobox 2	0.010
NEUROG3	neurogenin 3	0.010
HCRTR1	hypocretin (orexin) receptor 1	0.010
FGFR4	fibroblast growth factor receptor 4	0.010
BMP4	bone morphogenetic protein 4	0.010
GMEB1	glucocorticoid modulatory element binding protein 1	0.010
PHF1	PHD finger protein 1	0.010
PROX1	prospero homeobox 1	0.010
DSCR6	Down syndrome critical region gene 6	0.010
TBX3	T-box 3	0.010