Drosophila melanogaster

192 known processes

zip (Dmel_CG15792)

zipper

(Aliases: anon-WO0140519.37,Zip,Myo-II,Dronm-MII,Myo-II HC,nmMHC,zpr,nmy-2,l(2)02957,MHC,zip/MyoII,E(br),DmnmII,Dm nmII,MyoII,CG15792,Dmel\CG15792,Myo II,Mhc-c[1],DROMHC,myoII,Mhc-c,Myo,NMM)

zip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic morphogenesis GO:0048598 206 0.999
ovarian follicle cell migration GO:0007297 121 0.998
imaginal disc derived wing hair organization GO:0035317 45 0.998
post embryonic appendage morphogenesis GO:0035120 385 0.998
cell motility GO:0048870 251 0.998
border follicle cell migration GO:0007298 113 0.994
appendage morphogenesis GO:0035107 397 0.994
digestive system development GO:0055123 149 0.993
imaginal disc derived appendage morphogenesis GO:0035114 395 0.993
imaginal disc derived wing morphogenesis GO:0007476 337 0.993
actin filament based process GO:0030029 220 0.993
imaginal disc derived appendage development GO:0048737 399 0.991
cell migration GO:0016477 238 0.991
columnar cuboidal epithelial cell development GO:0002066 249 0.991
tissue migration GO:0090130 155 0.990
skin development GO:0043588 65 0.988
localization of cell GO:0051674 257 0.985
morphogenesis of an epithelium GO:0002009 276 0.980
dorsal closure GO:0007391 79 0.973
axonogenesis GO:0007409 290 0.970
Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.966
wing disc morphogenesis GO:0007472 344 0.965
epithelium migration GO:0090132 148 0.964
respiratory system development GO:0060541 213 0.957
actin cytoskeleton organization GO:0030036 206 0.955
hair cell differentiation GO:0035315 47 0.938
muscle cell development GO:0055001 50 0.934
epithelial cell migration GO:0010631 148 0.925
open tracheal system development GO:0007424 204 0.924
ameboidal type cell migration GO:0001667 151 0.923
epithelial cell differentiation GO:0030855 322 0.915
establishment of planar polarity GO:0001736 87 0.906
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.898
regulation of multicellular organismal development GO:2000026 414 0.884
Zebrafish Worm
regulation of tube architecture open tracheal system GO:0035152 68 0.877
striated muscle cell differentiation GO:0051146 90 0.861
tube morphogenesis GO:0035239 191 0.855
spermatid differentiation GO:0048515 114 0.841
oocyte differentiation GO:0009994 145 0.837
tube development GO:0035295 244 0.835
death GO:0016265 284 0.820
Worm
oocyte development GO:0048599 124 0.809
cellular protein localization GO:0034613 160 0.803
epithelial cell development GO:0002064 274 0.800
embryonic development via the syncytial blastoderm GO:0001700 148 0.794
oocyte axis specification GO:0007309 108 0.788
regulation of anatomical structure morphogenesis GO:0022603 242 0.787
Human Zebrafish Mouse Worm
actin filament organization GO:0007015 126 0.779
malpighian tubule morphogenesis GO:0007443 44 0.775
digestive tract morphogenesis GO:0048546 127 0.751
neuron projection guidance GO:0097485 241 0.723
Mouse
axon development GO:0061564 297 0.712
Mouse Worm
ovarian follicle cell development GO:0030707 248 0.702
tissue morphogenesis GO:0048729 297 0.685
appendage development GO:0048736 401 0.677
regulation of organelle organization GO:0033043 196 0.671
female germ line cyst formation GO:0048135 42 0.671
molting cycle GO:0042303 56 0.658
regulation of actin filament based process GO:0032970 42 0.657
purine ribonucleotide catabolic process GO:0009154 109 0.650
Human Mouse
apical junction assembly GO:0043297 32 0.649
circulatory system development GO:0072359 82 0.648
Human Mouse
epidermis development GO:0008544 65 0.646
heart development GO:0007507 82 0.645
Human Mouse
dna metabolic process GO:0006259 227 0.645
muscle cell differentiation GO:0042692 103 0.644
renal system development GO:0072001 72 0.639
embryonic hemopoiesis GO:0035162 26 0.631
germarium derived egg chamber formation GO:0007293 101 0.631
cellular component assembly involved in morphogenesis GO:0010927 151 0.630
sensory organ morphogenesis GO:0090596 260 0.624
positive regulation of cellular component organization GO:0051130 156 0.608
endocytosis GO:0006897 310 0.605
Worm
central nervous system development GO:0007417 201 0.588
Mouse
germ line cyst formation GO:0048134 44 0.578
hindgut morphogenesis GO:0007442 58 0.571
pigmentation GO:0043473 75 0.566
small molecule metabolic process GO:0044281 305 0.565
Human Mouse
nucleotide metabolic process GO:0009117 161 0.560
Human Mouse
actin filament bundle organization GO:0061572 28 0.546
embryo development ending in birth or egg hatching GO:0009792 152 0.544
eye development GO:0001654 323 0.542
Mouse
eye morphogenesis GO:0048592 260 0.539
germarium derived female germ line cyst formation GO:0030727 42 0.536
compound eye development GO:0048749 307 0.522
establishment of tissue polarity GO:0007164 87 0.518
multi organism behavior GO:0051705 175 0.512
cell junction assembly GO:0034329 42 0.507
regulation of cytoskeleton organization GO:0051493 89 0.507
organophosphate metabolic process GO:0019637 195 0.495
Human Mouse
maintenance of protein location GO:0045185 28 0.490
epithelial tube morphogenesis GO:0060562 88 0.489
epidermal cell differentiation GO:0009913 51 0.485
glycosyl compound metabolic process GO:1901657 127 0.482
Human Mouse
digestive tract development GO:0048565 149 0.477
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.477
intracellular transport GO:0046907 228 0.470
purine nucleoside triphosphate metabolic process GO:0009144 119 0.466
Human Mouse
oocyte construction GO:0007308 112 0.456
regulation of rho protein signal transduction GO:0035023 20 0.454
spermatogenesis GO:0007283 200 0.451
regulation of cell adhesion GO:0030155 27 0.444
purine containing compound catabolic process GO:0072523 112 0.431
Human Mouse
embryonic organ development GO:0048568 50 0.428
regulation of cell death GO:0010941 173 0.427
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.421
macromolecular complex assembly GO:0065003 256 0.410
cell junction organization GO:0034330 57 0.409
non sensory hair organization GO:0035316 47 0.408
renal tubule development GO:0061326 64 0.403
myofibril assembly GO:0030239 36 0.403
programmed cell death GO:0012501 257 0.402
Worm
actin polymerization or depolymerization GO:0008154 31 0.401
organonitrogen compound metabolic process GO:1901564 318 0.396
Human Mouse
oocyte microtubule cytoskeleton organization GO:0016325 35 0.392
regulation of actin filament polymerization GO:0030833 25 0.385
muscle structure development GO:0061061 224 0.381
regulation of actin cytoskeleton organization GO:0032956 42 0.375
multicellular organismal reproductive behavior GO:0033057 110 0.375
cytokinesis GO:0000910 90 0.373
regulation of cellular component biogenesis GO:0044087 201 0.372
spermatid development GO:0007286 98 0.370
anterior posterior pattern specification GO:0009952 136 0.365
Worm
regulation of actin polymerization or depolymerization GO:0008064 27 0.350
striated muscle cell development GO:0055002 50 0.344
chromosome organization GO:0051276 360 0.343
purine nucleoside metabolic process GO:0042278 127 0.332
Human Mouse
regulation of actin filament length GO:0030832 27 0.327
cell proliferation GO:0008283 299 0.318
Mouse
apoptotic process GO:0006915 159 0.293
Worm
positive regulation of macromolecule metabolic process GO:0010604 405 0.292
nucleoside phosphate metabolic process GO:0006753 162 0.291
Human Mouse
actin filament bundle assembly GO:0051017 26 0.286
regulation of organ morphogenesis GO:2000027 78 0.275
Zebrafish
regulation of nervous system development GO:0051960 248 0.273
dorsal closure amnioserosa morphology change GO:0046664 7 0.272
regulation of cell morphogenesis GO:0022604 163 0.268
Human Mouse Worm
eggshell formation GO:0030703 105 0.259
exocrine system development GO:0035272 162 0.257
genitalia morphogenesis GO:0035112 16 0.255
eye photoreceptor cell differentiation GO:0001754 145 0.248
regulation of protein polymerization GO:0032271 28 0.246
purine containing compound metabolic process GO:0072521 155 0.243
Human Mouse
regulation of protein metabolic process GO:0051246 256 0.243
heart morphogenesis GO:0003007 32 0.236
extracellular structure organization GO:0043062 46 0.232
Human
positive regulation of cellular component biogenesis GO:0044089 80 0.228
establishment of protein localization GO:0045184 163 0.227
Human
cellular catabolic process GO:0044248 372 0.227
Human Mouse
autophagy GO:0006914 108 0.223
gliogenesis GO:0042063 80 0.218
ribonucleoside catabolic process GO:0042454 112 0.217
Human Mouse
neuron recognition GO:0008038 101 0.214
Worm
dendrite morphogenesis GO:0048813 199 0.213
dendrite development GO:0016358 204 0.213
male gamete generation GO:0048232 201 0.213
nucleoside triphosphate catabolic process GO:0009143 108 0.211
Human Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.209
Human Mouse
ribonucleotide metabolic process GO:0009259 145 0.209
Human Mouse
regulation of cell shape GO:0008360 113 0.207
Human Mouse Worm
cellular protein modification process GO:0006464 438 0.205
carbohydrate derivative metabolic process GO:1901135 217 0.204
Human Mouse
catabolic process GO:0009056 409 0.202
Human Mouse
cell death GO:0008219 279 0.200
Worm
intracellular signal transduction GO:0035556 300 0.199
negative regulation of gene expression GO:0010629 387 0.194
protein transport GO:0015031 155 0.194
Human
ribonucleotide catabolic process GO:0009261 109 0.190
Human Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.187
Human Mouse
mating GO:0007618 120 0.184
imaginal disc derived wing hair site selection GO:0035320 4 0.182
purine ribonucleoside catabolic process GO:0046130 112 0.182
Human Mouse
body morphogenesis GO:0010171 2 0.180
Worm
maintenance of location GO:0051235 73 0.179
regulation of cellular protein metabolic process GO:0032268 243 0.178
regulation of wnt signaling pathway GO:0030111 68 0.177
carbohydrate derivative catabolic process GO:1901136 118 0.175
Human Mouse
multi organism reproductive behavior GO:0044705 121 0.175
reproductive behavior GO:0019098 122 0.169
positive regulation of developmental process GO:0051094 143 0.169
heterocycle catabolic process GO:0046700 166 0.167
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.163
Human Mouse
negative regulation of cell communication GO:0010648 223 0.161
organonitrogen compound catabolic process GO:1901565 128 0.158
Human Mouse
purine nucleotide metabolic process GO:0006163 146 0.158
Human Mouse
axon guidance GO:0007411 233 0.158
Mouse
glial cell migration GO:0008347 31 0.158
cellular response to metal ion GO:0071248 6 0.157
actomyosin structure organization GO:0031032 56 0.155
malpighian tubule development GO:0072002 64 0.154
cell adhesion GO:0007155 136 0.154
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.154
hemocyte migration GO:0035099 19 0.152
maintenance of protein location in cell GO:0032507 26 0.150
regulation of filopodium assembly GO:0051489 24 0.150
ribonucleoside triphosphate catabolic process GO:0009203 108 0.150
Human Mouse
dorsal appendage formation GO:0046843 47 0.148
cell projection assembly GO:0030031 94 0.147
Mouse
protein modification process GO:0036211 438 0.147
actin cytoskeleton reorganization GO:0031532 22 0.147
Human
cellularization GO:0007349 90 0.147
ribonucleoside metabolic process GO:0009119 127 0.144
Human Mouse
regulation of embryonic development GO:0045995 68 0.143
Worm
salivary gland development GO:0007431 162 0.143
negative regulation of programmed cell death GO:0043069 72 0.141
endomembrane system organization GO:0010256 119 0.141
Mouse
establishment of ommatidial planar polarity GO:0042067 49 0.140
small gtpase mediated signal transduction GO:0007264 88 0.139
purine nucleotide catabolic process GO:0006195 109 0.138
Human Mouse
regulation of cell differentiation GO:0045595 302 0.136
Zebrafish
molting cycle chitin based cuticle GO:0007591 56 0.136
genitalia development GO:0048806 26 0.136
Worm
positive regulation of gene expression GO:0010628 290 0.135
regulation of transport GO:0051049 181 0.135
cardiovascular system development GO:0072358 82 0.134
Human Mouse
establishment of localization in cell GO:0051649 402 0.133
Mouse
regulation of catabolic process GO:0009894 170 0.132
protein complex assembly GO:0006461 200 0.132
regionalization GO:0003002 416 0.128
axonal fasciculation GO:0007413 12 0.127
Worm
regulation of protein complex assembly GO:0043254 42 0.127
regulation of molecular function GO:0065009 217 0.124
hindgut development GO:0061525 58 0.120
hematopoietic or lymphoid organ development GO:0048534 57 0.114
Human
pole plasm mrna localization GO:0019094 49 0.113
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.113
axis specification GO:0009798 167 0.110
nucleotide catabolic process GO:0009166 109 0.105
Human Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.105
Human Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.104
morphogenesis of a polarized epithelium GO:0001738 93 0.101
Zebrafish
protein localization GO:0008104 284 0.101
dorsal trunk growth open tracheal system GO:0035001 7 0.100
membrane organization GO:0061024 112 0.099
Mouse
ribose phosphate metabolic process GO:0019693 145 0.099
Human Mouse
sex differentiation GO:0007548 81 0.098
Worm
organelle assembly GO:0070925 198 0.097
cardiocyte differentiation GO:0035051 29 0.096
Human Mouse
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.096
chorion containing eggshell formation GO:0007304 105 0.095
somatic stem cell division GO:0048103 37 0.092
purine nucleoside triphosphate catabolic process GO:0009146 108 0.088
Human Mouse
regulation of hydrolase activity GO:0051336 97 0.088
regulation of neuroblast proliferation GO:1902692 34 0.088
guanosine containing compound catabolic process GO:1901069 74 0.086
meiotic cell cycle process GO:1903046 132 0.086
Mouse
phagocytosis GO:0006909 215 0.086
nucleobase containing small molecule metabolic process GO:0055086 174 0.086
Human Mouse
homeostatic process GO:0042592 199 0.085
positive regulation of cell adhesion GO:0045785 10 0.085
organic substance catabolic process GO:1901575 308 0.085
Human Mouse
cellular macromolecular complex assembly GO:0034622 153 0.083
oviposition GO:0018991 19 0.082
regulation of response to stress GO:0080134 200 0.079
response to abiotic stimulus GO:0009628 341 0.079
head development GO:0060322 135 0.079
Mouse
endoderm formation GO:0001706 3 0.078
dorsal closure elongation of leading edge cells GO:0007394 10 0.077
rhabdomere development GO:0042052 38 0.076
pole plasm assembly GO:0007315 61 0.076
cell type specific apoptotic process GO:0097285 38 0.076
cellular macromolecule localization GO:0070727 220 0.075
intracellular protein transport GO:0006886 104 0.074
camera type eye development GO:0043010 4 0.074
Mouse
receptor mediated endocytosis GO:0006898 21 0.074
Worm
regulation of intracellular signal transduction GO:1902531 236 0.074
regulation of dendrite morphogenesis GO:0048814 28 0.074
oocyte anterior posterior axis specification GO:0007314 72 0.072
cellular protein complex assembly GO:0043623 71 0.072
cellular nitrogen compound catabolic process GO:0044270 165 0.071
Human Mouse
positive regulation of molecular function GO:0044093 136 0.071
establishment of proximal distal cell polarity GO:0022606 4 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
Human Mouse
positive regulation of filopodium assembly GO:0051491 15 0.070
wnt signaling pathway GO:0016055 98 0.070
actin filament polymerization GO:0030041 27 0.069
neuroblast proliferation GO:0007405 74 0.067
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.066
reproductive system development GO:0061458 74 0.066
Worm
cellular response to dna damage stimulus GO:0006974 223 0.066
organelle fission GO:0048285 340 0.066
regulation of tube diameter GO:0035296 14 0.065
plasma membrane organization GO:0007009 26 0.065
Mouse
hemopoiesis GO:0030097 46 0.065
Human
pericardium morphogenesis GO:0003344 2 0.064
cell cell junction assembly GO:0007043 38 0.064
muscle attachment GO:0016203 36 0.063
regulation of neurogenesis GO:0050767 158 0.063
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.062
nephron morphogenesis GO:0072028 3 0.062
regulation of stem cell proliferation GO:0072091 40 0.062
pole plasm oskar mrna localization GO:0045451 46 0.062
photoreceptor cell development GO:0042461 96 0.062
sarcomere organization GO:0045214 26 0.062
immune system development GO:0002520 57 0.061
Human
cuticle development GO:0042335 86 0.059
single organism behavior GO:0044708 391 0.059
Human
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.058
protein localization to plasma membrane GO:0072659 13 0.058
negative regulation of signal transduction GO:0009968 206 0.057
regulation of cell proliferation GO:0042127 163 0.057
response to wounding GO:0009611 94 0.057
cell substrate adhesion GO:0031589 10 0.057
aromatic compound catabolic process GO:0019439 166 0.056
Human Mouse
regulation of cell development GO:0060284 215 0.055
proteolysis GO:0006508 192 0.055
Human
regulation of developmental pigmentation GO:0048070 24 0.055
eggshell chorion assembly GO:0007306 66 0.055
organic substance transport GO:0071702 257 0.054
Human
vesicle mediated transport GO:0016192 381 0.054
Mouse Worm
negative regulation of apoptotic process GO:0043066 63 0.053
segmentation GO:0035282 207 0.052
cell cell junction organization GO:0045216 55 0.051
organophosphate catabolic process GO:0046434 112 0.050
Human Mouse
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.050
renal tubule morphogenesis GO:0061333 44 0.049
cytoskeleton dependent cytokinesis GO:0061640 81 0.049
nephron development GO:0072006 3 0.048
developmental maturation GO:0021700 172 0.048
biological adhesion GO:0022610 138 0.048
Human Mouse
modification dependent protein catabolic process GO:0019941 78 0.048
single organism intracellular transport GO:1902582 207 0.048
positive regulation of signaling GO:0023056 243 0.047
single organism membrane organization GO:0044802 93 0.047
Mouse
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.047
chitin based cuticle development GO:0040003 49 0.047
positive regulation of rna metabolic process GO:0051254 271 0.047
peripheral nervous system development GO:0007422 52 0.047
positive regulation of actin filament polymerization GO:0030838 11 0.047
protein phosphorylation GO:0006468 169 0.046
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.046
protein localization to organelle GO:0033365 82 0.045
compound eye morphogenesis GO:0001745 249 0.045
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.045
urogenital system development GO:0001655 72 0.045
spiracle morphogenesis open tracheal system GO:0035277 22 0.045
cortical actin cytoskeleton organization GO:0030866 24 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.044
endodermal cell differentiation GO:0035987 3 0.044
regulation of neuron differentiation GO:0045664 103 0.043
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
positive regulation of signal transduction GO:0009967 223 0.042
response to nutrient levels GO:0031667 114 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.042
Human Mouse
regulation of protein stability GO:0031647 43 0.042
regulation of apoptotic process GO:0042981 130 0.042
positive regulation of protein complex assembly GO:0031334 22 0.041
mesoderm development GO:0007498 78 0.041
rna localization GO:0006403 115 0.041
lipid storage GO:0019915 38 0.041
single organism cellular localization GO:1902580 180 0.041
Mouse
stem cell maintenance GO:0019827 67 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
embryonic pattern specification GO:0009880 174 0.040
single organism catabolic process GO:0044712 228 0.040
Human Mouse
epithelial cell cell adhesion GO:0090136 6 0.040
unidimensional cell growth GO:0009826 15 0.040
response to starvation GO:0042594 97 0.039
aging GO:0007568 143 0.038
regulation of cell migration GO:0030334 22 0.038
regulation of small gtpase mediated signal transduction GO:0051056 93 0.038
positive regulation of programmed cell death GO:0043068 62 0.038
regulation of localization GO:0032879 275 0.038
regulation of mitotic cell cycle GO:0007346 190 0.037
ras protein signal transduction GO:0007265 88 0.037
pole plasm rna localization GO:0007316 52 0.037
wound healing GO:0042060 75 0.036
negative regulation of response to stimulus GO:0048585 258 0.036
embryonic hindgut morphogenesis GO:0048619 48 0.035
apoptotic cell clearance GO:0043277 14 0.035
regulation of tube size GO:0035150 46 0.035
single organismal cell cell adhesion GO:0016337 45 0.035
Human Mouse
negative regulation of cellular catabolic process GO:0031330 34 0.034
regulation of ras protein signal transduction GO:0046578 93 0.034
head involution GO:0008258 35 0.034
positive regulation of rna biosynthetic process GO:1902680 266 0.034
phenol containing compound metabolic process GO:0018958 57 0.034
negative regulation of signaling GO:0023057 219 0.033
regulation of programmed cell death GO:0043067 152 0.033
tripartite regional subdivision GO:0007351 103 0.032
cell competition in a multicellular organism GO:0035212 10 0.032
ommatidial rotation GO:0016318 20 0.032
regulation of catalytic activity GO:0050790 185 0.032
spindle organization GO:0007051 253 0.031
Mouse
amine metabolic process GO:0009308 12 0.031
photoreceptor cell differentiation GO:0046530 170 0.030
eye photoreceptor cell development GO:0042462 81 0.030
developmental pigmentation GO:0048066 68 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
salivary gland morphogenesis GO:0007435 145 0.030
mapk cascade GO:0000165 107 0.030
negative regulation of cell death GO:0060548 81 0.029
regulation of cytokinesis GO:0032465 3 0.029
taxis GO:0042330 304 0.029
Mouse
response to light stimulus GO:0009416 124 0.029
regulation of synapse structure and activity GO:0050803 128 0.029
meiotic cytokinesis GO:0033206 33 0.029
dorsal ventral pattern formation GO:0009953 133 0.028
canonical wnt signaling pathway GO:0060070 21 0.028
reproductive structure development GO:0048608 74 0.028
Worm
cell growth GO:0016049 108 0.028
branching morphogenesis of an epithelial tube GO:0048754 45 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
filopodium assembly GO:0046847 33 0.027
immune response GO:0006955 246 0.027
purine nucleoside catabolic process GO:0006152 112 0.027
Human Mouse
regulation of cell substrate adhesion GO:0010810 2 0.027
positive regulation of apoptotic process GO:0043065 47 0.026
gtp metabolic process GO:0046039 72 0.026
regulation of malpighian tubule diameter GO:0035297 3 0.026
nucleobase containing compound catabolic process GO:0034655 165 0.026
Human Mouse
smoothened signaling pathway GO:0007224 49 0.026
enzyme linked receptor protein signaling pathway GO:0007167 179 0.026
negative regulation of cell differentiation GO:0045596 143 0.025
guanosine containing compound metabolic process GO:1901068 74 0.025
specification of symmetry GO:0009799 13 0.025
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.025
positive regulation of protein polymerization GO:0032273 14 0.025
positive regulation of catalytic activity GO:0043085 118 0.025
skeletal muscle organ development GO:0060538 48 0.024
Human
motor neuron axon guidance GO:0008045 58 0.024
establishment of protein localization to organelle GO:0072594 62 0.024
glial cell differentiation GO:0010001 35 0.024
multi multicellular organism process GO:0044706 123 0.023
positive regulation of cell motility GO:2000147 3 0.023
positive regulation of protein localization to plasma membrane GO:1903078 3 0.023
mitotic spindle organization GO:0007052 220 0.023
cell matrix adhesion GO:0007160 6 0.023
formation of primary germ layer GO:0001704 24 0.023
regulation of wound healing GO:0061041 13 0.023
synapse assembly GO:0007416 143 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
induction of programmed cell death by ecdysone GO:0035078 12 0.022
regulation of anatomical structure size GO:0090066 163 0.022
neuroblast division GO:0055057 35 0.022
regulation of viral genome replication GO:0045069 4 0.022
lipid localization GO:0010876 54 0.022
sensory perception GO:0007600 196 0.022
Human
larval development GO:0002164 104 0.021
Worm
meiotic cell cycle GO:0051321 171 0.021
Mouse
anterior posterior axis specification embryo GO:0008595 103 0.021
positive regulation of cell death GO:0010942 69 0.021
negative regulation of developmental process GO:0051093 201 0.021
regulation of protein localization GO:0032880 76 0.021
hindbrain development GO:0030902 2 0.021
Mouse
meiotic nuclear envelope disassembly GO:0051078 2 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
blastoderm segmentation GO:0007350 159 0.020
negative regulation of protein processing GO:0010955 31 0.020
cellular component disassembly GO:0022411 46 0.020
compound eye photoreceptor development GO:0042051 78 0.020
phosphorylation GO:0016310 294 0.020
brain development GO:0007420 120 0.020
Mouse
cellular amine metabolic process GO:0044106 12 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
cell division GO:0051301 248 0.020
pericardium development GO:0060039 2 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.019
r3 r4 cell fate commitment GO:0007464 10 0.019
skeletal muscle tissue development GO:0007519 13 0.019
Human
dna repair GO:0006281 54 0.019
morphogenesis of a branching structure GO:0001763 45 0.019
mitotic nuclear division GO:0007067 213 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
Human Mouse
negative regulation of proteolysis GO:0045861 31 0.019
regulation of smoothened signaling pathway GO:0008589 28 0.019
chemotaxis GO:0006935 249 0.019
Mouse
regulation of epithelial cell differentiation GO:0030856 4 0.019
Zebrafish
regulation of epithelial cell proliferation GO:0050678 4 0.019
oocyte morphogenesis GO:0048601 3 0.019
positive regulation of chromatin silencing at telomere GO:0031940 2 0.018
spinal cord development GO:0021510 1 0.018
morphogenesis of an epithelial bud GO:0060572 3 0.018
regulation of protein catabolic process GO:0042176 55 0.018
imaginal disc derived wing hair outgrowth GO:0035318 1 0.018
embryonic heart tube development GO:0035050 22 0.018
regulation of cell projection assembly GO:0060491 30 0.018
establishment of neuroblast polarity GO:0045200 2 0.018
positive regulation of cell proliferation GO:0008284 47 0.018
muscle organ development GO:0007517 127 0.018
Human
nephron epithelium morphogenesis GO:0072088 3 0.018
negative regulation of protein metabolic process GO:0051248 85 0.017
cardioblast cell fate specification GO:0042685 9 0.017
positive regulation of cell migration GO:0030335 2 0.017
lamellipodium assembly GO:0030032 21 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
Mouse

zip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.295
Human
familial meningioma DOID:4586 0 0.040
nervous system cancer DOID:3093 0 0.040
central nervous system cancer DOID:3620 0 0.040
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.040
meningioma DOID:3565 0 0.040
auditory system disease DOID:2742 0 0.033
Human
nonsyndromic deafness DOID:0050563 0 0.033
Human
sensory system disease DOID:0050155 0 0.033
Human
nervous system disease DOID:863 0 0.033
Human