Drosophila melanogaster

249 known processes

Ark (Dmel_CG6829)

Apaf-1-related-killer

(Aliases: apaf-1,dark/dapaf-1/hac-1,hac-1,Dark/Apaf-I,dApaf-1,DARK,arc,dApaf-1/DARK/HAC-1,ark,Dark/Hac-1/dApaf1,CG6829,Apaf1,Dark/Dapaf-1/HAC1,dark/hac-1/dapaf-1,Dapaf-1/HAC-1,dapaf,Hac1,dAPAF-1,Dark,Dmel\CG6829,D-Apaf-1,apaf1,dApaf1,anon-53Fa,Dapaf-1,Dark/Hac-1/dApaf-1,Hac-1/Dark,T1,dark,Apaf-1,dapaf-1S,Hac-1,hac1,dapaf-1,dArk,APAF1,ARK,dapaf-1L)

Ark biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
melanin metabolic process GO:0006582 47 0.293
immune effector process GO:0002252 98 0.223
eye development GO:0001654 323 0.197
positive regulation of endopeptidase activity GO:0010950 26 0.191
regulation of intracellular signal transduction GO:1902531 236 0.171
catabolic process GO:0009056 409 0.153
response to bacterium GO:0009617 198 0.150
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.145
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.143
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.135
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.132
sensory organ morphogenesis GO:0090596 260 0.131
gland morphogenesis GO:0022612 145 0.130
spermatid development GO:0007286 98 0.127
eye morphogenesis GO:0048592 260 0.126
regulation of anatomical structure morphogenesis GO:0022603 242 0.126
nuclear division GO:0000280 332 0.125
immune response GO:0006955 246 0.125
compound eye development GO:0048749 307 0.125
compound eye morphogenesis GO:0001745 249 0.122
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.118
defense response GO:0006952 300 0.118
cellular catabolic process GO:0044248 372 0.116
spermatid differentiation GO:0048515 114 0.114
positive regulation of cellular biosynthetic process GO:0031328 316 0.112
zymogen activation GO:0031638 20 0.112
execution phase of apoptosis GO:0097194 7 0.110
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.110
positive regulation of peptidase activity GO:0010952 29 0.110
regulation of cellular catabolic process GO:0031329 157 0.108
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.107
male gamete generation GO:0048232 201 0.107
response to abiotic stimulus GO:0009628 341 0.107
proteolysis GO:0006508 192 0.106
defense response to other organism GO:0098542 225 0.104
regulation of catabolic process GO:0009894 170 0.104
Mouse
single organism catabolic process GO:0044712 228 0.104
central nervous system development GO:0007417 201 0.103
cellular amide metabolic process GO:0043603 80 0.102
response to biotic stimulus GO:0009607 294 0.101
intracellular signal transduction GO:0035556 300 0.101
positive regulation of signal transduction GO:0009967 223 0.100
Mouse
positive regulation of proteolysis GO:0045862 52 0.100
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.098
embryonic morphogenesis GO:0048598 206 0.097
Mouse
phenol containing compound metabolic process GO:0018958 57 0.096
salivary gland development GO:0007431 162 0.095
hemocyte differentiation GO:0042386 38 0.092
positive regulation of apoptotic signaling pathway GO:2001235 4 0.092
Mouse
tissue death GO:0016271 102 0.090
gland development GO:0048732 191 0.087
spermatogenesis GO:0007283 200 0.087
response to external biotic stimulus GO:0043207 293 0.086
protein complex biogenesis GO:0070271 201 0.085
organonitrogen compound metabolic process GO:1901564 318 0.085
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.085
organelle fission GO:0048285 340 0.085
phagocytosis GO:0006909 215 0.084
histolysis GO:0007559 102 0.083
exocrine system development GO:0035272 162 0.082
response to other organism GO:0051707 293 0.081
cell death GO:0008219 279 0.081
meiotic cell cycle GO:0051321 171 0.078
organic substance transport GO:0071702 257 0.077
ovarian follicle cell development GO:0030707 248 0.077
macromolecular complex assembly GO:0065003 256 0.077
salivary gland morphogenesis GO:0007435 145 0.076
regulation of response to biotic stimulus GO:0002831 63 0.076
programmed cell death GO:0012501 257 0.075
melanization defense response GO:0035006 45 0.074
humoral immune response GO:0006959 117 0.072
regulation of production of molecular mediator of immune response GO:0002700 44 0.070
developmental programmed cell death GO:0010623 138 0.069
amide biosynthetic process GO:0043604 42 0.069
protein complex assembly GO:0006461 200 0.069
positive regulation of nucleic acid templated transcription GO:1903508 266 0.069
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.069
regulation of antimicrobial peptide production GO:0002784 44 0.068
positive regulation of signaling GO:0023056 243 0.067
Mouse
protein localization GO:0008104 284 0.066
embryo development ending in birth or egg hatching GO:0009792 152 0.066
Mouse
ovarian follicle cell migration GO:0007297 121 0.066
organic substance catabolic process GO:1901575 308 0.064
death GO:0016265 284 0.064
peptide metabolic process GO:0006518 80 0.063
positive regulation of response to extracellular stimulus GO:0032106 8 0.063
regulation of peptidase activity GO:0052547 39 0.062
sperm individualization GO:0007291 48 0.062
regulation of humoral immune response GO:0002920 51 0.062
regulation of defense response GO:0031347 102 0.062
secondary metabolic process GO:0019748 75 0.061
positive regulation of biosynthetic process GO:0009891 316 0.061
columnar cuboidal epithelial cell development GO:0002066 249 0.060
regulation of cell cycle g1 s phase transition GO:1902806 23 0.060
establishment of localization in cell GO:0051649 402 0.060
mitotic dna integrity checkpoint GO:0044774 75 0.060
antibacterial humoral response GO:0019731 44 0.060
positive regulation of catabolic process GO:0009896 105 0.059
regulation of molecular function GO:0065009 217 0.059
cellularization GO:0007349 90 0.058
endocytosis GO:0006897 310 0.058
negative regulation of cell communication GO:0010648 223 0.058
apoptotic process GO:0006915 159 0.057
dendrite development GO:0016358 204 0.057
cell migration GO:0016477 238 0.056
positive regulation of response to stimulus GO:0048584 323 0.056
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.055
negative regulation of cell cycle phase transition GO:1901988 103 0.054
response to radiation GO:0009314 155 0.054
embryonic development via the syncytial blastoderm GO:0001700 148 0.053
regulation of innate immune response GO:0045088 71 0.053
immune system process GO:0002376 347 0.053
regulation of antimicrobial humoral response GO:0002759 50 0.052
defense response to bacterium GO:0042742 178 0.052
cell proliferation GO:0008283 299 0.052
regulation of proteolysis GO:0030162 87 0.052
response to lipopolysaccharide GO:0032496 4 0.052
positive regulation of hydrolase activity GO:0051345 78 0.051
cell motility GO:0048870 251 0.051
antimicrobial peptide biosynthetic process GO:0002777 38 0.050
localization of cell GO:0051674 257 0.050
vesicle mediated transport GO:0016192 381 0.050
pigment metabolic process GO:0042440 84 0.049
regulation of mitotic cell cycle phase transition GO:1901990 130 0.048
positive regulation of programmed cell death GO:0043068 62 0.048
production of molecular mediator of immune response GO:0002440 46 0.048
synaptic transmission GO:0007268 288 0.048
protein secretion GO:0009306 45 0.048
antimicrobial peptide production GO:0002775 46 0.047
imaginal disc derived appendage development GO:0048737 399 0.047
epithelial cell differentiation GO:0030855 322 0.047
regulation of response to stress GO:0080134 200 0.047
positive regulation of transcription dna templated GO:0045893 266 0.047
positive regulation of cell communication GO:0010647 250 0.047
Mouse
macromolecule catabolic process GO:0009057 161 0.047
Mouse
autophagy GO:0006914 108 0.046
protein catabolic process GO:0030163 101 0.046
positive regulation of autophagy GO:0010508 21 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.045
protein ubiquitination GO:0016567 70 0.045
secretion by cell GO:0032940 101 0.045
positive regulation of cell death GO:0010942 69 0.045
negative regulation of signaling GO:0023057 219 0.044
regulation of organ morphogenesis GO:2000027 78 0.044
defense response to virus GO:0051607 23 0.044
imaginal disc derived appendage morphogenesis GO:0035114 395 0.044
appendage morphogenesis GO:0035107 397 0.044
spindle organization GO:0007051 253 0.043
epithelial cell development GO:0002064 274 0.043
neuron remodeling GO:0016322 29 0.043
positive regulation of gene expression GO:0010628 290 0.042
cellular response to dna damage stimulus GO:0006974 223 0.040
determination of adult lifespan GO:0008340 137 0.040
cell division GO:0051301 248 0.039
regulation of protein metabolic process GO:0051246 256 0.039
regulation of apoptotic process GO:0042981 130 0.039
multicellular organismal aging GO:0010259 140 0.038
organonitrogen compound biosynthetic process GO:1901566 117 0.038
establishment of protein localization GO:0045184 163 0.038
defense response to gram negative bacterium GO:0050829 94 0.038
regulation of protein transport GO:0051223 57 0.038
lateral inhibition GO:0046331 206 0.038
negative regulation of mitotic cell cycle GO:0045930 109 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
regulation of organelle organization GO:0033043 196 0.037
salivary gland histolysis GO:0035070 88 0.037
appendage development GO:0048736 401 0.036
nucleoside metabolic process GO:0009116 127 0.036
regulation of cell cycle GO:0051726 291 0.036
retinal cell programmed cell death GO:0046666 25 0.036
regulation of localization GO:0032879 275 0.036
regulation of catalytic activity GO:0050790 185 0.036
antimicrobial humoral response GO:0019730 99 0.036
compound eye retinal cell programmed cell death GO:0046667 23 0.036
salivary gland cell autophagic cell death GO:0035071 83 0.035
regulation of transport GO:0051049 181 0.034
regulation of defense response to virus GO:0050688 14 0.034
nurse cell apoptotic process GO:0045476 17 0.034
negative regulation of gene expression GO:0010629 387 0.034
autophagic cell death GO:0048102 83 0.034
positive regulation of immune response GO:0050778 63 0.034
ribonucleoside metabolic process GO:0009119 127 0.034
peptide biosynthetic process GO:0043043 42 0.034
response to ionizing radiation GO:0010212 32 0.033
signal transduction in response to dna damage GO:0042770 3 0.033
positive regulation of multicellular organismal process GO:0051240 143 0.033
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
regulation of cellular amide metabolic process GO:0034248 39 0.033
eggshell formation GO:0030703 105 0.033
response to organic cyclic compound GO:0014070 89 0.032
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.032
single organism behavior GO:0044708 391 0.032
regulation of synaptic transmission GO:0050804 69 0.032
regulation of defense response to bacterium GO:1900424 30 0.032
regulation of immune response GO:0050776 118 0.032
protein k48 linked ubiquitination GO:0070936 3 0.032
organic hydroxy compound metabolic process GO:1901615 83 0.032
protein modification by small protein conjugation or removal GO:0070647 106 0.032
single organism cellular localization GO:1902580 180 0.032
nitrogen compound transport GO:0071705 85 0.032
meiotic nuclear division GO:0007126 151 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
positive regulation of macroautophagy GO:0016239 8 0.031
positive regulation of molecular function GO:0044093 136 0.031
protein modification process GO:0036211 438 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
protein transport GO:0015031 155 0.031
aromatic compound catabolic process GO:0019439 166 0.031
Mouse
cell type specific apoptotic process GO:0097285 38 0.031
response to oxygen containing compound GO:1901700 200 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.031
positive regulation of defense response to bacterium GO:1900426 23 0.030
cellular response to extracellular stimulus GO:0031668 64 0.030
regulation of response to extracellular stimulus GO:0032104 18 0.030
ribonucleotide metabolic process GO:0009259 145 0.030
regulation of endopeptidase activity GO:0052548 36 0.030
positive regulation of defense response GO:0031349 59 0.030
response to extracellular stimulus GO:0009991 116 0.030
cellular protein modification process GO:0006464 438 0.030
brain development GO:0007420 120 0.030
Mouse
purine nucleoside metabolic process GO:0042278 127 0.030
regulation of cell cycle phase transition GO:1901987 130 0.030
taxis GO:0042330 304 0.030
epithelium migration GO:0090132 148 0.030
response to unfolded protein GO:0006986 9 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.029
apoptotic process involved in development GO:1902742 20 0.029
antibacterial peptide biosynthetic process GO:0002780 22 0.029
glycosyl compound metabolic process GO:1901657 127 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.029
secretion GO:0046903 109 0.029
neuron maturation GO:0042551 31 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
regulation of small gtpase mediated signal transduction GO:0051056 93 0.028
response to virus GO:0009615 28 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
response to x ray GO:0010165 8 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
wing disc morphogenesis GO:0007472 344 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
regulation of programmed cell death GO:0043067 152 0.027
response to organic substance GO:0010033 284 0.027
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.027
chemotaxis GO:0006935 249 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
cellular response to starvation GO:0009267 61 0.026
dna integrity checkpoint GO:0031570 81 0.026
intracellular transport GO:0046907 228 0.026
regulation of cell death GO:0010941 173 0.026
neuromuscular synaptic transmission GO:0007274 67 0.026
regulation of hydrolase activity GO:0051336 97 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
mitotic nuclear division GO:0007067 213 0.026
chorion containing eggshell formation GO:0007304 105 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
positive regulation of cellular catabolic process GO:0031331 95 0.025
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.025
organophosphate metabolic process GO:0019637 195 0.025
aging GO:0007568 143 0.025
chaeta development GO:0022416 97 0.025
mitochondrion organization GO:0007005 65 0.025
cellular response to sterol depletion GO:0071501 3 0.025
positive regulation of antibacterial peptide production GO:0002803 20 0.024
negative regulation of cell proliferation GO:0008285 69 0.024
chromosome segregation GO:0007059 157 0.024
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.024
regulation of neuromuscular synaptic transmission GO:1900073 15 0.024
cellular protein catabolic process GO:0044257 83 0.024
cell cycle arrest GO:0007050 4 0.024
regulation of response to external stimulus GO:0032101 115 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
Mouse
small molecule metabolic process GO:0044281 305 0.024
cell cycle phase transition GO:0044770 140 0.024
regulation of cellular localization GO:0060341 136 0.024
digestive tract morphogenesis GO:0048546 127 0.024
digestive tract development GO:0048565 149 0.024
regulation of cell differentiation GO:0045595 302 0.024
nucleotide catabolic process GO:0009166 109 0.024
nucleus organization GO:0006997 45 0.023
regulation of antibacterial peptide production GO:0002786 22 0.023
antibacterial peptide production GO:0002778 22 0.023
developmental maturation GO:0021700 172 0.023
cellular protein localization GO:0034613 160 0.023
cell maturation GO:0048469 144 0.023
negative regulation of developmental process GO:0051093 201 0.023
positive regulation of response to external stimulus GO:0032103 44 0.023
protein heterooligomerization GO:0051291 4 0.023
regulation of cell development GO:0060284 215 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.023
mating behavior GO:0007617 106 0.023
forebrain development GO:0030900 2 0.022
Mouse
mitotic cell cycle checkpoint GO:0007093 88 0.022
heterocycle catabolic process GO:0046700 166 0.022
Mouse
epithelial cell migration GO:0010631 148 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
er nucleus signaling pathway GO:0006984 9 0.022
peripheral nervous system development GO:0007422 52 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
positive regulation of protein metabolic process GO:0051247 128 0.022
positive regulation of catalytic activity GO:0043085 118 0.021
nucleotide metabolic process GO:0009117 161 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
digestive system development GO:0055123 149 0.021
positive regulation of protein transport GO:0051222 37 0.021
positive regulation of cellular amide metabolic process GO:0034250 26 0.021
positive regulation of immune system process GO:0002684 68 0.021
extrinsic apoptotic signaling pathway GO:0097191 1 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
protein processing GO:0016485 68 0.021
cell cycle checkpoint GO:0000075 95 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
cellular response to nutrient levels GO:0031669 62 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.020
Mouse
regulation of protein localization GO:0032880 76 0.020
border follicle cell migration GO:0007298 113 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
regulation of macroautophagy GO:0016241 15 0.020
single organism biosynthetic process GO:0044711 206 0.020
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.020
positive regulation of multi organism process GO:0043902 40 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of gene expression epigenetic GO:0040029 128 0.020
chromosome organization GO:0051276 360 0.020
protein maturation GO:0051604 71 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
negative regulation of programmed cell death GO:0043069 72 0.020
body morphogenesis GO:0010171 2 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
developmental growth GO:0048589 280 0.019
negative regulation of cell cycle GO:0045786 116 0.019
head involution GO:0008258 35 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
dna packaging GO:0006323 91 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
Mouse
purine containing compound catabolic process GO:0072523 112 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
response to nitrogen compound GO:1901698 90 0.019
regulation of cell proliferation GO:0042127 163 0.019
embryonic pattern specification GO:0009880 174 0.018
positive regulation of response to biotic stimulus GO:0002833 31 0.018
regulation of retinal cell programmed cell death GO:0046668 18 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
ion transport GO:0006811 145 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
cytoplasmic transport GO:0016482 130 0.018
ameboidal type cell migration GO:0001667 151 0.018
nucleocytoplasmic transport GO:0006913 72 0.018
tube development GO:0035295 244 0.017
Mouse
regulation of ras protein signal transduction GO:0046578 93 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
positive regulation of developmental process GO:0051094 143 0.017
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
organelle assembly GO:0070925 198 0.017
response to endogenous stimulus GO:0009719 119 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.017
chemosensory behavior GO:0007635 106 0.017
regulation of cellular response to stress GO:0080135 89 0.017
negative regulation of signal transduction GO:0009968 206 0.017
regulation of autophagy GO:0010506 62 0.017
cellular macromolecule localization GO:0070727 220 0.017
mitotic spindle organization GO:0007052 220 0.016
ectopic germ cell programmed cell death GO:0035234 8 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
regulation of membrane potential GO:0042391 35 0.016
tube morphogenesis GO:0035239 191 0.016
Mouse
gene silencing GO:0016458 138 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
reproductive system development GO:0061458 74 0.016
response to temperature stimulus GO:0009266 106 0.016
regulation of multi organism process GO:0043900 131 0.016
positive regulation of humoral immune response GO:0002922 28 0.016
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
regulation of response to nutrient levels GO:0032107 18 0.015
adult behavior GO:0030534 137 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
ras protein signal transduction GO:0007265 88 0.015
activation of cysteine type endopeptidase activity GO:0097202 17 0.015
membrane depolarization GO:0051899 4 0.015
chromatin organization GO:0006325 207 0.015
gtp catabolic process GO:0006184 72 0.015
actin cytoskeleton organization GO:0030036 206 0.015
telencephalon development GO:0021537 2 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
camera type eye development GO:0043010 4 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
multi organism behavior GO:0051705 175 0.015
cellular response to mechanical stimulus GO:0071260 2 0.015
macroautophagy GO:0016236 42 0.015
dendrite morphogenesis GO:0048813 199 0.014
olfactory behavior GO:0042048 97 0.014
innate immune response GO:0045087 144 0.014
cell recognition GO:0008037 102 0.014
segmentation GO:0035282 207 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
purine containing compound metabolic process GO:0072521 155 0.014
wnt signaling pathway GO:0016055 98 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of protein secretion GO:0050708 13 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
membrane organization GO:0061024 112 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
organophosphate catabolic process GO:0046434 112 0.014
response to decreased oxygen levels GO:0036293 58 0.014
negative regulation of cell death GO:0060548 81 0.014
single organism intracellular transport GO:1902582 207 0.013
rna localization GO:0006403 115 0.013
kidney development GO:0001822 3 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
cellular protein complex assembly GO:0043623 71 0.013
response to oxygen levels GO:0070482 59 0.013
cellular response to organic substance GO:0071310 132 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
open tracheal system development GO:0007424 204 0.013
mitotic cytokinesis GO:0000281 50 0.013
response to lipid GO:0033993 38 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
response to heat GO:0009408 63 0.013
centrosome duplication GO:0051298 121 0.013
response to hexose GO:0009746 3 0.013
cellular ketone metabolic process GO:0042180 24 0.013
tissue migration GO:0090130 155 0.012
positive regulation of antimicrobial peptide production GO:0002225 28 0.012
response to glucose GO:0009749 2 0.012
gtp metabolic process GO:0046039 72 0.012
response to hypoxia GO:0001666 53 0.012
meiotic cell cycle process GO:1903046 132 0.012
regulation of cell shape GO:0008360 113 0.012
establishment of rna localization GO:0051236 47 0.012
androgen metabolic process GO:0008209 1 0.012
asymmetric cell division GO:0008356 37 0.012
regulation of immune system process GO:0002682 176 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
positive regulation of retinal cell programmed cell death GO:0046670 9 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
regulation of secretion GO:0051046 44 0.012
neuron projection guidance GO:0097485 241 0.012
locomotory behavior GO:0007626 176 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
mating GO:0007618 120 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
centrosome organization GO:0051297 163 0.012
negative regulation of immune system process GO:0002683 50 0.012
reproductive structure development GO:0048608 74 0.012
positive regulation of antimicrobial humoral response GO:0002760 28 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
cellular response to external stimulus GO:0071496 66 0.012
wound healing GO:0042060 75 0.012
response to starvation GO:0042594 97 0.012
homeostatic process GO:0042592 199 0.011
regulation of secretion by cell GO:1903530 39 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of anatomical structure size GO:0090066 163 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
growth GO:0040007 359 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
regulation of cell cycle process GO:0010564 181 0.011
cellular lipid metabolic process GO:0044255 83 0.011
mrna processing GO:0006397 104 0.011
endomembrane system organization GO:0010256 119 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
response to alcohol GO:0097305 95 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of meiosis GO:0040020 3 0.011
eggshell chorion assembly GO:0007306 66 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011

Ark disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
central nervous system disease DOID:331 0 0.011