Drosophila melanogaster

84 known processes

Marcal1 (Dmel_CG3753)

CG3753 gene product from transcript CG3753-RA

(Aliases: Dmel\CG3753,CG3753,Marca1)

Marcal1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.112
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.086
cellular response to dna damage stimulus GO:0006974 223 0.076
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.057
eye morphogenesis GO:0048592 260 0.051
compound eye development GO:0048749 307 0.050
macromolecular complex assembly GO:0065003 256 0.050
nuclear division GO:0000280 332 0.050
centrosome duplication GO:0051298 121 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
centrosome organization GO:0051297 163 0.048
heterocycle catabolic process GO:0046700 166 0.048
centrosome cycle GO:0007098 137 0.046
positive regulation of cellular biosynthetic process GO:0031328 316 0.046
cellular catabolic process GO:0044248 372 0.045
protein complex assembly GO:0006461 200 0.045
regulation of organelle organization GO:0033043 196 0.045
regulation of cell cycle process GO:0010564 181 0.043
organic substance catabolic process GO:1901575 308 0.042
microtubule organizing center organization GO:0031023 168 0.042
chromosome organization GO:0051276 360 0.042
regulation of mitotic cell cycle phase transition GO:1901990 130 0.042
regulation of cell differentiation GO:0045595 302 0.042
single organism catabolic process GO:0044712 228 0.041
protein complex biogenesis GO:0070271 201 0.040
intracellular transport GO:0046907 228 0.040
negative regulation of gene expression GO:0010629 387 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
rna processing GO:0006396 147 0.039
negative regulation of cell cycle GO:0045786 116 0.039
negative regulation of rna biosynthetic process GO:1902679 240 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
organelle assembly GO:0070925 198 0.036
positive regulation of rna biosynthetic process GO:1902680 266 0.036
positive regulation of rna metabolic process GO:0051254 271 0.035
catabolic process GO:0009056 409 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.035
Human
establishment of localization in cell GO:0051649 402 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.033
mitotic nuclear division GO:0007067 213 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
regulation of cell cycle GO:0051726 291 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.032
regulation of nervous system development GO:0051960 248 0.032
negative regulation of response to stimulus GO:0048585 258 0.031
negative regulation of transcription dna templated GO:0045892 237 0.031
macromolecule catabolic process GO:0009057 161 0.031
cell proliferation GO:0008283 299 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
regulation of mitosis GO:0007088 56 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
positive regulation of biosynthetic process GO:0009891 316 0.029
regulation of cell development GO:0060284 215 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
positive regulation of signaling GO:0023056 243 0.029
neurological system process GO:0050877 358 0.028
forebrain development GO:0030900 2 0.028
regionalization GO:0003002 416 0.028
positive regulation of gene expression GO:0010628 290 0.028
compound eye morphogenesis GO:0001745 249 0.028
developmental growth GO:0048589 280 0.028
negative regulation of biosynthetic process GO:0009890 277 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
organic substance transport GO:0071702 257 0.027
chromatin organization GO:0006325 207 0.027
cellular macromolecule catabolic process GO:0044265 136 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
chromosome separation GO:0051304 42 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
proteolysis GO:0006508 192 0.026
negative regulation of signal transduction GO:0009968 206 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
growth GO:0040007 359 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
regulation of cell cycle phase transition GO:1901987 130 0.025
response to abiotic stimulus GO:0009628 341 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
dendrite development GO:0016358 204 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
negative regulation of gene expression epigenetic GO:0045814 77 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
dna metabolic process GO:0006259 227 0.024
single organism intracellular transport GO:1902582 207 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
single organism cellular localization GO:1902580 180 0.023
rna localization GO:0006403 115 0.022
chromosome segregation GO:0007059 157 0.022
regulation of protein metabolic process GO:0051246 256 0.022
cell death GO:0008219 279 0.022
regulation of nuclear division GO:0051783 58 0.021
response to external biotic stimulus GO:0043207 293 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
programmed cell death GO:0012501 257 0.021
cell maturation GO:0048469 144 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
small molecule metabolic process GO:0044281 305 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
mitotic g2 dna damage checkpoint GO:0007095 69 0.021
positive regulation of signal transduction GO:0009967 223 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of cell division GO:0051302 72 0.020
vesicle mediated transport GO:0016192 381 0.020
cellular macromolecule localization GO:0070727 220 0.020
cytoplasmic transport GO:0016482 130 0.020
protein catabolic process GO:0030163 101 0.020
positive regulation of cell communication GO:0010647 250 0.020
regulation of neurogenesis GO:0050767 158 0.020
regulation of localization GO:0032879 275 0.019
aromatic compound catabolic process GO:0019439 166 0.019
cellular protein localization GO:0034613 160 0.019
antimicrobial humoral response GO:0019730 99 0.019
cellular ketone metabolic process GO:0042180 24 0.019
negative regulation of cell communication GO:0010648 223 0.019
salivary gland development GO:0007431 162 0.019
leg disc development GO:0035218 92 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
mitotic g2 m transition checkpoint GO:0044818 70 0.018
response to organic substance GO:0010033 284 0.018
protein localization GO:0008104 284 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
cell cycle phase transition GO:0044770 140 0.018
response to nutrient levels GO:0031667 114 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
regulation of catabolic process GO:0009894 170 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
Human
mrna metabolic process GO:0016071 124 0.017
chemotaxis GO:0006935 249 0.017
response to biotic stimulus GO:0009607 294 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
negative regulation of developmental process GO:0051093 201 0.017
phagocytosis GO:0006909 215 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
response to lipopolysaccharide GO:0032496 4 0.017
endocytosis GO:0006897 310 0.017
homeostatic process GO:0042592 199 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
negative regulation of signaling GO:0023057 219 0.016
organophosphate metabolic process GO:0019637 195 0.016
organic acid metabolic process GO:0006082 103 0.016
sister chromatid segregation GO:0000819 92 0.016
protein modification process GO:0036211 438 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
developmental maturation GO:0021700 172 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
cellular protein modification process GO:0006464 438 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
regulation of molecular function GO:0065009 217 0.016
tissue morphogenesis GO:0048729 297 0.016
appendage development GO:0048736 401 0.016
spindle organization GO:0007051 253 0.015
mitochondrion organization GO:0007005 65 0.015
immune system process GO:0002376 347 0.015
mrna processing GO:0006397 104 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
positive regulation of cell motility GO:2000147 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
oxoacid metabolic process GO:0043436 103 0.015
protein transport GO:0015031 155 0.015
wing disc morphogenesis GO:0007472 344 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
regulation of response to stress GO:0080134 200 0.014
purine containing compound metabolic process GO:0072521 155 0.014
protein dna complex subunit organization GO:0071824 86 0.014
regulation of cellular component size GO:0032535 98 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
lateral inhibition GO:0046331 206 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
response to radiation GO:0009314 155 0.014
intracellular protein transport GO:0006886 104 0.014
eye development GO:0001654 323 0.014
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.014
regulation of cell proliferation GO:0042127 163 0.014
leg disc morphogenesis GO:0007478 80 0.014
cell fate determination GO:0001709 91 0.014
dna repair GO:0006281 54 0.014
proteasomal protein catabolic process GO:0010498 59 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
apoptotic process GO:0006915 159 0.013
nucleotide catabolic process GO:0009166 109 0.013
cell cycle checkpoint GO:0000075 95 0.013
amine metabolic process GO:0009308 12 0.013
detection of stimulus GO:0051606 156 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
cell division GO:0051301 248 0.013
regulation of cellular localization GO:0060341 136 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
chromatin remodeling GO:0006338 72 0.013
sensory organ morphogenesis GO:0090596 260 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
segmentation GO:0035282 207 0.013
regulation of immune response GO:0050776 118 0.013
positive regulation of cell migration GO:0030335 2 0.013
regulation of cellular response to stress GO:0080135 89 0.013
intracellular signal transduction GO:0035556 300 0.013
open tracheal system development GO:0007424 204 0.013
gene silencing GO:0016458 138 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
negative regulation of growth GO:0045926 84 0.013
appendage morphogenesis GO:0035107 397 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
response to organic cyclic compound GO:0014070 89 0.013
positive regulation of transport GO:0051050 92 0.013
regulation of immune system process GO:0002682 176 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
tube morphogenesis GO:0035239 191 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
chromatin modification GO:0016568 147 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
taxis GO:0042330 304 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
endomembrane system organization GO:0010256 119 0.012
respiratory system development GO:0060541 213 0.012
purine containing compound catabolic process GO:0072523 112 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
epithelial cell development GO:0002064 274 0.012
maintenance of location GO:0051235 73 0.012
gland morphogenesis GO:0022612 145 0.012
regulation of protein catabolic process GO:0042176 55 0.012
brain development GO:0007420 120 0.012
cellular protein complex assembly GO:0043623 71 0.012
exocrine system development GO:0035272 162 0.012
imaginal disc pattern formation GO:0007447 91 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of neuron differentiation GO:0045664 103 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
regulation of chromosome segregation GO:0051983 32 0.012
spermatogenesis GO:0007283 200 0.012
establishment of rna localization GO:0051236 47 0.012
nucleobase containing compound transport GO:0015931 56 0.012
cellular amine metabolic process GO:0044106 12 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
r7 cell differentiation GO:0045466 43 0.012
nucleosome organization GO:0034728 59 0.012
metaphase anaphase transition of cell cycle GO:0044784 28 0.012
death GO:0016265 284 0.012
connective tissue development GO:0061448 3 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
mitotic sister chromatid separation GO:0051306 30 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
defense response GO:0006952 300 0.011
dorsal ventral axis specification GO:0009950 66 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
response to other organism GO:0051707 293 0.011
single organism biosynthetic process GO:0044711 206 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
mitotic spindle organization GO:0007052 220 0.011
telencephalon development GO:0021537 2 0.011
histolysis GO:0007559 102 0.011
single organism membrane organization GO:0044802 93 0.011
protein processing GO:0016485 68 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
dna packaging GO:0006323 91 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
cellular protein catabolic process GO:0044257 83 0.011
tissue death GO:0016271 102 0.011
ovarian follicle cell development GO:0030707 248 0.011
dna conformation change GO:0071103 105 0.011
oocyte differentiation GO:0009994 145 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
dna damage checkpoint GO:0000077 78 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
g2 dna damage checkpoint GO:0031572 69 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.010
ras protein signal transduction GO:0007265 88 0.010
chaeta development GO:0022416 97 0.010
gland development GO:0048732 191 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
dna dependent dna replication GO:0006261 17 0.010
Human
central nervous system development GO:0007417 201 0.010
axon development GO:0061564 297 0.010
positive regulation of molecular function GO:0044093 136 0.010
eggshell formation GO:0030703 105 0.010
dendrite morphogenesis GO:0048813 199 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010

Marcal1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
hair disease DOID:421 0 0.019
integumentary system disease DOID:16 0 0.019
disease of metabolism DOID:0014667 0 0.017