Drosophila melanogaster

43 known processes

Tcp-1eta (Dmel_CG8351)

CG8351 gene product from transcript CG8351-RA

(Aliases: CG8351,Dmel\CG8351,Tcp-1-eta1,Cct7)

Tcp-1eta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic microtubule organization GO:0031122 22 0.768
mitotic spindle organization GO:0007052 220 0.694
spindle organization GO:0007051 253 0.662
cell recognition GO:0008037 102 0.638
Mouse
protein complex biogenesis GO:0070271 201 0.516
spindle assembly involved in mitosis GO:0090307 50 0.496
spindle assembly GO:0051225 80 0.474
organelle fission GO:0048285 340 0.461
negative regulation of gene expression GO:0010629 387 0.400
protein complex assembly GO:0006461 200 0.398
single fertilization GO:0007338 24 0.366
Mouse
small molecule metabolic process GO:0044281 305 0.360
cell death GO:0008219 279 0.331
Worm
single organism catabolic process GO:0044712 228 0.292
negative regulation of cellular metabolic process GO:0031324 382 0.282
cellular macromolecular complex assembly GO:0034622 153 0.276
larval development GO:0002164 104 0.272
Worm
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.271
embryo development ending in birth or egg hatching GO:0009792 152 0.263
Worm
organonitrogen compound metabolic process GO:1901564 318 0.246
response to organic substance GO:0010033 284 0.226
cellular macromolecule localization GO:0070727 220 0.212
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.209
purine containing compound metabolic process GO:0072521 155 0.209
death GO:0016265 284 0.198
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.183
endocytosis GO:0006897 310 0.174
Worm
fertilization GO:0009566 26 0.169
Mouse
cell motility GO:0048870 251 0.169
body morphogenesis GO:0010171 2 0.168
aging GO:0007568 143 0.166
gonad development GO:0008406 50 0.162
Worm
programmed cell death GO:0012501 257 0.160
Worm
nuclear division GO:0000280 332 0.160
macromolecular complex assembly GO:0065003 256 0.156
purine nucleotide metabolic process GO:0006163 146 0.151
purine nucleotide catabolic process GO:0006195 109 0.151
organelle assembly GO:0070925 198 0.149
catabolic process GO:0009056 409 0.149
ribonucleoside triphosphate catabolic process GO:0009203 108 0.149
ribonucleoside metabolic process GO:0009119 127 0.146
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.141
nucleoside catabolic process GO:0009164 112 0.137
response to abiotic stimulus GO:0009628 341 0.135
centrosome duplication GO:0051298 121 0.132
organophosphate catabolic process GO:0046434 112 0.124
vesicle mediated transport GO:0016192 381 0.115
Worm
ribose phosphate metabolic process GO:0019693 145 0.114
negative regulation of biosynthetic process GO:0009890 277 0.111
purine ribonucleoside metabolic process GO:0046128 127 0.109
single organism cellular localization GO:1902580 180 0.106
nucleoside triphosphate metabolic process GO:0009141 120 0.106
organonitrogen compound catabolic process GO:1901565 128 0.105
organophosphate metabolic process GO:0019637 195 0.105
purine ribonucleoside catabolic process GO:0046130 112 0.104
renal system development GO:0072001 72 0.102
glycosyl compound catabolic process GO:1901658 112 0.100
cellular catabolic process GO:0044248 372 0.099
appendage morphogenesis GO:0035107 397 0.098
regulation of multicellular organismal development GO:2000026 414 0.097
nucleoside triphosphate catabolic process GO:0009143 108 0.097
regulation of cell death GO:0010941 173 0.091
localization of cell GO:0051674 257 0.088
protein modification process GO:0036211 438 0.088
cellular nitrogen compound catabolic process GO:0044270 165 0.087
negative regulation of cellular biosynthetic process GO:0031327 277 0.085
regulation of protein metabolic process GO:0051246 256 0.085
sex differentiation GO:0007548 81 0.084
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.083
carbohydrate derivative metabolic process GO:1901135 217 0.083
nucleobase containing small molecule metabolic process GO:0055086 174 0.082
multicellular organismal aging GO:0010259 140 0.082
cell migration GO:0016477 238 0.082
negative regulation of transcription dna templated GO:0045892 237 0.082
regulation of transport GO:0051049 181 0.081
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.081
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.080
regulation of immune response GO:0050776 118 0.078
purine nucleoside metabolic process GO:0042278 127 0.077
immune response GO:0006955 246 0.077
protein transport GO:0015031 155 0.077
carbohydrate derivative catabolic process GO:1901136 118 0.077
nucleoside phosphate metabolic process GO:0006753 162 0.077
negative regulation of rna biosynthetic process GO:1902679 240 0.077
purine ribonucleotide catabolic process GO:0009154 109 0.076
response to temperature stimulus GO:0009266 106 0.076
aromatic compound catabolic process GO:0019439 166 0.073
centrosome organization GO:0051297 163 0.072
oxoacid metabolic process GO:0043436 103 0.071
nucleotide metabolic process GO:0009117 161 0.069
purine nucleoside catabolic process GO:0006152 112 0.069
ribonucleoside catabolic process GO:0042454 112 0.068
glycosyl compound metabolic process GO:1901657 127 0.068
protein localization GO:0008104 284 0.066
purine nucleoside triphosphate catabolic process GO:0009146 108 0.066
taxis GO:0042330 304 0.066
establishment of localization in cell GO:0051649 402 0.064
embryonic morphogenesis GO:0048598 206 0.064
response to biotic stimulus GO:0009607 294 0.064
intracellular protein transport GO:0006886 104 0.063
development of primary sexual characteristics GO:0045137 50 0.062
Worm
apoptotic process GO:0006915 159 0.061
Worm
posttranscriptional regulation of gene expression GO:0010608 145 0.061
phosphorylation GO:0016310 294 0.060
nucleoside phosphate catabolic process GO:1901292 110 0.060
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.059
organic substance transport GO:0071702 257 0.059
sensory organ morphogenesis GO:0090596 260 0.058
organic cyclic compound catabolic process GO:1901361 168 0.057
eye morphogenesis GO:0048592 260 0.056
positive regulation of multicellular organismal process GO:0051240 143 0.056
reproductive structure development GO:0048608 74 0.056
Worm
ribonucleoside monophosphate metabolic process GO:0009161 51 0.055
anterior posterior pattern specification GO:0009952 136 0.054
purine ribonucleotide metabolic process GO:0009150 145 0.053
cell proliferation GO:0008283 299 0.053
nucleobase containing compound catabolic process GO:0034655 165 0.053
regulation of phosphorus metabolic process GO:0051174 210 0.053
atp metabolic process GO:0046034 49 0.051
ribonucleoside triphosphate metabolic process GO:0009199 119 0.050
nucleotide catabolic process GO:0009166 109 0.050
regulation of cellular protein metabolic process GO:0032268 243 0.050
single organism intracellular transport GO:1902582 207 0.049
regulation of response to stress GO:0080134 200 0.049
establishment of protein localization GO:0045184 163 0.049
urogenital system development GO:0001655 72 0.049
regulation of catalytic activity GO:0050790 185 0.049
ribonucleoside monophosphate catabolic process GO:0009158 39 0.049
cellular protein complex assembly GO:0043623 71 0.048
determination of adult lifespan GO:0008340 137 0.048
purine nucleoside triphosphate metabolic process GO:0009144 119 0.046
cellular protein localization GO:0034613 160 0.046
negative regulation of multicellular organismal process GO:0051241 142 0.046
purine nucleoside monophosphate metabolic process GO:0009126 50 0.045
regulation of phosphate metabolic process GO:0019220 210 0.044
mitotic nuclear division GO:0007067 213 0.043
imaginal disc derived appendage development GO:0048737 399 0.043
response to oxygen containing compound GO:1901700 200 0.043
ribonucleotide metabolic process GO:0009259 145 0.043
regulation of defense response GO:0031347 102 0.042
organic substance catabolic process GO:1901575 308 0.041
regulation of response to biotic stimulus GO:0002831 63 0.040
developmental growth GO:0048589 280 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
reproductive system development GO:0061458 74 0.039
Worm
organic acid metabolic process GO:0006082 103 0.039
regulation of programmed cell death GO:0043067 152 0.039
regulation of anatomical structure morphogenesis GO:0022603 242 0.038
autophagy GO:0006914 108 0.038
intracellular signal transduction GO:0035556 300 0.038
post embryonic appendage morphogenesis GO:0035120 385 0.038
cellular protein modification process GO:0006464 438 0.037
regulation of cellular catabolic process GO:0031329 157 0.036
axon guidance GO:0007411 233 0.035
carboxylic acid metabolic process GO:0019752 92 0.035
single organism behavior GO:0044708 391 0.035
ribonucleotide catabolic process GO:0009261 109 0.034
cellular response to chemical stimulus GO:0070887 199 0.033
regulation of apoptotic process GO:0042981 130 0.033
kidney development GO:0001822 3 0.033
regulation of response to external stimulus GO:0032101 115 0.033
regulation of purine nucleotide catabolic process GO:0033121 48 0.032
nucleoside monophosphate metabolic process GO:0009123 52 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
chemotaxis GO:0006935 249 0.032
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
cellular amino acid metabolic process GO:0006520 61 0.032
protein targeting GO:0006605 64 0.031
positive regulation of cellular component organization GO:0051130 156 0.031
regulation of cell differentiation GO:0045595 302 0.031
nucleoside metabolic process GO:0009116 127 0.030
muscle structure development GO:0061061 224 0.030
response to other organism GO:0051707 293 0.030
camera type eye development GO:0043010 4 0.030
regulation of molecular function GO:0065009 217 0.029
response to extracellular stimulus GO:0009991 116 0.028
negative regulation of cell communication GO:0010648 223 0.028
dna metabolic process GO:0006259 227 0.028
purine containing compound catabolic process GO:0072523 112 0.028
pole plasm rna localization GO:0007316 52 0.028
response to wounding GO:0009611 94 0.028
genitalia development GO:0048806 26 0.028
Worm
negative regulation of signaling GO:0023057 219 0.027
connective tissue development GO:0061448 3 0.027
gene silencing GO:0016458 138 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
humoral immune response GO:0006959 117 0.026
protein polymerization GO:0051258 42 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.025
atp catabolic process GO:0006200 38 0.025
establishment of protein localization to organelle GO:0072594 62 0.025
regulation of developmental growth GO:0048638 174 0.024
positive regulation of molecular function GO:0044093 136 0.024
response to external biotic stimulus GO:0043207 293 0.024
regulation of localization GO:0032879 275 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
positive regulation of developmental process GO:0051094 143 0.023
appendage development GO:0048736 401 0.023
receptor mediated endocytosis GO:0006898 21 0.023
Worm
biological adhesion GO:0022610 138 0.023
segmentation GO:0035282 207 0.023
negative regulation of cell death GO:0060548 81 0.023
negative regulation of phosphorus metabolic process GO:0010563 45 0.023
myotube cell development GO:0014904 3 0.023
response to nutrient levels GO:0031667 114 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
intracellular transport GO:0046907 228 0.022
regulation of catabolic process GO:0009894 170 0.022
regulation of cellular component biogenesis GO:0044087 201 0.021
negative regulation of developmental process GO:0051093 201 0.021
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
head development GO:0060322 135 0.021
chaperone mediated protein folding GO:0061077 2 0.021
response to peptide hormone GO:0043434 29 0.021
blastoderm segmentation GO:0007350 159 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
phagocytosis GO:0006909 215 0.020
anterior posterior axis specification GO:0009948 109 0.020
heterocycle catabolic process GO:0046700 166 0.020
regulation of vesicle mediated transport GO:0060627 59 0.020
endomembrane system organization GO:0010256 119 0.020
cellular response to external stimulus GO:0071496 66 0.020
regulation of nucleoside metabolic process GO:0009118 50 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.019
cellular response to organic substance GO:0071310 132 0.018
protein catabolic process GO:0030163 101 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
microtubule organizing center organization GO:0031023 168 0.018
regulation of growth GO:0040008 233 0.018
cytoplasmic transport GO:0016482 130 0.018
immune system process GO:0002376 347 0.017
cellular response to extracellular stimulus GO:0031668 64 0.017
axis specification GO:0009798 167 0.017
response to light stimulus GO:0009416 124 0.017
eye development GO:0001654 323 0.017
cation transport GO:0006812 110 0.017
circulatory system development GO:0072359 82 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
growth GO:0040007 359 0.017
positive regulation of catabolic process GO:0009896 105 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
regulation of cell development GO:0060284 215 0.017
membrane organization GO:0061024 112 0.016
meiotic cell cycle GO:0051321 171 0.016
protein transmembrane transport GO:0071806 4 0.016
regulation of proteolysis GO:0030162 87 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
translational elongation GO:0006414 4 0.016
activation of innate immune response GO:0002218 4 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
ion transport GO:0006811 145 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
interspecies interaction between organisms GO:0044419 16 0.015
chromatin organization GO:0006325 207 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
mitochondrion organization GO:0007005 65 0.015
negative regulation of molecular function GO:0044092 51 0.015
regulation of hydrolase activity GO:0051336 97 0.015
ncrna metabolic process GO:0034660 43 0.015
single organism membrane organization GO:0044802 93 0.014
response to hormone GO:0009725 45 0.014
translation GO:0006412 69 0.014
spermatogenesis GO:0007283 200 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
response to radiation GO:0009314 155 0.014
response to nitrogen compound GO:1901698 90 0.014
positive regulation of gene expression GO:0010628 290 0.013
transmembrane transport GO:0055085 139 0.013
embryonic organ development GO:0048568 50 0.013
regulation of innate immune response GO:0045088 71 0.013
protein localization to organelle GO:0033365 82 0.013
chromatin modification GO:0016568 147 0.013
purine nucleoside monophosphate catabolic process GO:0009128 38 0.013
proteolysis GO:0006508 192 0.013
mitotic spindle elongation GO:0000022 81 0.013
protein import GO:0017038 55 0.013
positive regulation of cell migration GO:0030335 2 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
generation of precursor metabolites and energy GO:0006091 42 0.013
cell cycle phase transition GO:0044770 140 0.013
positive regulation of developmental growth GO:0048639 62 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
regulation of organelle organization GO:0033043 196 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
rna splicing GO:0008380 83 0.012
defense response GO:0006952 300 0.012
centrosome cycle GO:0007098 137 0.012
antimicrobial humoral response GO:0019730 99 0.012
wound healing GO:0042060 75 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
protein targeting to mitochondrion GO:0006626 1 0.012
positive regulation of synapse assembly GO:0051965 29 0.012
embryonic pattern specification GO:0009880 174 0.012
tripartite regional subdivision GO:0007351 103 0.012
adult behavior GO:0030534 137 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
negative regulation of apoptotic process GO:0043066 63 0.011
embryonic axis specification GO:0000578 107 0.011
single organism biosynthetic process GO:0044711 206 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
epithelial cell differentiation GO:0030855 322 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
chromatin silencing GO:0006342 76 0.011
cytoplasm organization GO:0007028 64 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
rna processing GO:0006396 147 0.011
oocyte development GO:0048599 124 0.011
male gamete generation GO:0048232 201 0.011
energy derivation by oxidation of organic compounds GO:0015980 32 0.010
positive regulation of immune response GO:0050778 63 0.010
positive regulation of cell motility GO:2000147 3 0.010
response to decreased oxygen levels GO:0036293 58 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
regulation of protein complex disassembly GO:0043244 29 0.010
oocyte anterior posterior axis specification GO:0007314 72 0.010

Tcp-1eta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
disease of cellular proliferation DOID:14566 0 0.017
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.012
nervous system disease DOID:863 0 0.012