Drosophila melanogaster

78 known processes

Dok (Dmel_CG2079)

Downstream of kinase

(Aliases: Dmel\CG2079,CG2079,l(1)G0331,Ddok)

Dok biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.373
establishment of localization in cell GO:0051649 402 0.358
dna metabolic process GO:0006259 227 0.254
endocytosis GO:0006897 310 0.249
axonogenesis GO:0007409 290 0.195
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.177
sensory organ morphogenesis GO:0090596 260 0.171
programmed cell death GO:0012501 257 0.170
Worm
small molecule metabolic process GO:0044281 305 0.161
compound eye photoreceptor cell differentiation GO:0001751 140 0.148
organophosphate metabolic process GO:0019637 195 0.142
cellular protein modification process GO:0006464 438 0.135
imaginal disc derived appendage development GO:0048737 399 0.133
protein modification process GO:0036211 438 0.122
positive regulation of wnt signaling pathway GO:0030177 25 0.120
photoreceptor cell differentiation GO:0046530 170 0.112
respiratory system development GO:0060541 213 0.098
camera type eye development GO:0043010 4 0.095
cellular catabolic process GO:0044248 372 0.089
positive regulation of gene expression GO:0010628 290 0.088
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.086
eye morphogenesis GO:0048592 260 0.082
photoreceptor cell fate commitment GO:0046552 41 0.078
phagocytosis GO:0006909 215 0.069
compound eye morphogenesis GO:0001745 249 0.067
appendage development GO:0048736 401 0.067
nucleotide catabolic process GO:0009166 109 0.067
eye development GO:0001654 323 0.065
response to organic substance GO:0010033 284 0.064
imaginal disc derived appendage morphogenesis GO:0035114 395 0.061
regulation of gtpase activity GO:0043087 44 0.059
cell death GO:0008219 279 0.057
Worm
eye photoreceptor cell differentiation GO:0001754 145 0.057
endomembrane system organization GO:0010256 119 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
open tracheal system development GO:0007424 204 0.056
proteoglycan biosynthetic process GO:0030166 10 0.055
guanosine containing compound metabolic process GO:1901068 74 0.055
actin cytoskeleton organization GO:0030036 206 0.055
head development GO:0060322 135 0.055
morphogenesis of a polarized epithelium GO:0001738 93 0.054
cellular ketone metabolic process GO:0042180 24 0.054
immune system process GO:0002376 347 0.052
positive regulation of molecular function GO:0044093 136 0.052
secretion by cell GO:0032940 101 0.052
post embryonic appendage morphogenesis GO:0035120 385 0.051
reproductive system development GO:0061458 74 0.050
macromolecular complex assembly GO:0065003 256 0.049
establishment of planar polarity GO:0001736 87 0.048
death GO:0016265 284 0.048
Worm
regulation of wnt signaling pathway GO:0030111 68 0.048
developmental programmed cell death GO:0010623 138 0.047
establishment of protein localization GO:0045184 163 0.047
nucleoside catabolic process GO:0009164 112 0.046
organelle localization GO:0051640 148 0.045
central nervous system development GO:0007417 201 0.045
single organism intracellular transport GO:1902582 207 0.044
cytoplasmic transport GO:0016482 130 0.043
organic substance catabolic process GO:1901575 308 0.043
transcription from rna polymerase ii promoter GO:0006366 368 0.042
purine nucleotide catabolic process GO:0006195 109 0.042
cellular response to extracellular stimulus GO:0031668 64 0.042
response to abiotic stimulus GO:0009628 341 0.041
protein localization GO:0008104 284 0.040
rho protein signal transduction GO:0007266 14 0.040
microtubule organizing center organization GO:0031023 168 0.040
catabolic process GO:0009056 409 0.039
heterocycle catabolic process GO:0046700 166 0.039
cellular protein localization GO:0034613 160 0.039
regulation of cellular ketone metabolic process GO:0010565 3 0.039
chromosome organization GO:0051276 360 0.038
response to oxygen containing compound GO:1901700 200 0.038
cell motility GO:0048870 251 0.038
secretion GO:0046903 109 0.038
gtp catabolic process GO:0006184 72 0.038
wing disc morphogenesis GO:0007472 344 0.037
ribose phosphate metabolic process GO:0019693 145 0.037
embryonic organ development GO:0048568 50 0.037
cellular nitrogen compound catabolic process GO:0044270 165 0.036
regulation of organelle organization GO:0033043 196 0.036
regulation of cytoskeleton organization GO:0051493 89 0.035
small gtpase mediated signal transduction GO:0007264 88 0.035
regulation of rho protein signal transduction GO:0035023 20 0.035
compound eye photoreceptor fate commitment GO:0001752 36 0.034
gland morphogenesis GO:0022612 145 0.034
wnt signaling pathway GO:0016055 98 0.034
regulation of ras gtpase activity GO:0032318 38 0.034
regulation of catalytic activity GO:0050790 185 0.034
homeostatic process GO:0042592 199 0.034
single organism catabolic process GO:0044712 228 0.034
dna replication GO:0006260 48 0.033
regulation of neurogenesis GO:0050767 158 0.033
regulation of cell death GO:0010941 173 0.033
developmental growth GO:0048589 280 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
photoreceptor cell development GO:0042461 96 0.032
protein transport GO:0015031 155 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
regulation of cell development GO:0060284 215 0.032
regulation of cellular catabolic process GO:0031329 157 0.032
intracellular transport GO:0046907 228 0.031
nucleoside phosphate catabolic process GO:1901292 110 0.031
epithelial cell development GO:0002064 274 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
response to gravity GO:0009629 26 0.031
actin filament organization GO:0007015 126 0.030
organic substance transport GO:0071702 257 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.030
single organism biosynthetic process GO:0044711 206 0.030
cellular macromolecule localization GO:0070727 220 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
nucleocytoplasmic transport GO:0006913 72 0.029
ubiquitin dependent protein catabolic process GO:0006511 78 0.029
gene silencing GO:0016458 138 0.028
apoptotic process GO:0006915 159 0.028
Worm
compound eye development GO:0048749 307 0.028
apoptotic cell clearance GO:0043277 14 0.028
proteolysis GO:0006508 192 0.028
dna repair GO:0006281 54 0.027
glycosyl compound catabolic process GO:1901658 112 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
cell cycle arrest GO:0007050 4 0.027
regulation of neuron differentiation GO:0045664 103 0.027
regulation of protein localization GO:0032880 76 0.027
regulation of rho gtpase activity GO:0032319 20 0.026
gtp metabolic process GO:0046039 72 0.026
organic acid metabolic process GO:0006082 103 0.026
salivary gland morphogenesis GO:0007435 145 0.026
positive regulation of hydrolase activity GO:0051345 78 0.026
digestive tract morphogenesis GO:0048546 127 0.026
macromolecule catabolic process GO:0009057 161 0.026
purine nucleoside catabolic process GO:0006152 112 0.025
regulation of molecular function GO:0065009 217 0.025
oxoacid metabolic process GO:0043436 103 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
neuron fate commitment GO:0048663 50 0.025
gland development GO:0048732 191 0.025
imaginal disc fusion GO:0046528 19 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
microtubule based movement GO:0007018 51 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
chromatin organization GO:0006325 207 0.024
appendage morphogenesis GO:0035107 397 0.023
chaeta development GO:0022416 97 0.023
regionalization GO:0003002 416 0.023
maintenance of location GO:0051235 73 0.023
cell proliferation GO:0008283 299 0.023
taxis GO:0042330 304 0.023
neuron projection guidance GO:0097485 241 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
cellular homeostasis GO:0019725 80 0.022
ameboidal type cell migration GO:0001667 151 0.022
tube development GO:0035295 244 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
notch signaling pathway GO:0007219 120 0.021
positive regulation of transport GO:0051050 92 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
male gamete generation GO:0048232 201 0.021
actin filament bundle organization GO:0061572 28 0.021
ras protein signal transduction GO:0007265 88 0.021
covalent chromatin modification GO:0016569 106 0.021
dorsal closure GO:0007391 79 0.021
positive regulation of nucleoside metabolic process GO:0045979 47 0.020
exocrine system development GO:0035272 162 0.020
innate immune response GO:0045087 144 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
meiotic cell cycle process GO:1903046 132 0.020
protein secretion GO:0009306 45 0.020
regulation of cellular localization GO:0060341 136 0.020
multi organism behavior GO:0051705 175 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
cellular protein catabolic process GO:0044257 83 0.020
connective tissue development GO:0061448 3 0.019
regulation of intracellular transport GO:0032386 64 0.019
chromosome segregation GO:0007059 157 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.019
eye photoreceptor cell development GO:0042462 81 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
growth GO:0040007 359 0.019
dna recombination GO:0006310 32 0.019
purine containing compound metabolic process GO:0072521 155 0.019
regulation of cell proliferation GO:0042127 163 0.019
nucleoside metabolic process GO:0009116 127 0.018
determination of adult lifespan GO:0008340 137 0.018
salivary gland development GO:0007431 162 0.018
antimicrobial humoral response GO:0019730 99 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
neurological system process GO:0050877 358 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
histone h4 k16 acetylation GO:0043984 4 0.017
embryonic morphogenesis GO:0048598 206 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
double strand break repair GO:0006302 26 0.017
cellular response to external stimulus GO:0071496 66 0.017
locomotory behavior GO:0007626 176 0.017
guanosine containing compound catabolic process GO:1901069 74 0.017
positive regulation of neuron differentiation GO:0045666 26 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
aminoglycan metabolic process GO:0006022 18 0.017
cell maturation GO:0048469 144 0.017
actin filament bundle assembly GO:0051017 26 0.017
regulation of response to stress GO:0080134 200 0.016
regulation of phospholipase activity GO:0010517 2 0.016
eye photoreceptor cell fate commitment GO:0042706 37 0.016
adult locomotory behavior GO:0008344 76 0.016
smoothened signaling pathway GO:0007224 49 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
body morphogenesis GO:0010171 2 0.016
bmp signaling pathway GO:0030509 27 0.016
regulation of hydrolase activity GO:0051336 97 0.016
developmental cell growth GO:0048588 52 0.016
mapk cascade GO:0000165 107 0.016
regulation of bmp signaling pathway GO:0030510 23 0.016
peptidyl lysine modification GO:0018205 57 0.016
cell division GO:0051301 248 0.016
intracellular signal transduction GO:0035556 300 0.016
protein catabolic process GO:0030163 101 0.016
lipid metabolic process GO:0006629 121 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
positive regulation of response to external stimulus GO:0032103 44 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
gene silencing by rna GO:0031047 57 0.015
nucleotide metabolic process GO:0009117 161 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
pigmentation GO:0043473 75 0.015
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
r3 r4 cell fate commitment GO:0007464 10 0.015
regulation of chromosome organization GO:0033044 64 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
response to extracellular stimulus GO:0009991 116 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
cellular response to organic substance GO:0071310 132 0.014
cell growth GO:0016049 108 0.014
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.014
signal transduction in response to dna damage GO:0042770 3 0.014
response to organic cyclic compound GO:0014070 89 0.014
positive regulation of jun kinase activity GO:0043507 4 0.014
centrosome duplication GO:0051298 121 0.014
phosphorylation GO:0016310 294 0.014
intracellular protein transport GO:0006886 104 0.014
chromatin modification GO:0016568 147 0.014
organophosphate catabolic process GO:0046434 112 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
telencephalon development GO:0021537 2 0.013
histone h4 acetylation GO:0043967 13 0.013
purine containing compound catabolic process GO:0072523 112 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
epithelial cell differentiation GO:0030855 322 0.013
actin filament based process GO:0030029 220 0.013
multi multicellular organism process GO:0044706 123 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
negative regulation of nervous system development GO:0051961 92 0.013
negative regulation of cell communication GO:0010648 223 0.013
protein complex biogenesis GO:0070271 201 0.013
regulation of protein metabolic process GO:0051246 256 0.013
dna integrity checkpoint GO:0031570 81 0.013
regulation of catabolic process GO:0009894 170 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
neuromuscular process GO:0050905 21 0.013
golgi organization GO:0007030 66 0.013
camera type eye morphogenesis GO:0048593 2 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
positive regulation of catabolic process GO:0009896 105 0.013
regulation of nucleotide catabolic process GO:0030811 48 0.013
protein phosphorylation GO:0006468 169 0.013
meiotic chromosome segregation GO:0045132 59 0.013
dna damage checkpoint GO:0000077 78 0.013
regulation of cell shape GO:0008360 113 0.013
regulation of cellular component size GO:0032535 98 0.013
organonitrogen compound catabolic process GO:1901565 128 0.012
immune response GO:0006955 246 0.012
negative regulation of developmental process GO:0051093 201 0.012
mitotic nuclear division GO:0007067 213 0.012
positive regulation of ras gtpase activity GO:0032320 36 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
negative regulation of phosphorus metabolic process GO:0010563 45 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
cellular response to decreased oxygen levels GO:0036294 30 0.012
cell cycle checkpoint GO:0000075 95 0.012
multicellular organismal homeostasis GO:0048871 41 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
amine metabolic process GO:0009308 12 0.012
muscle cell differentiation GO:0042692 103 0.012
autophagic cell death GO:0048102 83 0.012
molting cycle GO:0042303 56 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012
forebrain development GO:0030900 2 0.012
regulation of phosphorylation GO:0042325 147 0.012
mating behavior GO:0007617 106 0.012
nuclear division GO:0000280 332 0.012
brain development GO:0007420 120 0.012
centrosome organization GO:0051297 163 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.011
cardiovascular system development GO:0072358 82 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.011
chemosensory behavior GO:0007635 106 0.011
response to ionizing radiation GO:0010212 32 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
tissue morphogenesis GO:0048729 297 0.011
epithelial cell morphogenesis GO:0003382 25 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
nucleus localization GO:0051647 34 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
double strand break repair via homologous recombination GO:0000724 13 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
protein maturation GO:0051604 71 0.011
response to purine containing compound GO:0014074 12 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.011
protein localization to organelle GO:0033365 82 0.011
vesicle organization GO:0016050 44 0.011
regulation of immune system process GO:0002682 176 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
aromatic compound catabolic process GO:0019439 166 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
erbb signaling pathway GO:0038127 58 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
regulation of actin filament based process GO:0032970 42 0.010
negative regulation of cell death GO:0060548 81 0.010
positive regulation of cell development GO:0010720 61 0.010
multi organism reproductive behavior GO:0044705 121 0.010
regulation of anatomical structure size GO:0090066 163 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
regulation of chromatin modification GO:1903308 28 0.010
regulation of transferase activity GO:0051338 58 0.010

Dok disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018