Drosophila melanogaster

39 known processes

Pkd2 (Dmel_CG6504)

Polycystic kidney disease gene-2

(Aliases: Dmpkd2,AMO,Amo,amo,PKD2,CG6504,Dmel\CG6504,pkd2)

Pkd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sperm motility GO:0030317 12 0.847
circadian behavior GO:0048512 76 0.340
single organism behavior GO:0044708 391 0.339
male gamete generation GO:0048232 201 0.321
negative regulation of response to stimulus GO:0048585 258 0.292
neurological system process GO:0050877 358 0.290
rhythmic behavior GO:0007622 76 0.269
rhythmic process GO:0048511 106 0.250
spermatogenesis GO:0007283 200 0.218
multi multicellular organism process GO:0044706 123 0.217
larval feeding behavior GO:0030536 15 0.209
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.203
negative regulation of cell communication GO:0010648 223 0.154
circadian rhythm GO:0007623 105 0.147
wing disc morphogenesis GO:0007472 344 0.147
mating GO:0007618 120 0.143
cell motility GO:0048870 251 0.140
neuropeptide signaling pathway GO:0007218 45 0.138
negative regulation of signal transduction GO:0009968 206 0.135
negative regulation of signaling GO:0023057 219 0.135
regulation of cell differentiation GO:0045595 302 0.133
multi organism reproductive behavior GO:0044705 121 0.133
positive regulation of macromolecule metabolic process GO:0010604 405 0.129
cell maturation GO:0048469 144 0.122
regionalization GO:0003002 416 0.121
activation of cysteine type endopeptidase activity GO:0097202 17 0.121
localization of cell GO:0051674 257 0.113
spermatid differentiation GO:0048515 114 0.107
eye development GO:0001654 323 0.105
response to temperature stimulus GO:0009266 106 0.103
response to abiotic stimulus GO:0009628 341 0.103
cell division GO:0051301 248 0.102
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.100
regulation of localization GO:0032879 275 0.098
positive regulation of endopeptidase activity GO:0010950 26 0.097
imaginal disc derived wing morphogenesis GO:0007476 337 0.097
spermatid development GO:0007286 98 0.091
spindle organization GO:0007051 253 0.090
olfactory learning GO:0008355 56 0.088
sleep GO:0030431 49 0.088
immune system process GO:0002376 347 0.086
memory GO:0007613 94 0.084
tripartite regional subdivision GO:0007351 103 0.083
insemination GO:0007320 22 0.077
negative regulation of transcription dna templated GO:0045892 237 0.073
developmental maturation GO:0021700 172 0.072
post embryonic appendage morphogenesis GO:0035120 385 0.072
regulation of embryonic development GO:0045995 68 0.071
regulation of cell development GO:0060284 215 0.071
organic substance transport GO:0071702 257 0.069
regulation of multicellular organismal development GO:2000026 414 0.068
locomotory behavior GO:0007626 176 0.067
camera type eye development GO:0043010 4 0.067
multicellular organismal reproductive behavior GO:0033057 110 0.067
zymogen activation GO:0031638 20 0.063
appendage morphogenesis GO:0035107 397 0.063
multi organism behavior GO:0051705 175 0.062
learning or memory GO:0007611 141 0.062
g protein coupled receptor signaling pathway GO:0007186 136 0.062
oocyte axis specification GO:0007309 108 0.061
regulation of endopeptidase activity GO:0052548 36 0.061
protein modification process GO:0036211 438 0.061
regulation of behavior GO:0050795 75 0.061
courtship behavior GO:0007619 68 0.060
pole plasm rna localization GO:0007316 52 0.059
circadian sleep wake cycle GO:0042745 28 0.059
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.059
negative regulation of cellular metabolic process GO:0031324 382 0.058
maintenance of location GO:0051235 73 0.058
circadian sleep wake cycle process GO:0022410 24 0.055
negative regulation of gene expression GO:0010629 387 0.054
regulation of anatomical structure morphogenesis GO:0022603 242 0.054
proteolysis GO:0006508 192 0.052
regulation of cellular protein metabolic process GO:0032268 243 0.051
sperm individualization GO:0007291 48 0.051
olfactory behavior GO:0042048 97 0.050
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.049
cellular macromolecule catabolic process GO:0044265 136 0.049
enzyme linked receptor protein signaling pathway GO:0007167 179 0.049
reproductive behavior GO:0019098 122 0.049
cellular catabolic process GO:0044248 372 0.048
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
defense response to bacterium GO:0042742 178 0.048
cell death GO:0008219 279 0.047
segmentation GO:0035282 207 0.046
positive regulation of biosynthetic process GO:0009891 316 0.046
oocyte construction GO:0007308 112 0.046
regulation of oocyte development GO:0060281 27 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
male courtship behavior GO:0008049 63 0.044
programmed cell death GO:0012501 257 0.044
oocyte development GO:0048599 124 0.044
chemosensory behavior GO:0007635 106 0.043
vesicle mediated transport GO:0016192 381 0.042
phosphorylation GO:0016310 294 0.042
cellular protein modification process GO:0006464 438 0.042
organic substance catabolic process GO:1901575 308 0.042
regulation of catalytic activity GO:0050790 185 0.041
embryonic morphogenesis GO:0048598 206 0.041
positive regulation of molecular function GO:0044093 136 0.041
appendage development GO:0048736 401 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
posttranscriptional gene silencing GO:0016441 46 0.041
central nervous system development GO:0007417 201 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
regulation of response to external stimulus GO:0032101 115 0.040
cognition GO:0050890 141 0.039
regulation of molecular function GO:0065009 217 0.039
regulation of protein metabolic process GO:0051246 256 0.039
negative regulation of wnt signaling pathway GO:0030178 28 0.038
male mating behavior GO:0060179 70 0.038
rna localization GO:0006403 115 0.038
cytoplasm organization GO:0007028 64 0.037
smoothened signaling pathway GO:0007224 49 0.037
anterior posterior axis specification embryo GO:0008595 103 0.037
neuron maturation GO:0042551 31 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.037
organonitrogen compound metabolic process GO:1901564 318 0.036
positive regulation of response to stimulus GO:0048584 323 0.036
regulation of programmed cell death GO:0043067 152 0.036
positive regulation of apoptotic signaling pathway GO:2001235 4 0.036
regulation of proteolysis GO:0030162 87 0.035
cell proliferation GO:0008283 299 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
positive regulation of catalytic activity GO:0043085 118 0.034
catabolic process GO:0009056 409 0.034
defense response to other organism GO:0098542 225 0.034
regulation of smoothened signaling pathway GO:0008589 28 0.034
mrna metabolic process GO:0016071 124 0.034
oocyte anterior posterior axis specification GO:0007314 72 0.034
single organism intracellular transport GO:1902582 207 0.033
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.033
establishment or maintenance of cell polarity GO:0007163 167 0.033
regulation of catabolic process GO:0009894 170 0.033
blastoderm segmentation GO:0007350 159 0.032
regulation of response to nutrient levels GO:0032107 18 0.032
regulation of response to stress GO:0080134 200 0.032
regulation of circadian sleep wake cycle GO:0042749 25 0.031
neuron remodeling GO:0016322 29 0.031
axis specification GO:0009798 167 0.030
response to nutrient levels GO:0031667 114 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.030
positive regulation of hydrolase activity GO:0051345 78 0.030
regulation of peptidase activity GO:0052547 39 0.030
digestive system development GO:0055123 149 0.029
response to other organism GO:0051707 293 0.029
regulation of cysteine type endopeptidase activity GO:2000116 27 0.029
negative regulation of biosynthetic process GO:0009890 277 0.028
macromolecule catabolic process GO:0009057 161 0.028
regulation of multi organism process GO:0043900 131 0.028
forebrain development GO:0030900 2 0.028
immune response GO:0006955 246 0.028
imaginal disc pattern formation GO:0007447 91 0.028
intracellular mrna localization GO:0008298 66 0.028
posttranscriptional gene silencing by rna GO:0035194 45 0.028
positive regulation of cellular protein metabolic process GO:0032270 118 0.028
pole plasm mrna localization GO:0019094 49 0.028
retina development in camera type eye GO:0060041 4 0.027
small molecule metabolic process GO:0044281 305 0.027
positive regulation of protein metabolic process GO:0051247 128 0.027
regulation of apoptotic process GO:0042981 130 0.027
dendrite development GO:0016358 204 0.027
protein phosphorylation GO:0006468 169 0.026
nuclear division GO:0000280 332 0.026
regulation of immune system process GO:0002682 176 0.026
death GO:0016265 284 0.026
protein modification by small protein conjugation or removal GO:0070647 106 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
embryonic axis specification GO:0000578 107 0.026
regulation of hydrolase activity GO:0051336 97 0.026
gene silencing by rna GO:0031047 57 0.026
synaptic transmission GO:0007268 288 0.026
response to extracellular stimulus GO:0009991 116 0.026
regulation of cellular localization GO:0060341 136 0.026
regulation of embryonic pattern specification GO:1902875 27 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
cellularization GO:0007349 90 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
positive regulation of proteolysis GO:0045862 52 0.025
intracellular signal transduction GO:0035556 300 0.025
phagocytosis GO:0006909 215 0.025
anterior posterior pattern specification GO:0009952 136 0.025
growth GO:0040007 359 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
regulation of reproductive process GO:2000241 54 0.024
cellular macromolecule localization GO:0070727 220 0.024
protein maturation GO:0051604 71 0.024
pole plasm assembly GO:0007315 61 0.024
positive regulation of peptidase activity GO:0010952 29 0.024
gland morphogenesis GO:0022612 145 0.024
regulation of pole plasm oskar mrna localization GO:0007317 27 0.024
l amino acid import GO:0043092 2 0.024
digestive tract development GO:0048565 149 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.023
positive regulation of nervous system development GO:0051962 69 0.023
immune system development GO:0002520 57 0.023
positive regulation of signal transduction GO:0009967 223 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
wnt signaling pathway GO:0016055 98 0.023
lipid localization GO:0010876 54 0.023
feeding behavior GO:0007631 50 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.022
positive regulation of cell communication GO:0010647 250 0.022
regulation of circadian rhythm GO:0042752 49 0.022
associative learning GO:0008306 65 0.022
apoptotic process GO:0006915 159 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
chromosome segregation GO:0007059 157 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
hematopoietic or lymphoid organ development GO:0048534 57 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
cytoplasmic transport GO:0016482 130 0.022
regulation of cell maturation GO:1903429 27 0.022
tube morphogenesis GO:0035239 191 0.021
positive regulation of gene expression GO:0010628 290 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
oocyte differentiation GO:0009994 145 0.021
organic anion transport GO:0015711 28 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
intracellular transport GO:0046907 228 0.020
regulation of nervous system development GO:0051960 248 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
molting cycle chitin based cuticle GO:0007591 56 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
maternal determination of anterior posterior axis embryo GO:0008358 74 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
defense response GO:0006952 300 0.020
endocytosis GO:0006897 310 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
long term memory GO:0007616 62 0.020
regulation of neurogenesis GO:0050767 158 0.019
anterior posterior pattern specification imaginal disc GO:0007448 16 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
regulation of synaptic transmission GO:0050804 69 0.019
nitrogen compound transport GO:0071705 85 0.019
rna processing GO:0006396 147 0.019
regulation of cell cycle GO:0051726 291 0.019
lipid storage GO:0019915 38 0.019
protein catabolic process GO:0030163 101 0.019
chromosome separation GO:0051304 42 0.019
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.019
protein modification by small protein conjugation GO:0032446 79 0.018
macromolecular complex assembly GO:0065003 256 0.018
protein ubiquitination GO:0016567 70 0.018
protein processing GO:0016485 68 0.018
positive regulation of developmental process GO:0051094 143 0.018
gene silencing GO:0016458 138 0.018
anterior posterior axis specification GO:0009948 109 0.018
establishment of localization in cell GO:0051649 402 0.018
response to biotic stimulus GO:0009607 294 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
organelle localization GO:0051640 148 0.017
organic acid metabolic process GO:0006082 103 0.017
regulation of immune response GO:0050776 118 0.017
larval behavior GO:0030537 42 0.017
oxidation reduction process GO:0055114 123 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
transmembrane transport GO:0055085 139 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
aromatic compound catabolic process GO:0019439 166 0.017
mrna catabolic process GO:0006402 33 0.017
chromosome organization GO:0051276 360 0.017
response to external biotic stimulus GO:0043207 293 0.017
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
purine containing compound metabolic process GO:0072521 155 0.017
cellular response to organic substance GO:0071310 132 0.017
response to heat GO:0009408 63 0.017
regulation of cell proliferation GO:0042127 163 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
cellular protein catabolic process GO:0044257 83 0.016
learning GO:0007612 75 0.016
exocrine system development GO:0035272 162 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
oocyte microtubule cytoskeleton organization GO:0016325 35 0.016
positive regulation of immune system process GO:0002684 68 0.016
sensory perception GO:0007600 196 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
negative regulation of smoothened signaling pathway GO:0045879 16 0.016
intraspecies interaction between organisms GO:0051703 4 0.016
meiotic cell cycle process GO:1903046 132 0.016
regulation of wnt protein secretion GO:0061356 5 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
regulation of neuron differentiation GO:0045664 103 0.016
single organism catabolic process GO:0044712 228 0.016
response to bacterium GO:0009617 198 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
regulation of defense response GO:0031347 102 0.015
sensory organ morphogenesis GO:0090596 260 0.015
positive regulation of cell death GO:0010942 69 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
single organism cellular localization GO:1902580 180 0.015
single organism membrane organization GO:0044802 93 0.015
positive regulation of cell motility GO:2000147 3 0.015
response to organic substance GO:0010033 284 0.015
positive regulation of signaling GO:0023056 243 0.015
response to glucose GO:0009749 2 0.015
positive regulation of cell development GO:0010720 61 0.015
embryonic pattern specification GO:0009880 174 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
organelle fission GO:0048285 340 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
autophagy GO:0006914 108 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
regulation of cell death GO:0010941 173 0.014
protein complex disassembly GO:0043241 36 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
response to oxygen containing compound GO:1901700 200 0.014
mapk cascade GO:0000165 107 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
cellular amine metabolic process GO:0044106 12 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of retinal cell programmed cell death GO:0046668 18 0.014
positive regulation of apoptotic process GO:0043065 47 0.013
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
eye morphogenesis GO:0048592 260 0.013
protein localization GO:0008104 284 0.013
protein complex biogenesis GO:0070271 201 0.013
oxoacid metabolic process GO:0043436 103 0.013
asymmetric cell division GO:0008356 37 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
regulation of phosphorylation GO:0042325 147 0.013
ameboidal type cell migration GO:0001667 151 0.013
gliogenesis GO:0042063 80 0.013
open tracheal system development GO:0007424 204 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
protein heterooligomerization GO:0051291 4 0.013
pigmentation GO:0043473 75 0.013
nucleotide metabolic process GO:0009117 161 0.013
endomembrane system organization GO:0010256 119 0.013
compound eye development GO:0048749 307 0.013
amine metabolic process GO:0009308 12 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
response to monosaccharide GO:0034284 4 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
response to organonitrogen compound GO:0010243 75 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
developmental growth GO:0048589 280 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
sensory perception of sound GO:0007605 56 0.012
regulation of cellular component size GO:0032535 98 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
digestive tract morphogenesis GO:0048546 127 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
spinal cord development GO:0021510 1 0.012
cellular ketone metabolic process GO:0042180 24 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
meiotic cell cycle GO:0051321 171 0.012
copulation GO:0007620 26 0.012
dendrite morphogenesis GO:0048813 199 0.012
rna 3 end processing GO:0031123 45 0.012
protein complex assembly GO:0006461 200 0.012
somatic stem cell division GO:0048103 37 0.012
mating behavior GO:0007617 106 0.012
cellular protein localization GO:0034613 160 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
body morphogenesis GO:0010171 2 0.012
thermosensory behavior GO:0040040 19 0.011
regulation of response to extracellular stimulus GO:0032104 18 0.011
cellular component disassembly GO:0022411 46 0.011
protein transport GO:0015031 155 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
response to growth factor GO:0070848 31 0.011
germ line stem cell maintenance GO:0030718 50 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
regulation of protein modification process GO:0031399 112 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
regulation of cell division GO:0051302 72 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of cellular response to stress GO:0080135 89 0.011
positive regulation of catabolic process GO:0009896 105 0.011
nucleoside metabolic process GO:0009116 127 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
dna damage checkpoint GO:0000077 78 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
positive regulation of neuron differentiation GO:0045666 26 0.011
dna integrity checkpoint GO:0031570 81 0.011
compound eye retinal cell programmed cell death GO:0046667 23 0.011
positive regulation of protein modification process GO:0031401 58 0.011
microtubule based transport GO:0010970 42 0.011
monocarboxylic acid transport GO:0015718 3 0.010
regulation of organ morphogenesis GO:2000027 78 0.010
macromolecular complex disassembly GO:0032984 37 0.010
regulation of anatomical structure size GO:0090066 163 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
atp metabolic process GO:0046034 49 0.010
heterocycle catabolic process GO:0046700 166 0.010
gland development GO:0048732 191 0.010
male meiosis GO:0007140 52 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010

Pkd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013