Saccharomyces cerevisiae

41 known processes

PRP8 (YHR165C)

Prp8p

(Aliases: USA2,DBF3,SLT21,DNA39,RNA8)

PRP8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing via transesterification reactions GO:0000375 118 1.000
mrna splicing via spliceosome GO:0000398 108 1.000
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 1.000
mrna processing GO:0006397 185 1.000
rna splicing GO:0008380 131 1.000
mrna metabolic process GO:0016071 269 1.000
spliceosomal conformational changes to generate catalytic conformation GO:0000393 20 0.999
ribonucleoprotein complex subunit organization GO:0071826 152 0.980
ribonucleoprotein complex assembly GO:0022618 143 0.945
spliceosomal complex assembly GO:0000245 21 0.804
generation of catalytic spliceosome for first transesterification step GO:0000349 9 0.736
generation of catalytic spliceosome for second transesterification step GO:0000350 9 0.609
developmental process GO:0032502 261 0.581
Worm Fly
spliceosomal snrnp assembly GO:0000387 6 0.528
spliceosomal tri snrnp complex assembly GO:0000244 4 0.442
regulation of meiosis GO:0040020 42 0.405
atp metabolic process GO:0046034 251 0.405
organelle fission GO:0048285 272 0.403
regulation of cell division GO:0051302 113 0.402
regulation of cell cycle GO:0051726 195 0.394
nucleoside triphosphate metabolic process GO:0009141 364 0.387
purine ribonucleoside metabolic process GO:0046128 380 0.377
nucleoside monophosphate metabolic process GO:0009123 267 0.363
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.356
regulation of nuclear division GO:0051783 103 0.353
cell division GO:0051301 205 0.327
purine nucleotide metabolic process GO:0006163 376 0.326
nucleoside triphosphate catabolic process GO:0009143 329 0.318
negative regulation of gene expression GO:0010629 312 0.316
regulation of cell cycle process GO:0010564 150 0.305
nuclear division GO:0000280 263 0.296
nucleotide catabolic process GO:0009166 330 0.268
single organism developmental process GO:0044767 258 0.266
Worm Fly
ribonucleoside catabolic process GO:0042454 332 0.260
ribonucleoside triphosphate metabolic process GO:0009199 356 0.258
ribonucleoside triphosphate catabolic process GO:0009203 327 0.224
purine containing compound catabolic process GO:0072523 332 0.218
meiotic nuclear division GO:0007126 163 0.213
purine ribonucleoside catabolic process GO:0046130 330 0.211
nucleoside metabolic process GO:0009116 394 0.201
nucleotide metabolic process GO:0009117 453 0.201
regulation of cellular component organization GO:0051128 334 0.196
negative regulation of macromolecule metabolic process GO:0010605 375 0.193
regulation of organelle organization GO:0033043 243 0.192
carbohydrate derivative metabolic process GO:1901135 549 0.191
purine ribonucleotide catabolic process GO:0009154 327 0.189
nucleoside catabolic process GO:0009164 335 0.187
meiotic cell cycle GO:0051321 272 0.185
nucleobase containing compound catabolic process GO:0034655 479 0.178
nucleoside phosphate catabolic process GO:1901292 331 0.177
regulation of meiotic cell cycle GO:0051445 43 0.177
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.176
mitotic cell cycle GO:0000278 306 0.176
protein complex assembly GO:0006461 302 0.160
purine nucleoside monophosphate metabolic process GO:0009126 262 0.156
cellular component movement GO:0006928 20 0.147
Worm
cellular response to dna damage stimulus GO:0006974 287 0.144
cellular nitrogen compound catabolic process GO:0044270 494 0.141
cellular developmental process GO:0048869 191 0.139
Fly
growth GO:0040007 157 0.138
mitotic nuclear division GO:0007067 131 0.138
organophosphate metabolic process GO:0019637 597 0.134
organophosphate catabolic process GO:0046434 338 0.132
purine nucleoside catabolic process GO:0006152 330 0.125
organonitrogen compound catabolic process GO:1901565 404 0.124
carbohydrate derivative catabolic process GO:1901136 339 0.123
purine nucleoside monophosphate catabolic process GO:0009128 224 0.114
purine nucleoside triphosphate catabolic process GO:0009146 329 0.109
purine containing compound metabolic process GO:0072521 400 0.109
macromolecular complex disassembly GO:0032984 80 0.109
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.099
regulation of mrna splicing via spliceosome GO:0048024 3 0.099
aromatic compound catabolic process GO:0019439 491 0.098
ribonucleoside monophosphate catabolic process GO:0009158 224 0.097
cellular component assembly involved in morphogenesis GO:0010927 73 0.096
cell development GO:0048468 107 0.095
glycosyl compound metabolic process GO:1901657 398 0.095
mitotic cell cycle process GO:1903047 294 0.094
ribonucleoside metabolic process GO:0009119 389 0.087
anatomical structure formation involved in morphogenesis GO:0048646 136 0.084
nucleoside monophosphate catabolic process GO:0009125 224 0.081
glycosyl compound catabolic process GO:1901658 335 0.068
vesicle mediated transport GO:0016192 335 0.066
Worm
negative regulation of rna metabolic process GO:0051253 262 0.061
single organism catabolic process GO:0044712 619 0.060
mrna splice site selection GO:0006376 8 0.057
cellular component morphogenesis GO:0032989 97 0.055
cell differentiation GO:0030154 161 0.049
Fly
ncrna processing GO:0034470 330 0.048
rrna processing GO:0006364 227 0.046
negative regulation of transcription dna templated GO:0045892 258 0.044
signal transduction GO:0007165 208 0.041
anatomical structure morphogenesis GO:0009653 160 0.040
signaling GO:0023052 208 0.039
negative regulation of rna biosynthetic process GO:1902679 260 0.039
single organism membrane organization GO:0044802 275 0.036
establishment of protein localization to membrane GO:0090150 99 0.036
purine nucleoside triphosphate metabolic process GO:0009144 356 0.036
protein complex biogenesis GO:0070271 314 0.035
oxidation reduction process GO:0055114 353 0.034
negative regulation of nucleic acid templated transcription GO:1903507 260 0.033
chromatin modification GO:0016568 200 0.033
cellular response to extracellular stimulus GO:0031668 150 0.032
cell communication GO:0007154 345 0.031
negative regulation of cellular metabolic process GO:0031324 407 0.028
anatomical structure development GO:0048856 160 0.028
Worm Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.027
regulation of dna metabolic process GO:0051052 100 0.027
cellular bud site selection GO:0000282 35 0.027
chromatin organization GO:0006325 242 0.026
dna replication GO:0006260 147 0.026
posttranscriptional regulation of gene expression GO:0010608 115 0.026
rrna metabolic process GO:0016072 244 0.025
ribose phosphate metabolic process GO:0019693 384 0.025
snorna metabolic process GO:0016074 40 0.025
negative regulation of biosynthetic process GO:0009890 312 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
ribonucleoside monophosphate metabolic process GO:0009161 265 0.023
translation GO:0006412 230 0.023
atp catabolic process GO:0006200 224 0.023
ribonucleoprotein complex disassembly GO:0032988 11 0.022
cell cycle phase transition GO:0044770 144 0.021
cellular component disassembly GO:0022411 86 0.021
ribosome biogenesis GO:0042254 335 0.021
mitotic cell cycle phase transition GO:0044772 141 0.021
maturation of lsu rrna GO:0000470 39 0.020
negative regulation of cellular biosynthetic process GO:0031327 312 0.019
cellular macromolecule catabolic process GO:0044265 363 0.019
small molecule biosynthetic process GO:0044283 258 0.018
cotranslational protein targeting to membrane GO:0006613 15 0.018
membrane organization GO:0061024 276 0.018
carbohydrate biosynthetic process GO:0016051 82 0.017
protein polyubiquitination GO:0000209 20 0.016
response to external stimulus GO:0009605 158 0.016
purine ribonucleotide metabolic process GO:0009150 372 0.016
ribosomal small subunit biogenesis GO:0042274 124 0.016
snorna processing GO:0043144 34 0.016
organic acid biosynthetic process GO:0016053 152 0.016
actin cytoskeleton organization GO:0030036 100 0.016
cytoskeleton dependent cytokinesis GO:0061640 65 0.015
carboxylic acid biosynthetic process GO:0046394 152 0.014
protein localization to endoplasmic reticulum GO:0070972 47 0.014
cellular amino acid metabolic process GO:0006520 225 0.014
ribonucleotide metabolic process GO:0009259 377 0.014
rna 5 end processing GO:0000966 33 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.014
purine nucleotide catabolic process GO:0006195 328 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.014
intracellular signal transduction GO:0035556 112 0.013
protein targeting to er GO:0045047 39 0.013
regulation of response to drug GO:2001023 3 0.013
covalent chromatin modification GO:0016569 119 0.013
establishment of protein localization to endoplasmic reticulum GO:0072599 40 0.013
endocytosis GO:0006897 90 0.013
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.013
regulation of cellular protein metabolic process GO:0032268 232 0.013
negative regulation of organelle organization GO:0010639 103 0.012
establishment of protein localization GO:0045184 367 0.012
ribonucleotide catabolic process GO:0009261 327 0.012
response to organic cyclic compound GO:0014070 1 0.012
response to abiotic stimulus GO:0009628 159 0.012
regulation of biological quality GO:0065008 391 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.011
cellular response to chemical stimulus GO:0070887 315 0.011
regulation of catabolic process GO:0009894 199 0.011
mrna cis splicing via spliceosome GO:0045292 4 0.011
mitotic cytokinesis site selection GO:1902408 35 0.011
g1 s transition of mitotic cell cycle GO:0000082 64 0.011
chromatin remodeling GO:0006338 80 0.011
positive regulation of ethanol catabolic process GO:1900066 1 0.011
gene silencing GO:0016458 151 0.011
regulation of cell cycle phase transition GO:1901987 70 0.010
posttranslational protein targeting to membrane GO:0006620 17 0.010
single organism signaling GO:0044700 208 0.010
regulation of mrna metabolic process GO:1903311 17 0.010
organic acid metabolic process GO:0006082 352 0.010
cell cycle g2 m phase transition GO:0044839 39 0.010
regulation of translation GO:0006417 89 0.010
nucleobase containing small molecule metabolic process GO:0055086 491 0.010
regulation of mitotic cell cycle GO:0007346 107 0.010
mitotic cytokinesis GO:0000281 58 0.010
regulation of cellular catabolic process GO:0031329 195 0.010
establishment of cell polarity GO:0030010 64 0.010
reproductive process GO:0022414 248 0.010
Worm
protein targeting to membrane GO:0006612 52 0.010

PRP8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
nervous system disease DOID:863 0 0.034
Human
sensory system disease DOID:0050155 0 0.024
Human
eye and adnexa disease DOID:1492 0 0.024
Human
eye disease DOID:5614 0 0.010
Human
retinal disease DOID:5679 0 0.010
Human