Drosophila melanogaster

50 known processes

ssp4 (Dmel_CG33130)

short spindle 4

(Aliases: CG6516,CG18462,CG30102,CG18460,Dmel\CG33130,BcDNA:LD17191,CG18459,l(2)k07433,Ssp4,CG33130)

ssp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 308 0.114
vesicle mediated transport GO:0016192 381 0.105
cellular catabolic process GO:0044248 372 0.085
programmed cell death GO:0012501 257 0.080
protein modification process GO:0036211 438 0.075
cellular nitrogen compound catabolic process GO:0044270 165 0.075
cell death GO:0008219 279 0.073
protein modification by small protein conjugation or removal GO:0070647 106 0.064
aromatic compound catabolic process GO:0019439 166 0.061
death GO:0016265 284 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.059
positive regulation of gtpase activity GO:0043547 43 0.059
organonitrogen compound metabolic process GO:1901564 318 0.057
purine nucleoside triphosphate metabolic process GO:0009144 119 0.054
single organism intracellular transport GO:1902582 207 0.054
protein ubiquitination GO:0016567 70 0.053
heterocycle catabolic process GO:0046700 166 0.052
establishment of localization in cell GO:0051649 402 0.051
intracellular signal transduction GO:0035556 300 0.050
nucleotide catabolic process GO:0009166 109 0.050
enzyme linked receptor protein signaling pathway GO:0007167 179 0.048
nucleoside triphosphate catabolic process GO:0009143 108 0.048
purine ribonucleoside catabolic process GO:0046130 112 0.047
purine nucleoside metabolic process GO:0042278 127 0.047
regulation of organelle organization GO:0033043 196 0.045
guanosine containing compound metabolic process GO:1901068 74 0.045
ribonucleoside triphosphate metabolic process GO:0009199 119 0.044
purine nucleoside catabolic process GO:0006152 112 0.043
apoptotic process GO:0006915 159 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.043
nucleobase containing compound catabolic process GO:0034655 165 0.042
catabolic process GO:0009056 409 0.041
endocytosis GO:0006897 310 0.040
cellular response to dna damage stimulus GO:0006974 223 0.039
ribonucleoside triphosphate catabolic process GO:0009203 108 0.039
endosomal transport GO:0016197 44 0.039
nucleoside phosphate catabolic process GO:1901292 110 0.039
organophosphate metabolic process GO:0019637 195 0.037
post golgi vesicle mediated transport GO:0006892 11 0.037
regulation of catalytic activity GO:0050790 185 0.037
nucleoside triphosphate metabolic process GO:0009141 120 0.037
intracellular transport GO:0046907 228 0.037
organic cyclic compound catabolic process GO:1901361 168 0.036
single organism membrane organization GO:0044802 93 0.036
developmental maturation GO:0021700 172 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.036
single organism behavior GO:0044708 391 0.036
nucleotide metabolic process GO:0009117 161 0.036
single organism catabolic process GO:0044712 228 0.036
cellular protein modification process GO:0006464 438 0.035
regulation of cellular component biogenesis GO:0044087 201 0.035
ribonucleotide metabolic process GO:0009259 145 0.034
lateral inhibition GO:0046331 206 0.034
purine containing compound metabolic process GO:0072521 155 0.034
ribose phosphate metabolic process GO:0019693 145 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
nucleoside catabolic process GO:0009164 112 0.033
ribonucleoside catabolic process GO:0042454 112 0.033
regulation of cellular response to stress GO:0080135 89 0.033
purine containing compound catabolic process GO:0072523 112 0.032
chromosome organization GO:0051276 360 0.032
morphogenesis of an epithelium GO:0002009 276 0.032
regulation of cell cycle GO:0051726 291 0.032
purine ribonucleoside metabolic process GO:0046128 127 0.031
wing disc morphogenesis GO:0007472 344 0.031
purine nucleotide catabolic process GO:0006195 109 0.031
phosphorylation GO:0016310 294 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.031
erbb signaling pathway GO:0038127 58 0.030
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
negative regulation of response to stimulus GO:0048585 258 0.029
regulation of response to stress GO:0080134 200 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
immune system process GO:0002376 347 0.029
glycosyl compound metabolic process GO:1901657 127 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
organelle localization GO:0051640 148 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
compound eye development GO:0048749 307 0.027
regulation of intracellular signal transduction GO:1902531 236 0.027
cell motility GO:0048870 251 0.027
appendage development GO:0048736 401 0.027
regulation of programmed cell death GO:0043067 152 0.027
negative regulation of signaling GO:0023057 219 0.027
positive regulation of ras gtpase activity GO:0032320 36 0.027
phagocytosis GO:0006909 215 0.027
protein localization GO:0008104 284 0.027
detection of chemical stimulus GO:0009593 93 0.027
ribonucleoside metabolic process GO:0009119 127 0.027
macromolecule catabolic process GO:0009057 161 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
regionalization GO:0003002 416 0.026
regulation of cell death GO:0010941 173 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
positive regulation of cellular component organization GO:0051130 156 0.026
purine ribonucleotide catabolic process GO:0009154 109 0.026
organophosphate catabolic process GO:0046434 112 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
positive regulation of nucleoside metabolic process GO:0045979 47 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.024
purine nucleoside triphosphate catabolic process GO:0009146 108 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
response to radiation GO:0009314 155 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
response to abiotic stimulus GO:0009628 341 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
small molecule metabolic process GO:0044281 305 0.024
guanosine containing compound catabolic process GO:1901069 74 0.024
ameboidal type cell migration GO:0001667 151 0.024
defense response GO:0006952 300 0.023
tissue migration GO:0090130 155 0.022
cellularization GO:0007349 90 0.022
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.022
microtubule based transport GO:0010970 42 0.022
endoplasmic reticulum organization GO:0007029 13 0.022
regulation of localization GO:0032879 275 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.021
embryonic morphogenesis GO:0048598 206 0.021
positive regulation of cellular catabolic process GO:0031331 95 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
eye morphogenesis GO:0048592 260 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
epidermal growth factor receptor signaling pathway GO:0007173 58 0.020
chromosome segregation GO:0007059 157 0.020
epithelial cell migration GO:0010631 148 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
chromatin organization GO:0006325 207 0.020
body morphogenesis GO:0010171 2 0.020
glycosyl compound catabolic process GO:1901658 112 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of molecular function GO:0065009 217 0.019
antimicrobial humoral response GO:0019730 99 0.019
regulation of apoptotic process GO:0042981 130 0.019
regulation of nervous system development GO:0051960 248 0.019
negative regulation of signal transduction GO:0009968 206 0.019
compound eye morphogenesis GO:0001745 249 0.019
actin filament organization GO:0007015 126 0.019
regulation of anatomical structure size GO:0090066 163 0.019
regulation of neurogenesis GO:0050767 158 0.019
limb development GO:0060173 1 0.019
spermatogenesis GO:0007283 200 0.019
golgi vesicle transport GO:0048193 27 0.019
digestive tract development GO:0048565 149 0.019
organonitrogen compound catabolic process GO:1901565 128 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
mitotic spindle organization GO:0007052 220 0.018
regulation of protein metabolic process GO:0051246 256 0.018
digestive tract morphogenesis GO:0048546 127 0.018
exocrine system development GO:0035272 162 0.018
positive regulation of cell death GO:0010942 69 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
positive regulation of signal transduction GO:0009967 223 0.018
photoreceptor cell fate commitment GO:0046552 41 0.017
regulation of erbb signaling pathway GO:1901184 42 0.017
endomembrane system organization GO:0010256 119 0.017
nucleoside metabolic process GO:0009116 127 0.017
sister chromatid segregation GO:0000819 92 0.017
regulation of catabolic process GO:0009894 170 0.017
macromolecular complex assembly GO:0065003 256 0.017
positive regulation of transport GO:0051050 92 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
negative regulation of gene expression GO:0010629 387 0.017
regulation of transport GO:0051049 181 0.016
cell division GO:0051301 248 0.016
mitotic nuclear division GO:0007067 213 0.016
synapse organization GO:0050808 196 0.016
cell migration GO:0016477 238 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
regulation of cellular localization GO:0060341 136 0.016
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.016
negative regulation of cell death GO:0060548 81 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
meiotic cell cycle process GO:1903046 132 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
axon development GO:0061564 297 0.015
cytoplasmic transport GO:0016482 130 0.015
positive regulation of gtp catabolic process GO:0033126 43 0.015
epithelial cell development GO:0002064 274 0.015
negative regulation of cell communication GO:0010648 223 0.015
cellular macromolecule localization GO:0070727 220 0.015
regulation of cell cycle process GO:0010564 181 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
response to oxygen containing compound GO:1901700 200 0.015
regulation of synapse organization GO:0050807 110 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
regulation of cell size GO:0008361 63 0.015
cellular response to organic substance GO:0071310 132 0.015
negative regulation of erbb signaling pathway GO:1901185 29 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
dendrite development GO:0016358 204 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of cell development GO:0060284 215 0.015
spermatid development GO:0007286 98 0.015
cell proliferation GO:0008283 299 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
epithelium migration GO:0090132 148 0.014
receptor clustering GO:0043113 3 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
response to other organism GO:0051707 293 0.014
membrane organization GO:0061024 112 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
tissue morphogenesis GO:0048729 297 0.014
reproductive system development GO:0061458 74 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
eye development GO:0001654 323 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
protein phosphorylation GO:0006468 169 0.014
eye photoreceptor cell development GO:0042462 81 0.014
appendage morphogenesis GO:0035107 397 0.013
regulation of nucleotide catabolic process GO:0030811 48 0.013
cellular protein localization GO:0034613 160 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
centrosome organization GO:0051297 163 0.013
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.013
spindle organization GO:0007051 253 0.013
microtubule based movement GO:0007018 51 0.013
developmental programmed cell death GO:0010623 138 0.013
cell maturation GO:0048469 144 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
camera type eye development GO:0043010 4 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
mapk cascade GO:0000165 107 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of mapk cascade GO:0043408 92 0.013
localization of cell GO:0051674 257 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of catabolic process GO:0009896 105 0.012
insulin receptor signaling pathway GO:0008286 25 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
peptidyl lysine modification GO:0018205 57 0.012
cuticle development GO:0042335 86 0.012
connective tissue development GO:0061448 3 0.012
regulation of gtp catabolic process GO:0033124 44 0.012
positive regulation of jun kinase activity GO:0043507 4 0.012
nuclear division GO:0000280 332 0.012
rrna processing GO:0006364 3 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
regulation of cellular component size GO:0032535 98 0.012
vesicle organization GO:0016050 44 0.012
regulation of protein modification process GO:0031399 112 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
organic substance transport GO:0071702 257 0.012
single organism cellular localization GO:1902580 180 0.012
dephosphorylation GO:0016311 51 0.012
cation homeostasis GO:0055080 51 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
sperm individualization GO:0007291 48 0.012
sensory organ morphogenesis GO:0090596 260 0.012
microtubule bundle formation GO:0001578 27 0.012
protein modification by small protein removal GO:0070646 28 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
protein transport GO:0015031 155 0.011
response to biotic stimulus GO:0009607 294 0.011
salivary gland morphogenesis GO:0007435 145 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
covalent chromatin modification GO:0016569 106 0.011
peptidyl amino acid modification GO:0018193 105 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
telencephalon development GO:0021537 2 0.011
limb morphogenesis GO:0035108 1 0.011
growth GO:0040007 359 0.011
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
golgi organization GO:0007030 66 0.011
cellular ketone metabolic process GO:0042180 24 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
rho protein signal transduction GO:0007266 14 0.011
photoreceptor cell development GO:0042461 96 0.011
chromatin modification GO:0016568 147 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
protein complex assembly GO:0006461 200 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
tissue death GO:0016271 102 0.011
cation transmembrane transport GO:0098655 88 0.011
mrna processing GO:0006397 104 0.011
male gamete generation GO:0048232 201 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
actin filament based process GO:0030029 220 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
taxis GO:0042330 304 0.011
response to organic substance GO:0010033 284 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cell recognition GO:0008037 102 0.011
organelle fission GO:0048285 340 0.011
protein dephosphorylation GO:0006470 27 0.011
response to external biotic stimulus GO:0043207 293 0.011
cilium morphogenesis GO:0060271 39 0.011
dendrite morphogenesis GO:0048813 199 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
establishment of protein localization GO:0045184 163 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
dna metabolic process GO:0006259 227 0.010
regulation of synapse assembly GO:0051963 94 0.010
regulation of cell differentiation GO:0045595 302 0.010
actin cytoskeleton organization GO:0030036 206 0.010
regulation of hydrolase activity GO:0051336 97 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
defense response to bacterium GO:0042742 178 0.010
histone modification GO:0016570 106 0.010
karyosome formation GO:0030717 22 0.010
peptidyl threonine modification GO:0018210 3 0.010
response to heat GO:0009408 63 0.010
respiratory system development GO:0060541 213 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
regulation of rna splicing GO:0043484 69 0.010
neurological system process GO:0050877 358 0.010
cellular response to insulin stimulus GO:0032869 28 0.010
autophagy GO:0006914 108 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
positive regulation of apoptotic process GO:0043065 47 0.010

ssp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of metabolism DOID:0014667 0 0.016
nervous system disease DOID:863 0 0.016
inherited metabolic disorder DOID:655 0 0.011