Drosophila melanogaster

156 known processes

sli (Dmel_CG8355)

slit

(Aliases: CT37068,Dmel\CG8355,wdh,CT21700,l(2)05248,Slit,CG8355,dSlit)

sli biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection guidance GO:0097485 241 0.999
axonogenesis GO:0007409 290 0.999
axon development GO:0061564 297 0.999
motor neuron axon guidance GO:0008045 58 0.998
Human
taxis GO:0042330 304 0.995
dendrite development GO:0016358 204 0.976
cardiac cell fate commitment GO:0060911 17 0.960
axon guidance GO:0007411 233 0.959
central nervous system development GO:0007417 201 0.954
Human Zebrafish Mouse Rat
tissue morphogenesis GO:0048729 297 0.935
negative regulation of transcription dna templated GO:0045892 237 0.933
morphogenesis of an epithelium GO:0002009 276 0.927
Human Zebrafish Mouse
substrate dependent cell migration GO:0006929 3 0.921
Human
cardioblast cell fate commitment GO:0042684 14 0.906
ventral cord development GO:0007419 16 0.901
cardioblast cell fate specification GO:0042685 9 0.895
regulation of cell growth GO:0001558 43 0.883
Human Zebrafish Mouse Rat Worm
regulation of dendrite morphogenesis GO:0048814 28 0.873
dendrite morphogenesis GO:0048813 199 0.871
glial cell migration GO:0008347 31 0.867
dendrite guidance GO:0070983 21 0.861
regulation of axon extension involved in axon guidance GO:0048841 4 0.854
Rat Worm
negative regulation of cellular biosynthetic process GO:0031327 277 0.851
epithelial cell migration GO:0010631 148 0.792
cell growth GO:0016049 108 0.788
Human Zebrafish Mouse Rat Worm
epithelial cell migration open tracheal system GO:0007427 32 0.785
growth GO:0040007 359 0.774
Human Zebrafish Mouse Rat Worm
regulation of cell differentiation GO:0045595 302 0.754
Human Zebrafish Mouse Rat Worm
salivary gland development GO:0007431 162 0.748
neuroblast development GO:0014019 13 0.736
positive regulation of nucleic acid templated transcription GO:1903508 266 0.729
roundabout signaling pathway GO:0035385 4 0.728
negative regulation of rna metabolic process GO:0051253 251 0.717
organ formation GO:0048645 39 0.717
axon choice point recognition GO:0016198 26 0.710
regulation of axon guidance GO:1902667 10 0.683
Human Rat Worm
regulation of cell fate commitment GO:0010453 29 0.683
exocrine system development GO:0035272 162 0.681
regulation of response to external stimulus GO:0032101 115 0.671
regulation of anatomical structure morphogenesis GO:0022603 242 0.670
Human Zebrafish Mouse Rat Worm
cell cell signaling involved in cell fate commitment GO:0045168 210 0.666
stem cell fate commitment GO:0048865 25 0.662
chemotaxis GO:0006935 249 0.658
negative regulation of axon extension GO:0030517 3 0.657
Zebrafish Mouse Rat Worm
tissue migration GO:0090130 155 0.656
heart morphogenesis GO:0003007 32 0.652
regulation of growth GO:0040008 233 0.650
Human Zebrafish Mouse Rat Worm
gliogenesis GO:0042063 80 0.647
axon midline choice point recognition GO:0016199 26 0.645
positive regulation of transcription dna templated GO:0045893 266 0.643
negative regulation of cell proliferation GO:0008285 69 0.641
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.641
regulation of dendrite development GO:0050773 37 0.633
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.631
regulation of cell fate specification GO:0042659 27 0.631
negative regulation of gene expression GO:0010629 387 0.623
Mouse
retinal ganglion cell axon guidance GO:0031290 12 0.608
Human Mouse
open tracheal system development GO:0007424 204 0.606
regulation of cell development GO:0060284 215 0.605
Human Zebrafish Mouse Rat Worm
head development GO:0060322 135 0.603
Human Mouse Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.597
compound eye development GO:0048749 307 0.588
dorsal ventral axon guidance GO:0033563 2 0.587
Mouse Worm
gland development GO:0048732 191 0.582
regulation of chemotaxis GO:0050920 12 0.579
cell fate determination GO:0001709 91 0.575
cardiac cell fate specification GO:0060912 10 0.557
epithelium migration GO:0090132 148 0.554
regulation of axonogenesis GO:0050770 32 0.552
Human Zebrafish Mouse Rat Worm
embryonic heart tube development GO:0035050 22 0.543
negative regulation of cell communication GO:0010648 223 0.539
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.536
positive regulation of axonogenesis GO:0050772 2 0.533
Zebrafish
neurological system process GO:0050877 358 0.527
regulation of cell proliferation GO:0042127 163 0.526
Mouse
cell fate specification GO:0001708 71 0.521
sensory organ morphogenesis GO:0090596 260 0.514
photoreceptor cell axon guidance GO:0072499 23 0.504
ovarian follicle cell migration GO:0007297 121 0.495
regulation of cell projection organization GO:0031344 92 0.493
Human Zebrafish Mouse Rat Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.479
negative regulation of cellular metabolic process GO:0031324 382 0.471
Human
ameboidal type cell migration GO:0001667 151 0.471
regulation of neuron differentiation GO:0045664 103 0.468
Human Zebrafish Mouse Rat Worm
salivary gland boundary specification GO:0007432 8 0.464
columnar cuboidal epithelial cell development GO:0002066 249 0.463
regulation of cardioblast differentiation GO:0051890 9 0.452
imaginal disc derived appendage morphogenesis GO:0035114 395 0.448
neuroblast differentiation GO:0014016 29 0.444
branching involved in open tracheal system development GO:0060446 45 0.437
cardioblast differentiation GO:0010002 20 0.424
border follicle cell migration GO:0007298 113 0.423
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.421
cell recognition GO:0008037 102 0.420
genital disc development GO:0035215 44 0.420
outflow tract morphogenesis GO:0003151 4 0.418
eye photoreceptor cell differentiation GO:0001754 145 0.415
ovarian follicle cell development GO:0030707 248 0.411
gland morphogenesis GO:0022612 145 0.397
Mouse
localization of cell GO:0051674 257 0.391
negative regulation of biosynthetic process GO:0009890 277 0.386
positive regulation of gene expression GO:0010628 290 0.385
eye development GO:0001654 323 0.382
formation of organ boundary GO:0010160 30 0.376
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.376
positive regulation of cellular biosynthetic process GO:0031328 316 0.372
glial cell differentiation GO:0010001 35 0.371
regulation of behavior GO:0050795 75 0.370
neuron recognition GO:0008038 101 0.368
regulation of neuron projection development GO:0010975 69 0.367
Human Zebrafish Mouse Rat Worm
epithelial tube morphogenesis GO:0060562 88 0.366
Human Mouse
forebrain development GO:0030900 2 0.352
Human Mouse
epithelial cell development GO:0002064 274 0.346
positive regulation of biosynthetic process GO:0009891 316 0.344
appendage development GO:0048736 401 0.341
negative regulation of nucleic acid templated transcription GO:1903507 240 0.329
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.328
stem cell differentiation GO:0048863 117 0.326
positive regulation of signal transduction GO:0009967 223 0.325
axon extension involved in axon guidance GO:0048846 10 0.325
Human Rat Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.324
negative regulation of cell fate specification GO:0009996 15 0.323
segment polarity determination GO:0007367 25 0.322
filopodium assembly GO:0046847 33 0.311
central complex development GO:0048036 9 0.311
tube development GO:0035295 244 0.309
determination of ventral identity GO:0048264 1 0.308
transcription from rna polymerase ii promoter GO:0006366 368 0.302
regulation of programmed cell death GO:0043067 152 0.297
Human
telencephalon development GO:0021537 2 0.296
Human Mouse
neuroblast fate commitment GO:0014017 19 0.284
eye photoreceptor cell fate commitment GO:0042706 37 0.283
phosphorylation GO:0016310 294 0.277
Human
heart formation GO:0060914 6 0.264
Zebrafish
regulation of cell morphogenesis GO:0022604 163 0.258
Human Zebrafish Mouse Rat Worm
neuron projection extension GO:1990138 32 0.255
Human Zebrafish Mouse Rat Worm
negative regulation of cell differentiation GO:0045596 143 0.253
Human Zebrafish Mouse Rat Worm
larval development GO:0002164 104 0.246
positive regulation of signaling GO:0023056 243 0.244
positive regulation of rna biosynthetic process GO:1902680 266 0.236
regulation of multicellular organismal development GO:2000026 414 0.235
regulation of cell migration GO:0030334 22 0.233
central nervous system projection neuron axonogenesis GO:0021952 6 0.232
Human Zebrafish
positive regulation of epithelial cell differentiation GO:0030858 1 0.229
kidney development GO:0001822 3 0.228
Human Mouse
response to organic substance GO:0010033 284 0.222
Human
cardiocyte differentiation GO:0035051 29 0.217
respiratory system development GO:0060541 213 0.214
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.214
morphogenesis of a branching epithelium GO:0061138 45 0.214
Human
developmental growth GO:0048589 280 0.212
Human Zebrafish Mouse Rat Worm
negative regulation of growth GO:0045926 84 0.208
Human Zebrafish Mouse Rat Worm
locomotory behavior GO:0007626 176 0.208
regulation of cellular component movement GO:0051270 42 0.206
cell migration GO:0016477 238 0.205
salivary gland morphogenesis GO:0007435 145 0.203
cell projection assembly GO:0030031 94 0.199
Human
regulation of cell size GO:0008361 63 0.197
Zebrafish Mouse Rat Worm
synaptic target recognition GO:0008039 45 0.194
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.192
negative regulation of chemotaxis GO:0050922 1 0.189
Human Rat Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.188
Human Zebrafish Mouse Rat Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.185
regulation of extent of cell growth GO:0061387 8 0.184
Zebrafish Mouse Rat Worm
embryonic development via the syncytial blastoderm GO:0001700 148 0.184
nephrocyte differentiation GO:0061319 12 0.182
immune system process GO:0002376 347 0.181
Human Mouse Rat
positive regulation of cell differentiation GO:0045597 64 0.180
Zebrafish
compound eye morphogenesis GO:0001745 249 0.180
regulation of catalytic activity GO:0050790 185 0.180
Human
regulation of nervous system development GO:0051960 248 0.178
Human Zebrafish Mouse Rat Worm
positive regulation of programmed cell death GO:0043068 62 0.177
Human
lamellipodium organization GO:0097581 21 0.174
Human
death GO:0016265 284 0.174
Human
negative regulation of cardioblast differentiation GO:0051892 7 0.172
regulation of organ morphogenesis GO:2000027 78 0.171
epithelial cell type specification open tracheal system GO:0035153 11 0.166
lateral inhibition GO:0046331 206 0.165
signal transduction by phosphorylation GO:0023014 107 0.164
mesodermal cell migration GO:0008078 7 0.163
renal system development GO:0072001 72 0.162
Human Mouse
brain development GO:0007420 120 0.159
Human Mouse Rat
cell proliferation GO:0008283 299 0.157
Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.156
Human
cardiovascular system development GO:0072358 82 0.154
compound eye photoreceptor cell differentiation GO:0001751 140 0.151
muscle cell differentiation GO:0042692 103 0.151
tube morphogenesis GO:0035239 191 0.150
olfactory bulb axon guidance GO:0071678 3 0.150
cell cell adhesion GO:0098609 26 0.150
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.149
developmental growth involved in morphogenesis GO:0060560 65 0.148
Human Zebrafish Mouse Rat Worm
regulation of cellular component size GO:0032535 98 0.146
Human Zebrafish Mouse Rat Worm
positive regulation of rna metabolic process GO:0051254 271 0.144
branch fusion open tracheal system GO:0035147 17 0.140
embryonic pattern specification GO:0009880 174 0.140
embryonic morphogenesis GO:0048598 206 0.139
ventral midline development GO:0007418 9 0.137
regulation of mapk cascade GO:0043408 92 0.136
positive regulation of axon guidance GO:1902669 1 0.135
memory GO:0007613 94 0.134
negative regulation of signaling GO:0023057 219 0.134
Human
epithelial cell differentiation GO:0030855 322 0.132
response to other organism GO:0051707 293 0.130
regulation of cell substrate adhesion GO:0010810 2 0.130
regulation of wnt signaling pathway GO:0030111 68 0.126
embryonic organ development GO:0048568 50 0.125
regulation of locomotion GO:0040012 42 0.124
neuron fate commitment GO:0048663 50 0.124
synapse organization GO:0050808 196 0.121
Zebrafish
cellular response to endogenous stimulus GO:0071495 80 0.121
Human
negative regulation of nervous system development GO:0051961 92 0.119
Human Zebrafish Mouse Rat Worm
regulation of epithelial cell migration GO:0010632 12 0.118
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.118
stem cell development GO:0048864 79 0.117
hematopoietic or lymphoid organ development GO:0048534 57 0.116
Mouse
developmental cell growth GO:0048588 52 0.115
Human Zebrafish Mouse Rat Worm
cell motility GO:0048870 251 0.115
regulation of neurogenesis GO:0050767 158 0.115
Human Zebrafish Mouse Rat Worm
regulation of cell motility GO:2000145 23 0.115
multi organism behavior GO:0051705 175 0.111
regulation of cell death GO:0010941 173 0.111
Human
response to endogenous stimulus GO:0009719 119 0.111
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.109
regulation of anatomical structure size GO:0090066 163 0.105
Human Zebrafish Mouse Rat Worm
single organism behavior GO:0044708 391 0.104
response to bacterium GO:0009617 198 0.104
somatic muscle development GO:0007525 66 0.103
eye photoreceptor cell development GO:0042462 81 0.101
circadian rhythm GO:0007623 105 0.101
response to oxygen containing compound GO:1901700 200 0.100
Human
axon extension GO:0048675 32 0.098
Human Zebrafish Mouse Rat Worm
ectodermal placode morphogenesis GO:0071697 4 0.097
positive regulation of response to external stimulus GO:0032103 44 0.097
positive regulation of cell communication GO:0010647 250 0.094
regulation of circadian rhythm GO:0042752 49 0.094
convergent extension GO:0060026 2 0.094
Zebrafish
cellular response to organic substance GO:0071310 132 0.093
Human
regulation of cell matrix adhesion GO:0001952 1 0.091
cellular response to hormone stimulus GO:0032870 44 0.091
Human
response to external biotic stimulus GO:0043207 293 0.090
neuron fate specification GO:0048665 12 0.088
negative regulation of multicellular organismal process GO:0051241 142 0.088
Human Zebrafish Mouse Rat Worm
development of primary sexual characteristics GO:0045137 50 0.088
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.088
body morphogenesis GO:0010171 2 0.087
periodic partitioning GO:0007365 29 0.087
regulation of molecular function GO:0065009 217 0.085
Human
compound eye photoreceptor fate commitment GO:0001752 36 0.083
positive regulation of response to stimulus GO:0048584 323 0.083
muscle structure development GO:0061061 224 0.083
epidermis development GO:0008544 65 0.082
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.082
regulation of intracellular signal transduction GO:1902531 236 0.081
Human
positive regulation of cellular component organization GO:0051130 156 0.080
Zebrafish
circulatory system development GO:0072359 82 0.080
synapse assembly GO:0007416 143 0.079
Zebrafish
urogenital system development GO:0001655 72 0.078
Human Mouse
response to extracellular stimulus GO:0009991 116 0.077
Rat
kidney epithelium development GO:0072073 3 0.076
Human
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.076
wnt signaling pathway GO:0016055 98 0.074
eye morphogenesis GO:0048592 260 0.073
positive regulation of cell death GO:0010942 69 0.072
Human
dorsal closure GO:0007391 79 0.072
cellular response to chemical stimulus GO:0070887 199 0.072
Human Rat
morphogenesis of embryonic epithelium GO:0016331 94 0.072
ectodermal placode development GO:0071696 4 0.071
positive regulation of endopeptidase activity GO:0010950 26 0.071
regulation of axon extension GO:0030516 8 0.070
Zebrafish Mouse Rat Worm
regulation of epithelial cell proliferation GO:0050678 4 0.070
reproductive system development GO:0061458 74 0.069
nephron development GO:0072006 3 0.069
positive regulation of cellular protein metabolic process GO:0032270 118 0.068
germ cell migration GO:0008354 43 0.067
hemopoiesis GO:0030097 46 0.067
Mouse
imaginal disc derived appendage development GO:0048737 399 0.066
positive regulation of molecular function GO:0044093 136 0.066
skin development GO:0043588 65 0.066
organic substance catabolic process GO:1901575 308 0.065
Human
response to biotic stimulus GO:0009607 294 0.065
detection of stimulus involved in sensory perception GO:0050906 92 0.065
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.064
negative regulation of cell fate commitment GO:0010454 17 0.064
cell migration involved in gastrulation GO:0042074 9 0.064
neuron remodeling GO:0016322 29 0.061
positive regulation of axon extension GO:0045773 2 0.061
Zebrafish
aggressive behavior GO:0002118 63 0.060
cell death GO:0008219 279 0.060
Human
negative regulation of response to stimulus GO:0048585 258 0.060
Human Rat Worm
negative regulation of signal transduction GO:0009968 206 0.059
Human
tube fusion GO:0035146 17 0.059
compound eye photoreceptor development GO:0042051 78 0.058
regulation of organ formation GO:0003156 3 0.058
limb development GO:0060173 1 0.058
positive regulation of cell projection organization GO:0031346 29 0.057
Zebrafish
digestive system development GO:0055123 149 0.057
stem cell proliferation GO:0072089 88 0.057
biological adhesion GO:0022610 138 0.056
r7 cell differentiation GO:0045466 43 0.056
renal filtration cell differentiation GO:0061318 12 0.056
defense response to bacterium GO:0042742 178 0.055
mapk cascade GO:0000165 107 0.055
reproductive behavior GO:0019098 122 0.055
gastrulation GO:0007369 70 0.055
determination of imaginal disc primordium GO:0007445 11 0.055
regulation of localization GO:0032879 275 0.054
spermatogenesis GO:0007283 200 0.054
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.054
heart development GO:0007507 82 0.054
defense response to other organism GO:0098542 225 0.054
blastoderm segmentation GO:0007350 159 0.054
renal tubule development GO:0061326 64 0.053
photoreceptor cell differentiation GO:0046530 170 0.053
nephron epithelium development GO:0072009 3 0.053
positive regulation of catalytic activity GO:0043085 118 0.052
cellular response to oxidative stress GO:0034599 28 0.052
cellular response to oxygen containing compound GO:1901701 79 0.052
Human
morphogenesis of a branching structure GO:0001763 45 0.051
Human Zebrafish
long term memory GO:0007616 62 0.051
reproductive structure development GO:0048608 74 0.051
regulation of cell cell adhesion GO:0022407 21 0.051
hair cell differentiation GO:0035315 47 0.050
small gtpase mediated signal transduction GO:0007264 88 0.049
Human
brain morphogenesis GO:0048854 16 0.049
determination of dorsal ventral asymmetry GO:0048262 3 0.049
stem cell fate determination GO:0048867 15 0.048
segmentation GO:0035282 207 0.048
positive regulation of phosphate metabolic process GO:0045937 139 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.048
Human
positive regulation of multicellular organismal process GO:0051240 143 0.048
Zebrafish
signal transduction in response to dna damage GO:0042770 3 0.047
regulation of rac protein signal transduction GO:0035020 3 0.047
gonad development GO:0008406 50 0.047
regulation of proteolysis GO:0030162 87 0.047
positive regulation of neuron differentiation GO:0045666 26 0.047
Zebrafish
sensory perception of chemical stimulus GO:0007606 116 0.046
response to ionizing radiation GO:0010212 32 0.045
determination of bilateral symmetry GO:0009855 13 0.045
cognition GO:0050890 141 0.045
single organism cell adhesion GO:0098602 47 0.044
regulation of cell cycle GO:0051726 291 0.044
hemocyte differentiation GO:0042386 38 0.044
appendage morphogenesis GO:0035107 397 0.043
mushroom body development GO:0016319 70 0.043
negative regulation of response to external stimulus GO:0032102 22 0.043
Human Rat Worm
neuroblast fate determination GO:0007400 12 0.042
positive regulation of intracellular signal transduction GO:1902533 116 0.042
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.041
lymph gland development GO:0048542 28 0.041
regulation of photoreceptor cell axon guidance GO:2000289 5 0.040
digestive tract development GO:0048565 149 0.040
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.040
startle response GO:0001964 16 0.040
regulation of embryonic development GO:0045995 68 0.039
male gamete generation GO:0048232 201 0.039
morphogenesis of a polarized epithelium GO:0001738 93 0.039
regulation of photoreceptor cell differentiation GO:0046532 34 0.038
response to alcohol GO:0097305 95 0.038
Human
camera type eye development GO:0043010 4 0.037
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.037
Human Rat Worm
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.037
cellular ketone metabolic process GO:0042180 24 0.037
positive regulation of cellular component biogenesis GO:0044089 80 0.037
pharynx development GO:0060465 1 0.036
positive regulation of hydrolase activity GO:0051345 78 0.036
cuticle development GO:0042335 86 0.036
glial cell development GO:0021782 27 0.036
mesodermal cell fate specification GO:0007501 2 0.036
camera type eye morphogenesis GO:0048593 2 0.035
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.035
digestive tract morphogenesis GO:0048546 127 0.035
photoreceptor cell fate commitment GO:0046552 41 0.035
regulation of cell cycle process GO:0010564 181 0.035
rac protein signal transduction GO:0016601 3 0.035
single organism biosynthetic process GO:0044711 206 0.035
response to abiotic stimulus GO:0009628 341 0.035
immune system development GO:0002520 57 0.035
Mouse
developmental induction GO:0031128 3 0.035
cellular response to starvation GO:0009267 61 0.034
leg disc development GO:0035218 92 0.034
nephron tubule morphogenesis GO:0072078 3 0.034
positive regulation of proteolysis GO:0045862 52 0.034
catabolic process GO:0009056 409 0.033
Human
formation of anatomical boundary GO:0048859 37 0.033
regulation of microtubule based process GO:0032886 49 0.033
cell division GO:0051301 248 0.032
negative regulation of cell development GO:0010721 62 0.032
Human Zebrafish Mouse Rat Worm
regionalization GO:0003002 416 0.032
positive regulation of retinal cell programmed cell death GO:0046670 9 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
sensory perception of smell GO:0007608 80 0.031
negative regulation of cardiac cell fate specification GO:2000044 7 0.031
post embryonic appendage morphogenesis GO:0035120 385 0.031
protein transport GO:0015031 155 0.031
glandular epithelial cell differentiation GO:0002067 1 0.030
regulation of protein metabolic process GO:0051246 256 0.030
Human
regulation of peptidase activity GO:0052547 39 0.030
endodermal cell fate commitment GO:0001711 3 0.029
positive regulation of mapk cascade GO:0043410 63 0.029
lamellipodium assembly GO:0030032 21 0.029
Human
positive regulation of protein metabolic process GO:0051247 128 0.029
instar larval development GO:0002168 55 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.028
Mouse
aging GO:0007568 143 0.028
negative regulation of neurogenesis GO:0050768 53 0.028
Human Zebrafish Mouse Rat Worm
regulation of retinal cell programmed cell death GO:0046668 18 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
regulation of protein modification process GO:0031399 112 0.028
Human
vesicle mediated transport GO:0016192 381 0.027
regulation of hemocyte differentiation GO:0045610 22 0.027
muscle tissue morphogenesis GO:0060415 2 0.027
regulation of response to oxidative stress GO:1902882 4 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
positive regulation of cell development GO:0010720 61 0.027
Zebrafish
positive regulation of phosphorylation GO:0042327 87 0.027
r3 r4 cell differentiation GO:0048056 12 0.026
organelle assembly GO:0070925 198 0.026
ventral furrow formation GO:0007370 17 0.026
developmental programmed cell death GO:0010623 138 0.026
negative regulation of behavior GO:0048521 8 0.026
Human Rat Worm
dna metabolic process GO:0006259 227 0.026
axis elongation GO:0003401 3 0.026
anatomical structure homeostasis GO:0060249 97 0.026
compound eye cone cell fate commitment GO:0042676 5 0.026
entrainment of circadian clock GO:0009649 16 0.025
neuromuscular junction development GO:0007528 149 0.025
limb morphogenesis GO:0035108 1 0.025
organ induction GO:0001759 3 0.025
nephron morphogenesis GO:0072028 3 0.025
positive regulation of neurogenesis GO:0050769 41 0.025
Zebrafish
single organismal cell cell adhesion GO:0016337 45 0.025
response to fibroblast growth factor GO:0071774 10 0.025
neuron fate determination GO:0048664 1 0.025
neuroblast division GO:0055057 35 0.025
central nervous system neuron differentiation GO:0021953 8 0.024
Human Zebrafish
cellular response to dna damage stimulus GO:0006974 223 0.024
establishment of planar polarity GO:0001736 87 0.024
regulation of glial cell differentiation GO:0045685 1 0.024
protein modification by small protein conjugation or removal GO:0070647 106 0.024
response to organic cyclic compound GO:0014070 89 0.024
Human
cellular response to acid chemical GO:0071229 8 0.024
macromolecule catabolic process GO:0009057 161 0.024
regulation of response to nutrient levels GO:0032107 18 0.024
regulation of phosphorylation GO:0042325 147 0.023
Human
post embryonic hemopoiesis GO:0035166 17 0.023
positive regulation of neuron projection development GO:0010976 14 0.023
Zebrafish
hindgut development GO:0061525 58 0.023
establishment of tissue polarity GO:0007164 87 0.023
oenocyte differentiation GO:0001742 8 0.023
ras protein signal transduction GO:0007265 88 0.023
neuromuscular process GO:0050905 21 0.022
compound eye retinal cell programmed cell death GO:0046667 23 0.022
cell aging GO:0007569 2 0.022
larval lymph gland hemopoiesis GO:0035167 17 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
sex differentiation GO:0007548 81 0.022
positive regulation of immune system process GO:0002684 68 0.022
intracellular signal transduction GO:0035556 300 0.022
Human
positive regulation of cell migration GO:0030335 2 0.022
stress activated protein kinase signaling cascade GO:0031098 55 0.021
regulation of jnk cascade GO:0046328 40 0.021
photoreceptor cell development GO:0042461 96 0.021
neuronal stem cell division GO:0036445 35 0.021
regulation of phosphatase activity GO:0010921 3 0.021
negative regulation of stem cell differentiation GO:2000737 8 0.021
negative regulation of cell growth GO:0030308 11 0.021
Human Zebrafish Mouse Rat Worm
positive regulation of cell motility GO:2000147 3 0.021
cellular response to nitrogen compound GO:1901699 51 0.020
Human
regulation of phosphate metabolic process GO:0019220 210 0.020
Human
nephron tubule development GO:0072080 3 0.020
positive regulation of nervous system development GO:0051962 69 0.020
Zebrafish
programmed cell death GO:0012501 257 0.020
Human
positive chemotaxis GO:0050918 4 0.020
endoderm formation GO:0001706 3 0.020
positive regulation of apoptotic process GO:0043065 47 0.020
Human
regulation of cellular response to stress GO:0080135 89 0.020
innate immune response GO:0045087 144 0.020
zymogen activation GO:0031638 20 0.019
positive regulation of wnt signaling pathway GO:0030177 25 0.019
epidermal cell differentiation GO:0009913 51 0.019
specification of symmetry GO:0009799 13 0.019
cellular response to nutrient levels GO:0031669 62 0.019
mesoderm development GO:0007498 78 0.019
regulation of response to stress GO:0080134 200 0.019
Rat
negative regulation of cell death GO:0060548 81 0.019
mesoderm formation GO:0001707 21 0.019
regulation of stem cell differentiation GO:2000736 14 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
small molecule metabolic process GO:0044281 305 0.018
Human
leg disc pattern formation GO:0035223 11 0.018

sli disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.322
urinary system disease DOID:18 0 0.322
musculoskeletal system disease DOID:17 0 0.035
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
connective tissue disease DOID:65 0 0.026