Drosophila melanogaster

111 known processes

MBD-R2 (Dmel_CG10042)

CG10042 gene product from transcript CG10042-RB

(Aliases: MBD,MBDR2,CG10042,TAM3,Dm Tam3,CG17393,dMBD-R2,Dmel\CG10042)

MBD-R2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 223 0.520
g2 dna damage checkpoint GO:0031572 69 0.402
centrosome organization GO:0051297 163 0.314
mitotic dna damage checkpoint GO:0044773 74 0.303
mrna metabolic process GO:0016071 124 0.271
positive regulation of macromolecule metabolic process GO:0010604 405 0.239
regulation of cell cycle phase transition GO:1901987 130 0.232
chromatin organization GO:0006325 207 0.230
negative regulation of cell cycle phase transition GO:1901988 103 0.212
cellular protein modification process GO:0006464 438 0.194
microtubule organizing center organization GO:0031023 168 0.183
chromosome organization GO:0051276 360 0.153
mitotic cell cycle phase transition GO:0044772 138 0.138
cell cycle phase transition GO:0044770 140 0.133
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.124
protein modification process GO:0036211 438 0.120
body morphogenesis GO:0010171 2 0.116
negative regulation of cell cycle GO:0045786 116 0.098
regulation of cell cycle process GO:0010564 181 0.098
covalent chromatin modification GO:0016569 106 0.097
ras protein signal transduction GO:0007265 88 0.095
chromatin remodeling GO:0006338 72 0.094
regulation of small gtpase mediated signal transduction GO:0051056 93 0.089
chromatin modification GO:0016568 147 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.089
negative regulation of cell cycle process GO:0010948 109 0.085
histone modification GO:0016570 106 0.083
aromatic compound catabolic process GO:0019439 166 0.080
catabolic process GO:0009056 409 0.076
regulation of mitotic cell cycle phase transition GO:1901990 130 0.073
negative regulation of cellular metabolic process GO:0031324 382 0.072
small gtpase mediated signal transduction GO:0007264 88 0.070
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.069
heterocycle catabolic process GO:0046700 166 0.064
dendrite development GO:0016358 204 0.063
organic substance catabolic process GO:1901575 308 0.062
mitotic dna integrity checkpoint GO:0044774 75 0.061
regulation of ras protein signal transduction GO:0046578 93 0.060
nucleobase containing compound catabolic process GO:0034655 165 0.057
cellular nitrogen compound catabolic process GO:0044270 165 0.055
mitotic g2 dna damage checkpoint GO:0007095 69 0.053
cell cycle checkpoint GO:0000075 95 0.051
cellular catabolic process GO:0044248 372 0.049
rna processing GO:0006396 147 0.049
cellular macromolecule catabolic process GO:0044265 136 0.047
spindle elongation GO:0051231 83 0.045
regulation of neuron differentiation GO:0045664 103 0.045
regulation of nervous system development GO:0051960 248 0.040
regulation of neurogenesis GO:0050767 158 0.040
regulation of multicellular organismal development GO:2000026 414 0.040
regulation of chromosome organization GO:0033044 64 0.039
dna damage checkpoint GO:0000077 78 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.037
purine containing compound metabolic process GO:0072521 155 0.037
negative regulation of rna metabolic process GO:0051253 251 0.036
regulation of mitotic cell cycle GO:0007346 190 0.036
glycosyl compound catabolic process GO:1901658 112 0.034
organelle fission GO:0048285 340 0.034
cell proliferation GO:0008283 299 0.033
cytoplasmic transport GO:0016482 130 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.033
centrosome duplication GO:0051298 121 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
immune system process GO:0002376 347 0.032
regulation of cellular protein metabolic process GO:0032268 243 0.032
phosphorylation GO:0016310 294 0.032
telomere organization GO:0032200 21 0.032
mitotic cell cycle checkpoint GO:0007093 88 0.032
dna biosynthetic process GO:0071897 24 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
regulation of molecular function GO:0065009 217 0.030
regulation of cell cycle GO:0051726 291 0.030
purine nucleotide metabolic process GO:0006163 146 0.029
ribonucleoside catabolic process GO:0042454 112 0.029
regulation of phosphorylation GO:0042325 147 0.029
mitotic spindle elongation GO:0000022 81 0.029
dna replication GO:0006260 48 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.028
regulation of mrna processing GO:0050684 71 0.028
peptidyl amino acid modification GO:0018193 105 0.027
protein localization GO:0008104 284 0.027
anatomical structure homeostasis GO:0060249 97 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
purine nucleotide catabolic process GO:0006195 109 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
nuclear division GO:0000280 332 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
centrosome cycle GO:0007098 137 0.025
axon development GO:0061564 297 0.024
ribonucleoside monophosphate catabolic process GO:0009158 39 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
proteolysis GO:0006508 192 0.024
glycosyl compound metabolic process GO:1901657 127 0.023
spindle organization GO:0007051 253 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
regulation of cell development GO:0060284 215 0.023
phagocytosis GO:0006909 215 0.023
establishment of localization in cell GO:0051649 402 0.023
rna polyadenylation GO:0043631 12 0.023
purine nucleoside catabolic process GO:0006152 112 0.022
dna repair GO:0006281 54 0.022
protein ubiquitination GO:0016567 70 0.022
multi multicellular organism process GO:0044706 123 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
nucleoside metabolic process GO:0009116 127 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
telomere maintenance GO:0000723 21 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
protein catabolic process GO:0030163 101 0.020
purine nucleoside metabolic process GO:0042278 127 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
organophosphate metabolic process GO:0019637 195 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
dna integrity checkpoint GO:0031570 81 0.020
aging GO:0007568 143 0.020
intracellular signal transduction GO:0035556 300 0.019
nucleotide catabolic process GO:0009166 109 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
positive regulation of catabolic process GO:0009896 105 0.018
sex differentiation GO:0007548 81 0.017
axonogenesis GO:0007409 290 0.017
regulation of localization GO:0032879 275 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
male gamete generation GO:0048232 201 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
positive regulation of gene expression GO:0010628 290 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
central nervous system development GO:0007417 201 0.016
dendrite morphogenesis GO:0048813 199 0.016
regulation of neuron projection development GO:0010975 69 0.016
regulation of cell proliferation GO:0042127 163 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
erk1 and erk2 cascade GO:0070371 39 0.016
nucleocytoplasmic transport GO:0006913 72 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
protein complex biogenesis GO:0070271 201 0.016
regulation of protein modification process GO:0031399 112 0.016
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
multicellular organismal aging GO:0010259 140 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
peptide metabolic process GO:0006518 80 0.015
dna metabolic process GO:0006259 227 0.015
ribonucleoside monophosphate metabolic process GO:0009161 51 0.015
regulation of catabolic process GO:0009894 170 0.015
response to organic substance GO:0010033 284 0.015
cellular amide metabolic process GO:0043603 80 0.015
negative regulation of cell differentiation GO:0045596 143 0.014
cellular macromolecule localization GO:0070727 220 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of erk1 and erk2 cascade GO:0070372 39 0.014
single organism catabolic process GO:0044712 228 0.014
macromolecule catabolic process GO:0009057 161 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
regulation of intracellular protein transport GO:0033157 46 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
positive regulation of cell communication GO:0010647 250 0.013
positive regulation of signaling GO:0023056 243 0.013
protein dna complex subunit organization GO:0071824 86 0.013
rna 3 end processing GO:0031123 45 0.013
protein processing GO:0016485 68 0.013
atp metabolic process GO:0046034 49 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
negative regulation of cell communication GO:0010648 223 0.013
mrna processing GO:0006397 104 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
protein complex assembly GO:0006461 200 0.012
anterior posterior pattern specification GO:0009952 136 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
macromolecular complex assembly GO:0065003 256 0.012
photoreceptor cell development GO:0042461 96 0.012
atp dependent chromatin remodeling GO:0043044 22 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
hematopoietic stem cell differentiation GO:0060218 1 0.012
regulation of dna repair GO:0006282 5 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 0 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
negative regulation of developmental process GO:0051093 201 0.012
brain development GO:0007420 120 0.012
cell death GO:0008219 279 0.012
centriole replication GO:0007099 24 0.011
small molecule metabolic process GO:0044281 305 0.011
regulation of apoptotic process GO:0042981 130 0.011
cellular component disassembly GO:0022411 46 0.011
cellular protein localization GO:0034613 160 0.011
regulation of cell death GO:0010941 173 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
intracellular transport GO:0046907 228 0.011
protein phosphorylation GO:0006468 169 0.011
regulation of catalytic activity GO:0050790 185 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
rrna processing GO:0006364 3 0.011
response to oxygen containing compound GO:1901700 200 0.011
macromolecule methylation GO:0043414 45 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
ubiquitin homeostasis GO:0010992 1 0.011
cell maturation GO:0048469 144 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
muscle structure development GO:0061061 224 0.010
multicellular organism growth GO:0035264 46 0.010
eye photoreceptor cell development GO:0042462 81 0.010

MBD-R2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.020