Saccharomyces cerevisiae

85 known processes

SMC3 (YJL074C)

Smc3p

SMC3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid segregation GO:0000070 85 0.993
sister chromatid segregation GO:0000819 93 0.992
chromosome segregation GO:0007059 159 0.990
nuclear division GO:0000280 263 0.980
mitotic sister chromatid cohesion GO:0007064 38 0.853
organelle fission GO:0048285 272 0.833
chromosome condensation GO:0030261 19 0.789
Worm
double strand break repair GO:0006302 105 0.784
mitotic chromosome condensation GO:0007076 11 0.735
dna conformation change GO:0071103 98 0.722
Worm
sister chromatid cohesion GO:0007062 49 0.643
dna packaging GO:0006323 55 0.641
Worm
negative regulation of gene expression GO:0010629 312 0.586
mitotic cell cycle GO:0000278 306 0.551
mitotic nuclear division GO:0007067 131 0.527
positive regulation of macromolecule metabolic process GO:0010604 394 0.503
mitotic cell cycle process GO:1903047 294 0.495
regulation of cell division GO:0051302 113 0.474
meiotic cell cycle GO:0051321 272 0.424
regulation of cellular protein metabolic process GO:0032268 232 0.420
regulation of protein metabolic process GO:0051246 237 0.366
negative regulation of cellular metabolic process GO:0031324 407 0.363
Human
protein localization to organelle GO:0033365 337 0.355
regulation of cell cycle process GO:0010564 150 0.343
Human
cellular response to dna damage stimulus GO:0006974 287 0.313
meiotic nuclear division GO:0007126 163 0.300
negative regulation of macromolecule metabolic process GO:0010605 375 0.286
Human
regulation of cellular component organization GO:0051128 334 0.272
establishment of protein localization GO:0045184 367 0.269
recombinational repair GO:0000725 64 0.245
regulation of organelle organization GO:0033043 243 0.239
negative regulation of cell cycle process GO:0010948 86 0.208
Human
dna repair GO:0006281 236 0.205
regulation of nuclear division GO:0051783 103 0.202
establishment of protein localization to organelle GO:0072594 278 0.179
dna replication GO:0006260 147 0.169
Human
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.168
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.158
dna duplex unwinding GO:0032508 42 0.151
single organism cellular localization GO:1902580 375 0.138
negative regulation of rna metabolic process GO:0051253 262 0.137
establishment of mitotic sister chromatid cohesion GO:0034087 15 0.132
dna recombination GO:0006310 172 0.132
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.132
Human
protein transport GO:0015031 345 0.120
regulation of protein modification process GO:0031399 110 0.115
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.110
Human
dna dependent dna replication GO:0006261 115 0.105
Human
cell division GO:0051301 205 0.102
Worm
negative regulation of organelle organization GO:0010639 103 0.099
organic cyclic compound catabolic process GO:1901361 499 0.098
negative regulation of nuclear division GO:0051784 62 0.096
positive regulation of gene expression GO:0010628 321 0.095
cellular macromolecule catabolic process GO:0044265 363 0.093
regulation of dna metabolic process GO:0051052 100 0.090
Human
gene silencing GO:0016458 151 0.089
negative regulation of cell cycle GO:0045786 91 0.083
Human
regulation of meiosis GO:0040020 42 0.083
negative regulation of biosynthetic process GO:0009890 312 0.078
Human
regulation of gene expression epigenetic GO:0040029 147 0.078
double strand break repair via homologous recombination GO:0000724 54 0.077
cell cycle checkpoint GO:0000075 82 0.072
nucleobase containing compound catabolic process GO:0034655 479 0.070
meiotic cell cycle process GO:1903046 229 0.069
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.068
positive regulation of transcription dna templated GO:0045893 286 0.064
regulation of cell cycle GO:0051726 195 0.063
Human
dna geometric change GO:0032392 43 0.063
cell communication GO:0007154 345 0.062
Human
heterocycle catabolic process GO:0046700 494 0.062
organelle assembly GO:0070925 118 0.061
negative regulation of cell division GO:0051782 66 0.059
protein catabolic process GO:0030163 221 0.059
aromatic compound catabolic process GO:0019439 491 0.058
meiosis i GO:0007127 92 0.058
regulation of chromosome organization GO:0033044 66 0.057
organophosphate catabolic process GO:0046434 338 0.052
cell cycle phase transition GO:0044770 144 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.048
regulation of mitotic cell cycle GO:0007346 107 0.048
macromolecule catabolic process GO:0009057 383 0.048
organelle localization GO:0051640 128 0.047
mitotic sister chromatid separation GO:0051306 26 0.045
regulation of mitotic sister chromatid segregation GO:0033047 30 0.044
nuclear transport GO:0051169 165 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.043
negative regulation of gene expression epigenetic GO:0045814 147 0.042
nucleocytoplasmic transport GO:0006913 163 0.042
single organism catabolic process GO:0044712 619 0.042
positive regulation of biosynthetic process GO:0009891 336 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.041
establishment of sister chromatid cohesion GO:0034085 17 0.040
dna unwinding involved in dna replication GO:0006268 13 0.040
regulation of cell cycle phase transition GO:1901987 70 0.039
rna phosphodiester bond hydrolysis GO:0090501 112 0.038
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.037
regulation of biological quality GO:0065008 391 0.036
ubiquitin dependent protein catabolic process GO:0006511 181 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.035
Human
regulation of mitosis GO:0007088 65 0.034
regulation of dna replication GO:0006275 51 0.034
Human
chromatin organization GO:0006325 242 0.033
cellular nitrogen compound catabolic process GO:0044270 494 0.032
mitotic cell cycle checkpoint GO:0007093 56 0.031
regulation of meiotic cell cycle GO:0051445 43 0.031
negative regulation of mitosis GO:0045839 39 0.031
mitotic spindle assembly checkpoint GO:0007094 23 0.030
positive regulation of rna metabolic process GO:0051254 294 0.030
ribonucleotide catabolic process GO:0009261 327 0.029
organonitrogen compound catabolic process GO:1901565 404 0.028
negative regulation of rna biosynthetic process GO:1902679 260 0.028
meiotic chromosome segregation GO:0045132 31 0.028
mitotic cell cycle phase transition GO:0044772 141 0.028
metaphase anaphase transition of cell cycle GO:0044784 28 0.027
negative regulation of mitotic sister chromatid segregation GO:0033048 24 0.027
cytoskeleton organization GO:0007010 230 0.027
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.026
protein localization to chromosome GO:0034502 28 0.025
cellular protein catabolic process GO:0044257 213 0.025
spindle organization GO:0007051 37 0.025
Human
multi organism reproductive process GO:0044703 216 0.024
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.024
regulation of catabolic process GO:0009894 199 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.023
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.023
regulation of mitotic cell cycle phase transition GO:1901990 68 0.023
single organism signaling GO:0044700 208 0.022
Human
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.022
purine nucleoside triphosphate metabolic process GO:0009144 356 0.022
chromosome organization involved in meiosis GO:0070192 32 0.022
positive regulation of cellular biosynthetic process GO:0031328 336 0.021
regulation of mitotic sister chromatid separation GO:0010965 29 0.021
sexual reproduction GO:0019953 216 0.021
negative regulation of transcription dna templated GO:0045892 258 0.020
negative regulation of nucleic acid templated transcription GO:1903507 260 0.020
carbohydrate derivative metabolic process GO:1901135 549 0.020
chromatin silencing at telomere GO:0006348 84 0.020
positive regulation of cellular protein metabolic process GO:0032270 89 0.019
protein modification by small protein conjugation or removal GO:0070647 172 0.019
translation GO:0006412 230 0.019
posttranscriptional regulation of gene expression GO:0010608 115 0.019
negative regulation of mitotic cell cycle GO:0045930 63 0.019
ribonucleoside triphosphate catabolic process GO:0009203 327 0.018
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.018
death GO:0016265 30 0.018
peptidyl amino acid modification GO:0018193 116 0.017
regulation of molecular function GO:0065009 320 0.017
regulation of cellular catabolic process GO:0031329 195 0.017
nucleoside catabolic process GO:0009164 335 0.017
signal transduction GO:0007165 208 0.016
Human
purine ribonucleoside catabolic process GO:0046130 330 0.015
positive regulation of cellular component organization GO:0051130 116 0.015
apoptotic process GO:0006915 30 0.014
organophosphate metabolic process GO:0019637 597 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
negative regulation of cellular component organization GO:0051129 109 0.014
microtubule cytoskeleton organization GO:0000226 109 0.013
Human
positive regulation of nucleic acid templated transcription GO:1903508 286 0.013
nucleoside monophosphate metabolic process GO:0009123 267 0.013
protein import GO:0017038 122 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
rna catabolic process GO:0006401 118 0.012
vesicle mediated transport GO:0016192 335 0.012
Worm
chromosome separation GO:0051304 33 0.012
regulation of cellular component biogenesis GO:0044087 112 0.012
signaling GO:0023052 208 0.012
Human
response to uv GO:0009411 4 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.012
intracellular protein transport GO:0006886 319 0.012
glycosyl compound catabolic process GO:1901658 335 0.012
peptidyl lysine modification GO:0018205 77 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.011
chromatin silencing GO:0006342 147 0.011
positive regulation of protein metabolic process GO:0051247 93 0.011
purine nucleoside triphosphate catabolic process GO:0009146 329 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.011
dna integrity checkpoint GO:0031570 41 0.010
modification dependent macromolecule catabolic process GO:0043632 203 0.010
nucleotide catabolic process GO:0009166 330 0.010
covalent chromatin modification GO:0016569 119 0.010
regulation of phosphate metabolic process GO:0019220 230 0.010

SMC3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org